5wa1 A 1.87 BS01 III B 1 D143 L146 K147 K151 F199 K202 M208 K209 I212 L216 L337 D143 L146 K147 K151 F199 K202 M208 K209 I212 L216 L337 Q8WUM4 30181294 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKM 5wfv A 1.91 BS01 III P 1 Y334 S363 R380 N382 N387 R415 R483 S508 G509 Y525 Q530 S555 Y572 F577 S602 Y9 S38 R55 N57 N62 R90 R158 S183 G184 Y200 Q205 S230 Y247 F252 S277 Q14145 RLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 5wg1 A 2.02 BS01 III P 1 Y334 S363 R380 N382 R415 S508 G509 Y525 Q530 S555 A556 Y572 F577 S602 Y5 S34 R51 N53 R86 S179 G180 Y196 Q201 S226 A227 Y243 F248 S273 Q14145 TAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 5whl A 2.50 BS01 HPP A 1 R415 F478 R483 S508 S555 R86 F149 R154 S179 S226 Q14145 TAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT 5xgk A 2.80 BS01 TYF A 1 H226 V228 H308 Q379 F381 E394 F419 G420 N423 H177 V179 H246 Q317 F319 E332 F350 G351 N354 1.13.11.27 P93836 FSKFVRKNPKSDKFKVKRFHHIEFWCGDATNVARRFSWGLGMRFSAKSDLSTGNMVHASYLLTSGDLRFLFTAPYSPSPTTTASIPSFDHGSCRSFFSSHGLGVRAVAIEVEDAESAFSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSFLPGFERVEDPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTSGLNSAVLASNDEMVLLPINEPVKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGFDFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQRVGCMMYQSGGCGGFGKGNFSELFKSIEEYEKT 5y24 A 1.92 BS01 III C 1 Y159 L162 F167 V198 N202 L205 N206 R228 F232 N239 L242 I269 Q272 A273 F276 M296 Q299 E300 N329 D360 F362 L363 Y117 L120 F125 V156 N160 L163 N164 R186 F190 N197 L200 I227 Q230 A231 F234 M254 Q257 E258 N287 D318 F320 L321 O64094 DKTFNEFSSIVNIVKSQYPDREYELMKDYCLNLDVKTKAARSALEYADANMFFEIEDVLIDSMISCNMKSKEYGKVYKIHRELSNSVITEFEAVKRLGKLNIKTPEMNSFSRLLLLYHYLSTGNFSPMAQLIKQIDLSEISENMYIRNTYQTRVHVLMSNIKLNENSLEECREYSKKALESTNILRFQVFSYLTIGNSLLFSNYELAQENFLKGLSISVQNENYNMIFQQALCFLNNVWRKENKWINFESDSIMDLQEQAHCFINFNENSKAKEVLDKLDLLVHNDNELAMHYYLKGRLEQNKACFYSSIEYFKKSNDKFLIRLPLLELQKMGENQKLLELLLLLEHH 5y24 B 1.92 BS01 III D 1 Y159 L162 F167 V198 L199 N202 N206 R228 F232 L235 N239 L242 Q272 A273 F276 M296 Q299 E300 N329 D360 L363 Y119 L122 F127 V158 L159 N162 N166 R188 F192 L195 N199 L202 Q232 A233 F236 M256 Q259 E260 N289 D320 L323 O64094 DGKTFNEFSSIVNIVKSQYPDREYELMKDYCLNLDVKTKAARSALEYADANMFFEIEDVLIDSMISCSNMKSKEYGKVYKIHRELSNSVITEFEAVKRLGKLNIKTPEMNSFSRLLLLYHYLSTGNFSPMAQLIKQIDLSEISENMYIRNTYQTRVHVLMSNIKLNENSLEECREYSKKALESTNILRFQVFSYLTIGNSLLFSNYELAQENFLKGLSISVQNENYNMIFQQALCFLNNVWRKENKWINFESDSIMDLQEQAHCFINFNENSKAKEVLDKLDLLVHNDNELAMHYYLKGRLEQNKACFYSSIEYFKKSNDKFLIRLPLLELQKMGENQKLLELLLLLEHH 5ycg A 2.40 BS01 HEM A 1 T39 K42 F43 H64 T67 V68 L89 S92 H93 H97 I99 Y103 I107 F138 T40 K43 F44 H65 T68 V69 L90 S93 H94 H98 I100 Y104 I108 F139 MGLSDGEWQLVLNVWGKVEADVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEDEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLQSKHPGDFGADAQGAMNKALELFRNDIAAKYKELGFQG 5yci B 1.97 BS01 HEM B 1 T39 K42 F43 H64 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 T43 K46 F47 H68 T71 V72 A75 L93 S96 H97 H101 I103 Y107 L108 GSHMGLSDGEWQLVLNIWGKVEADVAGHGQDVLIRLFKGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGFQG 5ycj A 1.58 BS01 HEM A 1 T39 F43 H64 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 I107 F138 T40 F44 H65 T68 V69 A72 