5z3l A 4.31 BS01 NUC I 1 R40 Y41 G44 T45 V46 A47 R49 K56 R63 K64 L65 R69 R4 Y5 G8 T9 V10 A11 R13 K20 R27 K28 L29 R33 P84233 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3l A 4.31 BS02 NUC J 1 R40 R42 P43 T45 R63 R72 R83 F84 R116 V117 R4 R6 P7 T9 R27 R36 R47 F48 R80 V81 P84233 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3l B 4.31 BS02 NUC J 1 T30 K31 P32 R36 T16 K17 P18 R22 P62799 30867599 AKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 5z3l C 4.31 BS01 NUC I 1 A14 R29 R42 V43 K75 T76 R77 A3 R18 R31 V32 K64 T65 R66 Q6AZJ8 30867599 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 5z3l C 4.31 BS02 NUC J 1 A12 K13 A14 K15 R17 R20 G28 R32 R77 A1 K2 A3 K4 R6 R9 G17 R21 R66 Q6AZJ8 30867599 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 5z3l D 4.31 BS01 NUC I 1 T29 K31 S33 I36 Y37 T85 T1 K3 S5 I8 Y9 T57 P02281 30867599 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5z3l D 4.31 BS02 NUC J 1 R30 Y39 I51 S53 R83 S84 R2 Y11 I23 S25 R55 S56 P02281 30867599 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5z3l E 4.31 BS01 NUC I 1 R40 Y41 R42 P43 T45 R63 R72 L82 R83 F84 Q85 R116 T118 R1 Y2 R3 P4 T6 R24 R33 L43 R44 F45 Q46 R77 T79 P84233 30867599 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3l E 4.31 BS02 NUC J 1 Y41 V46 R63 K64 L65 P66 R69 Y2 V7 R24 K25 L26 P27 R30 P84233 30867599 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3l F 4.31 BS01 NUC I 1 R17 H18 T30 K31 P32 A33 R36 R1 H2 T14 K15 P16 A17 R20 P62799 30867599 RHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 5z3l O 4.31 BS01 NUC I 1 R898 K900 N901 S904 K905 L906 N929 Q1051 W1185 N1186 R1224 R177 K179 N180 S183 K184 L185 N208 Q310 W444 N445 R483 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 5z3l O 4.31 BS02 NUC J 1 L825 S826 P851 E874 Y875 K878 F1048 N1049 I1052 K1057 M1112 T1113 Q1114 G1135 R1142 R1164 A1165 G1166 L104 S105 P130 E153 Y154 K157 F307 N308 I311 K316 M371 T372 Q373 G394 R401 R423 A424 G425 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 5z3o A 3.62 BS01 NUC I 1 R40 Y41 P43 G44 V46 R49 K56 R63 K64 L65 P66 R69 R83 R4 Y5 P7 G8 V10 R13 K20 R27 K28 L29 P30 R33 R47 P84233 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3o A 3.62 BS02 NUC J 1 R40 Y41 R42 T45 R72 R83 F84 S86 R116 V117 T118 R4 Y5 R6 T9 R36 R47 F48 S50 R80 V81 T82 P84233 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3o C 3.62 BS01 NUC I 1 R29 R35 R42 V43 A45 K75 T76 R18 R24 R31 V32 A34 K64 T65 Q6AZJ8 30867599 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 5z3o D 3.62 BS02 NUC J 1 T29 Y39 I51 S52 S53 R83 S84 T85 T1 Y11 I23 S24 S25 R55 S56 T57 P02281 30867599 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5z3o E 3.62 BS02 NUC J 1 R40 Y41 G44 V46 K56 R63 K64 L65 P66 R69 R1 Y2 G5 V7 K17 R24 K25 L26 P27 R30 P84233 30867599 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3o O 3.62 BS01 NUC I 1 R898 N901 S904 K905 N929 Q1051 I1052 R1164 W1185 N1186 R1224 R177 N180 S183 K184 N208 Q310 I311 R423 W444 N445 R483 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 5z3o O 3.62 BS02 NUC J 1 L825 S826 R854 E874 Y875 K878 F1048 N1049 M1053 K1057 M1112 T1113 Q1114 G1135 R1142 R1164 G1166 L104 S105 R133 E153 Y154 K157 F307 N308 M312 K316 M371 T372 Q373 G394 R401 R423 G425 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 5z3o O 3.62 BS03 ADP O 1 T766 L767 K768 Q771 M794 G795 L796 G797 K798 T799 I800 T45 L46 K47 Q50 M73 G74 L75 G76 K77 T78 I79 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 5z3o O 3.62 BS04 MG O 1 G797 K798 T799 G76 K77 T78 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 5z3t O 4.06 BS01 NUC I 1 M899 K900 N901 S904 K905 L906 R1164 W1185 M178 K179 N180 S183 K184 L185 R423 W444 3.6.4.- P22082 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREEELKDSEINEILARNDEEMAVLTRMDEDRSKKEKREESESAAVYNGR 5z3t O 4.06 BS02 NUC J 1 L825 R854 E874 Y875 K878 F1048 M1112 T1113 Q1114 G1135 R1142 S1162 A1165 L104 R133 E153 Y154 K157 F307 M371 T372 Q373 G394 R401 S421 A424 3.6.4.- P22082 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREEELKDSEINEILARNDEEMAVLTRMDEDRSKKEKREESESAAVYNGR 5z3t O 4.06 BS03 MG O 1 D894 L1168 D173 L427 3.6.4.- P22082 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREEELKDSEINEILARNDEEMAVLTRMDEDRSKKEKREESESAAVYNGR 5z3t O 4.06 BS04 ADP O 1 T766 K768 Y770 G795 L796 G797 K798 I800 N1171 Q1173 I1200 T45 K47 Y49 G74 L75 G76 K77 I79 N430 Q432 I459 3.6.4.- P22082 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREEELKDSEINEILARNDEEMAVLTRMDEDRSKKEKREESESAAVYNGR 5z3t O 4.06 BS05 BEF O 1 L1168 L1170 R1199 L427 L429 R458 3.6.4.- P22082 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKREEELKDSEINEILARNDEEMAVLTRMDEDRSKKEKREESESAAVYNGR 5z3t A 4.06 BS02 NUC J 1 H39 R40 Y41 R42 T45 R63 R72 R83 F84 Q85 R116 V117 T118 M120 H3 R4 Y5 R6 T9 R27 R36 R47 F48 Q49 R80 V81 T82 M84 P84233 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3t C 4.06 BS02 NUC J 1 K13 K15 T16 R17 R29 R32 K2 K4 T5 R6 R18 R21 Q6AZJ8 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 5z3t D 4.06 BS01 NUC I 1 R30 K31 E32 I36 Y37 R2 K3 E4 I8 Y9 P02281 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5z3t D 4.06 BS02 NUC J 1 T29 R30 Y39 S52 S53 S84 T1 R2 Y11 S24 S25 S56 P02281 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5z3t E 4.06 BS02 NUC J 1 R40 Y41 P43 G44 T45 V46 A47 R63 K64 L65 P66 R69 R83 R1 Y2 P4 G5 T6 V7 A8 R24 K25 L26 P27 R30 R44 P84233 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5z3t G 4.06 BS01 NUC I 1 A12 R17 R32 R42 R77 A1 R6 R21 R31 R66 Q6AZJ8 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 5zgc A 2.90 BS01 III G 1 E177 F180 Q228 I230 H248 V292 F293 F294 G295 E296 L298 L322 E323 V324 E325 P326 S329 A333 W353 E46 F49 Q97 I99 H117 V161 F162 F163 G164 E165 L167 L191 E192 V193 E194 P195 S198 A202 W222 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5zgc B 2.90 BS01 III H 1 E177 F180 Q228 I230 H248 V292 F293 F294 G295 E296 H305 L322 E323 V324 E325 P326 S329 G349 P350 W353 E42 F45 Q93 I95 H113 V157 F158 F159 G160 E161 H170 L187 E188 V189 E190 P191 S194 G214 P215 W218 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGK 5zgc C 2.90 BS01 III I 1 E177 F180 Q228 I230 H248 V292 F293 F294 G295 E296 L322 E323 V324 E325 P326 W353 E45 F48 Q96 I98 H116 V160 F161 F162 G163 E164 L190 E191 V192 E193 P194 W221 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5zgc D 2.90 BS01 III K 1 F180 Q228 I230 H248 V292 F293 F294 G295 E296 E323 E325 P326 W353 F46 Q94 I96 H114 V158 F159 F160 G161 E162 E189 E191 P192 W219 3.5.1.- Q9NTG7 SLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5zgc E 2.90 BS01 III J 1 E177 F180 E181 Q228 I230 H248 V292 F293 F294 G295 E296 V324 E325 E56 F59 E60 Q107 I109 H127 V171 F172 F173 G174 E175 V203 E204 3.5.1.- Q9NTG7 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5zgc F 2.90 BS01 III L 1 F294 G295 E296 E323 V324 E325 P326 F112 G113 E114 E141 V142 E143 P144 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFDIRADVMADPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5zgn A 2.24 BS01 NUC G 1 L4 K5 R12 T31 I32 T33 L2 K3 R10 T29 I30 T31 A0A0H3GLZ1 ALKKQRIDLRLTDDDKSIIEEAAAISNQTITQFVVASASERAAEVIEQHRRMVLNEQSWSLVMEAITQP 5zgn A 2.24 BS02 NUC H 1 R8 D10 R6 D8 A0A0H3GLZ1 ALKKQRIDLRLTDDDKSIIEEAAAISNQTITQFVVASASERAAEVIEQHRRMVLNEQSWSLVMEAITQP 5zgn B 2.24 BS01 NUC G 1 R8 D10 R12 R4 D6 R8 A0A0H3GLZ1 KKQRIDLRLTDDDKSIIEEAAAISNQTITQFVVASASERAAEVIEQHRRMVLNEQSWSLVMEAITQPPAPNDRLKRAAKRLQ 5zgn B 2.24 BS02 NUC H 1 R12 K18 T31 I32 T33 R8 K14 T27 I28 T29 A0A0H3GLZ1 KKQRIDLRLTDDDKSIIEEAAAISNQTITQFVVASASERAAEVIEQHRRMVLNEQSWSLVMEAITQPPAPNDRLKRAAKRLQ 5zgn E 2.24 BS01 NUC G 1 R12 K18 E22 T31 I32 T33 R8 K14 E18 T27 I28 T29 A0A0H3GLZ1 KKQRIDLRLTDDDKSIIEEAAAISNQTITQFVVASASERAAEVIEQHRRMVLNEQSWSLVMEAITQPPAPNDRLKRAAKRLQ 5zjw A 1.80 BS01 9EO A 1 I327 G328 E329 G330 T332 G333 I334 V335 A348 K350 M352 M395 E396 F397 L398 G401 D444 L447 D458 I29 G30 E31 G32 T34 G35 I36 V37 A50 K52 M54 M97 E98 F99 L100 G103 D146 L149 D160 2.7.11.1 O96013 SSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 5zjw A 1.80 BS02 BCT A 1 K345 Y382 K47 Y84 2.7.11.1 O96013 SSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 5zki A 2.32 BS01 NUC C 1 R109 K110 V132 S137 R138 G139 A140 A144 G145 F168 N171 S172 N176 M180 R183 Y310 R314 R52 K53 V75 S80 R81 G82 A83 A87 G88 F111 N114 S115 N119 M123 R126 Y253 R257 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAK 5zki A 2.32 BS02 NUC D 1 K113 S172 N176 L311 K315 R320 R324 K56 S115 N119 L254 K258 R263 R267 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAK 5zki B 2.32 BS01 NUC E 1 R109 K110 S137 R138 G139 A140 A144 G145 F168 N171 S172 N176 M180 Y310 L311 R314 R53 K54 S81 R82 G83 A84 A88 G89 F112 N115 S116 N120 M124 Y254 L255 R258 3.1.30.- Q9Y2C4 AEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 5zkj A 2.80 BS01 NUC E 1 R109 K110 F114 S137 R138 G139 A140 A144 G145 K148 F168 N171 S172 N176 M180 R183 Y310 L311 R314 R54 K55 F59 S82 R83 G84 A85 A89 G90 K93 F113 N116 S117 N121 M125 R128 Y255 L256 R259 3.1.30.- Q9Y2C4 SAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLE 5zkj A 2.80 BS02 NUC F 1 H111 K115 S172 N176 L311 K315 R320 R324 K327 H56 K60 S117 N121 L256 K260 R265 R269 K272 3.1.30.- Q9Y2C4 SAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLE 5zkj B 2.80 BS02 NUC D 1 K115 S172 N176 L311 K315 R320 R324 K327 K60 S117 N121 L256 K260 R265 R269 K272 3.1.30.- Q9Y2C4 SAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKE 5zmw A 2.50 BS01 DMU A 1 E412 T415 F455 L478 M479 R505 K511 R529 T532 T533 R534 D568 E418 T421 F461 L484 M485 R511 K517 R535 T538 T539 R540 D574 3.6.3.8 P04191 30482857 SDNAIAMEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPQGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 5zmw A 2.50 BS02 DMU A 2 L96 I99 W107 A313 L797 G801 L102 I105 W113 A319 L803 G807 3.6.3.8 P04191 30482857 SDNAIAMEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPQGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 5zqo A 2.06 BS02 9GX A 1 H1031 G1032 S1033 P1034 F1035 A1049 Y1050 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 H80 G81 S82 P83 F84 A98 Y99 Y109 F110 A111 K116 S117 Y120 I124 2.4.2.30 Q9H2K2 30883102 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5zqp A 1.99 BS02 9H3 A 1 H1031 G1032 S1033 P1034 F1035 R1047 A1049 Y1050 Y1060 A1062 K1067 S1068 Y1071 G1074 I1075 H80 G81 S82 P83 F84 R96 A98 Y99 Y109 A111 K116 S117 Y120 G123 I124 2.4.2.30 Q9H2K2 30883102 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5zqq A 2.29 BS02 9H6 A 1 H1031 G1032 P1034 F1035 H1048 A1049 Y1050 Y1060 A1062 S1068 Y1071 G1074 I1075 H80 G81 P83 F84 H97 A98 Y99 Y109 A111 S117 Y120 G123 I124 2.4.2.30 Q9H2K2 30883102 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5zqr A 1.75 BS02 9H9 A 1 H1031 G1032 S1033 P1034 F1035 H1048 Y1050 Y1060 F1061 A1062 K1067 S1068 Y1071 G1074 I1075 H80 G81 S82 P83 F84 H97 Y99 Y109 F110 A111 K116 S117 Y120 G123 I124 2.4.2.30 Q9H2K2 30883102 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5zxi A 2.10 BS01 9LU A 1 V245 C249 T252 T253 H287 I290 L294 L303 V305 I328 K331 H413 M417 L433 Y437 V60 C64 T67 T68 H102 I105 L109 L118 V120 I143 K146 H228 M232 L248 Y252 Q03181 30258544 QVADLKAFSKHIYNAYLKNFNMTKKKARSILTGPFVIHDIETLWQAEKGLVWYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYK 5zxi B 2.10 BS01 9LU B 1 L219 V245 F246 R248 C249 T252 T253 H287 I290 L294 L303 V305 V312 I327 I328 K331 H413 L433 Y437 L37 V50 F51 R53 C54 T57 T58 H92 I95 L99 L108 V110 V117 I132 I133 K136 H218 L238 Y242 Q03181 30258544 KAFSKHIYNAYLKNFNMTKKKARSILTPFVIHDIETLWQAEKYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYK 5zxk A 1.96 BS01 H6P A 1 H351 Y352 W391 R412 R418 R469 L471 H55 Y56 W95 R116 R122 R173 L175 O00481 GAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICP 5zxu A 2.20 BS01 NDP A 1 P50 M130 T134 A155 G158 A159 V160 A179 G180 K184 H200 N223 V224 C245 G246 I248 S249 Y251 F280 I281 I282 L326 L327 G329 N331 P45 M125 T129 A150 G153 A154 V155 A174 G175 K179 H195 N218 V219 C240 G241 I243 S244 Y246 F275 I276 I277 L321 L322 G324 N326 30251539 ARQIVLASRPVGAPTAENFALTQSDIPTPAQGEMLLRSVYLSLDPYMRGRMSDAKSYAEPVGIDEVMVGGTVCQVEASNHAEFEVGEWVLAYTGWQDYAISDGEGLIKLGKQPSHPSYALGVMGMPGFTAYMGLLDIGQPKEGDTLVVAAATGAVGSMVGQIGKLKGCRVIGIAGGEEKCQFAKDTLGFDECIDHKAADFAEQLAKVCHNGIDIYFENVGGKVFDAVMPLLNTGARIPLCGLISQYNATSLPEGPDRMSMLMAQLLIKRIKMQGFIIFDDYGHRYGEFAADMTQWLAQGKIHYREHLVQGLENAPDAFIGLLEGKNFGKMVVQTNQP 6a71 B 1.60 BS01 9UX B 1 G11 T13 C14 C17 G10 T12 C13 C16 B7ZLR3 30643139 CSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPAVISPEELRAAIEDMGFEASVVS 6byr A 3.66 BS01 ATP A 1 G105 G107 S108 F109 V112 A125 K127 M175 V178 E182 K223 E225 N226 L228 T238 D239 F382 G105 G107 S108 F109 V112 A125 K127 M175 V178 E182 K223 E225 N226 L228 T238 D239 F382 2.7.11.11 P17612 30905674 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6byr A 3.66 BS02 MG A 1 D221 D239 D221 D239 2.7.11.11 P17612 30905674 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6byr A 3.66 BS03 MG A 2 N226 D239 N226 D239 2.7.11.11 P17612 30905674 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6byz A 2.96 BS02 J18 A 1 A198 L201 F202 E205 Y302 Y314 T316 V360 G361 Q363 K364 I374 N376 R477 A479 A156 L159 F160 E163 Y260 Y272 T274 V318 G319 Q321 K322 I332 N334 R435 A437 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6byz B 2.96 BS02 J18 B 1 A198 L201 F202 L204 E205 T208 Y302 Y314 T316 V360 G361 Q363 K364 I374 N376 R477 A479 A155 L158 F159 L161 E162 T165 Y259 Y271 T273 V317 G318 Q320 K321 I331 N333 R434 A436 3.4.24.56 P14735 NPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6cw6 A 2.85 BS02 PBS A 1 Y73 S76 D80 I81 L84 V118 F120 W133 L150 D153 G155 T156 V160 Y67 S70 D74 I75 L78 V112 F114 W127 L144 D147 G149 T150 V154 P11609 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 6cw9 A 2.00 BS02 7LM A 1 Y73 S76 D80 L84 F120 W133 W142 P146 D153 G155 T156 V160 Y68 S71 D75 L79 F115 W128 W137 P141 D148 G150 T151 V155 A0A0R4J090 KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSAHGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 6cwb A 2.85 BS02 FJJ A 1 Y73 S76 F77 D80 L84 L100 F120 W133 L150 D153 G155 T156 V160 L163 Y67 S70 F71 D74 L78 L94 F114 W127 L144 D147 G149 T150 V154 L157 A0A0R4J090 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 6cwe A 2.20 BS02 7LP A 1 Y73 S76 F77 D80 I81 L84 F120 W133 W142 D153 G155 T156 V160 Y67 S70 F71 D74 I75 L78 F114 W127 W136 D147 G149 T150 V154 A0A0R4J090 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 6d00 1 4.00 BS01 ADP 1 1 V179 G208 G210 K211 T212 A213 I345 P383 D384 V157 G186 G188 K189 T190 A191 I315 P353 D354 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 1 4.00 BS02 ADP 1 2 T608 G611 T613 L614 D678 I775 R779 A815 R816 T578 G581 T583 L584 D635 I716 R720 A756 R757 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 2 4.00 BS01 ADP 2 1 V179 I180 R182 P207 G208 G210 K211 T212 A213 I345 L349 D384 V157 I158 R160 P185 G186 G188 K189 T190 A191 I315 L319 D354 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 2 4.00 BS02 ADP 2 2 V571 V572 T608 G609 K612 T613 L614 I775 R779 R816 V541 V542 T578 G579 K582 T583 L584 I716 R720 R757 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 3 4.00 BS01 ADP 3 1 V179 I180 R182 G210 K211 T212 A213 I345 L349 D384 V157 I158 R160 G188 K189 T190 A191 I315 L319 D354 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 3 4.00 BS02 ADP 3 2 V572 T608 G609 C610 G611 K612 T613 L614 I775 R779 R816 V542 T578 G579 C580 G581 K582 T583 L584 I716 R720 R757 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 4 4.00 BS01 ADP 4 1 V179 R182 G210 K211 T212 A213 I345 L349 R380 P383 D384 I387 V157 R160 G188 K189 T190 A191 I315 L319 R350 P353 D354 I357 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 4 4.00 BS02 ADP 4 2 V572 T608 G609 C610 G611 K612 T613 L614 R779 A815 R816 N819 V542 T578 G579 C580 G581 K582 T583 L584 R720 A756 R757 N760 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 4 4.00 BS03 ADP 5 1 E753 R757 E694 R698 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 5 4.00 BS01 ADP 5 2 G210 K211 T212 A213 E216 L349 P383 G188 K189 T190 A191 E194 L319 P353 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 5 4.00 BS02 ADP 5 1 V572 T608 G609 K612 T613 L614 I775 R779 A815 R816 V542 T578 G579 K582 T583 L584 I716 R720 A756 R757 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d00 6 4.00 BS01 ADP 6 1 P178 V179 I180 G208 G210 K211 T212 A213 I345 L349 P383 D384 P156 V157 I158 G186 G188 K189 T190 A191 I315 L319 P353 D354 30595457 SSMQFTDKATETLNAAAKYAAENSHVQLHPSHVAVVMLDEENSLFRSILEKAGGDVVSIERGFKKIMVRQPHSPELAKLLHYAHEHMKKQRDLYIAQDHLILALADLPSMAQVLKEGGVTKKSLENAVTHVRGAYEALSKYCIDLTELAASGKLDPVIGRDEIISRVIRVLSRRTKNNPCLVGEPGVGKTAIAEGLANRIVKGDIPSSLQKKVYSLDIGSLLAGAGEFEERLKAVLKELKEAQAIVFIDEIHTVLGAAIDAANLLKPMLARGELRCIGATTLTEYRQYVEKDPAFERRFQLVMVEEPSVTDTISILRGLKERYETHHGVRIADAAIVAAAQLAARYITQRFMPDKAIDLIDEACANTRVQLDSQPEAIDKLERRHLQLEVEATALEKEKDAASKQRLQEVRAEMARIQEELRPLKMKYESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVGQDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLCVKELAAFLFNDPGAIVRIDMSEYMEKHAVSRLGQLTEAVRRRPYTVVLFDEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSNLTKNAVLATARRHFANEFINRIDELIVFNRLTPSNIRKIVDVRLKEVQERLDEKQITLDVDDKAKDLLAQQGFDPVYGARPLNRLIQHALLTQLSRLLLDGGVRPGEIAKVTVDQEGEIIVIRNHGI 6d78 A 2.35 BS01 III C 1 Y7 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 A150 V152 Q155 L156 Y159 Y7 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 A150 V152 Q155 L156 Y159 P01892 30617019 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 6d78 D 2.35 BS01 III C 1 Q30 Y50 Q30 Y50 K7N5M3 30617019 KEVEQNSGPLSVPEGAIASLNCTYSYRGSQSFFWYRQYSGKSPELIMFIYSNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAVNFGGGKLIFGQGTELSVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANIPEDTFFPS 6d78 E 2.35 BS01 III C 1 N33 W98 S99 F100 G101 N28 W93 S94 F95 G96 K7N5M4 30617019 GITQAPTSQILAAGRRMTLRCTQDMRHNAMYWYRQDLGLGLRLIHYSNTAGTTGKGEVPDGYSVSRANTDDFPLTLASAVPSQTSVYFCASSWSFGTEAFFGQGTRLTVVEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 6da2 A 2.65 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 F302 A305 G306 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 A448 M452 R78 I91 S92 W99 R103 F110 F260 A263 G264 I327 A328 L331 R333 P392 F393 G394 S395 R398 N399 C400 I401 G402 A406 M410 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6da2 A 2.65 BS02 G0D A 1 R105 R106 F108 S119 I120 F215 F241 I301 F304 A305 T309 A370 E374 R78 R79 F81 S92 I93 F184 F210 I259 F262 A263 T267 A328 E332 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6da3 A 2.37 BS02 G0D A 1 F108 S119 F241 I301 F304 A305 T309 F82 S93 F207 I255 F258 A259 T263 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNPQDPFVENTKKLPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6da8 A 2.80 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 I301 F302 A305 G306 T309 V313 I369 A370 L373 R375 P434 F435 G436 R440 N441 C442 I443 G444 A448 M452 R79 I92 S93 W100 R104 F111 I256 F257 A260 G261 T264 V268 I324 A325 L328 R330 P389 F390 G391 R395 N396 C397 I398 G399 A403 M407 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6da8 A 2.80 BS02 G0J A 1 R105 F108 S119 F220 F241 I301 A305 T309 R79 F82 S93 F187 F208 I256 A260 T264 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6daa A 2.15 BS02 G0M A 1 S119 F220 F241 F304 A305 T309 S93 F187 F208 F259 A260 T264 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6dab A 2.35 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 F302 A305 G306 T309 V313 L364 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 F447 A448 M452 R77 I90 S91 W98 R102 F109 F242 A245 G246 T249 V253 L304 I309 A310 L313 R315 P374 F375 G376 S377 R380 N381 C382 I383 G384 F387 A388 M392 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNQDPFDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESDFLQLMIDSQNKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6dab A 2.35 BS02 G0V A 1 F108 S119 F241 F304 A305 T309 A370 F80 S91 F198 F244 A245 T249 A310 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 SHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNQDPFDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESDFLQLMIDSQNKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6dac A 2.55 BS02 FZV A 1 S119 F215 F241 I301 F304 A305 T309 A370 M371 S93 F186 F212 I261 F264 A265 T269 A330 M331 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDVDFLQLMIDSQNSKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6dag A 2.80 BS01 HEM A 1 R105 I118 S119 W126 R130 F302 A305 G306 T309 I369 A370 L373 R375 P434 F435 G436 S437 R440 N441 C442 I443 G444 A448 R79 I92 S93 W100 R104 F257 A260 G261 T264 I324 A325 L328 R330 P389 F390 G391 S392 R395 N396 C397 I398 G399 A403 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6dag A 2.80 BS02 G0Y A 1 R105 R106 F108 S119 I120 F241 I301 F304 A305 T309 R79 R80 F82 S93 I94 F208 I256 F259 A260 T264 1.14.14.-,1.14.14.56,1.14.14.55 P08684 30912932 THSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 6dfl A 2.40 BS01 G9S B 1 I166 Y211 I217 L219 R221 L225 F227 L228 L247 M250 E251 I148 Y193 I199 L201 R203 L207 F209 L210 L229 M232 E233 2.7.1.-,2.7.10.2 Q9HUF7 MRLVLEEPFKRLWNGRDPFEAVEALQGKVYRELEGRRTLRTEVDGRGYFVKIHRLGARQEWQAIRRLHEAGVATMTAVAYGERGSDPARQHSFIVTEELAPTVDLEVFSQDWRERPPPPRLKRALVEAVARMVGDMHRAGVNHRDCYICHFLLHTDKPVSADDFRLSVIDLHRAQTRDATPKRWRNKDLAALYFSALDIGLTRRDKLRFLRTYFRRPLREILRDEAGLLAWMERKAEKLYE 6dht A 1.42 BS01 CA A 1 D349 H351 D354 E355 G390 D323 H325 D328 E329 G364 3.2.1.151 A7LXT3 30668971 IPNDAIRLNQLGYYPNQEKIAVVDSGKVEEFVIWDAVSGEQVFVGKSLYTAKSAWSDKTRTTLDFSAVTTPGKYILKVNGASVTFLIKDSVLSPLADAALKSFYYQRTAMPIEEQYAGQWHRMAGHPDNHVLIHPSAASPDRPAGTIVSSSKGWYDAGDYNKYIVNSGYSIGLMQSIYQLFLDYFSRQKINIPESNNHTPDLLDEMQFNLDWMLTMQDPEDGGVYHKLTTPFFEGFVKPVDCKQQRYVVQKSVTAALDFAAVMAQSSRLFASYEEDYPGFSKRALLAAEKAYAWAEKHPEAYYNQNLLNQKYQPAIATGEYGDTHADDEFFWAASELYFSTGKEIYREEAIKKAPQIYTAPGWGNTFALGIFAWLQPGRELNEADRRFADSLKTELLKYADKVIEGAEQTPFHAPYGNDAKDFFWGCLAEKCMNQGVSLMYAYLQTGKDVYLTNAYRNMDYILGRNATGFCYVTGLGTKSPKHPHHRLSASDDIEDPIPGFLVGGPNPASPDESYVDTEDSYASNEVAINWNAALVALASSLDALAV 6dht A 1.42 BS02 CA A 2 E220 S221 N223 T225 P226 D227 D230 E194 S195 N197 T199 P200 D201 D204 3.2.1.151 A7LXT3 30668971 IPNDAIRLNQLGYYPNQEKIAVVDSGKVEEFVIWDAVSGEQVFVGKSLYTAKSAWSDKTRTTLDFSAVTTPGKYILKVNGASVTFLIKDSVLSPLADAALKSFYYQRTAMPIEEQYAGQWHRMAGHPDNHVLIHPSAASPDRPAGTIVSSSKGWYDAGDYNKYIVNSGYSIGLMQSIYQLFLDYFSRQKINIPESNNHTPDLLDEMQFNLDWMLTMQDPEDGGVYHKLTTPFFEGFVKPVDCKQQRYVVQKSVTAALDFAAVMAQSSRLFASYEEDYPGFSKRALLAAEKAYAWAEKHPEAYYNQNLLNQKYQPAIATGEYGDTHADDEFFWAASELYFSTGKEIYREEAIKKAPQIYTAPGWGNTFALGIFAWLQPGRELNEADRRFADSLKTELLKYADKVIEGAEQTPFHAPYGNDAKDFFWGCLAEKCMNQGVSLMYAYLQTGKDVYLTNAYRNMDYILGRNATGFCYVTGLGTKSPKHPHHRLSASDDIEDPIPGFLVGGPNPASPDESYVDTEDSYASNEVAINWNAALVALASSLDALAV 6dht A 1.42 BS03 MG A 1 S515 D518 I520 S489 D492 I494 3.2.1.151 A7LXT3 30668971 IPNDAIRLNQLGYYPNQEKIAVVDSGKVEEFVIWDAVSGEQVFVGKSLYTAKSAWSDKTRTTLDFSAVTTPGKYILKVNGASVTFLIKDSVLSPLADAALKSFYYQRTAMPIEEQYAGQWHRMAGHPDNHVLIHPSAASPDRPAGTIVSSSKGWYDAGDYNKYIVNSGYSIGLMQSIYQLFLDYFSRQKINIPESNNHTPDLLDEMQFNLDWMLTMQDPEDGGVYHKLTTPFFEGFVKPVDCKQQRYVVQKSVTAALDFAAVMAQSSRLFASYEEDYPGFSKRALLAAEKAYAWAEKHPEAYYNQNLLNQKYQPAIATGEYGDTHADDEFFWAASELYFSTGKEIYREEAIKKAPQIYTAPGWGNTFALGIFAWLQPGRELNEADRRFADSLKTELLKYADKVIEGAEQTPFHAPYGNDAKDFFWGCLAEKCMNQGVSLMYAYLQTGKDVYLTNAYRNMDYILGRNATGFCYVTGLGTKSPKHPHHRLSASDDIEDPIPGFLVGGPNPASPDESYVDTEDSYASNEVAINWNAALVALASSLDALAV 6dtn B 1.48 BS01 III A 1 W20 M30 L31 G32 Y34 I37 G69 A70 G71 R74 I75 D91 I92 T93 F96 C117 G118 L119 Q120 Q135 W136 V137 H140 N168 Q171 D177 D180 S182 D212 E213 I214 Y215 W30 M40 L41 G42 Y44 I47 G79 A80 G81 R84 I85 D101 I102 T103 F106 C127 G128 L129 Q130 Q145 W146 V147 H150 N178 Q181 D187 D190 S192 D222 E223 I224 Y225 2.1.1.244 Q9BV86 30883119 HHSSGLVPRGSTSEVIEDEKQFYSKAKTYWKQIPPTVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSCALDCGAGIGRITKRLLLPLFREVDMVDITEDFLVQAKTYLGEEGKRVRNYFCCGLQDFTPEPDSYDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVIKDNMAQEGVILDDVDSSVCRDLDVVRRIICSAGLSLLAEERQENLPDEIYHVYSFALR 6e21 A 2.00 BS01 III B 1 T51 S53 L82 Q84 E127 F129 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 E230 Y235 P236 F239 A240 D241 P243 I246 Y247 Y330 T37 S39 L68 Q70 E113 F115 R119 K154 P155 E156 F173 L184 C185 G186 T187 P188 E189 Y190 L191 E216 Y221 P222 F225 A226 D227 P229 I232 Y233 Y316 2.7.11.11 P05132 VKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6e3v A 1.96 BS02 NUC P 1 G105 I106 G107 P108 S109 A110 M236 R254 D256 F272 G96 I97 G98 P99 S100 A101 M227 R245 D247 F263 2.7.7.7,4.2.99.- P06746 30817143 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 6e3x A 2.65 BS02 NUC P 1 S104 G105 I106 G107 S109 A110 R254 S98 G99 I100 G101 S103 A104 R246 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 6e8p A 1.90 BS02 HZJ A 1 H94 H96 H119 V121 V131 V135 L198 T199 T200 P202 H91 H93 H116 V118 V127 V131 L194 T195 T196 P198 4.2.1.1 P00918 30721041 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 6eds A 3.18 BS01 III C 1 G335 G339 E341 V360 G361 Q363 K364 E365 Y609 G293 G297 E299 V318 G319 Q321 K322 E323 Y567 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6eds A 3.18 BS02 III C 2 H108 Q111 H112 F115 S138 N139 A140 F141 T142 Y150 E189 A198 W199 F202 F820 R824 Y831 I832 V833 H66 Q69 H70 F73 S96 N97 A98 F99 T100 Y108 E147 A156 W157 F160 F778 R782 Y789 I790 V791 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6eds B 3.18 BS01 III D 1 G339 E341 L359 V360 G361 Q363 K364 E365 G297 E299 L317 V318 G319 Q321 K322 E323 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6eds B 3.18 BS02 III D 2 H108 Q111 H112 F115 S138 N139 A140 F141 T142 E189 W199 R824 Y831 V833 H66 Q69 H70 F73 S96 N97 A98 F99 T100 E147 W157 R782 Y789 V791 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6ftf B 1.09 BS01 7CI B 1 V411 V423 C424 F426 I432 G433 E434 L435 E436 V444 A445 V447 K482 Y483 Y485 Y486 V489 V201 V213 C214 F216 I222 G223 E224 L225 E226 V234 A235 V237 K272 Y273 Y275 Y276 V279 Q4DSV5 GIDPEKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVAGAMQRATFKHDDCIMEAGQTTCNKLYIIQSGHADIIKEGQKVYLKTEGTAVGELELMYDTPVVATVKVCTDELIAWVLDRDTYRNLVMGTAIRRRETYIQFLANVPFLGGLDSYEKLQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEVIGRDADGEPTKVCEFTQGDHIGELEFLNNHRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKRCADDPKYEYYQNVLKTGAAQPSYVD 6ftf B 1.09 BS02 7CI B 2 M272 I292 K294 Y300 V308 G309 E310 L311 E312 V320 A321 V323 Y371 M62 I82 K84 Y90 V98 G99 E100 L101 E102 V110 A111 V113 Y161 Q4DSV5 GIDPEKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVAGAMQRATFKHDDCIMEAGQTTCNKLYIIQSGHADIIKEGQKVYLKTEGTAVGELELMYDTPVVATVKVCTDELIAWVLDRDTYRNLVMGTAIRRRETYIQFLANVPFLGGLDSYEKLQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEVIGRDADGEPTKVCEFTQGDHIGELEFLNNHRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKRCADDPKYEYYQNVLKTGAAQPSYVD 6g7m S 1.71 BS01 SF4 S 1 H192 C195 R197 R198 C220 L221 C222 C226 G228 V249 H184 C187 R189 R190 C212 L213 C214 C218 G220 V241 1.12.99.6 P69741 PQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENKHNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAWGGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKNRPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLCHLGCKGPETYGNCSTLQFCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVE 6g7m S 1.71 BS03 SF4 S 2 C22 G24 C25 G118 S119 C120 V126 G153 C154 P155 C14 G16 C17 G110 S111 C112 V118 G145 C146 P147 1.12.99.6 P69741 PQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENKHNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAWGGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKNRPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLCHLGCKGPETYGNCSTLQFCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVE 6gck A 2.14 BS01 NAP A 1 G10 K13 R14 I15 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 Y174 K178 P204 G205 S207 L208 G9 K12 R13 I14 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L142 C143 Y157 K161 P187 G188 S190 L191 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gck B 2.14 BS01 NAP B 1 G10 R14 I15 Y34 H35 N36 S37 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 Y174 K178 P204 G205 S207 L208 G10 R14 I15 Y34 H35 N36 S37 D62 L63 T64 N93 A94 S95 T117 L142 C143 D144 Y157 K161 P187 G188 S190 L191 O76290 30908048 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gck B 2.14 BS02 EUB B 1 S95 F97 C168 F171 Y174 M213 W221 S95 F97 C151 F154 Y157 M196 W204 O76290 30908048 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gck C 2.14 BS02 EUB C 1 S95 F97 C168 Y174 M213 W221 S94 F96 C150 Y156 M195 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcl A 1.95 BS02 EUE A 1 S95 F97 D161 Y174 P210 W221 S94 F96 D143 Y156 P192 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcl B 1.95 BS02 EUE B 1 S95 F97 Y174 G205 V206 L209 P210 S94 F96 Y155 G186 V187 L190 P191 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcl C 1.95 BS02 EUE C 1 S95 F97 D161 Y174 G205 V206 P210 S94 F96 D141 Y154 G185 V186 P190 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcl D 1.95 BS02 EUE D 1 S95 F97 D161 Y174 L209 P210 M213 S94 F96 D142 Y155 L190 P191 M194 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcp A 1.52 BS01 NAP A 1 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 Y174 K178 P204 G205 V206 S207 L208 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L142 C143 D144 Y157 K161 P187 G188 V189 S190 L191 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcp A 1.52 BS02 EUK A 1 S95 F97 C168 F171 Y174 V206 L209 P210 M213 W221 S94 F96 C151 F154 Y157 V189 L192 P193 M196 W204 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcp B 1.52 BS02 EUK B 1 S95 F97 D161 C168 F171 Y174 V206 P210 M213 W221 S94 F96 D145 C152 F155 Y158 V190 P194 M197 W205 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcp C 1.52 BS02 EUK C 1 S95 F97 C168 Y174 L209 P210 M213 W221 S94 F96 C151 Y157 L192 P193 M196 W204 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcp D 1.52 BS02 EUK D 1 S95 F97 C168 F171 Y174 P210 M213 W221 S94 F96 C150 F153 Y156 P192 M195 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gcq D 1.58 BS02 EUH D 1 S95 F97 D161 Y174 V206 L209 P210 M213 W221 S94 F96 D143 Y156 V188 L191 P192 M195 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gd0 A 1.74 BS02 EV8 A 1 S95 F97 C168 Y174 V206 L209 P210 A212 M213 W221 S94 F96 C154 Y160 V192 L195 P196 A198 M199 W207 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gd0 B 1.74 BS02 EV8 B 1 S95 F97 C168 Y174 V206 M213 W221 S94 F96 C150 Y156 V188 M195 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gdo A 1.78 BS02 EVZ A 1 S95 F97 D161 C168 F171 Y174 P210 M213 W221 S94 F96 D141 C148 F151 Y154 P190 M193 W201 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gdo D 1.78 BS02 EVZ D 1 S95 F97 D161 C168 F171 Y174 P210 A212 M213 W221 S94 F96 D141 C148 F151 Y154 P190 A192 M193 W201 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gdp A 1.52 BS02 EVW A 1 S95 F97 D161 M163 C168 Y174 V206 W221 S95 F97 D145 M147 C152 Y158 V190 W205 O76290 30908048 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gdp B 1.52 BS02 EVW B 1 S95 F97 M163 C168 Y174 M213 W221 S95 F97 M148 C153 Y159 M198 W206 O76290 30908048 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gdp D 1.52 BS02 EVW D 1 S95 F97 M163 C168 Y174 V206 M213 W221 S94 F96 M145 C150 Y156 V188 M195 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gdy A 2.04 BS02 AKG A 1 Y131 F133 T184 H187 D189 N197 K204 H273 V275 Y131 F133 T184 H187 D189 N197 K204 H273 V275 1.14.11.- Q6NYC1 MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESFSLSPAAVADNVERADALQLSVEEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQ 6gex A 1.78 BS02 EWK A 1 S95 F97 C168 Y174 P210 M213 W221 S94 F96 C148 Y154 P190 M193 W201 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gex D 1.78 BS02 EWK D 1 S95 F97 Y98 P99 C168 Y174 P210 M213 W221 S94 F96 Y97 P98 C147 Y153 P189 M192 W200 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gey A 1.56 BS02 EWT A 1 S95 F97 D161 C168 Y174 V206 L209 P210 M213 W221 S95 F97 D145 C152 Y158 V190 L193 P194 M197 W205 O76290 30908048 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gey B 1.56 BS02 EWT B 1 S95 F97 D161 C168 F171 Y174 L209 M213 W221 S95 F97 D145 C152 F155 Y158 L193 M197 W205 O76290 30908048 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gey C 1.56 BS02 EWT C 1 S95 F97 D161 C168 Y174 L209 P210 M213 W221 S94 F96 D144 C151 Y157 L192 P193 M196 W204 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6gey D 1.56 BS02 EWT D 1 S95 F97 D161 C168 Y174 V206 P210 M213 W221 S94 F96 D143 C150 Y156 V188 P192 M195 W203 O76290 30908048 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 6h7p A 1.79 BS02 AYE A 1 L96 N98 G122 I123 D175 L91 N93 G117 I118 D166 Q0CCT3 TTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGTYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSEVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFR 6h7p A 1.79 BS03 AYE A 2 L72 D73 N98 L67 D68 N93 Q0CCT3 TTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGTYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSEVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFR 6h7p A 1.79 BS04 CYH B 1 T126 M182 T121 M173 Q0CCT3 TTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGTYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSEVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFR 6h7p B 1.79 BS02 AYE A 3 M244 V247 A248 M233 V236 A237 Q0CCT3 TTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGTYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSEGVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFR 6h7p B 1.79 BS03 CYH B 1 M219 Y222 S240 Q245 M208 Y211 S229 Q234 Q0CCT3 TTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGTYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSEGVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFR 6h7p B 1.79 BS04 FVH B 1 L15 G16 A17 M18 N37 R38 T39 K42 C70 L71 L72 A76 Q79 N98 I123 A125 P127 L10 G11 A12 M13 N32 R33 T34 K37 C65 L66 L67 A71 Q74 N93 I118 A120 P122 Q0CCT3 TTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGTYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSEGVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFR 6h82 b 3.78 BS01 III m 1 A71 L129 N130 A33 L91 N92 H9AZX8 30862777 QTADGRVGLVPVNSYVTLETDDLDTDEHPVTDAGTVALEPGESAPIVRYDLGQPAAVYAVGATDEANVEYELKVNNSKTVGGRTNSPLGVLNTPFSFVEKLGGAIPCETAATYWAHYSSDATGTVELAGRMHIEV 6h9v A 1.52 BS02 MG A 1 F487 E488 A528 P529 F266 E267 A307 P308 B5BTR7 30899001 TGSKPFTVPILTVEEMTNSRFPIPLEKLFTGPSGAFVVQPQNGRCTTDGVLLGTTQLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGLLTQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDGSTTHRNEPQQWVLPSYSGRNVHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLDCLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLVIPPNGYFRFDSWVNQFYTLAPM 6h9v B 1.52 BS03 MG B 1 F487 E488 A528 P529 M530 F260 E261 A301 P302 M303 B5BTR7 30899001 SKPFTVPILTVEEMTNSRFPIPLEKLFTGPSGAFVVQPQNGRCTTDGVLLGTTQLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGLLTQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTDFETHQNTKFTPVGVIQDTTHRNEPQQWVLPSYSGRNVHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLDCLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLVIPPNGYFRFDSWVNQFYTLAPM 6hak A 3.95 BS01 NUC T 1 W24 P25 L26 F61 L74 V75 D76 R78 I94 Q151 G152 Y183 C258 Q500 W24 P25 L26 F61 L74 V75 D76 R78 I94 Q151 G152 Y183 C258 Q500 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2,2.7.7.-,3.1.-.- P03366 30902895 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6hak A 3.95 BS02 NUC P 1 D185 N255 L289 R356 R358 G359 R448 Q475 D185 N255 L289 R356 R358 G359 R448 Q475 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2,2.7.7.-,3.1.-.- P03366 30902895 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6hak C 3.95 BS01 NUC E 1 W24 P25 L26 F61 I63 L74 D76 R78 I94 G152 C258 N265 Q500 W24 P25 L26 F61 I63 L74 D76 R78 I94 G152 C258 N265 Q500 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2,2.7.7.-,3.1.-.- P03366 30902895 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6hak C 3.95 BS02 NUC F 1 R72 N255 L289 R358 G359 Q475 R72 N255 L289 R358 G359 Q475 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2,2.7.7.-,3.1.-.- P03366 30902895 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDICKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTNSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 6hc9 A 2.40 BS02 FXW B 1 K104 P105 F106 M107 S108 S217 K218 G219 L239 S242 L247 K104 P105 F106 M107 S108 S217 K218 G219 L239 S242 L247 P19491 30891120 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGSG 6hcb A 1.90 BS02 D45 B 1 K104 P105 S108 S217 K218 G219 S242 K101 P102 S105 S214 K215 G216 S239 P19491 30891120 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECG 6hch A 1.60 BS02 ZN A 1 T9 T54 T9 T54 P19491 30891120 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 6hch B 1.60 BS01 D45 A 1 K104 P105 F106 S108 S217 K218 G219 S242 K104 P105 F106 S108 S217 K218 G219 S242 P19491 30891120 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECG 6hcu A 1.62 BS02 LYS A 1 K321 W349 Y351 A352 K240 W268 Y270 A271 6.1.1.6 Q8IDJ8 30894487 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRPA 6hcu A 1.62 BS03 HIS A 1 H435 H455 F456 H354 H374 F375 6.1.1.6 Q8IDJ8 30894487 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRPA 6hcu B 1.62 BS01 LYS A 1 K105 E107 R108 K28 E30 R31 6.1.1.6 Q8IDJ8 30894487 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSAQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRPA 6hcu B 1.62 BS02 FYB B 1 R330 T337 H338 N339 F342 E500 G554 L555 G556 R559 I570 R251 T258 H259 N260 F263 E421 G457 L458 G459 R462 I473 6.1.1.6 Q8IDJ8 30894487 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSAQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRPA 6hcv A 2.20 BS01 FYE A 1 R330 E332 T337 H338 N339 F342 E500 G554 G556 R559 I570 R245 E247 T252 H253 N254 F257 E415 G452 G454 R457 I468 6.1.1.6 Q8IDJ8 30894487 PRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFKLAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRPA 6hcw A 1.46 BS01 LYS A 1 G249 A250 A271 E273 R295 E311 Y313 N467 Y469 E471 G516 G205 A206 A227 E229 R251 E267 Y269 N423 Y425 E427 G472 6.1.1.6 Q5CR27 30894487 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6hcw A 1.46 BS02 FYB A 1 R295 E297 T302 H303 N304 F307 E464 L465 C466 N467 G518 L519 G520 R523 I534 R251 E253 T258 H259 N260 F263 E420 L421 C422 N423 G474 L475 G476 R479 I490 6.1.1.6 Q5CR27 30894487 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6hko A 3.42 BS01 NUC R 1 L373 R591 D627 D629 D631 L299 R506 D542 D544 D546 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hko A 3.42 BS02 NUC T 1 K462 K463 R468 R475 R481 Q592 P593 A1010 T1013 S1014 Y1018 R1600 E1616 T1617 K377 K378 R383 R390 R396 Q507 P508 A925 T928 S929 Y933 R1395 E1411 T1412 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hko A 3.42 BS06 G2P T 1 P593 D627 L1202 P508 D542 L1111 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hko B 3.42 BS01 NUC R 1 R204 S482 G483 V486 R495 Q720 Q724 K916 K924 R1037 H1038 R1065 R180 S458 G459 V462 R471 Q696 Q700 K892 K900 R1013 H1014 R1041 2.7.7.6 P22138 30913026 ARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hko B 3.42 BS02 NUC S 1 R219 S221 M451 Q479 F508 L512 R817 R195 S197 M427 Q455 F484 L488 R793 2.7.7.6 P22138 30913026 ARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hko B 3.42 BS03 NUC T 1 N197 I199 Q427 M430 N454 Y463 S466 T467 N739 Q1045 G1062 R1063 K1064 I1069 R1070 M1074 N173 I175 Q403 M406 N430 Y439 S442 T443 N715 Q1021 G1038 R1039 K1040 I1045 R1046 M1050 2.7.7.6 P22138 30913026 ARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hko B 3.42 BS05 G2P T 1 R714 R957 R690 R933 2.7.7.6 P22138 30913026 ARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hlq A 3.18 BS01 NUC R 1 L373 E464 K469 R591 D627 D629 D631 L299 E379 K384 R506 D542 D544 D546 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hlq A 3.18 BS03 NUC T 1 K462 K463 R475 R481 Q592 P593 S1014 G1017 Y1018 R1600 E1616 T1617 Q1620 K377 K378 R390 R396 Q507 P508 S929 G932 Y933 R1393 E1409 T1410 Q1413 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hlq A 3.18 BS07 G2P T 1 R591 P593 N625 R506 P508 N540 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hlq B 3.18 BS01 NUC R 1 R204 S482 R495 Q724 K916 K924 R1037 H1038 R181 S459 R472 Q701 K893 K901 R1014 H1015 2.7.7.6 P22138 30913026 QARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hlq B 3.18 BS02 NUC S 1 R219 S221 Q479 F508 R817 R196 S198 Q456 F485 R794 2.7.7.6 P22138 30913026 QARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hlq B 3.18 BS03 NUC T 1 I199 M430 N454 Y463 S466 T467 K513 N739 Q1045 R1063 I1069 R1070 M1074 I176 M407 N431 Y440 S443 T444 K490 N716 Q1022 R1040 I1046 R1047 M1051 2.7.7.6 P22138 30913026 QARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hlr A 3.18 BS01 NUC R 1 L373 K469 R591 D629 D631 L299 K384 R506 D544 D546 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hlr A 3.18 BS06 G2P T 1 P593 L1202 P508 L1111 2.7.7.6 P10964 30913026 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 6hlr B 3.18 BS02 NUC S 1 R219 S221 R225 D395 M451 Q479 F508 F509 L512 R817 R193 S195 R199 D369 M425 Q453 F482 F483 L486 R791 2.7.7.6 P22138 30913026 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hlr B 3.18 BS03 NUC T 1 N197 I199 M430 N454 Y463 S466 N739 Q1045 G1062 R1063 I1069 R1070 N171 I173 M404 N428 Y437 S440 N713 Q1019 G1036 R1037 I1043 R1044 2.7.7.6 P22138 30913026 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hlr B 3.18 BS05 G2P T 1 R714 Y717 R957 R688 Y691 R931 2.7.7.6 P22138 30913026 TADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPGYLGNKLSVSVEQVSIAKPMSNDAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 6hls I 3.21 BS02 ZN I 2 C89 C114 S116 C117 C71 C96 S98 C99 P32529 30913026 SVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKSVVKCPQCGNEEMNYHTLQLRSADEGATVFYTCTSCGYKFRTNN 6hwr C 1.95 BS03 H1T C 1 D135 D164 Y167 N201 H202 N294 H295 H296 E299 H323 H325 Y365 D127 D156 Y159 N193 H194 N286 H287 H288 E291 H315 H317 Y357 3.1.3.2 P80366 30719821 RDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDS 6hwr D 1.95 BS04 VN3 D 1 K67 R113 K61 R107 3.1.3.2 P80366 30719821 KNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGDYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST 6hzz A 2.52 BS01 SO4 A 1 Q202 R428 Y500 Y560 Y578 Q101 R322 Y394 Y454 Y472 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6hzz A 2.52 BS02 CA A 1 T238 E240 T268 N269 D392 T137 E139 T162 N163 D286 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6hzz B 2.52 BS01 SO4 B 1 R428 Y500 Y560 Y578 R327 Y399 Y459 Y477 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 A 2.10 BS01 BDP A 1 Q202 W203 R575 Q101 W102 R470 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 A 2.10 BS02 GNS A 1 Q202 R428 L430 Y500 Y560 R563 N572 R575 F578 Q101 R323 L325 Y395 Y455 R458 N467 R470 F473 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 A 2.10 BS03 BDP A 2 Q202 Y210 M445 E499 Y500 N510 Y560 F578 Q101 Y109 M340 E394 Y395 N405 Y455 F473 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 A 2.10 BS04 GNS A 2 Y180 R185 R187 Y210 Q213 Q216 M445 Y514 Y79 R84 R86 Y109 Q112 Q115 M340 Y409 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 A 2.10 BS05 BDP A 3 Y180 N181 R185 T581 Y79 N80 R84 T476 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 A 2.10 BS06 GNS A 3 S176 G179 S75 G78 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 B 2.10 BS01 BDP B 1 W203 R575 W102 R474 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 B 2.10 BS02 GNS B 1 Q202 R428 Y500 Y560 R563 N572 R575 F578 Q101 R327 Y399 Y459 R462 N471 R474 F477 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i01 B 2.10 BS04 GNS B 2 Y180 R185 R187 Y210 I212 Q213 Q216 M445 Y514 Y79 R84 R86 Y109 I111 Q112 Q115 M344 Y413 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i02 A 2.45 BS05 IDR A 3 Y180 N181 R185 D577 T581 Y79 N80 R84 D471 T475 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i02 B 2.45 BS02 IDR B 1 Q202 Y210 I212 M445 E499 Y500 N510 Y560 F578 Q101 Y109 I111 M344 E398 Y399 N409 Y459 F477 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6i02 B 2.45 BS03 GNS B 2 Y180 R185 R187 Q202 Y210 I212 Q213 Q216 M445 Y514 Y79 R84 R86 Q101 Y109 I111 Q112 Q115 M344 Y413 5.1.3.17 O94923 30872481 LKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKFLTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDFHTTHINQLQLLSTIDESPVFKEFVKRWKSYLKGSRAKHN 6ieg B 3.55 BS01 ATP B 1 F138 I139 D141 T163 S164 A165 G166 K167 T168 D252 E253 F46 I47 D49 T71 S72 A73 G74 K75 T76 D160 E161 3.6.4.13 P42285 30842217 ADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSDPLYVVEVLLRCSKESLKNSAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAA 6ieg A 3.55 BS01 ATP A 1 F138 I139 L140 Q144 S164 A165 G166 K167 T168 V169 D252 E253 F41 I42 L43 Q47 S67 A68 G69 K70 T71 V72 D151 E152 3.6.4.13 P42285 30842217 RVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKINEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKLYVVEVLLRCSKESLTEAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 6ieh B 2.89 BS01 ATP B 1 F138 I139 Q144 T163 S164 G166 K167 T168 K198 D252 E253 R527 F41 I42 Q47 T66 S67 G69 K70 T71 K101 D155 E156 R414 3.6.4.13 P42285 30842217 RVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 6if2 B 2.40 BS01 MG B 1 S22 T40 S22 T40 Q15286 MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGLERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAK 6if2 B 2.40 BS02 GTP B 1 S17 G18 V19 G20 K21 S22 S23 F33 S34 G35 S36 Y37 T39 T40 G66 N120 K121 D123 A151 K152 S17 G18 V19 G20 K21 S22 S23 F33 S34 G35 S36 Y37 T39 T40 G66 N120 K121 D123 A151 K152 Q15286 MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGLERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAK 6if3 B 1.50 BS01 GTP B 1 S17 G18 V19 G20 K21 S22 S23 F33 G35 Y37 T40 G66 N120 K121 D123 S150 A151 K152 S16 G17 V18 G19 K20 S21 S22 F32 G34 Y36 T39 G65 N119 K120 D122 S149 A150 K151 Q15286 ARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGLERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAK 6iid A 2.99 BS01 NUC E 1 R109 S137 R138 G139 A140 P143 A144 G145 K148 F168 N171 S172 N176 E179 M180 R183 Y310 L311 R314 R52 S80 R81 G82 A83 P86 A87 G88 K91 F111 N114 S115 N119 E122 M123 R126 Y253 L254 R257 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEE 6iid A 2.99 BS02 NUC F 1 K113 K115 D169 S172 N176 L311 K315 R320 R324 K56 K58 D112 S115 N119 L254 K258 R263 R267 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEE 6iid A 2.99 BS03 MG E 1 A140 N171 A83 N114 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEE 6iid B 2.99 BS01 NUC G 1 R109 S137 R138 G139 A140 P143 A144 G145 K148 F168 N171 S172 N176 E179 R183 L311 R314 R52 S80 R81 G82 A83 P86 A87 G88 K91 F111 N114 S115 N119 E122 R126 L254 R257 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGLEKIMENLKNAEIEPDDYFMSRYEKKLEE 6iid B 2.99 BS02 NUC H 1 F168 D169 S172 N176 L311 K315 F111 D112 S115 N119 L254 K258 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGLEKIMENLKNAEIEPDDYFMSRYEKKLEE 6iid B 2.99 BS03 MG B 1 G139 A140 N171 G82 A83 N114 3.1.30.- Q9Y2C4 EKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGLEKIMENLKNAEIEPDDYFMSRYEKKLEE 6iid C 2.99 BS02 NUC J 1 K113 D169 S172 N176 L311 R320 R324 K55 D111 S114 N118 L253 R262 R266 3.1.30.- Q9Y2C4 KAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEK 6iid D 2.99 BS01 NUC K 1 R109 K110 S137 R138 G139 A140 P143 A144 G145 K148 F168 N171 S172 N176 E179 M180 R183 Y310 L311 R314 R53 K54 S81 R82 G83 A84 P87 A88 G89 K92 F112 N115 S116 N120 E123 M124 R127 Y254 L255 R258 3.1.30.- Q9Y2C4 AEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKVLRLEKIMENLKNAEIEPDDYFMSRYEKK 6iid D 2.99 BS02 NUC L 1 D169 S172 N176 L311 K315 D113 S116 N120 L255 K259 3.1.30.- Q9Y2C4 AEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKVLRLEKIMENLKNAEIEPDDYFMSRYEKK 6inq A 6.90 BS02 NUC T 1 A310 K318 K333 R345 R351 Q448 T832 A833 Y837 E1410 A295 K303 K318 R330 R336 Q433 T817 A818 Y822 E1358 2.7.7.6 C4R4Y0 30287617 SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLP 6ir7 A 1.28 BS01 LDO A 1 D234 E235 L236 Y237 D228 E229 L230 Y231 P42212 30886277 GEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFVQCFSRYPDHMKRHDFFKSAMPEGYVQERTISFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYITADKQKNGIKANFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSKLSKDPNEKRDHMVLLEFVTAAGITHGMDELY 6irn A 3.87 BS01 NUC I 1 R40 Y41 V46 A47 R49 R63 K64 L65 R69 R4 Y5 V10 A11 R13 R27 K28 L29 R33 A0A310TTQ1 30872815 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6irn A 3.87 BS02 NUC J 1 R42 T45 R72 R83 F84 Q85 R116 V117 T118 R6 T9 R36 R47 F48 Q49 R80 V81 T82 A0A310TTQ1 30872815 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6irn B 3.87 BS01 NUC I 1 R23 I46 R78 K79 T80 R10 I33 R65 K66 T67 P62799 30872815 GAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6irn B 3.87 BS02 NUC J 1 R36 R45 R23 R32 P62799 30872815 GAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6irn C 3.87 BS01 NUC I 1 R42 V43 G44 A45 K75 T76 R77 R31 V32 G33 A34 K64 T65 R66 Q6AZJ8 30872815 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6irn C 3.87 BS02 NUC J 1 A12 A14 K15 R17 R32 R42 R77 A1 A3 K4 R6 R21 R31 R66 Q6AZJ8 30872815 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6irn D 3.87 BS01 NUC I 1 K31 E32 Y37 K3 E4 Y9 P02281 30872815 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6irn D 3.87 BS02 NUC J 1 T29 R30 G50 S52 S53 S84 T85 T1 R2 G22 S24 S25 S56 T57 P02281 30872815 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6irn E 3.87 BS01 NUC I 1 R42 T45 R72 R83 F84 Q85 R116 T118 R3 T6 R33 R44 F45 Q46 R77 T79 A0A310TTQ1 30872815 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6irn H 3.87 BS01 NUC I 1 T29 R30 G50 I51 S52 S53 S84 T85 T1 R2 G22 I23 S24 S25 S56 T57 P02281 30872815 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6irn H 3.87 BS02 NUC J 1 R30 K31 Y37 R2 K3 Y9 P02281 30872815 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6irn K 3.87 BS01 NUC I 1 R328 K330 S334 M335 W600 N601 R639 K643 R145 K147 S151 M152 W406 N407 R445 K449 3.6.4.- P38144 30872815 QFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTS 6irn K 3.87 BS02 NUC J 1 K254 K280 R283 E304 R308 L466 M470 K474 M527 S528 D549 R557 T577 R579 K71 K97 R100 E121 R125 L272 M276 K280 M333 S334 D355 R363 T383 R385 3.6.4.- P38144 30872815 QFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTS 6irn K 3.87 BS03 ADP K 1 Q195 Q200 M223 G224 G226 K227 T228 L229 E263 N586 Q12 Q17 M40 G41 G43 K44 T45 L46 E80 N392 3.6.4.- P38144 30872815 QFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTS 6irn K 3.87 BS04 BEF K 1 T228 D324 E325 T45 D141 E142 3.6.4.- P38144 30872815 QFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQQNRTS 6iro L 3.40 BS01 NUC I 1 K330 S334 M335 L336 N358 I468 W600 N601 K185 S189 M190 L191 N213 I312 W444 N445 3.6.4.- P38144 30872815 DLEGTTKRFEHLLSLSGLFKHFIESKKFRQVLDVLEENQFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFKGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQ 6iro L 3.40 BS02 NUC J 1 K254 K280 R283 E304 R308 L466 N467 M470 K474 M527 S528 R529 D549 R557 T577 A580 K109 K135 R138 E159 R163 L310 N311 M314 K318 M371 S372 R373 D393 R401 T421 A424 3.6.4.- P38144 30872815 DLEGTTKRFEHLLSLSGLFKHFIESKKFRQVLDVLEENQFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFKGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQ 6iro L 3.40 BS03 ADP L 1 R197 Q200 M223 G224 L225 G226 K227 T228 L229 E263 R266 R52 Q55 M78 G79 L80 G81 K82 T83 L84 E118 R121 3.6.4.- P38144 30872815 DLEGTTKRFEHLLSLSGLFKHFIESKKFRQVLDVLEENQFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADEMGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIASYEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFDDWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLRKCCNHPYLFKGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTAHEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVEEKILERATQKLRLDQLVIQ 6iro B 3.40 BS02 NUC J 1 P32 R36 P18 R22 P62799 30872815 AKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 6iro C 3.40 BS02 NUC J 1 A12 A14 K15 R17 R20 G28 R32 R77 A1 A3 K4 R6 R9 G17 R21 R66 Q6AZJ8 30872815 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6iro D 3.40 BS01 NUC I 1 T29 R30 K31 I36 Y37 T1 R2 K3 I8 Y9 P02281 30872815 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6iro E 3.40 BS01 NUC I 1 R42 T45 R63 R72 R83 F84 Q85 V117 T118 R3 T6 R24 R33 R44 F45 Q46 V78 T79 A0A310TTQ1 30872815 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6iro E 3.40 BS02 NUC J 1 R40 Y41 V46 A47 R49 R63 K64 L65 R69 R83 R1 Y2 V7 A8 R10 R24 K25 L26 R30 R44 A0A310TTQ1 30872815 RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 6iro F 3.40 BS01 NUC I 1 R17 H18 R36 R45 R1 H2 R20 R29 P62799 30872815 RHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 6iro G 3.40 BS01 NUC I 1 A14 K15 T16 R17 R20 R32 R77 A3 K4 T5 R6 R9 R21 R66 Q6AZJ8 30872815 AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 6iro H 3.40 BS01 NUC I 1 G50 I51 S53 R83 S84 T85 G22 I23 S25 R55 S56 T57 P02281 30872815 TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 6ive A 2.30 BS01 ZN A 1 H65 H87 H64 H86 Q5SH51 30895492 SVYRFEDKTPAVHPTAFIAPGAYVVGAVEVGEGASIWFGAVVRGDLERVVVGPGTNVQDGAVLHADPGFPCLLGPEVTVGHRAVVHGAVVEEGALVGMGAVVLNGARIGKNAVVGAGAVVPPGMEVPEGRLALGVPARVVRPIDPPGNAPRYRALAERYRKALFPVAT 6ive A 2.30 BS02 PO4 A 1 H65 D67 H87 H64 D66 H86 Q5SH51 30895492 SVYRFEDKTPAVHPTAFIAPGAYVVGAVEVGEGASIWFGAVVRGDLERVVVGPGTNVQDGAVLHADPGFPCLLGPEVTVGHRAVVHGAVVEEGALVGMGAVVLNGARIGKNAVVGAGAVVPPGMEVPEGRLALGVPARVVRPIDPPGNAPRYRALAERYRKALFPVAT 6ive A 2.30 BS03 PO4 A 2 Q59 H82 N149 R152 Y153 Q58 H81 N148 R151 Y152 Q5SH51 30895492 SVYRFEDKTPAVHPTAFIAPGAYVVGAVEVGEGASIWFGAVVRGDLERVVVGPGTNVQDGAVLHADPGFPCLLGPEVTVGHRAVVHGAVVEEGALVGMGAVVLNGARIGKNAVVGAGAVVPPGMEVPEGRLALGVPARVVRPIDPPGNAPRYRALAERYRKALFPVAT 6ive B 2.30 BS01 PO4 A 1 Q59 H82 N149 Y153 Q57 H80 N147 Y151 Q5SH51 30895492 VYRFEDKTPAVHPTAFIAPGAYVVGAVEVGEGASIWFGAVVRGDLERVVVGPGTNVQDGAVLHADPGFPCLLGPEVTVGHRAVVHGAVVEEGALVGMGAVVLNGARIGKNAVVGAGAVVPPGMEVPEGRLALGVPARVVRPIDPPGNAPRYRALAERYRKALFPV 6ive C 2.30 BS03 PO4 C 1 Q59 N149 Y153 Q59 N149 Y153 Q5SH51 30895492 MSVYRFEDKTPAVHPTAFIAPGAYVVGAVEVGEGASIWFGAVVRGDLERVVVGPGTNVQDGAVLHADPGFPCLLGPEVTVGHRAVVHGAVVEEGALVGMGAVVLNGARIGKNAVVGAGAVVPPGMEVPEGRLALGVPARVVRPIDPPGNAPRYRALAERYRKALFPVA 6ive F 2.30 BS02 PO4 E 1 Q59 H82 M99 N149 Y153 Q58 H81 M98 N148 Y152 Q5SH51 30895492 SVYRFEDKTPAVHPTAFIAPGAYVVGAVEVGEGASIWFGAVVRGDLERVVVGPGTNVQDGAVLHADPGFPCLLGPEVTVGHRAVVHGAVVEEGALVGMGAVVLNGARIGKNAVVGAGAVVPPGMEVPEGRLALGVPARVVRPIDPPGNAPRYRALAERYRKALFPVAT 6ixm B 1.60 BS01 NAD B 1 G13 S16 G17 I18 D37 I38 A62 D63 T64 N90 A91 G92 M141 A142 Y156 K160 P186 A187 Y188 I189 G12 S15 G16 I17 D36 I37 A61 D62 T63 N89 A90 G91 M140 A141 Y155 K159 P185 A186 Y187 I188 X2D0L0 30885322 GILDNKVALVTGAGSGIGLAVAHSYAKEGAKVIVSDINEDHGNKAVEDIKAQGGEASFVKADTSNPEEVEALVKRTVEIYGRLDIACNNAGIGGEQALAGDYGLDSWRKVLSINLDGVFYGCKYELEQMEKNGGGVIVNMASIHGIVAAPLSSAYTSAKHAVVGLTKNIGAEYGQKNIRCNAVGPAYIEMKEALISKHPMGRLGKPEEVAELVLFLSSEKSSFMTGGYYLVDGGYTAV 6ixm C 1.60 BS01 NAD C 1 G13 S16 G17 I18 D37 I38 A62 D63 T64 N90 A91 M141 A142 S143 Y156 K160 P186 A187 Y188 I189 L193 G12 S15 G16 I17 D36 I37 A61 D62 T63 N89 A90 M140 A141 S142 Y155 K159 P185 A186 Y187 I188 L192 X2D0L0 30885322 GILDNKVALVTGAGSGIGLAVAHSYAKEGAKVIVSDINEDHGNKAVEDIKAQGGEASFVKADTSNPEEVEALVKRTVEIYGRLDIACNNAGIGGEQALAGDYGLDSWRKVLSINLDGVFYGCKYELEQMEKNGGGVIVNMASIHGIVAAPLSSAYTSAKHAVVGLTKNIGAEYGQKNIRCNAVGPAYIETPLLESLTKEMKEALISKHPMGRLGKPEEVAELVLFLSSEKSSFMTGGYYLVDGGYTAV 6iy2 A 3.47 BS01 NUC J 1 Y41 R42 P43 T45 R63 R72 R83 F84 R116 V117 T118 Y6 R7 P8 T10 R28 R37 R48 F49 R81 V82 T83 A0A310TTQ1 30867599 KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 6iy2 A 3.47 BS02 NUC I 1 R40 Y41 G44 V46 A47 R49 K56 R63 L65 P66 R69 R83 R5 Y6 G9 V11 A12 R14 K21 R28 L30 P31 R34 R48 A0A310TTQ1 30867599 KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 6iy2 C 3.47 BS01 NUC J 1 R11 A14 K15 R17 R20 R32 R42 R77 R1 A4 K5 R7 R10 R22 R32 R67 Q6AZJ8 30867599 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKKTE 6iy2 D 3.47 BS01 NUC J 1 R30 T32 R33 Y42 G53 I54 S55 S56 R86 S87 T88 R5 T7 R8 Y17 G28 I29 S30 S31 R61 S62 T63 A0A1L8FQA5 30867599 GKKRRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy2 D 3.47 BS02 NUC I 1 K27 K31 T32 R33 K34 I39 Y40 K2 K6 T7 R8 K9 I14 Y15 A0A1L8FQA5 30867599 GKKRRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy2 E 3.47 BS01 NUC J 1 K37 H39 R40 Y41 P43 G44 V46 A47 R49 R63 K64 L65 P66 R69 R83 K1 H3 R4 Y5 P7 G8 V10 A11 R13 R27 K28 L29 P30 R33 R47 A0A310TTQ1 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 6iy2 E 3.47 BS02 NUC I 1 R42 P43 T45 R63 R83 F84 V117 T118 R6 P7 T9 R27 R47 F48 V81 T82 A0A310TTQ1 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 6iy2 G 3.47 BS02 NUC I 1 R11 A12 K13 A14 T16 R17 R20 R32 R42 R77 R3 A4 K5 A6 T8 R9 R12 R24 R34 R69 Q6AZJ8 30867599 KTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPKK 6iy2 H 3.47 BS01 NUC J 1 K31 K34 E35 I39 Y40 K3 K6 E7 I11 Y12 A0A1L8FQA5 30867599 RRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy2 H 3.47 BS02 NUC I 1 R30 T32 R33 Y42 G53 S56 R86 S87 T88 R2 T4 R5 Y14 G25 S28 R58 S59 T60 A0A1L8FQA5 30867599 RRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy2 O 3.47 BS01 NUC J 1 L825 S826 R854 E874 Y875 N1050 M1053 Q1054 K1057 M1112 T1113 Q1114 G1135 S1162 G1166 L104 S105 R133 E153 Y154 N309 M312 Q313 K316 M371 T372 Q373 G394 S421 G425 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 6iy2 O 3.47 BS02 NUC I 1 K885 R898 K900 N901 S904 K905 L906 N929 I1052 R1164 W1185 N1186 R1224 K164 R177 K179 N180 S183 K184 L185 N208 I311 R423 W444 N445 R483 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 6iy2 O 3.47 BS03 ADP O 1 T766 K768 Q771 E793 M794 G795 L796 G797 K798 T799 I800 T45 K47 Q50 E72 M73 G74 L75 G76 K77 T78 I79 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 6iy3 A 3.67 BS01 NUC J 1 H39 R40 R42 P43 T45 R63 R83 F84 Q85 R116 V117 T118 H4 R5 R7 P8 T10 R28 R48 F49 Q50 R81 V82 T83 A0A310TTQ1 30867599 KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 6iy3 D 3.67 BS01 NUC J 1 R29 R30 T32 R33 E35 Y42 G53 S56 R86 S87 T88 R2 R3 T5 R6 E8 Y15 G26 S29 R59 S60 T61 A0A1L8FQA5 30867599 KRRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy3 D 3.67 BS02 NUC I 1 K31 R33 E35 I39 Y40 K4 R6 E8 I12 Y13 A0A1L8FQA5 30867599 KRRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy3 E 3.67 BS02 NUC I 1 K37 R40 Y41 R42 P43 T45 R63 R72 R83 F84 R116 V117 T118 K1 R4 Y5 R6 P7 T9 R27 R36 R47 F48 R80 V81 T82 A0A310TTQ1 30867599 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 6iy3 G 3.67 BS01 NUC J 1 K13 R29 R42 V43 A45 K75 R77 K5 R21 R34 V35 A37 K67 R69 Q6AZJ8 30867599 KTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6iy3 G 3.67 BS02 NUC I 1 R11 A14 K15 T16 R17 R20 R32 R77 R3 A6 K7 T8 R9 R12 R24 R69 Q6AZJ8 30867599 KTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLP 6iy3 H 3.67 BS02 NUC I 1 R29 R30 T32 R33 Y42 G53 I54 S56 R86 T88 R1 R2 T4 R5 Y14 G25 I26 S28 R58 T60 A0A1L8FQA5 30867599 RRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 6iy3 O 3.67 BS02 NUC I 1 L825 S826 R854 E874 Y875 K878 N1049 N1050 M1053 Q1054 K1057 M1112 T1113 Q1114 G1135 R1142 S1162 G1166 L104 S105 R133 E153 Y154 K157 N308 N309 M312 Q313 K316 M371 T372 Q373 G394 R401 S421 G425 3.6.4.- P22082 30867599 LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTRMDEDRSKKEEKSRLLEKKREESESAAVYNG 6iym A 2.10 BS01 MG A 1 E124 E126 D155 E123 E125 D154 K0A9N9 30630595 SMKWFRFEQDGRARIGVEEAGHRYDVTPQVYTDSLLEVIVRGFEMDVDLDVAPRLTDHVRLLAPYLPPRNVICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFDPIERHADLTQQLDYEGELAIIIGTTGRDLTPENALEHVFGYSIINDVTARDLQKEHVQFFRGKSLDGFCPFGPVIVTEDAFDPADVLVETRVNGELRQSGSTKLMLRDVVTILTEVSRGMTLEAGDVIATGTPAGVGHGMKPPVYLQDGDVIDVSIEGIGHLQNQVKAR 6iym B 2.10 BS01 MG B 1 V75 E124 E126 D155 V74 E123 E125 D154 K0A9N9 30630595 SMKWFRFEQDGRARIGVEEAGHRYDVTPQVYTDSLLEVIVRGFEMDVDLDVAPRLTDHVRLLAPYLPPRNVICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFDPIERHADLTQQLDYEGELAIIIGTTGRDLTPENALEHVFGYSIINDVTARDLQKEHVQFFRGKSLDGFCPFGPVIVTEDAFDPADVLVETRVNGELRQSGSTKLMLRDVVTILTEVSRGMTLEAGDVIATGTPAGVGHGMKPPVYLQDGDVIDVSIEGIGHLQNQVKAR 6j06 A 2.65 BS01 99C A 1 W350 H351 Y352 K393 R412 R418 R469 L471 W54 H55 Y56 K97 R116 R122 R173 L175 O00481 GAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA 6j06 B 2.65 BS01 99C B 1 W350 H351 Y352 W391 R412 R418 R469 L471 W54 H55 Y56 W95 R116 R122 R173 L175 O00481 GAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA 6j06 B 2.65 BS02 CA B 1 E358 S359 F360 E62 S63 F64 O00481 GAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA 6j06 C 2.65 BS01 99C C 1 W350 H351 Y352 R412 R418 R469 L471 W54 H55 Y56 R116 R122 R173 L175 O00481 GAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA 6j0g A 1.60 BS01 H6P A 1 H351 Y352 K394 R413 R419 R470 L472 H56 Y57 K99 R118 R124 R175 L177 O00478 GAAYHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWHYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPIP 6j0g B 1.60 BS01 H6P B 1 W350 H351 Y352 K394 R413 R419 R470 L472 W55 H56 Y57 K99 R118 R124 R175 L177 O00478 GAAYHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWHYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPIP 6j0l A 1.95 BS01 SO4 A 1 K394 P418 R419 K96 P120 R121 O00478 YHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWHYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPIP 6j0l A 1.95 BS02 SO4 A 2 R413 R419 R470 R115 R121 R172 O00478 YHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWHYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPIP 6j0l B 1.95 BS01 SO4 A 1 R413 R419 R116 R122 O00478 AYHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWHYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPI 6j0l B 1.95 BS02 SO4 B 1 K394 R413 R419 R470 K97 R116 R122 R173 O00478 AYHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWHYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPTALTICPI 6j5u C 3.90 BS01 BQL C 1 H251 V252 K255 H69 V70 K71 2.7.11.1 O49839 MPKGSLENHLFRRGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRDFKAANILLDADFNAKLSDFTHVKVIGTHGYAAPEYVATGRLTAKSDVYSFGVVLLELISGRRAMDNYSLVDWATPYLLFRIMDTKLGGQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLE 6j5u C 3.90 BS02 BQO C 1 V252 K255 V256 V70 K71 V72 2.7.11.1 O49839 MPKGSLENHLFRRGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRDFKAANILLDADFNAKLSDFTHVKVIGTHGYAAPEYVATGRLTAKSDVYSFGVVLLELISGRRAMDNYSLVDWATPYLLFRIMDTKLGGQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLE 6j5u B 3.90 BS01 BQL C 1 V70 K193 F212 L229 G230 T231 V54 K173 F192 L209 G210 T211 Q9SVY5 DKAKRWFLDNGSIFLRELVADCNGKSIPIRSFSPEQILKATNNFDSSCFVSQDVYYKWYRGEIEDRSYMIKRFSEDEITGKRHRVKEVYNDIVLSARMSNHSNFLQLLGCCLEFPFPVLVFEFAEHGAMNQRGGVIVNLLPWSVRLKIGKEIANAVTYLHTAFPKIIIHRDVKPMHVFLDKNWTAKLSDLSFSISLPEGKSRIEAEWVLGTFGYIDPLYHKTCFVTEYTDVYSFGICLLVIITGKPAIMTISDGDLQGILSLVRELCENGKLDEVIDPRLMKDITSGQRLQVEACVVLALRCCKERDEDRPKMIQVAKELKQIEASL 6j5v C 4.25 BS01 BQL C 1 H251 V252 H69 V70 2.7.11.1 O49839 MPKGSLENHLFRRGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRDFKAANILLDADFNAKLSDFTHVKVIGTHGYAAPEYVATGRLTAKSDVYSFGVVLLELISGRRAMDNYSLVDWATPYLLFRIMDTKLGGQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLE 6j5v B 4.25 BS01 BQL C 1 V70 M195 L229 G230 T231 V54 M175 L209 G210 T211 Q9SVY5 DKAKRWFLDNGSIFLRELVADCNGKSIPIRSFSPEQILKATNNFDSSCFVSQDVYYKWYRGEIEDRSYMIKRFSEDEITGKRHRVKEVYNDIVLSARMSNHSNFLQLLGCCLEFPFPVLVFEFAEHGAMNQRGGVIVNLLPWSVRLKIGKEIANAVTYLHTAFPKIIIHRDVKPMHVFLDKNWTAKLSDLSFSISLPEGKSRIEAEWVLGTFGYIDPLYHKTCFVTEYTDVYSFGICLLVIITGKPAIMTISDGDLQGILSLVRELCENGKLDEVIDPRLMKDITSGQRLQVEACVVLALRCCKERDEDRPKMIQVAKELKQIEASL 6j5w A 3.70 BS01 ADP A 1 V160 V161 L163 G192 G194 K195 T196 T197 L326 P359 K363 H488 V129 V130 L132 G161 G163 K164 T165 T166 L295 P328 K332 H457 Q38834 MVDAVVTVFLEKTLNILEEKGRTVSDYRKQLEDLQSELKYMQSFLKDAERQKRTNETLRTLVADLRELVYEAEDILVDCQLADGDDGNEQRSSNAWLSRLHPARVPLQYKKSKNGTDRWSSPVYDHTQVVGLEGDKRKIKEWLFRSNDSQLLIMAFVGMGGLGKTTIAQEVFNDKEIEHRFERRIWVSVSQTFTEEQIMRSILRNLGDASVGDDIGTLLRKIQQYLLGKRYLIVMDDVWDKNLSWWDKIYQGLPRGQGGSVIVTTRSESVAKRVQARDDKTHRPELLSPDNSWLLFCNVAFAANDGTCERPELEDVGKEIVTKCKGLPLTIKAVGGLLLCKDHVYHEWRRIAEHFQDELRGNTSETDNVMSSLQLSYDELPSHLKSCILTLSLYPEDCVIPKQQLVHGWIGEGFVMWRNGRSATESGEDCFSGLTNRCLIEVVDKTYSGTIITCKIHDMVRDLVIDIAKKDSFSNPEGLNCRHLGISGNFDEKQIKVNHKLRGVVSTTKTGEVNKLNSDLAKKFTDCKYLRVLDISKSIFDAPLSEILDEIASLQHLACLSLSNTHPLIQFPRSMEDLHNLQILDASYCQNLKQLQPCIVLFKKLLVLDMTNCGSLECFPKGIGSLVKLEVLLGFKPARSNNGCKLSEVKNLTNLRKLGLSLTRGDQIEEEELDSLINLSKLMSISINCYDSYGDDLITKIDALTPPHQLHELSLQFYPGKSSPSWLSPHKLPMLRYMSICSGNLVKMQEPFWGNENTHWRIEGLMLSSLSDLDMDWEVLQQSMPYLRTVTANWCPELESFAIEDVGFRGGVWMKT 6jh5 A 1.54 BS01 CA A 1 E30 G68 D245 E10 G48 D225 QNWTLVWQDEFTNGISSDWVFETGNGNSGWGNNELQYYRRENATVENGNLVITAKRESIGGYNYTSTRMKTQGRKSWKYGKVEARIAMPSFMGSWPAFWMLGDNISSVGWPACGEIDIMEHVNTEAQTHGTIHWQDHNNTYANYSGSIPVSSVTSYHIYTIEWDASVIKWFVDGNLYHEASIANGVNGTSEFHNNFFILLNMAIGGNWPGFNIDNNAFPARMLVDYVRVYQK 6jo3 A 2.35 BS01 1GP A 1 L21 F78 Y171 E173 S176 G177 G201 G202 G203 T223 G224 T225 L21 F78 Y171 E173 S176 G177 G201 G202 G203 T223 G224 T225 2.5.1.41 Q9HJH3 MMTVLEDMLRKTRNGKVHMTLIDPGAKPPQECARIAEEAEMAGTDFIMVGGSTDIDSRAMDEAISAIKAKTDLKVIIFPGSSLMISPKADAIFFMSLLNSGSLEYVVGHQVKAAIPLSAMKIEKIPMAYLVFDPGMTVGRVGKAHLIPRDDEKTALSYALAAQYFGFRLVYFEAGSGSPYHVGENVVRRVKQELDIPVIVGGGIRTPEAAKALAQAGADMIVTGTIAERSVNVYEALHPIVESIKEV 6jog A 2.30 BS01 ASC A 1 G10 T11 F12 H19 R92 S129 S130 G10 T11 F12 H19 R92 S129 S130 2.7.7.3 A0A059ZFC5 MSKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKNPLFSLEERVALAQSSLGHLSNVEFVGFDGLLVNFFKEQKATAVLRGLRAVSDFEYEFQLANMNRQLDPHFEAVFLTPSEQYSFISSTLIREIARLKGDVTKFVPQAVVEAFERKHQQGW 6m90 A 2.05 BS01 III C 1 Y271 R285 S309 L311 S325 L351 K365 A391 A392 N394 G408 A434 R474 Y488 R521 F523 Y125 R139 S163 L165 S179 L205 K219 A245 A246 N248 G262 A288 R328 Y342 R375 F377 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 6m90 A 2.05 BS02 J91 A 1 N394 G408 R410 R431 G432 I433 A434 S448 L472 N248 G262 R264 R285 G286 I287 A288 S302 L326 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 6m90 A 2.05 BS03 J91 A 2 D409 R410 D263 R264 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 6m91 A 2.40 BS01 III C 1 Y271 R285 S309 L311 S325 L351 K365 A392 N394 G408 L472 R474 Y488 F523 Y125 R139 S163 L165 S179 L205 K219 A246 N248 G262 L326 R328 Y342 F377 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 6m91 A 2.40 BS02 J97 A 1 N394 G408 R410 R431 G432 A434 S448 L472 Y488 N248 G262 R264 R285 G286 A288 S302 L326 Y342 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLN 6m92 A 2.35 BS01 III C 1 Y271 R285 S309 L311 S325 L351 A391 A392 N394 G408 R474 Y488 R521 F523 Y125 R139 S163 L165 S179 L205 A245 A246 N248 G262 R328 Y342 R375 F377 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFL 6m92 A 2.35 BS02 J8V A 1 N394 G408 R410 R431 G432 I433 A434 S448 Y488 N248 G262 R264 R285 G286 I287 A288 S302 Y342 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFL 6m93 A 2.50 BS02 J8Y A 1 N394 G408 R431 G432 I433 A434 S448 L472 N249 G263 R286 G287 I288 A289 S303 L327 Q9Y297 SMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFL 6m97 A 3.03 BS01 TBR A 1 K1059 D1060 H1063 K100 D101 H104 C0HAK2 MTFYFGYTNVELLFASLVINTPGEMVAACFGCFLLAVLYEGLKIGREFLLRRNDLEDNWETLNDNLKVIEAAQVKDALTKMRAAALDAQKATPPKSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYQRMLSMAHLLQTVLHVIQVVVSYFLMLVFMTYNAYLCMAVAAGAGLGYFLFSWKKAVVVDIT 6m97 A 3.03 BS02 TBR A 2 R1034 D1066 V1069 G1070 D1073 R82 D107 V110 G111 D114 C0HAK2 MTFYFGYTNVELLFASLVINTPGEMVAACFGCFLLAVLYEGLKIGREFLLRRNDLEDNWETLNDNLKVIEAAQVKDALTKMRAAALDAQKATPPKSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYQRMLSMAHLLQTVLHVIQVVVSYFLMLVFMTYNAYLCMAVAAGAGLGYFLFSWKKAVVVDIT 6mhu F 4.00 BS01 JSG G 1 L22 F26 Q29 R33 L66 M303 Y306 L307 L18 F22 Q25 R29 L62 M265 Y268 L269 P0AF98 30894744 RYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQSVVVADSGHLTQLQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWD 6mhu G 4.00 BS01 JSG G 1 L29 S30 I33 K34 D37 K62 I66 F67 M70 L74 Y141 I313 F317 Y320 L24 S25 I28 K29 D32 K57 I61 F62 M65 L69 Y136 I295 F299 Y302 P0ADC6 30894744 VLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVNLTPDKLGVVALDPDALSISGLHNYVKYAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRK 6mhz A 4.10 BS01 AOV A 1 Y13 N38 G39 A40 G41 K42 T43 T44 Q85 E163 H195 Y12 N37 G38 A39 G40 K41 T42 T43 Q84 E162 H194 3.6.3.- P0A9V1 30894744 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLG 6mhz A 4.10 BS02 AOV B 1 S137 S139 G140 G141 G167 S136 S138 G139 G140 G166 3.6.3.- P0A9V1 30894744 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLG 6mhz B 4.10 BS01 AOV A 1 S137 S139 G140 G141 E142 G167 S136 S138 G139 G140 E141 G166 3.6.3.- P0A9V1 30894744 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLG 6mhz B 4.10 BS02 AOV B 1 Y13 P37 N38 G39 A40 G41 K42 T43 T44 Q85 E163 H195 Y12 P36 N37 G38 A39 G40 K41 T42 T43 Q84 E162 H194 3.6.3.- P0A9V1 30894744 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLG 6mi7 F 4.20 BS01 III C 1 Q293 L300 P301 L304 L305 L307 L308 L311 I312 T314 S315 Q163 L170 P171 L174 L175 L177 L178 L181 I182 T184 S185 P0AF98 30894744 IIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNDPTLWMWTVNLIYLALAIVLNLWDTVPV 6mi7 G 4.20 BS01 III C 1 L29 I32 I33 V36 L24 I27 I28 V31 P0ADC6 30894744 VLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQPDALSISGLHNYVKYAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS 6mi8 A 4.30 BS01 AOV A 1 P37 N38 G39 G41 K42 T43 T44 Q85 H195 P36 N37 G38 G40 K41 T42 T43 Q84 H194 3.6.3.- P0A9V1 30894744 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLG 6mi8 B 4.30 BS01 AOV A 1 L130 S137 S139 G140 G141 G167 L129 S136 S138 G139 G140 G166 3.6.3.- P0A9V1 30894744 ATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLG 6mjm A 2.20 BS01 HEM A 1 R105 I118 S119 W126 R130 F137 A305 G306 T309 V313 V369 A370 R375 P433 F434 G435 R439 N440 C441 I442 G443 A447 M451 R80 I93 S94 W101 R105 F112 A262 G263 T266 V270 V326 A327 R332 P390 F391 G392 R396 N397 C398 I399 G400 A404 M408 1.14.14.1 P20815 GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSDFLQLMIDSQKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRD 6mnc B 2.40 BS01 J3Z B 1 V143 Y155 P187 Y218 H221 F259 E282 V143 Y155 P187 Y210 H213 F251 E274 1.1.1.62 P14061 30768851 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVF 6mne A 1.86 BS01 NAP A 1 G9 S11 S12 G13 I14 R37 L64 D65 V66 A91 G92 L93 T190 G9 S11 S12 G13 I14 R37 L64 D65 V66 A91 G92 L93 T190 1.1.1.62 P14061 30768851 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFG 6mne A 1.86 BS02 J3Z A 1 V143 L149 H221 S222 F259 M279 E282 V283 V143 L149 H214 S215 F252 M272 E275 V276 1.1.1.62 P14061 30768851 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFG 6mne B 1.86 BS01 NAP B 1 G9 S11 S12 G13 I14 R37 L64 D65 V66 R67 A91 G92 T190 G9 S11 S12 G13 I14 R37 L64 D65 V66 R67 A91 G92 T190 1.1.1.62 P14061 30768851 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFG 6mne B 1.86 BS02 J3Z B 1 V143 Y155 H221 F226 F259 M279 E282 V283 V143 Y155 H214 F219 F252 M272 E275 V276 1.1.1.62 P14061 30768851 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFG 6mpx A 1.90 BS01 CL A 1 F64 N66 Y636 F61 N63 Y633 P08572 HGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMGTGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMAPGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 6mpx A 1.90 BS02 CL A 2 A521 R523 N524 D525 G625 A518 R520 N521 D522 G622 P08572 HGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMGTGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMAPGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 6mpx A 1.90 BS03 CL A 3 Y412 F511 N513 Y409 F508 N510 P08572 HGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMGTGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMAPGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 6mpx A 1.90 BS04 CL A 4 Y189 Y288 N290 Y296 Y186 Y285 N287 Y293 P08572 HGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMGTGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMAPGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 6mpx A 1.90 BS05 CL A 5 A74 S75 R76 N77 D78 G178 A71 S72 R73 N74 D75 G175 P08572 HGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMGTGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMAPGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 6mq3 A 3.57 BS01 J22 A 1 A198 L201 F202 L204 E205 Y302 Y314 T316 V360 K364 I374 N376 R477 A479 A156 L159 F160 L162 E163 Y260 Y272 T274 V318 K322 I332 N334 R435 A437 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6mq3 B 3.57 BS01 J22 B 1 A198 L201 E205 Y302 Y314 T316 V360 K364 N376 R477 A479 A156 L159 E163 Y260 Y272 T274 V318 K322 N334 R435 A437 3.4.24.56 P14735 NNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSNPINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6mwh A 2.20 BS01 K5D A 1 G38 L39 L40 Y47 A50 Y56 W60 D73 T75 V76 C79 W88 F101 A105 L110 A127 S129 G32 L33 L34 Y41 A44 Y50 W54 D67 T69 V70 C73 W82 F95 A99 L104 A121 S123 A0A0H2Z901 FLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mwh B 2.20 BS01 K5D B 1 G38 L40 Y56 D73 T75 V76 W88 A105 A127 S129 G32 L34 Y42 D59 T61 V62 W74 A91 A113 S115 A0A0H2Z901 FLELERSSGKLEWSAILQKMASDLGFSKILFGLLPAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mwl A 1.50 BS01 K5G A 1 G32 L33 L34 Y41 I46 Y50 W54 D67 T69 W82 F95 A99 T109 G120 A121 S123 G33 L34 L35 Y42 I47 Y51 W55 D68 T70 W83 F96 A100 T110 G121 A122 S124 A0A0H2Z901 GFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mwl B 1.50 BS01 K5G B 1 G32 L33 L34 Y50 W54 D67 T69 W82 Y87 F95 A99 T109 G120 A121 S123 G32 L33 L34 Y50 W54 D67 T69 W82 Y87 F95 A99 T109 G120 A121 S123 A0A0H2Z901 FLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mww A 2.76 BS01 K5J A 1 G38 L39 L40 Y47 A50 Y56 W60 Y64 D73 T75 V76 C79 W88 Y93 F101 A105 L110 T115 L125 G126 A127 S129 G32 L33 L34 Y41 A44 Y50 W54 Y58 D67 T69 V70 C73 W82 Y87 F95 A99 L104 T109 L119 G120 A121 S123 A0A0H2Z901 FLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFE 6mwz A 1.66 BS01 III M 1 H78 Q81 L84 P85 I86 F87 I92 L148 W152 H73 Q76 L79 P80 I81 F82 I87 L143 W147 A0A0H2Z901 GFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPVVSHCTQSVLPIFWEPSIFQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGWLSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mwz A 1.66 BS02 K5M A 1 L36 I52 Y56 W60 R61 Y64 D73 W88 F101 F102 A105 L110 W127 S129 L31 I47 Y51 W55 R56 Y59 D68 W83 F96 F97 A100 L105 W122 S124 A0A0H2Z901 GFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPVVSHCTQSVLPIFWEPSIFQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGWLSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mwz B 1.66 BS01 III M 1 E11 Y157 E5 Y145 A0A0H2Z901 FLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKNAFIVGNYPAAWREHYDRAGYARVDPVVSHCTQSVLPIFWEPSIFQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGWLSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6mwz B 1.66 BS02 K5M B 1 L36 Y56 W60 R61 Y64 D65 D73 V75 W88 F101 A105 L110 W127 S129 L30 Y44 W48 R49 Y52 D53 D61 V63 W76 F89 A93 L98 W115 S117 A0A0H2Z901 FLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKNAFIVGNYPAAWREHYDRAGYARVDPVVSHCTQSVLPIFWEPSIFQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGWLSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAF 6n9i A 1.60 BS01 CO A 1 H118 H120 H123 H198 D220 H111 H113 H116 H191 D213 A0A023DFE8 30864300 ARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6n9i A 1.60 BS02 FE A 1 D122 H123 D220 H266 D115 H116 D213 H259 A0A023DFE8 30864300 ARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6n9q P 2.35 BS02 HL4 P 1 M20 M22 W26 F48 F87 H120 D122 A157 H198 D220 Y223 H266 M14 M16 W20 F42 F81 H114 D116 A151 H192 D214 Y217 H260 A0A023DFE8 30864300 KARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6n9q D 2.35 BS02 HL4 D 1 M20 M22 F48 H120 D122 A157 H198 D220 Y223 H266 M14 M16 F42 H114 D116 A151 H192 D214 Y217 H260 A0A023DFE8 30864300 KARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6n9r A 1.75 BS03 OHN A 1 M20 M22 W26 F48 M86 F87 H120 D122 E155 G156 A157 H198 D220 Y223 I237 H266 M13 M15 W19 F41 M79 F80 H113 D115 E148 G149 A150 H191 D213 Y216 I230 H259 A0A023DFE8 30864300 ARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6n9r P 1.75 BS03 OHN P 1 M20 M22 W26 F48 M86 F87 H120 D122 A157 H198 D220 Y223 I237 H266 M13 M15 W19 F41 M79 F80 H113 D115 A150 H191 D213 Y216 I230 H259 A0A023DFE8 30864300 ARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6n9r X 1.75 BS03 OHN X 1 M22 W26 F48 F87 H120 D122 G156 A157 H198 D220 Y223 I237 H266 M15 W19 F41 F80 H113 D115 G149 A150 H191 D213 Y216 I230 H259 A0A023DFE8 30864300 ARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE 6nfj A 3.19 BS01 III C 1 F379 K380 L394 W419 F420 T421 D422 M435 F849 L850 Q851 F303 K304 L318 W343 F344 T345 D346 M359 F725 L726 Q727 Q86Z14 FSGDGRAIWSDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPQRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGESTPDVQGQFPCDFSWGVTESVLKPCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGQLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDINDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFP 6nfj A 3.19 BS02 III C 2 Y643 E693 H743 F826 F931 F942 Y524 E574 H619 F702 F807 F818 Q86Z14 FSGDGRAIWSDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPQRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGESTPDVQGQFPCDFSWGVTESVLKPCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGQLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDINDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFP 6nfj D 3.19 BS01 III F 1 V392 L394 W419 F420 D422 M435 F849 L850 Q851 V321 L323 W348 F349 D351 M364 F727 L728 Q729 Q86Z14 FSGDGRAIWSDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPQRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGTPDVQGQFPCDFSWGVTESVLKPCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGQLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFP 6nfj D 3.19 BS02 III F 2 Y643 T645 F826 F931 F942 Y527 T529 F704 F809 F820 Q86Z14 FSGDGRAIWSDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPQRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGTPDVQGQFPCDFSWGVTESVLKPCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGQLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFP 6nuw F 4.25 BS01 III U 1 I199 K202 L206 I210 K213 K217 I38 K41 L45 I49 K52 K56 P53298 30762520 ILRLLETNTVSALDSVFEKYEKEMNQMTHGDNNEVKRIYSKKERLLEIILTKIKKKLRQAKFPDIEYIYSKRQFIQNRYSQELQNNERLEAILSREQNLLEETRKLCMNLKTNNKKRLTEKLIQKDVTFRNDSHELNLMLNDPIKSTADVRLDKEEVLSLLPSLKEYTKKSKELKETMGQMISDSHEEEI 6o62 A 1.88 BS01 GDP A 1 D22 G24 V25 G26 K27 S28 C29 N40 N127 K128 D130 S157 A158 K159 D14 G16 V17 G18 K19 S20 C21 N32 N112 K113 D115 S142 A143 K144 P0CY31 RAYDMIMKLLLVGDSGVGKSCLLLRFVEDKFNGIDFKIRTIESKGKRIKLQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTDSRSFENVENWFQTVTQHANEDAQIFLVGNKCDDEVNRQVSKEQGQELAAKLNVPFLEASAKSNENVDSIFYELASIIQEKHVEENI 6o6q A 2.70 BS01 AMP A 1 L49 R51 G52 V57 V70 I99 E118 H119 I120 H164 M167 I178 D179 L46 R48 G49 V54 V67 I96 E111 H112 I113 H157 M160 I171 D172 A0A1D8PUA2 HRHNTVQSVSRVYADVLSTKPQSYWDYDDLNIKWNPQENYEILRKLGRGKYSEVFLGIDLEKREKVVIKVLKPVKRKKIKREISILKNLVDGPNIIAMLDVVRETPGLIFEHINNIDFRSLYPTFTDYDIRFYMYELLKALDYSHSMGIMHRDVKPHNVMIDHDKKLLRLIDWGLAEYYHPGTEYNVRVASRYFKGPELLVDYRLYDYSLDMWSFGCMLASMVFMKEPFFHGKSNTDQLVQIVRVLGSKNFKKYLEKYNISLGEEYEDIGYYNKRQWVRFMNENNKDLVSQEFLDLIDRLLRYDHQERLTAKEAMKHAYFDPIRVA 6o6q B 2.70 BS01 AMP B 1 L49 V57 V70 E118 H119 I120 H164 M167 L45 V53 V66 E110 H111 I112 H156 M159 A0A1D8PUA2 RHNTVQSVSRVYADVLSTKPQSYWDYDDLNIKWNPQENYEILRKLGRGKYSEVFLGIDLEKREKVVIKVLKPVKRKKIKREISILKNLVDGPNIIAMLDVVRKTPGLIFEHINNIDFRSLYPTFTDYDIRFYMYELLKALDYSHSMGIMHRDVKPHNVMIDHDKKLLRLIDWGLAEYYHPGTEYNVRVASRYFKGPELLVDYRLYDYSLDMWSFGCMLASMVFMKEPFFHGKSNTDQLVQIVRVLGSKNFKKYLEKYNISLGEEYEDIGYYNKRQWVRFMNENNKDLVSQEFLDLIDRLLRYDHQERLTAKEAMKHAYFDPIRVA 6o8i A 1.42 BS01 LTJ A 1 L408 G409 V416 A428 T474 E475 Y476 M477 A478 G480 C481 L483 N484 R525 L528 V546 L547 L18 G19 V26 A38 T76 E77 Y78 M79 A80 G82 C83 L85 N86 R127 L130 V148 L149 2.7.10.2 Q06187 30893553 GYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 6o9a A 2.33 BS01 3HB A 1 I22 F24 N26 V27 N63 V64 S65 V84 M115 A205 I6 F8 N10 V11 N47 V48 S49 V68 M99 A189 4.2.1.151 Q9RXE3 30855131 YRAGWIHFTNVAPILDSLELPPGVTAITGVPTQMNAALLSGEVDIANVSAVEFIRHADTLAALPDFSVAVLGPVYSVNLFHTCPLPELRRVALTSQSAMSVALLEVLLRQKGLSPVLERAEGTAESLLAAGYDGVLRIGDDALREWYGVVGPLTPERTMTSLPHTGRGITVTDLAQEWFDLTGHPFTFAVWAYRKDNPPPAALLQAMREARRRGIGHLAEVSQRHAEKLGLPERVVQHYLWNFRYHLEAPDRLGLREFADLAVPGHAELTF 6o9a B 2.33 BS01 3HB B 1 F24 N26 V27 N63 V64 S65 A205 F8 N10 V11 N47 V48 S49 A189 4.2.1.151 Q9RXE3 30855131 YRAGWIHFTNVAPILDSLELPPGVTAITGVPTQMNAALLSGEVDIANVSAVEFIRHADTLAALPDFSVAVLGPVYSVNLFHTCPLPELRRVALTSQSAMSVALLEVLLRQKGLSPVLERAEGTAESLLAAGYDGVLRIGDDALREWYGVVGPLTPERTMTSLPHTGRGITVTDLAQEWFDLTGHPFTFAVWAYRKDNPPPAALLQAMREARRRGIGHLAEVSQRHAEKLGLPERVVQHYLWNFRYHLEAPDRLGLREFADLAVPGHAELTF 6o9p A 2.10 BS01 BFQ A 1 R279 Y288 T313 D316 D320 I417 L422 R457 N460 R239 Y248 T273 D276 D280 I377 L382 R417 N420 A0A0A0RDR2 WDYDFLQSLGRHEEHVGLAEKLKGEVKSLITGPMEPLAKLEFIDSVRRLGLKYQFETEMKEALANISKDGYDSWWVDNLRATALRFRLLRENGIFVPQDVFERFQNKETGKFKNELCEDVKGLLNLYEASFLGWEGEDILDEARTFSTAQLKNVEGKISSPNLAKIVHHALDLPLHWRAIRYEARWFIDIYEDEEDMNPTLLKYAKLDFNIVQSFHQAEIGRLARWWVGTGLDKLPFARNGLIQSYMYAIGMLFEPHLGEVREMEAKVGALITTIDDVYDVYGTMEELELFTDITERWDINRVDQLPRNIRMPLLTMFNTSNDIGYWALKERGFNGIPYTAKVWADQLKSYTKEAKWFHEGHKPTLEEYLENALVSIGFPNLLVTSYLLTVDNPTKEKLDYVDSLPLFVRASCILCRIINDLGTRGDNLKSIQCYMNETGASQEVAREHIEGLVRMWWKRLNKCLFEPSPFTEPFLSFTINVVRGSHFFYQSWTKNQGMSVLIHPITL 6o9p A 2.10 BS02 MG A 1 D316 D320 D276 D280 A0A0A0RDR2 WDYDFLQSLGRHEEHVGLAEKLKGEVKSLITGPMEPLAKLEFIDSVRRLGLKYQFETEMKEALANISKDGYDSWWVDNLRATALRFRLLRENGIFVPQDVFERFQNKETGKFKNELCEDVKGLLNLYEASFLGWEGEDILDEARTFSTAQLKNVEGKISSPNLAKIVHHALDLPLHWRAIRYEARWFIDIYEDEEDMNPTLLKYAKLDFNIVQSFHQAEIGRLARWWVGTGLDKLPFARNGLIQSYMYAIGMLFEPHLGEVREMEAKVGALITTIDDVYDVYGTMEELELFTDITERWDINRVDQLPRNIRMPLLTMFNTSNDIGYWALKERGFNGIPYTAKVWADQLKSYTKEAKWFHEGHKPTLEEYLENALVSIGFPNLLVTSYLLTVDNPTKEKLDYVDSLPLFVRASCILCRIINDLGTRGDNLKSIQCYMNETGASQEVAREHIEGLVRMWWKRLNKCLFEPSPFTEPFLSFTINVVRGSHFFYQSWTKNQGMSVLIHPITL 6qg9 A 2.05 BS01 CA A 1 D304 D307 L309 D311 I313 D260 D263 L265 D267 I269 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDGDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qg9 I 2.05 BS01 CA I 1 D304 D307 L309 A310 D311 I313 D260 D263 L265 A266 D267 I269 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDGDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qg9 J 2.05 BS01 CA J 1 D304 D307 L309 D311 I313 D315 D260 D263 L265 D267 I269 D271 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDGDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFAC 6qga A 2.10 BS01 J1K A 1 S131 G132 S225 E226 L254 A257 W397 R411 F415 S416 F495 H528 C529 S87 G88 S181 E182 L210 A213 W353 R367 F371 S372 F451 H484 C485 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDGDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAP 6qga B 2.10 BS01 J1K B 1 S131 G132 S225 E226 L254 W397 R411 F415 S416 F495 H528 S86 G87 S180 E181 L209 W352 R366 F370 S371 F450 H483 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qga C 2.10 BS01 J1K C 1 M61 V62 P64 R210 M15 V16 P18 R164 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qga E 2.10 BS01 J1K E 1 T82 A83 A86 I149 A150 R155 T37 A38 A41 I104 A105 R110 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qga E 2.10 BS02 J1K E 2 K205 A206 A209 K160 A161 A164 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qga F 2.10 BS02 J1K F 2 V62 P64 A206 R210 V18 P20 A162 R166 3.1.1.102 A0A0K8P8E7 VPLASRAACEALKDGDMVWPNAATVVEVAAWRDAAPATASAAALPEHCEVSGAIAKRTGIDGYPYEIKFRLRMPAEWNGRFFMEGGSGTNGSLSAATGSIGGGQIASALSRNFATIATDGGHDNAVNDNPDALGTVAFGLDPQARLDMGYNSYDQVTQAGKAAVARFYGRAADKSYFIGCSEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAPAAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGLADGIVDNYRACQAAFDPATAANPANGQALQCVGAKTADCLSPVQVTAIKRAMAGPVNSAGTPLYNRWAWDAGMSGLSGTTYNQGWRSWWLGSFNSSANNAQRVSGFSARSWLVDFATPPEPMPMTQVAARMMKFDFDIDPLKIWATSGQFTQSSMDWHGATSTDLAAFRDRGGKMILYHGMSDAAFSALDTADYYERLGAAMPGAAGFARLFLVPGMNHCSGGPGTDRFDMLTPLVAWVERGEAPDQISAWSGTPGYFGVAARTRPLCPYPQIARYKGSGDINTEANFACAAPP 6qtn B 1.90 BS02 JHH B 1 L217 L219 H229 A233 R278 L371 L214 L216 H226 A230 R275 L360 Q6B856 30897704 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 6qtn D 1.90 BS02 JHH D 1 L217 H229 A233 L215 H227 A231 Q6B856 30897704 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6qtn F 1.90 BS01 ACP F 1 I148 Q183 K184 Y185 L186 K198 D200 R202 R222 T241 N242 D318 M320 I330 E331 N333 I126 Q149 K150 Y151 L152 K164 D166 R168 R188 T202 N203 D279 M281 I291 E292 N294 E1BQ43 30897704 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIAGILISSEASELLDFIDEVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSATCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKLHH 6qzo A 2.40 BS01 HEM A 1 N195 Q199 V200 E201 G202 T203 A204 I236 M238 I255 R257 H292 I293 A296 F305 R307 L326 F328 F339 V342 Q343 L346 L352 T356 N173 Q177 V178 E179 G180 T181 A182 I214 M216 I233 R235 H270 I271 A274 F283 R285 L304 F306 F317 V320 Q321 L324 L330 T334 A0A0A0BZU2 AGPGDVVVPCHGEHQAGIVTPPPSFIALVALDLASTSDRASVERLLRVWTVDIERLTTGRPGLADSEPELALVPAALTVTVGFGPGLLTAAGLRHRAPAWLHPLPPFGIDRLDPAWCDGDVVLQVCADDRTTLAHAVRVLTKEAQGLASVRWVQRGFRRSPGISEPDGTSMRNLMGQVEGTANLDPRTDPDLLWHRDGEPGWLTGGTSMVVRRIAMNLDTWDELSRGAREATIGRTLRTGAPLTGRAEHDEPDLEALDDHGRPVIDLEAHIRRARPTQREETFLRRAYNYDEAPPPGRASDSGLLFVTYQRDVDAQFTPVQRRLDAADLLNEWTFPVGSAVFAVPGGWSAGEYVGQRLLEG 6qzo E 2.40 BS01 HEM E 1 N195 M197 Q199 V200 E201 G202 T203 A204 I236 M238 I255 R257 H292 I293 A296 R297 P298 F305 R307 F328 F339 V342 Q343 L346 L352 T356 N173 M175 Q177 V178 E179 G180 T181 A182 I214 M216 I233 R235 H270 I271 A274 R275 P276 F283 R285 F306 F317 V320 Q321 L324 L330 T334 A0A0A0BZU2 AGPGDVVVPCHGEHQAGIVTPPPSFIALVALDLASTSDRASVERLLRVWTVDIERLTTGRPGLADSEPELALVPAALTVTVGFGPGLLTAAGLRHRAPAWLHPLPPFGIDRLDPAWCDGDVVLQVCADDRTTLAHAVRVLTKEAQGLASVRWVQRGFRRSPGISEPDGTSMRNLMGQVEGTANLDPRTDPDLLWHRDGEPGWLTGGTSMVVRRIAMNLDTWDELSRGAREATIGRTLRTGAPLTGRAEHDEPDLEALDDHGRPVIDLEAHIRRARPTQREETFLRRAYNYDEAPPPGRASDSGLLFVTYQRDVDAQFTPVQRRLDAADLLNEWTFPVGSAVFAVPGGWSAGEYVGQRLLEG 6qzo H 2.40 BS01 HEM H 1 N195 Q199 V200 E201 G202 T203 A204 I236 R257 H292 I293 A296 R297 P298 F305 R307 L326 F328 V342 Q343 L346 L352 T356 N173 Q177 V178 E179 G180 T181 A182 I214 R235 H270 I271 A274 R275 P276 F283 R285 L304 F306 V320 Q321 L324 L330 T334 A0A0A0BZU2 AGPGDVVVPCHGEHQAGIVTPPPSFIALVALDLASTSDRASVERLLRVWTVDIERLTTGRPGLADSEPELALVPAALTVTVGFGPGLLTAAGLRHRAPAWLHPLPPFGIDRLDPAWCDGDVVLQVCADDRTTLAHAVRVLTKEAQGLASVRWVQRGFRRSPGISEPDGTSMRNLMGQVEGTANLDPRTDPDLLWHRDGEPGWLTGGTSMVVRRIAMNLDTWDELSRGAREATIGRTLRTGAPLTGRAEHDEPDLEALDDHGRPVIDLEAHIRRARPTQREETFLRRAYNYDEAPPPGRASDSGLLFVTYQRDVDAQFTPVQRRLDAADLLNEWTFPVGSAVFAVPGGWSAGEYVGQRLLEG 6r3k A 2.20 BS01 JQT B 1 I54 Y56 M115 I116 A121 D122 Y123 K124 R125 I37 Y39 M98 I99 A104 D105 Y106 K107 R108 Q9NZQ7 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHH 6r3k B 2.20 BS01 JQT B 1 I54 Y56 Q66 V68 M115 I116 A121 D122 I37 Y39 Q49 V51 M98 I99 A104 D105 Q9NZQ7 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHH 6r3k D 2.20 BS01 JQT D 1 F19 T20 I54 Y56 M115 I116 S117 A121 D122 Y123 K124 R125 F2 T3 I37 Y39 M98 I99 S100 A104 D105 Y106 K107 R108 Q9NZQ7 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYAAALEHHHHH