Table 1. PE5 proteins that have the C-score above 0 in the I-TASSER folding simulations.

Explanations:

neXtProt ID Name (HGNC Symbol) I-TASSER C-score(best cscore for multi-domain) COFACTOR F-score (GO molecular function) Is Multi-domain Subcellular localization SCOPe sccs SCOPe class SCOPe family HGNC reported by Kim included in PeptideAtlas2014-08
1 NX_A6NI03 TRIM64B 1.61 0.23 Y Cytoplasm b.29.1.0 All beta proteins automated matches gene with protein product Y N
2 NX_A6NLI5 TRIM64C 1.51 0.23 Y Cytoplasm b.29.1.0 All beta proteins automated matches gene with protein product N N
3 NX_Q6ZN08 ZNF66 1.24 0.42 Y Nucleus g.37.1.1 Small proteins "Classic zinc finger, C2H2" unknown N N
4 NX_Q5NE16 CTSL3P 1.12 0.9 N Extracell d.3.1.0 Alpha and beta proteins (a+b) automated matches pseudogene (id=0.45) N N
5 NX_A6NK02 TRIM75P 1.12 0.37 Y Cytoplasm b.29.1.22 All beta proteins SPRY domain pseudogene (id=0.47) N N
6 NX_A6NMB9 FIGNL2 1.12 0.7 Y Nucleus c.37.1.0 Alpha and beta proteins (a/b) automated matches unknown Y N
7 NX_P48741 HSPA7 1.09 0.98 Y Nucleus c.55.1.1 Alpha and beta proteins (a/b) Actin/HSP70 pseudogene (id=0.93) N N
8 NX_A6NGE7 URAD 1.07 0.67 N Extracell a.288.1.1 All alpha proteins UraD-like gene with protein product Y N
9 NX_A6NHM9 MOXD2P 1.03 0.06 Y Extracell b.121.1.2 All beta proteins "Peptidylglycine alpha-hydroxylating monooxygenase, PHM" pseudogene (id=0.40) N N
10 NX_Q96TA0 PCDHB18 0.92 0.48 Y Plasma membrane i.20.1.1 Low resolution protein structures Ep-cadherin pseudogene (id=0.78) N N
11 NX_A4D2B8 PMS2P1 0.91 0.57 Y Nucleus d.122.1.2 Alpha and beta proteins (a+b) "DNA gyrase/MutL, N-terminal domain" pseudogene (id=0.38) N N
12 NX_Q9H560 ANKRD19P 0.9 0.96 N Plasma membrane d.211.1.1 Alpha and beta proteins (a+b) Ankyrin repeat pseudogene (id=0.88) N N
13 NX_Q8N7Z5 ANKRD31 0.9 0.12 Y Cytoplasm d.211.1.0 Alpha and beta proteins (a+b) automated matches gene with protein product Y N
14 NX_O95397 PLEKHA8P1 0.89 0.44 Y Cytoplasm a.224.1.1 All alpha proteins "Glycolipid transfer protein, GLTP" pseudogene (id=0.97) N N
15 NX_Q6ZTB9 ZNF833P 0.89 0.91 N Nucleus k.12.1.1 Designed proteins Zinc finger design pseudogene (id=0.69) N N
16 NX_B5MCN3 SEC14L6 0.88 0.49 Y Cytoplasm c.13.1.0 Alpha and beta proteins (a/b) automated matches gene with protein product Y Y
17 NX_A0PJZ0 ANKRD20A5P 0.87 0.97 N Plasma membrane d.211.1.0 Alpha and beta proteins (a+b) automated matches pseudogene (id=0.92) N N
18 NX_C9J798 RASA4B 0.86 0.34 Y Plasma membrane a.116.1.2 All alpha proteins p120GAP domain-like gene with protein product N N
19 NX_A8MWD9 SNRPGP15 0.8 0.41 N Nucleus b.38.1.1 All beta proteins "Sm motif of small nuclear ribonucleoproteins, SNRNP" pseudogene (id=0.95) N N
20 NX_A4QPH2 PI4KAP2 0.79 0.69 Y Nucleus d.144.1.4 Alpha and beta proteins (a+b) "Phoshoinositide 3-kinase (PI3K), catalytic domain" pseudogene (id=0.93) N N
21 NX_Q6ZT77 ZNF826P 0.76 0.81 N Nucleus k.12.1.1 Designed proteins Zinc finger design pseudogene (id=0.50) N N
22 NX_A6NIE9 PRSS29P 0.73 0.97 Y Extracell b.47.1.0 All beta proteins automated matches pseudogene (id=0.46) N N
23 NX_Q8NGA4 GPR32P1 0.73 0.59 N Plasma membrane f.13.1.2 Membrane and cell surface proteins and peptides Rhodopsin-like pseudogene (id=0.83) N N
24 NX_P0C7Q3 FAM58BP 0.73 0.9 N Nucleus a.74.1.1 All alpha proteins Cyclin pseudogene (id=0.85) N N
25 NX_P0CB33 ZNF735P 0.71 0.12 Y Nucleus k.12.1.1 Designed proteins Zinc finger design pseudogene (id=0.81) Y Y
26 NX_E5RG02 PRSS46 0.71 0.81 Y Extracell b.47.1.2 All beta proteins Eukaryotic proteases gene with protein product N Y
27 NX_A6NEY8 PRORSD1P 0.69 0.49 N Cytoplasm d.116.1.1 Alpha and beta proteins (a+b) YbaK/ProRS associated domain pseudogene (id=0.27) N N
28 NX_Q9HAU6 TPT1P8 0.65 0.76 N Cytoplasm b.88.1.0 All beta proteins automated matches pseudogene (id=0.69) N N
29 NX_A8MUV8 ZNF727P 0.65 0.43 Y Nucleus k.12.1.1 Designed proteins Zinc finger design pseudogene (id=0.71) Y Y
30 NX_P12525 MYCLP1 0.63 0.31 Y Nucleus a.38.1.1 All alpha proteins "HLH, helix-loop-helix DNA-binding domain" pseudogene (id=0.73) N N
31 NX_P0C7X4 FTH1P19 0.62 0.9 Y Plasma membrane a.25.1.1 All alpha proteins Ferritin pseudogene (id=0.54) N N
32 NX_Q63ZY6 NSUN5P2 0.6 0.82 N Nucleus c.66.1.0 Alpha and beta proteins (a/b) automated matches pseudogene (id=0.76) N N
33 NX_A8MV57 MPTX1 0.6 0.68 N Extracell i.12.1.1 Low resolution protein structures "Proteins of incorrect, partial and unknown sequence" pseudogene (id=0.50) N N
34 NX_Q6NSI1 ANKRD26P1 0.6 0.94 N Nucleus d.211.1.1 Alpha and beta proteins (a+b) Ankyrin repeat pseudogene (id=0.54) N N
35 NX_Q8IWF7 UBE2DNL 0.59 0.56 N Nucleus d.20.1.1 Alpha and beta proteins (a+b) UBC-related pseudogene (id=0.71) N N
36 NX_A8MUU1 FABP5P3 0.58 0.46 N Cytoplasm b.60.1.2 All beta proteins Fatty acid binding protein-like pseudogene (id=0.91) N N
37 NX_Q9NSJ1 ZNF355P 0.54 0.36 Y Nucleus g.37.1.1 Small proteins "Classic zinc finger, C2H2" pseudogene (id=0.67) N N
38 NX_Q96P88 GNRHR2 0.54 0.51 N Plasma membrane f.13.1.2 Membrane and cell surface proteins and peptides Rhodopsin-like pseudogene (id=0.36) N N
39 NX_Q6ZUV0 N/A 0.53 0.3 N Cytoplasm d.38.1.1 Alpha and beta proteins (a+b) 4HBT-like NE N N
40 NX_Q58FG1 HSP90AA4P 0.5 0.36 Y Cytoplasm d.14.1.0 Alpha and beta proteins (a+b) automated matches pseudogene (id=0.87) N Y
41 NX_Q6P474 PDXDC2P 0.48 0.82 N Cytoplasm c.67.1.6 Alpha and beta proteins (a/b) Pyridoxal-dependent decarboxylase pseudogene (id=0.97) N N
42 NX_Q3KNT7 NSUN5P1 0.41 0.6 N Nucleus c.66.1.0 Alpha and beta proteins (a/b) automated matches pseudogene (id=0.91) N N
43 NX_A6NGU5 GGT3P 0.4 0.47 Y Extracell d.153.1.6 Alpha and beta proteins (a+b) Gamma-glutamyltranspeptidase-like pseudogene (id=0.98) N N
44 NX_Q6ZSU1 CYP2G1P 0.4 0.68 N Endoplasmic reticulum a.104.1.1 All alpha proteins Cytochrome P450 pseudogene (id=0.60) N N
45 NX_Q8IZP2 ST13P4 0.4 0.73 Y Cytoplasm a.118.8.1 All alpha proteins Tetratricopeptide repeat (TPR) pseudogene (id=0.97) N N
46 NX_Q7RTY9 PRSS41 0.39 0.98 Y Extracell b.47.1.2 All beta proteins Eukaryotic proteases unknown N N
47 NX_B5MD39 GGTLC3 0.34 0.92 N Extracell d.153.1.6 Alpha and beta proteins (a+b) Gamma-glutamyltranspeptidase-like unknown N N
48 NX_Q9BZ68 FRMD8P1 0.32 0.4 N Cytoplasm b.55.1.1 All beta proteins Pleckstrin-homology domain (PH domain) pseudogene (id=0.94) N N
49 NX_D6RBM5 USP17L23 0.31 0.7 N Nucleus a.251.1.1 All alpha proteins Phage replication organizer domain gene with protein product N N
50 NX_Q8NHW5 RPLP0P6 0.29 0.78 Y Nucleus i.1.1.1 Low resolution protein structures Ribosome complexes pseudogene (id=0.98) N N
51 NX_Q58FF6 HSP90AB4P 0.28 0.57 Y Centrosome d.122.1.2 Alpha and beta proteins (a+b) "DNA gyrase/MutL, N-terminal domain" pseudogene (id=0.82) N Y
52 NX_Q99463 NPY6R 0.27 0.68 N Plasma membrane f.13.1.2 Membrane and cell surface proteins and peptides Rhodopsin-like pseudogene (id=0.51) N N
53 NX_O60774 FMO6P 0.26 0.47 Y Endoplasmic reticulum c.3.1.5 Alpha and beta proteins (a/b) "FAD/NAD-linked reductases, N-terminal and central domains" pseudogene (id=0.71) N N
54 NX_Q7RTZ2 USP17L1P 0.23 0.91 Y Nucleus d.3.1.9 Alpha and beta proteins (a+b) "Ubiquitin carboxyl-terminal hydrolase, UCH" pseudogene (id=0.99) Y N
55 NX_A8MVU1 NCF1C 0.2 0.12 Y Cytoplasm b.34.2.0 All beta proteins automated matches pseudogene (id=0.99) N N
56 NX_P01893 HLA-H 0.2 0.97 Y Plasma membrane d.19.1.1 Alpha and beta proteins (a+b) MHC antigen-recognition domain pseudogene (id=0.87) N N
57 NX_Q15940 ZNF726P1 0.19 0.34 N Nucleus k.12.1.1 Designed proteins Zinc finger design pseudogene (id=0.76) N N
58 NX_Q9BYX7 POTEKP 0.19 0.99 N Cytoskeleton i.15.1.1 Low resolution protein structures Muscle protein complexes pseudogene (id=0.95) N N
59 NX_A4D1Z8 GRIFIN 0.13 0.98 N Extracell b.29.1.3 All beta proteins Galectin (animal S-lectin) gene with protein product N N
60 NX_O95744 PMS2P2 0.13 0.91 Y Nucleus d.122.1.2 Alpha and beta proteins (a+b) "DNA gyrase/MutL, N-terminal domain" pseudogene (id=0.54) N N
61 NX_Q5VTE0 EEF1A1P5 0.08 0.95 N Cytoplasm i.1.1.1 Low resolution protein structures Ribosome complexes pseudogene (id=1.00) N N
62 NX_P0CG00 ZSCAN5DP 0.06 0.12 Y Nucleus g.37.1.1 Small proteins "Classic zinc finger, C2H2" pseudogene (id=0.76) N N
63 NX_P0CF97 FAM200B 0.06 0.46 Y Nucleus c.55.3.12 Alpha and beta proteins (a/b) Hermes transposase-like gene with protein product Y N
64 NX_Q8WTZ4 CA5BP1 0.03 0.9 N Cytoplasm b.74.1.1 All beta proteins Carbonic anhydrase pseudogene (id=0.35) N N
65 NX_Q9NRI7 PPY2 0.02 0.14 N Extracell j.68.1.1 Peptides Fragments of the L-type calcium channel alpha subunit Cav.1 (dihydropyridine receptor) pseudogene (id=0.29) N N
66 NX_Q6ZRF7 ZNF818P 0 0.85 N Nucleus k.12.1.1 Designed proteins Zinc finger design pseudogene (id=0.47) N N
Reference: Qiwen Dong, Gilbert S. Omenn, Yang Zhang. A Bioinformatics Inspection of Missing Proteins in the Human Proteome. 2015 (submitted).