MetaGO result for job id PF11159

User Input

>UniRef100_A0A0D5LCV9/23-244 (222 residues)
VAAAAVVYAYASPYLALRQMRQAIDARDAQAISAYVDFPALRISLKQQLTDELMRRIDAQ
KRDNPLAIIGAMIGSALVGPLVDAYATPEGVAALMSGLPPRARPGQRPPELNRPGDQAAS
QAVTASAGAGAPPGSAGNADAARSPSPAASGAAAQTASAPAPDMPAAASGSPSGPSPQTS
AGYRSFDEFVVTYRRDDGSARYAAVFRRSGVLGWKLSAVDLH

Download query sequence and structure

Proteins with similar structure

Top 10 structural analogs in PDB (as identified by TM-align)

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov.	Download Alignment
1	4a01A	0.46	5.77	0.082	0.788	Download
2	5b5ec	0.44	5.45	0.045	0.734	Download
3	1jb0A	0.43	5.95	0.070	0.748	Download
4	1jb0B	0.43	5.86	0.089	0.743	Download
5	6fhjA	0.43	5.85	0.034	0.748	Download
6	4l37A	0.43	5.61	0.044	0.730	Download
7	5b5eB	0.43	5.33	0.081	0.689	Download
8	3wxvA	0.42	5.64	0.045	0.703	Download
9	1izlL	0.42	5.61	0.053	0.703	Download
10	3ixvM2	0.38	5.83	0.015	0.662	Download

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov. represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted Gene Ontology (GO) Terms

Molecular Function (MF)

GO term	Cscore^GO	Name
GO:0046906	0.03	tetrapyrrole binding
GO:0043169	0.03	cation binding
GO:0009055	0.03	electron carrier activity

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Molecular Function. Confidently predicted terms are color coded by Cscore^GO:

[0.13,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Biological Process (BP)

GO term	Cscore^GO	Name
GO:0044763	0.31	single-organism cellular process
GO:0060287	0.09	epithelial cilium movement involved in determination of left/right asymmetry
GO:0035082	0.09	axoneme assembly
GO:0022900	0.03	electron transport chain
GO:0019684	0.03	photosynthesis, light reaction
GO:0006464	0.03	cellular protein modification process

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Biological Process. Confidently predicted terms are color coded by Cscore^GO:

[0.08,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Cellular Component (CC)

GO term	Cscore^GO	Name
GO:0042651	0.04	thylakoid membrane
GO:0009579	0.04	thylakoid
GO:0009521	0.04	photosystem

Download full result of the above consensus prediction.

Click the graph to show a high resolution version.

(a)

Cscore^GO is the confidence score of predicted GO terms. Cscore^GO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.

(b)

The graph shows the predicted terms within the Gene Ontology hierachy for Cellular Component. Confidently predicted terms are color coded by Cscore^GO:

[0.14,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Reference:

Chengxin Zhang, Peter L Freddolino, and Yang Zhang. (2018) MetaGO: A Structure and Protein-Protein Interaction Network Based Pipeline for Automated Protein Function Annotations. Journal of Molecular Biology.

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