6gze D 2.49 BS01 GDP D 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V171 V177 S178 E183 N206 L209 Y224 L227 N228 V231 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 V169 V175 S176 E181 N204 L207 Y222 L225 N226 V229 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 6gze D 2.49 BS02 BEF D 1 G100 N101 G144 T145 G98 N99 G142 T143 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 6gze F 2.49 BS01 ACP F 1 P95 I148 K184 Y185 L186 K198 D200 R202 R222 D318 M320 I330 E331 N333 P93 I101 K102 Y103 L104 K116 D118 R120 R140 D205 M207 I217 E218 N220 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSCTWFPESYVNVWIKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTPYNEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLSIFIKLHH 6hzn A 2.41 BS01 MN A 1 H452 E470 A471 N481 H429 E447 A448 N458 5.1.3.19 Q9UL01 ITDENPEVMIPFTNANYDSHPMLYFSRAEVAELQLRAASSHEHIAARLTEAVHTMLSSPLEYLPPWDPKDYSARWNEIFGNNLGALAMFCVLYPENIEARDMAKDYMERMAAQPSWLVKDAPWDEVPLAHSLVGFATAYDFLYNYLSKTQQEKFLEVIANASGYMYETSYRRGWGFQYLHNHQPTNCMALLTGSLVLMNQGYLQEAYLWTKQVLTIMEKSLVLLREVTDGSLYEGVAYGSYTTRSLFQYMFLVQRHFNINHFGHPWLKQHFAFMYRTILPGFQRTVAIADSNYNWFYGPESQLVFLDKFVMRNGSGNWLADQIRRNRVVEGPGTPSKGQRWCTLHTEFLWYDGSLKSVPPPDFGTPTLHYFEDWGVVTYGSALPAEINRSFLSFKSGKLGGRAIYDIVHRNKYKDWIKGWRNFNAGHEHPDQNSFTFAPNGVPFITEALYGPKYTFFNNVLMFSPAVSKSCFSPWVGQVTEDCSSKWSKYKHDLAASCQGRVVAAEEKNGVVFIRGEGVGAYNPQLNLKNVQRNLILLHPQLLLLVDQIHLGEESPLETAASFFHNVDVPFEETVVDGVHGAFIRQRDGLYKMYWMDDTGYSEKATFASVTYPRGYPYNGTNYVNVTMHLRSPITRAAYLFIGPSIDVQSFTVHGDSQQLDVFIATSKHAYATYLWTGEATGQSAFAQVIADRHKILFDRNSAIKSSIVPEVKDYAAIVEQNLQHFKPVFQLLEKQILSRVRN 6imc A 2.51 BS01 MN A 1 H231 D233 H287 H212 D214 H268 1.14.11.-,1.14.11.51,4.2.99.18,1.14.11.33 P0CB42 EDAFRKLFRFYRQSRPGTADLGAVIDFSEAHLARSPKPGVPQVVRFPLNVSSVTERDAERVGLEPVSKWRAYGLEGYPGFIFIPNPFLPGCQRHWVKQCLKLYSQKPNVCNLDKHMTKEETQGLWEQSKEVLRSKEVTKRRPRSLLERLRWVTLGYHYNWDSKKYSADHYTPFPSDLAFLSEQVATACGFQGFQAEAGILNYYRLDSTLGIHVDRSELDHSKPLLSFSFGQSAIFLLGGLKRDEAPTAMFMHSGDIMVMSGFSRLLNHAVPRVLPHPDGECLPHCLETPLPAVLPSNSLVEPCSVEDWQVCATYLRTARVNMTVRQVLATGQDFPLEPV 6imc A 2.51 BS02 OGA A 1 N220 Y222 L228 H231 D233 H287 V289 R338 N340 T342 R344 N201 Y203 L209 H212 D214 H268 V270 R319 N321 T323 R325 1.14.11.-,1.14.11.51,4.2.99.18,1.14.11.33 P0CB42 EDAFRKLFRFYRQSRPGTADLGAVIDFSEAHLARSPKPGVPQVVRFPLNVSSVTERDAERVGLEPVSKWRAYGLEGYPGFIFIPNPFLPGCQRHWVKQCLKLYSQKPNVCNLDKHMTKEETQGLWEQSKEVLRSKEVTKRRPRSLLERLRWVTLGYHYNWDSKKYSADHYTPFPSDLAFLSEQVATACGFQGFQAEAGILNYYRLDSTLGIHVDRSELDHSKPLLSFSFGQSAIFLLGGLKRDEAPTAMFMHSGDIMVMSGFSRLLNHAVPRVLPHPDGECLPHCLETPLPAVLPSNSLVEPCSVEDWQVCATYLRTARVNMTVRQVLATGQDFPLEPV 6iqn A 2.54 BS01 AQ6 A 1 G517 E518 V524 A542 F589 E590 Y591 M592 H594 G595 D596 R599 L657 G17 E18 V24 A39 F83 E84 Y85 M86 H88 G89 D90 R93 L151 2.7.10.1 P04629 31699609 SVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFTDYYRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPV 6iqn A 2.54 BS02 AQ6 B 1 L731 S732 N733 E735 L213 S214 N215 E217 2.7.10.1 P04629 31699609 SVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFTDYYRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPV 6iqn B 2.54 BS02 AQ6 B 1 L516 G517 V524 A542 F589 E590 Y591 M592 R593 H594 G595 D596 R599 L657 L16 G17 V24 A39 F77 E78 Y79 M80 R81 H82 G83 D84 R87 L145 2.7.10.1 P04629 31699609 SVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLDKMLVAVKALDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAP 6izj A 2.10 BS01 NO3 A 1 W44 L60 G65 L66 Y94 P95 I96 W41 L57 G62 L63 Y91 P92 I93 A0A0D1FZV0 EAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIILRKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVLLFGQRDGRPLPKIFDNDDIQR 6j6t A 2.36 BS01 ZN A 1 D313 H315 D404 D166 H168 D257 3.5.1.98 Q8GXJ1 SSTAVGFDERMLLHSEFEVKAQPHPERPDRLRAIAASLATAGVFPGRCLPINAREITKQELQMVHTSEHVDAVDTTSQLLYSYFTSDTYANEYSARAARLAAGLCADLATDIFTGRVKNGFALVRPPGHHAGVRHAMGFCLHNNAAVAALVAQAAGAKKVLIVDWDVHHGNGTQEIFEQNKSVLYISLHRHEGGNFYPGTGAADEVGSNGGEGYCVNVPWSCGGVGDKDYIFAFQHVVLPIASAFSPDFVIISAGFDAARGDPLGCCDVTPAGYSRMTQMLGDLCGGKMLVILEGGYNLRSISASATAVIKVLLGELPIATTPSVAGLQTVLDVLNIQLEFWPSLAISYSKLL 6j6x B 2.96 BS01 MG B 1 D109 E318 V319 D95 E292 V293 2.5.1.60 P53611 PDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVN 6j76 A 2.37 BS01 NAP A 1 I146 T147 A148 W149 N150 K173 T175 S176 G206 G210 T225 G226 S227 A230 S233 I234 E248 L249 G250 C282 E383 F385 L411 H449 I144 T145 A146 W147 N148 K171 T173 S174 G204 G208 T223 G224 S225 A228 S231 I232 E246 L247 G248 C280 E381 F383 L409 H447 1.2.1.22 A0A090SK43 QYQMYVGGEWIDASNGQTEPVVSPINEEVLAYIQDADASDAERVLAVATTAQKEWAKQPARQRAEVLRKFAQLIRDNKQYLAELLVKEQGKLLKVALGEVEATSTFIEYACDWARQMDGDIVKSDNANEQIMIHKIPRGVVVAITAWNFPLALAGRKIGPALVAGNSIVVKPTSETPLATLELGYLAEQAGIPAGVLNIVTGGGRTLGNELVGHRMTNMVSMTGSTPAGQSIIRASANNMAHVQLELGGKAPFIVMEDADLEQAAAAALHSRFDNCGQVCTCNERMYVHGAVYDEFMRIFMGKVEAIKVGDPMDPASDMGPKVNANELAHMEELVAEAVDEGATVLFGGKKLEGPEFEKGFWFEPTVLTNVTQDMTIVHEESFGPILPVIKFDSFDEVIEYANDSDYGLAAMICTQNMHYINRLLTELESGEIYVNRGHGEQHQGFHNGYKLSGTGGEDGKYGFEQYLEKKTFYINY 6j76 B 2.37 BS01 NAP B 1 I146 T147 A148 W149 N150 K173 T175 S176 G206 R207 G210 N211 T225 G226 S227 A230 S233 I234 E248 L249 C282 E383 F385 L411 H449 I145 T146 A147 W148 N149 K172 T174 S175 G205 R206 G209 N210 T224 G225 S226 A229 S232 I233 E247 L248 C281 E382 F384 L410 H448 1.2.1.22 A0A090SK43 KQYQMYVGGEWIDASNGQTEPVVSPINEEVLAYIQDADASDAERVLAVATTAQKEWAKQPARQRAEVLRKFAQLIRDNKQYLAELLVKEQGKLLKVALGEVEATSTFIEYACDWARQMDGDIVKSDNANEQIMIHKIPRGVVVAITAWNFPLALAGRKIGPALVAGNSIVVKPTSETPLATLELGYLAEQAGIPAGVLNIVTGGGRTLGNELVGHRMTNMVSMTGSTPAGQSIIRASANNMAHVQLELGGKAPFIVMEDADLEQAAAAALHSRFDNCGQVCTCNERMYVHGAVYDEFMRIFMGKVEAIKVGDPMDPASDMGPKVNANELAHMEELVAEAVDEGATVLFGGKKLEGPEFEKGFWFEPTVLTNVTQDMTIVHEESFGPILPVIKFDSFDEVIEYANDSDYGLAAMICTQNMHYINRLLTELESGEIYVNRGHGEQHQGFHNGYKLSGTGGEDGKYGFEQYLEKKTFYIN 6j7f B 2.88 BS01 FAR B 1 Y30 S42 R46 G49 I50 W52 P288 F289 Y28 S40 R44 G47 I48 W50 P286 F287 2.5.1.60 P53611 TPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPELVS 6j7f B 2.88 BS02 GER B 1 L96 Q103 R144 F147 G192 Q193 Y195 C196 Y241 W244 F293 L94 Q101 R142 F145 G190 Q191 Y193 C194 Y239 W242 F291 2.5.1.60 P53611 TPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPELVS 6j7x A 2.75 BS01 GRG B 1 K135 Y195 N196 K129 Y175 N176 Q7Z6K3 EVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVEPRINLPHLLEEEVEFSTDLIDSYPGHETLWCHRRHIFYLQHHL 6j7x B 2.75 BS01 GRG B 1 Y51 L96 Q103 R144 F147 C148 H190 G192 Q193 C196 R232 K235 Y241 W244 F293 Y47 L92 Q99 R140 F143 C144 H186 G188 Q189 C192 R228 K231 Y237 W240 F289 2.5.1.60 P53611 QKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPELVS 6j8o B 1.86 BS01 III C 1 Y134 K168 K194 Y201 F202 R203 H204 S221 R222 R223 L226 H252 Y66 K100 K126 Y133 F134 R135 H136 S153 R154 R155 L158 H184 3.4.17.17 Q7L8A9 MDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKSLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRL 6j90 A 2.20 BS01 ATP A 1 N46 E50 D73 G77 I78 I94 A100 G101 G102 K103 Y109 G114 L115 H116 G117 V118 G119 V120 K337 N43 E47 D70 G74 I75 I91 A97 G98 G99 K100 Y106 G111 L112 H113 G114 V115 G116 V117 K334 5.99.1.3 P0A2I4 SYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMAFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPTGIHPSEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDTDKTGTMVRFWPSKSTFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTR 6j94 A 2.40 BS01 HEM A 1 K174 W197 R201 I255 A377 G378 T381 S382 V385 L435 Q440 L444 R446 P508 F509 G510 R514 K515 C516 I517 G518 F521 A522 N526 K51 W74 R78 I132 A254 G255 T258 S259 V262 L312 Q317 L321 R323 P385 F386 G387 R391 K392 C393 I394 G395 F398 A399 N403 1.14.-.- Q93VK5 RNEAFFIPLYELFLTYGGIFRLTFGPKSFLIVSDPSIAKHILKDNAKAYSKGILAEILDFVMGKGLIPADGEIWRRRRRAIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSLTNDTGVIEAVYTVLREAEDRSVSPIPVWDIPIWKDISPRQRKVATSLKLINDTLDDLIATCKRMVEEEELQFHEEYMNERDPSILHFLLASGDDVSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGDRFPTIQDMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDILGEYPIKRGEDIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQIAPGAPPVKMTTGATIHTTEGLKLTVTKRTKPLDIPSVPI 6j95 A 2.00 BS01 HEM A 1 K174 L189 I190 W197 R201 A377 G378 T381 S382 V385 Q440 L444 R446 P508 F509 G510 R514 C516 I517 G518 F521 A522 K48 L63 I64 W71 R75 A242 G243 T246 S247 V250 Q305 L309 R311 P373 F374 G375 R379 C381 I382 G383 F386 A387 1.14.-.- Q93VK5 AFFIPLYELFLTYGGIFRLTFGPKSFLIVSDPSIAKHILKDNAKAYSKGILAEILDFVMGKGLIPADGEIWRRRRRAIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSLTNDTGVIEAVYTVLREAEDRSVSPIPVWSPRQRKVATSLKLINDTLDDLIATCKRMVEEEELQFHEEYMNERDPSILHFLLASGDVSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGDRFPTIQDMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDILGEYPIKRGEDIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQIAPGAPPVKMTTGATIHTTEGLKLTVTKRTKPLDIPSVPI 6j95 A 2.00 BS02 RET A 1 F128 L177 I190 S288 I292 A377 T381 V443 T552 G553 A554 T555 F2 L51 I64 S162 I166 A242 T246 V308 T417 G418 A419 T420 1.14.-.