Cryo-EM density maps: The size of the cryo-EM density map should be less than 300M, and the resolution should be provided. Currently, our file type mode supports 8-bit, 16-bit, and 32-bit. The older MRC format (pre-2000) and unconventional one cannot be identified by our program. If you have a big cryo-EM density map, and you only want to generate the model of some regions, you should segment it manually or using UCSF Chimera first. Then you can submit the density map which corresponds to your amino acid sequence.