MetaGO result for job id PF14332

User Input

>UniRef100_UPI00046C9446/4-104 (101 residues)
RGTLKDFSLADIIQLVAFGQKTGVLRVVWPGGEASIHFVRGEVVHARSPNHVGEEAVYEL
FRIEDGQFEFHNSSEPPPERTITVDATNLVMEAARVLDESR

Download query sequence and structure

Proteins with similar structure

Top 10 structural analogs in PDB (as identified by TM-align)

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov.	Download Alignment
1	2c36A	0.46	4.34	0.043	0.812	Download
2	2gz4A	0.46	4.36	0.122	0.772	Download
3	4z3wA1	0.45	4.74	0.054	0.852	Download
4	1aorA	0.44	4.68	0.042	0.861	Download
5	5k8eA	0.44	4.12	0.049	0.752	Download
6	4ryaA2	0.44	4.44	0.071	0.822	Download
7	3rj8A	0.44	4.15	0.024	0.752	Download
8	5ntfA	0.44	4.51	0.075	0.802	Download
9	2bvgA	0.44	4.23	0.095	0.762	Download
10	3k01A	0.44	4.14	0.049	0.762	Download

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov. represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted Gene Ontology (GO) Terms

Molecular Function (MF)

GO term	Cscore^GO	Name
GO:0043169	0.02	cation binding

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Molecular Function. Confidently predicted terms are color coded by Cscore^GO:

[0.13,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Biological Process (BP)

GO term	Cscore^GO	Name
GO:0055114	0.01	oxidation-reduction process
GO:0046814	0.01	coreceptor-mediated virion attachment to host cell
GO:0045226	0.01	extracellular polysaccharide biosynthetic process
GO:0019064	0.01	fusion of virus membrane with host plasma membrane
GO:0015992	0.01	proton transport
GO:0009103	0.01	lipopolysaccharide biosynthetic process
GO:0006859	0.01	extracellular carbohydrate transport

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Biological Process. Confidently predicted terms are color coded by Cscore^GO:

[0.08,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Cellular Component (CC)

GO term	Cscore^GO	Name
GO:0055036	0.01	virion membrane
GO:0031224	0.01	intrinsic component of membrane
GO:0019031	0.01	viral envelope
GO:0019012	0.01	virion

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Cellular Component. Confidently predicted terms are color coded by Cscore^GO:

[0.14,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Reference:

Chengxin Zhang, Peter L Freddolino, and Yang Zhang. (2018) MetaGO: A Structure and Protein-Protein Interaction Network Based Pipeline for Automated Protein Function Annotations. Journal of Molecular Biology.

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