5qrf A 2.03 BS01 NUA A 1 S89 I125 H126 P127 S129 V175 R180 S49 I85 H86 P87 S89 V135 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrg A 1.95 BS01 JHP A 1 S89 L91 I125 S129 P130 V173 V175 S49 L51 I85 S89 P90 V133 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrh A 1.81 BS01 JMM A 1 S89 I125 S129 V175 S49 I85 S89 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qri A 1.83 BS01 NUY A 1 S89 I125 V175 R180 S49 I85 V135 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrj A 1.81 BS01 NWP A 1 V173 R174 V175 G176 R180 M181 I182 V133 R134 V135 G136 R140 M141 I142 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrk A 1.63 BS01 NWV A 1 S89 I125 H126 P127 S129 S49 I85 H86 P87 S89 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrl A 1.76 BS01 NWY A 1 S89 L91 I125 H126 P127 S129 S49 L51 I85 H86 P87 S89 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrm A 1.55 BS01 K1A A 1 Y198 Q199 E201 T204 Y158 Q159 E161 T164 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrn A 1.62 BS01 NX7 A 1 S89 L91 I125 V175 S49 L51 I85 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrp A 1.67 BS01 NXM A 1 S89 V175 R180 S49 V135 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrq A 2.10 BS01 NXS A 1 S89 I125 S129 P130 V175 R180 S49 I85 S89 P90 V135 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrr A 1.69 BS01 NY1 A 1 P120 S121 C122 V123 I125 P80 S81 C82 V83 I85 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrt A 1.77 BS01 GWA A 1 S89 V123 I125 S129 P130 V175 S49 V83 I85 S89 P90 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qru A 1.76 BS01 NY7 A 1 P117 Q118 A119 S121 M159 L160 N161 P77 Q78 A79 S81 M119 L120 N121 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrw A 1.74 BS01 NYV A 1 A119 P120 S121 C122 M159 N161 A79 P80 S81 C82 M119 N121 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrw A 1.74 BS02 NYV A 2 R101 L163 V195 T196 Q199 R61 L123 V155 T156 Q159 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrx A 1.87 BS01 NZG A 1 S89 L91 I125 S129 P130 V175 R180 S49 L51 I85 S89 P90 V135 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qrz A 1.96 BS01 NZ7 A 1 S89 I125 P130 V175 S49 I85 P90 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qs0 A 1.60 BS01 NZ4 A 1 H100 P111 G112 G113 P115 H60 P71 G72 G73 P75 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qs2 A 1.68 BS01 LV4 A 1 V123 R180 V83 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qs3 A 1.71 BS01 LJA A 1 S89 I125 S129 P130 V175 S49 I85 S89 P90 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qs4 A 1.65 BS01 JFP A 1 S89 I125 V175 S49 I85 V135 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qs5 A 1.81 BS01 NZJ A 1 S89 I125 S129 V175 R180 S49 I85 S89 V135 R140 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 5qsl A 2.20 BS01 O2A A 1 P117 Q118 A119 P120 S121 M159 L160 N161 P77 Q78 A79 P80 S81 M119 L120 N121 O15178 ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYN 6a6p A 2.10 BS01 9RF A 1 W228 V245 F246 R248 C249 T252 T253 H287 F291 L294 V305 V312 L317 I327 I328 H413 M417 L433 Y437 W58 V71 F72 R74 C75 T78 T79 H113 F117 L120 V131 V138 L143 I153 I154 H239 M243 L259 Y263 Q03181 QVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDM 6a6p A 2.10 BS02 B7G A 1 A414 M417 Q418 K421 L429 L433 Q434 Y437 K438 D439 M440 A240 M243 Q244 K247 L255 L259 Q260 Y263 K264 D265 M266 Q03181 QVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDM 6a6p B 2.10 BS02 B7G B 1 Q250 M417 Q418 K421 L429 H430 Q434 Y437 K438 M440 Q77 M244 Q245 K248 L256 H257 Q261 Y264 K265 M267 Q03181 QVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDM 6a8a A 1.80 BS01 ATP A 1 N209 T245 G247 A248 G250 K266 V268 A270 T273 G275 A276 G277 N302 A305 V309 N207 T243 G245 A246 G248 K264 V266 A268 T271 G273 A274 G275 N300 A303 V307 2.7.1.15 E9BIX7 RARNVRSHTGEYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFVLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHPSELPAGVM 6a8b A 2.01 BS01 ACP A 1 T245 G247 A248 G250 K266 V268 A270 T273 A276 G277 N302 A305 V309 T243 G245 A246 G248 K264 V266 A268 T271 A274 G275 N300 A303 V307 2.7.1.15 E9BIX7 RARNVRSHTGEYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFVLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHPSELPAGVM 6a8b B 2.01 BS01 ACP B 1 T245 G247 A248 G250 K266 V268 A270 T273 A276 G277 F280 N302 A305 T243 G245 A246 G248 K264 V266 A268 T271 A274 G275 F278 N300 A303 2.7.1.15 E9BIX7 RARNVRSHTGEYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFVLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHPSELPAGVM 6a8c A 1.98 BS01 ADP A 1 T245 G247 A248 G250 K266 T273 A276 G277 F280 N302 A305 V309 T243 G245 A246 G248 K264 T271 A274 G275 F278 N300 A303 V307 2.7.1.15 E9BIX7 RARNVRSHTGEYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFVLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQLSYPHPSELPAGVM 6a8d A 2.34 BS01 GDP A 1 D26 A27 A28 G29 K30 T31 T32 N126 K127 D129 M130 V159 A160 T161 D28 A29 A30 G31 K32 T33 T34 N128 K129 D131 M132 V161 A162 T163 A8ILA3 HHMGQAFTKLFDRWFGNREMRVVMLGLDAAGKTTILYKLHIGEVLTTVPTIGFNVEKVQYKNVVFTVWDVGGQEKLRPLWRHYFNNTDGLIFVVDSQDRDRIGKAAQEFQAILQDPLMLHSAILVFANKQDMKGCLTPAEVCTALGLSDMRTRKWHVQSSVATRGEGLYEGLDWLATTLKN 6a8o B 2.77 BS01 III P 1 H40 L41 C58 S97 Y143 T151 K192 G193 S195 W215 G216 H27 L28 C45 S88 Y134 T141 K185 G186 S188 W208 G209 3.4.21.34 P26262 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGGILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQ 6a8o B 2.77 BS02 MRZ P 1 D189 A190 T213 W215 G216 G219 G226 D182 A183 T206 W208 G209 G211 G219 3.4.21.34 P26262 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGGILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKTQ 6ak4 A 2.80 BS02 PD9 A 1 R96 Y106 Y108 L109 N205 V228 H231 D233 V244 Y295 H307 V309 R316 S318 T320 R322 R70 Y80 Y82 L83 N140 V163 H166 D168 V179 Y217 H229 V231 R238 S240 T242 R244 1.14.11.- Q9C0B1 30996080 RGSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGAEIAAACETFLKLNDYLQIETIQALEELAADIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA 6d3k B 2.60 BS01 ADP B 1 G279 V281 V294 K296 M366 E367 F368 C369 T373 S418 N419 F421 D432 G25 V27 V40 K42 M90 E91 F92 C93 T97 S142 N143 F145 D156 2.7.11.1,2.7.10.2 P19525 31246429 TKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKK 6d3k A 2.60 BS01 ADP A 1 S275 G279 V281 V294 K296 E367 C369 T373 S418 N419 F421 D432 S20 G24 V26 V39 K41 E91 C93 T97 S142 N143 F145 D156 2.7.11.1,2.7.10.2 P19525 31246429 KYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPE 6d3k C 2.60 BS01 ADP C 1 G276 G277 F278 G279 V281 V294 K296 M366 E367 C369 T373 S418 N419 F421 D432 G20 G21 F22 G23 V25 V38 K40 M86 E87 C89 T93 S138 N139 F141 D152 2.7.11.1,2.7.10.2 P19525 31246429 YTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKK 6ds1 A 2.12 BS01 NAP A 1 G14 K17 G18 I19 S38 R39 I61 D62 L63 N89 A90 G91 N112 I138 V139 S140 Y153 K157 P183 A184 E185 V186 L190 G14 K17 G18 I19 S38 R39 I61 D62 L63 N89 A90 G91 N112 I138 V139 S140 Y153 K157 P183 A184 E185 V186 L190 Q0PB28 MDLKIKNKVCIITGGAKGIGYGIAKLWASEGGIPVIFSRSMPKEHDKELKKLSSEYEFYEIDLKNYEQIEKLVKKVAIKHGGIYALVNNAGTNDNLHIENTSTQDLIKSYENNLFHYYTMTKECLPYIKKEQGSILNIVSKTGITGQGRTSAYASAKAAQMGFTREWACAFAKDNVRVNAIAPAEVMTPLYEKWLQNFPNPKEQYEKIAKAIPLGHRFTTIEEIANTAVFTLSPLASHTTGQILMPDGGYVHLDRALN 6ds1 A 2.12 BS02 MG A 1 I61 D62 N65 I61 D62 N65 Q0PB28 MDLKIKNKVCIITGGAKGIGYGIAKLWASEGGIPVIFSRSMPKEHDKELKKLSSEYEFYEIDLKNYEQIEKLVKKVAIKHGGIYALVNNAGTNDNLHIENTSTQDLIKSYENNLFHYYTMTKECLPYIKKEQGSILNIVSKTGITGQGRTSAYASAKAAQMGFTREWACAFAKDNVRVNAIAPAEVMTPLYEKWLQNFPNPKEQYEKIAKAIPLGHRFTTIEEIANTAVFTLSPLASHTTGQILMPDGGYVHLDRALN 6ds1 D 2.12 BS01 NAP D 1 G14 K17 G18 I19 S38 R39 S40 I61 D62 L63 N89 A90 G91 N112 Y117 I138 V139 S140 Y153 K157 P183 A184 E185 V186 L190 Y191 G14 K17 G18 I19 S38 R39 S40 I61 D62 L63 N89 A90 G91 N112 Y117 I138 V139 S140 Y153 K157 P183 A184 E185 V186 L190 Y191 Q0PB28 MDLKIKNKVCIITGGAKGIGYGIAKLWASEGGIPVIFSRSMPKEHDKELKKLSSEYEFYEIDLKNYEQIEKLVKKVAIKHGGIYALVNNAGTNDNLHIENTSTQDLIKSYENNLFHYYTMTKECLPYIKKEQGSILNIVSKTGITGQGRTSAYASAKAAQMGFTREWACAFAKDNVRVNAIAPAEVMTPLYEKWLQNFPNPKEQYEKIAKAIPLGHRFTTIEEIANTAVFTLSPLASHTTGQILMPDGGYVHLDRALNW 6dz4 B 1.45 BS03 PLS B 1 A85 H86 K87 T110 G111 A112 G113 Q114 H115 T190 C230 G232 G233 G234 S235 N236 G303 L304 D305 E350 S377 A84 H85 K86 T109 G110 A111 G112 Q113 H114 T189 C229 G231 G232 G233 S234 N235 G302 L303 D304 E349 S376 4.2.1.20 P0A2K1 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGE 6dzg A 1.87 BS01 ADP A 1 R149 N153 F163 S220 M222 R137 N141 F151 S208 M210 2.7.4.1 Q92SA6 GSRAVELEIDGRSRIFDIDDPDLPKWIDEEAFRSDDYPYKKKLDREEYEETLTKLQIELVKVQFWMQATGKRVMAVFEGRDAAGKGGAIHATTANMNPRSARVVALTKPTETERGQWYFQRYVATFPTAGEFVLFDRSWYNRAGVEPVMGFCTPDQYEQFLKEAPRFEEMIANEGIHLFKFWINIGREMQLKRFHDRRHDPLKIWKLSPMDIAALSKWDDYTGKRDRMLKETHTEHGPWAVIRGNDKRRSRINVIRHMLTKLDYDGKDEAAIGEVDEKILGSGPGFLR 6dzg B 1.87 BS01 ADP B 1 K120 R149 N153 V157 F163 S220 M222 K108 R137 N141 V145 F151 S208 M210 2.7.4.1 Q92SA6 GSRAVELEIDGRSRIFDIDDPDLPKWIDEEAFRSDDYPYKKKLDREEYEETLTKLQIELVKVQFWMQATGKRVMAVFEGRDAAGKGGAIHATTANMNPRSARVVALTKPTETERGQWYFQRYVATFPTAGEFVLFDRSWYNRAGVEPVMGFCTPDQYEQFLKEAPRFEEMIANEGIHLFKFWINIGREMQLKRFHDRRHDPLKIWKLSPMDIAALSKWDDYTGKRDRMLKETHTEHGPWAVIRGNDKRRSRINVIRHMLTKLDYDGKDEAAIGEVDEKILGSGPGFLR 6dzg D 1.87 BS01 AMP D 1 K120 R149 N153 F163 S220 M222 K108 R137 N141 F151 S208 M210 2.7.4.1 Q92SA6 GSRAVELEIDGRSRIFDIDDPDLPKWIDEEAFRSDDYPYKKKLDREEYEETLTKLQIELVKVQFWMQATGKRVMAVFEGRDAAGKGGAIHATTANMNPRSARVVALTKPTETERGQWYFQRYVATFPTAGEFVLFDRSWYNRAGVEPVMGFCTPDQYEQFLKEAPRFEEMIANEGIHLFKFWINIGREMQLKRFHDRRHDPLKIWKLSPMDIAALSKWDDYTGKRDRMLKETHTEHGPWAVIRGNDKRRSRINVIRHMLTKLDYDGKDEAAIGEVDEKILGSGPGFLR 6dzh A 1.95 BS01 GDP A 1 D13 V14 G15 K16 S17 A18 F28 V29 N116 K117 D119 L120 S145 A146 K147 D13 V14 G15 K16 S17 A18 F28 V29 N115 K116 D118 L119 S144 A145 K146 P01112 MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6dzh B 1.95 BS01 GDP B 1 D13 V14 G15 K16 S17 A18 F28 D30 E31 D33 N116 K117 D119 L120 S145 A146 K147 D13 V14 G15 K16 S17 A18 F28 D30 E31 D33 N104 K105 D107 L108 S133 A134 K135 P01112 MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6dzh B 1.95 BS02 MG B 1 G138 H166 G126 H154 P01112 MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6dzh B 1.95 BS04 CA B 1 D13 D33 D13 D33 P01112 MTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6dzh C 1.95 BS01 GDP C 1 D13 V14 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 D13 V14 G15 K16 S17 A18 F28 N103 K104 D106 L107 S132 A133 P01112 MTEYKLVVVGAGDVGKSALTIQLIQNHFVSYRKQVVIDGETCLLDILDTAGQEEYDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 6dzo B 1.64 BS02 CS B 2 V231 G232 E256 G268 P270 S308 V309 V230 G231 E255 G267 P269 S307 V308 4.2.1.20 P0A2K1 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGAHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARG 6dzx B 1.68 BS01 MED B 1 Y81 F98 Q99 H100 Y103 N153 R156 N213 N238 Y39 F56 Q57 H58 Y61 N111 R114 N171 N196 C6S9R8 KEIVFGTTVGDFGDMVKEQIQAELEKKGYTVKLVEFTDYVRPNLALAEGELDINVFQHKPYLDDFKKEHNLDITEVFQVPTAPLGLYPGKLKSLEEVKDGSTVSAPNDPSNFARVLVMLDELGWIKLKDGINPLTASKADIAENLKNIKIVELEAAQLPRSRADVDFAVVNGNYAISSGMKLTEALFQEPSFAYVNWSAVKTADKDSQWLKDVTEAYNSDAFKAYAHKRFEGYKSPAAWNE 6e0e A 2.70 BS02 HKM A 1 Y61 V62 R63 S64 P66 I159 I211 Y214 M235 V452 V455 Y48 V49 R50 S51 P53 I146 I198 Y201 M222 V439 V442 2.7.1.2 P35557 TLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKAC 6e0i A 1.90 BS02 HKG A 1 Y61 V62 R63 S64 I159 I211 Y214 M235 L451 V452 V455 Y61 V62 R63 S64 I149 I201 Y204 M225 L441 V442 V445 2.7.1.2 P35557 MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPSEVGDFLSLDLGGTNFRVMLVKVGVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACK 6e1a A 3.10 BS01 HL7 A 1 S178 E179 D180 H181 F238 C241 A242 Y276 M278 N282 Y319 M322 Y323 G326 W341 E363 V367 V371 S174 E175 D176 H177 F234 C237 A238 Y272 M274 N278 Y315 M318 Y319 G322 W337 E359 V363 V367 O00255 31244110 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6e1a A 3.10 BS02 7PR A 1 F365 N369 D370 F439 F361 N365 D366 F419 O00255 31244110 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6e1a A 3.10 BS03 7PR A 2 W126 L129 Y133 W122 L125 Y129 O00255 31244110 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6e1a A 3.10 BS04 7PR A 3 S246 D252 L286 S242 D248 L282 O00255 31244110 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTA 6e1x A 1.35 BS01 SP5 A 1 Y30 W31 F32 F85 Q86 I87 H122 Y134 E148 F149 Y29 W30 F31 F84 Q85 I86 H121 Y133 E147 F148 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNR 6e1x C 1.35 BS01 HLG C 1 Y30 W31 I74 F85 Q86 I87 H122 Y134 Y33 W34 I77 F88 Q89 I90 H125 Y137 2.3.1.57 Q9KL03 SNAMNSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 6e1x D 1.35 BS01 SP5 D 1 Y30 W31 I74 F85 Q86 I87 L121 H122 Y134 Y33 W34 I77 F88 Q89 I90 L124 H125 Y137 2.3.1.57 Q9KL03 SNAMNSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 6fm4 B 2.70 BS01 NUC E 1 E435 D437 S438 R458 G459 K460 D508 D512 R1033 H1046 H1079 H1081 G1082 S1085 R1092 I1175 R1272 E19 D21 S22 R42 G43 K44 D92 D96 R214 H227 H260 H262 G263 S266 R273 I356 R453 5.99.1.3 Q99XG5 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLG 6fm4 B 2.70 BS02 NUC F 1 K460 I461 L462 N463 K466 R471 N475 H515 M622 V626 R629 F1022 R1122 F1123 I1175 A1176 G1178 M1179 A1180 K44 I45 L46 N47 K50 R55 N59 H99 M172 V176 R179 F203 R303 F304 I356 A357 G359 M360 A361 5.99.1.3 Q99XG5 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLG 6fm4 D 2.70 BS01 NUC E 1 K460 I461 L462 N463 K466 R471 H515 M622 V626 R629 F1022 R1122 F1123 I1175 G1178 M1179 A1180 R1238 S1330 K44 I45 L46 N47 K50 R55 H99 M172 V176 R179 F202 R302 F303 I355 G358 M359 A360 R418 S510 5.99.1.3 Q99XG5 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 6fm4 D 2.70 BS02 NUC F 1 E435 D437 S438 R458 G459 K460 D508 D512 R1033 K1043 V1045 H1046 H1079 H1081 G1082 S1085 R1092 S1173 I1175 Q1267 R1272 E19 D21 S22 R42 G43 K44 D92 D96 R213 K223 V225 H226 H259 H261 G262 S265 R272 S353 I355 Q447 R452 5.99.1.3 Q99XG5 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 6fm4 D 2.70 BS03 DU5 E 1 M1075 D1083 M1121 M255 D263 M301 5.99.1.3 Q99XG5 KLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPTGYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYNERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL 6fxj A 1.79 BS01 FEC A 1 S111 Y113 L114 Y147 M149 K151 W159 I171 H174 G178 R179 Q187 I189 W200 L204 I215 M219 S225 S111 Y113 L114 Y147 M149 K151 W159 I171 H174 G178 R179 Q187 I189 W200 L204 I215 M219 S225 1.11.1.- Q8Y5F1 MNEAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYLASHMAGGDDPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj B 1.79 BS01 FEC B 1 L110 S111 R133 Y147 M149 K151 W159 I171 H174 G178 R179 Q187 W200 V202 L204 M219 S225 F231 L108 S109 R119 Y133 M135 K137 W145 I157 H160 G164 R165 Q173 W186 V188 L190 M205 S211 F217 1.11.1.- Q8Y5F1 EAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj B 1.79 BS02 POL B 1 Y102 S233 Y100 S219 1.11.1.- Q8Y5F1 EAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj B 1.79 BS03 POL B 2 D197 Y198 D183 Y184 1.11.1.- Q8Y5F1 EAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj C 1.79 BS01 FEC C 1 S111 R133 Y147 M149 K151 W159 H174 G178 R179 Q187 I189 W200 V202 I215 M219 S109 R119 Y133 M135 K137 W145 H160 G164 R165 Q173 I175 W186 V188 I201 M205 1.11.1.- Q8Y5F1 EAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj C 1.79 BS04 POL C 3 Q126 N127 Q112 N113 1.11.1.- Q8Y5F1 EAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj D 1.79 BS01 FEC D 1 S111 Y113 Y147 M149 K151 W159 I171 H174 G178 R179 Q187 W200 L204 I215 M219 S225 F231 S110 Y112 Y146 M148 K150 W158 I170 H173 G177 R178 Q186 W199 L203 I214 M218 S224 F230 1.11.1.- Q8Y5F1 NEAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYLASHMAGGDDPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj D 1.79 BS02 POL D 1 K67 T101 Y102 S233 F235 K66 T100 Y101 S232 F234 1.11.1.- Q8Y5F1 NEAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYLASHMAGGDDPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxj E 1.79 BS01 FEC E 1 S111 Y113 R133 Y147 M149 K151 W159 I171 H174 G178 R179 Q187 I189 W200 V202 L204 I215 M219 S225 F231 S108 Y110 R120 Y134 M136 K138 W146 I158 H161 G165 R166 Q174 I176 W187 V189 L191 I202 M206 S212 F218 1.11.1.- Q8Y5F1 AVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxq A 1.69 BS01 FEC A 1 S111 Y113 L114 R133 Y147 M149 K151 I171 H174 G175 G178 R179 Y181 V185 Q187 I189 W200 V202 L204 I215 V216 M219 S225 F231 S108 Y110 L111 R130 Y144 M146 K148 I168 H171 G172 G175 R176 Y178 V182 Q184 I186 W197 V199 L201 I212 V213 M216 S222 F228 1.11.1.- Q8Y5F1 AVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYLASHMAGGDDPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxq A 1.69 BS02 VOV A 1 L110 S111 Y113 R133 Y147 M149 K151 W159 I171 H174 G178 R179 V185 Q187 W200 V202 L204 I215 M219 S225 F231 L107 S108 Y110 R130 Y144 M146 K148 W156 I168 H171 G175 R176 V182 Q184 W197 V199 L201 I212 M216 S222 F228 1.11.1.- Q8Y5F1 AVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYLASHMAGGDDPYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxq B 1.69 BS01 FEC B 1 E109 S111 Y147 M149 K151 W159 I171 H174 G175 G178 R179 Q187 W200 V202 L204 I215 V216 M219 S225 F231 E104 S106 Y129 M131 K133 W141 I153 H156 G157 G160 R161 Q169 W182 V184 L186 I197 V198 M201 S207 F213 1.11.1.- Q8Y5F1 KTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6fxq C 1.69 BS02 VOV C 1 L110 S111 Y113 Y147 M149 W159 H174 G178 R179 V185 Q187 W200 V202 L204 I215 M219 S225 F231 L108 S109 Y111 Y133 M135 W145 H160 G164 R165 V171 Q173 W186 V188 L190 I201 M205 S211 F217 1.11.1.- Q8Y5F1 EAVKTLDGWFCLHDFRSIDWAAWRELNPGNQELMLNELSHFLSDMEITKNIGEGEHTIYSILGQKADLVFFTLRDSLEALNEVENRFNKLAIADYLLPTYSYISVVELSNYQNKGVRARLYPALPPKKHICFYPMSKKRDGADNWYMLPMEERQQLIRDHGLIGRSYAGKVQQIIGGSIGFDDYEWGVTLFSDDALEFKRIVTEMRFDEASARYAEFGSFFIGNLLLSEQLSKLFTI 6gvw B 3.75 BS01 ZN B 1 H122 H124 D135 H93 H95 D106 3.4.19.- P46737 31253574 AVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDIIRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSEYERIEIPIHIVPHITIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMEELSSLE 6gwy A 1.40 BS02 GOL A 2 A58 N113 T115 R146 S202 E203 V204 D205 A1 N56 T58 R89 S145 E146 V147 D148 F0X360 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 6gwy A 1.40 BS03 GOL A 3 N106 E107 R110 G144 N49 E50 R53 G87 F0X360 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 6gx0 A 1.25 BS01 GDU A 1 F121 I123 K124 Y126 W181 V184 S185 R188 D211 V212 D213 G267 A268 W300 H301 D302 E303 F64 I66 K67 Y69 W124 V127 S128 R131 D154 V155 D156 G210 A211 W243 H244 D245 E246 F0X360 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 6gx1 A 1.60 BS01 UD2 A 1 F121 A122 I123 K124 Y126 W181 V184 R188 D211 V212 D213 W300 F61 A62 I63 K64 Y66 W121 V124 R128 D151 V152 D153 W240 F0X360 EFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 6gx2 A 1.07 BS02 UDP A 1 F121 I123 K124 Y126 V184 S185 R188 D211 V212 D213 K346 H348 R352 F64 I66 K67 Y69 V127 S128 R131 D154 V155 D156 K289 H291 R295 F0X360 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP 6gxq A 1.96 BS02 FFZ A 1 M785 D822 I823 N825 A837 M861 G873 Q874 F877 M200 D237 I238 N240 A252 M276 G288 Q289 F292 3.1.4.- Q8WQX9 VTAITKVEREAVLVCELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR 6gxx L 1.85 BS01 MG L 1 A12 E105 Y140 Y173 A12 E109 Y144 Y177 DIVLTQSPDSLAVSLGQRATISCRASESVDNYGISFMNWFQQKPGQPPKLLIYAASNQGSGVPARFSGSGSGTDFSLNIHPMEEDDTAMYFCQQSKEVPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 6gy2 A 3.11 BS01 III D 1 K413 W414 V415 D416 Y417 Y485 E488 H489 L490 L491 R516 H538 K540 K44 W45 V46 D47 Y48 Y116 E119 H120 L121 L122 R147 H169 K171 2.7.11.21 P53350 VDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSS 6gye A 2.30 BS01 NNR A 1 R177 Y240 N243 S244 N248 L258 D291 E292 R293 R170 Y233 N236 S237 N241 L251 D284 E285 R286 A0A165F602 KSKLSGKNIGIYFGTFAPLHTGHQQQIYKCASLNDGVLLVVSGYDNDRGAQIGLPLEKRFRYLREAFNDEENIKVSMLNENDLPEMPNGWDEWANRLFELIHHNTLENDLSVTFYVGELEYAAELKKRFPADGNQYAVEIADRHDISLSATQIRENPQEHWTHINRVFRRHFSKVVTVMGSASTGKTTLVRRLARSINAPFSEEYAREYEEAFNIDDDELKMDDYARMITGQYDANSREVNSPANQGIVFLDTDAIVTRVYAKLYLPKEDFEQLEPLFRKTIADERMDLILVIPPITFRHMEWEESRHEFHEELMRQLAEFGLLDKVVILDDEGYLTRYHHAIDAVHEYTGVKIERLSY 6gye B 2.30 BS01 NNR B 1 R177 Y240 N243 S244 L258 D291 E292 R293 R170 Y233 N236 S237 L251 D284 E285 R286 A0A165F602 KSKLSGKNIGIYFGTFAPLHTGHQQQIYKCASLNDGVLLVVSGYDNDRGAQIGLPLEKRFRYLREAFNDEENIKVSMLNENDLPEMPNGWDEWANRLFELIHHNTLENDLSVTFYVGELEYAAELKKRFPADGNQYAVEIADRHDISLSATQIRENPQEHWTHINRVFRRHFSKVVTVMGSASTGKTTLVRRLARSINAPFSEEYAREYEEAFNIDDDELKMDDYARMITGQYDANSREVNSPANQGIVFLDTDAIVTRVYAKLYLPKEDFEQLEPLFRKTIADERMDLILVIPPITFRHMEWEESRHEFHEELMRQLAEFGLLDKVVILDDEGDHRDQEGYLTRYHHAIDAVHEYTGVKIERLS 6gyf A 2.70 BS01 NMN A 1 K65 Y69 R177 H178 Y240 N243 S244 N248 L258 R293 K57 Y61 R164 H165 Y227 N230 S231 N235 L245 R280 A0A165F602 SKLSGKNIGIYFGTFAPLHTGHQQQIYKCASLNDGVLLVVSGYDNDRGAQIGLPLEKRFRYLREAFNDEENIKVSMLNENDLGWDEWANRLFELIHHNTLENDLSVTFYVGELEYAAELKKRFPADGNQYAVEIADRHDISLSATQIRENPQEHWTHINRVFRRHFSKVVTVMGSASTGKTTLVRRLARSINAPFSEEYAREYEEAFNIDDDELKMDDYARMITGQYDANSREVNSPANQGIVFLDTDAIVTRVYAKLYLPKEDFEQLEPLFRKTIADERMDLILVIPPITEYIDDGFRHMEWEESRHEFHEELMRQLAEFGLLDKVVILDDEGDGYLTRYHHAIDAVHEYTGVKIERLSY 6gyf A 2.70 BS02 MG A 1 R266 K270 R329 E333 R253 K257 R316 E320 A0A165F602 SKLSGKNIGIYFGTFAPLHTGHQQQIYKCASLNDGVLLVVSGYDNDRGAQIGLPLEKRFRYLREAFNDEENIKVSMLNENDLGWDEWANRLFELIHHNTLENDLSVTFYVGELEYAAELKKRFPADGNQYAVEIADRHDISLSATQIRENPQEHWTHINRVFRRHFSKVVTVMGSASTGKTTLVRRLARSINAPFSEEYAREYEEAFNIDDDELKMDDYARMITGQYDANSREVNSPANQGIVFLDTDAIVTRVYAKLYLPKEDFEQLEPLFRKTIADERMDLILVIPPITEYIDDGFRHMEWEESRHEFHEELMRQLAEFGLLDKVVILDDEGDGYLTRYHHAIDAVHEYTGVKIERLSY 6gyf A 2.70 BS03 MG A 2 E72 R177 E64 R164 A0A165F602 SKLSGKNIGIYFGTFAPLHTGHQQQIYKCASLNDGVLLVVSGYDNDRGAQIGLPLEKRFRYLREAFNDEENIKVSMLNENDLGWDEWANRLFELIHHNTLENDLSVTFYVGELEYAAELKKRFPADGNQYAVEIADRHDISLSATQIRENPQEHWTHINRVFRRHFSKVVTVMGSASTGKTTLVRRLARSINAPFSEEYAREYEEAFNIDDDELKMDDYARMITGQYDANSREVNSPANQGIVFLDTDAIVTRVYAKLYLPKEDFEQLEPLFRKTIADERMDLILVIPPITEYIDDGFRHMEWEESRHEFHEELMRQLAEFGLLDKVVILDDEGDGYLTRYHHAIDAVHEYTGVKIERLSY 6gyf B 2.70 BS02 MG B 1 R266 K270 E333 R259 K263 E321 A0A165F602 KSKLSGKNIGIYFGTFAPLHTGHQQQIYKCASLNDGVLLVVSGYDNDRGAQIGLPLEKRFRYLREAFNDEENIKVSMLNENDLPEMPNGWDEWANRLFELIHHNTLENDLSVTFYVGELEYAAELKKRFPADGNQYAVEIADRHDISLSATQIRENPQEHWTHINRVFRRHFSKVVTVMGSASTGKTTLVRRLARSINAPFSEEYAREYEEAFNIDDDELKMDDYARMITGQYDANSREVNSPANQGIVFLDTDAIVTRVYAKLYLPKEDFEQLEPLFRKTIADERMDLILVIPPITEFRHMEWEESRHEFHEELMRQLAEFGLLDKVVILDDEGDHRDQEGYLTRYHHAIDAVHEYTGVKIERLS 6i6c A 1.72 BS02 H4H A 1 L104 S157 L158 C159 F164 Y170 G199 P200 M205 Q206 A209 L222 L225 L110 S163 L164 C165 F170 Y176 G205 P206 M211 Q212 A215 L228 L231 1.1.1.153 P35270 31244106 HENLYFQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAEGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 6i6c B 1.72 BS02 H4H B 1 S157 L158 C159 F164 W167 Y170 P200 M205 Q206 A209 M218 L222 L225 S154 L155 C156 F161 W164 Y167 P197 M202 Q203 A206 M215 L219 L222 1.1.1.153 P35270 31244106 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 6i6f A 1.94 BS02 H4E A 1 L104 S157 L158 C159 W167 Y170 M205 Q206 A209 L222 L225 L109 S162 L163 C164 W172 Y175 M210 Q211 A214 L227 L230 1.1.1.153 P35270 31244106 HENLYFQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 6i6f B 1.94 BS01 NAP B 1 G14 S16 R17 G18 F19 A41 R42 N43 A68 D69 L70 N100 A101 G102 L126 I155 S156 S157 Y170 K174 P198 G199 L201 T203 M205 Q206 G11 S13 R14 G15 F16 A38 R39 N40 A64 D65 L66 N96 A97 G98 L122 I151 S152 S153 Y166 K170 P194 G195 L197 T199 M201 Q202 1.1.1.153 P35270 31244106 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAESGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 6i6p A 1.62 BS02 H4T A 1 S157 C159 F164 W167 Y170 P200 M205 Q206 A209 M218 L222 S166 C168 F173 W176 Y179 P209 M214 Q215 A218 M227 L231 1.1.1.153 P35270 31244106 HHENLYFQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK 6i6t A 1.79 BS02 H5B A 1 S157 L158 C159 W167 P200 L222 L225 Y259 S155 L156 C157 W165 P198 L220 L223 Y257 1.1.1.153 P35270 31244106 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK 6i6t A 1.79 BS03 H5B A 2 V9 V38 L83 R84 L86 P87 R88 F142 V7 V36 L81 R82 L84 P85 R86 F140 1.1.1.153 P35270 31244106 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK 6i6t B 1.79 BS02 H5B B 1 S157 L158 W167 P200 M218 L222 L225 Y259 S155 L156 W165 P198 M216 L220 L223 Y257 1.1.1.153 P35270 31244106 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK 6i6t B 1.79 BS03 H5B B 2 V9 V36 V38 L83 R84 L86 P87 R88 A141 F142 V7 V34 V36 L81 R82 L84 P85 R86 A139 F140 1.1.1.153 P35270 31244106 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK 6i6v A 1.43 BS02 H6E A 1 L104 S157 F164 W167 Y170 P200 M205 Q206 M218 L222 L110 S163 F170 W173 Y176 P206 M211 Q212 M224 L228 1.1.1.153 P35270 31244106 HENLYFQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAEGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 6i6v B 1.43 BS02 H6E B 1 L104 L158 F164 W167 Y170 P200 M205 Q206 L101 L155 F161 W164 Y167 P197 M202 Q203 1.1.1.153 P35270 31244106 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYD 6i79 A 1.63 BS02 H5E A 1 L104 S157 C159 F164 W167 Y170 P200 M205 Q206 L222 L225 L114 S167 C169 F174 W177 Y180 P210 M215 Q216 L232 L235 1.1.1.153 P35270 31244106 HHHENLYFQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK 6ig2 D 2.88 BS01 CTP D 1 Y78 Y144 K156 R180 K183 D234 M237 S238 A241 R245 I250 Q254 Y46 Y105 K117 R141 K144 D195 M198 S199 A202 R206 I211 Q215 2.7.7.41 O74339 31178220 CTVAQLLKQNLLTFENQRIQPEEELKENLTKVVNYFQAPIDVAVGYGSGVFRQNPMIDFIFQVEDPVKWHKINLQQNPSHYSFVKNFGPGFVSTLQESFGTGVYYNTHVEVEGNIIKYGVTSKKDVYEDLKNWNTMYLAGRFQKPVVILKGEDEFYKENSYNLSSALHVGLLMLADRFTEFDLYKTIVSLSYLGDIRMSFAAENPRKVENIVSKQIAFFRKLYLPLLYAEPGVHFIESSEVLKSMDPSDNSRYLSFHQNITKDSISRLLNGLPLNLVK 6ig4 A 2.26 BS01 3G0 A 1 G79 S80 R180 R245 K253 Q254 G47 S48 R141 R206 K214 Q215 2.7.7.41 O74339 31178220 CTVAQLLKQNLLTFENQRIQPEEELKENLTKVVNYFQAPIDVAVGYGSGVFRQNPMIDFIFQVEDPVKWHKINLQQNPSHYSFVKNFGPGFVSTLQESFGTGVYYNTHVEVEGNIIKYGVTSKKDVYEDLKNWNTMYLAGRFQKPVVILKGEDEFYKENSYNLSSALHVGLLMLADRFTEFDLYKTIVSLSYLGDIRMSFFAENPRKVENIVSKQIAFFRKLYLPLLYAEPGVHFIESSEVLKSMDPSDNSRYLSFHQNITKDSISRLLNGLPLNLV 6ig4 B 2.26 BS01 3G0 B 1 G79 S80 R180 F240 R245 I250 K253 Q254 G47 S48 R136 F196 R201 I206 K209 Q210 2.7.7.41 O74339 31178220 CTVAQLLKQNLLTFENQRIQPEEELKENLTKVVNYFQAPIDVAVGYGSGVFRQNPMIDFIFQVEDPVKWHKINLQQNPSHYSFVKNVSTLQESFGTGVYYNTHVEVEGNIIKYGVTSKKDVYEDLKNWNTMYLAGRFQKPVVILKGEDEFYKENSYNLSSALHVGLLMLADRFTEFDLYKTIVSLSYLGDIRMSFFAENPRKVENIVSKQIAFFRKLYLPLLYAEPGVHFIESSEVLKSMDPSDNSRYLSFHQNITKDSISRLLNGLPLNLV 6j66 A 1.95 BS01 CA A 1 D56 H263 D343 H344 D11 H217 D297 H298 3.1.6.12 A0A0C5AQI9 31244815 KKPNLLIVFPDEMRAHTLGFMNQDRSYTPNLNKFAKESAVLKQAVSNFPLTPFRGMLMTGQYPYRNGIQGNSHTAMPGNFGGKDFGIELKKSTRTWSDILKDQGYSMGYIGKWHLDTPEAPFIPSYNNPMEGRYWNDWTAPDRRHGFDFWYAYGTYDKHLTPIYWTNETPRDQPIKVNQWSPEHEADIAIKYLRNENGHYRDRDKPFTLVVSMNPPHSPYDQVPQKYLDKFDGETSRSLNTRPNVQWDQEYLEGYGPEYFKEYMAMVHGVDDQFGRIIDELDRLGLTEDTLVVFFSDHGCCMGSNGKPTKNVHYEEAMRIPMMFRWPGKLTPRQDDLLFSAPDIYPTLFGLMGLEELIPDTVEGTNFAKTVSGIEGDTRPTSQLYTFMPYGGQSYGRRGVRTDRYTLMIDRKIAKPLTFVLHDNQNDPYQMTNIANDNQELIAQLIEKELIPWLELTGDPWRPTEVPASVAKAY 6jf1 A 1.95 BS01 MET A 1 Y73 F90 Q91 H92 F95 Y114 N151 R154 N210 N211 T212 N239 Y50 F67 Q68 H69 F72 Y91 N128 R131 N187 N188 T189 N215 A0A0H2UN92 MRGSHHHHHHTTIKIATVNRSGSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYKKSLFKEQADNSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQPVW 6jf1 A 1.95 BS02 ZN A 1 H-17 H-15 H5 H7 A0A0H2UN92 MRGSHHHHHHTTIKIATVNRSGSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYKKSLFKEQADNSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQPVW 6jf1 A 1.95 BS03 ZN A 2 E48 E69 E25 E46 A0A0H2UN92 MRGSHHHHHHTTIKIATVNRSGSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYKKSLFKEQADNSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQPVW 6jf1 A 1.95 BS04 ZN A 3 N147 E152 E191 N124 E129 E168 A0A0H2UN92 MRGSHHHHHHTTIKIATVNRSGSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYKKSLFKEQADNSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQPVW 6jf1 A 1.95 BS06 ZN A 5 H-14 H-12 D52 H8 H10 D29 A0A0H2UN92 MRGSHHHHHHTTIKIATVNRSGSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYKKSLFKEQADNSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQPVW 6jf1 A 1.95 BS08 ZN A 7 D220 K222 D197 K199 A0A0H2UN92 MRGSHHHHHHTTIKIATVNRSGSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKENGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAKLDYKKSLFKEQADNSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESSDGLDQPVW 6jl9 A 2.00 BS01 CA A 1 D121 P122 D92 P93 F6VRB7 HHHHHHPVTPCEAPLQWEGRIVLYDHNTGKNTRATVTYDAILQRIRILEEKKSFVPCKRFFEYIFLYQEAVMFQIEQVTKICSKNTLTEPWDPYDIPENSTYEDQYYIGGPGDQIPVQEWSDRKPARKYETWVGVYTVKDCYPVQETYTKNDSMTTSTRFFDIKLGISDPSVFNPPSTCEAAQPLLMSG 6k1h Z 3.52 BS01 MAN Z 1 W35 Q41 N76 T77 Q78 P79 D123 W127 W19 Q25 N60 T61 Q62 P63 D107 W111 P69805 TQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACG 6k1h Y 3.52 BS01 MAN Z 1 N65 G67 N62 G64 TTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLGDMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPLAAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVALSVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAAFTNFNLVALGVIGTVMAVLYIQLSPKYNRV 6k1h C 3.52 BS01 MAN C 1 W35 Q41 N76 Q78 D123 W127 W19 Q25 N60 Q62 D107 W111 P69805 TQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLATRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGYACG 6k28 A 2.00 BS01 TZE A 1 P47 M49 P39 M41 2.7.1.50 W9BB97 PVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGMTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALYQE 6k28 A 2.00 BS02 TZE A 2 N29 V32 G71 T72 V196 C200 N21 V24 G63 T64 V177 C181 2.7.1.50 W9BB97 PVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGMTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALYQE 6k28 A 2.00 BS03 MG A 1 D98 V100 R124 G125 E129 D90 V92 R116 G117 E121 2.7.1.50 W9BB97 PVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGMTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALYQE 6k28 B 2.00 BS01 TZE A 1 N29 V32 G71 T72 V100 V196 C200 N21 V24 G63 T64 V92 V176 C180 2.7.1.50 W9BB97 PVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALY 6k28 B 2.00 BS02 MG B 1 D98 V100 R124 E129 D90 V92 R116 E121 2.7.1.50 W9BB97 PVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALY 6k28 B 2.00 BS03 TZE C 1 P47 A48 M49 P39 A40 M41 2.7.1.50 W9BB97 PVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGTAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALY 6k28 C 2.00 BS02 TZE C 1 N29 G71 V196 G197 C200 N23 G65 V181 G182 C185 2.7.1.50 W9BB97 PAPVAHLRHLLRAHSPLVHCMTNDVVQTFTANVLLAVGASPAMVIDPREAAQFAAIADALLINVGTLTEDRAVAMRAAVEHARQAGKPWTLDPVAVGALTVRTAFCHELLALQPAAIRGNASEILALAGMSATAAAALPAAQALARRLATVVAVTGEVDYVTDGERVLSVAGGNPLMTRVVGTGCALSAVVAASAALPGDRLENVAAACGLMKQAGEIAARQGGPGSFIPAFLDALYQE 6k2k A BS01 ZN A 1 C302 C305 S308 C323 C326 C7 C10 S13 C28 C31 2.3.2.27 Q969V5 31235254 GSLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS 6k2k A BS02 ZN A 2 E316 C317 H319 C336 C339 E21 C22 H24 C41 C44 2.3.2.27 Q969V5 31235254 GSLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS 6k72 P 4.60 BS01 III M 1 I192 K201 P223 Y230 N231 I153 K162 P184 Y191 N192 P41091 31048492 ATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIR 6kbs B 1.60 BS01 NUC D 1 G3 R4 P40 W67 W68 K70 L73 N75 R77 S84 R85 M86 F87 W106 K113 T149 H160 R162 G209 N210 V211 G2 R3 P39 W66 W67 K69 L72 N74 R76 S83 R84 M85 F86 W105 K112 T148 H159 R161 G208 N209 V210 3.4.-.- A0A2S5ZH06 CGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKVLLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADGWFEWKKEGDKKQPFFIYRADGQPIFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIHDRRPLVLSPEAAREWMRQEISGKEASEIAASGCVPANQFSWHPVSRAVGNVKNQGAELIQPVLEVLFQ 6kbx B 1.22 BS01 NUC A 1 C2 G3 W67 W68 K70 L73 N75 R77 S84 R85 M86 F87 T149 H160 R162 C1 G2 W66 W67 K69 L72 N74 R76 S83 R84 M85 F86 T148 H159 R161 3.4.-.- A0A2S5ZH06 CGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKVLLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADGWFEWKKEGDKKQPFFIYRADGQPIFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIHDRRPLVLSPEAAREWMRQEISGKEASEIAASGCVPANQFSWHPVSRAVGNVKNQGAELIQPVLEVLF 6kbz B 1.65 BS01 NUC A 1 C2 G3 R4 P40 W67 W68 L73 I74 N75 R77 S84 R85 M86 F87 W106 K113 T149 R162 G209 N210 V211 C1 G2 R3 P39 W66 W67 L72 I73 N74 R76 S83 R84 M85 F86 W105 K112 T148 R161 G208 N209 V210 3.4.-.- A0A2S5ZH06 CGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKVLLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADGWFEWKKEGDKKQPFFIYRADGQPIFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIHDRRPLVLSPEAAREWMRQEISGKEASEIAASGCVPANQFSWHPVSRAVGNVKNQGAELIQPVLEVLF 6kcq B 1.70 BS01 NUC A 1 C2 G3 R4 P40 W67 W68 L73 N75 R77 S84 R85 M86 F87 E105 W106 K113 T149 H160 R162 G209 C1 G2 R3 P39 W66 W67 L72 N74 R76 S83 R84 M85 F86 E104 W105 K112 T148 H159 R161 G208 3.4.-.- A0A2S5ZH06 CGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKVLLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADGWFEWKKEGDKKQPFFIYRADGQPIFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIHDRRPLVLSPEAAREWMRQEISGKEASEIAASGCVPANQFSWHPVSRAVGNVKNQGAELIQPV 6mcw A 2.40 BS01 JDJ A 1 Y79 F92 E178 M179 I181 Q182 F256 A257 H260 V434 Y76 F89 E175 M176 I178 Q179 F253 A254 H257 V431 1.14.13.70 Q603T8 PPSNTPPVKPGGLPLLGHILEFGKNPHAFLMALRHEFGDVAEFRMFHQRMVLLTGSQASEAFYRAPDEVLDQGPAYRIMTPIFGRGVVFDARIERKNQQLQMLMPALRDKPMRTYSEIIVAEVEAMLRDWKDAGTIDLLELTKELTIYTSSHCLLGAEFRHELNTEFAGIYRDLEMGIQPIAYVFPNLPLPVFKRRDQARVRLQELVTQIMERRARSQERSTNVFQMLIDASYDDGSKLTPHEITGMLIATIFAGHHTSSGTTAWVLIELLRRPEYLRRVRAEIDALFETHGRVTFESLRQMPQLENVIKEVLRLHPPLILLMRKVMKDFEVQGMRIEAGKFVCAAPSVTHRIPELFPNPELFDPDRYTPERAEDKDLYGWQAFGGGRHKCSGNAFAMFQIKAIVCVLLRNYEFELAAAPESYRDDYRKMVVEPASPCLIRYRRRD 6mcw A 2.40 BS02 HEM A 1 L103 A257 G258 T261 S262 P321 L322 R327 A386 F387 G388 H392 K393 C394 S395 G396 F399 A400 L100 A254 G255 T258 S259 P318 L319 R324 A383 F384 G385 H389 K390 C391 S392 G393 F396 A397 1.14.13.70 Q603T8 PPSNTPPVKPGGLPLLGHILEFGKNPHAFLMALRHEFGDVAEFRMFHQRMVLLTGSQASEAFYRAPDEVLDQGPAYRIMTPIFGRGVVFDARIERKNQQLQMLMPALRDKPMRTYSEIIVAEVEAMLRDWKDAGTIDLLELTKELTIYTSSHCLLGAEFRHELNTEFAGIYRDLEMGIQPIAYVFPNLPLPVFKRRDQARVRLQELVTQIMERRARSQERSTNVFQMLIDASYDDGSKLTPHEITGMLIATIFAGHHTSSGTTAWVLIELLRRPEYLRRVRAEIDALFETHGRVTFESLRQMPQLENVIKEVLRLHPPLILLMRKVMKDFEVQGMRIEAGKFVCAAPSVTHRIPELFPNPELFDPDRYTPERAEDKDLYGWQAFGGGRHKCSGNAFAMFQIKAIVCVLLRNYEFELAAAPESYRDDYRKMVVEPASPCLIRYRRRD 6mi0 A 2.73 BS01 HEM A 1 Q75 L103 A257 G258 T261 S262 P321 L322 R327 A386 F387 G388 H392 K393 C394 F399 A400 Q72 L100 A254 G255 T258 S259 P318 L319 R324 A383 F384 G385 H389 K390 C391 F396 A397 1.14.13.70 Q603T8 PPSNTPPVKPGGLPLLGHILEFGKNPHAFLMALRHEFGDVAEFRMFHQRMVLLTGSQASEAFYRAPDEVLDQGPAYRIMTPIFGRGVVFDARIERKNQQLQMLMPALRDKPMRTYSEIIVAEVEAMLRDWKDAGTIDLLELTKELTIYTSSHCLLGAEFRHELNTEFAGIYRDLEMGIQPIAYVFPNLPLPVFKRRDQARVRLQELVTQIMERRARSQERSTNVFQMLIDASYDDGSKLTPHEITGMLIATIFAGHHTSSGTTAWVLIELLRRPEYLRRVRAEIDALFETHGRVTFESLRQMPQLENVIKEVLRLHPPLILLMRKVMKDFEVQGMRIEAGKFVCAAPSVTHRIPELFPNPELFDPDRYTPERAEDKDLYGWQAFGGGRHKCSGNAFAMFQIKAIVCVLLRNYEFELAAAPESYRDDYRKMVVEPASPCLIRYRRRD 6n0j A 1.79 BS02 K8S A 1 E18 V24 R26 L41 D43 F45 F53 S65 L67 M73 L114 Q115 W117 Q252 G254 E16 V22 R24 L39 D41 F43 F51 S63 L65 M71 L112 Q113 W115 Q250 G252 1.13.11.24 O00625 SSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRGFETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNLRSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVLIAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN 6n2i A 3.50 BS01 ADP A 1 D323 H324 P358 G359 V360 G361 K362 T363 S364 Y493 I501 H505 L506 K509 V541 R542 E545 D77 H78 P112 G113 V114 G115 K116 T117 S118 Y247 I255 H259 L260 K263 V295 R296 E299 3.4.21.53 A0A376KCZ4 31237118 APDENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRILEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLPKQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLKHIEINGDNLHDYLGVQRF 6njy A 1.76 BS01 BGC A 1 T108 K185 Y187 T116 K193 Y195 F3ZXK6 31232162 NLYFQSNAMTGYPYPRPQAVKIQVKGHVPYPKNALATVYDIFRDIETVNKAHEAKEAPPFAIKDFNMNGFAITSYLALPTDTVTERLKTKGFHTVGQPIYLPQNELPPLYGLKGVTIQFRTPTAFKYNTGYVPEFYGPVFIKSITESYRRIIPGCPEFSTSDILKYIRFTATDLQKGKYRLTEELMVTGFKGKVYLQFKLSTPPELKLLILYFLEAASICGVGMKKAWGMGDIYITI 6njy A 1.76 BS02 BGC A 2 P23 F57 K170 Y171 R172 P31 F65 K178 Y179 R180 F3ZXK6 31232162 NLYFQSNAMTGYPYPRPQAVKIQVKGHVPYPKNALATVYDIFRDIETVNKAHEAKEAPPFAIKDFNMNGFAITSYLALPTDTVTERLKTKGFHTVGQPIYLPQNELPPLYGLKGVTIQFRTPTAFKYNTGYVPEFYGPVFIKSITESYRRIIPGCPEFSTSDILKYIRFTATDLQKGKYRLTEELMVTGFKGKVYLQFKLSTPPELKLLILYFLEAASICGVGMKKAWGMGDIYITI 6njy B 1.76 BS01 BGC B 1 T162 Y187 T170 Y195 F3ZXK6 31232162 NLYFQSNAMTGYPYPRPQAVKIQVKGHVPYPKNALATVYDIFRDIETVNKAHEAKEAPPFAIKDFNMNGFAITSYLALPTDTVTERLKTKGFHTVGQPIYLPQNELPPLYGLKGVTIQFRTPTAFKYNTGYVPEFYGPVFIKSITESYRRIIPGCPEFSTSDILKYIRFTATDLQKGKYRLTEELMVTGFKGKVYLQFKLSTPPELKLLILYFLEAASICGVGMKKAWGMGDIYITI 6nng A 2.40 BS01 GTP A 1 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G142 G143 G144 T145 G146 I171 V177 S178 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G142 G143 G144 T145 G146 I171 V177 S178 E183 N206 Y224 N228 I231 Q2XVP4 31043459 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6nng B 2.40 BS02 DJ9 B 1 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 I316 N347 N348 K350 A352 I368 V235 C238 L239 L245 A247 D248 K251 L252 N255 M256 I315 N346 N347 K349 A351 I367 A0A287AGU7 31043459 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6nng D 2.40 BS01 GTP D 1 G10 Q11 C12 Q15 A97 G98 N99 S138 G141 G142 T143 G144 V175 S176 E181 N204 L207 Y222 N226 G10 Q11 C12 Q15 A97 G98 N99 S138 G141 G142 T143 G144 V175 S176 E181 N204 L207 Y222 N226 A0A287AGU7 31043459 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6nng F 2.40 BS02 ACP F 1 K74 I148 Q183 K184 Y185 L186 K198 D200 R202 R222 H239 T241 N242 D318 M320 I330 E331 N333 K74 I123 Q151 K152 Y153 L154 K166 D168 R170 R190 H207 T209 N210 D282 M284 I294 E295 N297 E1BQ43 31043459 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPREVFLAAYNRRREGREGNVWIAKSGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHHHHHH 6nt2 A 2.48 BS01 SAH A 1 Y57 H63 M66 R72 G96 S97 I101 L102 E118 C119 G144 K145 V146 E147 M173 T176 Y16 H22 M25 R31 G55 S56 I60 L61 E77 C78 G103 K104 V105 E106 M132 T135 2.1.1.319 Q99873 PNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 6nt2 A 2.48 BS02 KZS A 1 Y57 I62 E65 M66 E162 W163 M164 Y166 E171 M173 H311 Y16 I21 E24 M25 E121 W122 M123 Y125 E130 M132 H270 2.1.1.319 Q99873 PNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 6nt2 A 2.48 BS03 KZS D 1 S49 Y53 S8 Y12 2.1.1.319 Q99873 PNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 6nt2 D 2.48 BS02 KZS D 1 S56 Y57 I62 E65 M66 E162 W163 M164 Y166 Y170 E171 M173 H311 W312 S15 Y16 I21 E24 M25 E121 W122 M123 Y125 Y129 E130 M132 H270 W271 2.1.1.319 Q99873 PNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 6nvg A 1.99 BS01 XL8 A 1 L473 V481 R483 A501 K503 E520 M524 I534 V548 V550 E551 C552 A553 G556 L610 A620 D621 F622 L21 V29 R31 A49 K51 E68 M72 I82 V96 V98 E99 C100 A101 G104 L158 A168 D169 F170 2.7.10.1 P22455 DLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVS 6nvi A 2.12 BS01 XL7 A 1 L473 V481 R483 T499 A501 K503 E520 M524 I534 V550 E551 C552 A553 G556 L610 A620 D621 F622 L21 V25 R27 T43 A45 K47 E64 M68 I78 V94 E95 C96 A97 G100 L152 A162 D163 F164 2.7.10.1 P22455 DLPLDPLWEFPRDRLVLGKPLGEQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 6nvk A 2.30 BS01 XL9 A 1 L473 V481 R483 K503 E520 M524 I534 V548 V550 E551 C552 A553 A554 G556 L610 A620 D621 L21 V26 R28 K48 E65 M69 I79 V93 V95 E96 C97 A98 A99 G101 L155 A165 D166 2.7.10.1 P22455 DLPLDPLWEFPRDRLVLGKPLGEGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 6nvl A 2.70 BS01 XL6 A 1 L484 G487 C488 V492 A512 K514 E531 M535 I545 V561 E562 Y563 A564 S565 G567 N568 L630 A640 D641 F642 L22 G25 C26 V30 A50 K52 E69 M73 I83 V99 E100 Y101 A102 S103 G105 N106 L154 A164 D165 F166 2.7.10.1 P11362 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLYYKKTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 6nvl B 2.70 BS01 XL6 B 1 V492 A512 V513 K514 E531 M535 I545 V561 E562 Y563 A564 S565 G567 N568 L630 A640 D641 F642 V25 A43 V44 K45 E62 M66 I76 V92 E93 Y94 A95 S96 G98 N99 L150 A160 D161 F162 2.7.10.1 P11362 SEYELPEDPRWELPRDRLVLGKPQVVLAEAIGLDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT 6nvl D 2.70 BS01 XL6 D 1 A512 K514 E531 M535 I545 V561 E562 Y563 A564 S565 L630 A640 D641 F642 A32 K34 E49 M53 I63 V77 E78 Y79 A80 S81 L146 A156 D157 F158 2.7.10.1 P11362 WELPRDRLVLGKQVVLAEAIGLDKPNRVTKVAVKMLKSTEKDLSDLISEMEMMKMIGKHKNIINLLGACTGPLYVIVEYASKGNLREYLQARRPPGLEYSYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS 6nws A 2.44 BS01 L77 A 1 W317 C320 H323 L324 V361 M365 V376 F377 F378 F388 L396 I397 I400 F401 H479 L483 W53 C56 H59 L60 V97 M101 V112 F113 F114 F124 L132 I133 I136 F137 H215 L219 P51449 31172947 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSGGGEKHKILHRLLQDS 6nwt A 2.35 BS01 L7P A 1 Q286 W317 C320 H323 R364 M365 R367 A368 V376 F377 F378 L391 C393 L396 I400 H479 R482 L483 F486 Q22 W53 C56 H59 R100 M101 R103 A104 V112 F113 F114 L127 C129 L132 I136 H215 R218 L219 F222 P51449 31172947 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAA 6nwt C 2.35 BS01 L7P C 1 Q286 W317 C320 H323 L324 R364 M365 R367 A368 V376 F377 F378 L391 C393 L396 I400 H479 R482 Q22 W53 C56 H59 L60 R100 M101 R103 A104 V112 F113 F114 L127 C129 L132 I136 H215 R218 P51449 31172947 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQQAAFPPLYKELFSGN 6nwu A 3.20 BS01 L7J A 1 W317 C320 A321 H323 L324 V361 M365 V376 F378 F388 L391 C393 L396 I397 I400 H479 Y502 W53 C56 A57 H59 L60 V97 M101 V112 F114 F124 L127 C129 L132 I133 I136 H215 Y238 P51449 31172947 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSGGGEKHKILHRLLQDS 6nzt A 1.40 BS01 L9P A 1 Q1041 T1042 F1043 Y1056 H1057 G1058 D1081 I1132 L1135 K1136 G1137 S1138 S1139 F1154 R1155 A1156 A1157 Q53 T54 F55 Y68 H69 G70 D93 I144 L147 K148 G149 S150 S151 F166 R167 A168 A169 S4UY05 31133531 KGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVSTRGVAKAVQFIPVESLETTM 6nzv A 1.55 BS01 L9J A 1 Q1041 T1042 F1043 Y1056 H1057 G1058 V1078 D1081 R1123 I1132 L1135 K1136 G1137 S1138 S1139 F1154 R1155 A1156 A1157 Q53 T54 F55 Y68 H69 G70 V90 D93 R135 I144 L147 K148 G149 S150 S151 F166 R167 A168 A169 S4UY05 31133531 KGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVSTRGVAKAVQFIPVESLETTM 6o0e A 2.50 BS01 9SL A 1 E540 Y558 F561 T563 P727 F784 D785 R786 Q787 K789 D794 Y795 E531 Y549 F552 T554 P694 F751 D752 R753 Q754 K756 D761 Y762 P31226 31223657 AKQVRWCAISDLEQKKCNDLVGSCNVPDITLVCVLRSSTEDCMTAIKDGQADAMFLDSGEVYEASKDPYNLKPIIAEPYSSNRDLQKCLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKISGTNTPPGQTRATCERHELPKCLKERQVALGGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGEEIAGTKTPPGKIPATCQKHDLVTTCHYAVAMVKKSSAFQFNQLKGKRSCHSGVSKTDGWKALVTVLVEKKLLSWDGPAKESIQRAMSKFFSVSCIPGATQTNLCKQCKGEEGKNCKNSHDEPYYGNYGAFRCLKEDMGDVAFLRSTALSDEHSEVYELLCPDNTRKPLNKYKECNLGTVPAGTVVTRKISDKTEDINNFLMEAQKRQCKLFSSAHGKDLMFDDSTLQLALLSSEVDAFLYLGVKLFHAMKALTGDAHLPSKNKVRWCTINKLEKMKCDDWSAVSGGAIACTEASCPKGCVKQILKGEADAVKLEVQYMYEALMCGLLPAVEEYHNKDDFGPCKTPGSPYTDFGTLRAVALVKKSNKDINWNNIKGSCHTGVGDIAGWVIPVSLIRRQNDNSDIDSFFGCAPGSDTKSNLCKLCKCSLSDKEAYYGNQGAFRCLVEKGDFVPHTVVFENTDGKNPAVWAKNLKSEDFELLCAPVSNSCKLSGIPPPAIVTREESISDVVRIVANQQSLYGRKGFEKDMFQLFSSNKGNNLLFNDNTQCLITFDRQPKDIMEDYFGKPYYTTVYGASRSAMSSELISACTIKHCSNSLEVL 6o0e B 2.50 BS01 9SL B 1 E540 Y558 F561 P727 F784 D785 Q787 D794 Y795 E525 Y543 F546 P710 F767 D768 Q770 D777 Y778 P31226 31223657 KQVRWCAISDLEQKKCNDLVGSCNVPDITLVCVLRSSTEDCMTAIKDGQADAMFLDSGEVYEASKDPYNLKPIIAEPYSSNRDLQKCLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKISGTNTPPGQTRATCERHELPKCLKERQVAVPQCDEKGNYEPQQFHGSTGYSWCVNAIGEEIAGTKTPPGKIPATCQKHDLVTTCHYAVAMVKKSSAFQFNQLKGKRSCHSGVSKTDGWKALVTVLVEKKLLSWDGPAKESIQRAMSKFFSVSCIPGATQTNLCKQCKGEEGKNCKNSHDEPYYGNYGAFRCLKEDMGDVAFLRSTALSDEHSEVYELLCPDNTRKPLNKYKECNLGTVPAGTVVTRKISDKTEDINNFLMEAQKRQCKLFSSAHGKDLMFDDSTLQLALLSSEVDAFLYLGVKLFHAMKALTGDAHLPSKNKVRWCTINKLEKMKCDDWSAVSGGAIACTEASCPKGCVKQILKGEADAVKLEVQYMYEALMCGLLPAVEEYHNKDDFGPCKTPGSPYTDFGTLRAVALVKNKDINWNNIKGKKSCHTGVGDIAGWVIPVSLIRRQNDNSDIDSFFGESCAPGSDTKSNLCKLCIGDPKNSAANTKCSLSDKEAYYGNQGAFRCLVEKGDVAFVPHTVVFENTDGKNPAVWAKNLKSEDFELLCLDGSRAPVSNYKSCKLSGIPPPAIVTREESISDVVRIVANQQSLYGRKGFEKDMFQLFSSNKGNNLLFNDNTQCLITFDRQPKDIMEDYFGKPYYTTVYGASRSAMSSELISACTIKHCSNSLEVL 6o0f A 2.12 BS01 9SL A 1 E540 Y558 F561 T563 P727 D785 R786 Q787 D794 Y795 E535 Y553 F556 T558 P705 D763 R764 Q765 D772 Y773 P31226 31223657 NAKQVRWCAISDLEQKKCNDLVGSCNVPDITLVCVLRSSTEDCMTAIKDGQADAMFLDSGEVYEASKDPYNLKPIIAEPYSSNRDLQKCLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKISGTNTPPGQTRATCERHELPKCLKERQVALGKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGEEIAGTKTPPGKIPATCQKHDLVTTCHYAVAMVKKSSAFQFNQLKGKRSCHSGVSKTDGWKALVTVLVEKKLLSWDGPAKESIQRAMSKFFSVSCIPGATQTNLCKQCKGEEGKNCKNSHDEPYYGNYGAFRCLKEDMGDVAFLRSTALSDEHSEVYELLCPDNTRKPLNKYKECNLGTVPAGTVVTRKISDKTEDINNFLMEAQKRQCKLFSSAHGKDLMFDDSTLQLALLSSEVDAFLYLGVKLFHAMKALTGDAHLPSKNKVRWCTINKLEKMKCDDWSAVSGGAIACTEASCPKGCVKQILKGEADAVKLEVQYMYEALMCGLLPAVEEYHNKDDFGPCKTPGSPYTDFGTLRAVALVKKSNKDINWNNIKGSCHTGVGDIAGWVIPVSLIRRQNDNSDIDSFFGCAPGSDTKSNLCKLCKCSLSDKEAYYGNQGAFRCLVEKGDFVPHTVVFENTDGKNPAVWAKNLKSEDFELLCLDGSRAPVSNYKSCKLSGIPPPAIVTREESISDVVRIVANQQSLYGRKGFEKDMFQLFSSNKGNNLLFNDNTQCLITFDRQPKDIMEDYFGKPYYTTVYGASRSAMSSELISACTIKHCSNSLEVLFQ 6o0f B 2.12 BS01 9SL B 1 E540 Y558 F561 T563 P727 F784 D785 Q787 D794 Y795 E526 Y544 F547 T549 P711 F768 D769 Q771 D778 Y779 P31226 31223657 KQVRWCAISDLEQKKCNDLVGSCNVPDITLVCVLRSSTEDCMTAIKDGQADAMFLDSGEVYEASKDPYNLKPIIAEPYSSNRDLQKCLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKISGTNTPPGQTRATCERHELPKCLKERQVAFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGEEIAGTKTPPGKIPATCQKHDLVTTCHYAVAMVKKSSAFQFNQLKGKRSCHSGVSKTDGWKALVTVLVEKKLLSWDGPAKESIQRAMSKFFSVSCIPGATQTNLCKQCKGEEGKNCKNSHDEPYYGNYGAFRCLKEDMGDVAFLRSTALSDEHSEVYELLCPDNTRKPLNKYKECNLGTVPAGTVVTRKISDKTEDINNFLMEAQKRQCKLFSSAHGKDLMFDDSTLQLALLSSEVDAFLYLGVKLFHAMKALTGDAHLPSKNKVRWCTINKLEKMKCDDWSAVSGGAIACTEASCPKGCVKQILKGEADAVKLEVQYMYEALMCGLLPAVEEYHNKDDFGPCKTPGSPYTDFGTLRAVALVKNKDINWNNIKGKKSCHTGVGDIAGWVIPVSLIRRQNDNSDIDSFFGESCAPGSDTKSNLCKLCIGDPKNSAANTKCSLSDKEAYYGNQGAFRCLVEKGDVAFVPHTVVFENTDGKNPAVWAKNLKSEDFELLCLDGSRAPVSNYKSCKLSGIPPPAIVTREESISDVVRIVANQQSLYGRKGFEKDMFQLFSSNKGNNLLFNDNTQCLITFDRQPKDIMEDYFGKPYYTTVYGASRSAMSSELISACTIKHCSNSLEVL 6o0x A 3.28 BS01 NUC B 1 K30 K33 L35 K44 N46 E57 T58 A59 E60 T62 R63 R66 R69 R70 R71 Y72 R74 R75 K76 N77 L101 S104 F105 K111 R115 H116 I122 E125 H129 T134 I135 H160 K163 F164 R165 G166 H167 F168 Y325 H328 H329 L332 K336 R340 F351 F352 Y359 Q402 R403 T404 F405 F446 R447 I448 Y450 G453 L455 A456 R457 N459 S460 F462 R467 T472 I473 P475 K510 Y515 N588 R661 K735 L738 K742 M1089 P1090 Q1091 E1099 V1100 T1102 G1103 G1104 F1105 I1110 P1112 R1122 K1124 Y1131 E1225 A1227 Q1272 Q1350 S1351 Y1356 E1357 K28 K31 L33 K42 N44 E55 T56 A57 E58 T60 R61 R64 R67 R68 R69 Y70 R72 R73 K74 N75 L99 S102 F103 K109 R113 H114 I120 E123 H127 T132 I133 H158 K161 F162 R163 G164 H165 F166 Y316 H319 H320 L323 K327 R331 F342 F343 Y350 Q393 R394 T395 F396 F437 R438 I439 Y441 G444 L446 A447 R448 N450 S451 F453 R458 T463 I464 P466 K501 Y506 N579 R652 K721 L724 K728 M835 P836 Q837 E845 V846 T848 G849 G850 F851 I856 P858 R868 K870 Y877 E971 A973 Q1018 Q1096 S1097 Y1102 E1103 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINAAKAILSARLSKSRRLENLIAQLKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0x A 3.28 BS02 NUC C 1 K1107 E1108 S1109 K1334 K853 E854 S855 K1080 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINAAKAILSARLSKSRRLENLIAQLKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0x A 3.28 BS03 NUC D 1 K1107 R1114 S1116 K1118 S1136 K1200 S1216 Q1221 R1333 R1335 K853 R860 S862 K864 S882 K946 S962 Q967 R1079 R1081 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINAAKAILSARLSKSRRLENLIAQLKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0x A 3.28 BS04 NUC c 1 L169 D269 Y450 I492 M495 N497 G582 T657 W659 M694 Q695 H698 L167 D260 Y441 I483 M486 N488 G573 T648 W650 M685 Q686 H689 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINAAKAILSARLSKSRRLENLIAQLKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0y A 3.37 BS01 NUC B 1 K3 S29 K30 K33 L35 K44 N46 E57 T58 A59 T62 R63 K65 R66 R69 R70 Y72 R74 R75 N77 L101 S104 F105 R115 H116 E125 H129 T134 I135 H160 K163 F164 R165 G166 Y325 H328 H329 K336 R340 F351 F352 Y359 I363 Q402 R403 T404 F405 G408 F446 R447 I448 Y450 P454 L455 A456 R457 N459 S460 F462 W464 R467 I473 P475 Y515 N588 R661 M694 P731 K734 K735 L738 Q739 K742 K749 R753 R765 S777 E779 Q807 Y812 D850 S851 I852 Y981 M1089 P1090 Q1091 V1100 T1102 G1103 F1105 I1110 P1112 R1122 K1123 K1124 Y1131 M1169 E1225 A1227 Q1272 H1349 Q1350 S1351 Y1356 K1 S27 K28 K31 L33 K42 N44 E55 T56 A57 T60 R61 K63 R64 R67 R68 Y70 R72 R73 N75 L99 S102 F103 R113 H114 E123 H127 T132 I133 H158 K161 F162 R163 G164 Y187 H190 H191 K198 R202 F213 F214 Y221 I225 Q264 R265 T266 F267 G270 F308 R309 I310 Y312 P316 L317 A318 R319 N321 S322 F324 W326 R329 I335 P337 Y377 N450 R523 M556 P588 K591 K592 L595 Q596 K599 K606 R610 R622 S634 E636 Q664 Y669 D707 S708 I709 Y835 M869 P870 Q871 V880 T882 G883 F885 I890 P892 R902 K903 K904 Y911 M949 E1005 A1007 Q1052 H1129 Q1130 S1131 Y1136 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSEAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0y A 3.37 BS02 NUC C 1 N863 S867 K1107 E1108 S1109 K1334 N720 S724 K887 E888 S889 K1114 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSEAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0y A 3.37 BS03 NUC D 1 K1107 R1114 S1116 D1135 S1136 S1216 E1219 Q1221 R1333 R1335 K887 R894 S896 D915 S916 S996 E999 Q1001 R1113 R1115 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSEAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0y A 3.37 BS04 NUC c 1 L169 Y450 N497 K526 G582 N588 E627 T657 W659 R661 N692 Q695 H698 R765 E766 Q774 S777 S834 D837 V838 D839 H840 N863 R951 L167 Y312 N359 K388 G444 N450 E489 T519 W521 R523 N554 Q557 H560 R622 E623 Q631 S634 S691 D694 V695 D696 H697 N720 R805 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSEAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0z A 3.30 BS01 NUC B 1 K30 K33 L35 R40 K44 N46 E57 A59 T62 R63 K65 R66 R69 R70 R71 R74 R75 K76 N77 L101 S104 F105 R115 H116 I122 E125 H129 T134 I135 H160 K163 F164 R165 G166 F168 Y325 H328 H329 L332 K336 R340 F351 F352 Y359 Q402 R403 T404 F405 N407 G408 F446 R447 I448 Y450 L455 A456 R457 N459 S460 F462 W464 R467 T472 I473 P475 H721 L738 K742 R753 P1090 Q1091 V1100 T1102 G1103 G1104 F1105 I1110 P1112 K1113 R1122 K1124 Y1131 M1169 E1225 A1227 Q1272 H1349 Q1350 S1351 Y1356 E1357 K28 K31 L33 R38 K42 N44 E55 A57 T60 R61 K63 R64 R67 R68 R69 R72 R73 K74 N75 L99 S102 F103 R113 H114 I120 E123 H127 T132 I133 H158 K161 F162 R163 G164 F166 Y316 H319 H320 L323 K327 R331 F342 F343 Y350 Q393 R394 T395 F396 N398 G399 F437 R438 I439 Y441 L446 A447 R448 N450 S451 F453 W455 R458 T463 I464 P466 H675 L692 K696 R707 P1012 Q1013 V1022 T1024 G1025 G1026 F1027 I1032 P1034 K1035 R1044 K1046 Y1053 M1091 E1147 A1149 Q1194 H1271 Q1272 S1273 Y1278 E1279 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIDLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIEASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRKTILDFLKSNRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARRMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYKVYDVRKMIYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0z A 3.30 BS02 NUC C 1 Y450 N497 W659 R661 R925 Q926 K1107 E1108 S1109 K1334 Y441 N488 W627 R629 R863 Q864 K1029 E1030 S1031 K1256 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIDLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIEASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRKTILDFLKSNRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARRMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYKVYDVRKMIYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o0z A 3.30 BS03 NUC D 1 R1114 S1116 K1118 S1136 P1137 K1200 S1216 Q1221 R1333 R1335 R1036 S1038 K1040 S1058 P1059 K1122 S1138 Q1143 R1255 R1257 3.1.-.- Q99ZW2 KKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIDLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIEASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRKTILDFLKSNRNFMQLIHDDSLTFKEDIQKAQDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARRMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYKVYDVRKMIYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG 6o43 A 2.08 BS01 I3C A 1 W46 R93 G94 D95 Y96 W38 R85 G86 D87 Y88 Q859J2 NDQEKIDKFTHSYINDDFGLTIDQLVPKVKGYGRFNVWLGGNESKIRQVLKAVKEIGVSPTLFAVYEKNEGFSSGLGWLNHTSARGDYLTDAKFIARKLVSQSKQAGQPSWYDAGNIVHFVPQDVQRKGNADFAKNMKAGTIGRAYIPLTAAATWAAYYPLGLKASYNKVQNYGNPFLDGANTILAWGGKLDGKGGSPS 6o5m B 2.30 BS03 G8K B 1 V236 C239 L240 L246 A248 L253 N256 V313 A314 A315 I316 N347 N348 K350 A352 I368 V235 C238 L239 L245 A247 L252 N255 V312 A313 A314 I315 N346 N347 K349 A351 I367 A0A287AGU7 31251599 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6o5m D 2.30 BS02 G8K D 1 V236 C239 L240 L246 A248 K252 L253 N256 M257 V313 A314 A315 I316 N347 N348 K350 A352 I368 V236 C239 L240 L246 A248 K252 L253 N256 M257 V303 A304 A305 I306 N337 N338 K340 A342 I358 A0A287AGU7 31251599 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6o5m F 2.30 BS02 ACP F 1 K74 I148 Q183 K184 Y185 L186 K198 R202 R222 T241 D318 I330 E331 N333 K74 I122 Q145 K146 Y147 L148 K160 R164 R184 T203 D276 I288 E289 N291 E1BQ43 31251599 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPREVFLAAYNRRREGRGNVWIALISSEASELDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLSIFIKLHH 6o5n B 3.00 BS03 QW9 B 1 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 V313 A314 N348 K350 A352 V235 C238 L239 L245 A247 D248 K251 L252 N255 M256 V312 A313 N347 K349 A351 A0A287AGU7 31251599 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6o5n D 3.00 BS02 QW9 D 1 V236 C239 L240 A248 D249 K252 L253 N256 M257 V313 I316 N348 K350 A352 V236 C239 L240 A248 D249 K252 L253 N256 M257 V303 I306 N338 K340 A342 A0A287AGU7 31251599 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6o61 B 2.60 BS03 KUM B 1 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 V313 A314 I316 N348 K350 I368 V235 C238 L239 L245 A247 D248 K251 L252 N255 M256 V312 A313 I315 N347 K349 I367 A0A287AGU7 31251599 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6o61 F 2.60 BS01 ACP F 1 K74 Q183 K184 Y185 L186 K198 T241 D318 E331 N333 K74 Q143 K144 Y145 L146 K158 T192 D263 E276 N278 E1BQ43 31251599 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPREVFLAAYNRRREGREGNVWILISSEASELLDFIDEVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSLTNHCINYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 6ofk A 1.15 BS01 CRO A 1 V11 T12 T13 L14 V18 Q19 Q44 R46 N71 F95 H98 V100 F115 T153 E172 L235 L237 F239 V10 T11 T12 L13 V14 Q15 Q40 R42 N67 F91 H94 V96 F111 T149 E168 L219 L221 F223 KLPVPWPTLVTTLVQCFSRYPDHMKRHDFFKSAMPEGYVQERTISFKDDGKYKTRAVVKFEGDTLVNRIELKGTDFKEDGNILGHKLEYNFNSHNVYITADKQKNGIKANFTVRHNVEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQTVLSKDPNEKRDHMVLLEFVTAAGIGSASQGEELFTGVVPILVELDGDVNGHKFSVRGEGEGDATIGKLTLKFIS 6om3 G 3.30 BS01 NUC I 1 A12 A14 K15 R17 G28 R32 R77 A1 A3 K4 R6 G17 R21 R66 Q6AZJ8 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6om3 S 3.30 BS01 NUC U 1 A12 A14 K15 T16 R17 R32 R42 R77 A1 A3 K4 T5 R6 R21 R31 R66 Q6AZJ8 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6om3 T 3.30 BS01 NUC U 1 T32 R33 Y42 G53 S56 R86 S87 T88 T1 R2 Y11 G22 S25 R55 S56 T57 P02281 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6opc A 3.70 BS01 III G 1 K287 M288 M560 W561 Y562 A603 K257 M258 M530 W531 Y532 A570 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQM 6opc A 3.70 BS02 ADP A 1 G490 G531 T532 G533 K534 T535 L536 I666 Q670 L698 G460 G501 T502 G503 K504 T505 L506 I633 Q637 L665 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQM 6opc A 3.70 BS03 BEF A 1 P530 G531 K534 N634 P500 G501 K504 N601 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQM 6opc A 3.70 BS04 ADP A 2 D215 G258 T259 G260 K261 T262 L263 V390 H394 G418 D185 G228 T229 G230 K231 T232 L233 V360 H364 G388 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQM 6opc A 3.70 BS05 BEF A 2 P256 P257 G258 K261 P226 P227 G228 K231 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQM 6opc B 3.70 BS02 BEF A 1 R645 R648 R615 R618 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc B 3.70 BS04 MG B 1 T535 D587 T505 D557 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc B 3.70 BS05 ADP B 2 D215 G258 T259 G260 K261 T262 L263 H394 G418 A419 D185 G228 T229 G230 K231 T232 L233 H364 G388 A389 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc B 3.70 BS06 BEF B 1 P257 G258 K261 T262 N358 P227 G228 K231 T232 N328 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc B 3.70 BS07 BEF C 1 P530 G531 N634 P500 G501 N604 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc C 3.70 BS01 III G 1 K287 M560 W561 Y562 A603 K257 M530 W531 Y532 A573 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc C 3.70 BS03 ADP C 1 G531 T532 G533 K534 T535 L536 I666 Q670 G694 L698 G501 T502 G503 K504 T505 L506 I636 Q640 G664 L668 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc C 3.70 BS04 BEF C 2 P530 K534 T535 P500 K504 T505 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc D 3.70 BS01 III G 1 M288 M560 W561 Y562 D602 A603 M258 M530 W531 Y532 D572 A573 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc D 3.70 BS02 ADP C 1 D619 R645 D589 R615 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc D 3.70 BS04 ADP D 1 V489 G490 G531 T532 G533 T535 L536 I666 Q670 G694 L698 V459 G460 G501 T502 G503 T505 L506 I636 Q640 G664 L668 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc D 3.70 BS05 BEF D 1 P530 T535 P500 T505 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc D 3.70 BS07 BEF D 2 P256 P257 G258 K261 N358 P226 P227 G228 K231 N328 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc E 3.70 BS01 III G 1 K287 M288 N327 M560 W561 Y562 K257 M258 N297 M518 W519 Y520 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc E 3.70 BS04 ADP E 1 D488 G490 P530 G531 T532 G533 K534 T535 L536 I666 Q670 G694 A695 L698 D446 G448 P488 G489 T490 G491 K492 T493 L494 I624 Q628 G652 A653 L656 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6opc E 3.70 BS05 ADP E 2 D215 G217 G258 T259 G260 T262 L263 H394 A419 D185 G187 G228 T229 G230 T232 L233 H364 A389 3.6.4.6 P25694 31249134 KKDNMLLVDDAINDDNSVIAINSNTMDKLELFRGDTVLVKGKKRKDTVLIVLIDDELEDGACRINRVVRNNLRIRLGDLVTIHPCPDIKYATRISVLPIADTIEGITGNLFDVFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKVVDVEPEEYAVVAQDTIIHWEGEPINREDEENNMNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFFLINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDVDLEALAAETHGYVGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKTPLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMKASRGQFSNFNF 6oq5 A 3.87 BS01 ZN A 1 D547 H654 C699 H758 D546 H653 C698 H757 M4NKV9 SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEGALGEDDNLDFSQNTVTDKEYLLEKISSSTKSSERGYVHYIVQLQGDKISYEAACNLFAKNPYDSILFQKNIEDSEVAYYYNPTDSEIQEIDKYRIPDRISDRPKIKLTFIGHGKAEFNTDIFAGLDVDSLSSEIETAIGLAKEDISPKSIEINLLGCNMFSYSVNVEETYPGKLLLRVKDKVSELMPSMSQDSIIVSANQYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKIIVKSKNLPELSTLLQEIRNNSNSSDIELEEKVMLAECEINVISNIETQVVEERIEEAKSLTSDSINYIKNEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETEKTIFSEYANHITEEISKIKGTIFDTVNGNLDTTHEVNTLNAAFFIQSLIEYNSSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLPELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGIASGFSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKVMMPQDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYDVLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEFYWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSGGTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIEENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKILMLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLISKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKLNSVHLDESGVAEILKFMNRKGSTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANFIISGTTSIGQFEFICDENNNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGDISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYINEKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNFSDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSLYYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFSTEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFEDNYRGAVEWKELDGEMHYFSPETGKAFKGLNQIGDDKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKHFYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFTAVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFSDSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSGLVRVGEDVYYFGETYTIETGWIYDMENESDKYYFDPETKKACKGINLIDDIKYYFDEKGIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFAHQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVISEHH 6oq5 A 3.87 BS02 MG A 1 D286 D288 E516 L520 D285 D287 E515 L519 M4NKV9 SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEGALGEDDNLDFSQNTVTDKEYLLEKISSSTKSSERGYVHYIVQLQGDKISYEAACNLFAKNPYDSILFQKNIEDSEVAYYYNPTDSEIQEIDKYRIPDRISDRPKIKLTFIGHGKAEFNTDIFAGLDVDSLSSEIETAIGLAKEDISPKSIEINLLGCNMFSYSVNVEETYPGKLLLRVKDKVSELMPSMSQDSIIVSANQYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKIIVKSKNLPELSTLLQEIRNNSNSSDIELEEKVMLAECEINVISNIETQVVEERIEEAKSLTSDSINYIKNEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETEKTIFSEYANHITEEISKIKGTIFDTVNGNLDTTHEVNTLNAAFFIQSLIEYNSSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLPELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGIASGFSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKVMMPQDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYDVLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEFYWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSGGTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIEENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKILMLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLISKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKLNSVHLDESGVAEILKFMNRKGSTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANFIISGTTSIGQFEFICDENNNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGDISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYINEKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNFSDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSLYYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFSTEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFEDNYRGAVEWKELDGEMHYFSPETGKAFKGLNQIGDDKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKHFYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFTAVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFSDSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSGLVRVGEDVYYFGETYTIETGWIYDMENESDKYYFDPETKKACKGINLIDDIKYYFDEKGIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFAHQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVISEHH 6oq7 A 2.39 BS01 UDP A 1 I101 W102 I103 N139 L265 A266 S269 Y284 D286 V287 D288 E516 S519 L520 W521 I100 W101 I102 N138 L264 A265 S268 Y283 D285 V286 D287 E515 S518 L519 W520 M4NKV9 SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEG 6oq7 A 2.39 BS02 GLC A 1 A266 D270 R273 D286 I384 N385 T466 I467 G471 A265 D269 R272 D285 I383 N384 T465 I466 G470 M4NKV9 SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEG 6oq7 A 2.39 BS03 MN A 1 D288 E516 D287 E515 M4NKV9 SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEG 6oq7 A 2.39 BS04 MG A 1 D288 Q515 N518 D287 Q514 N517 M4NKV9 SLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVEKYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVIEILELKNSNLTPVEKNLHFIWIGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFRENLNDPEFNHTAFFRKRMQIIYDKQQNFINYYKAQKEENPDLIIDDIVKTYLSNEYSKDIDELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAILKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKHKEYIPEYTSKHFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAKDSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAKIGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVNISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEG 6or4 A 2.10 BS01 FUC A 1 F26 H28 W39 H77 H78 Y123 W169 N171 A173 Q215 D257 W264 F24 H26 W37 H75 H76 Y121 W167 N169 A171 Q213 D255 W262 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6or4 A 2.10 BS02 GAL A 1 W169 N171 G172 A173 F202 W211 Q215 D257 W167 N169 G170 A171 F200 W209 Q213 D255 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6or4 B 2.10 BS02 GAL B 1 W169 N171 G172 A173 W211 Q215 D257 W167 N169 G170 A171 W209 Q213 D255 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6orf A 1.70 BS01 FUC A 1 H28 W39 H77 H78 Y123 N171 A173 D257 W264 H26 W37 H75 H76 Y121 N169 A171 D255 W262 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6orf A 1.70 BS02 GAL A 1 W169 N171 G172 A173 F202 W211 D257 W167 N169 G170 A171 F200 W209 D255 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6orf B 1.70 BS02 GAL B 1 W169 N171 G172 A173 F202 T204 W211 D257 W167 N169 G170 A171 F200 T202 W209 D255 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6org A 1.72 BS01 CA A 1 H346 D349 L351 S354 T443 H345 D348 L350 S353 T442 A0A0H2US78 KKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6orh A 1.62 BS01 FUC A 1 H28 W39 H77 H78 Y123 N171 A173 Q215 D257 W264 H26 W37 H75 H76 Y121 N169 A171 Q213 D255 W262 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6orh A 1.62 BS02 GAL A 1 W169 N171 G172 T204 W211 Q215 D257 W167 N169 G170 T202 W209 Q213 D255 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6orh A 1.62 BS03 FUC A 2 G172 A173 T234 G170 A171 T232 A0A0H2US78 KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMNGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNQRGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTP 6os9 R 3.00 BS01 III L 1 E53 L54 F127 H131 Y145 M207 V223 T225 R322 R323 F326 W334 Y339 Y342 H343 Y346 E4 L5 F78 H82 Y96 M158 V174 T176 R253 R254 F257 W265 Y270 Y273 H274 Y277 P30989 31243364 PSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTLFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIF 6osa R 3.00 BS01 III L 1 E53 L54 F127 H131 Y145 M207 V223 T225 R323 F326 D331 W334 Y339 Y342 H343 Y346 E4 L5 F78 H82 Y96 M158 V174 T176 R261 F264 D269 W272 Y277 Y280 H281 Y284 P30989 31243364 PSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTLFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQCTVGGPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLC 6oyh A 2.95 BS01 NK4 A 1 K70 T75 F180 G184 N187 N190 L191 D193 G194 L195 D196 F262 G264 T299 H324 H325 K41 T46 F151 G155 N158 N161 L162 D164 G165 L166 D167 F233 G235 T270 H292 H293 2.7.8.13 O66465 FAFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6oyh C 2.95 BS01 NK4 C 1 K70 T75 F180 G184 N187 N190 L191 D193 G194 L195 D196 F262 M263 G264 D265 T299 P322 H324 H325 K40 T45 F150 G154 N157 N160 L161 D163 G164 L165 D166 F232 M233 G234 D235 T269 P292 H294 H295 2.7.8.13 O66465 FAFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRLFKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6oyh B 2.95 BS01 NK4 B 1 K70 T75 F180 G184 N190 L191 D193 G194 L195 D196 F262 G264 S268 T299 V302 R320 P322 H324 H325 K42 T47 F152 G156 N162 L163 D165 G166 L167 D168 F234 G236 S240 T271 V274 R292 P294 H296 H297 2.7.8.13 O66465 WFAFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRLFKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6oyh D 2.95 BS01 NK4 D 1 K70 T75 F180 N190 D193 G194 L195 D196 N255 F262 M263 G264 D265 T299 R320 P322 H324 H325 K49 T54 F159 N169 D172 G173 L174 D175 N234 F241 M242 G243 D244 T278 R299 P301 H303 H304 2.7.8.13 O66465 AFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQRVREYTPHEVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRLFKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6oyz A 3.62 BS01 NKM A 1 K70 T75 K121 K125 D193 G194 L195 D196 F262 M263 G264 D265 K34 T39 K85 K89 D157 G158 L159 D160 F226 M227 G228 D229 2.7.8.13 O66465 YITFRSFTAVLIAFFLTLVLSPSFINRLRKIQRKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6oz6 A 3.70 BS01 NKD A 1 T75 N190 L191 D193 G194 L195 D196 F262 M263 G264 D265 V302 A321 H325 T48 N163 L164 D166 G167 L168 D169 F235 M236 G237 D238 V275 A294 H298 2.7.8.13 O66465 AFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQRLFGKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRLFKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6oz6 B 3.70 BS01 NKD B 1 K70 T75 N190 L191 D193 G194 L195 D196 F262 G264 V302 A321 H325 K43 T48 N159 L160 D162 G163 L164 D165 F231 G233 V271 A285 H289 2.7.8.13 O66465 YWFAFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNSIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLK 6oz6 C 3.70 BS01 NKD C 1 T75 N190 L191 D193 G194 L195 D196 N255 F262 D265 V302 Q305 A321 P322 H325 T46 N154 L155 D157 G158 L159 D160 N219 F226 D229 V266 Q269 A285 P286 H289 2.7.8.13 O66465 DYWFAFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRLFKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL 6p25 A 3.20 BS01 CPL A 1 P565 I597 G598 I599 F600 I631 L634 F637 A638 Y641 A642 F645 P547 I579 G580 I581 F582 I613 L616 F619 A620 Y623 A624 F627 2.4.1.109 P33775 PVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNSLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKR 6p25 A 3.20 BS02 NNM A 1 H98 K234 W235 L238 F239 V241 T242 G245 L252 A270 K273 L274 L277 L278 W545 N548 M647 R649 H654 H655 H84 K220 W221 L224 F225 V227 T228 G231 L238 A256 K259 L260 L263 L264 W527 N530 M629 R631 H636 H637 2.4.1.109 P33775 PVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNSLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKR 6p25 A 3.20 BS03 CPL B 1 I249 I256 L259 S263 I266 F267 A270 I235 I242 L245 S249 I252 F253 A256 2.4.1.109 P33775 PVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNSLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKR 6p25 B 3.20 BS01 III D 1 W91 D92 H95 S138 L576 L592 C593 Y674 W35 D36 H39 S82 L512 L528 C529 Y610 2.4.1.109 P31382 SSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSNFRYLNWFSTWDIA 6p25 B 3.20 BS02 CPL B 1 V626 I627 I630 R631 R634 Y636 V562 I563 I566 R567 R570 Y572 2.4.1.109 P31382 SSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSNFRYLNWFSTWDIA 6p25 B 3.20 BS03 CPL B 2 A613 V616 L619 A620 A623 T624 I627 L628 R631 D638 R640 L689 Y691 C692 G696 K699 A549 V552 L555 A556 A559 T560 I563 L564 R567 D574 R576 L625 Y627 C628 G632 K635 2.4.1.109 P31382 SSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSNFRYLNWFSTWDIA 6p2r A 3.20 BS01 CPL A 1 T562 F566 T594 I597 G598 I599 I631 L634 F637 A638 Y641 A642 T544 F548 T576 I579 G580 I581 I613 L616 F619 A620 Y623 A624 2.4.1.109 P33775 PVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNSLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKR 6p2r A 3.20 BS02 NNM A 1 H98 K234 W235 L238 F239 T242 G245 C248 L252 L274 L277 L278 W545 N548 M647 R649 H654 H655 H84 K220 W221 L224 F225 T228 G231 C234 L238 L260 L263 L264 W527 N530 M629 R631 H636 H637 2.4.1.109 P33775 PVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNSLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKR 6p2r A 3.20 BS03 CPL B 1 I256 L259 S263 I266 F267 A270 F271 I242 L245 S249 I252 F253 A256 F257 2.4.1.109 P33775 PVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIPQNVVADVGIGSIISLRHLSTMGGYLHSHSHNYPAGSEQQQSTLYPHMDANNDWLLELYNSLTTFQNLTDGTKVRLFHTVTRCRLHSHDHKPPVSESSDWQKEVSCYGYSGFDGDANDDWVVEIDKKNSAPGVAQERVIALDTKFRLRHAMTGCYLFSHEVKLPAWGFEQQEVTCASSGRHDLTLWYVENNSNPLLPEDTKRISYKPASFISKFIESHKKMWHINKNLVEPHVYESQPTSWPFLLRGISYWGENNRNVYLLGNAIVWWAVTAFIGIFGLIVITELFSWQLGKPILKDSKVVNFHVQVIHYLLGFAVHYAPSFLMQRQMFLHHYLPAYYFGILALGHALDIIVSYVFRSKRQMGYAVVITFLAASVYFFKSFSPIIYGTPWTQELCQKSQWLSGWDYNCNTYFSSLEEYKNQTLTKR 6p2r B 3.20 BS02 CPL B 2 V616 L619 A620 A623 T624 I627 L628 R631 D638 R640 L689 Y691 C692 F693 K699 V552 L555 A556 A559 T560 I563 L564 R567 D574 R576 L625 Y627 C628 F629 K635 2.4.1.109 P31382 SSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSNFRYLNWFSTWDIA 6p81 A 1.75 BS01 III B 1 R152 T172 G174 H175 R176 L177 P242 V360 M362 P363 M364 R365 R228 T248 G250 H251 R252 L253 P316 V434 M436 P437 M438 R439 W1BGQ6 ETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGMKFTVEREHLLKPLQQVSGPGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 6p81 A 1.75 BS02 CA A 1 E6 G85 E87 E84 G161 E163 W1BGQ6 ETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGMKFTVEREHLLKPLQQVSGPGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 6pi9 A 1.85 BS01 SAH A 1 I54 T55 F58 S91 R95 A120 C121 D140 I141 C165 D166 L167 M182 Q191 I55 T56 F59 S92 R96 A121 C122 D141 I142 C166 D167 L168 M183 Q192 2.1.1.179 I1YZZ5 GMDERAQAALDALLSAKNLRDVCPETVRRVFMELLPRYRKPKDAEKAARTHLHQITGAFMTADAQKKARALLARWNEGDESALAAALSLHASTRERLPGADEWMRRVSPFLGADARVLDLACGLNPILLGSMGVTNALGMDIHLGCVRLVNETARARGWHTRARACDLLSEIPAEEADAALLMKLLPVLEAQKTGRAAELLASLRAPRLVVTFPTRTLGGRGVGMEKHYADWFERILPDTLSVRDRFTVSDELVYLVERT 6q45 A 3.60 BS01 ATP A 1 R171 Q172 T173 G174 K175 T176 A177 F349 R354 Q422 Q424 R147 Q148 T149 G150 K151 T152 A153 F325 R330 Q398 Q400 Q8RGE0 31238823 IKTSGTVLEVGDGIARIFGLSNVMSGELLEFPHGVMGMALNLEEDNVGAVILGNASLIKEGDEVRATGKVVSVPAGEDLLGRVINALGDPIDGKGEIHVDKYMPIERKASGIIARQPVSEPLQTGIKSIDGMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVKCIYVAIGQKRSTVAQIYKKLSDLGCMDYTIIVAATASEAAPLQYMAPYSGVAIGEYFMEKGEHVLIIYDDLSKHAVAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESQLFNSGFRPAINAGISVSRVGGAAQIKAMKQVASKVKLELAQYTELLTFAQFGSDLDKATKAQLERGHRIMEILKQPQYHPFAVERQVVSFYIVINGHLDDIEVSKVRRFEKELLDYLKANTNILTEIADKKALDKDLEEKLKESIANFKKSFN 6q45 B 3.60 BS01 ATP B 1 Q172 T173 G174 K175 T176 A177 E320 F349 R354 Q424 Q146 T147 G148 K149 T150 A151 E294 F323 R328 Q398 Q8RGE0 31238823 TSGTVLEVGDGIARIFGLSNVMSGELLEFPHGVMGMALNLEEDNVGAVILGNASLIKEGDEVRATGKVVSVPAGEDLLGRVINALGDPIDGKGEIHVDKYMPIERKASGIIARQPVSEPLQTGIKSIDGMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVKCIYVAIGQKRSTVAQIYKKLSDLGCMDYTIIVAATASEAAPLQYMAPYSGVAIGEYFMEKGEHVLIIYDDLSKHAVAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESQLFNSGFRPAINAGISVSRVGGAAQIKAMKQVASKVKLELAQYTELLTFAQFGSDLDKATKAQLERGHRIMEILKQPQYHPFAVERQVVSFYIVINGHLDDIEVSKVRRFEKELLDYLKANTNILTEIADKKALDKDLEEKLKESIANFKKSFN 6q45 C 3.60 BS02 ADP D 1 S364 R365 S340 R341 Q8RGE0 31238823 IKTSGTVLEVGDGIARIFGLSNVMSGELLEFPHGVMGMALNLEEDNVGAVILGNASLIKEGDEVRATGKVVSVPAGEDLLGRVINALGDPIDGKGEIHVDKYMPIERKASGIIARQPVSEPLQTGIKSIDGMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVKCIYVAIGQKRSTVAQIYKKLSDLGCMDYTIIVAATASEAAPLQYMAPYSGVAIGEYFMEKGEHVLIIYDDLSKHAVAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESQLFNSGFRPAINAGISVSRVGGAAQIKAMKQVASKVKLELAQYTELLTFAQDKATKAQLERGHRIMEILKQPQYHPFAVERQVVSFYIVINGHLDDIEVSKVRRFEKELLDYLKANTNILTEIADKKALDKDLEEKLKESIANFKKSFN 6q45 D 3.60 BS01 ADP D 1 G150 G152 V153 G154 K155 T156 V157 Y332 F405 A408 F411 G150 G152 V153 G154 K155 T156 V157 Y332 F405 A408 F411 Q8RGE2 31238823 MNKGTITQIISAVVDIAFKDELPAIYNALKVKLEDKELVLEVEQHLGNNVVRTVAMDSTDGLKRGMEVIDTGKPITIPVGKAVLGRILNVLGEPVDNQGPLNAETFLPIHREAPEFDDLETETEIFETGIKVIDLLAPYIKGGKIGLFGGAGVGKTVLIMELINNIAKGHGGISVFAGVGERTREGRDLYGEMTESGVITKTALVYGQMNEPPGARLRVALTGLTVAENFRDKDGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPNLATEMGALQERITSTKSGSITSVQAVYVPADDLTDPAPATTFSHLDATTVLSRNIASLGIYPAVDPLDSTSKALSEDVVGKEHYEVARKVQEVLQRYKELQDIIAILGMDELSDEDKLTVSRARKIERFFSQPFSVAEQFTGMEGKYVPVKETIRGFREILEGKHDDIPEQAFLYVGTIEEAVAKSKDL 6q45 D 3.60 BS02 MG D 1 T156 R182 T156 R182 Q8RGE2 31238823 MNKGTITQIISAVVDIAFKDELPAIYNALKVKLEDKELVLEVEQHLGNNVVRTVAMDSTDGLKRGMEVIDTGKPITIPVGKAVLGRILNVLGEPVDNQGPLNAETFLPIHREAPEFDDLETETEIFETGIKVIDLLAPYIKGGKIGLFGGAGVGKTVLIMELINNIAKGHGGISVFAGVGERTREGRDLYGEMTESGVITKTALVYGQMNEPPGARLRVALTGLTVAENFRDKDGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPNLATEMGALQERITSTKSGSITSVQAVYVPADDLTDPAPATTFSHLDATTVLSRNIASLGIYPAVDPLDSTSKALSEDVVGKEHYEVARKVQEVLQRYKELQDIIAILGMDELSDEDKLTVSRARKIERFFSQPFSVAEQFTGMEGKYVPVKETIRGFREILEGKHDDIPEQAFLYVGTIEEAVAKSKDL 6q45 F 3.60 BS01 ADP F 1 G150 G152 V153 G154 K155 T156 V157 Y332 F405 G150 G152 V153 G154 K155 T156 V157 Y332 F405 Q8RGE2 31238823 MNKGTITQIISAVVDIAFKDELPAIYNALKVKLEDKELVLEVEQHLGNNVVRTVAMDSTDGLKRGMEVIDTGKPITIPVGKAVLGRILNVLGEPVDNQGPLNAETFLPIHREAPEFDDLETETEIFETGIKVIDLLAPYIKGGKIGLFGGAGVGKTVLIMELINNIAKGHGGISVFAGVGERTREGRDLYGEMTESGVITKTALVYGQMNEPPGARLRVALTGLTVAENFRDKDGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPNLATEMGALQERITSTKSGSITSVQAVYVPADDLTDPAPATTFSHLDATTVLSRNIASLGIYPAVDPLDSTSKALSEDVVGKEHYEVARKVQEVLQRYKELQDIIAILGMDELSDEDKLTVSRARKIERFFSQPFSVAEQFTGMEGKYVPVKETIRGFREILEGKHDDIPEQAFLYVGTIEEAVAKSKDLAK 6q45 J 3.60 BS01 ATP J 1 Q172 T173 G174 K175 T176 A177 E320 F349 R354 Q422 P423 Q424 Q147 T148 G149 K150 T151 A152 E295 F324 R329 Q391 P392 Q393 Q8RGE0 31238823 KTSGTVLEVGDGIARIFGLSNVMSGELLEFPHGVMGMALNLEEDNVGAVILGNASLIKEGDEVRATGKVVSVPAGEDLLGRVINALGDPIDGKGEIHVDKYMPIERKASGIIARQPVSEPLQTGIKSIDGMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVKCIYVAIGQKRSTVAQIYKKLSDLGCMDYTIIVAATASEAAPLQYMAPYSGVAIGEYFMEKGEHVLIIYDDLSKHAVAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESQLFNSGFRPAINAGISVSRVGGAAQIKAMKQVASKVKLELAQYTELLTFAQKATKAQLERGHRIMEILKQPQYHPFAVERQVVSFYIVINGHLDDIEVSKVRRFEKELLDYLKANTNILTEIADKKALDKDLEEKLKESIANFKKSFN 6q45 K 3.60 BS01 ATP K 1 Q172 T173 G174 K175 T176 A177 F349 R354 Q424 Q146 T147 G148 K149 T150 A151 F323 R328 Q395 Q8RGE0 31238823 TSGTVLEVGDGIARIFGLSNVMSGELLEFPHGVMGMALNLEEDNVGAVILGNASLIKEGDEVRATGKVVSVPAGEDLLGRVINALGDPIDGKGEIHVDKYMPIERKASGIIARQPVSEPLQTGIKSIDGMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQDVKCIYVAIGQKRSTVAQIYKKLSDLGCMDYTIIVAATASEAAPLQYMAPYSGVAIGEYFMEKGEHVLIIYDDLSKHAVAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESQLFNSGFRPAINAGISVSRVGGAAQIKAMKQVASKVKLELAQYTELLTFAQFGSKATKAQLERGHRIMEILKQPQYHPFAVERQVVSFYIVINGHLDDIEVSKVRRFEKELLDYLKANTNILTEIADKKALDKDLEEKLKESIANF 6q58 B 1.50 BS03 CU1 B 3 C41 C57 D61 C104 C117 C23 C39 D43 C86 C99 Q9X8F4 31111982 VDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGL 6q58 B 1.50 BS04 CU1 B 4 C57 D61 C104 C39 D43 C86 Q9X8F4 31111982 VDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGL 6q6b B 1.90 BS01 CU1 B 1 D61 C100 C104 C117 C121 D43 C82 C86 C99 C103 Q9X8F4 31111982 VDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGLG 6q6b C 1.90 BS10 CU1 C 10 D61 C100 C104 C117 D42 C81 C85 C98 Q9X8F4 31111982 DREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGL 6q6b C 1.90 BS11 CU1 C 11 C38 D61 C64 C100 C117 C121 C19 D42 C45 C81 C98 C102 Q9X8F4 31111982 DREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGL 6q6b A 1.90 BS03 CU1 A 3 C41 C45 C57 D61 C114 C38 C42 C54 D58 C111 Q9X8F4 31111982 TVNDLLRTYPADLGGVDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGL 6q6b A 1.90 BS09 CU1 A 9 C34 C38 C64 C97 C100 C121 C31 C35 C61 C94 C97 C118 Q9X8F4 31111982 TVNDLLRTYPADLGGVDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGL 6q6b D 1.90 BS03 CU1 D 3 C41 C57 D61 C104 C114 C117 C22 C38 D42 C85 C95 C98 Q9X8F4 31111982 DREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMHEHCRVCAEACRSCEQACQELLAGLG 6qf2 A 1.73 BS06 LEU A 1 N112 A113 F130 L133 V139 H142 E143 I188 L202 R203 H231 N112 A113 F130 L133 V139 H142 E143 I188 L202 R203 H231 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6qf3 A 1.52 BS07 NA A 2 T276 S279 Q283 T276 S279 Q283 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6qf3 A 1.52 BS08 NA A 3 H146 T149 D150 N165 H146 T149 D150 N165 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6qf3 A 1.52 BS09 ASP A 1 N112 A113 F114 H142 E143 H146 Y157 E166 H231 N112 A113 F114 H142 E143 H146 Y157 E166 H231 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6qf4 A 2.50 BS01 MG A 1 N163 D179 N146 D162 2.7.11.1 O94768 ENLYFQSMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETS 6qf4 A 2.50 BS02 ADP A 1 A60 K62 I94 L110 E111 Y112 A113 E117 Q162 N163 L165 D179 A43 K45 I77 L93 E94 Y95 A96 E100 Q145 N146 L148 D162 2.7.11.1 O94768 ENLYFQSMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETS 6qfd A 2.13 BS01 NUC E 1 N49 H50 G51 R52 N56 K73 R74 N43 H44 G45 R46 N50 K67 R68 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd A 2.13 BS02 NUC F 1 Y32 G33 L34 H50 G51 Y54 P55 K68 R74 T75 N76 Y26 G27 L28 H44 G45 Y48 P49 K62 R68 T69 N70 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd A 2.13 BS03 MN A 1 K37 H50 K31 H44 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd A 2.13 BS04 MN A 2 E41 E47 E35 E41 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd B 2.13 BS02 NUC F 1 N49 H50 G51 R52 N56 D72 K73 R74 N44 H45 G46 R47 N51 D67 K68 R69 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd B 2.13 BS03 MN B 1 R9 R13 D90 D91 R4 R8 D85 D86 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd B 2.13 BS04 MN B 2 K37 N49 H50 K32 N44 H45 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd B 2.13 BS05 MN B 3 T16 F18 Q19 N56 T11 F13 Q14 N51 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd C 2.13 BS03 MN C 1 K37 E47 N49 H50 K28 E38 N40 H41 Q9HSF4 SDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qfd C 2.13 BS04 MN C 2 T81 N82 E83 T72 N73 E74 Q9HSF4 SDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil A 2.00 BS02 NUC F 1 T16 N49 H50 G51 R52 N56 K73 R74 T10 N43 H44 G45 R46 N50 K67 R68 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil A 2.00 BS04 MN A 2 N21 Y43 N15 Y37 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil A 2.00 BS05 MN A 3 E110 A114 E104 A108 Q9HSF4 DARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil B 2.00 BS01 NUC E 1 T16 N49 H50 G51 R52 N56 D72 K73 R74 T11 N44 H45 G46 R47 N51 D67 K68 R69 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil B 2.00 BS03 MN A 4 R13 K20 R8 K15 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil B 2.00 BS04 MN A 5 R106 E110 R101 E105 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil C 2.00 BS01 NUC G 1 T16 H50 G51 R52 N56 D72 K73 R74 T7 H41 G42 R43 N47 D63 K64 R65 Q9HSF4 SDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil C 2.00 BS03 MN C 1 K37 E47 V48 N49 H50 K28 E38 V39 N40 H41 Q9HSF4 SDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qil C 2.00 BS04 MN C 2 Y54 L57 D58 Y78 Y45 L48 D49 Y69 Q9HSF4 SDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qlt A 1.15 BS01 J5W A 1 R144 A146 H158 N160 R162 V172 N174 W181 E184 S237 G238 R32 A34 H46 N48 R50 V60 N62 W69 E72 S125 G126 P17931 31246331 PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 6qno R 4.38 BS01 RET R 1 M86 A117 T118 E122 I189 Y191 V204 M207 F208 W265 Y268 A269 K296 M85 A116 T117 E121 I188 Y190 V203 M206 F207 W264 Y267 A268 K295 P02699 31251171 CGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIYVIAFLICWLPYAGVAFYIFTHQGSCFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEAST 6qto A 1.27 BS01 III B 1 I373 S375 V391 K422 S424 Y441 R465 W467 D484 K505 A506 N507 C509 A526 H528 K550 A551 S553 Y554 T568 K593 N594 F595 F646 I18 S20 V36 K64 S66 Y83 R107 W109 D126 K147 A148 N149 C151 A168 H170 K192 A193 S195 Y196 T210 K235 N236 F237 F288 2.3.2.27 P43254 MTFTRYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGSPDMDDAEEEAGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtq A 1.30 BS01 III B 1 V391 K422 Y441 W467 D484 C509 A551 S553 T568 K593 N594 F595 V34 K62 Y81 W107 D124 C149 A191 S193 T208 K233 N234 F235 2.3.2.27 P43254 TRYSRLRVIAEIRHNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtr A 1.37 BS01 III B 1 I373 S375 V391 S424 Y441 R465 W467 D484 K505 A506 N507 C509 A526 A551 S553 Y554 T568 K593 N594 F595 F646 S648 I19 S21 V37 S66 Y83 R107 W109 D126 K147 A148 N149 C151 A168 A193 S195 Y196 T210 K235 N236 F237 F278 S280 2.3.2.27 P43254 AMTFTRYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGAGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qts A 1.11 BS01 III B 1 I373 V391 K422 Y441 W467 D484 N507 C509 A526 A551 S553 T568 K593 N594 F595 I16 V34 K62 Y81 W107 D124 N147 C149 A166 A191 S193 T208 K233 N234 F235 2.3.2.27 P43254 TRYSRLRVIAEIRHNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtt A 1.51 BS01 III B 1 I373 S375 Y441 W467 D484 K505 A506 N507 C509 A526 D527 H528 K550 A551 S553 T568 K593 N594 F595 F646 S648 I19 S21 Y84 W110 D127 K148 A149 N150 C152 A169 D170 H171 K193 A194 S196 T211 K236 N237 F238 F278 S280 2.3.2.27 P43254 AMTFTRYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGSSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtu A 1.30 BS01 III B 1 I373 S375 V391 L423 S424 Y441 R465 W467 D484 C509 H528 K550 A551 S553 T568 K593 N594 F595 I19 S21 V37 L66 S67 Y84 R108 W110 D127 C152 H171 K193 A194 S196 T211 K236 N237 F238 2.3.2.27 P43254 AMTFTRYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtv A 1.31 BS01 III B 1 N372 I373 S375 V391 K422 Y441 W467 D484 A506 N507 C509 A526 D527 A551 S553 T568 K593 N594 F595 N14 I15 S17 V33 K61 Y80 W106 D123 A145 N146 C148 A165 D166 A190 S192 T207 K232 N233 F234 2.3.2.27 P43254 TRYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGSAGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtw A 1.39 BS01 III B 1 I373 S375 V391 K422 Y441 W467 D484 C509 A551 S553 T568 K593 N594 F595 I14 S16 V32 K60 Y79 W105 D122 C147 A189 S191 T206 K231 N232 F233 2.3.2.27 P43254 RYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEPQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qtx A 1.95 BS01 III B 1 I373 G390 V391 K422 L423 Y441 W467 D484 C509 A551 S553 T568 K593 N594 F595 I15 G32 V33 K60 L61 Y79 W105 D122 C147 A189 S191 T206 K231 N232 F233 2.3.2.27 P43254 TRYSRLRVIAEIRNIVSSIEFDRDDELFATAGVSRCIKVFDFSSVVNEQCPIVEMSTRSKLSCLSWNKHEKNHIASSDYEGIVTVWDVTTRQSLMEYEEHEKRAWSVDFSRTEPSMLVSGSDDCKVKVWCTRQEASVINIDMKANICCVKYNPGSSNYIAVGSADHHIHYYDLRNISQPLHVFSGHKKAVSYVKFLSNNELASASTDSTLRLWDVKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFEEEAGSYFISAVCWKSDSPTMLTANSQGTIKVLVLAA 6qua B 2.68 BS02 NUC F 1 G51 R52 N56 K73 R74 G46 R47 N51 K68 R69 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qua B 2.68 BS03 MN B 1 E47 N49 H50 E42 N44 H45 Q9HSF4 PDARSDARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALE 6qua C 2.68 BS02 NUC H 1 N49 G51 R52 N56 K73 R74 N39 G41 R42 N46 K63 R64 Q9HSF4 DARDLTAFQKNILTVLGEEARYGLAIKRELEEYYGEEVNHGRLYPNLDDLVNKGLVEKSELDKRTNEYALTNEGFDAVVDDLEWTLSKFVADADRRERVETIVADDAAALEH 6qyb A 1.18 BS08 CU1 A 8 C41 D61 C104 C117 C25 D45 C88 C101 Q9X8F4 31111982 GGVDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMAEHCRVCAEACRSCEQACQELLAGLG 6qyb A 1.18 BS12 CU1 A 12 C27 L90 C128 C11 L74 C112 Q9X8F4 31111982 GGVDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMAEHCRVCAEACRSCEQACQELLAGLG 6qyb A 1.18 BS15 CU1 A 15 C31 C68 T71 C93 C124 C128 C15 C52 T55 C77 C108 C112 Q9X8F4 31111982 GGVDREAMARCIEECLRCAQACTACADACLSEPTVADLTKCIRTDMDCADVCTATAAVLSRHTGYDANVTRAVLQACATVCAACGDECARHAGMAEHCRVCAEACRSCEQACQELLAGLG 6rar I 1.79 BS01 NUC B 1 T87 G88 H89 R120 G122 S124 K126 T127 H154 K157 Q227 M230 K231 R235 K236 D237 H336 G357 T358 G359 R360 N361 G366 A367 L381 S382 G384 T415 K416 S417 K418 S424 L425 F427 T83 G84 H85 R116 G118 S120 K122 T123 H150 K153 Q223 M226 K227 R231 K232 D233 H332 G353 T354 G355 R356 N357 G362 A363 L377 S378 G380 T411 K412 S413 K414 S420 L421 F423 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rar I 1.79 BS02 NUC C 1 T52 G54 V55 K56 I57 R84 G170 V171 R172 S186 R187 N188 K190 F226 M230 H234 F427 T48 G50 V51 K52 I53 R80 G166 V167 R168 S182 R183 N184 K186 F222 M226 H230 F423 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rar I 1.79 BS03 NUC D 1 P19 S20 R21 L22 K167 K340 K342 R360 S385 G386 F387 S388 D389 F427 R429 P15 S16 R17 L18 K163 K336 K338 R356 S381 G382 F383 S384 D385 F423 R425 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rar I 1.79 BS04 MN C 1 K167 D169 G170 E220 E319 K163 D165 G166 E216 E315 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rar I 1.79 BS05 AMP D 1 L147 E165 I166 K167 L168 R172 E220 F249 L290 M322 K324 W338 K340 L143 E161 I162 K163 L164 R168 E216 F245 L286 M318 K320 W334 K336 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6ras I 2.75 BS02 NUC C 1 T52 G54 V55 K56 I57 K167 G170 V171 R172 S186 R187 N188 K190 F226 M230 H234 E319 F427 T48 G50 V51 K52 I53 K163 G166 V167 R168 S182 R183 N184 K186 F222 M226 H230 E315 F423 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLACGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGFK 6ras I 2.75 BS04 AMP D 1 L147 A148 E165 I166 K167 L168 R172 E220 F249 L290 M322 K324 W338 K340 L143 A144 E161 I162 K163 L164 R168 E216 F245 L286 M318 K320 W334 K336 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLACGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGFK 6rau I 1.99 BS02 NUC C 1 P19 S20 R21 L22 T52 G54 V55 K56 I57 K167 G170 V171 R172 S186 R187 K190 F226 M230 H234 K340 K342 R360 S385 G386 F387 S388 D389 F427 R429 P15 S16 R17 L18 T48 G50 V51 K52 I53 K163 G166 V167 R168 S182 R183 K186 F222 M226 H230 K336 K338 R356 S381 G382 F383 S384 D385 F423 R425 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rce I 1.95 BS02 NUC C 1 T52 F53 G54 V55 K56 I57 R84 G170 V171 R172 S186 R187 N188 K190 F226 M230 H234 R426 F427 T48 F49 G50 V51 K52 I53 R80 G166 V167 R168 S182 R183 N184 K186 F222 M226 H230 R422 F423 A0A0A2ACP7 ELFKEEIIHQLELHPSRLDKEKIISEAMEDGIDDFFEGIRMALDPLVTFGVKIVPEKESEKSQNFLWEDFRKLANKLMQRELTGHAARDAILTAMESATKEEWNGFYRRVLIKDLRCGVSEKTINKIAKKFPKYAIPIFSCPLAHDSANHEKKMIGKKQIEIKLDGVRVLTIIRQNKVEMFSRNGKQFHNFGHIILEIENVLKEDPAPYDLVLDGEVMSANFQDLMKQVHRKDGKQTKDAVLHLFDLCPLENFQKGRWNTKQTARSLLVKKWVAKHSLLLKHIQTLEWENVDLDTIQGQKRFVELNKSAVEGGYEGVMIKDPDGMYECKRTHSWLKAKPFIEVTLKVVSVEEGTGRNKGRLGAILVEGEDDGYEYSLSCGSGFSDIQREEYWSKRKHLLGQLVEIRADAKTKSKDGVAFSLRFPRFKCFRGF 6rft A 2.30 BS01 ACO A 1 V25 F26 A82 V83 V85 R90 R91 R92 G93 L94 L95 T96 F117 S119 E120 I123 Y124 R126 V24 F25 A81 V82 V84 R89 R90 R91 G92 L93 L94 T95 F116 S118 E119 I122 Y123 R125 2.3.1.- 31254444 SELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rft B 2.30 BS01 ACO B 1 V25 F26 V83 V85 R90 R91 R92 G93 L95 T96 L116 F117 S119 E120 L122 I123 Y124 R126 V22 F23 V80 V82 R87 R88 R89 G90 L92 T93 L113 F114 S116 E117 L119 I120 Y121 R123 2.3.1.- 31254444 LTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rft B 2.30 BS02 ACO C 1 D266 L267 D257 L258 2.3.1.- 31254444 LTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rft C 2.30 BS01 ACO C 1 V25 F26 V83 V85 R90 R91 G93 L95 T96 L116 F117 S119 E120 I123 Y124 R126 V24 F25 V82 V84 R89 R90 G92 L94 T95 L115 F116 S118 E119 I122 Y123 R125 2.3.1.- 31254444 SELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rft D 2.30 BS01 ACO D 1 V25 V83 V85 R90 R91 R92 G93 L95 T96 E120 L122 I123 R126 V23 V81 V83 R88 R89 R90 G91 L93 T94 E118 L120 I121 R124 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rft E 2.30 BS02 ACO E 1 V25 V83 V85 R91 R92 G93 L95 T96 E120 L122 I123 R126 V24 V82 V84 R90 R91 G92 L94 T95 E119 L121 I122 R125 2.3.1.- 31254444 SELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rft F 2.30 BS02 ACO F 1 V25 F26 V83 V85 R90 R91 R92 G93 L95 T96 L122 I123 Y124 R126 V23 F24 V81 V83 R88 R89 R90 G91 L93 T94 L120 I121 Y122 R124 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx D 1.90 BS01 P4K D 1 M19 Y23 F26 M17 Y21 F24 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx D 1.90 BS02 P4K A 1 Q279 G371 S374 A396 Q269 G361 S364 A386 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx A 1.90 BS01 P4K A 2 M19 Y23 F26 D410 F411 M17 Y21 F24 D403 F404 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGAGPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx A 1.90 BS02 P4K A 1 Q279 S374 A396 W401 Q272 S367 A389 W394 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGAGPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx B 1.90 BS01 P4K B 1 M19 A22 Y23 F26 A82 D410 M17 A20 Y21 F24 A80 D403 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx B 1.90 BS02 P4K B 2 Q279 G371 V373 S374 W401 P402 Q272 G364 V366 S367 W394 P395 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx C 1.90 BS01 P4K B 3 Q279 G371 S374 A396 G400 Q271 G363 S366 A388 G392 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGGPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx C 1.90 BS02 P4K C 1 A22 Y23 F26 T84 D410 A20 Y21 F24 T82 D402 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGGPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rfx E 1.90 BS01 P4K E 1 M19 A22 Y23 F26 A82 T84 M17 A20 Y21 F24 A80 T82 2.3.1.- 31254444 ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGPNAELHVQEVLGTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAPDDF 6rgi A 2.64 BS01 HEC A 1 R13 C14 C17 H18 V28 G29 P30 L32 I35 R38 W59 M64 Y67 L68 K72 Y74 M80 A81 F82 L94 R17 C18 C21 H22 V32 G33 P34 L36 I39 R42 W48 M53 Y56 L57 K61 Y63 M69 A70 F71 L83 P00044 31254353 EFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLKKATE 6rgi A 2.64 BS02 FWQ A 1 R13 K73 G77 A81 F82 G83 K86 R17 K62 G66 A70 F71 G72 K75 P00044 31254353 EFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLKKATE 6rgi A 2.64 BS03 IMD A 1 Y67 L68 Y74 F82 Y56 L57 Y63 F71 P00044 31254353 EFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLKKATE 6rq7 B 2.69 BS01 DO3 B 1 N295 N297 N247 N249 P43652 STQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLEGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSELQRKTDRFLVNLVKLKHELTDEELQ 6rq7 B 2.69 BS02 DO3 B 2 Y198 I221 I294 I346 N452 Y150 I173 I246 I295 N401 P43652 STQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLEGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSELQRKTDRFLVNLVKLKHELTDEELQ 6rq7 B 2.69 BS03 DO3 B 3 D358 F484 D307 F433 P43652 STQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLEGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSELQRKTDRFLVNLVKLKHELTDEELQ 6rza A 5.40 BS01 GTP A 1 G10 Q11 A12 Q15 E71 A99 A100 N101 S140 G143 G144 T145 I171 T179 N206 Y224 L227 N228 G10 Q11 A12 Q15 E60 A88 A89 N90 S129 G132 G133 T134 I160 T168 N195 Y213 L216 N217 Q2XVP4 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 6rza B 5.40 BS01 GDP B 1 G10 Q11 C12 Q15 N99 G141 G142 T143 D177 E181 N204 Y222 N226 G10 Q11 C12 Q15 N99 G141 G142 T143 D177 E181 N204 Y222 N226 P02554 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 6rza B 5.40 BS02 TA1 B 1 E22 V23 D26 D224 H227 L228 A231 F270 P272 T274 R276 R318 P358 R359 G360 L361 E22 V23 D26 D224 H227 L228 A231 F270 P272 T274 R276 R318 P358 R359 G360 L361 P02554 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