L90 S93 H94 H98 I100 Y104 L105 I108 F139 MGLSDGEWQLVLNIWGKVEADVAGHGQDVLIRLFKGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGFQG 5ydd B 1.50 BS01 8TU B 1 H164 R223 A226 I230 H39 R98 A101 I105 P9WME7 MRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSAVRDVLH 5ypp A 1.90 BS01 VAL A 1 V17 N19 H20 G22 V23 M24 C43 V9 N11 H12 G14 V15 M16 C35 2.2.1.6 P0ADF8 DNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5ypp A 1.90 BS02 VAL A 2 N37 V38 N29 V30 2.2.1.6 P0ADF8 DNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5ypp C 1.90 BS01 VAL C 1 N19 H20 G22 V23 M24 C43 N11 H12 G14 V15 M16 C35 2.2.1.6 P0ADF8 DNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5ypp E 1.90 BS01 VAL E 1 N19 H20 P21 G22 V23 M24 C43 N12 H13 P14 G15 V16 M17 C36 2.2.1.6 P0ADF8 HDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5ypw C 2.30 BS01 VAL C 1 V17 N19 H20 P21 G22 V23 M24 C43 V9 N11 H12 P13 G14 V15 M16 C35 2.2.1.6 P0ADG0 DNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5ypw F 2.30 BS01 VAL E 1 N37 V38 I41 N30 V31 I34 2.2.1.6 P0ADG0 HDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5ypy A 1.97 BS01 VAL A 1 V17 N19 H20 G22 V23 M24 C43 S52 V10 N12 H13 G15 V16 M17 C36 S45 2.2.1.6 P0ADF8 HDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5yrt A 1.70 BS02 B12 B 1 T172 V173 A174 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A375 T172 V173 A174 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A375 4.2.1.28 Q59470 29797764 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5yrt B 1.70 BS01 B12 B 1 D112 V113 A114 K135 T137 L148 N150 L153 P155 Q156 A157 P158 R193 Y196 S200 D70 V71 A72 K93 T95 L106 N108 L111 P113 Q114 A115 P116 R151 Y154 S158 4.2.1.28 Q59471 29797764 GPGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL 5yrv J 1.55 BS02 B12 K 1 T172 V173 A174 S202 L203 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A375 T172 V173 A174 S202 L203 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A375 4.2.1.28 Q59470 29797764 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5ysc A 1.67 BS01 CNC A 1 P33 H34 E53 Y54 N69 H70 W89 A91 G92 L166 Y200 A249 D250 N253 R254 P12 H13 E32 Y33 N48 H49 W68 A70 G71 L145 Y179 A228 D229 N232 R233 A5F5P5 PFPAERIISLAPHATEIAYAAGLGDKLVAVSEYSDYPPQALELERVANHQTINIEKILTLKPDLIIAWPAGNPPRELAKLRQLGFTIYDSQTKTLDEIADNIEALSHYSANPEVGQKAAHDFRQRLQDLRTQYASNQPIRYFYQLSEKPIITLAQGHWPSEVFSLCGGVNIFADSEVPYPQVSIEQVLVKQPQVIFTSEHAIANGHMWRAWQAELSAVQNDQVWALNADWLNRPTPRTLDAVEQVCTYLKIAQKQ 5ysh A 1.90 BS03 B12 B 1 A172 V173 A174 S202 E205 T222 S224 D234 Q267 M268 S301 Q336 M373 F374 A375 A172 V173 A174 S202 E205 T222 S224 D234 Q267 M268 S301 Q336 M373 F374 A375 4.2.1.28 Q59470 29797764 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5ysh D 1.90 BS03 B12 E 1 A172 V173 S202 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A375 A172 V173 S202 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A375 4.2.1.28 Q59470 29797764 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDP 5ysh G 1.90 BS03 B12 H 1 A172 S202 E205 T222 S224 D234 Q267 M268 S301 Q336 M373 F374 A375 A172 S202 E205 T222 S224 D234 Q267 M268 S301 Q336 M373 F374 A375 4.2.1.28 Q59470 29797764 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDP 5ysh H 1.90 BS01 B12 H 1 D112 V113 