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Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues |
| 1 | 0.20 | 1f3dJ | 0.425 | 3.80 | 0.071 | 0.686 | 0.64 | TPM | Download | 8,49,54,56 |
| 2 | 0.01 | 1indH | 0.471 | 4.02 | 0.065 | 0.752 | 0.66 | EOT | Download | 6,11,50,51 |
| 3 | 0.01 | 1kc5L | 0.396 | 4.24 | 0.057 | 0.686 | 0.61 | III | Download | 8,49,50 |
| 4 | 0.01 | 1kn4L | 0.429 | 3.93 | 0.047 | 0.694 | 0.67 | PDE | Download | 8,48,53,55,57 |
| 5 | 0.01 | 1m7dA | 0.432 | 3.85 | 0.058 | 0.694 | 0.67 | UUU | Download | 6,49,51,56 |
| 6 | 0.01 | 1qygH | 0.477 | 4.04 | 0.043 | 0.752 | 0.70 | BCG | Download | 8,49,51,55 |
| Click on the radio buttons to visualize predicted binding site and residues. |
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction. |
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
| (c) | TM-score is a measure of global structural similarity between query and template protein. |
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align. |
(e) | IDENa is the percentage sequence identity in the structurally aligned region. |
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein. |
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