- Q93VK5 AFFIPLYELFLTYGGIFRLTFGPKSFLIVSDPSIAKHILKDNAKAYSKGILAEILDFVMGKGLIPADGEIWRRRRRAIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSLTNDTGVIEAVYTVLREAEDRSVSPIPVWSPRQRKVATSLKLINDTLDDLIATCKRMVEEEELQFHEEYMNERDPSILHFLLASGDVSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGDRFPTIQDMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDILGEYPIKRGEDIFISVWNLHRSPLHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQIAPGAPPVKMTTGATIHTTEGLKLTVTKRTKPLDIPSVPI 6jj3 A 1.72 BS01 BS6 A 1 W81 V87 L92 L94 Y139 N140 I146 M149 W39 V45 L50 L52 Y97 N98 I104 M107 O60885 31789032 MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTE 6jjb A 1.51 BS01 BT0 A 1 W81 P82 F83 V87 L92 L94 C136 Y139 N140 W39 P40 F41 V45 L50 L52 C94 Y97 N98 O60885 31789032 MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTE 6khz A 2.80 BS01 ZN A 1 C128 C131 C151 C154 C8 C11 C31 C34 Q13501 31919097 GEEEDVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFP 6khz A 2.80 BS02 ZN A 2 C142 C145 H160 H163 C22 C25 H40 H43 Q13501 31919097 GEEEDVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFP 6koy A 2.35 BS01 TRP A 1 I149 L163 E165 L300 A301 L302 E303 H322 H326 E345 F391 Y396 I114 L128 E130 L265 A266 L267 E268 H287 H291 E310 F356 Y361 Q9RVZ5 31923495 QSVGDSIFPSLGQRGLDVQHYDLHLTVPRPGEPHLSGDVTLTVGAREPLSRIVLDLLGPRVSAAQWNGQRVRWVQTAQKVEVTLPRPLRPGETGRLRLIYAGTPELSGDPGLPIRPGWQNEAGLSYSLSEPHGTRGFLPCNDHPSDPATFTVRVTVPASASAAASGLFTTQTERNGLKTLTFTQRVPVPTYALGLIVGPLERRTAPDVQLGTQTVHRRDIYAAGLPAGTTVPEGETARMLRVLSDWFGPYPDEVYGVALLPVRQLALETAGLTTMPATSNRERVRLHALAHQWFGDQVTLADWADTWLSEGFATYAELLWAESQGEDGQAMAADWYARLSVLPSRPLRATREEEIFDASAYFRGALALHALRLKVGDAAFGQFLHSYVKTFTGRPVSTTALLTLVKTQLGAEAEQTLRVWVEGRTLPPLPEP 6koz B 2.25 BS02 LEU B 1 E165 A301 E303 E345 F391 Y396 E130 A266 E268 E310 F356 Y361 Q9RVZ5 31923495 QSVGDSIFPSLGQRGLDVQHYDLHLTVPRPGEPHLSGDVTLTVGAREPLSRIVLDLLGPRVSAAQWNGQRVRWVQTAQKVEVTLPRPLRPGETGRLRLIYAGTPELSGDPGLPIRPGWQNEAGLSYSLSEPHGTRGFLPCNDHPSDPATFTVRVTVPASASAAASGLFTTQTERNGLKTLTFTQRVPVPTYALGLIVGPLERRTAPDVQLGTQTVHRRDIYAAGLPAGTTVPEGETARMLRVLSDWFGPYPDEVYGVALLPVRQLALETAGLTTMPATSNRERVRLHALAHQWFGDQVTLADWADTWLSEGFATYAELLWAESQGEDGQAMAADWYARLSVLPSRPLRATREEEIFDASAYFRGALALHALRLKVGDAAFGQFLHSYVKTFTGRPVSTTALLTLVKTQLGAEAEQTLRVWVEGRTLPPLPEPV 6koz A 2.25 BS02 LEU A 1 E165 A301 E303 E345 Y396 E130 A266 E268 E310 Y361 Q9RVZ5 31923495 QSVGDSIFPSLGQRGLDVQHYDLHLTVPRPGEPHLSGDVTLTVGAREPLSRIVLDLLGPRVSAAQWNGQRVRWVQTAQKVEVTLPRPLRPGETGRLRLIYAGTPELSGDPGLPIRPGWQNEAGLSYSLSEPHGTRGFLPCNDHPSDPATFTVRVTVPASASAAASGLFTTQTERNGLKTLTFTQRVPVPTYALGLIVGPLERRTAPDVQLGTQTVHRRDIYAAGLPAGTTVPEGETARMLRVLSDWFGPYPDEVYGVALLPVRQLALETAGLTTMPATSNRERVRLHALAHQWFGDQVTLADWADTWLSEGFATYAELLWAESQGEDGQAMAADWYARLSVLPSRPLRATREEEIFDASAYFRGALALHALRLKVGDAAFGQFLHSYVKTFTGRPVSTTALLTLVKTQLGAEAEQTLRVWVEGRTLPPLPEPVGAP 6kp0 A 2.10 BS02 ARG A 1 P148 E165 L300 A301 L302 E303 H322 H326 F391 Y396 P112 E129 L264 A265 L266 E267 H286 H290 F355 Y360 Q9RVZ5 31923495 QSVGDSIFPSLGQRGLDVQHYDLHLTVPRPGEPHLSGDVTLTVGAREPLSRIVLDLLGPRVSAAQWNGQRVRWVQTAQKVEVTLPRPLRPGETGRLRLIYAGTPELSGDPLPIRPGWQNEAGLSYSLSEPHGTRGFLPCNDHPSDPATFTVRVTVPASASAAASGLFTTQTERNGLKTLTFTQRVPVPTYALGLIVGPLERRTAPDVQLGTQTVHRRDIYAAGLPAGTTVPEGETARMLRVLSDWFGPYPDEVYGVALLPVRQLALETAGLTTMPATSNRERVRLHALAHQWFGDQVTLADWADTWLSEGFATYAELLWAESQGEDGQAMAADWYARLSVLPSRPLRATREEEIFDASAYFRGALALHALRLKVGDAAFGQFLHSYVKTFTGRPVSTTALLTLVKTQLGAEAEQTLRVWVEGRTLPPLPEPV 6kp0 B 2.10 BS02 ARG B 1 I149 E165 L300 A301 L302 E303 H322 H326 E345 I114 E130 L265 A266 L267 E268 H287 H291 E310 Q9RVZ5 31923495 QSVGDSIFPSLGQRGLDVQHYDLHLTVPRPGEPHLSGDVTLTVGAREPLSRIVLDLLGPRVSAAQWNGQRVRWVQTAQKVEVTLPRPLRPGETGRLRLIYAGTPELSGDPGLPIRPGWQNEAGLSYSLSEPHGTRGFLPCNDHPSDPATFTVRVTVPASASAAASGLFTTQTERNGLKTLTFTQRVPVPTYALGLIVGPLERRTAPDVQLGTQTVHRRDIYAAGLPAGTTVPEGETARMLRVLSDWFGPYPDEVYGVALLPVRQLALETAGLTTMPATSNRERVRLHALAHQWFGDQVTLADWADTWLSEGFATYAELLWAESQGEDGQAMAADWYARLSVLPSRPLRATREEEIFDASAYFRGALALHALRLKVGDAAFGQFLHSYVKTFTGRPVSTTALLTLVKTQLGAEAEQTLRVWVEGRTLPPLPEPV 6kru C 2.30 BS01 GAL C 1 P244 N246 D249 K258 T260 P8 N10 D13 K22 T24 P01867 31878295 GPSVFIFPPNIKDVLMISLTPKVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTIRVVSTLPIQHQDWMSGKEFKCKVNNSPIERTISKIKGLVRAPQVYILPPPAEQLSRKDVSLTCLVVGFNPGDISVEWTSNGHTEENYKDTAPVLDSDGSYFIYSKLNMKTSKWEKTDSFSCNVRHEGLKNYYLKKTISR 6kru D 2.30 BS01 GAL D 1 P244 P245 N246 K258 T260 P8 P9 N10 K22 T24 P01867 31878295 GPSVFIFPPNIKDVLMISLTPKVTCVVVDVSPDVQISWFVNNVEVHTAQTQTHREDYNSTIRVVSTLPIQHQDWMSGKEFKCKVNNPSPIERTISKIKGLVRAPQVYILPPPAEQLSRKDVSLTCLVVGFNPGDISVEWTSNGHTEENYKDTAPVLDSDGSYFIYSKLNMKTSKWEKTDSFSCNVRHEGLKNYYLKKTISR 6lf7 A 1.79 BS06 OSM A 4 R76 P149 K150 N419 R76 P149 K150 N419 1.11.1.7 A0A452E9Y6 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQNKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKILAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHVTKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 6lf7 A 1.79 BS07 OSM A 5 E218 A219 E218 A219 1.11.1.7 A0A452E9Y6 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQNKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKILAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHVTKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 6lhn A 2.50 BS01 ZN A 1 C149 C172 C184 H187 C37 C60 C72 H75 2.3.2.27 F4KCC2 31919097 RLGSGGGVCGSVWGQNDIAYRCRTCENDPTCAICVPCFQNGDHNSHDYSIIYTGGGCCDCGDETAWKPDGFCSNHK 6lhn A 2.50 BS02 ZN A 2 C121 C146 C149 C170 C9 C34 C37 C58 2.3.2.27 F4KCC2 31919097 RLGSGGGVCGSVWGQNDIAYRCRTCENDPTCAICVPCFQNGDHNSHDYSIIYTGGGCCDCGDETAWKPDGFCSNHK 6lhn A 2.50 BS03 ZN A 3 C134 C137 H155 H158 C22 C25 H43 H46 2.3.2.27 F4KCC2 31919097 RLGSGGGVCGSVWGQNDIAYRCRTCENDPTCAICVPCFQNGDHNSHDYSIIYTGGGCCDCGDETAWKPDGFCSNHK 6nix A 2.10 BS01 III C 1 Q9 F24 A52 S53 F54 N62 N69 I72 Q6 F21 A49 S50 F51 N59 N66 I69 P01903 EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 6nix B 2.10 BS01 III C 1 H13 Y30 P56 D57 Y60 W61 L67 K71 Y78 H81 N82 V85 H12 Y29 P55 D56 Y59 W60 L66 K70 Y77 H80 N81 V84 P01911 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 6nkf A 2.23 BS01 SBT A 1 L20 P22 H37 S77 L19 P21 H36 S75 TNHIKEINWEQNTNSYIQLIPNIEYTKVEDTSLTLHLLVYRNPDALFNRKGNQETYPLIIYLQGCGWGWTKQDTSAFIPQLVPFVEQGYVVASVQYRGSGEAVFPAQLHDVKTAVRFLKANAARYNIDPDRVGVWGDSSGGHLALLLGLTEGIEEFEGPDEYRHVSSKVDAVADWFGPVDLLSSKYPSIFDHDSPNSPESKLIGGAVQENRVQAKQASPISYVHREAPPILIHGDQDDVVPYQQSVQLFEALIKEGHDALYKINGAGHNGFTQAHTLDIVKSFFRKHLKPGKAHHHH 6nkf D 2.23 BS01 SBT A 1 L20 P22 H37 S77 I80 L19 P21 H36 S75 I78 TNHIKEINWEQNTNSYIQLIPNIEYTKVEDTSLTLHLLVYRNPDALFNRKGNQETYPLIIYLQGCGWGWTKQDTSAFIPQLVPFVEQGYVVASVQYRGSGEAVFPAQLHDVKTAVRFLKANAARYNIDPDRVGVWGDSSGGHLALLLGLTEGIEEFEGPDEYRHVSSKVDAVADWFGPVDLLSSKYPSIFDHDSPNSPESKLIGGAVQENRVQAKQASPISYVHREAPPILIHGDQDDVVPYQQSVQLFEALIKEGHDALYKINGAGHNGFTQAHTLDIVKSFFRKHLKPG 6nmz A 2.40 BS01 KSJ A 1 T11 K15 D47 A73 P74 A110 G111 V115 T12 K16 D48 A74 P75 A111 G112 V116 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6nmz A 2.40 BS02 KSP A 1 T11 K15 T41 P71 A73 P74 A110 G111 T12 K16 T42 P72 A74 P75 A111 G112 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6nmz B 2.40 BS01 KSJ B 1 T11 K15 T41 R45 D47 P71 A73 P74 A110 G111 T12 K16 T42 R46 D48 P72 A74 P75 A111 G112 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nmz C 2.40 BS02 KSP C 1 T11 K15 T41 R45 P71 M72 A73 P74 A110 G111 V115 T13 K17 T43 R47 P73 M74 A75 P76 A112 G113 V117 6.3.3.3 P9WPQ5 HGGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6nmz D 2.40 BS01 KSJ D 1 T11 K15 T41 A73 P74 A110 G111 V115 T13 K17 T43 A75 P76 A112 G113 V117 6.3.3.3 P9WPQ5 HGGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nmz D 2.40 BS02 KSP D 1 T11 G12 K15 T41 P71 M72 A73 P74 A110 T13 G14 K17 T43 P73 M74 A75 P76 A112 6.3.3.3 P9WPQ5 HGGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nn0 A 2.34 BS01 KSJ A 1 T11 K15 D47 P71 A73 P74 A110 G111 V115 T12 K16 D48 P72 A74 P75 A111 G112 V116 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6nn0 B 2.34 BS01 CTN B 1 G12 V17 G169 S170 L196 P197 G199 A200 A201 G13 V18 G170 S171 L197 P198 G200 A201 A202 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nn0 B 2.34 BS02 KSJ B 1 T11 K15 R45 D47 P71 A73 A110 G111 T12 K16 R46 D48 P72 A74 A111 G112 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nn0 C 2.34 BS01 KSJ C 1 T11 G12 K15 R45 D47 P71 M72 A73 P74 A110 G111 T12 G13 K16 R46 D48 P72 M73 A74 P75 A111 G112 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6nn0 C 2.34 BS02 KSP C 1 T11 G12 K15 T41 R45 P71 A73 P74 A110 G111 T12 G13 K16 T42 R46 P72 A74 P75 A111 G112 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6nn0 D 2.34 BS03 CTN D 1 G12 V17 E52 G169 S170 L196 P197 A198 A200 A201 G14 V19 E54 G171 S172 L198 P199 A200 A202 A203 6.3.3.3 P9WPQ5 HGGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nn0 D 2.34 BS04 KSJ D 1 T11 G12 K15 R45 A73 P74 A110 G111 V115 T13 G14 K17 R47 A75 P76 A112 G113 V117 6.3.3.3 P9WPQ5 HGGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV 6nnz C 2.30 BS02 KUG C 1 T11 G12 K15 T41 R45 P71 M72 A73 P74 A110 G111 V115 T12 G13 K16 T42 R46 P72 M73 A74 P75 A111 G112 V116 6.3.3.3 P9WPQ5 GGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAAEHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAAQQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLVG 6noz A 1.95 BS01 ZN A 1 C123 C124 C149 H151 C125 C126 C151 H153 W8QLX4 SNNWDSHYGFDKAGEFHMLDHTGFAFPSEVVNGRRVLKTTDNNCWVNVTCLQLQFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAGSVTIERVTHDGCCCSKRVVTAPVVNASVLKLGVEDGLCPHGLNYIDKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLDNGNGVAGHYTVFDHDTGMVHDGDVFVPGDLNVSPVTNVVVSEQTAVVIKDPVK 6npr A 2.37 BS01 III R 1 Y7 Y59 E63 R66 N70 S73 F74 D77 T80 W97 A99 W114 F116 T143 K146 W147 Y159 E163 W167 Y171 Y6 Y58 E62 R65 N69 S72 F73 D76 T79 W96 A98 W113 F115 T142 K145 W146 Y158 E162 W166 Y170 P01900 31796585 SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRCYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGSDYIALNEDLKTWTAADMCAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWG 6npr C 2.37 BS01 III P 1 Y7 Y59 E63 R66 N70 S73 F74 D77 W97 A99 W114 T143 K146 W147 Y159 W167 Y171 Y6 Y58 E62 R65 N69 S72 F73 D76 W96 A98 W113 T142 K145 W146 Y158 W166 Y170 P01900 31796585 SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRCYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGSDYIALNEDLKTWTAADMCAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWG 6nq5 B 1.85 BS01 HEM B 1 F41 F42 H63 K66 A70 L91 H92 L96 L141 F41 F42 H63 K66 A70 L91 H92 L96 L141 P68871 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKY 6nq5 B 1.85 BS02 FE B 1 F42 L96 F42 L96 P68871 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKY 6nr0 A 2.45 BS02 KXJ A 1 F119 F131 L138 P140 F143 I169 H187 I232 V233 F234 F235 G236 E237 S238 L239 Q267 P268 F64 F76 L83 P85 F88 I114 H132 I177 V178 F179 F180 G181 E182 S183 L184 Q212 P213 3.5.1.- Q8IXJ6 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 6nr0 A 2.45 BS03 KXG A 1 G84 A85 G86 T89 D95 F96 R97 S98 F119 Q167 H187 F235 G261 T262 S263 V266 N286 K287 E288 G322 E323 C324 G29 A30 G31 T34 D40 F41 R42 S43 F64 Q112 H132 F180 G206 T207 S208 V211 N231 K232 E233 G256 E257 C258 3.5.1.- Q8IXJ6 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 6nr0 B 2.45 BS02 KXJ B 1 F119 F131 L134 L138 H187 I232 V233 F235 G236 E237 Q267 P268 F63 F75 L78 L82 H131 I176 V177 F179 G180 E181 Q211 P212 3.5.1.- Q8IXJ6 RLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 6o8e A 2.61 BS01 NUC C 1 H65 N66 K67 V90 S91 Y92 Y93 Y96 P98 K111 A113 I115 S141 V142 S143 Y146 F249 C251 F302 S304 G305 E307 Q346 M350 R357 N374 L453 T454 K455 H476 S477 R484 I502 N503 L504 F527 H64 N65 K66 V89 S90 Y91 Y92 Y95 P97 K110 A112 I114 S140 V141 S142 Y145 F248 C250 F301 S303 G304 E306 Q345 M349 R356 N373 L452 T453 K454 H475 S476 R483 I501 N502 L503 F526 P56981 31549070 EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8e A 2.61 BS02 NUC D 1 Y95 Y96 Q97 P98 V102 I109 D112 K114 E299 P345 G349 N352 G353 A356 R357 E525 G526 F527 Y94 Y95 Q96 P97 V101 I108 D111 K113 E298 P344 G348 N351 G352 A355 R356 E524 G525 F526 P56981 31549070 EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8e A 2.61 BS03 ADP A 1 Y11 E12 P13 Q14 Q17 T41 G42 G44 K45 F47 P414 R543 Y10 E11 P12 Q13 Q16 T40 G41 G43 K44 F46 P413 R542 P56981 31549070 EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8e B 2.61 BS01 NUC E 1 H65 N66 K67 V90 S91 Y92 Y93 Y96 K111 A113 I115 S141 S143 Y146 F249 S304 G305 I306 E307 Q346 M350 R357 N374 T454 K455 H476 S477 R484 I502 N503 L504 F527 H63 N64 K65 V88 S89 Y90 Y91 Y94 K109 A111 I113 S139 S141 Y144 F247 S302 G303 I304 E305 Q344 M348 R355 N372 T452 K453 H474 S475 R482 I500 N501 L502 F525 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI 6o8e B 2.61 BS02 NUC F 1 Y95 Q97 P98 V102 I109 D112 K114 M300 P345 G349 N352 G353 R357 E525 G526 F527 Y93 Q95 P96 V100 I107 D110 K112 M298 P343 G347 N350 G351 R355 E523 G524 F525 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI 6o8e B 2.61 BS03 ADP B 1 Y11 E12 Q14 Q17 G42 T43 G44 K45 P414 R543 Y9 E10 Q12 Q15 G40 T41 G42 K43 P412 R541 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI 6o8e B 2.61 BS04 MG B 1 N352 E380 N350 E378 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI 6o8f A 2.81 BS01 NUC C 1 H65 N66 K67 S91 Y92 Y93 Y96 K111 A113 K114 I115 S141 S143 Y146 F249 C251 S304 G305 E307 Q346 M350 R357 N374 T454 K455 H476 S477 R484 I502 N503 L504 H63 N64 K65 S89 Y90 Y91 Y94 K109 A111 K112 I113 S139 S141 Y144 F247 C249 S302 G303 E305 Q344 M348 R355 N372 T452 K453 H474 S475 R482 I500 N501 L502 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8f A 2.81 BS02 NUC D 1 Y95 Q97 P98 I109 D112 K114 P345 G349 N352 G353 A356 E525 G526 F527 Y93 Q95 P96 I107 D110 K112 P343 G347 N350 G351 A354 E523 G524 F525 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8f A 2.81 BS03 MG A 1 D331 N387 D329 N385 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8f B 2.81 BS02 NUC F 1 Y95 Q97 P98 V102 I109 K114 P345 G349 N352 A356 R357 E525 G526 F527 Y95 Q97 P98 V102 I109 K114 P344 G348 N351 A355 R356 E524 G525 F526 P56981 31549070 VEGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEAYVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFGDEIERIREVDALTGEVLGEREHVAIFPASHFVCREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI 6o8g A 2.64 BS01 NUC D 1 H65 N66 K67 C91 Y95 S141 S143 Y146 R289 Q346 M350 R357 K358 L361 F366 T454 K455 H476 S477 R484 I502 N503 L504 F527 H64 N65 K66 C90 Y94 S123 S125 Y128 R271 Q328 M332 R339 K340 L343 F348 T436 K437 H458 S459 R466 I484 N485 L486 F509 P56981 31549070 EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYYKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHG 6o8g A 2.64 BS02 NUC E 1 N116 Y292 S304 P345 G349 G353 R357 G526 F527 S530 R532 N98 Y274 S286 P327 G331 G335 R339 G508 F509 S512 R514 P56981 31549070 EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYYKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHG 6o8g A 2.64 BS03 ADP A 1 Y11 E12 Q14 Q17 G42 T43 G44 K45 F47 R543 Y10 E11 Q13 Q16 G41 T42 G43 K44 F46 R525 P56981 31549070 EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYYKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHG 6o8g B 2.64 BS01 NUC F 1 H65 N66 K67 C91 S141 Y146 R289 Q346 M350 R357 K358 T454 K455 H476 S477 R484 I502 N503 L504 F527 H63 N64 K65 C89 S118 Y123 R266 Q323 M327 R334 K335 T431 K432 H453 S454 R461 I479 N480 L481 F504 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKE 6o8g B 2.64 BS02 NUC G 1 P345 G349 G353 R357 E525 G526 F527 S530 R532 P322 G326 G330 R334 E502 G503 F504 S507 R509 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKE 6o8g B 2.64 BS03 ADP B 1 Y11 E12 Q14 Q17 T41 G42 T43 G44 K45 P414 R543 Y9 E10 Q12 Q15 T39 G40 T41 G42 K43 P391 R520 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKE 6o8g C 2.64 BS01 NUC H 1 H65 N66 K67 C91 S141 V142 Y146 R289 Q346 M350 R357 K358 L361 F366 K455 H476 S477 R484 I502 N503 L504 F527 H63 N64 K65 C89 S121 V122 Y126 R269 Q321 M325 R332 K333 L336 F341 K430 H451 S452 R459 I477 N478 L479 F502 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVP 6o8g C 2.64 BS02 NUC I 1 K114 Y292 P345 G349 M350 G353 R357 E525 G526 F527 K94 Y272 P320 G324 M325 G328 R332 E500 G501 F502 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVP 6o8g C 2.64 BS03 ADP C 1 Y11 E12 Q14 Q17 G42 G44 K45 F47 P414 R543 Y9 E10 Q12 Q15 G40 G42 K43 F45 P389 R518 P56981 31549070 GRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVP 6o8h A 2.39 BS01 NUC B 1 S143 R289 L361 F366 T454 K455 S477 R484 I502 N503 L504 S123 R269 L339 F344 T432 K433 S455 R462 I480 N481 L482 P56981 31549070 VEGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGALRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6o8h A 2.39 BS02 NUC C 1 P345 G349 N352 A356 A527 S530 R532 P323 G327 N330 A334 A505 S508 R510 P56981 31549070 VEGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISNVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFGDEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGALRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEIR 6oes A 3.06 BS01 NUC F 1 G603 K618 L794 H795 R848 G851 N852 R855 E959 Q962 K966 R969 G143 K158 L334 H335 R388 G391 N392 R395 E499 Q502 K506 R509 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes A 3.06 BS02 NUC J 1 D708 E709 K710 S721 H795 K823 K931 T933 N934 Y935 D248 E249 K250 S261 H335 K363 K471 T473 N474 Y475 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes A 3.06 BS03 NUC G 1 Y485 K489 P499 H501 S606 K608 H609 G610 A720 G722 S723 R773 M847 Q978 Y25 K29 P39 H41 S146 K148 H149 G150 A260 G262 S263 R313 M387 Q518 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes A 3.06 BS04 NUC L 1 K645 S648 E649 L650 N852 R855 P891 R894 S895 S896 E901 E959 K185 S188 E189 L190 N392 R395 P431 R434 S435 S436 E441 E499 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes A 3.06 BS05 NUC M 1 S477 C478 S479 Q480 K483 R504 M974 N975 A976 R977 Q978 K989 S17 C18 S19 Q20 K23 R44 M514 N515 A516 R517 Q518 K529 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes A 3.06 BS06 CA A 1 D600 G601 D140 G141 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes A 3.06 BS07 ZN A 1 C727 C730 H937 H942 C267 C270 H477 H482 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oes B 3.06 BS01 NUC F 1 A338 M339 A332 M333 P21784 MSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAIFSKDSCYLPPLRYPATCSYKKHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEPRYGHSIDVVYSRGKSMGVLFGGRSYMPSTQRTTEKWNSVADCLPHVFLIDFEFGCATSYILPELQDGLSFHVSIARNDTVYILGGHSLASNIRPANLYRIRVDLPLGTPAVNCTVLPGGISVSSAILTQTNNDEFVIVGGYQLENQKRMVCSLVSLGDNTIEISEMETPDWTSDIKHSKIWFGSNMGNGTIFLGIPGDNKQAMSEAFYFYTLRC 6oes B 3.06 BS02 NUC G 1 K38 R39 M339 K38 R39 M333 P21784 MSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAIFSKDSCYLPPLRYPATCSYKKHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEPRYGHSIDVVYSRGKSMGVLFGGRSYMPSTQRTTEKWNSVADCLPHVFLIDFEFGCATSYILPELQDGLSFHVSIARNDTVYILGGHSLASNIRPANLYRIRVDLPLGTPAVNCTVLPGGISVSSAILTQTNNDEFVIVGGYQLENQKRMVCSLVSLGDNTIEISEMETPDWTSDIKHSKIWFGSNMGNGTIFLGIPGDNKQAMSEAFYFYTLRC 6oes C 3.06 BS01 NUC F 1 Y485 K489 Q495 P499 H501 K608 H609 G610 A720 G722 S723 V724 R773 M847 R848 Q978 Y25 K29 Q35 P39 H41 K148 H149 G150 A260 G262 S263 V264 R313 M387 R388 Q518 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6oes C 3.06 BS02 NUC I 1 D708 E709 S721 R734 H795 T933 N934 Y935 D248 E249 S261 R274 H335 T473 N474 Y475 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6oes C 3.06 BS05 NUC M 1 K645 S648 L650 N852 R855 P891 R894 S896 E901 E959 K185 S188 L190 N392 R395 P431 R434 S436 E441 E499 3.1.-.-,2.3.2.27 P15919 GLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6oes D 3.06 BS02 NUC G 1 Q337 M339 Q331 M333 P21784 MSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAIFSKDSCYLPPLRYPATCSYKKHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEPRYGHSIDVVYSRGKSMGVLFGGRSYMPSTQRTTEKWNSVADCLPHVFLIDFEFGCATSYILPELQDGLSFHVSIARNDTVYILGGHSLASNIRPANLYRIRVDLPLGTPAVNCTVLPGGISVSSAILTQTNNDEFVIVGGYQLENQKRMVCSLVSLGDNTIEISEMETPDWTSDIKHSKIWFGSNMGNGTIFLGIPGDNKQAMSEAFYFYTLRCS 6oet A 3.40 BS01 NUC F 1 N443 G603 L794 H795 I798 R848 G851 N852 R855 E959 Q962 K966 R969 N53 G213 L404 H405 I408 R458 G461 N462 R465 E569 Q572 K576 R579 3.1.-.-,2.3.2.27 P15919 RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oet A 3.40 BS02 NUC I 1 E709 S721 R734 H795 K823 K931 I932 T933 N934 Y935 E319 S331 R344 H405 K433 K541 I542 T543 N544 Y545 3.1.-.-,2.3.2.27 P15919 RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oet A 3.40 BS03 NUC G 1 R391 R393 Q394 L399 R402 A403 H406 R407 Y485 K489 P499 H501 K608 H609 G610 A720 G722 S723 V724 R773 M847 Q978 R1 R3 Q4 L9 R12 A13 H16 R17 Y95 K99 P109 H111 K218 H219 G220 A330 G332 S333 V334 R383 M457 Q588 3.1.-.-,2.3.2.27 P15919 RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oet A 3.40 BS04 NUC L 1 R440 A441 H445 K645 S648 L650 N852 R855 P891 R894 S896 E901 E959 R50 A51 H55 K255 S258 L260 N462 R465 P501 R504 S506 E511 E569 3.1.-.-,2.3.2.27 P15919 RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oet A 3.40 BS05 NUC M 1 R391 R401 R409 S477 C478 S479 Q480 K483 R504 M974 N975 A976 R977 Q978 K989 R1 R11 R19 S87 C88 S89 Q90 K93 R114 M584 N585 A586 R587 Q588 K599 3.1.-.-,2.3.2.27 P15919 RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oet A 3.40 BS06 CA A 1 D600 G601 Q962 D210 G211 Q572 3.1.-.-,2.3.2.27 P15919 RPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA 6oet C 3.40 BS01 NUC F 1 K388 G389 G390 R391 R393 Q394 L399 T400 R402 A403 H406 R407 Y485 K489 H501 K608 H609 G610 A720 G722 S723 V724 M847 Q978 K4 G5 G6 R7 R9 Q10 L15 T16 R18 A19 H22 R23 Y101 K105 H117 K224 H225 G226 A336 G338 S339 V340 M463 Q594 3.1.-.-,2.3.2.27 P15919 HINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6oet C 3.40 BS03 NUC G 1 N443 G603 K618 L794 H795 I798 R848 N850 G851 N852 R855 E959 Q962 K966 R969 N59 G219 K234 L410 H411 I414 R464 N466 G467 N468 R471 E575 Q578 K582 R585 3.1.-.-,2.3.2.27 P15919 HINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6oet C 3.40 BS04 NUC L 1 N387 G389 G390 R391 P392 R401 R402 K405 K416 S477 C478 S479 Q480 K483 R504 M974 N975 A976 R977 Q978 K989 N3 G5 G6 R7 P8 R17 R18 K21 K32 S93 C94 S95 Q96 K99 R120 M590 N591 A592 R593 Q594 K605 3.1.-.-,2.3.2.27 P15919 HINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6oet C 3.40 BS05 NUC M 1 R440 N443 H445 K645 S648 N852 R855 P891 R894 S896 E901 E959 R56 N59 H61 K261 S264 N468 R471 P507 R510 S512 E517 E575 3.1.-.-,2.3.2.27 P15919 HINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN 6pjw A 2.40 BS01 AMP A 1 N38 F39 G40 M43 R56 M59 R60 Q71 D90 T91 H92 V95 G104 L105 R138 N37 F38 G39 M42 R55 M58 R59 Q70 D89 T90 H91 V94 G103 L104 R137 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw A 2.40 BS02 AMP A 2 G13 V14 G15 G16 T18 R131 D135 N175 R176 D177 G178 L179 L180 G12 V13 G14 G15 T17 R130 D134 N174 R175 D176 G177 L178 L179 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw A 2.40 BS03 MG A 1 T17 R140 T16 R139 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw B 2.40 BS02 AMP B 2 G13 V14 G15 T17 T18 R131 N175 R176 D177 G178 L179 L180 G12 V13 G14 T16 T17 R130 N174 R175 D176 G177 L178 L179 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw C 2.40 BS02 AMP C 2 G13 V14 G15 G16 T17 T18 R131 R140 N175 R176 D177 G178 L179 L180 G12 V13 G14 G15 T16 T17 R130 R139 N174 R175 D176 G177 L178 L179 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw D 2.40 BS02 AMP D 2 G13 G15 G16 T17 T18 R131 D135 N175 R176 D177 G178 L179 L180 G12 G14 G15 T16 T17 R130 D134 N174 R175 D176 G177 L178 L179 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pjw F 2.40 BS02 AMP F 2 P12 G13 G15 T17 T18 R131 R140 N175 R176 D177 G178 L179 L180 P11 G12 G14 T16 T17 R130 R139 N174 R175 D176 G177 L178 L179 2.7.4.3 P43408 KNKVVVVTGVPGVGGTTLTQKTIEKLKEEGIEYKMVNFGTVMFEVAKEEGLVEDRDQMRKLDPDTQKRIQKLAGRKIAEMAKESNVIVDTHSTVKTPKGYLAGLPIWVLEELNPDIIVIVETSSDEILMRRLGDATRNRDIELTSDIDEHQFMNRCAAMAYGVLTGATVKIIKNRDGLLDKAVEELISVLK 6pk0 A 1.75 BS01 HIW A 1 A69 S70 K73 I102 W105 S118 V120 L158 T209 G210 Y211 S244 L247 R250 A48 S49 K52 I81 W84 S97 V99 L137 T188 G189 Y190 S223 L226 R229 A0A482LRD5 FQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pk0 A 1.75 BS02 HIW A 2 S184 E185 R186 S163 E164 R165 A0A482LRD5 FQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pk0 B 1.75 BS01 HIW B 1 A69 S70 K73 I102 W105 Y117 S118 V120 L158 T209 G210 Y211 R250 A47 S48 K51 I80 W83 Y95 S96 V98 L136 T187 G188 Y189 R228 A0A482LRD5 QGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pk0 D 1.75 BS01 HIW D 1 A69 S70 K73 S118 V120 L158 T209 G210 Y211 L247 R250 A49 S50 K53 S98 V100 L138 T189 G190 Y191 L227 R230 A0A482LRD5 YFQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pnx A 2.20 BS01 ACP A 1 L478 E480 G481 F483 A506 V555 E556 Y557 A558 N562 L624 L23 E25 G26 F28 A51 V100 E101 Y102 A103 N107 L158 2.7.10.1 P22607 ELELPADPKWELSRARLTLGKPLGEGAFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDEVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTST 6pnx B 2.20 BS01 ACP B 1 L478 G479 G481 E556 Y557 A558 N622 L624 D635 L24 G25 G27 E102 Y103 A104 N160 L162 D173 2.7.10.1 P22607 SELELPADPKWELSRARLTLGKPLGEGAFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDEVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTS 6pqi A 2.05 BS01 CEF A 1 S70 I102 W105 S118 V120 T209 G210 Y211 S212 T213 R214 R250 S52 I84 W87 S100 V102 T191 G192 Y193 S194 T195 R196 R232 3.5.2.6 A0A482LRD5 NLYFQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pqi B 2.05 BS01 CEF B 1 A69 S70 I102 W105 S118 V120 L158 T209 G210 Y211 T213 R250 A49 S50 I82 W85 S98 V100 L138 T189 G190 Y191 T193 R230 3.5.2.6 A0A482LRD5 YFQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pqi D 2.05 BS01 CEF D 1 S70 W105 S118 V120 T209 G210 Y211 T213 R250 S49 W84 S97 V99 T188 G189 Y190 T192 R229 3.5.2.6 A0A482LRD5 FQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6prx A 3.25 BS01 PLP A 1 R99 R192 K202 Y207 E237 G239 T240 M241 N242 L266 G268 V269 V270 G312 T313 R92 R179 K189 Y194 E224 G226 T227 M228 N229 L253 G255 V256 V257 G299 T300 2.6.1.42 O15382 31929181 SSFKAADLQLEMTQKPHKKPGVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPRRALLFVILCPVGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVAPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 6prx B 3.25 BS01 PLP B 1 R192 K202 Y207 E237 T240 M241 N242 L266 G268 V269 V270 G312 T313 R185 K195 Y200 E230 T233 M234 N235 L259 G261 V262 V263 G305 T306 2.6.1.42 O15382 31929181 SSFKAADLQLEMTQKPHKKPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPRRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVAPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 6psg A 2.13 BS01 DGF A 1 A69 S70 I102 S118 V120 L158 T209 G210 Y211 R250 A51 S52 I84 S100 V102 L140 T191 G192 Y193 R232 3.5.2.6 A0A482LRD5 NLYFQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6psg D 2.13 BS01 DGF D 1 A69 S70 I102 W105 S118 V120 T209 G210 Y211 L247 R250 A48 S49 I81 W84 S97 V99 T188 G189 Y190 L226 R229 3.5.2.6 A0A482LRD5 FQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pt1 A 2.00 BS01 MER A 1 A69 S70 I102 W105 S118 V120 L158 K208 T209 G210 Y211 L247 R250 A51 S52 I84 W87 S100 V102 L140 K190 T191 G192 Y193 L229 R232 3.5.2.6 A0A482LRD5 NLYFQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pt1 B 2.00 BS01 MER B 1 A69 S70 W105 S118 V120 T209 G210 Y211 R250 A48 S49 W84 S97 V99 T188 G189 Y190 R229 3.5.2.6 A0A482LRD5 FQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pt5 A 2.30 BS01 1S7 A 1 S70 W105 S118 V120 L158 T209 G210 Y211 S212 T213 R214 R250 S50 W85 S98 V100 L138 T189 G190 Y191 S192 T193 R194 R230 3.5.2.6 A0A482LRD5 YFQGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6ptu A 2.00 BS01 ID1 A 1 A69 S70 S118 V120 L158 T209 G210 Y211 S244 L247 R250 A47 S48 S96 V98 L136 T187 G188 Y189 S222 L225 R228 3.5.2.6 A0A482LRD5 QGWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 6pvf A 1.69 BS01 FAD A 1 G14 G16 I17 V18 E37 K38 I45 G46 D47 C48 I49 R109 V131 V133 S165 D166 G167 R192 W256 G315 D316 A329 G10 G12 I13 V14 E33 K34 I41 G42 D43 C44 I45 R105 V127 V129 S161 D162 G163 R188 W252 G311 D312 A325 L0E4H0 31904957 GEEVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSNATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPNYLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGERQIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDPEASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLDVWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHWVSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLALHVAERIRYARASAVQLISHRVNEGWRNQDWDAYEPNEQNIASLPLETWIYGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV 6pvf A 1.69 BS02 MB5 A 1 Q52 I81 L96 V99 F219 V221 F243 A324 A325 G326 I395 A396 P399 L400 Q48 I77 L92 V95 F215 V217 F239 A320 A321 G322 I391 A392 P395 L396 L0E4H0 31904957 GEEVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSNATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPNYLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGERQIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDPEASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLDVWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHWVSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLALHVAERIRYARASAVQLISHRVNEGWRNQDWDAYEPNEQNIASLPLETWIYGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV 6pvh A 1.89 BS01 OZ4 A 1 V76 I81 L96 V99 N104 F219 V221 F243 I245 A324 A325 G326 I395 A396 P399 L400 V72 I77 L92 V95 N100 F215 V217 F239 I241 A320 A321 G322 I391 A392 P395 L396 L0E4H0 31904957 GEEVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSNATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPNYLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGERQIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDPEASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLDVWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHWVSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLALHVAERIRYARASAVQLISHRVNEGWRNQDWDAYEPNEQNIASLPLETWIYGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV 6pvh A 1.89 BS02 FAD A 1 G14 G16 I17 V18 E37 K38 I45 G46 D47 I49 R109 V131 V133 D166 G167 W256 G315 D316 A329 G10 G12 I13 V14 E33 K34 I41 G42 D43 I45 R105 V127 V129 D162 G163 W252 G311 D312 A325 L0E4H0 31904957 GEEVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSNATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPNYLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGERQIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDPEASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLDVWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHWVSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLALHVAERIRYARASAVQLISHRVNEGWRNQDWDAYEPNEQNIASLPLETWIYGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV 6pvi A 2.09 BS01 OZ7 A 1 Q52 V76 N104 Q228 A230 Q232 F243 I245 A324 S397 Q46 V70 N98 Q222 A224 Q226 F237 I239 A318 S387 L0E4H0 31904957 EVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSNATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPNYLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGERQIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDPEASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLDVWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHWVSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLALHVAERIRYARASAVQLISHRVNEGWRNQDWDAYENIASLPLETWIYGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV 6pvj A 1.25 BS02 OZA A 1 I81 L96 V99 C100 F219 V221 Q228 F243 A324 G326 I395 A396 P399 I77 L92 V95 C96 F215 V217 Q224 F239 A320 G322 I391 A392 P395 L0E4H0 31904957 GEEVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSNATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPNYLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGERQIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDPEASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLDVWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHWVSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLALHVAERIRYARASAVQLISHRVNEGWRNQDWDAYEPNEQNIASLPLETWIYGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV 6q09 A 1.75 BS01 FE A 1 H11 H45 E49 E109 H12 H46 E50 E110 A0A1V3WIE5 31913442 MVNAYEVLKEHHVVIKGLGRKISEAPVNSEERHALFDELLIELDIHFRIEDDLYYPALSAATKLIAVAHAEHRQVIDQLSVLLRTPQSEPGYEDEWNSFKTVLEAHADEEERDMIPAPPEVKITDAELEELGEKMAARMEQYRGSALYKLRTKGRAALVRSL 6q09 A 1.75 BS02 FE A 2 F46 E49 Y54 H71 H105 E109 F47 E50 Y55 H72 H106 E110 A0A1V3WIE5 31913442 MVNAYEVLKEHHVVIKGLGRKISEAPVNSEERHALFDELLIELDIHFRIEDDLYYPALSAATKLIAVAHAEHRQVIDQLSVLLRTPQSEPGYEDEWNSFKTVLEAHADEEERDMIPAPPEVKITDAELEELGEKMAARMEQYRGSALYKLRTKGRAALVRSL 6q2p A 1.45 BS01 SF4 A 1 C84 Y86 C88 C91 G126 N158 R194 C15 Y17 C19 C22 G57 N89 R125 Q8CBB9 31917549 RTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGADALRAAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKL 6q2p A 1.45 BS02 SAH A 1 F90 F92 S124 G125 G126 E127 V156 S157 N158 S180 R194 N222 V224 F249 Q250 C251 L252 N258 M298 F21 F23 S55 G56 G57 E58 V87 S88 N89 S111 R125 N153 V155 F180 Q181 C182 L183 N189 M229 Q8CBB9 31917549 RTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGADALRAAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKL 6q2p A 1.45 BS03 CTP A 1 N77 H79 F92 K120 N122 S124 K220 N222 R245 K247 F249 M298 K299 Y302 I304 C314 K319 R347 Y351 N8 H10 F23 K51 N53 S55 K151 N153 R176 K178 F180 M229 K230 Y233 I235 C245 K250 R278 Y282 Q8CBB9 31917549 RTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGADALRAAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKL 6q2p B 1.45 BS02 SAH B 1 F90 C91 F92 S124 G125 G126 E127 V156 S157 N158 S180 R194 N222 V224 F249 C251 L252 N258 M298 F21 C22 F23 S55 G56 G57 E58 V87 S88 N89 S111 R125 N153 V155 F180 C182 L183 N189 M229 Q8CBB9 31917549 RTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGADALRAAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW 6q2q A 1.89 BS01 SF4 A 1 C84 Y86 C88 C91 G126 N158 R194 R265 C14 Y16 C18 C21 G56 N88 R124 R195 Q8CBB9 31917549 TTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGADALRAAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKL 6q2q A 1.89 BS03 UTP A 1 N77 H79 F92 K120 N122 S124 K220 N222 R245 K247 F249 L252 Y302 I304 K319 R347 Y351 N7 H9 F22 K50 N52 S54 K150 N152 R175 K177 F179 L182 Y232 I234 K249 R277 Y281 Q8CBB9 31917549 TTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGADALRAAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKL 6qnx A 2.70 BS01 III C 1 Y297 R298 D326 L329 K330 Y331 W334 L366 F367 R370 Y213 R214 D242 L245 K246 Y247 W250 L282 F283 R286 Q8N3U4 31905366 ENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFLKTREAIAMLHKDGIEFAFKEPNPQGESPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREVWLPLMSYRNSL 6qnx B 2.70 BS01 III C 1 S334 I337 R338 L341 S14 I17 R18 L21 O60216 31905366 KRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLT 6r1m A 1.50 BS01 SSA A 1 T237 E239 R268 E270 I282 R283 M284 F287 K289 E291 E355 I356 S357 S358 N389 S391 A394 R397 T237 E239 R268 E270 I282 R283 M284 F287 K289 E291 E355 I356 S357 S358 N386 S388 A391 R394 6.1.1.11 A0A1X3JK72 31626547 MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG 6r1n A 2.03 BS01 SSA A 1 T231 E233 R262 E264 I276 R277 L278 F281 K283 E285 E349 I350 S351 S352 N383 G384 S385 A388 R391 T229 E231 R260 E262 I269 R270 L271 F274 K276 E278 E342 I343 S344 S345 N376 G377 S378 A381 R384 6.1.1.11 X5DWM7 31626547 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEADTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPV 6r1o A 2.60 BS01 JPE A 1 T237 E239 R268 E270 L281 I282 R283 M284 F287 K289 E291 E355 I356 S357 S358 N389 S391 A394 G396 R397 T237 E239 R268 E270 L276 I277 R278 M279 F282 K284 E286 E350 I351 S352 S353 N382 S384 A387 G389 R390 6.1.1.11 A0A1X3JK72 31626547 MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIGE 6r1o A 2.60 BS02 JPE A 2 S191 N193 L245 E249 I251 D255 I258 M260 S191 N193 L245 E249 I251 D255 I258 M260 6.1.1.11 A0A1X3JK72 31626547 MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIGE 6r1o A 2.60 BS03 JPE A 3 E131 F132 D133 F134 E135 V136 E131 F132 D133 F134 E135 V136 6.1.1.11 A0A1X3JK72 31626547 MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIGE 6r1v A BS01 JPT A 1 A60 G61 I124 C126 W136 R139 A60 G61 I124 C126 W136 R139 3.4.22.70 Q2FV99 31724850 MQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVEVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK 6rua B 2.75 BS02 KJT B 1 G117 Q119 T120 S198 W231 L286 S287 F329 Y332 F398 W430 M437 H438 Y440 G114 Q116 T117 S195 W228 L283 S284 F326 Y329 F395 W427 M434 H435 Y437 3.1.1.8 P06276 31914836 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 6ryk A 1.70 BS01 CTP A 1 R311 L319 D322 I323 G327 L329 F330 G347 F348 R349 R350 R23 L31 D34 I35 G39 L41 F42 G59 F60 R61 R62 Q1D3H3 31835030 SGRVTTVLLPLEKLQDESAFKLRPEGDVSGLATDIARLGQLFPVDVRPAGEDRYQLVCGFRRVAALRFLKRDAVQARIHLRLSDEDALVMSLAEAIHATPVGPEVLEAKRDELEAQGRLSAAVRDMLEKALAT 6ryk A 1.70 BS02 CTP B 1 E382 H385 A386 T387 E94 H97 A98 T99 Q1D3H3 31835030 SGRVTTVLLPLEKLQDESAFKLRPEGDVSGLATDIARLGQLFPVDVRPAGEDRYQLVCGFRRVAALRFLKRDAVQARIHLRLSDEDALVMSLAEAIHATPVGPEVLEAKRDELEAQGRLSAAVRDMLEKALAT 6s0y A 1.81 BS01 III C 1 F37 G44 R45 Q46 G47 V48 S49 C50 I59 Y60 A61 V103 E104 G105 C106 G107 Y108 W113 F34 G41 R42 Q43 G44 V45 S46 C47 I56 Y57 A58 V100 E101 G102 C103 G104 Y105 W110 31921179 VQLQESGGGLVQTGGSLRLSCAFSGFDDYVIGWFRQAPGKGRQGVSCIRLSGGGTIYADSAKGRFTVSADNAKKTVYLQMTRLKPEDTAVYYCGAERYNVEGCGYDVAYWGKGTQVTVSS 6s9k A 1.60 BS01 III B 1 N43 V47 R57 R132 Y133 P170 L177 N178 V181 D214 D218 L221 I222 L225 N229 L232 W233 N42 V46 R56 R126 Y127 P164 L171 N172 V175 D208 D212 L215 I216 L219 N223 L226 W227 P61981 VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 6s9k A 1.60 BS02 CFH A 1 E15 N43 L44 V47 E14 N42 L43 V46 P61981 VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 6s9k A 1.60 BS03 CFH A 2 L221 L225 D228 L215 L219 D222 P61981 VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 6sad A 2.75 BS01 III C 1 K50 R57 R61 R132 Y133 L177 N178 V181 E185 N229 K49 R56 R60 R131 Y132 L176 N177 V180 E184 N228 P61981 VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 6sad B 2.75 BS01 III C 2 E15 Q16 V47 K50 R57 R61 R132 Y133 L177 N178 V181 I222 N229 E14 Q15 V46 K49 R56 R60 R131 Y132 L176 N177 V180 I221 N228 P61981 VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWT 6sp7 A 1.80 BS03 K9B A 1 F61 Y67 W87 H116 H118 D120 E149 H196 C221 G232 N233 D236 H263 F31 Y36 W56 H83 H85 D87 E115 