K135 T137 L148 N150 L153 P155 Q156 A157 R193 Q197 S200 D69 V70 K92 T94 L105 N107 L110 P112 Q113 A114 R150 Q154 S157 4.2.1.28 Q59471 29797764 PGGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVA 5ysh J 1.90 BS03 B12 K 1 A172 S202 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 A172 S202 E205 T222 D234 Q267 M268 S301 Q336 M373 F374 4.2.1.28 Q59470 29797764 MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETAVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN 5ysh K 1.90 BS01 B12 K 1 D112 K135 T137 L148 N150 L153 P155 Q156 A157 P158 R193 Y196 S200 D61 K84 T86 L93 N95 L98 P100 Q101 A102 P103 R138 Y141 S145 4.2.1.28 Q59471 29797764 TEVGEARQQDEVIIAVGPAFGLAQTVNIVGIPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRV 5ysn A 2.00 BS01 B12 B 1 N193 P194 V195 A226 H227 F245 Q246 S247 E257 F258 S295 F329 I330 M401 L402 N403 N193 P194 V195 A226 H227 F245 Q246 S247 E257 F258 S295 F329 I330 M401 L402 N403 4.3.1.7 P0AEJ6 29797764 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysn C 2.00 BS01 B12 D 1 P194 A226 F245 Q246 S247 E257 F258 S295 F329 I330 M401 L402 P194 A226 F245 Q246 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 P0AEJ6 29797764 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysr A 2.05 BS01 B12 B 1 N193 P194 V195 T196 L225 A226 H227 F245 Q246 S247 E257 F258 S295 F329 I330 M401 L402 N193 P194 V195 T196 L225 A226 H227 F245 Q246 S247 E257 F258 S295 F329 I330 M401 L402 4.3.1.7 P0AEJ6 29797764 MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF 5ysr D 2.05 BS01 B12 D 1 L169 R206 V207 K208 G227 E228 R229 Y241 E253 R256 C258 S260 N261 L126 R163 V164 K165 G184 E185 R186 Y198 E210 R213 C215 S217 N218 4.3.1.7 P19636 29797764 ALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMT 5yum A 2.43 BS02 CO A 1 H20 D76 H13 D69 2.2.1.6 P0ADF8 HDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ 5z20 A 2.20 BS01 NAI A 1 Y100 V105 T152 G153 Q154 I155 Y173 D174 P175 H204 C205 P206 T211 T232 G233 R234 D258 H295 A297 F298 Y101 V106 T153 G154 Q155 I156 Y174 D175 P176 H205 C206 P207 T212 T233 G234 R235 D259 H296 A298 F299 1.1.1.28 Q9I530 30149697 HMRILFFSSQAYDSESFQASNHRHGFELHFQQAHLQADTAVLAQGFEVVCAFVNDDLSRPVLERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRLHRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLTREALAAIADTTLDNIAAWQDGTPRNRVRA 5z20 A 2.20 BS02 OXM A 1 V52 S76 A77 G78 Y100 R234 H295 F298 V53 S77 A78 G79 Y101 R235 H296 F299 1.1.1.28 Q9I530 30149697 HMRILFFSSQAYDSESFQASNHRHGFELHFQQAHLQADTAVLAQGFEVVCAFVNDDLSRPVLERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRLHRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLTREALAAIADTTLDNIAAWQDGTPRNRVRA 5z21 A 2.30 BS01 NAI A 1 Y102 I107 T154 G155 K156 I157 Y175 D176 L177 F178 C208 P209 T214 T235 G236 R237 D261 H298 A300 Y301 Y99 I104 T151 G152 K153 I154 Y172 D173 L174 F175 C205 P206 T211 T232 G233 R234 D258 H295 A297 Y298 1.1.1.28 Q8RG11 30149697 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKGYDVVCGFANDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNERFKVVRVPAYSPHAIAEYTVGLILAVNRKINKAYVRTREGNFSINGLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYDLFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEVPQ 5z21 A 2.30 BS02 OXM A 1 C79 A80 G81 Y102 R237 H298 Y301 