>PF09462 (640 residues) LESGWHWLFTTLPLGEIDALGIARIGSRFSETCNNWKIVKQLLCPVLESYEPNTSASISY NTYCRALFHRCFHLINGWGWRDCKLILDTLYDFFARNTLYNLKQEENYTSPSFLDELDHN PSLDVTPSDPCFHIFLKIIASGLRSLSKRYDKKKVRNFAWRLLPNHGRVYPKEQPIHQAD LDALRNHHDLLCTLYFAVPDGCRPRLEAIKNLVHPANSHRETCNISIRSWARLVRFKLST DEDVSGLEAFADWHSYFVSEFIKQHMLARREIEAQNTKDNQFSHQLIERTISQNQRQIES LLKTALNSLQNAIQSAPTLEHAHRLISKSPISVVLGLFDPRLARVNTTVSEALQMLKAYV QKCSSASATGSANPPAPVDEDSQEYGDWADIEAMYGDEFSLATHPQGIEYMEKVLHPAVS QLVSNSFGEDHCPEDAILLNVVDCWTSIAQVLVKNGFRHWDNYLSLYDGDSWAVLRKTAQ TRKFTPKFLASCIEKDARFMCECKMQVLGMWMSSLVERVSMLKFQHSLTEALLNCDSNNT LLQNLPFSADRKDGRYSITLEQLSQRRLSLISSLLSNMRAHVQDLEITASRALSTEKQEY RELIQTMMSSMKANYQELGSSAASAQGAYVDFVHRVVGFL |
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Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
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Seq | LESGWHWLFTTLPLGEIDALGIARIGSRFSETCNNWKIVKQLLCPVLESYEPNTSASISYNTYCRALFHRCFHLINGWGWRDCKLILDTLYDFFARNTLYNLKQEENYTSPSFLDELDHNPSLDVTPSDPCFHIFLKIIASGLRSLSKRYDKKKVRNFAWRLLPNHGRVYPKEQPIHQADLDALRNHHDLLCTLYFAVPDGCRPRLEAIKNLVHPANSHRETCNISIRSWARLVRFKLSTDEDVSGLEAFADWHSYFVSEFIKQHMLARREIEAQNTKDNQFSHQLIERTISQNQRQIESLLKTALNSLQNAIQSAPTLEHAHRLISKSPISVVLGLFDPRLARVNTTVSEALQMLKAYVQKCSSASATGSANPPAPVDEDSQEYGDWADIEAMYGDEFSLATHPQGIEYMEKVLHPAVSQLVSNSFGEDHCPEDAILLNVVDCWTSIAQVLVKNGFRHWDNYLSLYDGDSWAVLRKTAQTRKFTPKFLASCIEKDARFMCECKMQVLGMWMSSLVERVSMLKFQHSLTEALLNCDSNNTLLQNLPFSADRKDGRYSITLEQLSQRRLSLISSLLSNMRAHVQDLEITASRALSTEKQEYRELIQTMMSSMKANYQELGSSAASAQGAYVDFVHRVVGFL | |||||||||||||||||||
1 | 3nowA | 0.10 | 0.08 | 3.15 | 1.25 | SPARKS-K | CVSTAQFCLQTILNALSGLKN--KPDSKPDKELRNNREIDTLLTCLVYSITDRTISGAARDGVIELITRNAERLVEI-------RGLCRLLDVCSELE-------------------DYKYESAMDITGSSSTIASVCLARIYENMYYDEAKARFTDQIDEYIKLLAP--------DMESKVRVTVAITALLVGNQVVARE--GILQMILAMATTDD--ELQQRVACECLIAAS----SKKDKAKALEQGVDILKRLYNDGIRVRALVGLCKLGSYAAIRPFGDGAALKLAEACRRFLIKIRRWAADGLAYLT---LDAECKEKLIEDKASIHALMDLARGGN--QSCLYGVVTTFVNLC-----NAYEKQEMLPEMIELAKFAKQHI-------PEEHELDDVDFINKRITVLANEGITTALCALAK---TESHNSQELIARVLNAVCGKVVQEGGVALLRMALEG----------TEKGKRHATQALARIGITIEVSFSGQRSLDVIRPLLNLLQQDCTALENFESLMALTNLASMNESVRQRIIKEQ--------GVSKIEYYLMYLTRAAAQCLCNLVIKMFEGNNDRVKFLALLCEETATACAGALAIITSVSVKAIASWLDILHTLIPAVQHRG | |||||||||||||
