6ech A 2.19 BS01 FBP A 1 L443 T444 K445 T446 S449 W494 R501 G526 R528 P529 G530 S531 G532 Y533 T534 L426 T427 K428 T429 S432 W477 R484 G509 R511 P512 G513 S514 G515 Y516 T517 2.7.1.40 P12928 QELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSHH 6ech A 2.19 BS03 MG A 2 N87 S89 D125 T126 S255 N70 S72 D108 T109 S238 2.7.1.40 P12928 QELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSHH 6ech A 2.19 BS04 MG A 3 R132 D190 G220 D308 R115 D173 G203 D291 2.7.1.40 P12928 QELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSHH 6ech A 2.19 BS05 ATP A 1 T62 P65 R85 N87 H90 Y95 H96 R132 K219 D308 S374 A378 K379 T45 P48 R68 N70 H73 Y78 H79 R115 K202 D291 S357 A361 K362 2.7.1.40 P12928 QELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSHH 6ech A 2.19 BS06 OXL A 1 R85 K282 E284 A305 R306 G307 D308 T340 M372 R68 K265 E267 A288 R289 G290 D291 T323 M355 2.7.1.40 P12928 QELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSHH 6ech B 2.19 BS04 MG B 3 D190 G220 D308 D171 G201 D289 2.7.1.40 P12928 LGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSH 6ech B 2.19 BS06 OXL B 1 K282 E284 A305 R306 G307 D308 T340 M372 K263 E265 A286 R287 G288 D289 T321 M353 2.7.1.40 P12928 LGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSH 6ech C 2.19 BS04 OXL C 1 K282 E284 A305 R306 G307 D308 T340 K261 E263 A284 R285 G286 D287 T319 2.7.1.40 P12928 TAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSHHHHHH 6ech D 2.19 BS04 ATP D 1 T62 P65 R85 N87 H90 Y95 R132 K219 D308 S374 A378 T45 P48 R68 N70 H73 Y78 R115 K202 D291 S357 A361 2.7.1.40 P12928 QELGTAFFQQQQLPAAMADTFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVSH 6h35 A 2.30 BS01 GDP A 1 L22 C23 G24 K25 T26 T27 R53 N141 K142 D144 L145 V169 A170 P171 L21 C22 G23 K24 T25 T26 R52 N140 K141 D143 L144 V168 A169 P170 Q1DB04 31757955 SFINYSSREINCKIVYYGPGLCGKTTNLQYIYNKTAAETKGKLISLSTETDRTLFFDFLPLSLGEIRGFKTRFHLYTVPGQVFYDASRKLILKGVDGVVFVADSQIERMEANMESLENLRINLAEQGYDLNKIPYVIQYNKRDLPNAVTVEEMRKALNHRNIPEYQAVAPTGVGVFDTLKAVAKLVLTELKKG 6hdz A 2.06 BS01 FZK A 1 T233 E235 R264 I278 R279 Q280 F283 K285 E287 E351 I352 S353 S354 N385 S387 A390 R393 T233 E235 R264 I273 R274 Q275 F278 K280 E282 E346 I347 S348 S349 N380 S382 A385 R388 6.1.1.11 A0A3P3Q1W7 MLDPKLVRTQPQEVAARLATRGFQLDVARIEALEEQRKSVQTRTEQLQAERNARSKAIGQAKQRGEDIAPLLADVDRMGSELEEGKRQLDAIQGELDAMLLGIPNLPHESVPVGADEDANVEVRRWGTPKTFDFEVKDHVALGERHGWLDFETAAKLSGARFALMRGPIARLHRALAQFMINLHTAEHGYEEAYTPYLVQAPALQGTGQLPKFEEDLFKIGRDGEADLYLIPTAEVSLTNIVSGQILDAKQLPLKFVAHTPCFRSEADTRGMIRQHQFDKVEMVQIVDPATSYEALEGLTANAERVLQLLELPYRVLALCTGDMGFGSTKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEVLKPYMAGIEVIG 6he3 A 2.16 BS01 FZQ A 1 T233 E235 R264 E266 I278 Q280 F283 K285 E287 E351 I352 S353 S354 N385 S387 A390 R393 T233 E235 R264 E266 I274 Q276 F279 K281 E283 E347 I348 S349 S350 N381 S383 A386 R389 6.1.1.11 A0A3P3Q1W7 MLDPKLVRTQPQEVAARLATRGFQLDVARIEALEEQRKSVQTRTEQLQAERNARSKAIGQAKQRGEDIAPLLADVDRMGSELEEGKRQLDAIQGELDAMLLGIPNLPHESVPVGADEDANVEVRRWGTPKTFDFEVKDHVALGERHGWLDFETAAKLSGARFALMRGPIARLHRALAQFMINLHTAEHGYEEAYTPYLVQAPALQGTGQLPKFEEDLFKIGRDGEADLYLIPTAEVSLTNIVSGQILDAKQLPLKFVAHTPCFRSEARDTRGMIRQHQFDKVEMVQIVDPATSYEALEGLTANAERVLQLLELPYRVLALCTGDMGFGSTKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEVLKPYMAGIEVIG 6hty B 2.22 BS01 GRH B 1 L209 S247 F251 F281 C284 Q285 F288 W299 Y306 M323 H407 I414 F420 L59 S97 F101 F131 C134 Q135 F138 W149 Y156 M173 H257 I264 F270 2.3.1.48 Q15788 31746599 LGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITHSSLTERHKILHRLLQEGSP 6i91 A 1.78 BS01 HEM A 1 N233 L235 F237 K238 D239 G240 T241 R242 I278 M280 F297 R299 H326 V327 A330 H331 P332 L340 R342 L361 F363 F374 V377 Q378 L381 L386 H392 N179 L181 F183 K184 D185 G186 T187 R188 I224 M226 F243 R245 H272 V273 A276 H277 P278 L286 R288 L307 F309 F320 V323 Q324 L327 L332 H338 1.11.1.- Q9RKQ2 GSAVPFHGAHQAGIATPVQDRLHFAAFDVTTEDRAAFVALLKEWTAAARRLTAGHAVGEGAYGGLPEAPPDDTGEALGLKPSRLTLTIGFGPSLFTRFGLADLRPEALADLPKFPGDNLDRARSGGDLCVQACADDPQVAVHAIRNLARIGFGKVVVRWSQLGFGKTSSTTPDKQTPRNLLGFKDGTRNIAGTEKDRLDRFVWAAEKDGTPWMTGGSYLVARRIRMHIETWDRASLQEQEDVFGRDKGEGAPVGKAKERDEPFLKAMKPDAHVRLAHPDSNGGATLLRRGYSFTDGTDGLGRLDAGLFFLAYQRDIRTGFVPVQRNLATDALNEYIQHVGSAVFAVPPGVRDADDWWGSTLF 6i9o A 1.55 BS01 MLD A 1 F31 D32 A65 D66 K68 G69 P70 A72 Y73 N74 L77 R81 R150 F27 D28 A61 D62 K64 G65 P66 A68 Y69 N70 L73 R77 R146 A0A0E2LQD9 HHHHSSGVDLGTENLYFQSLQNIFYDFDKATLRPESMKSLDELIRILTDNPDIRIELGSHADRKGPDAYNLGLSDRRAKSVVDYLTSRGIAADRLTWKGYGKSVPKTVTAKIAERHDFLKEGDVLTEEFVAPLTEEQQSVCDQLNRRTEFRVIE 6i9o D 1.55 BS01 MLD D 1 F31 D32 A65 D66 K68 P70 Y73 N74 L77 R81 R150 F23 D24 A57 D58 K60 P62 Y65 N66 L69 R73 R142 A0A0E2LQD9 SSGVDLGTENLYFQSLQNIFYDFDKATLRPESMKSLDELIRILTDNPDIRIELGSHADRKGPDAYNLGLSDRRAKSVVDYLTSRGIAADRLTWKGYGKSVPKTVTAKIAERHDFLKEGDVLTEEFVAPLTEEQQSVCDQLNRRTEFRVIE 6iql A 3.50 BS01 L74 A 1 F88 S91 G96 W98 M109 D112 V113 F330 F331 Y358 F58 S61 G66 W68 M79 D82 V83 F293 F294 Y321 P51436 31750832 GAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIWNLCAISVDRFVAVTGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPENRDYVVYSSVCSFFLPCILMLLLYWATFRGLRRWEADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLKITGRERKAMRVLAVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSV 6iql B 3.50 BS01 L74 B 1 F88 S91 G96 W98 M109 D112 V113 C180 R181 F330 F331 Y358 F58 S61 G66 W68 M79 D82 V83 C133 R134 F291 F292 Y319 P51436 31750832 GAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIWNLCAISVDRFVAVTVGQCQLLLIAATWLLSAAVASPVVCGVCRLENRDYVVYSSVCSFFLPCILMLLLYWATFRGLRRWEADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLKITGRERKAMRVLAVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVF 6iur F 3.33 BS01 TME F 1 L55 D57 I59 Y60 S95 L49 D51 I53 Y54 S89 P30153 FDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSL 6iux A 1.20 BS02 AR6 A 1 E25 D55 D56 A98 G100 G101 A102 S103 S124 H125 G127 G128 C129 G130 M133 H163 H165 T167 Y263 S264 S269 S270 D302 D304 S305 E26 D56 D57 A99 G101 G102 A103 S104 S125 H126 G128 G129 C130 G131 M134 H164 H166 T168 Y264 S265 S270 S271 D303 D305 S306 3.2.2.19 P54922 GSEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLDALDVGRWRVSDDTVMHLATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPNGWRIPFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASALFTAYAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGILDGESAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRAFFHGGDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKEDTVISL 6iuy A 2.20 BS01 NAD A 1 S339 G340 A341 W342 A343 H374 Y396 A426 P427 H428 F430 T454 K455 N486 I487 A488 N540 R603 G634 Q635 K636 Q638 S233 G234 A235 W236 A237 H268 Y290 A320 P321 H322 F324 T348 K349 N380 I381 A382 N434 R497 G528 Q529 K530 Q532 1.1.1.8 Q52ZA0 31762135 SEPSEQVLDLWQQADAVCFDVDRTVTTDASVGLLAKFMGIEDEAQSLTEQANRGEINLTKAFEDRLAKLNFTPTDIDRFLEEHPAHTRLVPGVENLIAALKARGVEVFLISGGFREMALPIASHLKIPAKNVFCNTMSWQLDDHGEPVRLSHFKSRAIERIRRKYPYNNIIMVGDGFSDLEAMQGSPDGADAFICFGGVMQRPAVASQADWFVRSYDELMAKLKRYKVTMVGSGAWACTAVRMVAQSTAEAAQLPGSVFEKEVTMWVHEEKHSGRNLIEYINENHENPIYLPGIDLGENVKATSDLIEAVRGADALIFCAPHQFMHGICKQLAAARVVGRGVKAISLTKGMRVRAEGPQLISQMVSRILGIDCSVLMGANIAGDIAKEELSEAVIAYANRESGSLWQQLFQRPYFAINLLADVPGAEMCGTLKNIVAVGAGIGDGLGVGPNSKASILRQGLSEMRKFCKFISPSVRDDTFFESCGVADLIASSYGGRNRRVAEAWAQKRIAGDDQVTFEKLEKEMLNGQKLQGVLTSDEVQEILHARGWELEFPLFTTINRIIHGEVPPTMILRYRVACSMPSMP 6iuy A 2.20 BS02 13P A 1 K455 K539 N540 G602 R603 N604 K349 K433 N434 G496 R497 N498 1.1.1.8 Q52ZA0 31762135 SEPSEQVLDLWQQADAVCFDVDRTVTTDASVGLLAKFMGIEDEAQSLTEQANRGEINLTKAFEDRLAKLNFTPTDIDRFLEEHPAHTRLVPGVENLIAALKARGVEVFLISGGFREMALPIASHLKIPAKNVFCNTMSWQLDDHGEPVRLSHFKSRAIERIRRKYPYNNIIMVGDGFSDLEAMQGSPDGADAFICFGGVMQRPAVASQADWFVRSYDELMAKLKRYKVTMVGSGAWACTAVRMVAQSTAEAAQLPGSVFEKEVTMWVHEEKHSGRNLIEYINENHENPIYLPGIDLGENVKATSDLIEAVRGADALIFCAPHQFMHGICKQLAAARVVGRGVKAISLTKGMRVRAEGPQLISQMVSRILGIDCSVLMGANIAGDIAKEELSEAVIAYANRESGSLWQQLFQRPYFAINLLADVPGAEMCGTLKNIVAVGAGIGDGLGVGPNSKASILRQGLSEMRKFCKFISPSVRDDTFFESCGVADLIASSYGGRNRRVAEAWAQKRIAGDDQVTFEKLEKEMLNGQKLQGVLTSDEVQEILHARGWELEFPLFTTINRIIHGEVPPTMILRYRVACSMPSMP 6iuy A 2.20 BS03 MG A 1 D116 D118 D281 D20 D22 D175 1.1.1.8 Q52ZA0 31762135 SEPSEQVLDLWQQADAVCFDVDRTVTTDASVGLLAKFMGIEDEAQSLTEQANRGEINLTKAFEDRLAKLNFTPTDIDRFLEEHPAHTRLVPGVENLIAALKARGVEVFLISGGFREMALPIASHLKIPAKNVFCNTMSWQLDDHGEPVRLSHFKSRAIERIRRKYPYNNIIMVGDGFSDLEAMQGSPDGADAFICFGGVMQRPAVASQADWFVRSYDELMAKLKRYKVTMVGSGAWACTAVRMVAQSTAEAAQLPGSVFEKEVTMWVHEEKHSGRNLIEYINENHENPIYLPGIDLGENVKATSDLIEAVRGADALIFCAPHQFMHGICKQLAAARVVGRGVKAISLTKGMRVRAEGPQLISQMVSRILGIDCSVLMGANIAGDIAKEELSEAVIAYANRESGSLWQQLFQRPYFAINLLADVPGAEMCGTLKNIVAVGAGIGDGLGVGPNSKASILRQGLSEMRKFCKFISPSVRDDTFFESCGVADLIASSYGGRNRRVAEAWAQKRIAGDDQVTFEKLEKEMLNGQKLQGVLTSDEVQEILHARGWELEFPLFTTINRIIHGEVPPTMILRYRVACSMPSMP 6iuy B 2.20 BS01 NAD B 1 S339 G340 A341 W342 A343 H374 E376 Y396 P427 F430 L453 T454 K455 N486 I487 A488 N540 R603 G634 Q635 K636 Q638 S180 G181 A182 W183 A184 H215 E217 Y237 P268 F271 L294 T295 K296 N327 I328 A329 N381 R444 G475 Q476 K477 Q479 1.1.1.8 Q52ZA0 31762135 LYFQSEPSEQVLDLWQQADAVCFDVDRTVTTDASVGRFLEEHPAHTRLVPGVENLIAALKARGVEVFLISGGFREMALPIASHLKIPAKNVFCNTMSSHFKSRAIERIRRKYPYNNIIMVGDGFSDLEAMQGSPDGADAFICFGGVMQRPAVASQADWFVRSYDELMAKLKRYKVTMVGSGAWACTAVRMVAQSTAEAAQLPGSVFEKEVTMWVHEEKHSGRNLIEYINENHENPIYLPGIDLGENVKATSDLIEAVRGADALIFCAPHQFMHGICKQLAAARVVGRGVKAISLTKGMRVRAEGPQLISQMVSRILGIDCSVLMGANIAGDIAKEELSEAVIAYANRESGSLWQQLFQRPYFAINLLADVPGAEMCGTLKNIVAVGAGIGDGLGVGPNSKASILRQGLSEMRKFCKFISPSVRDDTFFESCGVADLIASSYGGRNRRVAEAWAQKRIAGDDQVTFEKLEKEMLNGQKLQGVLTSDEVQEILHARGWELEFPLFTTINRIIHGEVPPTMILRYRVACSMPSM 6iuy B 2.20 BS02 13P B 1 K455 I487 K539 N540 G602 R603 N604 K296 I328 K380 N381 G443 R444 N445 1.1.1.8 Q52ZA0 31762135 LYFQSEPSEQVLDLWQQADAVCFDVDRTVTTDASVGRFLEEHPAHTRLVPGVENLIAALKARGVEVFLISGGFREMALPIASHLKIPAKNVFCNTMSSHFKSRAIERIRRKYPYNNIIMVGDGFSDLEAMQGSPDGADAFICFGGVMQRPAVASQADWFVRSYDELMAKLKRYKVTMVGSGAWACTAVRMVAQSTAEAAQLPGSVFEKEVTMWVHEEKHSGRNLIEYINENHENPIYLPGIDLGENVKATSDLIEAVRGADALIFCAPHQFMHGICKQLAAARVVGRGVKAISLTKGMRVRAEGPQLISQMVSRILGIDCSVLMGANIAGDIAKEELSEAVIAYANRESGSLWQQLFQRPYFAINLLADVPGAEMCGTLKNIVAVGAGIGDGLGVGPNSKASILRQGLSEMRKFCKFISPSVRDDTFFESCGVADLIASSYGGRNRRVAEAWAQKRIAGDDQVTFEKLEKEMLNGQKLQGVLTSDEVQEILHARGWELEFPLFTTINRIIHGEVPPTMILRYRVACSMPSM 6ivy A 2.00 BS01 FE A 1 H39 E87 R129 Y223 Y224 H11 E59 R101 Y195 Y196 Q9HVA8 PVTLTLYNGQHAATGIAIAKAFQDKTGIQVKIRKGGDGQLASQITEEGARSPADVLYTEESPPLIRLASAGLLAKLEPETLALVEPEHAGGNGDWIGITARTRVLAYNPKKIDEKDLPKSLMDLSDPSWSGRFGFVPTSGAFLEQVAAVIKLKGQEEAEDWLTGLKAFGSIYTNNVTAMKAVENGEVDMALINNYYWYTLKKEKGELNSRLHYFGNQDPGALVTVSGAAVLKSSKHPREAQQFVAFMLSEEGQKAILSQSAEYPMRKGMQADPALKPFAELDPPKLTPADLGEASEALSLERDVGL 6ivy B 2.00 BS01 FE B 1 H39 E87 Y223 Y224 H11 E59 Y195 Y196 Q9HVA8 PVTLTLYNGQHAATGIAIAKAFQDKTGIQVKIRKGGDGQLASQITEEGARSPADVLYTEESPPLIRLASAGLLAKLEPETLALVEPEHAGGNGDWIGITARTRVLAYNPKKIDEKDLPKSLMDLSDPSWSGRFGFVPTSGAFLEQVAAVIKLKGQEEAEDWLTGLKAFGSIYTNNVTAMKAVENGEVDMALINNYYWYTLKKEKGELNSRLHYFGNQDPGALVTVSGAAVLKSSKHPREAQQFVAFMLSEEGQKAILSQSAEYPMRKGMQADPALKPFAELDPPKLTPADLGEASEALSLERDVGLN 6j17 A 1.98 BS01 ATP A 1 T1064 A1109 R1110 S1111 G1112 K1113 T1114 T1115 R1141 R1245 A1292 G1293 L1309 I1310 N1311 T5 A50 R51 S52 G53 K54 T55 T56 R82 R186 A233 G234 L250 I251 N252 P9WNA9 31758528 RLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRWTFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPL 6j18 A 2.00 BS01 ATP A 1 R1180 E1181 C1182 G1183 R1184 T1185 T1186 R1368 G1369 V1384 L1392 H1394 R56 E57 C58 G59 R60 T61 T62 R244 G245 V260 L268 H270 P9WNA5 31758528 RLPARFGVEQVRELASRDTRQGVGAGGIAWAISELDLAPVYLNFAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGASSAPPPAPGRPSAQVWLVDPRRQLLTALGSDYVERFAYNLDGVVAMMGELAAALAGREPPPGLSAEELLSRSWWSGPEIFLIVDDIQQLPPGFDSPLHKAVPFVNRAADVGLHVIVTRTFGGWSSAGSDPMLRALHQANAPLLVMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVFVQVAATEVRRLEHHH 6j19 A 1.98 BS01 III B 1 L423 A425 E437 A441 L442 N445 L446 R449 F469 V471 L104 A106 E118 A122 L123 N126 L127 R130 F150 V152 P9WNB1 31758528 PVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQAFLVSPDGKEVIQAPYIEPP 6j19 A 1.98 BS02 ATP A 1 E326 R327 A378 K379 S380 G381 K382 T383 T384 R410 P558 G559 Q573 A574 P575 Y576 E7 R8 A59 K60 S61 G62 K63 T64 T65 R91 P239 G240 Q254 A255 P256 Y257 P9WNB1 31758528 PVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQAFLVSPDGKEVIQAPYIEPP 6j2m A 1.13 BS01 FK5 A 1 Y396 F407 D408 F416 S424 V425 I426 W429 G451 Y452 I461 F469 Y30 F41 D42 F50 S58 V59 I60 W63 G85 Y86 I95 F103 5.2.1.8 Q93ZG9 YPNGLIVEELSMGKPNGKRADPGKTVSVRYIGKLQKNGKIFDSNIGKSPFKFRLGIGSVIKGWDVGVNGMRVGDKRKLTIPPSMGYGVKGAGGQIPPNSWLTFDVELINVQ 6j8y C 2.40 BS01 III D 1 N47 G48 I49 K50 F64 I65 Q66 K155 I157 A212 K240 V241 S242 R244 Q254 M256 F266 N33 G34 I35 K36 F50 I51 Q52 K136 I138 A193 K221 V222 S223 R225 Q235 M237 F247 3.1.11.2 O60671 YSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAGIFQEFKVQEESVTFRINLTVLLDCLSIFGSSPTLTALRMCYQGYGYPLMLFLEEGGVVTVCKINTQEPTLDFDFCSTNVINKIILQSEGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSSHLDYPKDSDLMEAFHCNQTQVNRYKISLLKPSTKALVLSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPD 6jbr A 2.03 BS01 T6P A 1 R22 G42 G43 L44 Y99 W108 D153 Y154 H155 H181 I251 R327 D388 G389 M390 N391 L392 R8 G28 G29 L30 Y85 W94 D139 Y140 H141 H167 I237 R313 D374 G375 M376 N377 L378 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr A 2.03 BS02 UDP A 1 S41 G42 G43 T46 V287 R289 K294 V324 S365 V366 L371 M390 L392 V393 E396 S27 G28 G29 T32 V273 R275 K280 V310 S351 V352 L357 M376 L378 V379 E382 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr B 2.03 BS01 T6P B 1 R22 G42 G43 L44 Y99 D153 H155 H181 H212 I251 R327 D388 G389 M390 N391 R8 G28 G29 L30 Y85 D139 H141 H167 H198 I237 R313 D374 G375 M376 N377 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr D 2.03 BS01 T6P D 1 R22 S41 G42 G43 L44 Y99 W108 D153 Y154 H155 H181 H212 R289 R327 D388 G389 M390 N391 R8 S27 G28 G29 L30 Y85 W94 D139 Y140 H141 H167 H198 R275 R313 D374 G375 M376 N377 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr F 2.03 BS01 T6P F 1 R22 S41 G43 L44 Y99 D153 H155 H181 I251 R327 M390 R8 S27 G29 L30 Y85 D139 H141 H167 I237 R313 M376 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr H 2.03 BS01 T6P H 1 R22 S41 G42 G43 L44 Y99 D153 Y154 H155 H181 H212 R327 M390 L392 R8 S27 G28 G29 L30 Y85 D139 Y140 H141 H167 H198 R313 M376 L378 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr K 2.03 BS01 T6P K 1 R22 S41 G42 L44 Y99 W108 D153 Y154 H155 H181 T182 R327 D388 M390 N391 R8 S27 G28 L30 Y85 W94 D139 Y140 H141 H167 T168 R313 D374 M376 N377 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr M 2.03 BS01 T6P M 1 R22 G43 L44 Y99 W108 D153 Y154 H155 H181 I251 R289 R327 D388 G389 M390 L392 R8 G29 L30 Y85 W94 D139 Y140 H141 H167 I237 R275 R313 D374 G375 M376 L378 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbr O 2.03 BS01 T6P O 1 R22 G42 L44 Y99 W108 D153 Y154 H155 H181 T182 R327 D388 G389 M390 N391 L392 R8 G28 L30 Y85 W94 D139 Y140 H141 H167 T168 R313 D374 G375 M376 N377 L378 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSDDGQYSFSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jbw A 2.65 BS01 UDP A 1 V287 R289 K294 V324 S365 V366 L371 M390 L392 V393 E396 V265 R267 K272 V302 S343 V344 L349 M368 L370 V371 E374 2.4.1.15 G4NHF4 31455720 RLLLISNRLPITIKRSMSSGGLVTGLSGLAKTTSFQWYGWPGLEVPDAEAGPVVQRLKNEYGAHPVFVDDELADRHYNGFANSILWPLFHYHPGEITFDESAWSAYKEVNRLFAQTVVKDVQDGDMIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVRQALLQGVLHCDLLGFHTYDYARHFLSSCSRILSAPTTPNGVQFAGRFVTVGAFPIGIDPEKFVEGLQKPKVQQRIAALTRKFEGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELAALYAVSDVCLVSSTRDGMNLVSYEYIATQRDRHGVMILSEFTGAAQSLSGSLIVNPWNTEELANAIHDAVTMGPEQREANFKKLERYVFKYTSAWWGSSFVAELNRL 6jd5 A 2.20 BS01 ATP A 1 Q1186 G1187 C1188 G1189 K1190 T1191 T1192 P1370 G1371 V1387 Y1389 Q55 G56 C57 G58 K59 T60 T61 P239 G240 V256 Y258 O05450 31758528 SLQRLPQRVELSAIVEHEAVGDDLSIAFAIGERHELGPVPIKLRESPGLMILGRQGCGKTTALVAIGEAVMNRFSPQQAQLTLIDPKTAPHGLRDLHAPGYVRAYAYDQDEIDEVITELAQQILLPRLPPKGLSQEELRALKPWEGPRHFVLIDDVQDLRPAQSYPQKPPVGAALWKLMERARQVGLHVFSTRNSANWATMPMDPWVKSQTSAKVAQLYMDNDPQNRINRSVRAQTLPPGRGLLVGADGDVEGILVGYPS 6jz0 A 2.86 BS01 CKO A 1 L718 V726 A743 K745 M766 T790 Q791 M793 P794 C797 D800 R841 L844 D855 L23 V31 A48 K50 M70 T94 Q95 M97 P98 C101 D104 R145 L148 D159 2.7.10.1 P00533 31560541 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELRATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLMDEEDMDDVVDADEYLIP 6kot A 2.15 BS01 DQ0 A 1 I14 C15 A16 L46 D54 M55 F58 R59 N108 I112 F116 R122 L164 Y170 T185 I12 C13 A14 L40 D48 M49 F52 R53 N90 I94 F98 R104 L146 Y152 T167 D9N170 31685330 EQVCDVFDIYAICACCKVESKKNEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKEKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTEDDFVYFNFNKEKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDM 6kot A 2.15 BS02 NDP A 1 C15 A16 L40 G41 G44 V45 L46 G105 R106 T107 N108 L127 S128 R129 T130 N144 K145 L164 G165 G166 S167 V168 V169 Y170 E172 V195 C13 A14 L34 G35 G38 V39 L40 G87 R88 T89 N90 L109 S110 R111 T112 N126 K127 L146 G147 G148 S149 V150 V151 Y152 E154 V177 D9N170 31685330 EQVCDVFDIYAICACCKVESKKNEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKEKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTEDDFVYFNFNKEKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDM 6kp2 A 1.97 BS02 DQ3 A 1 I14 C15 A16 D54 M55 F58 N108 I112 L119 L164 Y170 T185 I11 C12 A13 D44 M45 F48 N86 I90 L97 L142 Y148 T163 D9N170 31685330 QVCDVFDIYAICACCKVENEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKKKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTEEDDFVYFNFNKKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMA 6kp2 B 1.97 BS01 NDP B 1 C15 A16 L40 G41 G44 V45 L46 G105 R106 T107 N108 L127 S128 R129 T130 N144 L164 G166 S167 V168 V169 Y170 E172 C12 A13 L29 G30 G33 V34 L35 G86 R87 T88 N89 L108 S109 R110 T111 N125 L145 G147 S148 V149 V150 Y151 E153 D9N170 31685330 QVCDVFDIYAICACCKVEEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKETVDNKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTDDEEEDDFVYFNFNKENKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDMAA 6kp7 B 1.97 BS04 DQ9 B 1 I14 C15 L46 D54 M55 F58 R59 N108 I112 F116 L164 Y170 T185 I9 C10 L41 D49 M50 F53 R54 N93 I97 F101 L149 Y155 T170 D9N170 31685330 CDVFDIYAICACCKVESKNEGKKNEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKNSKKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTDDEEEDDFVYFNFNKENKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMD 6kpr A 2.10 BS03 DQF A 1 I14 C15 A16 V45 L46 D54 F58 N108 S111 I112 L164 Y170 T185 I12 C13 A14 V39 L40 D48 F52 N91 S94 I95 L147 Y153 T168 D9N170 31685330 EQVCDVFDIYAICACCKVESKKNEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKEKKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTNNDDEEEDDFVYFNFNKENKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDM 6kpr B 2.10 BS04 DQF B 1 I14 C15 V45 L46 D54 M55 F58 N108 I112 P113 L164 Y170 T185 I12 C13 V36 L37 D45 M46 F49 N92 I96 P97 L148 Y154 T169 D9N170 31685330 EQVCDVFDIYAICACCKVESEVFNNYTFRGLGNKGVLPWKCISLDMKYFRAVTTYVNESKYEKLKYKRCKYLNKETVDSKKLQNVVVMGRTNWESIPKKFKPLSNRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFILGGSVVYQEFLEKKLIKKIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTNNDDEEEDDFVYFNFNKENKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMD 6ktb A 2.50 BS01 MG A 1 E11 H77 E99 E102 E11 H77 E99 E102 Q9K943 31738781 MPTPSMEDYLERIYLLIEEKGYARVSDIAEALEVHPSSVTKMVQKLDKSDYLVYERYRGLILTAKGKKIGKRLVYRHDLLEDFLKMIGVDSDHIYEDVEGIEHHLSWDAIDRIGDLVQYFQEDPSRLNDLREVQKKNE 6ktb B 2.50 BS02 MN B 2 D8 E99 E102 H103 D8 E99 E102 H103 Q9K943 31738781 MPTPSMEDYLERIYLLIEEKGYARVSDIAEALEVHPSSVTKMVQKLDKSDYLVYERYRGLILTAKGKKIGKRLVYRHDLLEDFLKMIGVDSDHIYEDVEGIEHHLSWDAIDRIGDLVQYFQEDPSRLNDLREVQKKNE 6kuw A 2.80 BS01 E33 A 1 Y127 L128 D131 V132 C135 L204 S214 S218 W395 F398 F399 Y402 F419 F423 Y427 Y87 L88 D91 V92 C95 L158 S168 S172 W415 F418 F419 Y422 F439 F443 Y447 PPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQWWCGVYLALDVLFCTSSAVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSVAQAREKRFTFVLAVVMGVWVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFR 6kuw A 2.80 BS02 CLR A 1 Y46 L54 V58 L61 F64 F421 W424 S431 Y6 L14 V18 L21 F24 F441 W444 S451 PPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQWWCGVYLALDVLFCTSSAVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSVAQAREKRFTFVLAVVMGVWVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFR 6kuw B 2.80 BS02 CLR B 1 Y46 V58 F60 L61 F421 W424 C428 Y6 V18 F20 L21 F440 W443 C447 PPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQWWCGVYLALDVLFCTSSAVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSVAQAREKRFTFVLAVVMGVWVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILF 6kux A 2.70 BS01 E3F A 1 Y109 D113 V114 E189 I190 F390 F391 F408 F412 Y416 Y81 D85 V86 E152 I153 F322 F323 F340 F344 Y348 SLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSAWHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCR 6kuy A 3.20 BS01 E39 A 1 D113 V114 C117 S204 W387 F390 F391 F412 Y416 D81 V82 C85 S162 W314 F317 F318 F339 Y343 TLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSAWHLCAISLDRYWSITQAIEYNLKRTPRRIKAIILTVWVISAVISFPPLISIPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCR 6kyh F 3.30 BS01 GNP F 1 G13 V14 G15 K16 S17 A18 F28 V29 D30 E31 Y32 P34 T35 A59 G60 N116 K117 D119 L120 A146 G13 V14 G15 K16 S17 A18 F28 V29 D30 E31 Y32 P34 T35 A59 G60 N116 K117 D119 L120 A146 Q61411 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHK 6kyh G 3.30 BS01 GNP G 1 G12 G13 V14 G15 K16 S17 A18 D30 Y32 P34 T35 A59 G60 Q61 N116 K117 D119 S145 A146 G12 G13 V14 G15 K16 S17 A18 D30 Y32 P34 T35 A59 G60 Q61 N116 K117 D119 S145 A146 Q61411 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6kyh H 3.30 BS01 GNP H 1 G12 G13 V14 G15 K16 S17 A18 V29 D30 E31 Y32 P34 T35 A59 G60 Q61 N116 K117 D119 L120 S145 A146 G12 G13 V14 G15 K16 S17 A18 V29 D30 E31 Y32 P34 T35 A59 G60 Q61 N116 K117 D119 L120 S145 A146 Q61411 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6kyh H 3.30 BS02 MG H 1 K16 S17 T35 D57 K16 S17 T35 D57 Q61411 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6kyh E 3.30 BS01 GNP E 1 G13 G15 K16 S17 A18 F28 V29 D30 E31 Y32 P34 T35 G60 Q61 N116 K117 D119 L120 A146 G13 G15 K16 S17 A18 F28 V29 D30 E31 Y32 P34 T35 G60 Q61 N116 K117 D119 L120 A146 Q61411 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6kyk C 2.82 BS01 GNP C 1 G12 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 A59 G60 N116 K117 D119 S147 A148 K149 G14 G15 V16 G17 K18 S19 A20 F30 V31 E32 Y34 P36 T37 A61 G62 N118 K119 D121 S149 A150 K151 P61224 PHMREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 6kyk D 2.82 BS01 GNP D 1 G12 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 A59 G60 N116 K117 D119 L120 S147 A148 G13 G14 V15 G16 K17 S18 A19 F29 V30 E31 Y33 P35 T36 A60 G61 N117 K118 D120 L121 S148 A149 P61224 HMREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 6kyk F 2.82 BS01 GNP F 1 G13 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 A59 G60 N116 K117 D119 L120 S147 A148 K149 G14 G16 K17 S18 A19 F29 V30 E31 Y33 P35 T36 A60 G61 N117 K118 D120 L121 S148 A149 K150 P61224 HMREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 6l18 A 1.90 BS01 TMP A 1 K28 Y96 C148 R168 S169 N170 D171 N179 H216 Y218 K28 Y96 C148 R168 S169 N170 D171 N179 H216 Y218 2.1.2.8 P08773 31705139 MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFGALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGFRNNYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRHFYLVDHWWKTGETHISKKDYVGKYA 6l4c A 3.19 BS01 CU A 1 Y5 C276 P277 H278 H305 Y3 C258 P259 H260 H287 Q8S4P9 31753489 NPYVFQDEHFESRVKTEEGRVQVLENFTKRSRLLSGIENFRLAILEANPHTFISPAHFDAELVLFVAKGRATITMVREEKRESFNVEHGDIIRIPAGTPVYMINRDENEKLFIVKILQPVSAPGHFEAFYGAGGEDPESFYRAFSWEVLEAALKVRREQLEKVFGEQSKGSIVKASREKIRALSSGPINLLHKHPSQSNQFGRLYEAHPDDHKQLQDLDLMVSFANITKGSMAGPYYNSRATKISVVVEGEGFFEMACPHLSSSSGSYQKISARLRRGVVFVAPAGHPVAVIASQNNNLQVLCFEVNAHGNSRFPLAGKGNIVNEFERDAKELAFNLPSREVERIFKNQDQAFFFPGPN 6l4c B 3.19 BS01 CU B 1 Y5 C276 H278 H305 Y3 C274 H276 H303 Q8S4P9 31753489 NPYVFQDEHFESRVKTEEGRVQVLENFTKRSRLLSGIENFRLAILEANPHTFISPAHFDAELVLFVAKGRATITMVREEKRESFNVEHGDIIRIPAGTPVYMINRDENEKLFIVKILQPVSAPGHFEAFYGAGGEDPESFYRAFSWEVLEAALKVRREQLEKVFGEQSKGSIVKASREKIRALSQHEEGPPRIWPFGGESSGPINLLHKHPSQSNQFGRLYEAHPDDHKQLQDLDLMVSFANITKGSMAGPYYNSRATKISVVVEGEGFFEMACPHLSSSSGSYQKISARLRRGVVFVAPAGHPVAVIASQNNNLQVLCFEVNAHGNSRFPLAGKGNIVNEFERDAKELAFNLPSREVERIFKNQDQAFFFPG 6l4c C 3.19 BS01 CU C 1 C276 P277 H278 H305 C258 P259 H260 H283 Q8S4P9 31753489 NPYVFQDEHFESRVKTEEGRVQVLENFTKRSRLLSGIENFRLAILEANPHTFISPAHFDAELVLFVAKGRATITMVREEKRESFNVEHGDIIRIPAGTPVYMINRDENEKLFIVKILQPVSAPGHFEAFYGAGGEDPESFYRAFSWEVLEAALKVRREQLEKVFGEQSKGSIVKASREKIRALSSGPINLLHKHPSQSNQFGRLYEAHPDDHKQLQDLDLMVSFANITKGSMAGPYYNSRATKISVVVEGEGFFEMACPHLSSSQKISARLRRGVVFVAPAGHPVAVIASQNNNLQVLCFEVNAHGNSRFPLAGKGNIVNEFERDAKELAFNLPSREVERIFKNQDQAFFFPG 6l4m A 3.30 BS01 SAL A 1 F228 G247 M249 Y260 N262 K267 V269 I331 F339 I349 G351 K361 F211 G230 M232 Y243 N245 K250 V252 I281 F289 I299 G301 K311 B0JEU3 31753489 NPYLFESQRFRSRFRASHGDFRILERFNQRSQLLKGIEKYRVAILELEPQSFVLPHHCDGEAIYVVVKGQGVINIAEQDNKNSFNLQKGDVIRLFAGSNVYLLNKDNNEKLFVYVLAKSVNAPGNLQEYFSAGGQNPESFYRAFSSDILESAFNNPRDKLERLFGQHKEGIIIKASEEQIRAISEHASRSTQGPFNLMKERPVFESRFGQFFEARPERYEQLRDLDAAVGFMNINQGGMVLPYYNTKSTKLVMVIEGNARFEMACYQKIRGNLNVGDVLVIPAGHPITFVATGNSNLRIVGFGVDAENNKKNFLAGKQNIWRNIDREAKELSFSMPGREVEEIFQRQDQSYFVAGPE 6lco A 2.00 BS03 IOD A 1 S235 P236 F239 T425 S235 P236 F239 T425 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 6lco A 2.00 BS04 IOD A 2 A44 R45 W46 N341 V342 W452 A44 R45 W46 N341 V342 W452 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 6lco A 2.00 BS06 IOD A 4 E363 I559 T560 K561 E363 I559 T560 K561 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 6lco A 2.00 BS10 IOD A 8 F254 R255 F381 F254 R255 F381 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 6lco A 2.00 BS14 OSM A 2 S359 L361 P367 E373 K402 S359 L361 P367 E373 K402 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 6lco A 2.00 BS15 OSM A 3 T357 E373 L374 P375 T357 E373 L374 P375 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 6n7e A 3.50 BS01 ANP A 1 T451 F457 Y478 T479 R480 I481 P482 L545 T568 E570 D571 D586 T21 F27 Y48 T49 R50 I51 P52 L115 T127 E129 D130 D145 Q9H8M5 ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASQVYIPDYSVRALSDLQFVKISRQQYQNALMLEHHHH 6n7e A 3.50 BS02 MG A 1 D504 D506 D74 D76 Q9H8M5 ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASQVYIPDYSVRALSDLQFVKISRQQYQNALMLEHHHH 6n7e B 3.50 BS01 ANP B 1 T451 D455 C456 F457 Y478 T479 R480 I481 P482 L545 T568 E570 D571 I581 E584 Y588 T22 D26 C27 F28 Y49 T50 R51 I52 P53 L116 T129 E131 D132 I142 E145 Y149 Q9H8M5 EELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQFYEVLGIVTLEDVIEEIIKSEILDETDLYFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTAVYIPDYSVRALSDLQFVKISRQQYQNALMLEHHHHH 6n7e B 3.50 BS02 MG B 1 E570 E584 E131 E145 Q9H8M5 EELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQFYEVLGIVTLEDVIEEIIKSEILDETDLYFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTAVYIPDYSVRALSDLQFVKISRQQYQNALMLEHHHHH 6n7e C 3.50 BS01 MG B 2 D504 D506 D74 D76 Q9H8M5 ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIIVTLEDVIEEIIKSEILDETDLYAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVIDNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMLEHHHH 6n7e C 3.50 BS02 ANP C 1 T451 D455 F457 Y478 T479 R480 I481 P482 L545 T568 E570 D571 D586 T21 D25 F27 Y48 T49 R50 I51 P52 L115 T120 E122 D123 D138 Q9H8M5 ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIIVTLEDVIEEIIKSEILDETDLYAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVIDNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMLEHHHH 6n7e D 3.50 BS02 ANP D 1 T451 F457 Y478 T479 R480 I481 P482 L545 I566 T568 E570 D571 E584 Y588 T21 F27 Y48 T49 R50 I51 P52 L115 I126 T128 E130 D131 E144 Y148 Q9H8M5 ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVLLQVYIPDYSVRALSDLQFVKISRQQYQNALMLEHH 6n7e D 3.50 BS03 MG D 1 E570 E584 E130 E144 Q9H8M5 ELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVLLQVYIPDYSVRALSDLQFVKISRQQYQNALMLEHH 6n98 A 1.55 BS01 MG A 1 E179 E215 D243 D285 E176 E212 D240 D282 5.3.1.5 A0A1K2FZ20 FQPTPEDRFCFGLWTVGWQERDQFGEATRAPLDPVRTVHKLAELGAWGVTFHDDDLLAVEPNRDAAIAAFRKALDETGLVVPAATTDLFKHPVFKDGAFTSNDRDVRRHAIRKVMRNLDLAAELGAKTYVFWGGREGAESDAAKDVRVALDRFREAIDYLAGYVKEQNYGMRFALEPKPNEPRGDILLPTIGHALGFISTLEHHEMVGLNPEVGHEQMAGLNFVHGIAQALWQDKLFHIDLNGQHGPRYDQDLVFGHGDTKSAFFLVDLLESSGWEGPRHFDYKPGRTEDAEDVWVSAEANMRTYLILKERAKAFRADPEVQEAMRACRIEELAVPTIAAGESYEDLRAEEFDAEAARDRGYHYSRLNQLAVEHMLGSR 6n98 A 1.55 BS02 MG A 2 E215 H218 D253 D255 E212 H215 D250 D252 5.3.1.5 A0A1K2FZ20 FQPTPEDRFCFGLWTVGWQERDQFGEATRAPLDPVRTVHKLAELGAWGVTFHDDDLLAVEPNRDAAIAAFRKALDETGLVVPAATTDLFKHPVFKDGAFTSNDRDVRRHAIRKVMRNLDLAAELGAKTYVFWGGREGAESDAAKDVRVALDRFREAIDYLAGYVKEQNYGMRFALEPKPNEPRGDILLPTIGHALGFISTLEHHEMVGLNPEVGHEQMAGLNFVHGIAQALWQDKLFHIDLNGQHGPRYDQDLVFGHGDTKSAFFLVDLLESSGWEGPRHFDYKPGRTEDAEDVWVSAEANMRTYLILKERAKAFRADPEVQEAMRACRIEELAVPTIAAGESYEDLRAEEFDAEAARDRGYHYSRLNQLAVEHMLGSR 6n99 B 2.80 BS02 MG B 2 M88 E181 N215 D245 H285 D287 M86 E179 N213 D243 H283 D285 5.3.1.5 A0A1K2FKX8 YQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVETVQRLAELGAHGVTFHDDDLIPFGSSDAEREAHIKRFREALDATGMKVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAAELGAEVYVAWGGREGAESGAAKDVRAALDRMKEAFDILGEYVTAQGYNLRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRAAFWLVDLLESAGYEGPRHFDFKPPRTEDLDGVWASAAGCMRNYLILKERSAAFRADPEVQEALRAARLDQLAEPTAADGLQALLADRTAFEDFDVDAAAARGMAFERLDQLAMDHLLGA 6n99 C 2.80 BS01 MG C 1 K183 E217 H220 D255 D257 K181 E215 H218 D253 D255 5.3.1.5 A0A1K2FKX8 YQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVETVQRLAELGAHGVTFHDDDLIPFGSSDAEREAHIKRFREALDATGMKVPMATTNLFTHPVFKDGGFTANDRDVRRYALRKTIRNIDLAAELGAEVYVAWGGREGAESGAAKDVRAALDRMKEAFDILGEYVTAQGYNLRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRAAFWLVDLLESAGYEGPRHFDFKPPRTEDLDGVWASAAGCMRNYLILKERSAAFRADPEVQEALRAARLDQLAEPTAADGLQALLADRTAFEDFDVDAAAARGMAFERLDQLAMDHLLGA 6njs A 2.70 BS01 KQV A 1 R609 S611 E612 S613 T620 S636 V637 E638 P639 Y640 Q644 Y657 K658 I659 L666 R445 S447 E448 S449 T456 S472 V473 E474 P475 Y476 Q480 Y493 K494 I495 L502 P40763 31715132 VVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYC 6o3g L 3.65 BS01 III S 1 G92 T93 S94 S96 G93 T94 S95 S97 DVVMTQSPGTLSLSPGERATLSCRASQSVSGGALAWYQQKPGQAPRLLIYDTSSRPTGVPGRFSGSGSGTDFSLTISRLEPEDFAVYYCQQYGTSQSTFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6o3g H 3.65 BS01 III S 1 T31 L32 A33 N35 W47 G50 I51 V52 L53 I56 N58 E95 G100A K100B P100C R100E F100G T31 L32 A33 N35 W47 G50 I51 V52 L54 I57 N59 E99 G105 K106 P107 R109 F111 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSKSTTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o3g B 3.65 BS01 III I 1 Y91 G92 T93 S94 S96 Y92 G93 T94 S95 S97 DVVMTQSPGTLSLSPGERATLSCRASQSVSGGALAWYQQKPGQAPRLLIYDTSSRPTGVPGRFSGSGSGTDFSLTISRLEPEDFAVYYCQQYGTSQSTFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6o3g A 3.65 BS01 III I 1 L32 A33 N35 W47 G50 I51 V52 L53 I56 V57 N58 E95 W99 F100 G100A K100B P100C R100E L32 A33 N35 W47 G50 I51 V52 L54 I57 V58 N59 E99 W103 F104 G105 K106 P107 R109 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 6o3g C 3.65 BS01 III Q 1 T31 L32 A33 N35 G50 I51 V52 I56 N58 E95 W99 F100 G100A K100B P100C R100E T31 L32 A33 N35 G50 I51 V52 I57 N59 E99 W103 F104 G105 K106 P107 R109 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6o3g F 3.65 BS01 III G 1 G92 T93 S96 G93 T94 S97 DVVMTQSPGTLSLSPGERATLSCRASQSVSGGALAWYQQKPGQAPRLLIYDTSSRPTGVPGRFSGSGSGTDFSLTISRLEPEDFAVYYCQQYGTSQSTFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6o3g E 3.65 BS01 III G 1 L32 A33 N35 G50 I51 V52 L53 I56 N58 E95 F100 G100A K100B P100C R100E L32 A33 N35 G50 I51 V52 L54 I57 N59 E99 F104 G105 K106 P107 R109 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6o3j H 3.42 BS02 44E H 1 S30 T31 S30 T31 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o3j A 3.42 BS01 III I 1 T31 A33 N35 W47 G50 I51 V52 L53 I56 N58 E95 W99 F100 G100A K100B P100C R100E T31 A33 N35 W47 G50 I51 V52 L54 I57 N59 E99 W103 F104 G105 K106 P107 R109 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o3j A 3.42 BS02 44E A 1 T28 F29 S30 T28 F29 S30 EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGGIVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o3l H 1.98 BS01 III D 1 S31 Y32 A33 N35 W47 G50 I51 V52 S56 T57 N58 E95 F100 G100A R100B P100C R100E S31 Y32 A33 N35 W47 G50 I51 V52 S57 T58 N59 E99 F104 G105 R106 P107 R109 KVQLVQSGAELKKPWSSVRVSCKASGGSFSSYAFNWVRQAPGQRLEWLGGIVPLVSSTNYAQRFRGRVTISADRSTSTVYLEMTGLTSADTAVYFCAREGEGWFGRPLRAFEFWGQGTLVTVSTASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6o3u H 3.11 BS01 44E H 1 S28 F29 S30 S31 S28 F29 S30 S31 KVQLVQSGAELKKPWSSVRVSCKASGGSFSSYAFNWVRQAPGQRLEWLGGIVPLVSSTNYAQRFRGRVTISADRSTSTVYLEMTGLTSADTAVYFCAREGEGWFGRPLRAFEFWGQGTLVTVSTASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o3u H 3.11 BS02 44E H 2 D72 R73 S74 D73 R74 S75 KVQLVQSGAELKKPWSSVRVSCKASGGSFSSYAFNWVRQAPGQRLEWLGGIVPLVSSTNYAQRFRGRVTISADRSTSTVYLEMTGLTSADTAVYFCAREGEGWFGRPLRAFEFWGQGTLVTVSTASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o3u B 3.11 BS02 44E B 2 S28 F29 S30 S28 F29 S30 KVQLVQSGAELKKPWSSVRVSCKASGGSFSSYAFNWVRQAPGQRLEWLGGIVPLVSSTNYAQRFRGRVTISADRSTSTVYLEMTGLTSADTAVYFCAREGEGWFGRPLRAFEFWGQGTLVTVSTASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 6o42 L 2.60 BS01 III G 1 Y32 Y91 G92 T93 S94 S96 Y33 Y92 G93 T94 S95 S97 EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGTSQSTFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6o42 H 2.60 BS01 III G 1 S31 A33 G50 I51 I52 I53 F54 N58 E95 G100A K100B P100C R100E S31 A33 G50 I51 I52 I54 F55 N59 E99 G105 K106 P107 R109 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6o42 B 2.60 BS01 III I 1 S31 G50 I51 I52 F54 N58 E95 G100A K100B P100C R100E S31 G50 I51 I52 F55 N59 E99 G105 K106 P107 R109 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAREGEGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6o5h A 2.84 BS01 LNJ A 1 Q134 Q136 A137 Y267 W311 F314 F362 K364 L365 V367 L369 P374 Y378 V381 P382 Q131 Q133 A134 Y264 W308 F311 F359 K361 L362 V364 L366 P371 Y375 V378 P379 3.3.2.6 P09960 31751136 VDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 6o5h B 2.84 BS01 LNJ B 1 Q136 A137 Y267 W311 F314 K364 L365 V366 V367 L369 P374 Y378 P382 Q134 A135 Y265 W309 F312 K362 L363 V364 V365 L367 P372 Y376 P380 3.3.2.6 P09960 31751136 IVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 6o5h C 2.84 BS01 LNJ C 1 Q134 Q136 A137 Y267 W311 F314 F362 K364 L365 V367 L369 P374 A377 Y378 P382 Q132 Q134 A135 Y265 W309 F312 F360 K362 L363 V365 L367 P372 A375 Y376 P380 3.3.2.6 P09960 31751136 IVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 6o5y A 3.17 BS01 HEM A 1 R106 M121 S122 R135 I198 D313 L314 A317 G318 T321 V322 F376 F381 V382 T385 I386 H388 Q411 I449 F450 G451 R455 K456 C457 I458 G459 A463 R71 M86 S87 R100 I159 D265 L266 A269 G270 T273 V274 F328 F333 V334 T337 I338 H340 Q363 I401 F402 G403 R407 K408 C409 I410 G411 A415 1.14.14.1 P04798 31757797 GLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6o5y A 3.17 BS02 KUV A 1 F123 N221 N223 G225 V227 V228 F251 L254 L312 D313 G316 A317 T321 I386 L496 T497 F88 N182 N184 G186 V188 V189 F212 L215 L264 D265 G268 A269 T273 I338 L448 T449 1.14.14.1 P04798 31757797 GLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6o5y B 3.17 BS01 HEM B 1 R106 M121 S122 R135 I198 L314 G318 T321 V322 F376 F381 V382 T385 I386 H388 Q411 I449 F450 G451 R455 K456 C457 I458 G459 I462 A463 R70 M85 S86 R99 I156 L272 G276 T279 V280 F334 F339 V340 T343 I344 H346 Q369 I407 F408 G409 R413 K414 C415 I416 G417 I420 A421 1.14.14.1 P04798 31757797 LKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS 6ob5 B 2.21 BS02 FPP D 1 F133 Y197 L198 A201 F127 Y191 L192 A195 A0A2Y0TBT9 31754004 EGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVADGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIFALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTALVYLIAAKAMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 6ob5 A 2.21 BS01 MAL A 1 N12 D14 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 W340 N6 D8 W52 A53 D55 R56 E101 E143 P144 Y145 F146 W220 W330 A0A2Y0TBT9 31754004 LVIWINGDKGYNGLAEVGKKFEKGIKVTVEHPDKLEEKFPQVAGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIFALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTALVYLIAAKAMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 6ob5 D 2.21 BS01 FPP D 1 F81 L89 W114 A119 K122 F123 L152 F70 L78 W100 A105 K108 F109 L138 31754004 SDLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGFTPLGLAALWGHLEIVEVLLKHGNAMGSDGWTPLHAAAKFGYLEIVEVLLKHGADVNAQDKRGKTPFDLAIDNGNEDIAEVL 6om5 A 1.60 BS01 HEM A 1 K45 V51 A69 K72 Q74 M79 R82 W86 L90 A104 M106 M109 L112 T113 I115 M116 P117 H119 L122 L125 K25 V31 A49 K52 Q54 M59 R62 W66 L70 A84 M86 M89 L92 T93 I95 M96 P97 H99 L102 L105 31742788 HMQVVGNVSTDTNQTRYIKIKAGEKDGKAGVEIYDSSIPNDPAVLSKTANNKGQSFEKMAERADKWISHLTGVAKKDKNGVIVAKMNKMPNLTLIMPDHRGLGRLSFKQVGNQDTYFGEWENVDAATSAAKNVSVYYAGSDPTKTLPSGKATYTVEGINKYGNFNSRLMKGTFDVDFERASISGYLSKPNLSLSIESKIDKTNATFEGIAKAEGVIGKSEGRFYGAKAEGLAGMATFASKPEYNTAFGGTKN 6peb A 2.46 BS01 OE4 A 1 Y188 H191 F193 R196 D219 V242 A244 P273 S275 P307 I309 R311 I351 Y173 H176 F178 R181 D204 V227 A229 P258 S260 P292 I294 R296 I336 2.4.2.12 P43490 31749905 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNI 6peb B 2.46 BS02 OE4 B 1 H191 F193 R196 D219 V242 A244 P273 S275 P307 R311 I351 A379 H175 F177 R180 D203 V226 A228 P257 S259 P291 R295 I335 A363 2.4.2.12 P43490 31749905 AEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNI 6pek A 4.20 BS01 III G 1 Y415 V416 G453 H455 Y93 V94 G131 H133 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek A 4.20 BS02 ADP A 1 A345 P384 G385 N386 G387 K388 T389 M390 L517 G546 S547 T550 A23 P62 G63 N64 G65 K66 T67 M68 L190 G219 S220 T223 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek A 4.20 BS03 BEF A 1 P384 G385 K388 N487 P62 G63 K66 N160 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek A 4.20 BS04 MG A 1 T389 D441 T67 D119 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek B 4.20 BS01 III G 1 K414 Y415 V416 H455 K92 Y93 V94 H133 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek B 4.20 BS02 BEF A 1 R498 R499 R176 R177 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek B 4.20 BS03 ADP B 1 A345 G385 N386 G387 T389 M390 L517 G546 S547 T550 A23 G63 N64 G65 T67 M68 L195 G224 S225 T228 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek C 4.20 BS01 III G 1 K414 Y415 V416 H455 A457 K92 Y93 V94 H133 A135 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek C 4.20 BS02 ADP B 1 D470 R498 D148 R176 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek C 4.20 BS04 ADP C 1 D343 A345 G385 N386 G387 K388 T389 M390 L517 G546 S547 T550 D21 A23 G63 N64 G65 K66 T67 M68 L195 G224 S225 T228 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek C 4.20 BS05 BEF C 1 P383 P384 G385 K388 P61 P62 G63 K66 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek D 4.20 BS04 ADP D 1 D343 A345 G385 N386 G387 K388 T389 M390 G546 D26 A28 G68 N69 G70 K71 T72 M73 G229 5.6.1.1 Q9UBP0 RNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKD 6pek E 4.20 BS01 III G 1 K414 V416 K92 V94 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMYSGSDLTALAKSPQTLEAYIRWNKD 6pek E 4.20 BS03 ADP E 1 I344 P384 G385 N386 G387 K388 T389 M390 L517 G546 I22 P62 G63 N64 G65 K66 T67 M68 L195 G221 5.6.1.1 Q9UBP0 NLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMYSGSDLTALAKSPQTLEAYIRWNKD 6peq A 2.97 BS01 ZK1 A 1 Y405 Y450 P478 L479 T480 R485 G653 S654 Y732 Y15 Y60 P88 L89 T90 R95 G217 S218 Y296 P19491 ENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6peq A 2.97 BS02 CLR E 1 Y797 G804 Y353 G360 P19491 ENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6peq B 2.97 BS01 ZK1 B 1 Y405 Y450 P478 L479 T480 R485 G653 S654 T686 Y732 Y12 Y57 P85 L86 T87 R92 G214 S215 T247 Y293 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6peq B 2.97 BS02 CLR F 1 Y797 M807 Y349 M359 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6peq E 2.97 BS01 CLR E 1 M11 L14 V15 A18 L157 M10 L13 V14 A17 L129 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 6peq F 2.97 BS01 CLR F 1 L14 V15 A18 M153 L157 L13 V14 A17 M128 L132 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVS 6peq H 2.97 BS01 CLR H 1 M11 V15 A18 L157 M10 V14 A17 L132 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVS 6pu7 A 2.43 BS01 HEM A 1 Y126 F163 S167 V170 F214 F226 A264 G265 F270 F291 R343 H346 I349 V350 Y353 I354 L384 F387 L388 V391 Y117 F154 S158 V161 F205 F217 A255 G256 F261 F282 R334 H337 I340 V341 Y344 I345 L358 F361 L362 V365 1.13.11.52 P14902 31749906 MISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQTGGTDLMNFLKTVRSTTEKSLLK 6pu7 A 2.43 BS02 OY4 A 1 Y126 C129 V130 F163 S167 F226 R231 L234 G262 S263 A264 G265 Y117 C120 V121 F154 S158 F217 R222 L225 G253 S254 A255 G256 1.13.11.52 P14902 31749906 MISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQTGGTDLMNFLKTVRSTTEKSLLK 6pwc R 4.90 BS01 III B 1 V223 T225 W334 V175 T177 W263 P30989 APSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCHTLSSNATRET 6pwh A 1.75 BS01 VRD A 1 L2 L5 G6 I9 A19 Y22 G23 N28 C29 G30 C45 H48 K49 Y52 L2 L5 G6 I9 A18 Y21 G22 N27 C28 G29 C44 H47 K48 Y51 Q9I834 31748642 SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC 6pyj A 1.44 BS01 III C 1 Y7 H9 T24 E45 Y59 R62 E63 I66 C67 E76 D77 L81 Y84 L95 Y99 D116 Y123 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171 Y7 H9 T24 E45 Y59 R62 E63 I66 C67 E76 D77 L81 Y84 L95 Y99 D116 Y123 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171 P01889 31740583 GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAPWIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYGCDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6pzf A 2.80 BS01 CA A 1 D293 G297 D324 N344 N347 G348 D213 G217 D244 N263 N266 G267 3.2.1.18 31757767 RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVHNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGPATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCRDNWQGSNRPVVQIDPVAMTHTSQYICSPVLTDSPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL 6qun O 3.00 BS01 NAD O 1 N6 G7 F8 G9 R10 I11 N31 D32 P33 R77 S95 T96 G97 F99 S119 A120 C149 A180 N313 N7 G8 F9 G10 R11 I12 N32 D33 P34 R80 S98 T99 G100 F102 S122 A123 C152 A183 N316 1.2.1.12 P25858 31772010 KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA 6qun R 3.00 BS01 NAD R 1 N6 G7 G9 R10 I11 N31 D32 P33 F34 S95 T96 G97 F99 S119 A120 C149 A180 N313 E314 Y317 N7 G8 G10 R11 I12 N32 D33 P34 F35 S98 T99 G100 F102 S122 A123 C152 A183 N316 E317 Y320 1.2.1.12 P25858 31772010 KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA 6quq O 2.99 BS01 NAD O 1 N6 G7 F8 G9 R10 I11 N31 D32 P33 F34 R77 S95 T96 G97 F99 S119 A120 A180 N313 Y317 N6 G7 F8 G9 R10 I11 N31 D32 P33 F34 R79 S97 T98 G99 F101 S121 A122 A182 N315 Y319 1.2.1.12 P25858 31772010 IRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA 6quq O 2.99 BS02 GSH O 1 A120 P121 S148 C149 T150 T174 H176 S206 S207 T208 S229 R231 A122 P123 S150 C151 T152 T176 H178 S208 S209 T210 S231 R233 1.2.1.12 P25858 31772010 IRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA 6quq R 2.99 BS01 NAD R 1 N6 G7 F8 G9 R10 I11 N31 D32 P33 F34 I35 R77 S95 T96 G97 S119 A120 A180 N313 E314 Y317 N7 G8 F9 G10 R11 I12 N32 D33 P34 F35 I36 R80 S98 T99 G100 S122 A123 A183 N316 E317 Y320 1.2.1.12 P25858 31772010 KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA 6quq R 2.99 BS02 GSH R 1 P121 S148 C149 H176 S206 S207 T208 S229 R231 N313 P124 S151 C152 H179 S209 S210 T211 S232 R234 N316 1.2.1.12 P25858 31772010 KIRIGINGFGRIGRLVARVVLQRDDVELVAVNDPFITTEYMTYMFKYDSVHGQWKHNELKIKDEKTLLFGEKPVTVFGIRNPEDIPWAEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEHEYKSDLDIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHSITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKAATYDEIKKAIKEESEGKLKGILGYTEDDVVSTDFVGDNRSSIFDAKAGIALSDKFVKLVSWYDNEWGYSSRVVDLIVHMSKA 6qxz A BS01 III B 1 S851 A854 S855 V856 G857 S858 E859 F860 T861 E862 S863 A864 W865 V866 R867 D869 W874 R876 I885 E887 S889 I915 N916 E918 L919 I921 Q923 S2 A5 S6 V7 G8 S9 E10 F11 T12 E13 S14 A15 W16 V17 R18 D20 W25 R27 I36 E38 S40 I66 N67 E69 L70 I72 Q74 2.1.1.43 Q2LAE1 GSRRASVGSEFTESAWVRCDDCFKWRRIPASVVGSIDESSRWICMNNSDKRFADCSKSQEMSNEEINEELGIGQDEADA 6rop A 2.70 BS01 OCA A 1 S112 A160 C161 F200 F395 S112 A160 C161 F200 F395 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 P19096 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 6rop B 2.70 BS01 OCA B 1 S112 A160 C161 F200 Y222 G394 F395 S112 A160 C161 F200 Y222 G394 F395 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 P19096 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGLAFHSYFMEGIAPTLLQALKKRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 6rop C 2.70 BS01 OCA C 1 S112 A160 C161 F200 G394 F395 S112 A160 C161 F200 G394 F395 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 P19096 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFARTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 6rop D 2.70 BS01 OCA D 1 S112 A160 C161 F200 Y222 G394 F395 S112 A160 C161 F200 Y222 G394 F395 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 P19096 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 6rop D 2.70 BS02 OCA D 2 S581 V639 P640 A641 N738 V740 P742 V743 S581 V639 P640 A641 N738 V740 P742 V743 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 P19096 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 6rop D 2.70 BS03 CO8 D 1 M499 H580 S581 L582 M620 A622 G624 C642 N644 D647 T648 T650 F671 K673 V675 L680 F686 L739 L766 V770 R773 M499 H580 S581 L582 M620 A622 G624 C642 N644 D647 T648 T650 F671 K673 V675 L680 F686 L739 L766 V770 R773 2.3.1.85,2.3.1.38,2.3.1.39,2.3.1.41,1.1.1.100,4.2.1.59,1.3.1.39 P19096 SEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPN 6rq4 A 1.96 BS01 KE8 A 1 I31 E33 G34 Y36 G37 V39 A52 K54 Q105 D106 M108 E109 D111 K114 N154 L156 C166 D167 I13 E15 G16 Y18 G19 V21 A34 K36 Q87 D88 M90 E91 D93 K96 N136 L138 C148 D149 2.7.11.24 P28482 31748345 FDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFPKEKLKELIFEETARFQPG 6s6y A 3.10 BS01 MFN A 1 H229 L233 H258 F261 T308 S310 F343 Y345 Q355 D377 N380 H229 L233 H258 F261 T308 S310 F343 Y345 Q355 D377 N380 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPENPMTGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y A 3.10 BS02 ZN A 1 H59 K176 H59 K176 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPENPMTGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y A 3.10 BS03 ZN A 2 K176 H229 H258 K176 H229 H258 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPENPMTGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y A 3.10 BS04 CA A 1 E398 E423 E398 E423 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPENPMTGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y A 3.10 BS05 CA A 2 S117 D334 S117 D334 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPENPMTGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y B 3.10 BS01 CA B 1 V63 E66 D217 R222 V62 E65 D216 R221 A9W3S0 AAWVKGGAADVDAAVEAAADLLAASRVPVLAGLSAEVSALRAAYRLAETLGASLDPVSGPSVYAELGALSAGGAMSTTRAETIGRADVILIVGNRPWDGELIAEIAAAAPSRGRAAGAERALLSLGGPQNGAIRHVAYAADAGGLTISLGHLRAFAKGHLAGEAAFADLAKRLFAAQYGVIVYDPEEVGELGAEMLQGLIRDLNESTRFFALTLADPFQGRAAVQLSAWTTGQAPRVGFGRHQPEHDSWRFDSARQIAAGEADAALWLASLPAPRPAWLGSLPTIAIVGEGSQEAAGETAEVVITVGVPGQSVGGALWNDRRGVIAYAEASDPAETETAAGVLTRIRDRLIEKGVS 6s6y B 3.10 BS02 DGL B 1 R154 R202 R153 R201 A9W3S0 AAWVKGGAADVDAAVEAAADLLAASRVPVLAGLSAEVSALRAAYRLAETLGASLDPVSGPSVYAELGALSAGGAMSTTRAETIGRADVILIVGNRPWDGELIAEIAAAAPSRGRAAGAERALLSLGGPQNGAIRHVAYAADAGGLTISLGHLRAFAKGHLAGEAAFADLAKRLFAAQYGVIVYDPEEVGELGAEMLQGLIRDLNESTRFFALTLADPFQGRAAVQLSAWTTGQAPRVGFGRHQPEHDSWRFDSARQIAAGEADAALWLASLPAPRPAWLGSLPTIAIVGEGSQEAAGETAEVVITVGVPGQSVGGALWNDRRGVIAYAEASDPAETETAAGVLTRIRDRLIEKGVS 6s6y C 3.10 BS01 GLU C 1 I178 R197 R198 I177 R196 R197 A9W3R7 STLRLRGDLPERVDLLNITPLALSGLSETEAGKLAIGTSRRGLTLGDVFEIRLDGSDSLVIEGGSARLDRVGAALSQGSIRVEGDVGQRLGEGMAAGTLTVTGSAGPYAGTGATGGTITIEGDAGDHAGGAVYAAKAGLDGATLVIKGAAGDHLGDRMRRGMILAGSAGAFAASRMIAGTIVVSGALGDHPGYGMRRGTLIAGSHGTLLPTFVETGTPDLVFVRLLAQSLKHLGAAQANLLSGTLRRYSGDLATLGKGELFVPAH 6s6y C 3.10 BS02 IAS D 1 R160 R161 A179 R159 R160 A178 A9W3R7 STLRLRGDLPERVDLLNITPLALSGLSETEAGKLAIGTSRRGLTLGDVFEIRLDGSDSLVIEGGSARLDRVGAALSQGSIRVEGDVGQRLGEGMAAGTLTVTGSAGPYAGTGATGGTITIEGDAGDHAGGAVYAAKAGLDGATLVIKGAAGDHLGDRMRRGMILAGSAGAFAASRMIAGTIVVSGALGDHPGYGMRRGTLIAGSHGTLLPTFVETGTPDLVFVRLLAQSLKHLGAAQANLLSGTLRRYSGDLATLGKGELFVPAH 6s6y D 3.10 BS01 DGL D 1 R124 W147 R123 W146 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6s6y D 3.10 BS02 IAS D 1 R135 R145 R134 R144 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6s6y I 3.10 BS01 L6K I 1 H229 L233 G234 H258 F261 T308 V351 Q355 D377 N380 H229 L233 G234 H258 F261 T305 V348 Q352 D374 N377 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPETGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y I 3.10 BS04 DGL I 1 K326 W328 K323 W325 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPETGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y J 3.10 BS01 GLU J 1 G73 R154 R202 G72 R153 R201 A9W3S0 AAWVKGGAADVDAAVEAAADLLAASRVPVLAGLSAEVSALRAAYRLAETLGASLDPVSGPSVYAELGALSAGGAMSTTRAETIGRADVILIVGNRPWDGELIAEIAAAAPSRGRAAGAERALLSLGGPQNGAIRHVAYAADAGGLTISLGHLRAFAKGHLAGEAAFADLAKRLFAAQYGVIVYDPEEVGELGAEMLQGLIRDLNESTRFFALTLADPFQGRAAVQLSAWTTGQAPRVGFGRHQPEHDSWRFDSARQIAAGEADAALWLASLPAPRPAWLGSLPTIAIVGEGSQEAAGETAEVVITVGVPGQSVGGALWNDRRGVIAYAEASDPETETAAGVLTRIRDRLIEKGVS 6s6y K 3.10 BS03 DGL L 1 R160 R161 G180 R159 R160 G179 A9W3R7 STLRLRGDLPERVDLLNITPLALSGLSETEAGKLAIGTSRRGLTLGDVFEIRLDGSDSLVIEGGSARLDRVGAALSQGSIRVEGDVGQRLGEGMAAGTLTVTGSAGPYAGTGATGGTITIEGDAGDHAGGAVYAAKAGLDGATLVIKGAAGDHLGDRMRRGMILAGSAGAFAASRMIAGTIVVSGALGDHPGYGMRRGTLIAGSHGTLLPTFVETGTPDLVFVRLLAQSLKHLGAAQANLLSGTLRRYSGDLATLGKGELFVPAH 6s6y L 3.10 BS01 CA L 1 D60 K196 D59 K195 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6s6y L 3.10 BS02 DGL L 2 R124 A133 W147 R123 A132 W146 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6s6y L 3.10 BS03 DGL L 1 A133 K134 R135 R145 A132 K133 R134 R144 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6s6y M 3.10 BS01 ZN M 1 H59 K176 S310 L311 H59 K176 S308 L309 A9W3R9 MLTRIHGGRVVDPTAGRDAVGDVWIEDGRVVAPSERAPDQTIDATGCVVMAGGVEVHSHIAGGNVVMSRLLLPDLYVSESAPNGHPFAHAGGSGSWIGANYARMGYTTAVEPALPPSNALATHLELADIPLLDRGGLAVLGNDDHLLQLLRDGEGKQAVRDLVQQTLAHSRGLGVKCINAGGASAFKDGVLKLSLDDEIPCYGLSTRKIMSALLDAVEEIGVPHPLHVHCNNLGLPGADDSLVATLEAAEGRRIHFAHAQFYAYGVVDPEMTGGFRSAAERINAAMEAHPNATYDVGQVVFGQTVTISLDILRQFGGRKGAKPKKWVISAGDAEGGGVVPFLYRPRGPVSSLQWAIGLELMLLSSNPERTILTTDHPNGGVFTEYPRIIHLLMDAEERAKEIATLPAIVGERSGLPKIEREYSFSEIAQLTRSGPAKLLGLTDRGHLREGAKADVAIYRDDTDRTAMFSRAKLVLKDGQPIVEDGEVVAWFSGKTLSLNVEADAGMEKRAESYLQDRFGAGLDTFAVPDAAFPENTGTFEDVACRA 6s6y O 3.10 BS02 DGL P 1 R198 K258 R197 K257 A9W3R7 STLRLRGDLPERVDLLNITPLALSGLSETEAGKLAIGTSRRGLTLGDVFEIRLDGSDSLVIEGGSARLDRVGAALSQGSIRVEGDVGQRLGEGMAAGTLTVTGSAGPYAGTGATGGTITIEGDAGDHAGGAVYAAKAGLDGATLVIKGAAGDHLGDRMRRGMILAGSAGAFAASRMIAGTIVVSGALGDHPGYGMRRGTLIAGSHGTLLPTFVETGTPDLVFVRLLAQSLKHLGAAQANLLSGTLRRYSGDLATLGKGELFVPAH 6s6y P 3.10 BS01 CA L 2 K34 W35 K33 W34 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6s6y P 3.10 BS03 IAS P 1 A133 R135 R145 A132 R134 R144 2.3.1.101 A9W3R8 SDFTLNGIKVEDTFAEAFDVAGTAIIVTNDTPKWAMIAATVMTGFATSVIGCGAEAGIDAELSPDETPDGRPGVRILLFGFEPNGLKDQLLKRVGQCILTCPGTACFAGVEGPTKIKLGGAIRYFGDGFAVAKRLPDHEGKMRRYWRIPVMDGEFLCEDSVRAVDGAVGGGNLLFLGRKHADTLIVAEIAVEAAKAIPGAILPFPGGIVRSGSKVGGRTKGMMASTNDAYCPTLKGRAGSALPPECGVVLEIVIDALTSAAVAESMRAALHAATEIGAQHGLVAVTAGNYGGNLGRHHYHLRDLLEKP 6sis A 3.50 BS01 LFE D 1 W374 P375 V380 A384 L385 G386 L387 N433 H437 E438 V439 M442 W26 P27 V32 A36 L37 G38 L39 N85 H89 E90 V91 M94 O60885 31746102 KVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPD 6sis D 3.50 BS01 LFE D 1 W88 Y98 P99 L101 R107 I109 H110 S111 Y112 H115 W117 W28 Y38 P39 L41 R47 I49 H50 S51 Y52 H55 W57 P40337 31746102 PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQ 6st3 A 2.43 BS01 LUW A 1 R252 W258 T296 M299 Y303 Y310 H313 D315 D320 R322 H374 V376 W389 F391 R57 W63 T101 M104 Y108 Y115 H118 D120 D125 R127 H179 V181 W194 F196 1.14.11.29 Q9GZT9 31751494 PALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLT 6sup A 2.00 BS01 MG A 1 L670 R715 S716 H744 L639 R684 S685 H713 3.6.5.2 P60953 31748551 GPDGMAALSLPLPISAGRGYAPAFTLNYNSGAGNSPFGLGWDCNVMTIRRRTHFGVPHYDETDTFLGPEGEVLVVADQPRDESTLQGINLGATFTVTGYRSRLESHFSRLEYWQPKTTGKTDFWLIYSPDGQVHLLGKSPQARISNPSQTTQTAQWLLEASVSSRGEQIYYQYRAEDDTGCEADEITHHLQATAQRYLHIVYYGNRTASETLPGLDGSAPSQADWLFYLVFDYGERSNNLKTPPAFSTTGSWLCRQDRFSRYEYGFEIRTRRLCRQVLMYHHLQALDSKITEHNGPTLVSRLILNYDESAIASTLVFVRRVGHEQDGNVVTLPPLELAYQDFSPRHHAHWQPMDVLANFNAIQRWQLVDLKGEGLPGLLYQDKGAWWYRSAQRLGEIGSDAVTWEKMQPLSVIPSLQSNASLVDINGDGQLDWVITGPGLRGYHSQRPDGSWTRFTPLNALPVEYTHPRAQLADLMGAGLSDLVLIGPKSVRLYANTRDGFAKGKDVVQSGDITLPVPGADPRKLVAFSDVLGSGQAHLVEVSATKVTCWPNLGRGRFGQPITLPGFSQPATEFNPAQVYLADLDGSGPTDLIYVHTNRLDIFLNKSGNGFAEPVTLRFPEGLRFDHTCQLQMADVQGLGVASLILSVPHMSPHHWRCDLTNMKPWLLNEMNNNMGVHHTLRYRSSSQFWLDEKAAALTTGQTPVCYLPFPIHTLWQTETEDEISGNKLVTTLRYARGAWDGREREFRGFGYVEQTDSHQLAQGNAPERTPPALTKNWYATGLPVIDNALSTEYWRDDQAFAGFSPRFTTWQDNKDVPLTPEDDNSRYWFNRALKGQLLRSELYGLDDSTNKHVPYTVTEFRSQVRRLQHTDSRYPVLWSSVVESRNYHYERIASDPQCSQNITLSSDRFGQPLKQLSVQYPRRQQPAINLYPDTLPDKLLANSYDDQQRQLRLTYQQSSWHHLTNNTVRVLGLPDSTRSDIFTYVAENVPAGGLNLELLSDKNSLIADDKPREYLGQQKTAYTDGQNTTPLQTPTRQALIAFTETTVFNQSTLSAFNGSIPSDKLSTTLEQAGYQQTNYLFPRTGEDKVWVAHHGYTDYGTAAQFWRPQKQSNTQLTGKITLIWDANYCVVVQTRDAAGLTTSAKYDWRFLTPVQLTDINDNQHLITLDALGRPITLRFWGTENGKMTGYSSPEKASFSPPSDVNAAIELKKPLPVAQCQVYAPESWMPVLSQKTFNRLAEQDWQKLYNARIITEDGRICTLAYRRWVQSQKAIPQLISLLNNGPRLPPHSLTLTTDRYDHDPEQQIRQQVVFSDGFGRLLQAAARHEAGMARQRNEDGSLIINVQHTENRWAVTGRTEYDNKGQPIRTYQPYFLNDWRYVSNDSARQEKEAYADTHVYDPIGREIKVITAKGWFRRTLFTPWFTVNEDENDTAAEVKKIDPKLYQKTPTVSVYDNRGLIIRNIDFHRTTANGDPDTRITRHQYDIHGHLNQSIDPRLYEAKQTNNTIKPNFLWQYDLTGNPLCTESIDAGRTVTLNDIEGRPLLTVTATGVIQTRQYETSSLPGRLLSVAEQTPEEKTSRITERLIWAGNTEAEKDHNLAGQCVRHYDTAGVTRLESLSLTGTVLSQSSQLLIDTQEANWTGDNETVWQNMLADDIYTTLSTFDATGALLTQTDAKGNIQRLAYDVAGQLNGSWLTLKGQTEQVIIKSLTYSAAGQKLREEHGNDVITEYSYEPETQRLIGIKTRRPSDTKVLQDLRYEYDPVGNVISIRNDAEATRFWHNQKVMPENTYTYDSLYQLISATGREMANIGQQSHQFPSPALPSDNNTYTNYTRTYTYDRGGNLTKIQHSSPATQNNYTTNITVSNRSNRAVLSTLTEDPAQVDALFDAGGHQNTLISGQNLNWNTRGELQQVTLVKRDKGANDDREWYRYSGDGRRMLKINEQQASNNAQTQRVTYLPNLELRLTQNSTATTEDLQVITVGEAGRAQVRVLHWESGKPEDIDNNQLRYSYDNLIGSSQLELDSEGQIISEEEYYPYGGTALWAARNQTEASYKTIRYSGKERDATGLYYYGYRYYQPWIGRWLSSDPAGTIDGLNLYRMVRNNPVTLLDPDGLNVFDEAILAALEP 6sup A 2.00 BS02 MG A 2 Y1016 V1017 Y985 V986 3.6.5.2 P60953 31748551 GPDGMAALSLPLPISAGRGYAPAFTLNYNSGAGNSPFGLGWDCNVMTIRRRTHFGVPHYDETDTFLGPEGEVLVVADQPRDESTLQGINLGATFTVTGYRSRLESHFSRLEYWQPKTTGKTDFWLIYSPDGQVHLLGKSPQARISNPSQTTQTAQWLLEASVSSRGEQIYYQYRAEDDTGCEADEITHHLQATAQRYLHIVYYGNRTASETLPGLDGSAPSQADWLFYLVFDYGERSNNLKTPPAFSTTGSWLCRQDRFSRYEYGFEIRTRRLCRQVLMYHHLQALDSKITEHNGPTLVSRLILNYDESAIASTLVFVRRVGHEQDGNVVTLPPLELAYQDFSPRHHAHWQPMDVLANFNAIQRWQLVDLKGEGLPGLLYQDKGAWWYRSAQRLGEIGSDAVTWEKMQPLSVIPSLQSNASLVDINGDGQLDWVITGPGLRGYHSQRPDGSWTRFTPLNALPVEYTHPRAQLADLMGAGLSDLVLIGPKSVRLYANTRDGFAKGKDVVQSGDITLPVPGADPRKLVAFSDVLGSGQAHLVEVSATKVTCWPNLGRGRFGQPITLPGFSQPATEFNPAQVYLADLDGSGPTDLIYVHTNRLDIFLNKSGNGFAEPVTLRFPEGLRFDHTCQLQMADVQGLGVASLILSVPHMSPHHWRCDLTNMKPWLLNEMNNNMGVHHTLRYRSSSQFWLDEKAAALTTGQTPVCYLPFPIHTLWQTETEDEISGNKLVTTLRYARGAWDGREREFRGFGYVEQTDSHQLAQGNAPERTPPALTKNWYATGLPVIDNALSTEYWRDDQAFAGFSPRFTTWQDNKDVPLTPEDDNSRYWFNRALKGQLLRSELYGLDDSTNKHVPYTVTEFRSQVRRLQHTDSRYPVLWSSVVESRNYHYERIASDPQCSQNITLSSDRFGQPLKQLSVQYPRRQQPAINLYPDTLPDKLLANSYDDQQRQLRLTYQQSSWHHLTNNTVRVLGLPDSTRSDIFTYVAENVPAGGLNLELLSDKNSLIADDKPREYLGQQKTAYTDGQNTTPLQTPTRQALIAFTETTVFNQSTLSAFNGSIPSDKLSTTLEQAGYQQTNYLFPRTGEDKVWVAHHGYTDYGTAAQFWRPQKQSNTQLTGKITLIWDANYCVVVQTRDAAGLTTSAKYDWRFLTPVQLTDINDNQHLITLDALGRPITLRFWGTENGKMTGYSSPEKASFSPPSDVNAAIELKKPLPVAQCQVYAPESWMPVLSQKTFNRLAEQDWQKLYNARIITEDGRICTLAYRRWVQSQKAIPQLISLLNNGPRLPPHSLTLTTDRYDHDPEQQIRQQVVFSDGFGRLLQAAARHEAGMARQRNEDGSLIINVQHTENRWAVTGRTEYDNKGQPIRTYQPYFLNDWRYVSNDSARQEKEAYADTHVYDPIGREIKVITAKGWFRRTLFTPWFTVNEDENDTAAEVKKIDPKLYQKTPTVSVYDNRGLIIRNIDFHRTTANGDPDTRITRHQYDIHGHLNQSIDPRLYEAKQTNNTIKPNFLWQYDLTGNPLCTESIDAGRTVTLNDIEGRPLLTVTATGVIQTRQYETSSLPGRLLSVAEQTPEEKTSRITERLIWAGNTEAEKDHNLAGQCVRHYDTAGVTRLESLSLTGTVLSQSSQLLIDTQEANWTGDNETVWQNMLADDIYTTLSTFDATGALLTQTDAKGNIQRLAYDVAGQLNGSWLTLKGQTEQVIIKSLTYSAAGQKLREEHGNDVITEYSYEPETQRLIGIKTRRPSDTKVLQDLRYEYDPVGNVISIRNDAEATRFWHNQKVMPENTYTYDSLYQLISATGREMANIGQQSHQFPSPALPSDNNTYTNYTRTYTYDRGGNLTKIQHSSPATQNNYTTNITVSNRSNRAVLSTLTEDPAQVDALFDAGGHQNTLISGQNLNWNTRGELQQVTLVKRDKGANDDREWYRYSGDGRRMLKINEQQASNNAQTQRVTYLPNLELRLTQNSTATTEDLQVITVGEAGRAQVRVLHWESGKPEDIDNNQLRYSYDNLIGSSQLELDSEGQIISEEEYYPYGGTALWAARNQTEASYKTIRYSGKERDATGLYYYGYRYYQPWIGRWLSSDPAGTIDGLNLYRMVRNNPVTLLDPDGLNVFDEAILAALEP 6sup A 2.00 BS03 MG A 3 R1524 Y1542 K1545 R1482 Y1500 K1503 3.6.5.2 P60953 31748551 GPDGMAALSLPLPISAGRGYAPAFTLNYNSGAGNSPFGLGWDCNVMTIRRRTHFGVPHYDETDTFLGPEGEVLVVADQPRDESTLQGINLGATFTVTGYRSRLESHFSRLEYWQPKTTGKTDFWLIYSPDGQVHLLGKSPQARISNPSQTTQTAQWLLEASVSSRGEQIYYQYRAEDDTGCEADEITHHLQATAQRYLHIVYYGNRTASETLPGLDGSAPSQADWLFYLVFDYGERSNNLKTPPAFSTTGSWLCRQDRFSRYEYGFEIRTRRLCRQVLMYHHLQALDSKITEHNGPTLVSRLILNYDESAIASTLVFVRRVGHEQDGNVVTLPPLELAYQDFSPRHHAHWQPMDVLANFNAIQRWQLVDLKGEGLPGLLYQDKGAWWYRSAQRLGEIGSDAVTWEKMQPLSVIPSLQSNASLVDINGDGQLDWVITGPGLRGYHSQRPDGSWTRFTPLNALPVEYTHPRAQLADLMGAGLSDLVLIGPKSVRLYANTRDGFAKGKDVVQSGDITLPVPGADPRKLVAFSDVLGSGQAHLVEVSATKVTCWPNLGRGRFGQPITLPGFSQPATEFNPAQVYLADLDGSGPTDLIYVHTNRLDIFLNKSGNGFAEPVTLRFPEGLRFDHTCQLQMADVQGLGVASLILSVPHMSPHHWRCDLTNMKPWLLNEMNNNMGVHHTLRYRSSSQFWLDEKAAALTTGQTPVCYLPFPIHTLWQTETEDEISGNKLVTTLRYARGAWDGREREFRGFGYVEQTDSHQLAQGNAPERTPPALTKNWYATGLPVIDNALSTEYWRDDQAFAGFSPRFTTWQDNKDVPLTPEDDNSRYWFNRALKGQLLRSELYGLDDSTNKHVPYTVTEFRSQVRRLQHTDSRYPVLWSSVVESRNYHYERIASDPQCSQNITLSSDRFGQPLKQLSVQYPRRQQPAINLYPDTLPDKLLANSYDDQQRQLRLTYQQSSWHHLTNNTVRVLGLPDSTRSDIFTYVAENVPAGGLNLELLSDKNSLIADDKPREYLGQQKTAYTDGQNTTPLQTPTRQALIAFTETTVFNQSTLSAFNGSIPSDKLSTTLEQAGYQQTNYLFPRTGEDKVWVAHHGYTDYGTAAQFWRPQKQSNTQLTGKITLIWDANYCVVVQTRDAAGLTTSAKYDWRFLTPVQLTDINDNQHLITLDALGRPITLRFWGTENGKMTGYSSPEKASFSPPSDVNAAIELKKPLPVAQCQVYAPESWMPVLSQKTFNRLAEQDWQKLYNARIITEDGRICTLAYRRWVQSQKAIPQLISLLNNGPRLPPHSLTLTTDRYDHDPEQQIRQQVVFSDGFGRLLQAAARHEAGMARQRNEDGSLIINVQHTENRWAVTGRTEYDNKGQPIRTYQPYFLNDWRYVSNDSARQEKEAYADTHVYDPIGREIKVITAKGWFRRTLFTPWFTVNEDENDTAAEVKKIDPKLYQKTPTVSVYDNRGLIIRNIDFHRTTANGDPDTRITRHQYDIHGHLNQSIDPRLYEAKQTNNTIKPNFLWQYDLTGNPLCTESIDAGRTVTLNDIEGRPLLTVTATGVIQTRQYETSSLPGRLLSVAEQTPEEKTSRITERLIWAGNTEAEKDHNLAGQCVRHYDTAGVTRLESLSLTGTVLSQSSQLLIDTQEANWTGDNETVWQNMLADDIYTTLSTFDATGALLTQTDAKGNIQRLAYDVAGQLNGSWLTLKGQTEQVIIKSLTYSAAGQKLREEHGNDVITEYSYEPETQRLIGIKTRRPSDTKVLQDLRYEYDPVGNVISIRNDAEATRFWHNQKVMPENTYTYDSLYQLISATGREMANIGQQSHQFPSPALPSDNNTYTNYTRTYTYDRGGNLTKIQHSSPATQNNYTTNITVSNRSNRAVLSTLTEDPAQVDALFDAGGHQNTLISGQNLNWNTRGELQQVTLVKRDKGANDDREWYRYSGDGRRMLKINEQQASNNAQTQRVTYLPNLELRLTQNSTATTEDLQVITVGEAGRAQVRVLHWESGKPEDIDNNQLRYSYDNLIGSSQLELDSEGQIISEEEYYPYGGTALWAARNQTEASYKTIRYSGKERDATGLYYYGYRYYQPWIGRWLSSDPAGTIDGLNLYRMVRNNPVTLLDPDGLNVFDEAILAALEP 6szj A 2.53 BS01 M5W A 1 S25 V32 A45 V46 K47 L79 I93 T95 E96 Y97 M98 G101 L153 A163 S21 V28 A41 V42 K43 L72 I86 T88 E89 Y90 M91 G94 L146 A156 2.7.11.1 O43353 31749904 AICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLGTIIYMPPENYEPGQSIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK 6szj B 2.53 BS01 CA B 1 Q308 K310 Q281 K283 2.7.11.1 O43353 31749904 AICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK 6szj B 2.53 BS02 M5W B 1 S25 A45 V46 K47 L79 I93 T95 E96 Y97 M98 G101 L153 A163 S21 A41 V42 K43 L69 I83 T85 E86 Y87 M88 G91 L143 A153 2.7.11.1 O43353 31749904 AICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK 6t6a A 2.80 BS01 MLW A 1 F170 A186 F238 E239 L294 D307 F36 A52 F104 E105 L160 D173 2.7.12.1 Q13627 31766108 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK 6t6a B 2.80 BS01 MLW B 1 F170 V173 A186 E239 L241 L294 F36 V39 A52 E105 L107 L160 2.7.12.1 Q13627 31766108 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK 6t6a C 2.80 BS01 MLW C 1 I165 F170 V173 A186 K188 V222 F238 E239 L294 V306 D307 I31 F36 V39 A52 K54 V88 F104 E105 L160 V172 D173 2.7.12.1 Q13627 31766108 VYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK 6tir A BS01 NAI A 1 R15 F18 T19 K20 Y22 N183 N185 R218 K236 V237 N238 L242 L262 R15 F18 T19 K20 Y22 N183 N185 R218 K236 V237 N238 L242 L262 P21796 MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQALE 6tzu A 1.80 BS01 MG A 1 S200 Y230 S198 Y228 4.3.3.7 Q9PPB4 31678256 KNIIIGAMTALITPFKNGKVDEQSYARLIKRQIENGIDAVVPVGTTGESATLTHEEHRTCIEIAVETCKGTKVKVLAGAGSAATHEAVGLAKFAKEHGADGILSVAPYYNKPTQQGLYEHYKAIAQSVDIPVLLYNVPGRTGCEISTDTIIKLFRDCENIYGVKEASGNIDKCVDLLAHEPRMMLISGEDAINYPILSNGGKGVISVTSNLLPDMISALTHFALDENYKEAKKINDELYNINKILFCESNPIPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEEVMKKYKIKGF 6u01 B 1.87 BS01 MG B 1 S189 G190 E191 D192 N195 V206 I207 S208 S187 G188 E189 D190 N193 V204 I205 S206 4.3.3.7 A0A2U0QMK8 31678256 KNIIIGAMTALITPFKNGKVDEQSYARLIKRQIENGIDAVVPVGTTGESATLTHEEHRTCIEIAVETCKGTKVKVLAGAGSDATHEAVGLAKFAKEHGADGILSVAPYYNKPTQQGLYEHYKAIAQSVDIPVLLYNVPGRTGCEISTDTIIKLFRDCENIYGVKEASGNIDKCVDLLAHEPRMMLISGEDAINYPILSNGGKGVISVTSNLLPDMISALTHFALDENYKEAKKINDELYNINKILFCESNPIPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEEVMKKYKIKGF 6u5m A 1.80 BS01 Q0S A 1 S223 P224 N225 Y228 L240 K250 F266 S267 V268 K272 W273 L288 Q289 S191 P192 N193 Y196 L208 K218 F234 S235 V236 K240 W241 L256 Q257 P61964 31724864 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 6u6w A 1.20 BS01 Q0Y A 1 S223 P224 N225 Y228 L240 K250 F266 S267 K272 W273 L288 S198 P199 N200 Y203 L215 K225 F241 S242 K247 W248 L263 P61964 31724864 TQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 6u8d H 1.81 BS01 NUC A 1 Y58 Y60 T61 R104 S105 Y106 Y107 S108 R109 Y55 Y57 T58 R101 S102 Y103 Y104 S105 R106 31765566 EVQLVESGGGLVQPGGSLRLSCAASGFYISSYSIHWVRQAPGKGLEWVASIYPSYGYTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARRYRSYYSRYGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6u8d L 1.81 BS01 NUC A 1 Y94 Y95 Y94 Y95 31765566 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSSYYPSTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6u8k D 2.75 BS01 NUC B 1 Y31 Y34 S35 S36 S55 S57 S58 S60 Y62 S102 R103 Y104 S105 R106 Y107 R108 R109 Y28 Y31 S32 S33 S52 S54 S55 S57 Y59 S99 R100 Y101 S102 R103 Y104 R105 R106 31765566 EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVASISPSSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSRYSRYRRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6u8k E 2.75 BS01 NUC B 1 Y92 S93 Y97 Y92 S93 Y97 31765566 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYSSSPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6u8k F 2.75 BS01 NUC C 1 Y34 S35 S36 S55 S57 S58 S60 Y62 S102 R103 Y104 S105 R106 Y107 R109 Y31 S32 S33 S52 S54 S55 S57 Y59 S99 R100 Y101 S102 R103 Y104 R106 31765566 EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVASISPSSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSRYSRYRRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6u8k L 2.75 BS01 NUC A 1 Y50 Y92 S93 Y97 Y50 Y92 S93 Y97 31765566 SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYSSSPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6u8l A 1.57 BS02 Q1S A 1 A47 S49 S50 A65 I90 S91 D92 F133 S175 Y191 Y260 C261 I305 A17 S19 S20 A35 I60 S61 D62 F103 S145 Y161 Y230 C231 I275 P61964 31724864 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 6uak A 2.01 BS01 SAH A 1 W7 L17 R21 G49 C50 G51 D72 M73 E74 F77 G97 D98 A99 H115 T116 F117 W4 L14 R18 G46 C47 G48 D69 M70 E71 F74 G94 D95 A96 H112 T113 F114 A0A3D0LE54 31532570 IKKWSVYFQNPEFLERTRMFLIQKELYPLVRNWCGVKDNVRLLDVGCGTGYFTRLLVSGDEDVSAVGIDMEEPFIEYAREKAEELGLPAEFIIGDALALPFEDNTFDIVTSHTFLTSVPDPEKAMSEMKRVVKPGGIISSVTAMNFMPACNNEGEYPEECTWVEDLKKEYMKIYTKYFSADPLETRIKGVKCSDVPKFFTGQGLKDVSLYPIGKVFTLSNAAVSDEDKLRYIELFYASEIKKLDAFMELDIGITEEDAERFRSLIGQKCKWLRDHLHDNYAWEWQGGANLLVTGICN 6ucb A 3.28 BS01 ZK1 A 1 Y450 P478 L479 T480 R485 G653 S654 T686 Y732 Y57 P85 L86 T87 R92 G214 S215 T247 Y293 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ucb A 3.28 BS02 CLR E 1 Y797 G801 G804 Y351 G355 G358 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ucb B 3.28 BS01 ZK1 B 1 Y450 P478 L479 T480 R485 G653 S654 T686 M708 Y732 Y57 P85 L86 T87 R92 G214 S215 T247 M269 Y293 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ucb B 3.28 BS02 CLR B 1 G801 G804 L808 G355 G358 L362 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ucb E 3.28 BS01 CLR E 1 M11 L14 V15 A18 M153 L157 M10 L13 V14 A17 M125 L129 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 6ucb D 3.28 BS01 CLR H 1 Y797 G801 G804 L808 Y351 G355 G358 L362 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud2 A 1.70 BS01 Q4D A 1 H224 A227 F228 G230 M231 V249 M250 V253 R263 T266 L267 F270 G271 L290 I294 H53 A56 F57 G59 M60 V78 M79 V82 R92 T95 L96 F99 G100 L119 I123 Q07820 31736296 DELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEG 6ud4 A 3.30 BS01 ZK1 A 1 E402 Y405 Y450 P478 L479 T480 R485 G653 S654 T686 E9 Y12 Y57 P85 L86 T87 R92 G214 S215 T247 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud4 A 3.30 BS02 CLR A 1 Y797 V800 G801 G804 L808 Y351 V354 G355 G358 L362 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud4 B 3.30 BS01 ZK1 B 1 E402 Y450 P478 L479 T480 R485 G653 S654 T686 Y732 E9 Y57 P85 L86 T87 R92 G214 S215 T247 Y293 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud4 B 3.30 BS02 CLR F 1 Y797 V800 G801 G804 Y351 V354 G355 G358 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud4 E 3.30 BS01 CLR A 1 M11 A18 M153 L157 M10 A17 M125 L129 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 6ud4 F 3.30 BS01 CLR F 1 M11 L14 A18 M153 L157 M10 L13 A17 M128 L132 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVS 6ud4 C 3.30 BS01 CLR G 1 Y797 G804 L808 Y351 G358 L362 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud4 D 3.30 BS01 CLR H 1 Y797 V800 G804 Y351 V354 G358 P19491 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR 6ud8 E 3.20 BS01 CLR E 1 M11 L14 V15 A18 M10 L13 V14 A17 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS 6ud8 F 3.20 BS01 CLR F 1 L14 V15 F146 M153 L157 L13 V14 F121 M128 L132 Q6ZWS4 AFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVS 6udu A 1.75 BS01 Q4Y A 1 H224 A227 L235 V249 M250 V253 R263 T266 L267 F270 G271 L290 I294 H54 A57 L65 V79 M80 V83 R93 T96 L97 F100 G101 L120 I124 Q07820 31736296 EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEG 6ufn A 2.70 BS01 Q6M A 1 A24 D94 P134 H136 H137 G145 F146 D174 H176 W205 D267 E274 E304 G305 Y307 A24 D94 P134 H136 H137 G145 F146 D174 H176 W205 D267 E274 E304 G305 Y307 3.5.1.48,3.5.1.62 F1QCV2 31746596 AASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSETNIVWPEPLKRMPASVRTVVVPPPGVELTLPKNCQHSDISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLTLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETARLMRVWGHMTCLIQGLARGRMLTLLQGYDKDLLELTVSALSGASISPLGPRAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6uh3 A 2.70 BS01 RET A 1 W105 Y108 S111 S112 M115 M141 I142 G145 F206 F209 A210 Y233 S237 K241 W97 Y100 S103 S104 M107 M133 I134 G137 F198 F201 A202 Y225 S229 K233 A0A2R4S913 TVKEIKSLQNFNRIAGVFHLLQMLAVLALANDFALPMTGTYLNGPPGTTFSAPVVILETPVGLAVALFLGLSALFHFIVSSGNFFKRYSKNQNIFRWVEYSLSSSVMIVLIAQICGIADIVALLAIFGVNASMILFGWLQEKYTQPKDGDLLPFWFGCIAGIVPWIGLLIYVIAPGSTSDVAVPGFVYGIIISLFLFFNSFALVQYLQYKGKGKWSNYLRGERAYIVLSLVAKSALAWQIFSGTLI 6uh3 B 2.70 BS01 RET B 1 Y108 S112 M115 M141 I142 G145 F162 G165 C166 F206 F209 A210 Q213 K241 Y100 S104 M107 M133 I134 G137 F154 G157 C158 F198 F201 A202 Q205 K233 A0A2R4S913 TVKEIKSLQNFNRIAGVFHLLQMLAVLALANDFALPMTGTYLNGPPGTTFSAPVVILETPVGLAVALFLGLSALFHFIVSSGNFFKRYSKNQNIFRWVEYSLSSSVMIVLIAQICGIADIVALLAIFGVNASMILFGWLQEKYTQPKDGDLLPFWFGCIAGIVPWIGLLIYVIAPGSTSDVAVPGFVYGIIISLFLFFNSFALVQYLQYKGKGKWSNYLRGERAYIVLSLVAKSALAWQIFSGTL 6uhu A 2.80 BS01 Q7V A 1 A24 I27 D94 P134 H136 H137 G145 F146 D174 H176 W205 D267 E274 E304 G305 Y307 A24 I27 D94 P134 H136 H137 G145 F146 D174 H176 W205 D267 E274 E304 G305 Y307 F1QCV2 31746596 AASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAIVWPEPLKRMPASVRTVVVPPPGVELTLPKNCQHSDISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLTLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETTRLMRVWGHMTCLIQGLARGRMLTLLQGYDKDLLELTVSALSGASISPLGRAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6uhv A 2.53 BS01 XS6 A 1 D94 H136 H137 F146 D174 H176 W205 D267 E274 Y307 D94 H136 H137 F146 D174 H176 W205 D267 E274 Y307 3.5.1.48,3.5.1.62 F1QCV2 31746596 AASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKSVRTVVVPPPGVELTLPKNCQHSISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLTLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETARVWGHMTCLIQGLARGRMLTLLQGYDKDLLELTVSALSGASISPLGPLRAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6uii A 2.65 BS01 SS9 A 1 A24 D94 H136 H137 F146 D174 H176 W205 D267 E274 G305 F307 A24 D94 H136 H137 F146 D174 H176 W205 D267 E274 G305 F307 3.5.1.48,3.5.1.62 F1QCV2 31746596 AASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGFNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSVRTVVVPPPGVELTLPKNCQHSISESTAKEVQRIRDKHFDLTDNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETDKCVNRLTLCLGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETLMRVWGHMTCLIQGLARGRMLTLLQGYDKDLLELTVSALSGASISPLGLRAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6uij A 2.90 BS01 SS9 A 1 A24 D94 H136 H137 F146 D174 H176 W205 D267 E274 G305 Y307 A24 D94 H136 H137 F146 D174 H176 W205 D267 E274 G305 Y307 3.5.1.48,3.5.1.62 F1QCV2 31746596 AASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSVRTVVVPPPGVELTLPKNCQHSISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTTEDKCVNRLTLCLRGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETRLMRVWGHMTCLIQGLARGRMLTLLQGYDKDLLELTVSALSGASISPLGPLRAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6uil A 2.85 BS01 FKS A 1 A24 D94 P134 H136 H137 F146 C147 D174 H176 W205 D267 E274 E304 G305 Y307 A23 D93 P133 H135 H136 F145 C146 D173 H175 W204 D266 E273 E303 G304 Y306 3.5.1.48,3.5.1.62 F1QCV2 31746596 ASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSVRTVVVPPPGVELTLPKNCQHSISESTAKEVQRIRDKHFDQNILRSLGNIISVLDRMMVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLTLCGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETRLMRVWGHMTCLIQGLARGRMLTLLQDKDLLELTVSALSGASISPLGPAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6uim A 2.75 BS01 Q7Y A 1 D94 H136 H137 G145 F146 D174 H176 F204 W205 E274 Y307 D94 H136 H137 G145 F146 D174 H176 F204 W205 E274 Y307 3.5.1.48,3.5.1.62 F1QCV2 31746596 AASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSVRTVVVPPPGVELTLPKNCQHSISESTAKEVQRIRDKHFTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLTLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVEETTRLMRVWGHMTCLIQGLARGRMLTLLQGYDKDLLELTVSALSGASISPLGPRAPKPEDVEMMEKQRQRLQERWGLLRCTVSESW 6ukj A 3.30 BS01 Y01 A 1 Y62 S65 I66 T344 V348 Y391 R392 N395 Y16 S19 I20 T289 V293 Y336 R337 N340 W7FI62 VFKLIFKEIKDNIFIYILSIIYLSVSVMNTIFAKRTLNKIGNYSFVTSETHNFICMIMFFIVYSLFGHRSFNLQFFAISMLDACSVILAFIGLTRTTGNIQSFVLQLSIPINMFFCFLILRYRYHLYNYLGAVIIVVTIALVEMKLSFETQEENSIIFNLVLISSLIPVCFSNMTREIVFKKYKIDILRLNAMVSFFQLFTSCLILPVYTLPFLKQLHLPYNEIWTNIKNGFACLFLGRNTVVENCGLGMAKLCDDCDGAWKTFALFSFFDICDNLITSYIIDKFSTMTYTIVSCIQGPALAIAYYFKFLAGDVVREPRLLDFVTLFGYLFGSIIYRVGNIILERKKMRN 6ul8 A 2.68 BS01 Q9J A 1 V32 A45 K47 E66 L70 L79 I93 T95 E96 Y97 M98 L153 D164 V28 A41 K43 E59 L63 L72 I86 T88 E89 Y90 M91 L146 D157 2.7.11.1,2.7.10.2 O43353 31749904 AISSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHILLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLCKWGTIIYMPPENYESIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK 6ul8 B 2.68 BS01 Q9J B 1 S25 V32 A45 K47 E66 L70 L79 I93 T95 E96 Y97 M98 G101 L153 D164 S21 V28 A41 K43 E56 L60 L69 I83 T85 E86 Y87 M88 G91 L143 D154 2.7.11.1,2.7.10.2 O43353 31749904 AISSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLCKWGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLK 6unz A 3.20 BS01 SF4 A 1 C133 Q134 D135 G214 A251 C252 C346 S347 A348 R350 K491 C113 Q114 D115 G194 A231 C232 C326 S327 A328 R330 K462 4.2.1.2 E9AE57 31743022 DASAVNADFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz B 3.20 BS01 SF4 B 1 C133 Q134 D135 G214 G216 S217 A251 C252 C346 A348 R350 K491 G515 C107 Q108 D109 G188 G190 S191 A225 C226 C320 A322 R324 K457 G481 4.2.1.2 E9AE57 31743022 ADFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDISVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz C 3.20 BS01 SF4 C 1 C133 Q134 D135 G214 G216 A250 A251 C252 C346 S347 A348 K491 C106 Q107 D108 G187 G189 A223 A224 C225 C319 S320 A321 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz D 3.20 BS01 SF4 D 1 C133 Q134 D135 G214 G216 S217 C252 C346 S347 A348 R350 K491 C106 Q107 D108 G187 G189 S190 C225 C319 S320 A321 R323 K453 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz E 3.20 BS01 SF4 E 1 C133 A251 C252 C346 A348 R350 K491 C105 A223 C224 C318 A320 R322 K454 4.2.1.2 E9AE57 31743022 FHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz F 3.20 BS01 SF4 F 1 C133 Q134 D135 G214 G216 S217 A251 C252 C346 S347 A348 C106 Q107 D108 G187 G189 S190 A224 C225 C319 S320 A321 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz G 3.20 BS01 SF4 G 1 C133 D135 S217 C252 C346 A348 C106 D108 S190 C225 C319 A321 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6unz H 3.20 BS01 SF4 H 1 C133 Q134 D135 G214 G216 S217 A251 C252 C346 S347 A348 R350 G515 C106 Q107 D108 G187 G189 S190 A224 C225 C319 S320 A321 R323 G478 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uo0 A 1.85 BS01 SF4 A 1 C133 Q134 D135 G214 G216 S217 A251 C252 C346 A348 P466 K491 C106 Q107 D108 G187 G189 S190 A224 C225 C319 A321 P430 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uo0 A 1.85 BS03 LMR A 2 N219 K220 Y222 R471 N192 K193 Y195 R435 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uo0 A 1.85 BS04 LMR B 1 H334 A336 H307 A309 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uo0 B 1.85 BS01 SF4 B 1 C133 Q134 D135 G214 G216 A251 C252 C346 S347 A348 P466 K491 C106 Q107 D108 G187 G189 A224 C225 C319 S320 A321 P430 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uo0 B 1.85 BS02 LMR B 1 Q134 D135 R173 G215 G216 R421 T467 T468 R471 K491 Q107 D108 R146 G188 G189 R385 T431 T432 R435 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uo2 A 1.65 BS02 TSN A 1 W78 S150 H192 H193 G201 F202 D230 H232 W261 D323 Y363 W18 S90 H132 H133 G141 F142 D170 H172 W201 D263 Y303 F8W4B7 31755702 TGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQT 6uo3 A 1.09 BS02 QCP A 1 H82 P83 S150 H192 H193 F202 D230 H232 W261 D323 K330 Y363 H25 P26 S93 H135 H136 F145 D173 H175 W204 D266 K273 Y306 F8W4B7 31755702 GSATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQ 6uo4 B 1.27 BS02 TSN B 1 S150 H192 H193 G201 F202 D230 H232 W261 D323 S90 H132 H133 G141 F142 D170 H172 W201 D263 F8W4B7 31755702 TGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGFNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQT 6uo5 A 1.44 BS01 QCP A 1 H82 S150 H193 G201 F202 D230 H232 W261 D323 K330 G361 F363 H23 S91 H134 G142 F143 D171 H173 W202 D264 K271 G302 F304 F8W4B7 31755702 ATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGFNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQT 6uo7 A 1.40 BS02 QCP A 1 H82 P83 S150 H192 H193 G201 F202 D230 H232 W261 D323 L330 Y363 H24 P25 S92 H134 H135 G143 F144 D172 H174 W203 D265 L272 Y305 F8W4B7 31755702 SATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPLGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQ 6uob A 1.58 BS01 PHE A 1 Y409 Q416 T417 Y350 Q357 T358 F8W4B7 31755702 ATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPLGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQT 6uoi A 1.95 BS01 F3S A 1 C133 Q134 G214 S217 A251 C252 C346 A348 R350 K491 G515 C108 Q109 G189 S192 A226 C227 C321 A323 R325 K458 G482 4.2.1.2 E9AE57 31743022 NADFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uoi A 1.95 BS02 FE A 1 G216 N219 T468 R471 G191 N194 T435 R438 4.2.1.2 E9AE57 31743022 NADFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6up9 B 1.95 BS01 SF4 B 1 C133 Q134 D135 G214 S217 A251 C252 C346 S347 A348 K491 G515 C106 Q107 D108 G187 S190 A224 C225 C319 S320 A321 K455 G479 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPATAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6upm A 2.03 BS02 LMR A 1 Q134 D135 R173 G216 R421 T468 R471 K491 Q107 D108 R146 G189 R385 T432 R435 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPATAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6upm B 2.03 BS02 LMR B 1 Q134 D135 R173 G216 R421 A467 T468 R471 K491 Q107 D108 R146 G189 R385 A431 T432 R435 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPATAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6upo A 3.11 BS01 SF4 A 1 C133 D135 G214 G216 A251 C252 C346 A348 C106 D108 G187 G189 A224 C225 C319 A321 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRAGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uq8 A 1.34 BS02 LMR A 1 Q134 D135 R173 G215 G216 T467 T468 R471 K491 Q107 D108 R146 G188 G189 T431 T432 R435 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVAADIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uq9 A 2.30 BS01 LMR A 1 Q134 D135 R173 G216 T467 T468 R471 K491 Q107 D108 R146 G189 T432 T433 R436 K456 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVAADIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqb A 1.95 BS02 LMR A 1 Q134 D135 R173 G216 R421 T467 T468 K491 Q107 D108 R146 G189 R388 T434 T435 K458 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDITTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGAMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqb B 1.95 BS03 LMR B 1 Q134 D135 R173 G215 G216 R421 T467 T468 K491 Q107 D108 R146 G188 G189 R385 T431 T432 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGAMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqm A 2.00 BS02 LMR A 1 Q134 D135 G216 T467 T468 R471 K491 Q107 D108 G189 T433 T434 R437 K457 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLAYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDITSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqm B 2.00 BS02 LMR B 1 Q134 D135 G216 R421 T467 T468 R471 K491 Q107 D108 G189 R384 T430 T431 R434 K454 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLAYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqn A 3.30 BS01 SF4 A 1 C133 D135 G214 G216 S217 A251 C252 C346 A348 R350 K491 C108 D110 G189 G191 S192 A226 C227 C321 A323 R325 K457 4.2.1.2 E9AE57 31743022 NADFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLAYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqn B 3.30 BS01 SF4 B 1 C133 Q134 D135 G214 G216 A251 C252 C346 A348 R350 P466 K491 C106 Q107 D108 G187 G189 A224 C225 C319 A321 R323 P430 K455 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLAYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6uqn B 3.30 BS02 FUM B 1 Q134 D135 G215 G216 R421 T467 T468 R471 K491 M538 Q107 D108 G188 G189 R385 T431 T432 R435 K455 M502 4.2.1.2 E9AE57 31743022 DFHFSAIFQPTDPHHHQTEFAKVEGSEKYVEEVEVFGRQALKVNPEALTILAHRAFSDVHHFFRKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCWTGGEDEKYLSKGIWNAYRYHNLAYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLFIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTMKTVKLASCRYYDSLPTTGDKYGRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVIRLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPTSVKVDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGFYLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSKTLA 6v01 B 3.90 BS01 CA B 1 T27 T63 T22 T58 P0DP23 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 6v01 B 3.90 BS02 CA B 2 D59 G60 N61 G62 I64 D54 G55 N56 G57 I59 P0DP23 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 6v01 A 3.90 BS01 PT5 A 1 Y111 R116 R181 K183 K196 P197 L239 Q244 W248 Y8 R13 R78 K80 K93 P94 L130 Q135 W139 P51787 THVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPLREHHRATIKVIRRMQYFVAKKKFQQARKPYDIEQYSQGHLNLMVRIKELQRR