C76 A77 G78 Y99 R234 H295 Y298 1.1.1.28 Q8RG11 30149697 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKGYDVVCGFANDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNERFKVVRVPAYSPHAIAEYTVGLILAVNRKINKAYVRTREGNFSINGLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYDLFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEVPQ 5z21 B 2.30 BS01 NAI B 1 Y102 I107 T154 G155 K156 I157 Y175 D176 L177 N207 P209 T214 T235 G236 R237 D261 H298 A300 Y301 Y100 I105 T152 G153 K154 I155 Y173 D174 L175 N205 P207 T212 T233 G234 R235 D259 H296 A298 Y299 1.1.1.28 Q8RG11 30149697 KTKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKGYDVVCGFANDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNERFKVVRVPAYSPHAIAEYTVGLILAVNRKINKAYVRTREGNFSINGLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYDLFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEVPQ 5z21 D 2.30 BS01 NAI D 1 Y102 I107 T154 G155 K156 I157 Y175 D176 L177 P209 D213 T214 T235 G236 R237 D261 H298 A300 Y301 Y100 I105 T152 G153 K154 I155 Y173 D174 L175 P207 D211 T212 T233 G234 R235 D259 H296 A298 Y299 1.1.1.28 Q8RG11 30149697 KTKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKGYDVVCGFANDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNERFKVVRVPAYSPHAIAEYTVGLILAVNRKINKAYVRTREGNFSINGLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYDLFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEVPQ 5z6f A 1.80 BS01 FOL A 1 A6 A7 M20 D27 L28 A29 F31 K32 I50 R57 I94 T113 A7 A8 M21 D28 L29 A30 F32 K33 I51 R58 I95 T114 1.5.1.3 P0ABQ4 30198899 HMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5z6f A 1.80 BS02 NAP A 1 A6 A7 I14 G15 N18 A19 M20 G43 R44 H45 T46 L62 S63 S64 K76 I94 G95 G96 G97 R98 V99 Y100 Q102 A7 A8 I15 G16 N19 A20 M21 G44 R45 H46 T47 L63 S64 S65 K77 I95 G96 G97 G98 R99 V100 Y101 Q103 1.5.1.3 P0ABQ4 30198899 HMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5z6j A 1.80 BS02 NAP A 1 A6 A7 I14 G15 N18 A19 M20 W22 G43 R44 H45 T46 L62 S63 S64 Q65 K76 I94 G95 G96 G97 R98 V99 Y100 Q102 T123 A7 A8 I15 G16 N19 A20 M21 W23 G44 R45 H46 T47 L63 S64 S65 Q66 K77 I95 G96 G97 G98 R99 V100 Y101 Q103 T124 1.5.1.3 P0ABQ4 30198899 HMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5z6k A 1.80 BS01 FOL A 1 I5 A6 A7 M20 D27 L28 A29 F31 K32 I50 L54 R57 I94 T113 I6 A7 A8 M21 D28 L29 A30 F32 K33 I51 L55 R58 I95 T114 1.5.1.3 P0ABQ4 30198899 HMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5z6l A 1.90 BS01 FOL A 1 I5 A6 A7 M20 D27 L28 F31 K32 P55 R57 I94 I6 A7 A8 M21 D28 L29 F32 K33 P56 R58 I95 1.5.1.3 P0ABQ4 30198899 HMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5z6m A 2.20 BS01 FOL A 1 I5 A6 A7 M20 D27 L28 W30 F31 L54 I94 Y100 T113 I6 A7 A8 M21 D28 L29 W31 F32 L55 I95 Y101 T114 1.5.1.3 P0ABQ4 30198899 HMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5zd7 A 1.60 BS01 CU A 1 H398 C457 H462 Q467 H400 C459 H464 Q469 1.3.3.5 Q12737 30156345 KRVAQISPQYPMFTVPLPIPPVKQPRLTVTNPVNGQEIWYYEVEIKPFTHQVYPDLGSADLVGYDGMSPGPTFQVPRGVETVVRFINNAEAPNSVHLHGSFSRAAFDGWAEDITEPGSFKDYYYPNRQSARTLWYHDHAMHITAENAYRGQAGLYMLTDPAEDALNLPSGYGEFDIPMILTSKQYTANGNLVTTNGELNSFWGDVIHVNGQPWPFKNVEPRKYRFRFLDAAVSRSFGLYFADTDAIDTRLPFKVIASDSGLLEHPADTSLLYISMAERYEVVFDFSDYAGKTIELRNLGGSIGGIGTDTDYDNTDKVMRFVVADDTTQPDTSVVPANLRDVPFPSPTTNTPRQFRFGRTGPTWTINGVAFADVQNRLLANVPVGTVERWELINAGNGWTHPIHIHLVDFKVISRTSGNNARTVMPYESGLKDVVWLGRRETVVVEAHYAPFPGVYMFHCHNLIHEDHDQMAAFNATVLPDYGYNATVFVDPMEELWQARPYELGEFQAQSGQFSVQAVTERIQTMAEYRPYAAADE 5zi5 A 2.60 BS01 ZN A 1 H310 H314 E333 H298 H302 E321 3.4.11.2 Q5ZVE3 30172821 SKVKKLSDYKSLDYFVIHVDLQIDLSKKPVESKARLTVVPNLNVDSHSNDLVLDGENMTLVSLQMNDNLLKENEYELTKDSLIIKNIPQNTPFTIEMTSLLGENTDLFGLYETEGVALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLLSNGVLIEKKELPLGLHSVTWLDDVPKPSYLFALVAGNLQRSVTYYQTKSGRELPIEFYVPPSATSKCDFAKEVLKEAMAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKTDLGILRVLEVVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFRAAMFREELFGTDLIRLLDGKNLDERAPRQSAYTAVRSLYTAAAYEKSADIFRMMMLFIGKEPFIEAVAKFFKDNDGGAVTLEDFIESISNSSGKDLRSFLSWFTESGIPELIVTDELNPDTKQYFLKIKTVNGRNRPIPILMGLLDSSGAEIVADKLLIVDQEEIEFQFENIQTRPIPSLLRSFSAPVHMKYEYSYQDLLLLMQFDTNLYNRCEAAKQLISALINDFCIGKKIELSPQFFAVYKALLSDNSLNEWMLAELITLPSLEELIENQDKPDFEKLNEGRQLIQNALANELKTDFYNLLFRIQISGDDDKQKLKGFDLKQAGLRRLKSVCFSYLLNVDFEKTKEKLILQFEDALGKNMTETALALSMLCEINCEEADVALEDYYHYWKNDPGAVNNWFSIQALAHSPDVIERVKKLMRHGDFDLSNPNKVYALLGSFIKNPFGFHSVTGEGYQLVADAIFDLDKINPTLAANLTEKFTYWDKYDVNRQAMMISTLKIIYSNATSSDVRTMAKKGLDKV 5zi7 A 1.86 BS01 GLU A 1 K132 E134 S273 A275 S276 E277 H310 E311 H314 K332 E333 R375 Y378 Y383 K120 E122 S261 A263 S264 E265 H298 E299 H302 K320 E321 R363 Y366 Y371 3.4.11.2 Q5ZVE3 30172821 SKVKKLSDYKSLDYFVIHVDLQIDLSKKPVESKARLTVVPNLNVDSHSNDLVLDGENMTLVSLQMNDNLLKENEYELTKDSLIIKNIPQNTPFTIEMTSLLGENTDLFGLYETEGVALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLLSNGVLIEKKELPLGLHSVTWLDDVPKPSYLFALVAGNLQRSVTYYQTKSGRELPIEFYVPPSATSKCDFAKEVLKEAMAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKTDLGILRVLEVVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFRAAMFREELFGTDLIRLLDGKNLDERAPRQSAYTAVRSLYTAAAYEKSADIFRMMMLFIGKEPFIEAVAKFFKDNDGGAVTLEDFIESISNSSGKDLRSFLSWFTESGIPELIVTDELNPDTKQYFLKIKTVNGRNRPIPILMGLLDSSGAEIVADKLLIVDQEEIEFQFENIQTRPIPSLLRSFSAPVHMKYEYSYQDLLLLMQFDTNLYNRCEAAKQLISALINDFCIGKKIELSPQFFAVYKALLSDNSLNEWMLAELITLPSLEELIENQDKPDFEKLNEGRQLIQNALANELKTDFYNLLFRIQISGDDDKQKLKGFDLKQAGLRRLKSVCFSYLLNVDFEKTKEKLILQFEDALGKNMTETALALSMLCEINCEEADVALEDYYHYWKNDPGAVNNWFSIQALAHSPDVIERVKKLMRHGDFDLSNPNKVYALLGSFIKNPFGFHSVTGEGYQLVADAIFDLDKINPTLAANLTEKFTYWDKYDVNRQAMMISTLKIIYSNATSSDVRTMAKKGLDKV 5zjn A 2.66 BS01 LRY A 1 Q24 R53 K76 I86 T155 Y159 E186 G187 R188 V208 G209 S210 R214 Q17 R46 K69 I79 T148 Y152 E175 G176 R177 V197 G198 S199 R203 5.1.3.9 A0A2K2UT85 29969107 IEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVSNVAAVSAAVTIPIIGIVKRDLPDSPVRITPFVSDVDGLANAGATVIAFDATNRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGE 5zjn B 2.66 BS01 LRY B 1 Q24 R53 K76 Y159 E186 R188 G209 S210 R214 Q19 R48 K71 Y154 E177 R179 G200 S201 R205 5.1.3.9 A0A2K2UT85 29969107 LNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVSNVAAVSAAVTIPIIGIVKRDLPDSPVRITPFVSDVDGLANAGATVIAFDATNRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQAAGER 5zyt A 2.70 BS01 NUC E 1 S132 T134 Q138 Q145 L148 L149 R151 W152 V172 F173 G176 H180 G235 L236 K253 T254 S255 E256 K259 S264 F266 Y275 S26 T28 Q32 Q39 L42 L43 R45 W46 V66 F67 G70 H74 G120 L121 K138 T139 S140 E141 K144 S149 F151 Y160 3.1.-.- Q9BQP7 VPQNWFPIFNPERPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKKNQ 5zyt B 2.70 BS01 NUC F 1 S132 T134 Q138 Q145 L148 L149 W152 V172 F173 G176 H180 I234 G235 L236 D238 K253 T254 S255 E256 P258 K259 P260 S264 F266 Y275 S27 T29 Q33 Q40 L43 L44 W47 V67 F68 G71 H75 I120 G121 L122 D124 K139 T140 S141 E142 P144 K145 P146 S150 F152 Y161 3.1.-.- Q9BQP7 VPQNWFPIFNPERSPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK 5zyt C 2.70 BS01 NUC G 1 S132 T134 Q145 L148 L149 W152 V172 F173 G176 K177 G235 L236 K253 T254 S255 E256 K257 P258 P260 F261 F266 Q271 Y275 H305 S26 T28 Q39 L42 L43 W46 V66 F67 G70 K71 G122 L123 K140 T141 S142 E143 K144 P145 P147 F148 F153 Q158 Y162 H192 3.1.-.- Q9BQP7 RVPQNWFPIFNPEPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPQENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK 5zyt D 2.70 BS01 NUC H 1 Q126 S132 V133 T134 Q138 Q145 L149 W152 V172 F173 G176 H180 I234 G235 L236 D238 K253 T254 S255 E256 K257 K259 S264 F266 Y275 Q20 S26 V27 T28 Q32 Q39 L43 W46 V66 F67 G70 H74 I121 G122 L123 D125 K140 T141 S142 E143 K144 K146 S151 F153 Y162 3.1.-.- Q9BQP7 VPQNWFPIFNPERPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPQENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK 5zyu A 1.75 BS01 NUC E 1 S132 T134 Q138 Q145 L149 R151 W152 V172 F173 G176 K177 H180 I234 G235 L236 D238 K253 T254 S255 E256 K257 F266 Q271 Y275 S27 T29 Q33 Q40 L44 R46 W47 V67 F68 G71 K72 H75 I121 G122 L123 D125 K140 T141 S142 E143 K144 F153 Q158 Y162 3.1.-.- Q9BQP7 NWFPIFNPERSDKVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPQNLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKKNQN 5zyv A 2.72 BS01 NUC E 1 S132 T134 Q138 M141 Q145 L148 L149 R151 W152 V172 F173 G176 K177 I234 G235 L236 K253 T254 S255 E256 K257 F266 Q271 Y275 S4 T6 Q10 M13 Q17 L20 L21 R23 W24 V44 F45 G48 K49 I98 G99 L100 K117 T118 S119 E120 K121 F130 Q135 Y139 3.1.-.- Q9BQP7 VIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFQEALESILSDENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK 5zyv A 2.72 BS02 CA A 1 D238 D251 W252 D102 D115 W116 3.1.-.- Q9BQP7 VIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFQEALESILSDENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK 5zyv A 2.72 BS03 CA A 2 M279 N280 D282 Y285 M143 N144 D146 Y149 3.1.-.- Q9BQP7 VIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFQEALESILSDENLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKK 5zyw A 2.20 BS01 MN A 1 H180 L236 D238 E344 H78 L125 D127 E233 3.1.-.- Q9BQP7 QNWFPIFNPERSDKPSVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKKNQNIQKPEYSE 5zyw A 2.20 BS02 MN A 2 H180 D238 D251 W252 H78 D127 D140 W141 3.1.-.- Q9BQP7 QNWFPIFNPERSDKPSVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKKNQNIQKPEYSE 5zyw A 2.20 BS03 MN A 3 T134 K259 S343 E344 T32 K148 S232 E233 3.1.-.- Q9BQP7 QNWFPIFNPERSDKPSVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRMILELGEDGFKEYTSNVFLQGKRFHEALESILSPNLLKSGYIESVQHILKDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTKWLLRLEEYTEKKKNQNIQKPEYSE 5zz2 A 2.60 BS02 9M0 A 1 L725 L765 A767 I768 Q775 I778 A783 F786 F787 I813 Q817 F820 L181 L221 A223 I224 Q231 I234 A239 F242 F243 I252 Q256 F259 3.1.4.35 O76074 30148362 EETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGEKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQ 6acb A 2.80 BS03 9T9 A 1 V660 I768 A783 F786 F787 I813 M816 Q817 F820 V126 I234 A249 F252 F253 I261 M264 Q265 F268 3.1.4.35 O76074 30148362 EETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQEKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQ 6ae3 A 2.14 BS01 MRI A 1 G63 N64 V70 A83 K85 V110 L132 D133 Y134 V135 L188 C199 G28 N29 V35 A48 K50 V73 L94 D95 Y96 V97 L150 C161 2.7.11.26,2.7.11.1 Q9WV60 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQRFKNRELQIMRKLDHCNIVRLRYFFYSSGKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA 6ae3 A 2.14 BS02 MRI B 1 S261 G262 S223 G224 2.7.11.26,2.7.11.1 Q9WV60 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQRFKNRELQIMRKLDHCNIVRLRYFFYSSGKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAA 6ae3 B 2.14 BS01 MRI B 1 G63 F67 V70 A83 K85 V110 L132 D133 Y134 V135 L188 C199 D200 G28 F32 V35 A48 K50 V73 L94 D95 Y96 V97 L150 C161 D162 2.7.11.26,2.7.11.1 Q9WV60 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDFKNRELQIMRKLDHCNIVRLRYFFYSSEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARI 6aze A 2.45 BS01 III P 1 Y10 Y17 E19 S20 F22 Y23 I24 G25 C26 D27 W32 A45 I48 D49 Y4 Y11 E13 S14 F16 Y17 I18 G19 C20 D21 W26 A39 I42 D43 Q12830 TKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFK 6b1d A 2.51 BS01 QUE A 1 V37 E59 I66 V88 E131 K138 V36 E58 I65 V87 E130 K137 Q6VT83 GVFTFEDEITSTVPPAKLYNAMKDADSITPKIIDDVKSVEIVEGNGGPGTIKKLTIVEDGETKFILHKVESIDEANYAYNYSVVGGVALPPTAEKITFETKLVEGPNGGSIGKLTLKYHTKGDAKPDEEELKKGKAKGEGLFRAIEGYVLANPTQY 6b1d C 2.51 BS01 QUE C 1 V37 I57 E59 I66 H68 V88 E131 K138 V36 I56 E58 I65 H67 V87 E130 K137 Q6VT83 GVFTFEDEITSTVPPAKLYNAMKDADSITPKIIDDVKSVEIVEGNGGPGTIKKLTIVEDGETKFILHKVESIDEANYAYNYSVVGGVALPPTAEKITFETKLVEGPNGGSIGKLTLKYHTKGDAKPDEEELKKGKAKGEGLFRAIEGYVLANPTQY 6b1d C 2.51 BS02 BGC C 1 M23 K24 K53 I73 Y80 M22 K23 K52 I72 Y79 Q6VT83 GVFTFEDEITSTVPPAKLYNAMKDADSITPKIIDDVKSVEIVEGNGGPGTIKKLTIVEDGETKFILHKVESIDEANYAYNYSVVGGVALPPTAEKITFETKLVEGPNGGSIGKLTLKYHTKGDAKPDEEELKKGKAKGEGLFRAIEGYVLANPTQY 6b1r A 1.69 BS02 NUC G 1 L99 Q113 D114 L115 R116 L76 Q83 D84 L85 R86 2.7.7.49 P03355 30148365 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRSGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 6b1s A 2.00 BS02 NUC F 1 L99 Q113 D114 L115 R116 N119 G191 L76 Q82 D83 L84 R85 N88 G158 2.7.7.49 P03355 30148365 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 6b1s B 2.00 BS02 NUC F 1 Y64 L99 P100 R116 Y41 L76 P77 R86 2.7.7.49 P03355 30148365 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMSGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 6baf A 1.85 BS01 BLR A 1 C18 E21 Y177 Y199 F204 D208 I209 P210 A213 Y217 R253 V255 S256 I258 H259 Y262 M266 S271 S273 L285 C3 E6 Y162 Y184 F189 D193 I194 P195 A198 Y202 R238 V240 S241 I243 H244 Y247 M251 S256 S258 L270 Q097N3 TNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCTQVSGTRYVPYEVRTACEFLGEVMSSLLAA 6bak A 1.92 BS01 BLR A 1 C18 E21 I23 I175 Y177 Y199 F204 D208 I209 P210 A213 Y217 R253 V255 S256 I258 H259 Y262 M266 S271 S273 L285 S287 H289 C3 E6 I8 I160 Y162 Y184 F189 D193 I194 P195 A198 Y202 R238 V240 S241 I243 H244 Y247 M251 S256 S258 L270 S272 H274 Q097N3 TNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAA 6bao A 2.18 BS01 BLR A 1 C18 E21 I23 I175 Y177 