DAMpred results for job DAM100001 (your_protein) |
User Input
Download the protein sequence
>sequence
KLHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGPEASAFTKKM
VENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKPNNTHEQHL
RKSEAQAKKEKLNIWS
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Download the mutation list
By right-clicking on the images, you can change the
configurations, e.g. modifying the background color or stopping the spin of
your models. Download the predicted 3D model by I-TASSER
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Download the predicted results (">1" means Disease-associated Mutation).
Position |
Wild-type |
mutant type |
SD |
SN |
SΔ |
prediction |
20 |
L |
A |
0.216 |
0.838 |
-0.059 |
neutral |
105 |
K |
M |
0.561 |
0.570 |
0.270 |
neutral |
Download top 20 features with the lowest P-value (>> for further explanation of features...).
Position |
Wild-type |
mutant type |
PSICw |
PSICm |
dPSIC |
tPSICw |
dtPSIC |
noCw |
noCm |
noARm |
Intra |
CIntra |
20 |
L |
A |
0.471 |
0.056 |
-0.415 |
0.497 |
-0.231 |
8 |
5 |
3 |
0 |
0 |
105 |
K |
M |
0.704 |
-0.874 |
-1.578 |
0.55 |
0.133 |
4 |
5 |
6 |
0 |
0 |
Position |
Wild-type |
mutant type |
coswm |
rmsNwm |
rmsNSwm |
Pfamw |
Pfamm |
dPfam |
JSDi |
Depth |
dVDW |
CISRRm |
20 |
L |
A |
0.8 |
2.661 |
2.683 |
# |
# |
# |
0.471 |
9.09 |
2.365 |
7.270 |
105 |
K |
M |
0.6 |
2.062 |
1.612 |
2.712 |
3.667 |
0.954 |
0.289 |
4.87 |
0.779 |
3.151 |
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Please cite the following articles when you use the DAMpred server: |
1. | Lijun Quan, Hongjie Wu, Qiang Lyu
, and Yang Zhang, DAMpred: Recognizing disease-associated nsSNP mutations through Bayes-guided neural-network model built on low-resolution structure prediction of proteins and protein-protein interactions, Submitted (2018) |
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