H148 C167 G178 N179 D182 H209 S5M6K4 31765155 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 6sp7 E 1.80 BS03 K9B E 1 W87 H116 H118 D120 E149 H196 C221 G232 N233 D236 H263 W56 H83 H85 D87 E115 H148 C167 G178 N179 D182 H209 S5M6K4 31765155 EYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTN 6szg A 1.84 BS01 M2K A 1 M27 D28 G29 N30 N31 H45 A71 N76 R79 L87 M10 D11 G12 N13 N14 H28 A54 N59 R62 L70 2.5.1.31 V5VCK8 31929185 HLPQHVAIIMDGNNRFAKKNQMQKGDGHREGKNVLDPIVEHCVKTGVRALTVFAFSSENWNRPQYEVDLLMKLLEETIHEQIPRMKKFNIALRFIGDRSRLPSHLVALMEDAEQQTAHHDAMTLTIAVSYGGMWDIANAAKQVAQAVSRGEIDADQINVDLFEKYVSLNDLPAVDLLIRTGGDFRISNFLLWQAAYAELYFTDTLWPEFTVEEFDHALNVFS 6szg A 1.84 BS02 M2E A 1 M27 K49 L52 A71 L87 L90 L91 T94 Q98 L141 I143 M10 K32 L35 A54 L70 L73 L74 T77 Q81 L124 I126 2.5.1.31 V5VCK8 31929185 HLPQHVAIIMDGNNRFAKKNQMQKGDGHREGKNVLDPIVEHCVKTGVRALTVFAFSSENWNRPQYEVDLLMKLLEETIHEQIPRMKKFNIALRFIGDRSRLPSHLVALMEDAEQQTAHHDAMTLTIAVSYGGMWDIANAAKQVAQAVSRGEIDADQINVDLFEKYVSLNDLPAVDLLIRTGGDFRISNFLLWQAAYAELYFTDTLWPEFTVEEFDHALNVFS 6szg B 1.84 BS01 CA B 1 D170 D172 D139 D141 2.5.1.31 V5VCK8 31929185 SEEYHLPQHVAIIMDGNNNVLDPIVEHCVKTGVRALTVFAFSSENWNRPQYEVDLLMKLLEETIHEQIPRMKKFNIALRFIGDRSRLPSHLVALMEDAEQQTAHHDAMTLTIAVSYGGMWDIANAAKQVAQAVSRGEIDADQINVDLFEKYVSLNDLPAVDLLIRTGGDFRISNFLLWQAAYAELYFTDTLWPEFTVEEFDHALNVFSGRERR 6szh B 1.65 BS02 M2H B 1 I26 L194 I203 S204 F206 A211 L216 I13 L163 I172 S173 F175 A180 L185 2.5.1.31 V5VCK8 31929185 SEEYHLPQHVAIIMDGNNNVLDPIVEHCVKTGVRALTVFAFSSENWNRPQYEVDLLMKLLEETIHEQIPRMKKFNIALRFIGDRSRLPSHLVALMEDAEQQTAHHDAMTLTIAVSYGGMWDIANAAKQVAQAVSRGEIDADQINVDLFEKYVSLNDLPAVDLLIRTGGDFRISNFLLWQAAYAELYFTDTLWPEFTVEEFDHALNVFSGRERR 6td0 A 0.99 BS01 4D6 A 1 C69 S70 K73 W105 S130 N132 L167 N170 T235 G236 T237 C238 G239 C46 S47 K50 W82 S107 N109 L144 N147 T212 G213 T214 C215 G216 3.5.2.6 Q9F663 HMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVNG 6td1 A 1.20 BS01 KJK A 1 C69 S70 K73 W105 S130 N132 L167 T235 G236 T237 G239 C46 S47 K50 W82 S107 N109 L144 T212 G213 T214 G216 3.5.2.6 Q9F663 HMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVNG 6tfq A 2.05 BS01 GLC A 1 E41 N233 N234 E12 N204 N205 O50271 31922182 AKTELSMGVASEDVTTLDPHFATTTSDRTLVSYIYGALVRFAPGSANPSSIEADLAESWESNADQLVWTFKLRPDVKWQGGYGNVTADDVVFSLDKARDPKRSAFSGDYAAIQKVEAVDAKTVRITLTRRVPSLLALLSNFSGGFIIPKKAFKERGDDFKRRPVGFGPFQVESIQPGQSVTLTANAEYFRGKPKLSKISYRFLNNEAARDLAFESGELDVEQGNQDQRWLQRLTANPENVVDTIEPAELNLLHINITKPPFNDIRVRQALAHTVNAAQIAKYRGERVNRAVPSVIPSNNLGFDPDAGVLNYDPAQSKKLLAEAGFPNGVTVTMVASQLPGLESLAQLIQAQVAEGGFTLNLQPVEHAAWHQMIRKDLSPIVLYGAARFPIADYYLTQFYHSASEIGKPTQVVNFSHCNVADKQIEAARTETDPNKQIELWKEAQKLIVSNVCAIPLTENLGTWARKNKLGWGFELKGSMPSAPLITEQTYFKD 6tfq A 2.05 BS02 N72 A 1 T52 T53 T54 R57 Q254 E277 N279 R312 L367 G369 L370 H395 H399 Y412 G413 R416 N488 T23 T24 T25 R28 Q225 E248 N250 R283 L338 G340 L341 H366 H370 Y383 G384 R387 N459 O50271 31922182 AKTELSMGVASEDVTTLDPHFATTTSDRTLVSYIYGALVRFAPGSANPSSIEADLAESWESNADQLVWTFKLRPDVKWQGGYGNVTADDVVFSLDKARDPKRSAFSGDYAAIQKVEAVDAKTVRITLTRRVPSLLALLSNFSGGFIIPKKAFKERGDDFKRRPVGFGPFQVESIQPGQSVTLTANAEYFRGKPKLSKISYRFLNNEAARDLAFESGELDVEQGNQDQRWLQRLTANPENVVDTIEPAELNLLHINITKPPFNDIRVRQALAHTVNAAQIAKYRGERVNRAVPSVIPSNNLGFDPDAGVLNYDPAQSKKLLAEAGFPNGVTVTMVASQLPGLESLAQLIQAQVAEGGFTLNLQPVEHAAWHQMIRKDLSPIVLYGAARFPIADYYLTQFYHSASEIGKPTQVVNFSHCNVADKQIEAARTETDPNKQIELWKEAQKLIVSNVCAIPLTENLGTWARKNKLGWGFELKGSMPSAPLITEQTYFKD 6tfx A 1.56 BS02 MG A 1 S40 T53 H395 S11 T24 H366 O50271 31922182 AKTELSMGVASEDVTTLDPHFATTTSDRTLVSYIYGALVRFAPGSANPSSIEADLAESWESNADQLVWTFKLRPDVKWQGGYGNVTADDVVFSLDKARDPKRSAFSGDYAAIQKVEAVDAKTVRITLTRRVPSLLALLSNFSGGFIIPKKAFKERGDDFKRRPVGFGPFQVESIQPGQSVTLTANAEYFRGKPKLSKISYRFLNNEAARDLAFESGELDVEQGNQDQRWLQRLTANPENVVDTIEPAELNLLHINITKPPFNDIRVRQALAHTVNAAQIAKYRGERVNRAVPSVIPSNNLGFDPDAGVLNYDPAQSKKLLAEAGFPNGVTVTMVASQLPGLESLAQLIQAQVAEGGFTLNLQPVEHAAWHQMIRKDLSPIVLYGAARFPIADYYLTQFYHSASEIGKPTQVVNFSHCNVADKQIEAARTETDPNKQIELWKEAQKLIVSNVCAIPLTENLGTWARKNKLGWGFELKGSMPSAPLITEQTYFKD 6tfx A 1.56 BS03 MG A 2 C446 V448 C481 C417 V419 C452 O50271 31922182 AKTELSMGVASEDVTTLDPHFATTTSDRTLVSYIYGALVRFAPGSANPSSIEADLAESWESNADQLVWTFKLRPDVKWQGGYGNVTADDVVFSLDKARDPKRSAFSGDYAAIQKVEAVDAKTVRITLTRRVPSLLALLSNFSGGFIIPKKAFKERGDDFKRRPVGFGPFQVESIQPGQSVTLTANAEYFRGKPKLSKISYRFLNNEAARDLAFESGELDVEQGNQDQRWLQRLTANPENVVDTIEPAELNLLHINITKPPFNDIRVRQALAHTVNAAQIAKYRGERVNRAVPSVIPSNNLGFDPDAGVLNYDPAQSKKLLAEAGFPNGVTVTMVASQLPGLESLAQLIQAQVAEGGFTLNLQPVEHAAWHQMIRKDLSPIVLYGAARFPIADYYLTQFYHSASEIGKPTQVVNFSHCNVADKQIEAARTETDPNKQIELWKEAQKLIVSNVCAIPLTENLGTWARKNKLGWGFELKGSMPSAPLITEQTYFKD 6tfx B 1.56 BS03 MG B 2 G501 Y519 G472 Y490 O50271 31922182 AKTELSMGVASEDVTTLDPHFATTTSDRTLVSYIYGALVRFAPGSANPSSIEADLAESWESNADQLVWTFKLRPDVKWQGGYGNVTADDVVFSLDKARDPKRSAFSGDYAAIQKVEAVDAKTVRITLTRRVPSLLALLSNFSGGFIIPKKAFKERGDDFKRRPVGFGPFQVESIQPGQSVTLTANAEYFRGKPKLSKISYRFLNNEAARDLAFESGELDVEQGNQDQRWLQRLTANPENVVDTIEPAELNLLHINITKPPFNDIRVRQALAHTVNAAQIAKYRGERVNRAVPSVIPSNNLGFDPDAGVLNYDPAQSKKLLAEAGFPNGVTVTMVASQLPGLESLAQLIQAQVAEGGFTLNLQPVEHAAWHQMIRKDLSPIVLYGAARFPIADYYLTQFYHSASEIGKPTQVVNFSHCNVADKQIEAARTETDPNKQIELWKEAQKLIVSNVCAIPLTENLGTWARKNKLGWGFELKGSMPSAPLITEQTYFKDH 6tg2 A 2.21 BS01 N72 A 1 S37 W41 Q67 Q87 I88 G89 D92 S128 Y130 W165 W235 R238 D261 T297 S9 W13 Q39 Q59 I60 G61 D64 S100 Y102 W137 W207 R210 D233 T269 Q44384 31922182 HMDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLSR 6tg2 A 2.21 BS02 CA A 1 G40 A218 A221 R238 G12 A190 A193 R210 Q44384 31922182 HMDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLSR 6tg2 A 2.21 BS03 CA A 2 S330 V331 D332 S302 V303 D304 Q44384 31922182 HMDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLSR 6tg2 A 2.21 BS04 CA A 3 S37 Q67 S216 G217 W235 R238 S9 Q39 S188 G189 W207 R210 Q44384 31922182 HMDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLSR 6tg2 B 2.21 BS02 CA B 1 G237 Q240 G241 F295 A296 G209 Q212 G213 F267 A268 Q44384 31922182 HMDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLS 6tg2 C 2.21 BS01 N72 C 1 S37 W41 Q67 Q87 I88 G89 D92 S128 Y130 W235 R238 D261 F295 T297 S7 W11 Q37 Q57 I58 G59 D62 S98 Y100 W205 R208 D231 F265 T267 Q44384 31922182 DVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLSRHH 6tg2 D 2.21 BS02 CA D 1 E313 K314 E284 K285 Q44384 31922182 MDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRL 6tg3 A 1.85 BS01 N7T A 1 S37 W41 F66 Q67 Q87 S128 Y130 W235 R238 D261 T297 S10 W14 F39 Q40 Q60 S101 Y103 W208 R211 D234 T270 Q44384 31922182 SHMDVVIASSGGGWQEAQDKALWAPAAKALNITYTQDTFQNWAEARAQVESGSVTWDIIQIGIADEPQAKAAGVLEKLDPDIVNKADFPPGSVTDSFVANSNYSTLIAWNKKTYGDNGPKSMADFFDVKKFPGKRALWNQPIGMIEAAALALGTPRDKVYEFLSTEEGRKAAIAKLTELAPSVSVWWESGAQAAQLIKDGEVDMIITWGGRVQGAINDGANFAYTFNDAQLGTDGYAIVKGAPHRDAAMRFLKEMSKAEYQKDLPNSFATAPANMKAYDLAKYTPEKMATMASAPENVAVQYSVDPNFWAKHAKWASEAYDNVRLS 6tkz C 2.64 BS01 GDP C 1 G12 A13 V14 G15 K16 T17 C18 Q116 D118 L119 A159 G11 A12 V13 G14 K15 T16 C17 Q115 D117 L118 A158 3.6.5.2 P60953 QTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 6tkz D 2.64 BS01 GDP D 1 D11 G12 A13 V14 G15 K16 T17 C18 Q116 D118 S158 A159 L160 D11 G12 A13 V14 G15 K16 T17 C18 Q116 D118 S158 A159 L160 3.6.5.2 P60953 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 6tu9 A 1.94 BS01 0LI A 1 A504 K506 E523 L526 M527 V536 F552 E553 Y554 I555 V612 H613 K614 L622 I631 S632 D633 A45 K47 E64 L67 M68 V77 F93 E94 Y95 I96 V134 H135 K136 L144 I153 S154 D155 Q01973 KPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWMEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSW 6tu9 B 1.94 BS01 0LI B 1 L479 I487 A504 K506 E523 M527 L530 V536 F552 E553 Y554 I555 L606 V612 H613 L622 I631 S632 D633 L15 I23 A36 K38 E54 M58 L61 V67 F83 E84 Y85 I86 L118 V124 H125 L134 I143 S144 D145 Q01973 AKELPLSAVRFMEELGECAFGKIYKGHLYLHAQLVAIKTLKYNNPQQWMEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLIYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWE 6tyj A 1.60 BS01 ZN A 1 H11 H45 E49 H105 E109 H12 H46 E50 H106 E110 A0A1V3WIE5 MVNAYEVLKEHHVVIKGLGRKISEAPVNSEERHALFDELLIELDIHFRIEDDLYYPALSAATKLIAVAHAEHRQVIDQLSVLLRTPQSEPGYEDEWNSFKTVLEAHADEEERDMIPAPPEVKITDAELEELGEKMAARMEQYRGSALYKLRTKGRAALVRSL 6tyj A 1.60 BS02 ZN A 2 E49 Y54 H71 H105 E50 Y55 H72 H106 A0A1V3WIE5 MVNAYEVLKEHHVVIKGLGRKISEAPVNSEERHALFDELLIELDIHFRIEDDLYYPALSAATKLIAVAHAEHRQVIDQLSVLLRTPQSEPGYEDEWNSFKTVLEAHADEEERDMIPAPPEVKITDAELEELGEKMAARMEQYRGSALYKLRTKGRAALVRSL 6tyj A 1.60 BS03 ZN A 3 D50 H71 D51 H72 A0A1V3WIE5 MVNAYEVLKEHHVVIKGLGRKISEAPVNSEERHALFDELLIELDIHFRIEDDLYYPALSAATKLIAVAHAEHRQVIDQLSVLLRTPQSEPGYEDEWNSFKTVLEAHADEEERDMIPAPPEVKITDAELEELGEKMAARMEQYRGSALYKLRTKGRAALVRSL 6tyj A 1.60 BS04 ZN A 4 L34 E37 L35 E38 A0A1V3WIE5 MVNAYEVLKEHHVVIKGLGRKISEAPVNSEERHALFDELLIELDIHFRIEDDLYYPALSAATKLIAVAHAEHRQVIDQLSVLLRTPQSEPGYEDEWNSFKTVLEAHADEEERDMIPAPPEVKITDAELEELGEKMAARMEQYRGSALYKLRTKGRAALVRSL 6u1x A 3.00 BS01 III P 1 E1979 D1981 P2051 F2052 R2074 I2083 N2084 R2086 E1929 D1931 P2001 F2002 R2024 I2033 N2034 R2036 2.7.7.48,2.1.1.56,2.7.7.88,2.1.1.296 P03523 31914397 NHADYNLNSPLISDDIDNLIRKFNSLPIPSMWDSKNWDGVLEMLTSCQANPISTSQMHKWMGSWLMSDNHDASQGYSFLHEVDKEAEITFDVVETFIRGWGNKPIEYIKKERWTDSFKILAYLCQKFLDLHKLTLILNAVSEVELLNLARTFKGKVRRSSHGTNICRIRVPSLGPTFISEGWAYFKKLDILMDRNFLLMVKDVIIGRMQTVLSMVCRIDNLFSEQDIFSLLNIYRIGDKIVERQGNFSYDLIKMVEPICNLKLMKLARESRPLVPQFPHFENHIKTSVDEGAKIDRGIRFLHDQIMSVKTVDLTLVIYGSFRHWGHPFIDYYTGLEKLHSQVTMKKDIDVSYAKALASDLARIVLFQQFNDHKKWFVNGDLLPHDHPFKSHVKENTWPTAAQVQDFGDKWHELPLIKCFEIPDLLDPSIIYSDKSHSMNRSEVLKHVRMNPNTPIPSKKVLQTMLDTKATNWKEFLKEIDEKGLDDDDLIIGLKGKERELKLAGRFFSLMSWKLREYFVITEYLIKTHFVPMFKGLTMADDLTAVIKKMLDSSSGQGLKSYEAICIANHIDYEKWNNHQRKLSNGPVFRVMGQFLGYPSLIERTHEFFEKSLIYYNGRPDLMRVHNNTLINSTSQRVCWQGQEGGLEGLRQKGWTILNLLVIQREAKIRNTAVKVLAQGDNQVICTQYKTKKSRNVVELQGALNQMVSNNEKIMTAIKIGTGKLGLLINDDETMQSADYLNYGKIPIFRGVIRGLETKRWSRVTCVTNDQIPTCANIMSSVSTNALTVAHFAENPINAMIQYNYFGTFARLLLMMHDPALRQSLYEVQDKIPGLHSSTFKYAMLYLDPSIGGVSGMSLSRFLIRAFPDPVTESLSFWRFIHVHARSEHLKEMSAVFGNPEIAKFRITHIDKLVEDPTSLNIAMGMSPANLLKTEVKKCLIESRQTIRNQVIKDATIYLYHEEDRLRSFLWSINPLFPRFLSEFKSGTFLGVADGLISLFQNSRTIRNSFKKKYHRELDDLIVRSEVSSLTHLGKLHLRRGSCKMWTCSATHADTLRYKSWGRTVIGTTVPHPLEMLGPQHRKETPCAPCNTSGFNYVSVHCPDGIHDVFSSRGPLPAYLGSKTSESTSILQPWERESKVPLIKRATRLRDAISWFVEPDSKLAMTILSNIHSLTGEEHGFKRTGSALHRFSTSRMSHGGFASQSTAALTRLMATTDTMRDLGDQNFDFLFQATLLYAQITTTVARDGWITSCTDHYHIACKSCLRPIEEITLDSSMDYTPPDVSHVLKTWRNGEIKQIYPLEGNWKNLAPAEQSYQVGRCIGFLYGDLAYRKSTHAEDSSLFPLSIQGRIRGRGFLKGLLDGLMRASCCQVIHRRSLAHLKRPANAVYGGLIYLIDKLSVSPPFLSLTRSGPIRDELETIPHKIPTSYPTSNRDMGVIVRNYFKYQCRLIEKGKYRSHYSQLWLFSDVLSIDFIGPFSISTTLLQILYKPFLSGKDKNELRELANLSSLLRSGEGWEDIHVKFFTKDILLCPEEIRHACKFGIAKMSYPPWGRESRGTITTIPVYYTTTPYPKMLEMPPRIQNPLLSGIRLGQLPTGAHYKIRSILHGMGIHYRDFLSCGDGSGGMTAALLRENVHSRGIFNSLLELSGSVMRGASPEPPSALETLGGDKSRCVNGETCWEYPSDLCDPRTWDYFLRLKAGLGLQIDLIVMDMEVRDSSTSLKIETNVRNYVHRILDEQGVLIYKTYGTYICESEKNAVTILGPMFKTVDLVQTEFSSSQTSEVYMVCKGLKKLIDEPNPDWSSINESWKNLYAFQSSEQEFARAKKVSTYFTLTGIPSQFIPDPFVNIETMLQIFGVPTGVSHAAALKSSDRPADLLTISLFYMAIISYYNINHIRVGPIPPNPPSDGIAQNVGIAITGISFWLSLMEKDIPLYQQCLAVIQQSFPIRWEAVSVKGGYKQKWSTRGDGLPKDTRISDSLAPIGNWIRSLELVRNQVRLNPFNEILFNQLCRTVDNHLKWSNLRRNTGMIEWINRRISKEDRSILMLKSDLHEENSWRD 6u1x A 3.00 BS02 III P 2 K701 N704 Q739 N743 S1957 K2022 I2094 M2096 L2097 K2098 S2099 D2100 L2101 K667 N670 Q705 N709 S1907 K1972 I2044 M2046 L2047 K2048 S2049 D2050 L2051 2.7.7.48,2.1.1.56,2.7.7.88,2.1.1.296 P03523 31914397 NHADYNLNSPLISDDIDNLIRKFNSLPIPSMWDSKNWDGVLEMLTSCQANPISTSQMHKWMGSWLMSDNHDASQGYSFLHEVDKEAEITFDVVETFIRGWGNKPIEYIKKERWTDSFKILAYLCQKFLDLHKLTLILNAVSEVELLNLARTFKGKVRRSSHGTNICRIRVPSLGPTFISEGWAYFKKLDILMDRNFLLMVKDVIIGRMQTVLSMVCRIDNLFSEQDIFSLLNIYRIGDKIVERQGNFSYDLIKMVEPICNLKLMKLARESRPLVPQFPHFENHIKTSVDEGAKIDRGIRFLHDQIMSVKTVDLTLVIYGSFRHWGHPFIDYYTGLEKLHSQVTMKKDIDVSYAKALASDLARIVLFQQFNDHKKWFVNGDLLPHDHPFKSHVKENTWPTAAQVQDFGDKWHELPLIKCFEIPDLLDPSIIYSDKSHSMNRSEVLKHVRMNPNTPIPSKKVLQTMLDTKATNWKEFLKEIDEKGLDDDDLIIGLKGKERELKLAGRFFSLMSWKLREYFVITEYLIKTHFVPMFKGLTMADDLTAVIKKMLDSSSGQGLKSYEAICIANHIDYEKWNNHQRKLSNGPVFRVMGQFLGYPSLIERTHEFFEKSLIYYNGRPDLMRVHNNTLINSTSQRVCWQGQEGGLEGLRQKGWTILNLLVIQREAKIRNTAVKVLAQGDNQVICTQYKTKKSRNVVELQGALNQMVSNNEKIMTAIKIGTGKLGLLINDDETMQSADYLNYGKIPIFRGVIRGLETKRWSRVTCVTNDQIPTCANIMSSVSTNALTVAHFAENPINAMIQYNYFGTFARLLLMMHDPALRQSLYEVQDKIPGLHSSTFKYAMLYLDPSIGGVSGMSLSRFLIRAFPDPVTESLSFWRFIHVHARSEHLKEMSAVFGNPEIAKFRITHIDKLVEDPTSLNIAMGMSPANLLKTEVKKCLIESRQTIRNQVIKDATIYLYHEEDRLRSFLWSINPLFPRFLSEFKSGTFLGVADGLISLFQNSRTIRNSFKKKYHRELDDLIVRSEVSSLTHLGKLHLRRGSCKMWTCSATHADTLRYKSWGRTVIGTTVPHPLEMLGPQHRKETPCAPCNTSGFNYVSVHCPDGIHDVFSSRGPLPAYLGSKTSESTSILQPWERESKVPLIKRATRLRDAISWFVEPDSKLAMTILSNIHSLTGEEHGFKRTGSALHRFSTSRMSHGGFASQSTAALTRLMATTDTMRDLGDQNFDFLFQATLLYAQITTTVARDGWITSCTDHYHIACKSCLRPIEEITLDSSMDYTPPDVSHVLKTWRNGEIKQIYPLEGNWKNLAPAEQSYQVGRCIGFLYGDLAYRKSTHAEDSSLFPLSIQGRIRGRGFLKGLLDGLMRASCCQVIHRRSLAHLKRPANAVYGGLIYLIDKLSVSPPFLSLTRSGPIRDELETIPHKIPTSYPTSNRDMGVIVRNYFKYQCRLIEKGKYRSHYSQLWLFSDVLSIDFIGPFSISTTLLQILYKPFLSGKDKNELRELANLSSLLRSGEGWEDIHVKFFTKDILLCPEEIRHACKFGIAKMSYPPWGRESRGTITTIPVYYTTTPYPKMLEMPPRIQNPLLSGIRLGQLPTGAHYKIRSILHGMGIHYRDFLSCGDGSGGMTAALLRENVHSRGIFNSLLELSGSVMRGASPEPPSALETLGGDKSRCVNGETCWEYPSDLCDPRTWDYFLRLKAGLGLQIDLIVMDMEVRDSSTSLKIETNVRNYVHRILDEQGVLIYKTYGTYICESEKNAVTILGPMFKTVDLVQTEFSSSQTSEVYMVCKGLKKLIDEPNPDWSSINESWKNLYAFQSSEQEFARAKKVSTYFTLTGIPSQFIPDPFVNIETMLQIFGVPTGVSHAAALKSSDRPADLLTISLFYMAIISYYNINHIRVGPIPPNPPSDGIAQNVGIAITGISFWLSLMEKDIPLYQQCLAVIQQSFPIRWEAVSVKGGYKQKWSTRGDGLPKDTRISDSLAPIGNWIRSLELVRNQVRLNPFNEILFNQLCRTVDNHLKWSNLRRNTGMIEWINRRISKEDRSILMLKSDLHEENSWRD 6u1x A 3.00 BS03 III P 3 Y1375 R1419 R1420 A1429 N1430 A1431 Y1433 G1434 I1437 Y1438 E1496 K1497 G1498 Y1533 P1535 P1909 T1910 G1911 Y1330 R1374 R1375 A1384 N1385 A1386 Y1388 G1389 I1392 Y1393 E1451 K1452 G1453 Y1488 P1490 P1859 T1860 G1861 2.7.7.48,2.1.1.56,2.7.7.88,2.1.1.296 P03523 31914397 NHADYNLNSPLISDDIDNLIRKFNSLPIPSMWDSKNWDGVLEMLTSCQANPISTSQMHKWMGSWLMSDNHDASQGYSFLHEVDKEAEITFDVVETFIRGWGNKPIEYIKKERWTDSFKILAYLCQKFLDLHKLTLILNAVSEVELLNLARTFKGKVRRSSHGTNICRIRVPSLGPTFISEGWAYFKKLDILMDRNFLLMVKDVIIGRMQTVLSMVCRIDNLFSEQDIFSLLNIYRIGDKIVERQGNFSYDLIKMVEPICNLKLMKLARESRPLVPQFPHFENHIKTSVDEGAKIDRGIRFLHDQIMSVKTVDLTLVIYGSFRHWGHPFIDYYTGLEKLHSQVTMKKDIDVSYAKALASDLARIVLFQQFNDHKKWFVNGDLLPHDHPFKSHVKENTWPTAAQVQDFGDKWHELPLIKCFEIPDLLDPSIIYSDKSHSMNRSEVLKHVRMNPNTPIPSKKVLQTMLDTKATNWKEFLKEIDEKGLDDDDLIIGLKGKERELKLAGRFFSLMSWKLREYFVITEYLIKTHFVPMFKGLTMADDLTAVIKKMLDSSSGQGLKSYEAICIANHIDYEKWNNHQRKLSNGPVFRVMGQFLGYPSLIERTHEFFEKSLIYYNGRPDLMRVHNNTLINSTSQRVCWQGQEGGLEGLRQKGWTILNLLVIQREAKIRNTAVKVLAQGDNQVICTQYKTKKSRNVVELQGALNQMVSNNEKIMTAIKIGTGKLGLLINDDETMQSADYLNYGKIPIFRGVIRGLETKRWSRVTCVTNDQIPTCANIMSSVSTNALTVAHFAENPINAMIQYNYFGTFARLLLMMHDPALRQSLYEVQDKIPGLHSSTFKYAMLYLDPSIGGVSGMSLSRFLIRAFPDPVTESLSFWRFIHVHARSEHLKEMSAVFGNPEIAKFRITHIDKLVEDPTSLNIAMGMSPANLLKTEVKKCLIESRQTIRNQVIKDATIYLYHEEDRLRSFLWSINPLFPRFLSEFKSGTFLGVADGLISLFQNSRTIRNSFKKKYHRELDDLIVRSEVSSLTHLGKLHLRRGSCKMWTCSATHADTLRYKSWGRTVIGTTVPHPLEMLGPQHRKETPCAPCNTSGFNYVSVHCPDGIHDVFSSRGPLPAYLGSKTSESTSILQPWERESKVPLIKRATRLRDAISWFVEPDSKLAMTILSNIHSLTGEEHGFKRTGSALHRFSTSRMSHGGFASQSTAALTRLMATTDTMRDLGDQNFDFLFQATLLYAQITTTVARDGWITSCTDHYHIACKSCLRPIEEITLDSSMDYTPPDVSHVLKTWRNGEIKQIYPLEGNWKNLAPAEQSYQVGRCIGFLYGDLAYRKSTHAEDSSLFPLSIQGRIRGRGFLKGLLDGLMRASCCQVIHRRSLAHLKRPANAVYGGLIYLIDKLSVSPPFLSLTRSGPIRDELETIPHKIPTSYPTSNRDMGVIVRNYFKYQCRLIEKGKYRSHYSQLWLFSDVLSIDFIGPFSISTTLLQILYKPFLSGKDKNELRELANLSSLLRSGEGWEDIHVKFFTKDILLCPEEIRHACKFGIAKMSYPPWGRESRGTITTIPVYYTTTPYPKMLEMPPRIQNPLLSGIRLGQLPTGAHYKIRSILHGMGIHYRDFLSCGDGSGGMTAALLRENVHSRGIFNSLLELSGSVMRGASPEPPSALETLGGDKSRCVNGETCWEYPSDLCDPRTWDYFLRLKAGLGLQIDLIVMDMEVRDSSTSLKIETNVRNYVHRILDEQGVLIYKTYGTYICESEKNAVTILGPMFKTVDLVQTEFSSSQTSEVYMVCKGLKKLIDEPNPDWSSINESWKNLYAFQSSEQEFARAKKVSTYFTLTGIPSQFIPDPFVNIETMLQIFGVPTGVSHAAALKSSDRPADLLTISLFYMAIISYYNINHIRVGPIPPNPPSDGIAQNVGIAITGISFWLSLMEKDIPLYQQCLAVIQQSFPIRWEAVSVKGGYKQKWSTRGDGLPKDTRISDSLAPIGNWIRSLELVRNQVRLNPFNEILFNQLCRTVDNHLKWSNLRRNTGMIEWINRRISKEDRSILMLKSDLHEENSWRD 6u4b A 2.10 BS01 MG A 1 D386 D388 H540 D378 D380 H532 Q48484 NSVKIYTSHHKPSAFLNAAIIKPLHVGKANSCNEIGCPGDDTGDNISFKNPFYCELTAHYWVWKNEELADYVGFMHYRRHLNFSEKQTFSEDTWGVVNHPCIDEEYEKIFGLNEETIQRCVEGIDILLPKKWSVTAAGSKNNYDHYERGEYLHIRDYQAAIAIVEKLYPEYSTAIKTFNDASDGYYTNMFVMRKDIFVDYSEWLFSILDNLEDAISMNNYNAQEKRVIGHIAERLFNIYIIKLQQDGELKVKELQRTFVSNETFNGALNPVFDSAVPVVISFDDNYAISGGALINSIIRHADKNKNYDIVVLENKVSYLNKTRLVNLTSAHPNVSLRFFDVNAFTEIVHTRAHFSASTYARLFIPQLFRRYDKVVFIDSDTVVKADLGELLDVPLGNNLVAAVKDIVMEGFVKFSAMSASDDGVMPAGEYLQKTLNMNNPDEYFQAGIIVFNVKQMVEENTFAELMRVLKAKKYWFLDQDIMNKVFYSRVTFLPLEWNVYHGNGNTDDFFPNLKFATYMKFLAARKKPKMIHYAGENKPWNTEKVDFYDDFIENIANTPWEMEIYKRQMS 6u4t A 1.36 BS03 PX7 A 2 Q67 L91 Q92 V131 V135 Q64 L88 Q89 V127 V131 4.2.1.1 P00918 31794211 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6uwr A 2.80 BS01 CA A 1 D222 D224 E231 N260 E263 S264 D273 D6 D8 E15 N44 E47 S48 D57 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr A 2.80 BS02 CA A 2 D220 D222 D224 I226 E231 D4 D6 D8 I10 E15 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr A 2.80 BS03 CA A 3 N621 D623 Q644 S646 D734 N735 N405 D407 Q428 S430 D518 N519 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr C 2.80 BS01 CA C 1 D222 D224 E231 N260 Y261 E263 D273 D6 D8 E15 N44 Y45 E47 D57 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr C 2.80 BS02 CA C 2 D220 D222 D224 I226 D228 E231 D4 D6 D8 I10 D12 E15 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr F 2.80 BS01 CA F 1 D222 D224 E231 N260 E263 D273 D6 D8 E15 N44 E47 D57 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr H 2.80 BS01 CA H 1 D222 D224 E231 N260 Y261 E263 S264 D273 D6 D8 E15 N44 Y45 E47 S48 D57 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwr H 2.80 BS03 CA H 3 N621 D623 Q644 G645 S646 D734 N405 D407 Q428 G429 S430 D518 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwt J 3.10 BS02 CA J 2 D220 D222 D224 I226 D228 E231 Y261 D4 D6 D8 I10 D12 E15 Y45 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6uwt N 3.10 BS01 CA N 1 D222 D224 E231 N260 Y261 E263 S264 T266 D273 D6 D8 E15 N44 Y45 E47 S48 T50 D57 O32739 31896582 EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYFNDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPDDRELLVLSVD 6v11 A 1.15 BS01 ADP A 1 H324 Y325 P358 G359 V360 G361 K362 T363 Y493 K509 V541 R542 H65 Y66 P99 G100 V101 G102 K103 T104 Y209 K225 V257 R258 3.4.21.53 A0A3N4AY83 ALKRKIEAAKMPKDAREKTEAELQKLKMATVVRGYIDWMLQVPWNSRSKVKKDLVKAQEVLDTDHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIAKATGRQYVRMALGMPGKLIQKMAKVGVKNPLFLLDEIDKDPASALLEVLDPEQNVAFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKQHLLPKQFERNAIKKGELTIDDSAIMSIIRYYTREAGVRSLEREISKLCRKAVKNLLMDKTVKHIEINGDNLKDFLGVQKVDYGRADTENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGLVLPIGGLKEKLLAAHRGGIKVVLIPDDNKRDLEEIPDNVIADLEIHPVKRIDDVLAIALEHPA 6v11 B 1.15 BS01 ADP B 1 D323 H324 Y325 L327 G359 V360 G361 K362 T363 Y493 H505 K509 V541 R542 D71 H72 Y73 L75 G107 V108 G109 K110 T111 Y214 H226 K230 V262 R263 3.4.21.53 A0A3N4AY83 ALKRKIEAAKMPKDAREKTEAELQKLKMMSPMSAEATVVRGYIDWMLQVPWNSRSKVKKDLVKAQEVLDTDHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIAKATGRQYVRMALGGKLIQKMAKVGVKNPLFLLDEIDKMAPASALLEVLDPEQNVAFNHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKQHLLPKQFERNAIKKGELTIDDSAIMSIIRYYTREAGVRSLEREISKLCRKAVKNLLMDKTVKHIEINGDNLKDFLGVQKVDYGRADTENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGLVLPIGGLKEKLLAAHRGGIKVVLIPDDNKRDLEEIPDNVIADLEIHPVKRIDDVLAIALEHPA 6v11 C 1.15 BS01 ADP C 1 D323 H324 Y325 G359 V360 G361 K362 T363 S364 Y493 I501 H505 K509 V541 R542 D71 H72 Y73 G107 V108 G109 K110 T111 S112 Y222 I230 H234 K238 V269 R270 3.4.21.53 A0A3N4AY83 ALKRKIEAAKMPKDAREKTEAELQKLKMMSPMSAEATVVRGYIDWMLQVPWNSRSKVKKDLVKAQEVLDTDHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIAKATGRQYVRMALGRRTIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMPASALLEVLDPEQNVAFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKQHLLPKQFERNAIKKGELTIDDSAIMSIIYYTREAGVRSLEREISKLCRKAVKNLLMDKTVKHIEINGDNLKDFLGVQKVDYGRADTENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGLVLPIGGLKEKLLAAHRGGIKVVLIPDDNKRDLEEIPDNVIADLEIHPVKRIDDVLAIALEHPA 6v11 E 1.15 BS01 ADP E 1 H324 Y325 L327 G359 V360 G361 K362 T363 S364 Y493 I501 K509 V541 R542 H57 Y58 L60 G92 V93 G94 K95 T96 S97 Y183 I191 K199 V231 R232 3.4.21.53 A0A3N4AY83 ALKRKIEAAKMPKDAREKTEAELQKLKMMSPMSAEATVVRGYIDWMLQAQEVLDTDHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIAKATGRQYVRMALGPGKLIQKMAKVGVKNPLFLLDEIDKASALLEVLDPEQSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKQHLLPKQFERNAIKKGELTIDDSAIMSIIRYYTREAGVRSLEREISKLCRKAVKNLLMDKTVKHIEINGDNLKDFLGVQKVDGRADTENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGLVLPIGGLKEKLLAAHRGGIKVVLIPDDNKRDLEEIPDNVIADLEIHPVKRIDDVLAIALEHPA 6v11 F 1.15 BS01 ADP F 1 D323 H324 Y325 G359 V360 G361 K362 T363 I501 H505 K509 V541 R542 D71 H72 Y73 G107 V108 G109 K110 T111 I225 H229 K233 V265 R266 3.4.21.53 A0A3N4AY83 ALKRKIEAAKMPKDAREKTEAELQKLKMMSPMSAEATVVRGYIDWMLQVPWNSRSKVKKDLVKAQEVLDTDHYGLERVKDRILEYLAVQSRVSKIKGPILCLVGPPGVGKTSLGQSIAKATGRQYVRMALGSMPGKLIQKMAKVGVKNPLFLLDEIDKMPASALLEVLDPEQNVAFNDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKQHLLPKQFERNAIKKGELTIDDSAIMSIIRYYTREAGVRSLEREISKLCRKAVKNLLMDKTVKHIEINGDNLKDFLGVQKVDYGRADTENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINPDFYEKRDIHVHVPEGATPPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGLVLPIGGLKEKLLAAHRGGIKVVLIPDDNKRDLEEIPDNVIADLEIHPVKRIDDVLAIALEHPA 6v63 A 2.02 BS01 III Y 1 M151 N153 I154 N211 R214 Q215 V247 V250 T252 R253 Q254 N255 P258 W273 I283 T285 G286 Y287 L289 Y312 R315 H323 M133 N135 I136 N193 R196 Q197 V229 V232 T234 R235 Q236 N237 P240 W255 I265 T267 G268 Y269 L271 Y294 R297 H305 2.1.1.85 Q86TU7 31911441 VSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYE 6v63 A 2.02 BS02 SAH A 1 R74 E102 E103 F105 P179 T252 R253 D274 M275 C276 N277 H278 Y312 S324 F326 F328 R56 E84 E85 F87 P161 T234 R235 D256 M257 C258 N259 H260 Y294 S306 F308 F310 2.1.1.85 Q86TU7 31911441 VSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYE 6v9z A 3.35 BS01 III C 1 L18 A21 T53 N54 A55 Y56 I59 G71 V72 K73 N90 L97 A98 H99 F100 G135 A342 R498 K499 L11 A14 T46 N47 A48 Y49 I52 G64 V65 K66 N83 L90 A91 H92 F93 G128 A335 R491 K492 A3DCU1 KKYVCVRQYDLTDAGAACLSSIAQYYGLKMSLAKIREMTGTDTQGTNAYGLIHAAKQLGFSAKGVKASKEDLLKDFRLPAIANVIVDNRLAHFVVIYSIKNRIITVADPGKGIVRYSMDDFCSIWTGGLVLLEPGEAFQKGDYTQNMMVKFAGFLKPLKKTVLCIFLASLLYTALGIAGSFYIKFLFDDLIKFEKLNDLHIISAGFAVIFLLQIFLNYYRSILVTKLGMSIDKSIMMEYYSHVLKLPMNFFNSRKVGEIISRFMDASKIRQAISGATLTIMIDTIMAVIGGILLYIQNSSLFFISFIIILLYGIIVTVFNKPIQNANRQIMEDNAKLTSALVESVKGIETIKSFGAEEQTEKSTRDKIETVMKSSFKEGMLYINLSSLTGIVAGLGGIVILWAGAYNVIKGNMSGGQLLAFNALLAYFLTPVKNLIDLQPLIQTAVVASNRLGEILELATEKELREDSDDFVISLKGDIEFRNVDFRYGLRKPVLKNINLTIPKGKTVAIVGESGSGKTTLAKLLMNFYSPEKGDILINGHSIKNISLELIRKKIAFVSQDVFIFSGTVKENLCLGNENVDMDEIIKAAKMANAHDFIEKLPLKYDTFLNESGANLSEGQKQRLAIARALLKKPDILILDEATSNLDSITENHIKDAIYGLEDDVTVIIIAHRLSTIVNCDKIYLLKDGEIVESGSHTELIALKGCYFKMWKQTE 6v9z A 3.35 BS02 III D 1 F615 N617 N622 F608 N610 N615 A3DCU1 KKYVCVRQYDLTDAGAACLSSIAQYYGLKMSLAKIREMTGTDTQGTNAYGLIHAAKQLGFSAKGVKASKEDLLKDFRLPAIANVIVDNRLAHFVVIYSIKNRIITVADPGKGIVRYSMDDFCSIWTGGLVLLEPGEAFQKGDYTQNMMVKFAGFLKPLKKTVLCIFLASLLYTALGIAGSFYIKFLFDDLIKFEKLNDLHIISAGFAVIFLLQIFLNYYRSILVTKLGMSIDKSIMMEYYSHVLKLPMNFFNSRKVGEIISRFMDASKIRQAISGATLTIMIDTIMAVIGGILLYIQNSSLFFISFIIILLYGIIVTVFNKPIQNANRQIMEDNAKLTSALVESVKGIETIKSFGAEEQTEKSTRDKIETVMKSSFKEGMLYINLSSLTGIVAGLGGIVILWAGAYNVIKGNMSGGQLLAFNALLAYFLTPVKNLIDLQPLIQTAVVASNRLGEILELATEKELREDSDDFVISLKGDIEFRNVDFRYGLRKPVLKNINLTIPKGKTVAIVGESGSGKTTLAKLLMNFYSPEKGDILINGHSIKNISLELIRKKIAFVSQDVFIFSGTVKENLCLGNENVDMDEIIKAAKMANAHDFIEKLPLKYDTFLNESGANLSEGQKQRLAIARALLKKPDILILDEATSNLDSITENHIKDAIYGLEDDVTVIIIAHRLSTIVNCDKIYLLKDGEIVESGSHTELIALKGCYFKMWKQTE 6v9z B 3.35 BS01 III D 1 Q51 G52 T53 N54 A55 Y56 I59 G71 V72 K73 N90 A98 F100 G135 R498 K499 Q44 G45 T46 N47 A48 Y49 I52 G64 V65 K66 N83 A91 F93 G128 R491 K492 A3DCU1 KKYVCVRQYDLTDAGAACLSSIAQYYGLKMSLAKIREMTGTDTQGTNAYGLIHAAKQLGFSAKGVKASKEDLLKDFRLPAIANVIVDNRLAHFVVIYSIKNRIITVADPGKGIVRYSMDDFCSIWTGGLVLLEPGEAFQKGDYTQNMMVKFAGFLKPLKKTVLCIFLASLLYTALGIAGSFYIKFLFDDLIKFEKLNDLHIISAGFAVIFLLQIFLNYYRSILVTKLGMSIDKSIMMEYYSHVLKLPMNFFNSRKVGEIISRFMDASKIRQAISGATLTIMIDTIMAVIGGILLYIQNSSLFFISFIIILLYGIIVTVFNKPIQNANRQIMEDNAKLTSALVESVKGIETIKSFGAEEQTEKSTRDKIETVMKSSFKEGMLYINLSSLTGIVAGLGGIVILWAGAYNVIKGNMSGGQLLAFNALLAYFLTPVKNLIDLQPLIQTAVVASNRLGEILELATEKELREDSDDFVISLKGDIEFRNVDFRYGLRKPVLKNINLTIPKGKTVAIVGESGSGKTTLAKLLMNFYSPEKGDILINGHSIKNISLELIRKKIAFVSQDVFIFSGTVKENLCLGNENVDMDEIIKAAKMANAHDFIEKLPLKYDTFLNESGANLSEGQKQRLAIARALLKKPDILILDEATSNLDSITENHIKDAIYGLEDDVTVIIIAHRLSTIVNCDKIYLLKDGEIVESGSHTELIALKGCYFKMWKQTE 6vfs E 3.30 BS01 III G 1 G152 Y153 V154 G90 Y91 V92 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKTRDVSGEGVQQALLKLIEGTVASVPPQGGREFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs E 3.30 BS02 ATP E 1 H77 V78 I79 G80 Q81 T121 G122 S123 G124 K125 T126 L127 L316 I324 A368 R369 H15 V16 I17 G18 Q19 T59 G60 S61 G62 K63 T64 L65 L238 I246 A290 R291 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKTRDVSGEGVQQALLKLIEGTVASVPPQGGREFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs E 3.30 BS03 MG E 1 T126 D184 T64 D122 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKTRDVSGEGVQQALLKLIEGTVASVPPQGGREFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs E 3.30 BS04 ATP D 1 E302 R306 E224 R228 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKTRDVSGEGVQQALLKLIEGTVASVPPQGGREFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs A 3.30 BS01 ADP A 1 H77 V78 I79 Q81 G122 S123 G124 K125 T126 L127 L316 I324 N330 A368 R369 H15 V16 I17 Q19 G52 S53 G54 K55 T56 L57 L199 I207 N213 A251 R252 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHLSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISEGVQQALLKLIEGTVASVPNVDTTNILFICGGAFAGLEKVIRQRTGGIGFGASTKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs F 3.30 BS01 ATP E 1 E302 R306 E192 R196 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKVSGEGVQQALLKLIEGTVASVPPFINVDTTNILFICGGAFAGLEKVIIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs F 3.30 BS02 ADP F 1 H77 V78 I79 G80 Q81 T121 G122 S123 G124 K125 T126 L127 L316 I324 A368 H15 V16 I17 G18 Q19 T59 G60 S61 G62 K63 T64 L65 L206 I214 A258 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKVSGEGVQQALLKLIEGTVASVPPFINVDTTNILFICGGAFAGLEKVIIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs C 3.30 BS01 III G 1 G152 Y153 V154 V202 G90 Y91 V92 V133 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs B 3.30 BS01 III G 1 G152 Y153 V154 G80 Y81 V82 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs B 3.30 BS02 ATP B 1 H77 V78 I79 G80 Q81 G122 S123 G124 K125 T126 L127 L316 I324 A368 R369 H15 V16 I17 G18 Q19 G50 S51 G52 K53 T54 L55 L222 I230 A274 R275 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfs B 3.30 BS03 MG B 1 T126 D184 T54 D112 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfx C 2.90 BS01 III G 1 Y153 V154 Y91 V92 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQGGEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHNADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfx C 2.90 BS03 MG C 1 T126 D184 Q185 T64 D122 Q123 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQGGEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHNADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfx C 2.90 BS04 ATP B 1 E216 E302 R306 E147 E223 R227 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRTRDVSGEGVQQALLKLIEGTVASVPPQGGEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHNADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfx B 2.90 BS02 ATP B 1 H77 V78 I79 Q81 T121 G122 S123 G124 K125 T126 L127 A250 L316 A368 R369 H15 V16 I17 Q19 T59 G60 S61 G62 K63 T64 L65 A180 L241 A293 R294 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfx F 2.90 BS01 ADP F 1 H77 V78 I79 Q81 G122 S123 G124 K125 T126 L127 L316 I324 N330 A368 H15 V16 I17 Q19 G60 S61 G62 K63 T64 L65 L225 I233 N239 A277 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISEGVQQALLKLIEGTVASVPPQGEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHTKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vfx A 2.90 BS01 III G 1 N195 P196 S197 I198 T199 N133 P134 S135 I136 T137 A0A0Y4ZJG4 31916936 KLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGIVYIDQIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHNADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEILDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKAVIEEGREPELVF 6vhf A 2.31 BS01 ZN A 1 C378 C451 C456 H459 C57 C92 C97 H100 G0S1N3 31724694 ALTPEEYAELTASAETRSKLSEQIALCRQMLQLIELAIARREAAIAAGIPGITKDICGYDTRLDTVGAAHQFSLFLQSPQGQSQDPRTAGMCLRKKCKPHNGWGALLTKTVRHDIRELALQIRELLEAEQRVRDGAAGRF