2 | 2x1gF | 0.09 | 0.08 | 3.04 | 1.78 | FFAS-3D | -ELAESCLKTMVNIIIQPDCHNYPK--------TAFVLIKMFLDSLSEITKTEWKRENDNEDIIVHIYMLFVSSVERHSTILVHRIVQEILHCTDKPGI-------------------------YPVEESCSTMALAFWYMLQDEVFAHKCWEYIKPLYAHLTRSEQPDEKSLAKWSSDDLECFRCRQDISDTFMYCYDVLNDYILEILAAMLDEAIAKLEACIYSFQSIPRLMRVLAEIPYEKLNLGTALETMGSYCNWLMYIPPAINLLVRGLNSSMSAQATLGLKELCRDCQLQLKPYADPLLNACHASLNTGRMKNSDSVRL-MFSIGKLMSLLRPE-----EIPKYLDIIVSPCFEELQAICQ----------ATPAARIRTIFRLNMISTNTPVLLVMQRTMPIFKRIAEEAACSAMKHAITRSQPMLQDLCLFIVASTLEISKTAIVMFFKPLQHSFKLFESTPEQNFSNISDTMETFFGCLTQIIKKIPQVLEDKTLRLVFYAQRGMLPESGAIRNSIQFLTHFVMQSRNHAHV-----------------TEVVLATGEQTLYTAMMCVRSQVDKFADILLAMNRKYAAEMAVWMKSLMADKTRYTALIIKEKVNKR-LLQQHLSEMA--- | |||||||||||||
3 | 6gmhQ | 0.12 | 0.09 | 3.20 | 0.39 | HHpred | ---------------------------------------------------GGVE-AMQAESCY--QLARSFHVQEDY---------DQAFQYYYQTQFAS------SSFLPFSQCFE--KVLKAYPNNYETMKILGSLY--AAS-EDQEKRDIAKGHLKKVTEQY----P-------DDVEAWIE----LAQILEQT--DIQGALSAYGTATRILQE-KVQADVPPEILNNVGALHFRLG----------------------NLGEAKKYFLASLDRADEHYYNAISVTTSYNLARLYEAFHEAEKLYKNILREHPNYVDCYLRLASDWFKEALQINQDH--------PDAWSLIGNLLAKQ-EWGPGQKKERILKQPSTQSDYSMLALLQTLH--QP--TRDREK---EKRH-QDRALAIYKQVLRNDAKNRRDVFADISDVWLNLAHIYVEQ--KQYISAVQMYE-NCLRKFYKH---QNTEV--VLYLARFKCGKLQECKQTLLK----ARHAPSTVLMVLQRLATSVLKDEK--SNLKE-----------VLNAVKELELAH-RYFSDLLSQAQYHVARARKQDEELRAKQEQEKELLRQKLLKEQEEKRLREKEELLEQRAQYVEKTKNILMFT | |||||||||||||
4 | 1b3uA | 0.11 | 0.09 | 3.25 | 1.13 | MUSTER | VQLRLNSIKKLSTIAL-------------ALGVE--RTRSELLPFLTDTIYDE-------DEVLLALAEQLGTFTTLVG---GPEYVHCLLPPLES-----ATVEETVKAVESLRAISHEHS---------PSDLEAHFVPLVKRLAGGDW-FTSRTSACGLFSVCYPRVSSAVKCSDDTPMVRRAAASKLGEFAKVLELDNVKSIPMFSNLASDEQ--DSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGP-EITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSA-DCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDEC-------PEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAED-------AKWRVRLAIIEYMPLLAGQLGVEFFD--EKLNS----LCMAWLVDHVYAREAATSNLKKLVEKFG--KEWAHATIIPKVLAMSGDPN--YLHRMTTLFCINVL------SEVCGQ---------DITTKHMLPTVLRMAANVRFNVAKSLQKIGPILD--NSTLQSEVKPILEKLTQD--------------QDVDVKYFAQEALTVL | |||||||||||||
5 | 4jlqA | 0.10 | 0.09 | 3.20 | 1.68 | CNFpred | -----IRSHAVACVNQFI---------------SRTQALMLHIDSFIENLFAGDEEPEVRKNVCRALVMLLEVRMDRLL-PHMHNIVEYMLQRTQD--DENVA----LEACEFWLTLAEQPICKD----VLVRHLPKLIPVLVNGMKY-NLRKCSAAALDVLANVYDELLPHILPLLKELLFHWVVKESGILVLGAIAMQGMIPYLPELIPHLIQCDKKALVRSITCWTLSRYAHWVVSQ-----------TYLKPLMTELLKRILDSNKRVQEAA-------CSAFATLEEEACTELVPYLAYILDTLVFAFSKYQ-HKNLLILYD--AIGTLADSVGHHLNK-PEYIQMLMPPLIQKWNMLKD-----EDKDLFP-------LECLSSVATALQSGF-----LPYCEPVYQRCVNLVQKTLAQAMLNYEAPDKDFMIVALDLLSGLAEGLG----GNIEQLVARSNTLMYQCMQDMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPFISVCNNATWAIGEISIQM-IPMVLHQLVEII-----NRPNTPKTLLENTAITIGRLGYVCPQEVAP--------------MLQQFIRPWCTSLRNIR------DNEEKDSAFRGICTMISVN | |||||||||||||
6 | 1vt4I | 0.12 | 0.09 | 3.12 | 1.07 | HHsearch-2 | --------------------------MDFE--T---GEHQYQYKDILSVFEAFVDMILSKEEIDHII-------MSK---DAVSGTLRLFWTLLSK--------QEE-MVQKFVE--------------EVLRINYKFLMSPIKTEQRQPSMEQRDRLY---NDNQVFAKYNVS--RLQPYLKLRQ------ALLELRPAKNVGVLGSGKTWVAL----DVCLSYKVQCKMDFKIFWLNLKN-CNSPETVLEMLQKLLYQIDPNWTSRS-----------DHSS---------N---IKLRIHSIQAELRRLLKSKPYENCLLVLLNV-QNAKAWNAFNLSCKILTLTPDEVKSLLLKYLDCRPQDLPREVL--TTNPRRLSII------AESIRDGLATCDKLTTIIESSLNVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMV---VV-NKLHKY--SLVEKQPKESTISIPSIYLELKVKLENE--YALHRSIVDHIPKTFD-SDDLIPPYLDQYFYSHIGHHL-----KNIEHP------------ERMTLFRMRFLEQKIRHD----STAW--NASGSILN----------TLQQLKFYKPYIC----DNDPKYERLVNAILDFL | |||||||||||||
7 | 3ea5B | 0.08 | 0.08 | 3.09 | 1.74 | Neff-PPAS | LEGRILAALTLKNELVSKDSVKTQQFAQRWITQVSPEAKNQIKTNALTALVSIE--PRIANAAAQLIAAIADIELPHGAWENVKRASLLALGYMCESADPQSQVSSSNNILIAIVQGAQSTETSKAVRLAALNALADSLIFIKNNMEREGERNYLMQVVCEATQAE-------------DIEVQAAAFGCLCKIMSKYYTFMKPEQALYALTIATMKSNDKVASMTVEFWSTICEEEIDIADDWNVSMSAGACLQLFAQNCGNHILEPVLEFVEQNITADGPDKVQRTYYVHQALPSILNLMNDQSLQVKETTAWCIADSVAESIDPQQHLPGVVQACLIGLQDHPKVATNCSWTIINLVEQLAEATPSPIYNGAANRIDNEFNARASAFSALTTMVEYATDTVAETSASISTFVMDKLGQTMSVDENQLTLEDAQSLQELQSNILTVLAAVIRKSPSSVEPVADMLMGLFFRLLEDSAFIEDDVFYAISALAASLGKGFEKYLETFSPYLLKALNQSITAVGFIADISNSLEEDFRRYAMMNVLAQMISNPNARRELKASNIGADFIPYLNDIMALCVAAQNTKPENGTLEALDYQIKVLEAVLDAYVGIVAGLHDKPEALFPYVGTIFQFIAQVAEDP | |||||||||||||
8 | 2pffB | 0.14 | 0.11 | 3.64 | 1.56 | HHsearch | ----------------MDAY--STRPLTLHGSLEHVLLVPTASFFIASLQEQFNKPFAADDEPTAELVGKFLGYVSSLVEPSFDQVLNLCL---TEFENCYLEGNDIHALAAKLLQEN---------DTTVKTK--ELIKNYITAMAKRPFDKKSNSALFRAVGEGNAQLVGNTDDYFEELRDLYQTYVLVGDLIKFSAETLSELINILEWLENPSNTPDKDYLLSIPICPLIGVIQLAH------YVVTAK-LLGFTPGELRSYLKG----------ATGHSQGLVSFFVSV-RKAITVLFFIGVRCYEA----YPNTSLPPSILEDS-LE--NNEPSPMLSISNLTQE----QVQDYVNKTNSHLPAGKQVEISVVSGPPQSYGLNLTLRKPSGLDQSPFSERKL------KFSNRFLPVASPFHSHLLVPASDLI----------NKDLVKNN-----VSFNAPVYDTFDGSDLRVLSGSISERIVDCIIRLP-VKWETT-TQF-------KATHI--LDFGPVLTH--RNKDGVRVIVATLDINPD---DDYGFKQGGGG------------------------GGGGGGGGG------------------------GGGGGGGGGGGGGGGGGG- | |||||||||||||
9 | 2bkuB | 0.08 | 0.08 | 3.10 | 1.76 | PROSPECTOR2 | FLQFAGLSSQVLIALTLKNELVSKDSVKTQQFAQRWIAKNQIKTNALTALVSIEP--RIANAAAQLIAAIADIELPHGAWPE---LMKIMVDNTGAEQMCESADALVSSSNNILIAI-VQGAQSTETSKAVRLAALNALADSLIFIKNNMEREGERNYLMQVV----CEATQAEDIEVQAAAF-----GCLCKIMSKYYTFMKPYMEQYALTIATMKSNDKVASMTVEFWSTICEEEIFPQSPLQSYNFALSSIKDVVPNLLNGNHILEPVLEFVEQNITADNWRNREAAVMADKVQRTYYVHQALPSILNLMNDQSLQVKETTAWPQQHLPGVVQACLIGLQDHPKVATNCSWTIINLVEQLAEATPSPIYNNRIDNEFNARASAFSALTTMVEYATDTVA---ETSASISTFVMDKLGQTMSVDENQLTLEDAQSLQELQSNILTVLAAVIRKS----PSSVEPVADMLMGLFKDSAFIEDDVFYAISALAASLGKGFEKYLETFSPYLLKALSLEEDFRRYSDAMMNVLAQ------MISNPNARREAQNTKPENGTLEALDYQIKVLEAVLDAYVGIVAGLHDK--------PEALFPYVGTIFQFIAQVAEPQLYSEDATSRAAVGLIGDIAAMF | |||||||||||||
10 | 5y81A | 0.10 | 0.01 | 0.53 | 0.19 | SAM | ------------------------------------NVLIRLFKLSFMSVNLFPNNEVVLLPHLNDLILNSLKYS---EPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQVLLQSLNQML---PHERELYVELCI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |