5od1 A 1.34 BS01 ZN A 1 H35 H61 H65 H35 H61 H65 GSPLAQQIKNTLTFIGQANAAGRMDEVRTLQQNLHPLWAEYFQQTEGSGGSPLAQQIQYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQS 5od1 A 1.34 BS02 9RQ A 1 R28 Q31 Q32 L34 H35 W38 H61 I64 H65 R68 T83 M87 R28 Q31 Q32 L34 H35 W38 H61 I64 H65 R68 T83 M87 GSPLAQQIKNTLTFIGQANAAGRMDEVRTLQQNLHPLWAEYFQQTEGSGGSPLAQQIQYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQS 5od9 A 1.13 BS01 ZN A 1 H1039 E1058 H1061 H39 E58 H61 GSPLAQQIKNTLTFIGQANAAGRMDEVRTLQENLHPLWHEYFQQTEGSGGSPLAQQIEYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQSD 5od9 A 1.13 BS03 MG A 1 E1089 Q1092 E89 Q92 GSPLAQQIKNTLTFIGQANAAGRMDEVRTLQENLHPLWHEYFQQTEGSGGSPLAQQIEYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQSD 5od9 A 1.13 BS04 9RW A 1 G1060 R1078 L1079 N1082 G60 R78 L79 N82 GSPLAQQIKNTLTFIGQANAAGRMDEVRTLQENLHPLWHEYFQQTEGSGGSPLAQQIEYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQSD 5od9 B 1.13 BS01 ZN A 3 H2035 H2039 H34 H38 SPLAQQIKNTLTFIGQANAAGRMDEVRTLQENLHPLWHEYFQQTESPLAQQIEYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQ 5od9 B 1.13 BS02 ZN A 4 E2032 H2035 E31 H34 SPLAQQIKNTLTFIGQANAAGRMDEVRTLQENLHPLWHEYFQQTESPLAQQIEYGHVLIHQARAAGRMDEVRRLSENTLQLMKEYFQQ 5w1x B 3.37 BS01 IDS B 1 Y49 K64 Q226 S227 Y30 K45 Q207 S208 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x B 3.37 BS02 IDS C 1 S211 Q226 S192 Q207 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x C 3.37 BS02 JHM C 1 T95 T383 T76 T364 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x D 3.37 BS02 JHM D 2 T280 G281 T261 G262 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x E 3.37 BS02 JHM E 1 G172 T173 A174 G153 T154 A155 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x F 3.37 BS02 JHM F 2 R178 P179 L180 S181 R159 P160 L161 S162 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x F 3.37 BS06 IDS F 2 S175 R178 C185 P186 P187 S156 R159 C166 P167 P168 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x J 3.37 BS01 IDS F 3 N58 K59 Q60 N39 K40 Q41 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5w1x N 3.37 BS02 JHM N 2 P351 V352 P353 P332 V333 P334 Q5G244 21115492 AVVNTDDYVTRTSIFYHAGSSRLLTVGDPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTASKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIQSMNSSILEDWNNKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAG 5yl1 A 3.12 BS01 CA A 1 E118 T196 Q248 N250 E53 T131 Q183 N185 A5H7Q8 ISRLGPDSDFLTSVVAKASTSIVTPADRILVKQPLSASSFPGTRITGLSSYWERYKWLSAVARYVPAVPNTVACQFVMYIDTDPLDDPSNISDDNQIVRQAVSQAGSNQFNFNTSKTVPLIVRADNQYYYTGVDKQNLRFSLQGILYIIQVTDLINFNGELITQDLTCGSLFLDWLVNFSIPQIN 5yl1 A 3.12 BS02 CA A 2 E118 Q248 E53 Q183 A5H7Q8 ISRLGPDSDFLTSVVAKASTSIVTPADRILVKQPLSASSFPGTRITGLSSYWERYKWLSAVARYVPAVPNTVACQFVMYIDTDPLDDPSNISDDNQIVRQAVSQAGSNQFNFNTSKTVPLIVRADNQYYYTGVDKQNLRFSLQGILYIIQVTDLINFNGELITQDLTCGSLFLDWLVNFSIPQIN 5yxf A 1.61 BS03 MET A 1 Y97 L105 H114 D131 T133 D142 H205 F211 H212 E238 W255 E269 Y94 L102 H111 D128 T130 D139 H202 F208 H209 E235 W252 E266 3.4.11.18 A5U6L5 RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCLTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTAL 5yxn C 2.03 BS01 III I 1 M6 Y8 F10 M46 E64 K67 V68 H71 T74 D78 Y85 R98 Y100 Y117 T144 K147 W148 V153 Q156 Y160 W168 Y172 M5 Y7 F9 M45 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 K146 W147 V152 Q155 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 5yxu A 2.70 BS01 III I 1 S29 D32 E97 D98 S28 D31 E96 D97 AQTVTQSQPEMSVQEAETVTLSCTYDTSENDYILFWYKQPPSRQMILVIRQEAYKQQNATENRFSVNFQKAAKSFSLKISDSQLGDAAMYFCAYGEDDKIIFGKGTRLHILPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNN 5yxu B 2.70 BS01 III I 1 D31 S98 D31 S98 AEADIYQTPRYLVIGTGKKITLECSQTMGHDKMYWYQQDPGMELHLIHYSYGVNSTEKGDLSSESTVSRIRTEHFPLTLESARPSHTSQYLCASRRGSAELYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAA 5yxu C 2.70 BS01 III I 1 Y8 F10 M46 E64 K67 V68 H71 T74 D78 T81 Y85 R98 Y100 Y117 T144 K147 W148 V153 Q156 L157 Y160 T164 W168 Y172 Y7 F9 M45 E63 K66 V67 H70 T73 D77 T80 Y84 R97 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 5yy9 A 2.65 BS01 III C 1 D142 D145 M148 F152 E153 Y188 D190 Y191 N194 M224 N226 R235 G236 W238 E276 F278 D6 D9 M12 F16 E17 Y43 D45 Y46 N49 M79 N81 R90 G91 W93 E130 F132 2.3.2.27 Q96T88 VNEYVDARDTNMGAWFEAQVVRVTRKAPSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDSLNDCRIIFVDEVFKIERP 5yy9 B 2.65 BS01 III D 1 D142 D145 M148 F152 E153 Y188 D190 Y191 N194 M224 N226 R235 G236 F237 W238 E276 D18 D21 M24 F28 E29 Y45 D47 Y48 N51 M81 N83 R92 G93 F94 W95 E130 2.3.2.27 Q96T88 DMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLSLNDCRIIFVDEVFKIERPG 5yym A 2.20 BS01 ARG A 1 D118 A121 S135 H158 Y336 I337 D338 D126 A129 S143 H166 Y340 I341 D342 6.1.1.19 P11875 HHHHHGGAMNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENALADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM 5yym B 2.20 BS01 ARG B 1 D118 A121 N123 H158 G160 E258 I337 D125 A128 N130 H165 G167 E256 I335 6.1.1.19 P11875 HHHHGGAMNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQELEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM 5z19 A 2.50 BS01 SJ5 A 1 D167 H335 F369 E418 Y474 Y478 E512 W557 R570 N574 K576 D166 H331 F365 E414 Y470 Y474 E508 W553 R566 N570 K572 Q6W7J7 LEYSELYPIQNEYRMMQSLDGMWKFQFDPEEIGKKSGWENGLPAPVSMPVPSSFADFFTDHKERDYCGDFWYETEFYLPAEWRNKKIWLRFGSITHRGTVYCNGMEITSHEGGFLPVLADISTVAKPGQVNQVVVKINNELNETSLPCGATKILNNGRKLAKPYFDFFNYSGLQRSVWVIALPEESVKDYSVDYELCGTDALVKYEVVTTGEHPVIVRLLDAEGELVAETEGKEGILQVANARLWEVRNAYLYQIVILITDVLDEYREKIGIRTVRIEGTKILLNDRPVYLKGFGKHEDFPILGRGFHWGIVKRDFECLKWTNANCFRTSHYPYAEEWYQFADEEGFLIIDEVPAVGMMRSTRNFVAAGSGNYTYFFEALTVPELLKSHIADTEEMITRDKNHPSVIAWSLFNEPETITDYAYEYFKEVFAAAETYDFQSRPMTGAFEKNSKPELCKCYPLCDFICLNRYYGWYISGGPEIEEAEELFRDEMDRWKAKELNVPFVFTEFGTDTMAGLHKLPSIMWSEEYQKEYLEMNFRVFDSYEFVQGELAWNFADFQTTEGIMRVDGNHKGVFTRDRQPKAAAVVFKDRWE 5z1a A 1.86 BS01 SJ5 A 1 D166 H359 E429 Y479 Y483 E510 W562 F567 R572 N581 K583 D131 H324 E394 Y444 Y448 E475 W527 F532 R537 N546 K548 Q5LIC7 SLRQDILLNNNWNFRFSHQVQGDTRRVDLPHTWNAQDALAGKIDYKRGIGNYEKALYIRPEWKGKRLFLRFDGVNSIADVFINRKHIGEHRGGYGAFIFEITDLVKYGEKNSVLVRANNGEQLDIMPLVGDFNFYGGIYRDVHLLITDETCISPLDYASPGVYLVQEVVSPQEAKVCAKVNLSNRAADGTAELQVLVTDGTKVICKESRNVSLKQGADILEQLPLLIQKPRLWNGCEDPFMYQVSISLHKDGKQIDSVTQPLGLRYYHTDPDKGFFLNGKHLPLHGVCRHQDRAEVGNALRPQHHEEDVALMREMGVNAIRLAHYPQATYMYDLMDKHGIVTWAEIPFVGPGGYADKGFVDQASFRENGKQQLIELIRQHYNHPSICFWGLFNELKEVGDNPVEYVKELNALAKQEDPTRPTTSASNQDGNLNFITENIAWNRYDGWYGSTPKTLATFLDRTHKKHPELRIGISEYGAGASIYHQQDSLKQPSASGWWHPENWQTYYHMENWKIIAERPFVWGTFVWNMFDFGAAHRTEGDRPGINDKGLVTFDRKVRKDAFYFYKANWNKQEPMIYLAEKRCRLRYQPEQTFMAFTTAPEAELFVNGVSCGKQKADTYSTVVWKNVKLTSGENIIRVTTPGKKPLTDEVTVEYK 5z1b A 1.45 BS01 BDP A 1 M153 D179 H413 N478 N537 Y539 Y543 E574 W619 R632 N636 K638 M155 D181 H373 N438 N497 Y499 Y503 E534 W579 R592 N596 K598 3.2.1.31 E0QAF3 NGMLYPQSNDSRIVFPLDGVWDFRTAGEDSYPAEWADAPLPEPLPMAVPGSYNDQNDELNLRAHYGWVVYQRSFAVPSRLVAGQRMILRFDAATHAADVYLNGQLLGSHFGGFLPFEFDVTSALHAGENLLTVAVDNRIGSSTLPVGNDAGTAFMGSDNANVPAVAEAKKHARRQNLPNFDFFNFAGLNRHVELYTTPADAYIADIAITTERLDHIAGDACTAANALIAYDVTFGGDGRQVRISILDGEGTVVAGVTADIERTAKASGEIAIRDAKLWNPGAAYLYTAVAELLPEGGAESSSRIIDAYRQTFGIRTVEVSGTTFLINGKPFYFKGFGKHEDSYFHGRGTDDVLNVKDVSLIHWLHANSFRTSHYPYAESMYDLCDREGIVIIDEVPAVGMSWLQYANPLVAERHREAIRGMIARDKNHPCIVMWSIANAPGLDGDGERPRQAYDYFRPLYELAHASDPQNRPVTLVCCQNDYTTDITERTMDVVCINRYYGWYNLSGDLDAACHALNIELDFWENIGKPVMFTEYGADTIEGIHGTHGEMFSEEFQRDYYARINAEIDKRPWFIGEQLWNFADFATFQGIIRVEGNRKGILTRDRQPKMAAHWLRERWAGIPDYGYK 5z1b A 1.45 BS02 SE2 A 1 M153 C518 Q519 N537 Y539 Y543 M155 C478 Q479 N497 Y499 Y503 3.2.1.31 E0QAF3 NGMLYPQSNDSRIVFPLDGVWDFRTAGEDSYPAEWADAPLPEPLPMAVPGSYNDQNDELNLRAHYGWVVYQRSFAVPSRLVAGQRMILRFDAATHAADVYLNGQLLGSHFGGFLPFEFDVTSALHAGENLLTVAVDNRIGSSTLPVGNDAGTAFMGSDNANVPAVAEAKKHARRQNLPNFDFFNFAGLNRHVELYTTPADAYIADIAITTERLDHIAGDACTAANALIAYDVTFGGDGRQVRISILDGEGTVVAGVTADIERTAKASGEIAIRDAKLWNPGAAYLYTAVAELLPEGGAESSSRIIDAYRQTFGIRTVEVSGTTFLINGKPFYFKGFGKHEDSYFHGRGTDDVLNVKDVSLIHWLHANSFRTSHYPYAESMYDLCDREGIVIIDEVPAVGMSWLQYANPLVAERHREAIRGMIARDKNHPCIVMWSIANAPGLDGDGERPRQAYDYFRPLYELAHASDPQNRPVTLVCCQNDYTTDITERTMDVVCINRYYGWYNLSGDLDAACHALNIELDFWENIGKPVMFTEYGADTIEGIHGTHGEMFSEEFQRDYYARINAEIDKRPWFIGEQLWNFADFATFQGIIRVEGNRKGILTRDRQPKMAAHWLRERWAGIPDYGYK 5z36 A BS01 969 A 1 V8 R9 K10 S11 V12 V117 L119 P141 E145 T146 L147 F150 V8 R9 K10 S11 V12 V117 L119 P141 E145 T146 L147 F150 A0A0K1H313 30151879 MPEEIPDVRKSVVVAASVEHCFEVFTSRPADWWPPSHVLVKKERAGLAFEPFVGGRYYEWDIDGTEIVWGRILEWDPPHRLAMTWRIDGHWQSVPDDDRASEIEVDFVPNGSGGTRVELAHVKLHRHGDGAWNIHKALDGPSPGETLARFANVI 5z4h A 2.00 BS01 A8K A 1 V43 N46 A47 V71 Q72 D73 I78 A91 I94 M95 V120 L132 T165 V167 V28 N31 A32 V56 Q57 D58 I63 A76 I79 M80 V88 L100 T133 V135 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z4h A 2.00 BS02 AX7 A 1 R20 H147 E174 R5 H115 E142 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z4o A 1.73 BS01 HX8 A 1 V43 N46 A47 Q72 D73 I78 I94 M95 V120 T165 V167 V28 N31 A32 Q57 D58 I63 I79 M80 V86 T131 V133 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z4o B 1.73 BS01 HX8 B 1 V43 N46 A47 D73 I78 I94 M95 V120 L132 T165 V167 V28 N31 A32 D58 I63 I79 M80 V87 L99 T132 V134 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEG 5z9b A 2.10 BS01 HX3 A 1 N46 A47 E50 V71 D73 I78 I94 M95 V120 T165 V167 N31 A32 E35 V56 D58 I63 I79 M80 V88 T133 V135 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z9e A 1.80 BS01 27K A 1 V43 N46 E50 I78 P79 I94 V120 T165 V167 V28 N31 E35 I63 P64 I79 V87 T132 V134 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z9e B 1.80 BS01 27K B 1 V43 N46 E50 I78 P79 I94 V120 V167 V28 N31 E35 I63 P64 I79 V87 V134 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEG 5z9f A 1.76 BS01 0R0 A 1 V43 N46 E50 V71 I78 V120 T165 V167 V28 N31 E35 V56 I63 V87 T132 V134 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5z9f B 1.76 BS01 0R0 B 1 V43 N46 E50 I78 V120 T165 V167 V28 N31 E35 I63 V87 T132 V134 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEG 5z9l A 1.60 BS01 8H8 A 1 V43 N46 A47 E50 V71 Q72 D73 I78 V120 T165 V167 V28 N31 A32 E35 V56 Q57 D58 I63 V86 T131 V133 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYE 5z9m A 2.74 BS01 BZ2 A 1 E50 R76 G77 P79 R136 E35 R61 G62 P64 R103 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEG 5z9m B 2.74 BS01 BZ2 B 1 E50 R76 G77 I78 P79 R136 E35 R61 G62 I63 P64 R104 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEG 5z9p A 1.45 BS01 AX7 A 1 N54 D81 I86 I102 L103 N35 D62 I67 I83 L84 5.99.1.3 P0A0K8 30429968 QVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTDNGRGIPVDIQEKMGRPAVEVILTSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYE 5z9q A 1.80 BS01 HX4 A 1 N46 A47 V71 D73 I78 I94 V120 T165 N31 A32 V49 D51 I56 I72 V80 T125 5.99.1.3 P0AES6 30429968 LDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY 5zve B 2.18 BS01 SAH B 1 A209 A210 A211 P212 G213 G214 K215 D233 K234 R238 M259 D260 A261 D277 P279 Y304 F308 A205 A206 A207 P208 G209 G210 K211 D229 K230 R234 M255 D256 A257 D273 P275 Y300 F304 O57712 YLEAFPKELREYYKNLFGKEEANKIMKKLREPVEHYYIRVNTLKISREKLIGELKKEGLKPLRSPYLPEGLYFVREGPNFSDDFEPKLPVVVANKYAAESVYQGAMLYAPGVLKADKNIKEGDEVQIRDPKGLLVGIGIARMDYKEMTEATRGLAVEVTLPKFKLPSLSELKAFEKGYFYPQGLPSMVTARVLEPKEDDVIIDMAAAPGGKTTHIAQLLENKGEIIAIDKSKNRLRKMEENIKRLGVKNVKLVQMDARKLPDLGIKADKILLDAPCTALGVRPKLWEERTLKHIEATARYQRAFIWAAIKSLRRGGVLVYSTCTLSYEENEGNVKFMIRKGMKLEEQSIFIGSPGIGMNKVQRFYPHKHLTQGFFIAKLRKVKD 5zvh A 2.50 BS01 SFG A 1 M208 A209 A210 A211 P212 G213 G214 K215 D233 K234 S235 R238 M259 D260 A261 D277 Y304 F308 M204 A205 A206 A207 P208 G209 G210 K211 D229 K230 S231 R234 M255 D256 A257 D273 Y300 F304 O57712 YLEAFPKELREYYKNLFGKEEANKIMKKLREPVEHYYIRVNTLKISREKLIGELKKEGLKPLRSPYLPEGLYFVREGPNFSDDFEPKLPVVVANKYAAESVYQGAMLYAPGVLKADKNIKEGDEVQIRDPKGLLVGIGIARMDYKEMTEATRGLAVEVTLPKFKLPSLSELKAFEKGYFYPQGLPSMVTARVLEPKEDDVIIDMAAAPGGKTTHIAQLLENKGEIIAIDKSKNRLRKMEENIKRLGVKNVKLVQMDARKLPDLGIKADKILLDAPCTALGVRPKLWEERTLKHIEATARYQRAFIWAAIKSLRRGGVLVYSTCTLSYEENEGNVKFMIRKGMKLEEQSIFIGSPGIGMNKVQRFYPHKHLTQGFFIAKLRKVKD 6a22 A 2.55 BS01 III B 1 H322 Q329 V332 K336 F341 Q349 I350 L353 K354 E481 Q487 H60 Q67 V70 K74 F79 Q87 I88 L91 K92 E219 Q225 P51449 30478402 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 A 2.55 BS02 9P6 A 1 L287 W317 C320 H323 M365 V376 F377 F378 E379 F388 L391 I400 F401 C476 L25 W55 C58 H61 M103 V114 F115 F116 E117 F126 L129 I138 F139 C214 P51449 30478402 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 C 2.55 BS01 III D 1 V332 K336 I350 L353 K354 M358 Q484 V67 K71 I85 L88 K89 M93 Q219 P51449 30478402 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 C 2.55 BS02 9P6 C 1 L287 W317 C320 H323 M365 C366 V376 F377 F378 E379 F388 L391 I400 F401 S404 L22 W52 C55 H58 M100 C101 V111 F112 F113 E114 F123 L126 I135 F136 S139 P51449 30478402 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 E 2.55 BS01 III F 1 T325 V332 K336 Q349 I350 L353 K354 T60 V67 K71 Q84 I85 L88 K89 P51449 30478402 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 E 2.55 BS02 9P6 E 1 Q286 C320 H323 M365 C366 A368 V376 F377 F378 E379 F388 L391 I400 F401 S404 C476 Q21 C55 H58 M100 C101 A103 V111 F112 F113 E114 F123 L126 I135 F136 S139 C211 P51449 30478402 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 G 2.55 BS01 III H 1 T325 V332 K336 I350 L353 K354 S477 V480 E481 Q484 T60 V67 K71 I85 L88 K89 S212 V215 E216 Q219 P51449 30478402 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6a22 G 2.55 BS02 9P6 G 1 Q286 L292 C320 H323 M365 V376 F377 F378 E379 F388 L391 I400 F401 S404 C476 Q21 L27 C55 H58 M100 V111 F112 F113 E114 F123 L126 I135 F136 S139 C211 P51449 30478402 SLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPAGKLASLCSQHVERLQIFQHLHPIV 6aaf A 2.20 BS01 III B 1 F5 F9 K13 E17 I21 Y25 R28 I32 K46 K48 Y49 P52 D54 L55 Q59 Y62 V63 R67 F104 F4 F8 K12 E16 I20 Y24 R27 I31 K45 K47 Y48 P51 D53 L54 Q58 Y61 V62 R66 F103 O94272 30451685 RSQFKDDFSFEKRKTESQRIREKYPDRIPVICEKVDKSDIAAIDKKKYLVPSDLTVGQFVYVIRKRIKLSPEKAIFIFIDEILPPTAALMSTIYEEHKSEDGFLYITYSGEN 6aem A 1.27 BS01 CA A 1 N3 Q4 D27 D29 D68 N2 Q3 D26 D28 D67 30268503 ENQAPVANFELKTDGLSVSAFNYSHDEDGELVSYAWDFGNGQMSSEMAPSWSYTRAGQYTVSLTVTDDKGATNTTTRTTQVEVP 6aem A 1.27 BS02 ZN A 1 H26 E28 H25 E27 30268503 ENQAPVANFELKTDGLSVSAFNYSHDEDGELVSYAWDFGNGQMSSEMAPSWSYTRAGQYTVSLTVTDDKGATNTTTRTTQVEVP 6afr A 2.00 BS01 9E3 A 1 W81 P82 V87 L92 Y139 N140 W40 P41 V46 L51 Y98 N99 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 6bth A 1.35 BS01 ECB A 1 F16 Y19 M20 L23 I25 A33 Q38 K40 T51 T53 R58 Y60 V62 L77 W106 Q108 F17 Y20 M21 L24 I26 A34 Q39 K41 T52 T54 R59 Y61 V63 L78 W107 Q109 P50120 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKKL 6bti A 1.45 BS01 E7Y A 1 F16 Y19 M20 L23 I25 T51 T53 R58 Y60 V62 L77 W106 L119 F17 Y20 M21 L24 I26 T52 T54 R59 Y61 V63 L78 W107 L120 P50120 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKKLV 6bti B 1.45 BS01 E7Y B 1 F16 Y19 M20 L23 I25 A33 Q38 K40 T53 F57 R58 Y60 L77 W106 Q108 F17 Y20 M21 L24 I26 A34 Q39 K41 T54 F58 R59 Y61 L78 W107 Q109 P50120 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKKLVP 6bu5 A 2.40 BS01 MN A 1 A53 Y54 D56 N59 M230 A15 Y16 D18 N21 M192 Q9RTP8 RILPFLGPAVIASIAYMDPGNFATNIEGGARYGYSLLWVILAANLMAMVIQNLSANLGIASGRNLPELIRERWPRPLVWFYWIQAELVAMATDLAEFLGAALAIQLLTGLPMFWGAVVTGVVTFWLLNLQKRGTRPLELAVGAFVLMIGVAYLVQVVLARPDLAAVGAGFVPRLQGPGSAYLAVWIIGATVMPHVIYLHSALTQGRIQTDTTEEKRRLVRLNRVDVIAAMGLAGLINMSMLAVAAATFHGKNVENAGDLTTAYQTLTPLLGPAASVLFAVALLASGLSSSAVGTMAGDVIMQGFMGFHIPLWLRRLITMLPAFIVILLGMDPSSVLILSQVILCFGVPFALVPLLLFTARRDVMGALVTRRSFTVIGWVIAVIIIALNGYLLWELLGG 6bul A 1.88 BS02 NAP A 1 Y25 G26 S27 Q28 I47 R48 S52 V66 L79 L80 P81 D82 Q85 V88 A106 H107 P129 G131 P132 G133 Y24 G25 S26 Q27 I46 R47 S51 V65 L78 L79 P80 D81 Q84 V87 A105 H106 P128 G130 P131 G132 1.1.1.86 Q2YUF3 TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELRE 6bul A 1.88 BS03 E9G A 1 D190 E194 L198 D189 E193 L197 1.1.1.86 Q2YUF3 TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELRE 6bul A 1.88 BS04 E9J A 1 P132 D190 E194 L198 P131 D189 E193 L197 1.1.1.86 Q2YUF3 TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELRE 6bul A 1.88 BS05 E9G B 1 E230 L233 L237 I250 S251 A254 E229 L232 L236 I249 S250 A253 1.1.1.86 Q2YUF3 TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELRE 6bul B 1.88 BS04 E9G B 1 P132 D190 E194 P131 D189 E193 1.1.1.86 Q2YUF3 TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIK 6bul B 1.88 BS07 NAP B 1 Y25 G26 S27 Q28 I47 R48 S52 L79 L80 P81 D82 Q85 V88 A106 H107 P129 P132 G133 Y24 G25 S26 Q27 I46 R47 S51 L78 L79 P80 D81 Q84 V87 A105 H106 P128 P131 G132 1.1.1.86 Q2YUF3 TTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIK 6buv B 1.86 BS01 E9A B 1 A108 D109 A112 S113 M115 S116 I144 L147 L148 L158 A105 D106 A109 S110 M112 S113 I135 L138 L139 L149 2.7.7.18 P9WJJ5 RRLGVMGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGHITSLLGQLAKDALTLVEIPALAISSTDCRQRAEQSRPLWYLMPDGVVQYVSKRRLYT 6c1i A 2.26 BS01 EEY A 1 F282 C285 R288 S289 H323 I326 L330 H449 L453 Y473 F69 C72 R75 S76 H110 I113 L117 H236 L240 Y260 P37231 30409975 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 6c1i A 2.26 BS02 KNA A 1 G284 C285 R288 I341 M348 L353 G71 C72 R75 I128 M135 L140 P37231 30409975 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 6c1i B 2.26 BS01 EEY B 1 F282 C285 Q286 R288 S289 H323 I326 L330 F363 H449 L453 F69 C72 Q73 R75 S76 H110 I113 L117 F150 H236 L240 P37231 30409975 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTEHPLLQEIYKDL 6c1i B 2.26 BS02 KNA B 1 I281 C285 M364 I68 C72 M151 P37231 30409975 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTEHPLLQEIYKDL 6c89 B 1.75 BS02 ZN B 2 H116 H118 H77 H79 E5KIY2 30375382 GDQRFGDLVFRQLAPNVWQHTSYLDMPGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIRDSKAKSLAQLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR 6cyt B 3.50 BS01 NUC N 1 R251 R254 R259 R245 R248 R253 O60563 NNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIWNWRAC 6cyt D 3.50 BS01 NUC N 1 N24 Y26 N24 Y26 A0A0C5HAL9 MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG 6dhb A 1.70 BS01 CA A 1 I92 P93 G94 N97 D98 I92 P93 G94 N97 D98 Q8TDQ0 MVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDEKFNLKLVIK 6di2 A 1.32 BS01 SF4 A 1 P334 C336 C417 I420 C434 F436 T471 C474 P500 P19 C21 C102 I105 C119 F121 T156 C159 P171 2.7.7.- C7GP29 DDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRLSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHIAHPNLYFERSRQLQK 6dsz A 3.09 BS01 III C 1 E27 L29 V44 T45 A46 E47 G48 V264 D265 R270 M282 L284 R301 E303 L305 Y316 D318 N319 G320 V321 L333 L336 N337 V338 D339 Y346 M350 E351 E27 L29 V44 T45 A46 E47 G48 V264 D265 R270 M282 L284 R301 E303 L305 Y316 D318 N319 G320 V321 L333 L336 N337 V338 D339 Y346 M350 E351 Q16531 MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSTSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLATADDLIKVVEELTRIH 6dsz B 3.09 BS01 III D 1 E27 L29 V44 T45 A46 E47 V264 D265 R270 M282 L284 R301 E303 L305 Y316 L317 D318 N319 G320 V321 L333 L336 N337 V338 D339 Y346 M350 E351 E27 L29 V44 T45 A46 E47 V260 D261 R266 M278 L280 R297 E299 L301 Y312 L313 D314 N315 G316 V317 L329 L332 N333 V334 D335 Y342 M346 E347 Q16531 MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLRQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIIKGLWPLRSRETDDTLVLSFVGQTRVLMLNGEELMGFVDDQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFEHYLLCALGDGALFYFGLNIETGLLDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVILVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDGTTALRPSASTQALSSSVSSSKLFSSSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVADDLIKVVEELTRIH 6du0 A 1.82 BS01 SF4 A 1 P334 C336 C417 C434 F436 C474 P500 P18 C20 C99 C116 F118 C156 P168 2.7.7.- P20457 DEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKELRYSFRHNYGLERINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHIAHPNLYFERSRQLQK 6e4p B 1.95 BS01 NUC K 1 W215 K219 T229 F230 C231 W15 K19 T29 F30 C31 Q389P7 HMRVQVSGLSDETTWHTLKDHLRQAGEVTFCKVFSGGRAVVEFVTPEDAARAITELQASELEGATLFLR 6e4p C 1.95 BS01 NUC J 1 Q224 T254 E255 L256 S259 E260 Q23 T53 E54 L55 S58 E59 Q389P7 MRVQVSGLSDETTWHTLKDHLRQAGEVTFCKVFSGGRAVVEFVTPEDAARAITELQASELEGATLFLR 6e59 A 3.40 BS01 L76 A 1 F90 N109 P112 I113 V116 Q165 E193 H197 I204 F264 F268 Y272 F63 N82 P85 I86 V89 Q138 E166 H170 I177 F423 F427 Y431 P25103 PAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEGIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEGWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAGDPGELANAILKALELSRSDLSKFRENCKKRAMSFSEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAF 6e5x A 1.50 BS01 III B 1 E197 L199 Q203 P206 E209 V210 R213 A225 L226 Q229 W230 S234 M237 E58 L60 Q64 P67 E70 V71 R74 A86 L87 Q90 W91 S95 M98 Q77DJ5 PKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLCETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVP 6e5x A 1.50 BS02 CA A 1 A155 N244 A16 N105 Q77DJ5 PKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLCETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVP 6ecd A 1.90 BS01 III B 1 P2398 A2399 S2463 L2464 L2495 Q2568 P22 A23 S85 L86 L117 Q165 3.1.2.- Q1PSF3 DPTAKLVRLNPGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLKVFILAMGIGGMLDQEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGLP 6ece A 2.00 BS01 III C 1 A2399 S2463 L2464 I2498 P2499 A2501 F2513 M2517 L2572 H2625 A24 S88 L89 I121 P122 A124 F136 M140 L179 H232 3.1.2.- Q1PSF3 PTAKLVRLNPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLIPVADADLTEEETKVFILAMPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGLP 6ece B 2.00 BS01 VAL D 1 A2399 S2463 L2464 F2513 M2517 L2572 A16 S80 L81 F120 M124 L163 3.1.2.- Q1PSF3 KLVRLNGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLTEEETKVFILAMPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCG 6ecf A 2.50 BS01 III G 1 A2399 S2463 L2464 F2513 M2517 R2545 Q2568 L2572 H2625 A25 S89 L90 F129 M133 R148 Q171 L175 H228 3.1.2.- Q1PSF3 DPTAKLVRLNPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLTEEETKVFILAMKDLPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGLP 6ecf B 2.50 BS01 III I 1 P2398 A2399 S2463 L2464 F2513 M2517 R2545 L2572 H2625 P23 A24 S88 L89 F129 M133 R148 L175 H228 3.1.2.- Q1PSF3 PTAKLVRLNPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLGTEEETKVFILAMGDLPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGLPS 6ecf C 2.50 BS01 III H 1 P2398 A2399 S2463 L2464 F2513 M2517 Q2568 L2572 P23 A24 S88 L89 F129 M133 Q172 L176 3.1.2.- Q1PSF3 PTAKLVRLNPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLGDEEETKVFILAMGKDLPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGLP 6ecf D 2.50 BS01 III K 1 A2399 S2463 L2464 L2495 I2498 M2517 L2572 S2575 H2625 A23 S87 L88 L119 I122 M135 L190 S193 H243 3.1.2.- Q1PSF3 TAKLVRLNPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLGDIPTEEETKVFILAMGIGGMLDQDRDALKDLPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGL 6ecf E 2.50 BS01 III J 1 A2399 S2463 L2464 F2513 M2517 L2572 H2625 A21 S85 L86 F127 M131 L186 H238 3.1.2.- Q1PSF3 KLVRLNPRGGDGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLGDIEEETKVFILAMGIGGMLDQDRDALKDLPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGLPS 6ecf F 2.50 BS01 III L 1 A2399 S2463 L2464 L2495 F2513 M2517 L2572 H2625 A22 S86 L87 L118 F124 M128 L183 H236 3.1.2.- Q1PSF3 PTAKLVRLNPRGGPGIVFAPPAGGTVLGYIELARHLKGFGEIHGVEAPGLGAGETPVYPSFEEMVQFCSDSAAGVAGDGVYIGGHSLGGHIAFYLATMLLDRGIRPKGLIILDTPPRLEETKVFILAMGIGGMLDQDRDALKDLPYEEAKQLLLDRAKNDPRVSAFLSEDYLDRFLRLQMHQLMYSRDVVLPQRKLDIPIHVFRTKNHAPEVARLFSAWENYAAGEVTFVDIPGDHATMLRAPHVSEVAQLLDRHCGL 6ect A 1.42 BS01 SAM A 1 Q-3 N-1 L976 T977 R1015 F1033 G1034 G1036 T1057 I1058 Q1062 R1084 D1085 S1086 F1101 E1102 L1106 I1107 Q7 N9 L13 T14 R52 F70 G71 G73 T94 I95 Q99 R121 D122 S123 F138 E139 L143 I144 Q8RJY2 30489068 TENLYFQSNEHFLTWGVFQEIVPGFSWIRTVFRPSERPEGRERLAVAQRELRRVLFRAVDLSAIKNVMDFGCGHGSDLIILGEQNEHLKLDGYTISGKQAEVCKQRVRTRGLQNRIRIFQRDSAKDDFPGMYDLVLGFEVAGLIPDKDALFSNIDRHLTNGGLLIMADFVANTTFSSTREQWNKLFSSNHLRLVDAVDVSNEVANCLHNPDYAAQFEALCKELKQRSFGSYENVYKALRGGLISYVLFHVQKDRFSRSDELFHLNAKQFEQLTPYAEFA 6ecu A 1.96 BS01 SAH A 1 Y982 L983 T984 R1022 F1040 G1041 C1042 G1043 D1047 T1064 L1065 Q1069 R1091 D1092 S1093 F1109 E1110 V1111 I1115 Y3 L4 T5 R43 F61 G62 C63 G64 D68 T85 L86 Q90 R112 D113 S114 F130 E131 V132 I136 Q8RJY3 30489068 ESYLTFGVLNEKQPGFSWLRVAYGLDPSEERMRLLLHSQRALRNVLLDSVDFSRAKSVWDFGCGYASDIIALGERHSHLKLHGHTLSSEQAELGLRKIEARGLGGRVQVLRRDSSKDAPLESAYDVILGFEVATHIKEKRSLFQNLSSHLREGGFMLLADFIANSYNVTPSQWVELLSEHGLRLVECVDVSQEVANFLFDADFDANLTQLETSVGISAIEKRNYQAMRNFGAALERKILSYVLFIAQKDSHVRSTYLRHINQKWVEAPAPYAARE 6ecu B 1.96 BS01 SAH B 1 F1040 G1041 G1043 T1064 L1065 Q1069 R1091 D1092 S1093 F1109 E1110 V1111 H1114 I1115 F62 G63 G65 T86 L87 Q91 R113 D114 S115 F131 E132 V133 H136 I137 Q8RJY3 30489068 DESYLTFGVLNEKQPGFSWLRVAYGLDPSEERMRLLLHSQRALRNVLLDSVDFSRAKSVWDFGCGYASDIIALGERHSHLKLHGHTLSSEQAELGLRKIEARGLGGRVQVLRRDSSKDAPLESAYDVILGFEVATHIKEKRSLFQNLSSHLREGGFMLLADFIANASYNVTPSQWVELLSEHGLRLVECVDVSQEVANFLFDADFDANLTQLETSVGISAIEKRNYQAMRNFGAALERKILSYVLFIAQKDSHVRSTYLRHINQKWVEAPAPYAARELM 6ecv A 1.80 BS01 SAH A 1 R1022 F1040 G1041 G1043 T1064 L1065 Q1069 R1091 D1092 S1093 F1109 E1110 I1115 R43 F61 G62 G64 T85 L86 Q90 R112 D113 S114 F130 E131 I136 Q8RJY3 30489068 ESYLTFGVLNEKQPGFSWLRVAYGLDPSEERMRLLLHSQRALRNVLLDSVDFSRAKSVWDFGCGYASDIIALGERHSHLKLHGHTLSSEQAELGLRKIEARGLGGRVQVLRRDSSKDAPLESAYDVILGFEVATHIKEKRSLFQNLSSHLREGGFMLLADFIANSGSGVDVQDIASYNVTPSQWVELLSEHGLRLVECVDVSQEVANFLFDADFDANLTQLETSVGISAIEKRNYQAMRNFGAALERKILSYVLFIAQKDSHVRSTYLRHINQKWVEAPAPYAARE 6ecw A 1.70 BS01 SAH A 1 E980 T984 R1022 F1040 G1041 G1043 T1064 L1065 Q1069 R1091 D1092 S1093 F1109 E1110 H1114 I1115 E3 T7 R45 F63 G64 G66 T87 L88 Q92 R114 D115 S116 F132 E133 H137 I138 Q8RJY3 30489068 VDESYLTFGVLNEKQPGFSWLRVAYGLDPSEERMRLLLHSQRALRNVLLDSVDFSRAKSVWDFGCGYASDIIALGERHSHLKLHGHTLSSEQAELGLRKIEARGLGGRVQVLRRDSSKDAPLESAYDVILGFEVATHIKEKRSLFQNLSSHLREGGFMLLADFIANSGSSYNVTPSQWVELLSEHGLRLVECVDVSQEVANFLFDADFDANLTQLETSVGISAIEKRNYQAMRNFGAALERKILSYVLFIAQKDSHVRSTYLRHINQKWVEAPAPYAAREL 6ecx A 1.90 BS01 SAM A 1 L957 L976 T977 R1015 F1033 G1034 G1036 T1057 I1058 Q1062 R1084 D1085 S1086 F1101 E1102 V1103 L1106 I1107 L10 L14 T15 R53 F71 G72 G74 T95 I96 Q100 R122 D123 S124 F139 E140 V141 L144 I145 Q8RJY2 30489068 GIIASFYDSLVHFLTWGVFQEIVPGFSWIRTVFRPSERPEGRERLAVAQRELRRVLFRAVDLSAIKNVMDFGCGHGSDLIILGEQNEHLKLDGYTISGKQAEVCKQRVRTRGLQNRIRIFQRDSAKDDFPGMYDLVLGFEVAGLIPDKDALFSNIDRHLTNGGLLIMADFVANTTFSSTREQWNKLFSSNHLRLVDAVDVSNEVANCLHNPDYAAQFEALCKELDEVTQRSFGSYENVYKALRGGLISYVLFHVQKDRFSRSDELFHLNAKQFEQLTPYAEFA 6ekw A 1.43 BS01 HEM A 1 P35 C36 P37 G38 L39 V63 F67 F69 A77 T78 A81 F121 E122 G123 S126 M127 T128 R189 E196 F199 L203 F204 P33 C34 P35 G36 L37 V61 F65 F67 A75 T76 A79 F119 E120 G121 S124 M125 T126 R187 E194 F197 L201 F202 1.11.2.1 B9W4V6 GLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6ekx A 1.13 BS03 1NP A 1 F69 A77 F121 T192 G195 F199 F66 A74 F118 T189 G192 F196 1.11.2.1 B9W4V6 LPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6ekx A 1.13 BS04 1NP A 2 F191 G195 S240 G241 V244 F188 G192 S237 G238 V241 1.11.2.1 B9W4V6 LPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6eky A 1.23 BS05 1NP A 3 F274 P277 A317 F271 P274 A314 1.11.2.1 B9W4V6 LPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6eky A 1.23 BS06 1NP A 4 P277 M280 G314 A316 P274 M277 G311 A313 1.11.2.1 B9W4V6 LPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6ekz A 1.08 BS03 SNP A 1 D70 F191 G195 F199 S240 G241 V244 D68 F189 G193 F197 S238 G239 V242 1.11.2.1 B9W4V6 GLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6ekz A 1.08 BS04 SNP A 2 F76 F191 F274 P277 M280 F74 F189 F272 P275 M278 1.11.2.1 B9W4V6 GLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6ekz A 1.08 BS05 SNP A 3 R220 F225 R227 R218 F223 R225 1.11.2.1 B9W4V6 GLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6ekz A 1.08 BS06 SNP A 4 K290 P294 V298 R301 Y325 K288 P292 V296 R299 Y323 1.11.2.1 B9W4V6 GLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6el4 A 1.53 BS03 VOH A 1 F69 A73 A77 F121 T192 G195 E196 F199 F68 A72 A76 F120 T191 G194 E195 F198 1.11.2.1 B9W4V6 PGLPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPAQIINAVQEGFNFDNQAAIFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVVQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFLFQGVAAGCTQVFPYGR 6eyd D 4.20 BS03 MG D 1 D537 D539 D528 D530 2.7.7.6 A0QS66 VNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEAEMAVEKKAVEDQRDADLEARAQKLEADLAELEDVRRKVRDSGEREMRQLRDRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAESIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQGVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGDAWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKYQRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGNLTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDIRDAHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVRSVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTGGLPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVYDKLSKRQRLRVGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHLVKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERAEFEAENRRVVAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAA 6ez9 A 1.61 BS04 C68 A 1 R210 N257 M424 E425 G427 L428 G518 N519 R534 R536 F546 Y552 H553 K699 Y700 R156 N203 M370 E371 G373 L374 G464 N465 R480 R482 F489 Y495 H496 K642 Y643 3.4.17.21 Q04609 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAMEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 6ezl A 2.07 BS01 PLP A 1 H44 S101 G102 T103 L106 W130 N184 D212 A214 Y215 S245 S247 K248 H43 S93 G94 T95 L98 W122 N176 D204 A206 Y207 S237 S239 K240 2.6.1.1 Q4D080 RCLWNNIAALPADPIFSASLVAKKAPEPKADLIIGAYRDAEGHPYPLNVVRKAEQRLLYLPMSGYAPFIEESLKIAYGDSVARENVVGIQGLSGTGSLSIGACFLARVLSRDTPVYISDPTWPNHYAVMAAANLTDLRKYRYYDNAKRCIDFDGLLEDLNGAPEGSIVILHACAHNPTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQSYSKNMGLYAERVGVCSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVLSDPELRAGWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKAQCEKLIERRVFVLPSGRANMAGLTKRSVELLVKGIDEVVRTV 6ezl B 2.07 BS01 PLP B 1 H44 S101 G102 T103 L106 W130 H179 N184 D212 A214 Y215 S245 S247 K248 Y253 H42 S92 G93 T94 L97 W121 H170 N175 D203 A205 Y206 S236 S238 K239 Y244 2.6.1.1 Q4D080 CLWNNIAALPADPIFSASLVAKKAPEPKADLIIGAYRDAEGHPYPLNVVRKAEQRLLELPMSGYAPFIEESLKIAYGDSVARENVVGIQGLSGTGSLSIGACFLARVLSRDTPVYISDPTWPNHYAVMAAANLTDLRKYRYYDNAKRCIDFDGLLEDLNGAPEGSIVILHACAHNPTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQSYSKNMGLYAERVGVCSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVLSDPELRAGWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKAQCEKLIERRVFVLPSGRANMAGLTKRSVELLVKGIDEVVRTVT 6ezs A 2.50 BS01 NAG A 1 R274 D437 W487 W505 Y530 D532 W546 W582 E584 R271 D434 W484 W502 Y527 D529 W543 W579 E581 3.2.1.52 D9ISE0 SEYRVDLVVLSEQKQNCRFGLTFHNLSDQDLNSWGLTFAFDRYILPDSVSNGQLTQIGSFCTLKPEGIVLAANHHYYCEFSIGSNPFRYYSDGFNEAMIDFVVDGQPQRAQVDVTPIVLASPYRERSDIPASLTHAQPLLPKPNHIEVSDHSFTFDEQAGVAIYTDLANSAKAWLLEELQRIHQFTLSSSNSGKIIFKSNPTLDEGAYKLKVSEESIKIEAGSSSGFTHACATLLQLLKRDEATKTMEAVCCSIIDSPRFRYRGMMLDCARHFHSVEQVKRLINLLAHYKLNTFHWHLTDDEGWRVEIKSLPQLTEIGAWRGIDETIEPQYTHLSQRYGGFYTQEEIRDVIAFAEQRGITIIPEIDVPGHCRAAIKSLPHLLIEAEDTTEYRSIQHYNDNVINPALPGSYEFIDKVLEEIAALFPAPYVHIGADEVPNGVWSKSPACQALMEQLGYTDYKELQGHFLRHAEDKLRKLGKRMLGWEEAQHGNKVSKDTVIYSWLSEEAALNCARQGFDVVLQPAQTTYLDMTQDYAPEEPGVDWANPLPLEKAYNYEPLAEVPADDPIRKRIWGIQTALWCEIINNPSRMDYMIFPRLTAMAEACWTEKQHRDWTDYLSRLKGHLPLLDLQGVNYRKPWK 6ezu A 2.04 BS01 ZN A 1 H421 H457 D458 D575 H87 H123 D124 D241 3.1.4.- G4VPI6 LPIHGVETPNDNELEERFSLCLDEWGVDIFEIDRLSNGHALTTVAYRIFQKRDLLKTFCIDPHVFVRYLLRVESTYHADVPYHNSMHAADVLQTAHFLLQAEALDDVFSDLEILAVLFAAAIHDVDHPGVTNQFLINTGHELALQYNDASVLENHHLYMAFKILTEKDCDIFANLGGKKRQTLRRMVIELVLATDMSKHMSLLADLRTMVETKKVSGSGMLNLDNYADRIQILQNMIHCADLSNPAKPLRLYRKWTGRLIEEFFRQGDKERELSLEISPMCDRESVEVEKSQVSFIDFVCHPLWETWCDLVHPCAQLILDTLEDNRDWYECHI 6ezu A 2.04 BS02 CMP A 1 H417 H421 D458 M530 D575 L576 N578 L593 M614 Q626 F629 H83 H87 D124 M196 D241 L242 N244 L259 M280 Q292 F295 3.1.4.- G4VPI6 LPIHGVETPNDNELEERFSLCLDEWGVDIFEIDRLSNGHALTTVAYRIFQKRDLLKTFCIDPHVFVRYLLRVESTYHADVPYHNSMHAADVLQTAHFLLQAEALDDVFSDLEILAVLFAAAIHDVDHPGVTNQFLINTGHELALQYNDASVLENHHLYMAFKILTEKDCDIFANLGGKKRQTLRRMVIELVLATDMSKHMSLLADLRTMVETKKVSGSGMLNLDNYADRIQILQNMIHCADLSNPAKPLRLYRKWTGRLIEEFFRQGDKERELSLEISPMCDRESVEVEKSQVSFIDFVCHPLWETWCDLVHPCAQLILDTLEDNRDWYECHI 6f02 A 3.00 BS01 FUL A 1 H118 V162 H73 V117 P29622 SPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP 6f02 C 3.00 BS01 FUL C 1 L91 K154 D158 V162 L47 K110 D114 V118 P29622 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP 6f0b A 2.80 BS01 HEM A 1 F83 V84 H91 R95 F102 L230 G233 G234 T237 T238 T241 V279 S280 L284 R286 L309 G336 F337 H342 C344 V345 G346 L349 A350 F71 V72 H79 R83 F90 L218 G221 G222 T225 T226 T229 V267 S268 L272 R274 L297 G324 F325 H330 C332 V333 G334 L337 A338 Q8VS75 SPLEPYHIYPEAKSCPVAKVGLWNGTPAHVFSGYEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLRGTIAREFLPKHIELLRPAIREIVQGVLDGLAETAPPQDMLEAFAVPVASATVFRLLGIPAEDRALLTRCVKGVVSAVGSEDEGAEVFRTLGEYIGGLVQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHEHPERIPLLVEELLRYHTVSQLGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDRPSVPHVGFGYGPHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW 6f0b A 2.80 BS02 C8H A 1 E69 L74 P82 V84 F182 L228 M229 V232 G233 S280 T385 E57 L62 P70 V72 F170 L216 M217 V220 G221 S268 T373 Q8VS75 SPLEPYHIYPEAKSCPVAKVGLWNGTPAHVFSGYEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLRGTIAREFLPKHIELLRPAIREIVQGVLDGLAETAPPQDMLEAFAVPVASATVFRLLGIPAEDRALLTRCVKGVVSAVGSEDEGAEVFRTLGEYIGGLVQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHEHPERIPLLVEELLRYHTVSQLGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDRPSVPHVGFGYGPHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW 6f0c A 1.70 BS01 HEM A 1 F83 V84 H91 R95 F102 V147 G233 G234 T237 T238 T241 L274 V279 L284 R286 L309 G336 F337 G338 H342 C344 V345 G346 A350 F71 V72 H79 R83 F90 V135 G221 G222 T225 T226 T229 L262 V267 L272 R274 L297 G324 F325 G326 H330 C332 V333 G334 A338 Q8VS75 SPLEPYHIYPEAKSCPVAKVGLWNGTPAHVFSGYEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLRGTIAREFLPKHIELLRPAIREIVQGVLDGLAETAPPQDMLEAFAVPVASATVFRLLGIPAEDRALLTRCVKGVVSAVGSEDEGAEVFRTLGEYIGGLVQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHEHPERIPLLVEELLRYHTVSQLGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDRPSVPHVGFGYGPHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW 6f0c A 1.70 BS02 C8B A 1 E69 L74 Q77 P82 V84 F182 L228 M229 V232 G233 L284 T385 E57 L62 Q65 P70 V72 F170 L216 M217 V220 G221 L272 T373 Q8VS75 SPLEPYHIYPEAKSCPVAKVGLWNGTPAHVFSGYEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLRGTIAREFLPKHIELLRPAIREIVQGVLDGLAETAPPQDMLEAFAVPVASATVFRLLGIPAEDRALLTRCVKGVVSAVGSEDEGAEVFRTLGEYIGGLVQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHEHPERIPLLVEELLRYHTVSQLGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDRPSVPHVGFGYGPHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW 6f0c A 1.70 BS03 OXY A 1 G233 T237 G221 T225 Q8VS75 SPLEPYHIYPEAKSCPVAKVGLWNGTPAHVFSGYEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLRGTIAREFLPKHIELLRPAIREIVQGVLDGLAETAPPQDMLEAFAVPVASATVFRLLGIPAEDRALLTRCVKGVVSAVGSEDEGAEVFRTLGEYIGGLVQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHEHPERIPLLVEELLRYHTVSQLGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDRPSVPHVGFGYGPHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW 6f14 A 1.87 BS01 III B 1 E127 F129 S130 R133 K168 P169 E170 F187 G200 T201 E203 E230 G234 Y235 P236 F239 A240 D241 I246 D328 Y330 E116 F118 S119 R122 K157 P158 E159 F176 G189 T190 E192 E219 G223 Y224 P225 F228 A229 D230 I235 D317 Y319 2.7.11.11 P25321 KGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6f14 A 1.87 BS02 ISQ A 1 L49 V57 A70 E121 Y122 V123 L173 F327 L42 V46 A59 E110 Y111 V112 L162 F316 2.7.11.11 P25321 KGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 6f1g A 1.67 BS02 AHR A 1 F165 W166 E196 P197 F165 W166 E196 P197 3.2.1.99 B3EYM8 MVHFHPFGGVNFYEMDWSLKGDLWAHDPVIAKEGSRWYVFHTGSGIQIKTSEDGVHWENMGWVFPSLPDWYKQYVPEKDEDHLWAPDICFYNGIYYLYYSVSTFGKNTSVIGLATNQTLDPRDPDYEWKDMGPVIHSTASDNYNAIDPNVVFDQEGQPWLSFGSFWSGIQLIQLDTETMKPAAQAELLTIASRGEEPNAIAAPFIVCRNGYYYLFVSFDFCCRGIESTYKIAVGRSKDITGPYVDKNGVSMMQGGGTILDEGNDRWIGPGHCAVYFSGVSAILVNHAYDALKNGEPTLQIRPLYWDDEGWPYLSV 6f1g A 1.67 BS03 AHR A 2 G105 F165 G105 F165 3.2.1.99 B3EYM8 MVHFHPFGGVNFYEMDWSLKGDLWAHDPVIAKEGSRWYVFHTGSGIQIKTSEDGVHWENMGWVFPSLPDWYKQYVPEKDEDHLWAPDICFYNGIYYLYYSVSTFGKNTSVIGLATNQTLDPRDPDYEWKDMGPVIHSTASDNYNAIDPNVVFDQEGQPWLSFGSFWSGIQLIQLDTETMKPAAQAELLTIASRGEEPNAIAAPFIVCRNGYYYLFVSFDFCCRGIESTYKIAVGRSKDITGPYVDKNGVSMMQGGGTILDEGNDRWIGPGHCAVYFSGVSAILVNHAYDALKNGEPTLQIRPLYWDDEGWPYLSV 6f1g A 1.67 BS05 AHR A 4 D27 W84 A85 D147 C221 C222 Y229 H271 D27 W84 A85 D147 C221 C222 Y229 H271 3.2.1.99 B3EYM8 MVHFHPFGGVNFYEMDWSLKGDLWAHDPVIAKEGSRWYVFHTGSGIQIKTSEDGVHWENMGWVFPSLPDWYKQYVPEKDEDHLWAPDICFYNGIYYLYYSVSTFGKNTSVIGLATNQTLDPRDPDYEWKDMGPVIHSTASDNYNAIDPNVVFDQEGQPWLSFGSFWSGIQLIQLDTETMKPAAQAELLTIASRGEEPNAIAAPFIVCRNGYYYLFVSFDFCCRGIESTYKIAVGRSKDITGPYVDKNGVSMMQGGGTILDEGNDRWIGPGHCAVYFSGVSAILVNHAYDALKNGEPTLQIRPLYWDDEGWPYLSV 6f1g A 1.67 BS06 AHR A 5 H26 T42 W84 C222 H26 T42 W84 C222 3.2.1.99 B3EYM8 MVHFHPFGGVNFYEMDWSLKGDLWAHDPVIAKEGSRWYVFHTGSGIQIKTSEDGVHWENMGWVFPSLPDWYKQYVPEKDEDHLWAPDICFYNGIYYLYYSVSTFGKNTSVIGLATNQTLDPRDPDYEWKDMGPVIHSTASDNYNAIDPNVVFDQEGQPWLSFGSFWSGIQLIQLDTETMKPAAQAELLTIASRGEEPNAIAAPFIVCRNGYYYLFVSFDFCCRGIESTYKIAVGRSKDITGPYVDKNGVSMMQGGGTILDEGNDRWIGPGHCAVYFSGVSAILVNHAYDALKNGEPTLQIRPLYWDDEGWPYLSV 6f25 A 3.05 BS01 CVZ A 1 W86 Y124 E202 S203 W286 H287 V294 F295 Y337 F338 Y341 W439 H447 W82 Y120 E198 S199 W276 H277 V284 F285 Y327 F328 Y331 W429 H437 3.1.1.7 P22303 DAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSAT 6f25 B 3.05 BS01 CVZ B 1 W86 G121 Y124 E202 S203 W286 H287 P290 Q291 E292 Y337 F338 Y341 H447 W82 G117 Y120 E198 S199 W278 H279 P282 Q283 E284 Y329 F330 Y333 H439 3.1.1.7 P22303 DAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSAT 6f4v A 1.80 BS01 NTP A 1 D258 R259 Y260 R300 L304 D212 R213 Y214 R254 L258 P29622 GSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 6f5k A 1.62 BS01 CU A 1 H431 C503 H508 H430 C502 H507 G2QG31 QSCNTPSNRACWTDGYDINTDYEVDSPDTGVVRPYTLTLTEVDNWTGPDGVVKEKVMLVNNSIIGPTIFADWGDTIQVTVINNLETNGTSIHWHGLHQKGTNLHDGANGITECPIPPKGGRKVYRFKAQQYGTSWYHSHFSAQYGNGVVGAIQINGPASLPYDTDLGVFPISDYYYSSADELVELTKNSGAPFSDNVLFNGTAKHPETGEGEYANVTLTPGRRHRLRLINTSVENHFQVSLVNHTMTIIAADMVPVNAMTVDSLFLGVGQRYDVVIEASRTPGNYWFNVTFGGGLLCGGSRNPYPAAIFHYAGAPGGPPTDEGKAPVDHNCLDLPNLKPVVARDVPLSGFAKRPDNTLDVTLDTTGTPLFVWKVNGSAINIDWGRPVVDYVLTQNTSFPPGYNIVEVNGADQWSYWLIENDPGAPFTLPHPMHLHGHDFYVLGRSPDESPASNERHVFDPARDAGLLSGANPVRRDVTMLPAFGWVVLAFRADNPGAWLFHCHIAWHVSGGLGVVYLERADDLRGAVSDADADDLDRLCADWRRYWPTNPYPKSDSGL 6f5k A 1.62 BS02 CU A 2 H93 H434 H436 H92 H433 H435 G2QG31 QSCNTPSNRACWTDGYDINTDYEVDSPDTGVVRPYTLTLTEVDNWTGPDGVVKEKVMLVNNSIIGPTIFADWGDTIQVTVINNLETNGTSIHWHGLHQKGTNLHDGANGITECPIPPKGGRKVYRFKAQQYGTSWYHSHFSAQYGNGVVGAIQINGPASLPYDTDLGVFPISDYYYSSADELVELTKNSGAPFSDNVLFNGTAKHPETGEGEYANVTLTPGRRHRLRLINTSVENHFQVSLVNHTMTIIAADMVPVNAMTVDSLFLGVGQRYDVVIEASRTPGNYWFNVTFGGGLLCGGSRNPYPAAIFHYAGAPGGPPTDEGKAPVDHNCLDLPNLKPVVARDVPLSGFAKRPDNTLDVTLDTTGTPLFVWKVNGSAINIDWGRPVVDYVLTQNTSFPPGYNIVEVNGADQWSYWLIENDPGAPFTLPHPMHLHGHDFYVLGRSPDESPASNERHVFDPARDAGLLSGANPVRRDVTMLPAFGWVVLAFRADNPGAWLFHCHIAWHVSGGLGVVYLERADDLRGAVSDADADDLDRLCADWRRYWPTNPYPKSDSGL 6f5k A 1.62 BS04 CU A 4 H95 W136 H138 H504 H94 W135 H137 H503 G2QG31 QSCNTPSNRACWTDGYDINTDYEVDSPDTGVVRPYTLTLTEVDNWTGPDGVVKEKVMLVNNSIIGPTIFADWGDTIQVTVINNLETNGTSIHWHGLHQKGTNLHDGANGITECPIPPKGGRKVYRFKAQQYGTSWYHSHFSAQYGNGVVGAIQINGPASLPYDTDLGVFPISDYYYSSADELVELTKNSGAPFSDNVLFNGTAKHPETGEGEYANVTLTPGRRHRLRLINTSVENHFQVSLVNHTMTIIAADMVPVNAMTVDSLFLGVGQRYDVVIEASRTPGNYWFNVTFGGGLLCGGSRNPYPAAIFHYAGAPGGPPTDEGKAPVDHNCLDLPNLKPVVARDVPLSGFAKRPDNTLDVTLDTTGTPLFVWKVNGSAINIDWGRPVVDYVLTQNTSFPPGYNIVEVNGADQWSYWLIENDPGAPFTLPHPMHLHGHDFYVLGRSPDESPASNERHVFDPARDAGLLSGANPVRRDVTMLPAFGWVVLAFRADNPGAWLFHCHIAWHVSGGLGVVYLERADDLRGAVSDADADDLDRLCADWRRYWPTNPYPKSDSGL 6f5n B 2.20 BS01 NI A 1 H28 E32 H23 E27 MQFKLILNGKTLKGVITIEAVDHAEAEKFFKQYANDNGVDGEWTYDEATHTFTVTE 6f5q A 1.43 BS02 CTK A 1 H90 Y136 T188 F189 A190 H192 K210 W212 H280 H80 Y126 T178 F179 A180 H182 K200 W202 H270 1.14.11.- Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 6f5r A 1.61 BS02 CQZ A 1 Y136 F189 A190 H192 K210 W212 K245 H280 Y126 F179 A180 H182 K200 W202 K235 H270 1.14.11.- Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWK 6f5s A 1.48 BS02 CQT A 1 D139 Y179 Y181 F189 H192 E194 D195 K210 W212 K245 H280 T318 D129 Y169 Y171 F179 H182 E184 D185 K200 W202 K235 H270 T308 1.14.11.- Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 6f5t A 1.58 BS02 CQK A 1 Y136 Y181 F189 H192 E194 K210 W212 K245 H280 Y126 Y171 F179 H182 E184 K200 W202 K235 H270 1.14.11.- Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 6f9q A 1.40 BS01 NAD A 1 G21 S24 G25 I26 D46 I47 Q48 C69 D70 V71 N97 A98 G99 V100 V122 N150 A151 G152 Y165 K169 P195 M196 A197 V198 T200 P201 L202 T203 G13 S16 G17 I18 D38 I39 Q40 C61 D62 V63 N89 A90 G91 V92 V114 N142 A143 G144 Y157 K161 P187 M188 A189 V190 T192 P193 L194 T195 5.4.99.- KKKLEGKVAIVTGGASGIGEATARLFVKYGARAVVIADIQSELGRSVAESIGKERCSFVQCDVADEEQVKSMIEWTATTYGGLDVMFSNAGVLNSAAQTVKDLDLPLFDKVMRVNTRGAAVCVKQAARKMVELGRGGSIICNAGSSAVRGAHGVTDYVMSKHAVIGLVRSASMQLGAHSIRVNSVSPMAVATPLTRNQGISTPDDVQKFLMPFISLKGVPPTAEQVAEAAAFLGSDEAAFVTGHDLPVDGGVLCMPF 6fyq A 2.00 BS01 PLP A 1 G115 S116 N119 Y148 H149 G150 E211 D244 V246 I247 K273 G114 S115 N118 Y147 H148 G149 E210 D243 V245 I246 K272 2.6.1.18 30401905 RSLTELDKKHFIHPFSSIQEQQHKGAKVIMKEGDGIYLTDVTGKTYIDGVSSLWNVNVGHGRVELAEAAAQQMKKMAFSSAFSTFSHEPAIRLAEKIASITPEGLNAVFFTSGGSESNDSAVKLVRHYWKIQGKPNKRKIISLKRSYHGVAAASTSVTGIPEFWGMAGHMMTDFLHVDTHYNNTTEQAVQSLCQAIEEAGPETIAAFFAEPVQGAGGVIIPPEDYFLRIREVCNAYGILFVADEVITGFGRTGKMFGIENWDVIPDVMTFAKGVTSGYFPLGGVVVSDPIHEVLKEKSVGTLFHGFTYSGHPTAAAVALKNIAIIKEERLVENSKRMGDALLHGLKKVKNRLEIVGDVRFVGLLGAVELMQNPATNKPFSSNLQVAPKVIEALHELGVICRSVTYDHTNIICLAPPLIINQKQVDKLVEVIYEAILKVQQQLG 6gna A 1.30 BS01 FAD A 1 G10 S11 G12 P13 A14 G33 S34 L37 S38 K39 K40 L43 A44 P45 N49 V79 K80 V81 A108 M109 G110 D219 S220 G254 D255 Y261 Q262 Y263 A266 G11 S12 G13 P14 A15 G33 S34 L37 S38 K39 K40 L43 A44 P45 N49 V79 K80 V81 A108 M109 G110 D219 S220 G254 D255 Y261 Q262 Y263 A266 Q97EM8 30510005 HMERYDIAIIGSGPAGLASAINAKTRKSVIVFGSSDLSKKLTLAPVINNYLGFYGIRGAELQEKFKEHIDNMGIQIENVKVNNIYAMGEYFSIMTSKDTYEASKVILAMGMEHTKPLKGEDKFLGRGVGYCATCDAPLYKGKIVTIVGYNKEAESEANYLAELASKVYYVPRYKDEYQLVSAVEIVKDVPVEIVGDKKVEKLKLKSRELETDGVFVLKDSAPPEQLVPGLYVEDGHIKVNRKMETNIDGCYAAGDCTGKPYQYMKAVGEGQVAALNAVEKLYTK 6gnc A 1.64 BS01 FAD A 1 I9 G10 S11 G12 P13 A14 G33 S34 L37 S38 K40 K43 A44 I47 N49 E79 K80 V81 A108 S109 G110 D219 S220 G254 D255 Y261 Q262 Y263 S266 I9 G10 S11 G12 P13 A14 G33 S34 L37 S38 K40 K43 A44 I47 N49 E79 K80 V81 A108 S109 G110 D219 S220 G254 D255 Y261 Q262 Y263 S266 Q97IU2 30510005 MDRYDIAIIGSGPAGLSAAINAVIRNKKVILFGSDNLSNKLLKAPKINNYLGIYDVSGKELKEKFLEHLKYMNIEIKNEKVNSVYSMGDYFALSLNQKMYEATSIIIASGVEFSKPLNGEDELLGKGVGYCATCDAPLYKGKTVAIVGYTKEAEEEANYVSELAGKLYYIPMYKDKVSLKEVIEVVEDKPISILGKDKVSGLQMSKGEINTDAVFIIKDSVSPGKLVPGLLMNGEHIAVDIDMKTNIEGCFAAGDCAGRPYQYIKSAGQGQIAALSAVSYIDKIKLN 6gnd A 2.89 BS01 FAD A 1 G10 S11 G12 P13 S34 D36 L37 S38 K40 L43 A44 P45 I47 N49 V81 A108 M109 G254 D255 Y261 Q262 Y263 G9 S10 G11 P12 S33 D35 L36 S37 K39 L42 A43 P44 I46 N48 V80 A107 M108 G250 D251 Y257 Q258 Y259 Q97EM8 30510005 ERYDIAIIGSGPAGLASAINAKTRNKSVIVFGSSDLSKKLTLAPVINNYLGFYGIRGAELQEKFKEHIDNMGIQIENVKVNNIYAMGEYFSIMTSKDTYEASKVILAMGMEHTKPLKGEDKFLVGYSATCDAPLYKGKIVTIVGYNKEAESEANYLAELASKVYYVPRYKDEYQLVSAVEIVKDVPVEIVGDKKVEKLKLKSRELETDGVFVLKDSAPPEQLVPGLYVEDGHIKVNRKMETNIDGCYAAGDCTGKPYQYMKAVGEGQVAALNAVEKLYT 6gnd C 2.89 BS01 FAD C 1 G10 S11 G12 P13 A14 S34 L37 S38 K40 L43 A44 P45 N49 V79 V81 A108 M109 L226 G254 D255 Y261 Q262 Y263 G10 S11 G12 P13 A14 S34 L37 S38 K40 L43 A44 P45 N49 V79 V81 A108 M109 L223 G251 D252 Y258 Q259 Y260 Q97EM8 30510005 MERYDIAIIGSGPAGLASAINAKTRNKSVIVFGSSDLSKKLTLAPVINNYLGFYGIRGAELQEKFKEHIDNMGIQIENVKVNNIYAMGEYFSIMTSKDTYEASKVILAMGMEHTKPLKGEDKFLVGYSATCDAPLYKGKIVTIVGYNKEAESEANYLAELASKVYYVPRYKDEYQLVSAVEIVKDVPVEIVGDKKVEKLKLKSRELETDGVFVLKDSAPPEQLVPGLYVEDGHIKVNRKMETNIDGCYAAGDCTGKPYQYMKAVGEGQVAALNAVEKL 6gnd G 2.89 BS01 FAD G 1 G10 S11 G12 P13 A14 S34 L37 S38 K40 L43 A44 P45 V46 N49 V81 A108 M109 G254 D255 Y261 Q262 Y263 G11 S12 G13 P14 A15 S35 L38 S39 K41 L44 A45 P46 V47 N50 V82 A109 M110 G250 D251 Y257 Q258 Y259 Q97EM8 30510005 HMERYDIAIIGSGPAGLASAINAKTRNKSVIVFGSSDLSKKLTLAPVINNYLGFYGIRGAELQEKFKEHIDNMGIQIENVKVNNIYAMGEYFSIMTSKDTYEASKVILAMGMEHTKPLKGEDKFLGSATCDAPLYKGKIVTIVGYNKEAESEANYLAELASKVYYVPRYKDEYQLVSAVEIVKDVPVEIVGDKKVEKLKLKSRELETDGVFVLKDSAPPEQLVPGLYVEDGHIKVNRKMETNIDGCYAAGDCTGKPYQYMKAVGEGQVAALNAVEKLYTK 6gqi A 2.00 BS01 FAD A 1 I14 G15 G17 F18 G19 F38 E39 K40 G46 T47 W48 W50 N51 Y53 S58 D59 T60 Y65 T110 E111 V112 A142 L143 G144 S147 N388 M392 N436 L437 I9 G10 G12 F13 G14 F33 E34 K35 G41 T42 W43 W45 N46 Y48 S53 D54 T55 Y60 T105 E106 V107 A137 L138 G139 S142 N383 M387 N431 L432 1.14.13.22 A0A1L1QK40 TPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLLSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNLPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRG 6gqi A 2.00 BS02 NAP A 1 K57 D59 L146 P152 I184 G185 T186 G187 S188 T189 Q192 R209 T210 R329 L350 A379 T380 G381 F382 W492 K52 D54 L141 P147 I179 G180 T181 G182 S183 T184 Q187 R204 T205 R324 L345 A374 T375 G376 F377 W487 1.14.13.22 A0A1L1QK40 TPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLLSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNLPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRG 6gqi A 2.00 BS03 6NA A 1 L145 R329 F434 T435 L437 W492 F507 L140 R324 F429 T430 L432 W487 F502 1.14.13.22 A0A1L1QK40 TPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLLSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNLPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRG 6gqi B 2.00 BS02 NAP B 1 Y53 K57 S58 D59 L146 P152 I184 G185 T186 G187 S188 T189 Q192 R209 T210 K328 R329 L350 A379 T380 G381 F382 W492 Y48 K52 S53 D54 L141 P147 I179 G180 T181 G182 S183 T184 Q187 R204 T205 K323 R324 L345 A374 T375 G376 F377 W487 1.14.13.22 A0A1L1QK40 TPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLLSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNLPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRG 6gqi B 2.00 BS03 6NA B 1 L145 F279 R329 F434 T435 L437 W492 F507 L140 F274 R324 F429 T430 L432 W487 F502 1.14.13.22 A0A1L1QK40 TPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLLSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNLPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRG 6gqi B 2.00 BS04 6NA B 2 V246 R329 F434 F486 L509 V241 R324 F429 F481 L504 1.14.13.22 A0A1L1QK40 TPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLLSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNLPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRG 6h7b A 1.89 BS01 III B 1 G503 D504 F507 P519 K520 T522 G523 M524 L526 E527 E549 A550 V553 H557 G22 D23 F26 P38 K39 T41 G42 M43 L45 E46 E68 A69 V72 H76 E9AFX7 30476241 LPPITPQELESMSPQEQRAALGDRLFLKVYEIAPELAPKITGMFLEMKPKEAYELLNDQKRLEERVTEALCVLKAHQT 6h7b A 1.89 BS02 III D 1 R546 E549 V553 R65 E68 V72 E9AFX7 30476241 LPPITPQELESMSPQEQRAALGDRLFLKVYEIAPELAPKITGMFLEMKPKEAYELLNDQKRLEERVTEALCVLKAHQT 6h7b C 1.89 BS01 III B 1 R546 E549 R65 E68 E9AFX7 30476241 LPPITPQELESMSPQEQRAALGDRLFLKVYEIAPELAPKITGMFLEMKPKEAYELLNDQKRLEERVTEALCVLKAHQ 6hho A 3.49 BS01 G4W A 1 V31 I43 K45 M67 L70 V75 V76 L78 L90 M92 L129 V134 H136 I154 A155 D156 L157 L159 S161 F162 V21 I33 K35 M57 L60 V65 V66 L68 L80 M82 L119 V124 H126 I144 A145 D146 L147 L149 S151 F152 2.7.11.1 Q13546 30423296 NVIKMKSSDFLESAELDFGKVSLAFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE 6hl8 A 2.40 BS02 GUA A 1 M157 H160 D162 G163 Y165 F247 R311 M130 H133 D135 G136 Y138 F213 R277 P76621 30498244 QDYSGFTLTPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVAKILDDLCANQLQPLLLKTLLNRAEGALLINAVGVDDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDNYFRHPLARRPMRFAAKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYASNHYQTHQ 6hl8 B 2.40 BS02 GUA B 1 M157 D162 G163 Y165 F247 R311 M129 D134 G135 Y137 F214 R278 P76621 30498244 YSGFTLTPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVAKILDDLCANQLQPLLLKTLLNRAEGALLINAVGVDDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDNYFRHPLARRPMRFAAPPKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYASNHYQTHQ 6hpr A 1.70 BS01 ZN A 1 C571 C574 C592 C595 C16 C19 C37 C40 2.3.2.27 Q13490 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 6hpr A 1.70 BS02 ZN A 2 C586 H588 C602 C605 C31 H33 C47 C50 2.3.2.27 Q13490 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 6hqd A 1.80 BS01 HEM A 1 D71 F105 L106 H113 R117 L171 G259 G260 T263 S267 P305 R311 Y334 S362 F363 G364 H368 C370 G372 A376 D65 F99 L100 H107 R111 L165 G253 G254 T257 S261 P299 R305 Y328 S356 F357 G358 H362 C364 G366 A370 G3LGZ6 30398864 IDDAEIARSIALEDIDVSKPELFERDGLHPYFERLRREDPVHYCKASEYGPYWSITKFSDIVAIDTNHKVFSSDHTNGSFVLDDTTLNAVDGGIYLPNFLGMDPPKHDVHRMVVSPIVAPQNLLRFEATIRERTKRVLSELPIGEEFNWVDRVSIELTTMMLATLLDFPFDDRRKLTRWSDIITTRPGYGLVDSWEQRESELMECLAYFQRLYAERQAMPPKPDLISMLAHSPEMQDLTPTDFLGTLALLIVGGNDTTRSSMSGSAMACHLYPQEFDKVRNNRALLASVIPEVVRWQTPIAHMRRTALEDVEFRGKQIRKGDKVVMWYLSGNRDDEVIDRPMDFIADRPRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERYSRIEVCGEPVRVPSNLVHGYIDIPVRLHA 6hqd B 1.80 BS01 HEM B 1 D71 F105 L106 H113 R117 L171 G259 T263 T264 P305 R311 Y334 S362 F363 G364 H368 C370 G372 A376 D63 F97 L98 H105 R109 L163 G251 T255 T256 P297 R303 Y326 S354 F355 G356 H360 C362 G364 A368 G3LGZ6 30398864 DAEIARSIALEDIDVSKPELFERDGLHPYFERLRREDPVHYCKASEYGPYWSITKFSDIVAIDTNHKVFSSDHTNGSFVLDDTTLNAVDGGIYLPNFLGMDPPKHDVHRMVVSPIVAPQNLLRFEATIRERTKRVLSELPIGEEFNWVDRVSIELTTMMLATLLDFPFDDRRKLTRWSDIITTRPGYGLVDSWEQRESELMECLAYFQRLYAERQAMPPKPDLISMLAHSPEMQDLTPTDFLGTLALLIVGGNDTTRSSMSGSAMACHLYPQEFDKVRNNRALLASVIPEVVRWQTPIAHMRRTALEDVEFRGKQIRKGDKVVMWYLSGNRDDEVIDRPMDFIADRPRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERYSRIEVCGEPVRVPSNLVHGYIDIPVRLHA 6hqd C 1.80 BS01 HEM C 1 D71 F105 L106 H113 R117 G259 G260 T263 T264 S267 P305 R311 Y334 S362 F363 G364 F365 I367 H368 C370 G372 A376 D66 F100 L101 H108 R112 G254 G255 T258 T259 S262 P300 R306 Y329 S357 F358 G359 F360 I362 H363 C365 G367 A371 G3LGZ6 30398864 PIDDAEIARSIALEDIDVSKPELFERDGLHPYFERLRREDPVHYCKASEYGPYWSITKFSDIVAIDTNHKVFSSDHTNGSFVLDDTTLNAVDGGIYLPNFLGMDPPKHDVHRMVVSPIVAPQNLLRFEATIRERTKRVLSELPIGEEFNWVDRVSIELTTMMLATLLDFPFDDRRKLTRWSDIITTRPGYGLVDSWEQRESELMECLAYFQRLYAERQAMPPKPDLISMLAHSPEMQDLTPTDFLGTLALLIVGGNDTTRSSMSGSAMACHLYPQEFDKVRNNRALLASVIPEVVRWQTPIAHMRRTALEDVEFRGKQIRKGDKVVMWYLSGNRDDEVIDRPMDFIADRPRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERYSRIEVCGEPVRVPSNLVHGYIDIPVRLHA 6hqg A 2.90 BS01 HEM A 1 D76 F102 I103 H110 R114 L259 G262 G263 T266 T270 I303 P308 L309 M312 R314 Y337 S365 F366 G367 H371 C373 V374 G375 L378 A379 D70 F96 I97 H104 R108 L197 G200 G201 T204 T208 I241 P246 L247 M250 R252 Y275 S303 F304 G305 H309 C311 V312 G313 L316 A317 B4RGA3 30398864 DLQRAARDAAYSMPIEEINPADPELFRTDTMWPYFERLRKEDPVHWGVSPHEDVGGYWSVTKYNDIMAVDTNHEVFSSEPTIVLPDPADDFTLPMFIAMDPPKHDVQRKTVQPIVAPNHLAYLEPIIRERAGKILDDLPIGEEINWVDKVSIELTTMTLATLFDFPWNLRRQTLFECVDYFMRLWNEMEYLGNLILLIVGGNDTTRNTISGSVLALHQNPDQDRKLRENPGLIPAMVSETIRWQTPLAYMRRRAKRDFELGGKTIREGDKVAMWYVSGNRDEEVIDRPNDYWIERPRVRQHLSFGFGVHRCVGNRLAELQLKIIWEEILARFPRLEVVGPPRRVYSSFVKGYEELPVVIPTRN 6hqg C 2.90 BS01 HEM C 1 D76 F102 I103 H110 R114 L258 L259 G262 G263 T266 T270 P308 L309 M312 R314 Y337 S365 F366 G367 F368 H371 C373 V374 G375 L378 A379 D70 F94 I95 H102 R106 L195 L196 G199 G200 T203 T207 P245 L246 M249 R251 Y274 S302 F303 G304 F305 H308 C310 V311 G312 L315 A316 B4RGA3 30398864 DLQRAARDAAYSMPIEEINPADPELFRTDTMWPYFERLRKEDPVHWGVSPHEDVGGYWSVTKYNDIMAVDTNHEVFSSEPTIVLPDPADTLPMFIAMDPPKHDVQRKTVQPIVAPNHLAYLEPIIRERAGKILDDLPIGEEINWVDKVSIELTTMTLATLFDFPWENLRRQTLFECVDYFMRLWNEMEYLGNLILLIVGGNDTTRNTISGSVLALHQNPDQDRKLRENPGLIPAMVSETIRWQTPLAYMRRRAKRDFELGGKTIREGDKVAMWYVSGNRDEEVIDRPNDYWIERPRVRQHLSFGFGVHRCVGNRLAELQLKIIWEEILARFPRLEVVGPPRRVYSSFVKGYEELPVVIPTRN 6hqw A 2.90 BS01 HEM A 1 E92 F129 I130 H137 R141 F148 G283 G284 T287 T291 P329 M333 R335 Y358 S386 F387 H392 C394 V395 G396 A400 E54 F91 I92 H99 R103 F110 G235 G236 T239 T243 P281 M285 R287 Y310 S338 F339 H344 C346 V347 G348 A352 Q2GBV5 30398864 SHPWDVSRSDIYVEDRWQPIFAEMRAKAPVNRVPDSPYGAYWNVASHKAIMHVESLPELFSSSWQYGGITIGDPPEDVDPQKLAERQLPMFIAMDRPDHTGQRRTVAPAFTPAKMVEMEAEIRRRTASVLDSLPWGERFDWVDKVSIELTTGMLAILFGFPWRLLTFWSDWAGLTLARELADTRFGFLGEMAHYFQRLWGARMQGDLISMMIHSEAMNHMSPQEFMGNLVLLIVGGNDTTRNTMSGIVHALDKFPDQRELLERDASLIPNAVQECIRYVTPLAHMRRTATADTELFGNQIKAGEKVILWYISANRDETVFENPDKLMVDRPNARRHLSFGHGIHRCVGARLAELQLRILLEEMHERRMRVRVAGEVERVRANFVHGFRKLEVELE 6hqw B 2.90 BS01 HEM B 1 E92 F129 I130 H137 R141 F148 L279 G283 G284 T287 T288 T291 L330 Y358 S386 F387 G388 H389 H392 C394 V395 G396 A400 E54 F72 I73 H80 R84 F91 L143 G147 G148 T151 T152 T155 L194 Y222 S250 F251 G252 H253 H256 C258 V259 G260 A264 Q2GBV5 30398864 SHPWDVSRSDIYVEDRWQPIFAEMRAKAPVNRVPDSPYGAYWNVASHKAIMHVESLPELFSSSWGGITIGMFIAMDRPDHTGQRRTVAPAFTPAKMVEMEAEIRRRTASVLDSLPWGERFDWVDKVSIELTTGMLAILGNLVLLIVGGNDTTRNTMSGIVHALDKFPDQRELLERDASLIPNAVQECIRYVTPLAHMRRTATADTELFGNQIKAGEKVILWYISANRDETVFENPDKLMVDRPNARRHLSFGHGIHRCVGARLAELQLRILLEEMHERRMRVRVAGEVERVRANFVHGFRKLEVELE 6hv8 A 4.40 BS01 ZN A 1 C2108 C2111 C2130 C2133 C667 C670 C683 C686 2.7.7.7 P21951 30498216 SMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKTSNPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEVLLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSSNDALNVLRGMLKEWWDEALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEASHLNVKNPLLELVKSLCHVMLLSKSTILEISLVVPDFLCEYCFFISDIDFCKFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLT 6hv8 A 4.40 BS02 ZN A 2 C2164 R2166 C2167 C2179 C2181 C717 R719 C720 C732 C734 2.7.7.7 P21951 30498216 SMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKTSNPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEVLLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSSNDALNVLRGMLKEWWDEALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEASHLNVKNPLLELVKSLCHVMLLSKSTILEISLVVPDFLCEYCFFISDIDFCKFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLT 6hv9 3 4.98 BS01 NUC Y 1 P228 I230 P152 I153 3.6.4.12 P24279 30498216 AVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQLIGFKTLILGNTVYPTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 6hv9 3 4.98 BS02 NUC J 1 A444 V446 R455 K499 A500 A348 V350 R355 K399 A400 3.6.4.12 P24279 30498216 AVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQLIGFKTLILGNTVYPTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 6hv9 3 4.98 BS03 AGS 5 1 S370 I371 S412 K415 S416 E474 S274 I275 S316 K319 S320 E374 3.6.4.12 P24279 30498216 AVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQLIGFKTLILGNTVYPTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 6hv9 5 4.98 BS01 AGS 5 2 P418 G419 T420 A421 K422 S423 N524 P308 G309 T310 A311 K312 S313 N412 3.6.4.12 P29496 30498216 DNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSNSLPTFQLILNDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNNTVSLPRSCLSTINCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKGVAIRTPYIKILGIQSDEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLASVQRPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQELKRRLPIGWSTSYQTLRREFVDHRFSQLALDKALYETIQLRHQGQNIYRSGV 6hv9 5 4.98 BS02 AGS 5 1 H494 Q499 R549 I650 R651 H382 Q387 R437 I531 R532 3.6.4.12 P29496 30498216 DNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSNSLPTFQLILNDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNNTVSLPRSCLSTINCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKGVAIRTPYIKILGIQSDEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLASVQRPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQELKRRLPIGWSTSYQTLRREFVDHRFSQLALDKALYETIQLRHQGQNIYRSGV 6hv9 2 4.98 BS01 NUC J 1 S579 V580 R581 K633 S328 V329 R330 K373 3.6.4.12 P29469 30498216 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRIESNLSSLVRVTGVVTRRTGVFPQLKYVKFLKCGSILGPFFQDSNEEIRIPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNFATIIEANSIKRRETEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASVGLTASVRKEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 6hv9 2 4.98 BS02 AGS 5 3 I533 R534 H621 R676 R808 I283 R284 H361 R415 R493 3.6.4.12 P29469 30498216 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRIESNLSSLVRVTGVVTRRTGVFPQLKYVKFLKCGSILGPFFQDSNEEIRIPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNFATIIEANSIKRRETEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASVGLTASVRKEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 6hyp A 4.40 BS01 ADP A 1 F288 G318 G320 K321 T322 F323 F241 G271 G273 K274 T275 F276 Q12019 30460895 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGPSVPECFTIEKKSSYFIIEPQDLSTKVASICGVIVPKVHTIHDKVFYPLTFVPTHKTVSSLRQLGRKIQNSTPIMLIGKAGSGKTFLINELSKYMGCHDSIVKIHLGEQTDAKLLIGTYTSFEWRAGVLATAVKEGRWVLIEDIDKAPTDVLSILLSLLEKRELTIPSRGETVKAANGFQLISTVRNLNMIGMRIWNVIELEEPSEEDLTHILAQKFPILTNLIPKLIDSYKNVKSIYMNTKFISLNKGAHTRVVSVRDLIKLCERLDILFKNNGINKPDQLIQSSVYDSIFSEAADCFAGAIGEFKALEPIIQAIGESLTQHVPTLENLDDSIKIGRAVLMNSTLFAFTNHSLRLMEQISVCIQMTEPVLLVGETGTGKTTVVQQLAKMLAKKLTVINVSQQTETGDLLGGYKPVNSKTVAVPIQENFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNVVKLWNEAYKLLDKWADFNDSVKKFEAQSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVNLATADTLESISDLLTEPDSRSILLSAEPIKAHPDFRIFACMNPATDVGKRDLPMGIRSRFTEIYVHSPERDITDLLSIIDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVTDIIHIYGLRRSLYDGFCMSFLTLLDQKSEAILKPVIEKFTLGRLKNVKSIMSQTPPSPGPDYQAHYIITPFVEKNMMNLVRATSGKRFPVLIQGPTSSGKTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYVTDDTGKLSFKEGVLVEALRKGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHPDFLLFATQNPPGIYGGRKILSRAFRNRFLELHFDDIPQDELEIILRERCQIAPSYAKKIVERLFEQKNSFATLRDLFRWAVGYEQLAASGYMLLAERCRTPQEKVTVKKTLEKVMKLEAIGSVTWTKGMRRLSVLVSSCLKNKEPVLLVGETGCGKTTICQLLAQFMGRELITLNAHQNTETGDILGAQEWSDGPLIQAMRTGNFFLLDEISLADDSVLERLNSVLEPERSLLLAESDSLVTASENFQFFATMNPGGDYGKKELSPALRNRFTEIWVPSMEDFNDVNMIVSSRLLEDLKDLANPIVKFSEWFGKNATSGVISLRDILAWVEFINKVFPKIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSLFNLTAPTTASNLVRVVRAMQVHKPILLEGSPGVGKTSLITALANITGNKLTRINLSEQTDLVDLFGAHDAPFLRAMKKGEWVLLDEMNLASQSVLEGLNACLDHRGEAYIISFSCHPNFLVFAAQNPKGLPKSFVNRFSVVFIDMLTSDDLLLIAKHLYPSIEPDIIAKMIKLMSTLEDQVCKRKLWGNSGSPWEFNLRDTLRWLKLLNQYSICEDVDVFDFVDIIVKQRFRTISDKNKAQLLIEDIFGKFSTKENFFKLTEDYVQINNEVALRNPHYRYPITQNLFPLECNVAVYESVLKAINNNWPLVLVGPSNSGKTETIRFLASILGPRVDVFSMNSDIDSMDILGGYEQVDLTRQISYITEELTNIVREIISMNMKLSPNATAIMEGLNLLKYLLNNIVTPEKFQDFRNRFNRFFSHLEGHPLLKTMSMNIEKMTEIITKEASVKFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLIQPRVLKPHPNFRLFLTMDPKYGELSRAMRNRGVEIYIDELHSRSTAFDRLTLGFPDMSIPLKHYVPSYLSRPCIFAQVHDILLLSDEEPIEESLAAVIPISHLGEVGKWANNVLNCTEYSEKKIAERLYVFITFLTDMGVLEKINNLYKPANLKFQKALGLHDKQLTEETVSLTLNEYVLPTVSKYSDKIKSPESLYLLSSLRLLLNSLNALKLINEKSTHGKIDELTYIELSAAAFIFCILYNILTVMSENLKTESLFCGSNQYQYYWDLLVIVIAALETAVTKDEARLRVYKELIDSWIASVKSKSDAIHDYVLYDLFLKTKTFSQNLMKSWRNVRKVISGDEEIFTEKLINT 6hyp A 4.40 BS02 ADP A 2 F2028 N2057 S2058 G2059 K2060 T2061 E2062 F1708 N1737 S1738 G1739 K1740 T1741 E1742 Q12019 30460895 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGPSVPECFTIEKKSSYFIIEPQDLSTKVASICGVIVPKVHTIHDKVFYPLTFVPTHKTVSSLRQLGRKIQNSTPIMLIGKAGSGKTFLINELSKYMGCHDSIVKIHLGEQTDAKLLIGTYTSFEWRAGVLATAVKEGRWVLIEDIDKAPTDVLSILLSLLEKRELTIPSRGETVKAANGFQLISTVRNLNMIGMRIWNVIELEEPSEEDLTHILAQKFPILTNLIPKLIDSYKNVKSIYMNTKFISLNKGAHTRVVSVRDLIKLCERLDILFKNNGINKPDQLIQSSVYDSIFSEAADCFAGAIGEFKALEPIIQAIGESLTQHVPTLENLDDSIKIGRAVLMNSTLFAFTNHSLRLMEQISVCIQMTEPVLLVGETGTGKTTVVQQLAKMLAKKLTVINVSQQTETGDLLGGYKPVNSKTVAVPIQENFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNVVKLWNEAYKLLDKWADFNDSVKKFEAQSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVNLATADTLESISDLLTEPDSRSILLSAEPIKAHPDFRIFACMNPATDVGKRDLPMGIRSRFTEIYVHSPERDITDLLSIIDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVTDIIHIYGLRRSLYDGFCMSFLTLLDQKSEAILKPVIEKFTLGRLKNVKSIMSQTPPSPGPDYQAHYIITPFVEKNMMNLVRATSGKRFPVLIQGPTSSGKTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYVTDDTGKLSFKEGVLVEALRKGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHPDFLLFATQNPPGIYGGRKILSRAFRNRFLELHFDDIPQDELEIILRERCQIAPSYAKKIVERLFEQKNSFATLRDLFRWAVGYEQLAASGYMLLAERCRTPQEKVTVKKTLEKVMKLEAIGSVTWTKGMRRLSVLVSSCLKNKEPVLLVGETGCGKTTICQLLAQFMGRELITLNAHQNTETGDILGAQEWSDGPLIQAMRTGNFFLLDEISLADDSVLERLNSVLEPERSLLLAESDSLVTASENFQFFATMNPGGDYGKKELSPALRNRFTEIWVPSMEDFNDVNMIVSSRLLEDLKDLANPIVKFSEWFGKNATSGVISLRDILAWVEFINKVFPKIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSLFNLTAPTTASNLVRVVRAMQVHKPILLEGSPGVGKTSLITALANITGNKLTRINLSEQTDLVDLFGAHDAPFLRAMKKGEWVLLDEMNLASQSVLEGLNACLDHRGEAYIISFSCHPNFLVFAAQNPKGLPKSFVNRFSVVFIDMLTSDDLLLIAKHLYPSIEPDIIAKMIKLMSTLEDQVCKRKLWGNSGSPWEFNLRDTLRWLKLLNQYSICEDVDVFDFVDIIVKQRFRTISDKNKAQLLIEDIFGKFSTKENFFKLTEDYVQINNEVALRNPHYRYPITQNLFPLECNVAVYESVLKAINNNWPLVLVGPSNSGKTETIRFLASILGPRVDVFSMNSDIDSMDILGGYEQVDLTRQISYITEELTNIVREIISMNMKLSPNATAIMEGLNLLKYLLNNIVTPEKFQDFRNRFNRFFSHLEGHPLLKTMSMNIEKMTEIITKEASVKFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLIQPRVLKPHPNFRLFLTMDPKYGELSRAMRNRGVEIYIDELHSRSTAFDRLTLGFPDMSIPLKHYVPSYLSRPCIFAQVHDILLLSDEEPIEESLAAVIPISHLGEVGKWANNVLNCTEYSEKKIAERLYVFITFLTDMGVLEKINNLYKPANLKFQKALGLHDKQLTEETVSLTLNEYVLPTVSKYSDKIKSPESLYLLSSLRLLLNSLNALKLINEKSTHGKIDELTYIELSAAAFIFCILYNILTVMSENLKTESLFCGSNQYQYYWDLLVIVIAALETAVTKDEARLRVYKELIDSWIASVKSKSDAIHDYVLYDLFLKTKTFSQNLMKSWRNVRKVISGDEEIFTEKLINT 6i2y A 2.56 BS01 88Z A 1 L42 V50 A63 L85 V94 I108 I110 E111 C113 P114 L148 H155 L164 L173 A174 D175 F176 L19 V27 A40 L62 V71 I85 I87 E88 C90 P91 L125 H132 L141 L150 A151 D152 F153 2.7.11.1 O94804 EHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNIGTPYWMAPEVVMCEPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLAIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 6i2y B 2.56 BS01 88Z B 1 L42 V50 A63 L85 I93 V94 I108 I110 E111 F112 C113 P114 G116 L148 H155 L164 L173 A174 D175 F176 V314 L19 V27 A40 L60 I68 V69 I82 I84 E85 F86 C87 P88 G90 L122 H129 L138 L147 A148 D149 F150 V274 2.7.11.1 O94804 EHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNIGTPYWMAPEVVMCETPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLAIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 6ifk A 3.20 BS01 NUC N 1 E400 H405 E377 H382 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk A 3.20 BS02 NUC J 1 A261 T262 N263 G264 A265 H414 Y496 K511 R512 K619 P621 I622 E679 R680 G681 K682 N683 Y686 Y705 Y706 R709 R756 A241 T242 N243 G244 A245 H391 Y473 K488 R489 K596 P598 I599 E656 R657 G658 K659 N660 Y663 Y682 Y683 R686 R733 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk A 3.20 BS03 ANP A 1 Y300 H305 D519 V520 D521 D522 L523 G524 F527 S549 M552 G576 D577 K637 K641 Y280 H285 D496 V497 D498 D499 L500 G501 F504 S526 M529 G553 D554 K614 K618 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk A 3.20 BS04 ANP A 2 D247 L248 I251 Q252 I255 S273 G303 K378 Y573 D578 D227 L228 I231 Q232 I235 S253 G283 K355 Y550 D555 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk A 3.20 BS05 MG A 1 D519 V520 D577 K637 D496 V497 D554 K614 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk A 3.20 BS06 MG A 2 D519 D577 D496 D554 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk A 3.20 BS07 ZN A 1 C401 C404 C419 C422 C378 C381 C396 C399 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifk D 3.20 BS01 NUC J 1 T36 T37 S38 K39 R41 Y75 R79 K120 T34 T35 S36 K37 R39 Y73 R77 K118 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ifk G 3.20 BS01 NUC N 1 G21 S50 S51 K53 G54 K55 R57 T58 G84 N85 S86 K92 M93 F122 E123 N124 T125 I126 R128 A133 P135 R136 Y181 G183 G184 S185 S187 R188 G20 S49 S50 K52 G53 K54 R56 T57 G83 N84 S85 K91 M92 F121 E122 N123 T124 I125 R127 A132 P134 R135 Y180 G182 G183 S184 S186 R187 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifk G 3.20 BS02 NUC J 1 I29 N33 A133 N134 P135 R136 Q137 I28 N32 A132 N133 P134 R135 Q136 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifk F 3.20 BS01 NUC N 1 I20 G21 G22 D24 S50 S51 K53 G54 K55 R57 T58 F83 G84 S86 K92 E123 N124 T125 I126 A133 P135 R136 Y181 G184 S187 R188 I19 G20 G21 D23 S49 S50 K52 G53 K54 R56 T57 F82 G83 S85 K91 E122 N123 T124 I125 A132 P134 R135 Y180 G183 S186 R187 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifk F 3.20 BS02 NUC J 1 D24 I29 N33 S86 K87 A133 N134 P135 R136 D23 I28 N32 S85 K86 A132 N133 P134 R135 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifk E 3.20 BS01 NUC N 1 G21 G22 S50 S51 K53 G54 K55 R57 G84 N85 S86 M93 F122 E123 N124 T125 I126 A133 R136 Y181 G183 G184 S185 S187 R188 G20 G21 S49 S50 K52 G53 K54 R56 G74 N75 S76 M83 F112 E113 N114 T115 I116 A123 R126 Y171 G173 G174 S175 S177 R178 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNESDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifk E 3.20 BS02 NUC J 1 I29 N33 E132 A133 N134 P135 R136 I28 N32 E122 A123 N124 P125 R126 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNESDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifk B 3.20 BS01 NUC N 1 H14 G16 G18 T19 R31 F33 S34 A35 V37 L38 L46 T132 K133 N134 Q135 P136 L142 Y143 G177 L178 G179 G180 K181 R182 S183 S240 G241 F242 A243 F244 N251 R253 H284 A285 V286 L287 N288 H13 G15 G17 T18 R30 F32 S33 A34 V36 L37 L45 T128 K129 N130 Q131 P132 L138 Y139 G173 L174 G175 G176 K177 R178 S179 S236 G237 F238 A239 F240 N247 R249 H280 A281 V282 L283 N284 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKLEV 6ifk B 3.20 BS02 NUC J 1 K138 D139 D140 N141 L142 K134 D135 D136 N137 L138 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKLEV 6ifk H 3.20 BS01 NUC N 1 I20 G21 G23 S130 S131 K133 G134 A135 R137 T138 W169 D179 F181 N182 K202 D204 P214 L215 Y279 G281 A282 G283 G285 A286 T288 K289 Y303 M306 K307 T308 K309 G314 V315 K317 I18 G19 G21 S128 S129 K131 G132 A133 R135 T136 W167 D177 F179 N180 K200 D202 P212 L213 Y277 G279 A280 G281 G283 A284 T286 K287 Y301 M304 K305 T306 K307 G312 V313 K315 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI 6ifk H 3.20 BS02 NUC J 1 S28 N69 A70 N73 R74 N112 E113 W169 P216 L217 R305 K307 S26 N67 A68 N71 R72 N110 E111 W167 P214 L215 R303 K305 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI 6ifl A 3.16 BS01 NUC J 1 R512 K619 P621 E679 R680 G681 K682 N683 Y686 Y705 Y706 R709 R756 R445 K552 P554 E612 R613 G614 K615 N616 Y619 Y638 Y639 R642 R689 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMADHLAYITYIADNIASGYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRKD 6ifl B 3.16 BS01 NUC J 1 T36 T37 S38 K39 R41 R79 K120 T34 T35 S36 K37 R39 R77 K118 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ifl C 3.16 BS01 NUC J 1 T36 T37 S38 K39 R41 Y75 R79 T34 T35 S36 K37 R39 Y73 R77 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ifl D 3.16 BS01 NUC I 1 H19 I20 G21 S50 S51 K53 G54 K55 R57 T58 F83 G84 S86 K87 K92 K121 F122 E123 N124 T125 I126 R128 A133 P135 R136 Y181 G184 S187 R188 H18 I19 G20 S49 S50 K52 G53 K54 R56 T57 F82 G83 S85 K86 K91 K120 F121 E122 N123 T124 I125 R127 A132 P134 R135 Y180 G183 S186 R187 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifl D 3.16 BS02 NUC J 1 G30 N33 K87 T125 A133 N134 P135 R136 G29 N32 K86 T124 A132 N133 P134 R135 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifl E 3.16 BS01 NUC I 1 H19 G21 G22 D24 S50 S51 K53 G54 K55 R57 T58 P72 F83 G84 S86 K92 M93 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 H19 G21 G22 D24 S50 S51 K53 G54 K55 R57 T58 P72 F83 G84 S86 K92 M93 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifl E 3.16 BS02 NUC J 1 I29 N33 K87 A133 N134 P135 R136 Q137 I29 N33 K87 A133 N134 P135 R136 Q137 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifl F 3.16 BS01 NUC I 1 I20 G21 G22 D24 S50 S51 K53 G54 K55 R57 T58 F83 G84 S86 M93 F122 E123 N124 T125 I126 A133 R136 Y181 G183 G184 S187 R188 I19 G20 G21 D23 S49 S50 K52 G53 K54 R56 T57 F71 G72 S74 M81 F110 E111 N112 T113 I114 A121 R124 Y169 G171 G172 S175 R176 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifl F 3.16 BS02 NUC J 1 A28 I29 N33 E132 A133 N134 P135 R136 A27 I28 N32 E120 A121 N122 P123 R124 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifl G 3.16 BS01 NUC I 1 H14 G16 S17 G18 L20 R31 F33 S34 A35 V37 L38 L46 T132 K133 N134 Q135 P136 N141 L142 Y143 L178 G179 G180 K181 R182 S183 K238 S240 G241 F242 A243 F244 N251 K254 H284 A285 L287 H13 G15 S16 G17 L19 R30 F32 S33 A34 V36 L37 L45 T108 K109 N110 Q111 P112 N117 L118 Y119 L154 G155 G156 K157 R158 S159 K214 S216 G217 F218 A219 F220 N227 K230 H260 A261 L263 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifl G 3.16 BS02 NUC J 1 L20 D139 D140 N141 L142 Y143 F242 E250 N251 Y252 R253 L19 D115 D116 N117 L118 Y119 F218 E226 N227 Y228 R229 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifl H 3.16 BS01 NUC I 1 I20 G21 G23 S130 S131 K133 G134 R137 T138 W169 Y177 D179 F181 N182 K202 D204 P214 L215 L217 Y279 G281 A282 G283 S284 G285 A286 T288 K289 Y303 M306 K307 T308 K309 M310 V315 K317 I18 G19 G21 S123 S124 K126 G127 R130 T131 W162 Y170 D172 F174 N175 K195 D197 P207 L208 L210 Y272 G274 A275 G276 S277 G278 A279 T281 K282 Y296 M299 K300 T301 K302 M303 V308 K310 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTVKIPSGNHSLVKNHESFYEMGKANFMIKEI 6ifl H 3.16 BS02 NUC J 1 P68 N69 A70 R74 N112 E113 W169 P216 L217 R305 K307 P66 N67 A68 R72 N105 E106 W162 P209 L210 R298 K300 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTVKIPSGNHSLVKNHESFYEMGKANFMIKEI 6ifn A 2.90 BS03 MN A 1 D16 K19 H31 H55 D16 K19 H31 H55 A0A2U2M0F3 MKKEKIDLFYGALLHDIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMADKLGNDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifn F 2.90 BS01 NUC N 1 I20 G21 G22 S50 S51 K53 G54 K55 R57 S86 K92 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 I20 G21 G22 S50 S51 K53 G54 K55 R57 S86 K92 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAIDSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTAEV 6ifn B 2.90 BS01 NUC N 1 H14 G16 S17 G18 T19 R31 S34 A35 V37 L38 L41 L46 T132 K133 N134 Q135 P136 N141 L142 Y143 G177 L178 G179 G180 K181 R182 S183 S240 F242 A243 F244 N251 R253 K254 H284 A285 V286 L287 H13 G15 S16 G17 T18 R30 S33 A34 V36 L37 L40 L45 T131 K132 N133 Q134 P135 N140 L141 Y142 G176 L177 G178 G179 K180 R181 S182 S239 F241 A242 F243 N250 R252 K253 H283 A284 V285 L286 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHDQIDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKLE 6ifn E 2.90 BS01 NUC N 1 I20 S23 S50 S51 K53 G54 K55 R57 T58 G84 S86 K92 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 I20 S23 S50 S51 K53 G54 K55 R57 T58 G84 S86 K92 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAIDSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTAE 6ifn G 2.90 BS01 NUC N 1 H19 I20 S50 S51 K53 G54 R57 F83 G84 S86 K92 M93 F122 E123 N124 T125 I126 R128 A133 P135 R136 Y181 G183 G184 S187 R188 H19 I20 S50 S51 K53 G54 R57 F83 G84 S86 K92 M93 F122 E123 N124 T125 I126 R128 A133 P135 R136 Y181 G183 G184 S187 R188 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAIDSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTAEV 6ifn H 2.90 BS01 NUC N 1 I20 G21 G23 S130 S131 K133 G134 A135 R137 T138 W169 P171 Y177 D179 F181 N182 D204 L215 Y279 G281 A282 G283 G285 A286 T288 K289 R302 Y303 M306 K307 T308 K309 V315 K317 I18 G19 G21 S121 S122 K124 G125 A126 R128 T129 W157 P159 Y165 D167 F169 N170 D192 L203 Y267 G269 A270 G271 G273 A274 T276 K277 R290 Y291 M294 K295 T296 K297 V303 K305 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNNNRLISFLNDNRIAERSFGGYSISETGLESDKNAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTVKIPSGNHSLVKNHESFYEMGKANFMIKEIDK 6ifr A 3.40 BS02 ATP A 1 D247 I251 Q252 I255 S273 D277 G303 K378 Y573 D216 I220 Q221 I224 S236 D240 G266 K341 Y509 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMADHLAYITYIADNIASGYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNIAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRKD 6ifr A 3.40 BS03 ATP A 2 Y300 D519 V520 D521 L523 S549 S553 G576 D577 K637 K641 Y263 D455 V456 D457 L459 S485 S489 G512 D513 K573 K577 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMADHLAYITYIADNIASGYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNIAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRKD 6ifr A 3.40 BS04 MG A 1 V520 D521 D577 V456 D457 D513 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMADHLAYITYIADNIASGYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNIAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRKD 6ifr A 3.40 BS05 MG A 2 D519 D577 D455 D513 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMADHLAYITYIADNIASGYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNIAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRKD 6ifr D 3.40 BS01 NUC J 1 T36 T37 S38 K39 R41 R79 E80 K120 T34 T35 S36 K37 R39 R77 E78 K118 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ifr G 3.40 BS01 NUC N 1 H19 I20 G21 S50 S51 K53 G54 K55 R57 T58 G84 S86 K92 M93 F122 E123 N124 T125 I126 R128 A133 P135 R136 Y181 G184 S185 G186 S187 R188 H18 I19 G20 S49 S50 K52 G53 K54 R56 T57 G83 S85 K91 M92 F121 E122 N123 T124 I125 R127 A132 P134 R135 Y180 G183 S184 G185 S186 R187 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifr G 3.40 BS02 NUC J 1 G30 N33 K87 A133 N134 P135 R136 G29 N32 K86 A132 N133 P134 R135 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifr F 3.40 BS01 NUC N 1 G21 G22 D24 S50 S51 K53 G54 K55 R57 T58 F83 G84 S86 K92 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S185 S187 R188 G21 G22 D24 S50 S51 K53 G54 K55 R57 T58 F83 G84 S86 K92 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S185 S187 R188 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifr F 3.40 BS02 NUC J 1 I29 N33 K87 A133 N134 P135 R136 I29 N33 K87 A133 N134 P135 R136 A0A2U2M035 MTFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifr E 3.40 BS01 NUC N 1 I20 G21 D24 S50 S51 K53 G54 K55 R57 T58 F83 G84 N85 S86 M93 F122 E123 N124 T125 I126 A133 R136 Y181 G183 G184 S185 G186 S187 R188 I19 G20 D23 S49 S50 K52 G53 K54 R56 T57 F71 G72 N73 S74 M81 F110 E111 N112 T113 I114 A121 R124 Y169 G171 G172 S173 G174 S175 R176 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifr E 3.40 BS02 NUC J 1 I29 N33 K87 E132 A133 N134 P135 R136 I28 N32 K75 E120 A121 N122 P123 R124 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifr B 3.40 BS01 NUC N 1 H14 F15 G16 S17 G18 T19 D30 R31 F33 S34 A35 V37 L38 T132 K133 N134 Q135 P136 N141 L142 Y143 G177 L178 G179 G180 K181 R182 S183 S240 G241 F242 A243 F244 N251 R253 K254 H284 A285 V286 L287 H13 F14 G15 S16 G17 T18 D29 R30 F32 S33 A34 V36 L37 T123 K124 N125 Q126 P127 N132 L133 Y134 G168 L169 G170 G171 K172 R173 S174 S231 G232 F233 A234 F235 N242 R244 K245 H275 A276 V277 L278 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifr B 3.40 BS02 NUC J 1 D139 D140 N141 L142 Y143 F242 E250 N251 Y252 R253 D130 D131 N132 L133 Y134 F233 E241 N242 Y243 R244 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifr B 3.40 BS03 ATP A 3 R94 K98 R85 K89 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifr H 3.40 BS01 NUC N 1 G21 G23 S130 S131 K133 G134 A135 R137 T138 W169 Y177 D179 F181 N182 K202 D204 K213 P214 L215 Y279 L280 G281 A282 G283 G285 A286 T288 K289 Y303 K307 T308 K309 M310 V315 K317 G19 G21 S128 S129 K131 G132 A133 R135 T136 W167 Y175 D177 F179 N180 K200 D202 K211 P212 L213 Y277 L278 G279 A280 G281 G283 A284 T286 K287 Y301 K305 T306 K307 M308 V313 K315 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTVKIPSGNHSLVKNHESFYEMGKANFMIKEI 6ifr H 3.40 BS02 NUC J 1 P68 A70 R74 N112 E113 W169 P216 L217 K307 P66 A68 R72 N110 E111 W167 P214 L215 K305 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTVKIPSGNHSLVKNHESFYEMGKANFMIKEI 6ifu A 3.60 BS02 NUC J 1 R512 D618 E679 R680 G681 K682 N683 Y686 K687 Y705 Y706 R709 L710 E712 R756 K757 R461 D567 E628 R629 G630 K631 N632 Y635 K636 Y654 Y655 R658 L659 E661 R705 K706 A0A2U2M0F3 KKEKIDLFYGALLADIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMLAYITYIADNIASGYTNQADIFNVFGAQKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifu D 3.60 BS02 NUC J 1 I29 N33 A133 N134 P135 R136 I28 N32 A132 N133 P134 R135 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ifu E 3.60 BS02 NUC J 1 D24 I29 N33 S86 K87 A133 N134 P135 R136 Q137 D23 I28 N32 S85 K86 A132 N133 P134 R135 Q136 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifu G 3.60 BS01 NUC I 1 H14 G16 S17 G18 D30 R31 S34 A35 V37 L38 L46 T132 K133 N134 Q135 P136 H137 L142 Y143 G177 L178 G179 G180 K181 R182 S183 S240 G241 F242 A243 F244 N251 R253 K254 H284 A285 V286 L287 N288 H13 G15 S16 G17 D29 R30 S33 A34 V36 L37 L45 T107 K108 N109 Q110 P111 H112 L117 Y118 G152 L153 G154 G155 K156 R157 S158 S215 G216 F217 A218 F219 N226 R228 K229 H259 A260 V261 L262 N263 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifu G 3.60 BS02 NUC J 1 K138 D139 N141 K113 D114 N116 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ify A 3.80 BS02 NUC J 1 I510 R512 K619 E679 R680 G681 K682 N683 Y686 Y705 Y706 R709 L710 E712 R756 K757 I486 R488 K595 E655 R656 G657 K658 N659 Y662 Y681 Y682 R685 L686 E688 R732 K733 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ify A 3.80 BS03 ZN A 1 C401 I403 C404 C422 C377 I379 C380 C398 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ify C 3.80 BS01 NUC J 1 T36 T37 S38 K39 R41 N42 Y75 Q76 R79 K120 T34 T35 S36 K37 R39 N40 Y73 Q74 R77 K118 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ify G 3.80 BS01 NUC I 1 H19 I20 G21 S50 S51 K53 G54 K55 R57 F83 N85 S86 K92 M93 F122 E123 N124 T125 I126 R128 A133 P135 R136 Y181 G183 G184 S185 S187 R188 H18 I19 G20 S49 S50 K52 G53 K54 R56 F82 N84 S85 K91 M92 F121 E122 N123 T124 I125 R127 A132 P134 R135 Y180 G182 G183 S184 S186 R187 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ify G 3.80 BS02 NUC J 1 I29 N33 S34 A133 N134 P135 R136 I28 N32 S33 A132 N133 P134 R135 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLTA 6ify F 3.80 BS02 NUC J 1 I29 N33 S86 K87 E132 A133 N134 P135 R136 I28 N32 S85 K86 E131 A132 N133 P134 R135 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ify E 3.80 BS01 NUC I 1 I20 G21 S50 S51 K53 G54 K55 R57 T58 G84 N85 S86 F122 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S185 S187 R188 I19 G20 S49 S50 K52 G53 K54 R56 T57 G73 N74 S75 F111 E112 N113 T114 I115 A122 P124 R125 Y170 G172 G173 S174 S176 R177 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ify B 3.80 BS01 NUC I 1 H14 G16 G18 T19 D30 R31 S34 A35 V37 L41 L46 K133 N134 Q135 P136 N141 L142 Y143 G180 R182 S183 S240 G241 F242 A243 F244 N251 R253 K254 H284 A285 V286 L287 N288 H13 G15 G17 T18 D29 R30 S33 A34 V36 L40 L45 K128 N129 Q130 P131 N136 L137 Y138 G175 R177 S178 S235 G236 F237 A238 F239 N246 R248 K249 H279 A280 V281 L282 N283 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKLEV 6ify H 3.80 BS01 NUC I 1 I20 G21 G23 S130 S131 K133 G134 A135 T138 W169 G170 D179 N182 P214 L215 G281 A282 G283 S284 G285 A286 T288 K289 Y303 K307 T308 K309 G314 V315 K317 I18 G19 G21 S128 S129 K131 G132 A133 T136 W167 G168 D177 N180 P212 L213 G279 A280 G281 S282 G283 A284 T286 K287 Y301 K305 T306 K307 G312 V313 K315 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI 6ify H 3.80 BS02 NUC J 1 S28 A70 N73 R74 K103 N112 E113 L215 P216 L217 R305 K307 S26 A68 N71 R72 K101 N110 E111 L213 P214 L215 R303 K305 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI 6ifz A 3.58 BS02 NUC J 1 R512 E679 R680 G681 K682 N683 Y686 Y705 Y706 R709 R756 K757 R489 E656 R657 G658 K659 N660 Y663 Y682 Y683 R686 R733 K734 A0A2U2M0F3 KKEKIDLFYGALLADIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifz A 3.58 BS03 ZN A 1 C404 C419 C422 C381 C396 C399 A0A2U2M0F3 KKEKIDLFYGALLADIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ifz D 3.58 BS01 NUC J 1 T36 S38 K39 R41 Y75 R79 K120 T34 S36 K37 R39 Y73 R77 K118 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ifz C 3.58 BS01 NUC J 1 T36 T37 S38 K39 R41 N42 Y75 R79 K120 T34 T35 S36 K37 R39 N40 Y73 R77 K118 A0A2U2M049 ILTDENYVDIAEKAILKLERNTRNRKNPDAFFLTTSKLRNLLSLTSTLFDESKVKEYDALLDRIAYLRVQFVYQAGREIAVKDLIEKAQILEALKEIKDRETLQRFCRYMEALVAYFKFYG 6ifz F 3.58 BS01 NUC I 1 G21 G22 D24 S50 S51 K53 G54 K55 R57 P72 G84 S86 K92 M93 E123 N124 T125 I126 A133 P135 R136 Y181 G183 G184 S187 R188 G20 G21 D23 S49 S50 K52 G53 K54 R56 P71 G83 S85 K91 M92 E122 N123 T124 I125 A132 P134 R135 Y180 G182 G183 S186 R187 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifz E 3.58 BS01 NUC I 1 I20 G21 S50 S51 K53 G54 K55 R57 S86 F122 E123 N124 T125 I126 A133 R136 Y181 G184 S185 G186 S187 R188 I19 G20 S49 S50 K52 G53 K54 R56 S76 F112 E113 N114 T115 I116 A123 R126 Y171 G174 S175 G176 S177 R178 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNESDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifz E 3.58 BS02 NUC J 1 N33 E132 A133 N134 P135 R136 N32 E122 A123 N124 P125 R126 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNESDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ifz B 3.58 BS01 NUC I 1 H14 G16 G18 T19 L20 D30 R31 S34 A35 V37 L38 L41 L46 T132 K133 N134 Q135 P136 H137 L142 Y143 G177 G180 K181 R182 S183 S240 G241 F242 A243 F244 N251 R253 K254 H284 A285 V286 L287 N288 H13 G15 G17 T18 L19 D29 R30 S33 A34 V36 L37 L40 L45 T128 K129 N130 Q131 P132 H133 L138 Y139 G173 G176 K177 R178 S179 S236 G237 F238 A239 F240 N247 R249 K250 H280 A281 V282 L283 N284 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifz B 3.58 BS02 NUC J 1 K138 D139 N141 K134 D135 N137 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKL 6ifz H 3.58 BS01 NUC I 1 I20 G21 N22 G23 S130 S131 K133 G134 R137 T138 W169 Y177 D179 N182 K202 P214 L215 P216 Y279 G281 A282 G283 G285 A286 T288 K289 Y303 K307 T308 V315 K317 I18 G19 N20 G21 S128 S129 K131 G132 R135 T136 W167 Y175 D177 N180 K200 P212 L213 P214 Y277 G279 A280 G281 G283 A284 T286 K287 Y301 K305 T306 V313 K315 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI 6ifz H 3.58 BS02 NUC J 1 S28 N69 A70 N73 R74 N112 E113 W169 K211 P216 L217 S26 N67 A68 N71 R72 N110 E111 W167 K209 P214 L215 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTSLVKNHESFYEMGKANFMIKEI 6ig0 A 3.37 BS02 NUC J 1 A261 T262 N263 G264 A265 K267 H414 Y496 R512 K619 P621 E679 R680 G681 K682 N683 Y686 Y705 Y706 R709 R756 K757 A241 T242 N243 G244 A245 K247 H394 Y476 R492 K599 P601 E659 R660 G661 K662 N663 Y666 Y685 Y686 R689 R736 K737 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ig0 A 3.37 BS04 ATP A 1 D247 I251 Q252 I255 S273 G303 H305 K378 Y573 D577 D227 I231 Q232 I235 S253 G283 H285 K358 Y553 D557 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ig0 A 3.37 BS05 ATP A 2 Y300 D519 V520 D521 D522 L523 G524 F527 M528 G576 D577 K637 Y280 D499 V500 D501 D502 L503 G504 F507 M508 G556 D557 K617 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ig0 A 3.37 BS06 MG A 1 D519 V520 D577 D499 V500 D557 A0A2U2M0F3 KKEKIDLFYGALLHNIGKVIQRATGERKKHALVGADWFDEIADNQVISDQIRYHMANYQSDKLDHLAYITYIADNIASGVDRTYTNQADIFNVFGAQTDKRYFKPTVLNLKSKPNFASATYEPFSKGDYAAIATRIKNELAEFEFNQVQIDSLLNLFEATLSFVPSSTNTKEIADISLADHSRLTAAFALAIYDYLEDKGRHNYKEDLFTKVSAFYEEEAFLLASFDLSGIQDFIYNINIATNGAAKQLKARSLYLDFMSEYIADSLLDKLGLNRANMLYVGGGHAYFVLANTEKTVETLVQFEKDFNQFLLANFQTRLYVAFGWGSFAAKDIMSELNSPESYRQVYQKASRMISKKKISRYDYQTLMLLNRGGKSSERECEICHSVENLVSYHDQKVCDICRGLYQFSKEIAHDHFIITENEGLPIGPNACLKGVAFEKLSQEAFSRVYVKNDYKAGTVKATHVFVGDYQCDEIYNYAALSKNENGLGIKRLAVVRLDVDDLGAAFMAGFSQQGNGQYSTLSRSATFSRSMSLFFKVYINQFASDKKLSIIYAGGDDVFAIGSWQDIIAFTVELRENFIKWTNGKLTLSAGIGLFADKTPISLMAHQTGELEEAAKGNEKDSISLFSSDYTFKFDRFITNVYDDKLEQIRYFFNHQDERGKNFIYKLIELLRNHDRMNMARLAYYLTRLEELTRETDRDKFKTFKNLFYSWYTNKNDKDRKEAELALLLYIYEIRK 6ig0 F 3.37 BS02 NUC J 1 I29 N33 S86 K87 A133 N134 P135 R136 Q137 I28 N32 S85 K86 A132 N133 P134 R135 Q136 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ig0 E 3.37 BS01 NUC N 1 G21 G22 S50 S51 K53 G54 K55 R57 F83 G84 M93 F122 E123 N124 T125 I126 A133 R136 Y181 G183 G184 S185 G186 R188 G20 G21 S49 S50 K52 G53 K54 R56 F73 G74 M83 F112 E113 N114 T115 I116 A123 R126 Y171 G173 G174 S175 G176 R178 A0A2U2M035 TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSSLKGKMRTLLAKVYNESDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTLNELLT 6ig0 B 3.37 BS01 NUC N 1 H14 G16 G18 T19 R31 S34 A35 V37 L38 T132 K133 N134 Q135 P136 H137 L142 Y143 G177 L178 G179 G180 R182 S183 S240 G241 F242 A243 F244 N251 R253 K254 H284 A285 L287 H13 G15 G17 T18 R30 S33 A34 V36 L37 T128 K129 N130 Q131 P132 H133 L138 Y139 G173 L174 G175 G176 R178 S179 S236 G237 F238 A239 F240 N247 R249 K250 H280 A281 L283 A0A2U2M037 TYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTLTDAFPFQFGPFLPKPIGYPKHDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNGELFENEEHAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESDLLNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADLEEAMEDGHYLLTKSSGFAFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPHAVLNYAKPLFFKLEV 6ig0 H 3.37 BS02 NUC J 1 S28 N69 A70 N73 R74 N104 N112 E113 P216 L217 R305 K307 S26 N67 A68 N71 R72 N102 N110 E111 P214 L215 R303 K305 A0A2U2M038 NDYRTFKLSLLTLAPIHIGNGEKYTSREFIYENKKFYFPDMGKFYNKMVEKRLAEKFEAFLIQTRPNARNNRLISFLNDNRIAERSFGGYSISETGLESDKNPNSAGAINEVNKFIRDAFGNPYIPGSSLKGAIRTILMNTTPKWNNENAVNDFGRFPKENKNLIPWGPKKGKEYDDLFNAIRVSDSKPFDNKSLILVQKWDYSAKTNKAKPLPLYRESISPLTKIEFEITTTTDEAGRLIEELGKRAQAFYKDYKAFFLSEFPDDKIQANLQYPIYLGAGSGAWTKTLFKQADGILQRRYSRMKTKMVKKGVLKLTKAPLKTLVKNHESFYEMGKANFMIKEI 6ihx A 1.46 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 P01966 30444368 VLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTSKY 6ihx B 1.46 BS01 HEM B 1 T38 F41 F42 H63 K66 S70 L88 H92 L96 V98 N102 F103 L106 V137 L141 T37 F40 F41 H62 K65 S69 L87 H91 L95 V97 N101 F102 L105 V136 L140 P02070 30444368 MLTAEEKAAVTAFWGKVKVDEVGGEALGRLLVVYPWTQRFFESFGDLSTADAVMNNPKVKAHGKKVLDSFSNGMKHLDDLKGTFAALSELHCDKLHVDPENFKLLGNVLVVVLARNFGKEFTPVLQADFQKVVAGVANALAHRY 6ii1 A 1.34 BS01 HEM A 1 Y42 F43 H45 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y41 F42 H44 H57 K60 A64 L82 L85 H86 L90 V92 N96 F97 L100 L135 P01966 30444368 LSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTS 6ii1 B 1.34 BS01 HEM B 1 T38 F41 F42 H63 K66 V67 S70 F71 L88 H92 L96 V98 N102 F103 L106 L141 T36 F39 F40 H61 K64 V65 S68 F69 L86 H90 L94 V96 N100 F101 L104 L139 P02070 30444368 LTAEEKAAVTAFWGKVKVDEVGGEALGRLLVVYPWTQRFFESFGDLSTADAVMNNPKVKAHGKKVLDSFSNGMKHLDDLKGTFAALSELHCDKLHVDPENFKLLGNVLVVVLARNFGKEFTPVLQADFQKVVAGVANALAHRY 6ii1 D 1.34 BS01 HEM D 1 T38 F41 F42 H63 K66 V67 S70 F71 L88 L91 H92 L96 V98 N102 F103 L106 V137 L141 T37 F40 F41 H62 K65 V66 S69 F70 L87 L90 H91 L95 V97 N101 F102 L105 V136 L140 P02070 30444368 MLTAEEKAAVTAFWGKVKVDEVGGEALGRLLVVYPWTQRFFESFGDLSTADAVMNNPKVKAHGKKVLDSFSNGMKHLDDLKGTFAALSELHCDKLHVDPENFKLLGNVLVVVLARNFGKEFTPVLQADFQKVVAGVANALAHRYH 6iik A 1.97 BS01 IU1 A 1 Q197 Q198 D199 F331 K342 H426 S431 S432 S433 Y436 Y476 Q96 Q97 D98 F211 K215 H276 S281 S282 S283 Y286 Y326 3.4.19.12 P54578 30254335 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRV 6iik B 1.97 BS01 IU1 B 1 Q197 Q198 D199 K342 H426 S431 S433 Y436 Y476 Q96 Q97 D98 K214 H274 S279 S281 Y284 Y324 3.4.19.12 P54578 30254335 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 6iil B 2.20 BS01 A8F B 1 E188 L196 Q197 Q198 D199 F331 K342 H426 S431 S432 S433 Y436 Y476 E87 L95 Q96 Q97 D98 F211 K212 H273 S278 S279 S280 Y283 Y323 3.4.19.12 P54578 30254335 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRV 6il3 A 2.50 BS01 A9R A 1 L616 A642 K644 V675 F691 E692 Y693 C694 G697 D698 L818 D829 F830 L48 A74 K76 V107 F123 E124 Y125 C126 G129 D130 L181 D192 F193 2.7.10.1 P36888 QFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFSNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQL 6iuq A 2.35 BS01 FE2 A 1 H155 D157 H214 H127 D129 H184 KFPGVYKESFTRDYERLHNKISKEVCDQLDDKGYVVIDDCFGHGWASALLEERWLNENDHFKPIFEVDLHDAALRTKVPELDALFHSTELLQALTTHLPQYDLQFSTSDRTLKLQRNAGHGGCFPCHYDNPGAPNKRKVTCLLYLNEGWKEGDGGEVQLFPFLQQPVTVAPKDRVVLFQSDWLHRVLPSHAERYVLTIWLDGAKVNAPEDAQLRLTQSDLADWFGFLERLRRSPVQRLLSRGVYEEEYYESLECQCVELLKSHETHVENVKRNGPLYGFIQRLRDVRAN 6mg1 A 1.75 BS01 NUC C 1 Y274 R278 N281 N282 V285 R289 Y6 R10 N13 N14 V17 R21 P17676 KHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPL 6mg1 B 1.75 BS02 NUC D 1 Y274 R278 N281 N282 V285 R286 R289 K293 Y6 R10 N13 N14 V17 R18 R21 K25 P17676 KHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPL 6mg2 A 1.93 BS01 NUC C 1 K269 Y274 R278 N281 N282 V285 R289 K2 Y7 R11 N14 N15 V18 R22 P17676 MKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFK 6mg2 B 1.93 BS02 NUC D 1 M268 Y274 R278 N281 N282 V285 R289 M1 Y7 R11 N14 N15 V18 R22 P17676 MKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPE 6mj2 A 6.36 BS01 CA A 1 E843 Q846 N869 E1073 E777 Q780 N803 E976 O94759 30467180 IKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSHLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIEDISNKVDAMVDLLDLDGDSYHVNARHLLYPNCPVTRFPVPNEKVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQAGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVKLPLSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFGAHY 6mon A 2.71 BS01 III C 1 V179 G183 F184 T185 E187 L191 V215 Y240 I241 D242 Y258 Y344 L379 N380 V175 G179 F180 T181 E183 L187 V211 Y236 I237 D238 Y254 Y340 L375 N376 2.1.1.-,2.1.1.43 Q9NRG4 30498785 GLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLEFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH 6mon B 2.71 BS01 III D 1 E104 T105 V179 G183 F184 T185 E187 L191 S196 V215 Y240 I241 D242 Y258 Y344 L379 N380 E100 T101 V175 G179 F180 T181 E183 L187 S192 V211 Y236 I237 D238 Y254 Y340 L375 N376 2.1.1.-,2.1.1.43 Q9NRG4 30498785 GLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLEFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH 6mpv A 7.17 BS01 III C 1 N309 L314 N265 L270 Q8IFM8 RHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDENRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKTTAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYE 6mpv A 7.17 BS02 III D 1 E310 N311 S312 I313 K316 E266 N267 S268 I269 K272 Q8IFM8 RHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDENRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKTTAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYE 6mur A 3.10 BS01 NUC H 1 R630 S701 K703 R776 R777 R624 S695 K697 R770 R771 B6YWB8 EIDELTALGGLLANIGKPVQRAGLYSGDHSTQGARFLRDLAENTGRAEYELLSLFSEFHHKGHMKNDELMIRRIKELSPERFGLTMEDVLNALWIVYEADNLASGEPQASRPLYSVFNPGKAYPWAELDFEKELPVPGDVFSIRSQDYRELVKRLWEELSKAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTSAIALAMLRAGCTAEDVRSGRCRKEKRFLLIEGDFSGIQDFIYRVSGKGTLKYLRARSAYLELIGWDVVLEILSRLGLTRANVVFNAGGHFMIIAQNTPDAVKELEEIRAKAVEWLYREFESDLYLAIEWEPVSGREFGREGGKNLFAEARKRLKHKLTVRKLKRFGEIKGLFEHGHTERLAECPVCGRELPEGKLEPSASDPETKVCPTCNRLVSLGGNLPKLLGFGRTAKNDAGVLVEGPFSGFVPYLQGGRPVGEQILVKNTLNPGEIPESAQFVPYFVADYFKKDPKGGVATFEELSMASTGTRRLGVMKGDVDRLGEFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIGDVPSLRDWPEEPDIVVVYAGGDDFFIVGAWDQIFELAFRVRRAFNAYTGGKLTLSVGLGYFDERTPIYRMADVVSERLDTAKDEGRNRVFVVGRSRPLDGKHKLSYEWNHYEELWRTYAPRIYAGNGRLKGKLESKKGLLWKLLEIRELYVRDPNDVRWAYLTAYLLGRHGLSDLFPELVGIDTKAVERKEPQPVYWVDGVLKIVLMAVRR 6mur A 3.10 BS02 ZN A 1 C389 C392 C413 C416 C383 C386 C407 C410 B6YWB8 EIDELTALGGLLANIGKPVQRAGLYSGDHSTQGARFLRDLAENTGRAEYELLSLFSEFHHKGHMKNDELMIRRIKELSPERFGLTMEDVLNALWIVYEADNLASGEPQASRPLYSVFNPGKAYPWAELDFEKELPVPGDVFSIRSQDYRELVKRLWEELSKAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTSAIALAMLRAGCTAEDVRSGRCRKEKRFLLIEGDFSGIQDFIYRVSGKGTLKYLRARSAYLELIGWDVVLEILSRLGLTRANVVFNAGGHFMIIAQNTPDAVKELEEIRAKAVEWLYREFESDLYLAIEWEPVSGREFGREGGKNLFAEARKRLKHKLTVRKLKRFGEIKGLFEHGHTERLAECPVCGRELPEGKLEPSASDPETKVCPTCNRLVSLGGNLPKLLGFGRTAKNDAGVLVEGPFSGFVPYLQGGRPVGEQILVKNTLNPGEIPESAQFVPYFVADYFKKDPKGGVATFEELSMASTGTRRLGVMKGDVDRLGEFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIGDVPSLRDWPEEPDIVVVYAGGDDFFIVGAWDQIFELAFRVRRAFNAYTGGKLTLSVGLGYFDERTPIYRMADVVSERLDTAKDEGRNRVFVVGRSRPLDGKHKLSYEWNHYEELWRTYAPRIYAGNGRLKGKLESKKGLLWKLLEIRELYVRDPNDVRWAYLTAYLLGRHGLSDLFPELVGIDTKAVERKEPQPVYWVDGVLKIVLMAVRR 6mur B 3.10 BS01 NUC H 1 K91 N93 Q137 K68 N70 Q114 B6YWB9 VDASRLFGESPDVVGIKKMLEKGKQWEAIQPYFDNVVREAKNFLEWSPNKRLANAVTVAAYLTSQGLKTNQVRKILDMARTTELKVKRGEGDIKDDLVKMRYLLAYTVGKATGQSKYSLDAFHRILDPMLEVLMGSPKKENFEKFYDFLQAVVAYHKFFGGG 6mur C 3.10 BS01 NUC G 1 G24 S25 S53 S54 K56 G57 R58 R60 S61 I110 V112 G129 A130 S131 N136 S139 I167 E168 V169 G170 I171 R173 S176 A178 R181 Y224 G226 G227 R231 G21 S22 S44 S45 K47 G48 R49 R51 S52 I101 V103 G120 A121 S122 N127 S130 I158 E159 V160 G161 I162 R164 S167 A169 R172 Y215 G217 G218 R222 B6YWC0 RFYGKIVIKGKIKAVTGLHIGSQRGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mur C 3.10 BS02 NUC H 1 N37 N106 R107 A178 N179 P180 R181 N28 N97 R98 A169 N170 P171 R172 B6YWC0 RFYGKIVIKGKIKAVTGLHIGSQRGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mur C 3.10 BS03 ZN C 1 H111 C113 C122 C125 H102 C104 C113 C116 B6YWC0 RFYGKIVIKGKIKAVTGLHIGSQRGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mur D 3.10 BS01 NUC G 1 G24 S53 S54 K56 G57 R58 R60 S61 V112 F128 G129 A130 S131 N136 S139 I167 E168 V169 G170 I171 R173 S176 A178 N179 R181 Y224 G226 G227 S230 R231 G24 S53 S54 K56 G57 R58 R60 S61 V112 F128 G129 A130 S131 N136 S139 I167 E168 V169 G170 I171 R173 S176 A178 N179 R181 Y224 G226 G227 S230 R231 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGSQRDISEIGGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mur D 3.10 BS02 NUC H 1 N37 N106 R107 K133 P180 R181 N37 N106 R107 K133 P180 R181 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGSQRDISEIGGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mur E 3.10 BS01 NUC G 1 R16 T23 G26 A27 G29 N30 S33 Q38 V41 E42 R131 V132 V133 L134 R136 Q139 S141 I143 Y144 G183 I184 G185 G186 K187 W190 K232 G233 G234 W235 S236 F237 K241 R243 H269 E270 V271 Y272 R15 T22 G25 A26 G28 N29 S32 Q37 V40 E41 R130 V131 V132 L133 R135 Q138 S140 I142 Y143 G182 I183 G184 G185 K186 W189 K231 G232 G233 W234 S235 F236 K240 R242 H268 E269 V270 Y271 B6YWC1 PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGGARISSAFPYSGDTYYLPKPLSVEPALEGILTGLDEEERYTTAKRLRKAKYLDLKNFELALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVYFLYSGPREVFDGYIAPAMRFLGDTGIGGKSTWGAGLFEVEFHEMKIDAPGSEYSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPGGMERLELGLSHEVYVYGLTFPLGVELPEG 6mur E 3.10 BS02 NUC H 1 S141 S142 I143 S140 S141 I142 B6YWC1 PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGGARISSAFPYSGDTYYLPKPLSVEPALEGILTGLDEEERYTTAKRLRKAKYLDLKNFELALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVYFLYSGPREVFDGYIAPAMRFLGDTGIGGKSTWGAGLFEVEFHEMKIDAPGSEYSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPGGMERLELGLSHEVYVYGLTFPLGVELPEG 6mur F 3.10 BS01 NUC G 1 G15 T16 G17 S115 S116 K118 G119 A120 R122 Y199 P201 D204 K207 Q234 I236 L335 G336 W337 S339 G340 W341 A343 M344 L366 K368 K369 R377 E378 F379 K381 T382 R384 G15 T16 G17 S109 S110 K112 G113 A114 R116 Y185 P187 D190 K193 Q220 I222 L317 G318 W319 S321 G322 W323 A325 M326 L348 K350 K351 R357 E358 F359 K361 T362 R364 B6YWC2 MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGELNEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKLNGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRDVLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDSKPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNADYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQVRSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGKKGSGFSREFPKTRRLADGMPMGWVVLE 6mur F 3.10 BS02 NUC H 1 R95 S97 R175 R198 K202 P235 I236 P237 I238 R89 S91 R161 R184 K188 P221 I222 P223 I224 B6YWC2 MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGELNEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKLNGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRDVLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDSKPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNADYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQVRSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGKKGSGFSREFPKTRRLADGMPMGWVVLE 6mus B 3.60 BS01 NUC H 1 K91 N93 K47 N49 B6YWB9 KGKQWEAIQPYFDNVVREAKNFLEWSPNKRLANAVTVAAYLTSQGLKTNQVRKILDMARTTELKVKRGEGDIKDDLVKMRYLLAYTVGKATGQSKYSLDAFHRILDPMLEVLMGSPKKENFEKFYDFLQAVVAYHKFFGGG 6mus C 3.60 BS01 NUC G 1 I23 Q26 S53 S54 K56 G57 R58 R60 S61 V112 G129 A130 S131 N136 S139 K166 E168 V169 I171 R173 S176 A178 R181 Y224 G226 G227 R231 I20 Q23 S43 S44 K46 G47 R48 R50 S51 V102 G119 A120 S121 N126 S129 K156 E158 V159 I161 R163 S166 A168 R171 Y214 G216 G217 R221 B6YWC0 RFYGKIVIKGKIKAVTGLHIGSQRIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mus C 3.60 BS02 NUC H 1 N37 R107 I167 A178 N179 P180 R181 N27 R97 I157 A168 N169 P170 R171 B6YWC0 RFYGKIVIKGKIKAVTGLHIGSQRIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mus D 3.60 BS01 NUC G 1 I23 S25 Q26 S53 S54 K56 G57 R58 R60 I105 I110 V112 G129 A130 S131 N136 S139 I167 E168 V169 I171 R173 A178 R181 Y224 G226 G227 R231 I23 S25 Q26 S53 S54 K56 G57 R58 R60 I105 I110 V112 G129 A130 S131 N136 S139 I167 E168 V169 I171 R173 A178 R181 Y224 G226 G227 R231 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGSQRDISEIGGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mus D 3.60 BS02 NUC H 1 N37 N106 R107 K133 Q177 A178 P180 R181 N37 N106 R107 K133 Q177 A178 P180 R181 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGSQRDISEIGGIANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mus E 3.60 BS02 NUC H 1 S141 S142 S133 S134 B6YWC1 PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGGARISSAFPYSGDTYYLPKPLSVEPALEGILRYTTAKRLRKAKYLDLKNFELALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVYFLYSGPREVFDGYIAPAMRFLGDTGIGGKSTWGAGLFEVEFHEMKIDAPGSEYSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPGGMERLELGLSHEVYVYGLTFPLGVELPEG 6mus J 3.60 BS01 NUC H 1 N93 R96 N38 R41 B6YWB9 WEAIQPYFDNVVREAKNFLEWSPNKRLANAVTVAAKTNQVRKILDMARTTELKIKDDLVKMRYLLAYTVGKATGQSKYSLDAFHRILDPMLEVLMGSPKKENFEKFYDFLQAVVAYHKFFG 6mus K 3.60 BS01 NUC G 1 I23 S53 S54 K56 G57 R58 S61 I105 F128 S131 N136 S139 I167 E168 V169 G170 I171 R173 S176 A178 R181 Y224 G226 G227 S228 S230 R231 I23 S41 S42 K44 G45 R46 S49 I93 F116 S119 N124 S127 I155 E156 V157 G158 I159 R161 S164 A166 R169 Y212 G214 G215 S216 S218 R219 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGNPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mus K 3.60 BS02 NUC H 1 N37 I105 R107 G132 K133 E134 N179 P180 R181 T182 N25 I93 R95 G120 K121 E122 N167 P168 R169 T170 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGNPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mus F 3.60 BS01 NUC G 1 I14 G15 T16 G17 S115 S116 K118 G119 A120 R122 Y199 P201 K202 D204 Q234 R334 L335 G336 W337 S339 W341 A343 M344 L366 K368 K369 R377 E378 F379 K381 T382 R384 I14 G15 T16 G17 S109 S110 K112 G113 A114 R116 Y185 P187 K188 D190 Q220 R316 L317 G318 W319 S321 W323 A325 M326 L348 K350 K351 R357 E358 F359 K361 T362 R364 B6YWC2 MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGELNEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKLNGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRDVLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDSKPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNADYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQVRSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGKKGSGFSREFPKTRRLADGMPMGWVVLE 6mus F 3.60 BS02 NUC H 1 R95 S97 M98 R198 I236 I238 R89 S91 M92 R184 I222 I224 B6YWC2 MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGELNEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKLNGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRDVLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDSKPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNADYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQVRSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGKKGSGFSREFPKTRRLADGMPMGWVVLE 6mut A 3.10 BS01 NUC H 1 R385 R630 K703 R385 R630 K690 B6YWB8 MEIDELTALGGLLHDIGKPVQRAGLYSGDHSTQGARFLRDLAENTGRAEYELLSLFSEFHHKGHMKNDELMIRRIKELSPERFGLTMEDVLNALWIVYEADNLASGEREEGQPQASRPLYSVFNPGKAYPWAELDFEKELPVPGDVFSIRSQDYRELVKRLWEELSKAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTSAIALAMLRAGCTAEDVRSGRCRKEKRFLLIEGDFSGIQDFIYRVSGKGTLKYLRARSAYLELIGWDVVLEILSRLGLTRANVVFNAGGHFMIIAQNTPDAVKELEEIRAKAVEWLYREFESDLYLAIEWEPVSGREFGREGGKNLFAEARKRLKHKLTVRKLKRFGEIKGLFEHGHTERLAECPVCGRELPEGKLEPSASDPETKVCPTCNRLVSLGGNLPKLLGFGRTAKNDAGVLVEGPFSGFVPYLQGGRPVGEQILVKNTLNPGEIPESAQFVPYFVADYFKKDPKGGVATFEELSMASTGTRRLGVMKGDVDRLGEFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIGDVPSLRDWPEEPDIVVVYAGGDDFFIVGAWDQIFELAFRVRRAFNAYTGGKLTLSVGLGYFDERTPIYRMADVVSERLDTAKDEGRNRVFVVPLDGKHKLSYEWNHYEELWRTYAPRIYLESKKGLLWKLLEIRELYVRVRWAYLTAYLLGRHGLSDLFPELVQPVYWVDGVLKIVLMAVR 6mut C 3.10 BS01 NUC G 1 G24 S25 S53 S54 K56 G57 R58 R60 S61 G129 S131 P138 S139 I167 E168 V169 G170 I171 R173 A178 R181 Y224 G226 G227 S230 R231 G22 S23 S42 S43 K45 G46 R47 R49 S50 G118 S120 P127 S128 I156 E157 V158 G159 I160 R162 A167 R170 Y213 G215 G216 S219 R220 B6YWC0 RRFYGKIVIKGKIKAVTGLHIGSQANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mut C 3.10 BS02 NUC H 1 N37 I105 N106 K133 A178 P180 R181 N26 I94 N95 K122 A167 P169 R170 B6YWC0 RRFYGKIVIKGKIKAVTGLHIGSQANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mut D 3.10 BS01 NUC G 1 I23 G24 Q26 S53 S54 K56 G57 R58 R60 V112 G129 A130 S131 N136 S139 E168 R181 N183 Y224 G226 G227 S228 S230 R231 I23 G24 Q26 S44 S45 K47 G48 R49 R51 V103 G120 A121 S122 N127 S130 E159 R161 N163 Y204 G206 G207 S208 S210 R211 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGSQANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mut D 3.10 BS02 NUC H 1 A36 N37 R107 K133 R181 A27 N28 R98 K124 R161 B6YWC0 MDRRFYGKIVIKGKIKAVTGLHIGSQANPVIKDPHTGLPYIPGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL 6mut E 3.10 BS01 NUC G 1 R16 T23 G26 A27 N30 S33 Q38 V41 E42 P130 R131 V132 V133 L134 R136 Q139 S141 I143 Y144 W146 I184 G185 G186 K187 T189 K232 G233 G234 W235 S236 F237 K241 R243 H269 E270 Y272 R15 T22 G25 A26 N29 S32 Q37 V40 E41 P129 R130 V131 V132 L133 R135 Q138 S140 I142 Y143 W145 I183 G184 G185 K186 T188 K231 G232 G233 W234 S235 F236 K240 R242 H268 E269 Y271 B6YWC1 PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGGARISSAFPYSGDTYYLPKPLSVEPALEGILTGLDEEERYTTAKRLRKAKYLDLKNFELALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVYFLYSGPREVFDGYIAPAMRFLGDTGIGGKSTWGAGLFEVEFHEMKIDAPGSEYSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPGGMERLELGLSHEVYVYGLTFPLGVELPEG 6mut E 3.10 BS02 NUC H 1 S141 S142 I143 Y144 W235 R239 L265 G266 S140 S141 I142 Y143 W234 R238 L264 G265 B6YWC1 PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGGARISSAFPYSGDTYYLPKPLSVEPALEGILTGLDEEERYTTAKRLRKAKYLDLKNFELALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVYFLYSGPREVFDGYIAPAMRFLGDTGIGGKSTWGAGLFEVEFHEMKIDAPGSEYSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPGGMERLELGLSHEVYVYGLTFPLGVELPEG 6mut F 3.10 BS01 NUC G 1 S115 S116 G119 A120 R122 Y199 P201 K207 S109 S110 G113 A114 R116 Y185 P187 K193 B6YWC2 MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGELNEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKLNGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRDVLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDSKPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNADYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQVRSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGKKGSGFSREFPKTRRLADGMPMGWVVLE 6mx8 A 1.96 BS01 6GY A 1 L1122 A1148 L1196 E1197 M1199 A1200 G1202 E1210 R1253 L1256 D1270 L29 A45 L93 E94 M96 A97 G99 E107 R148 L151 D165 2.7.10.1 Q9UM73 27144831 PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGEVYEGQVSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMACAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIE 6n2j A 1.80 BS02 K9M A 1 G10 C12 K16 P34 A59 G60 E62 E63 Y64 R68 D69 M72 H95 Y96 Q99 I100 R102 V103 G9 C11 K15 P33 A58 G59 E61 E62 Y63 R67 D68 M71 H94 Y95 Q98 I99 R101 V102 P01116 TEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 6n2k A 1.72 BS02 K9J A 1 G10 A11 C12 K16 P34 A59 G60 E62 E63 Y64 R68 D69 M72 D92 H95 Y96 Q99 I100 V103 G10 A11 C12 K16 P34 A59 G60 E62 E63 Y64 R68 D69 M72 D92 H95 Y96 Q99 I100 V103 P01116 MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 6n7f A 1.90 BS01 FAD A 1 I10 G11 G13 S14 A15 A33 E34 G35 K36 G40 T41 C42 G46 C47 K50 Y114 A115 A138 T139 G140 Y177 I178 R263 F270 G302 D303 A309 L310 T311 P312 I11 G12 G14 S15 A16 A34 E35 G36 K37 G41 T42 C43 G47 C48 K51 Y115 A116 A139 T140 G141 Y178 I179 R264 F271 G303 D304 A310 L311 T312 P313 1.8.1.7 Q9A0E2 AMVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 6n7f A 1.90 BS02 RBF A 1 G35 K36 Y114 H142 N266 E268 G269 G36 K37 Y115 H143 N267 E269 G270 1.8.1.7 Q9A0E2 AMVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 6n7f A 1.90 BS03 BCT A 1 N292 T330 N293 T331 1.8.1.7 Q9A0E2 AMVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 6n7f B 1.90 BS01 FAD A 1 H439 P440 H439 P440 1.8.1.7 Q9A0E2 MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGFFALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKLDYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 6n7l A 2.10 BS01 NAD A 1 C43 H44 T45 H48 C152 T156 S175 G176 I177 G178 G179 L180 D199 V200 K204 T241 A242 V243 A247 N264 G265 L266 S288 I289 V290 R335 C43 H44 T45 H48 C152 T156 S175 G176 I177 G178 G179 L180 D199 V200 K204 T241 A242 V243 A247 N264 G265 L266 S288 I289 V290 R335 A0A077EGR8 MIPKTMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGHEGVGIVVACGPDAMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDIAG 6n7l A 2.10 BS02 ZN A 1 C43 H66 C152 C43 H66 C152 A0A077EGR8 MIPKTMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGHEGVGIVVACGPDAMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDIAG 6n7l A 2.10 BS03 ZN A 2 C96 C99 C102 C110 C96 C99 C102 C110 A0A077EGR8 MIPKTMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGHEGVGIVVACGPDAMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDIAG 6n7l D 2.10 BS01 NAD D 1 C43 H44 T45 H48 C152 T156 S175 G176 I177 G178 G179 L180 D199 V200 K204 T241 A242 V243 S244 I246 A247 N264 G265 L266 S288 I289 V290 M327 R335 C43 H44 T45 H48 C152 T156 S175 G176 I177 G178 G179 L180 D199 V200 K204 T241 A242 V243 S244 I246 A247 N264 G265 L266 S288 I289 V290 M327 R335 A0A077EGR8 MIPKTMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGHEGVGIVVACGPDAMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDIAGS 6n8g A 2.00 BS01 KFD A 1 M192 G195 V200 A211 K213 V246 Y262 V263 Y264 M265 P266 G268 A315 N316 L318 S328 D329 M29 G32 V37 A48 K50 V79 Y95 V96 Y97 M98 P99 G101 A148 N149 L151 S161 D162 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 6n8g B 2.00 BS01 KFD B 1 I185 M192 G195 G196 V200 A211 K213 V246 Y262 V263 Y264 M265 P266 G268 S269 A315 N316 L318 S328 D329 I22 M29 G32 G33 V37 A48 K50 V78 Y94 V95 Y96 M97 P98 G100 S101 A147 N148 L150 S160 D161 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLATTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 6n8g D 2.00 BS01 KFD D 1 M192 G193 E194 G195 G196 V200 A211 K213 V246 Y262 V263 Y264 M265 P266 G268 A315 N316 L318 S328 D329 M29 G30 E31 G32 G33 V37 A48 K50 V72 Y88 V89 Y90 M91 P92 G94 A141 N142 L144 S154 D155 2.7.11.1 Q9NWZ3 RFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTA 6q4l A 2.30 BS02 3K0 A 1 H69 E72 R129 N146 R147 H204 T205 L211 A251 Y255 D260 E277 H69 E72 R129 N146 R147 H204 T205 L211 A251 Y255 D260 E277 3.4.17.18 P29068 DFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDNYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSC