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I-TASSER Suite 5.2

( What is new in I-TASSER V5.2 Package?)

I-TASSER Suite is a package of standalone computer programs, developed for high-resolution protein structure prediction, refinement, and structure-based function annotations. A detailed instruction on how to download and install the Suite can be found at README5.2.txt. Please report bugs and questions at I-TASSER message board and some members will study the problems and answer them asap. The I-TASSER Suite is free for academic and non-profit researchers.

Through the I-TASSER License, the researchers have the access to the following standalone programs:

• I-TASSER: A standalone I-TASSER package for protein 3D structure prediction and refinement.
• COFACTOR: A program for ligand-binding site, EC number & GO term prediction.
• TM-SITE: A structure-based approach for ligand-binding site prediction.
• S-SITE: A sequence-based approach for ligand-binding site prediction.
• LOMETS: A set of locally installed threading programs for meta-server protein fold-recognition.
• MUSTER: A threading program to identify templates from a non-redundant protein structure library.
• SPICKER: A clustering program to identify near-native protein model from structure decoys.
• HAAD: A program for quickly adding hydrogen atoms to protein heavy-atom structures.
• EDTSurf: A program to construct triangulated surfaces of protein molecules.
• ModRefiner: A program to construct and refine atomic-level protein models from C-alpha traces.
• NW-align: A robust program for protein sequence-to-sequence alignments by Needleman-Wunsch algorithm.
• PSSpred: A highly accurate program for protein secondary structure prediction.
• ResQ: An algorithm to estimate B-factor and residue-level error of structural models.

The I-TASSER structural and functional template library is weekly updated and freelly accessible to the I-TASSER users.

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I-TASSER download:

• For academic users, please go to I-TASSER download webpage to download the I-TASSER Suite.
• If you need I-TASSER Suite for a commercial use, please contact us through yangzhanglab@umich.edu.

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Reference:

J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 2015, 12: 7-8 (Download the PDF file).