Y199 F204 S207 D208 I209 P210 A213 Y217 R223 R253 V255 S256 I258 H259 Y262 M266 S271 S273 L285 A459 L469 C8 E11 I13 I165 Y167 Y189 F194 S197 D198 I199 P200 A203 Y207 R213 R243 V245 S246 I248 H249 Y252 M256 S261 S263 L275 A449 L459 Q097N3 QEVDLTNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCTQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSE 6bao B 2.18 BS01 BLR B 1 C18 I23 I175 Y177 Y199 F204 S207 D208 I209 P210 A213 Y217 I225 R253 V255 S256 I258 H259 Y262 S271 S273 L285 C8 I13 I165 Y167 Y189 F194 S197 D198 I199 P200 A203 Y207 I215 R243 V245 S246 I248 H249 Y252 S261 S263 L275 Q097N3 QEVDLTNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCTQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSE 6bap A 2.65 BS01 BLR A 1 C18 I23 Y177 V187 F204 S207 D208 I209 P210 A213 Y217 R253 V255 S256 I258 H259 Y262 S271 S273 S287 H289 A459 C8 I13 Y167 V177 F194 S197 D198 I199 P200 A203 Y207 R243 V245 S246 I248 H249 Y252 S261 S263 S277 H279 A449 Q097N3 QEVDLTNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSEEL 6bap B 2.65 BS01 BLR B 1 C18 E21 I23 I175 Y177 V187 F204 S207 D208 I209 P210 A213 Y217 I225 R253 V255 S256 I258 H259 Y262 S271 S273 S287 H289 A459 V460 C8 E11 I13 I165 Y167 V177 F194 S197 D198 I199 P200 A203 Y207 I215 R243 V245 S246 I248 H249 Y252 S261 S263 S277 H279 A449 V450 Q097N3 QEVDLTNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSEEL 6bap C 2.65 BS01 BLR C 1 C18 E21 I23 Y177 F204 S207 D208 I209 P210 Y217 R223 I225 R253 V255 S256 I258 H259 Y262 S271 M272 S273 L285 S287 H289 P471 C3 E6 I8 Y162 F189 S192 D193 I194 P195 Y202 R208 I210 R238 V240 S241 I243 H244 Y247 S256 M257 S258 L270 S272 H274 P456 Q097N3 TNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSEEL 6bay A 3.15 BS01 BLR A 1 C18 E21 I23 Y177 Y199 F204 S207 D208 I209 P210 A213 Y217 I225 R253 V255 S256 I258 H259 Y262 S271 S273 S287 H289 A459 C8 E11 I13 Y167 Y189 F194 S197 D198 I199 P200 A203 Y207 I215 R243 V245 S246 I248 H249 Y252 S261 S263 S277 H279 A449 Q097N3 QEVDLTNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSEEL 6bay C 3.15 BS01 BLR C 1 C18 E21 Y177 F204 D208 I209 P210 A213 Y217 R223 I225 R253 V255 I258 H259 Y262 S271 L285 S287 H289 A459 V460 P471 C3 E6 Y162 F189 D193 I194 P195 A198 Y202 R208 I210 R238 V240 I243 H244 Y247 S256 L270 S272 H274 A444 V445 P456 Q097N3 TNCDREPIHIPGAIQPHGVLLVLSEPGLVLTHASENAPAVLGNSAEQLLGAPLGHFIEPSVREPLEADLRSARLKQLNPLKVVWRVDGVDRFFDGIAHRHQGRLILELEPSSHREAVPFLSFFHAVRDGLSRLRDARDLQELCEAVVQEVRGLTGFDRAIIYRFDAEWNGSVIAEARDARADPYLGLHFPASDIPRQARELYQLNWLRIIPTIDYQPARVRALPGHGEPLDLSFSVLRSVSPIHLEYLHNMGVQASMSISLMKDGKLWGLISCHQVSGTRYVPYEVRTACEFLGEVMSSLLAAKEGNEDYDQRIRAKSIHAALLERMAREVDFVSGLASQESGLLELVHAHGAAIHFHGRTTVLGQAPSDEALTGLIEWLGSRTGEGVFCTDRLAREYPEAQAFQEVAAGLMAFSMSRGRNNFVLWFRPEAVQTVNWSGNPTKAVEFDQGGPRLHPRKSFELWKETVRGRCLPWKAYEVEAASELRRSIIDVALQRSEEL 6bih C 6.00 BS01 ADP C 1 G15 L16 K18 D157 G158 E214 K215 G302 M305 Y306 K336 G15 L16 K18 D157 G158 E214 K215 G302 M305 Y306 K336 P68135 29038012 DEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 6bih C 6.00 BS02 CA C 1 D154 S300 G301 R335 S338 V339 D154 S300 G301 R335 S338 V339 P68135 29038012 DEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 6btx A 3.20 BS01 CA A 1 D24 Q84 N196 E203 D21 Q67 N173 E180 Q6MLJ0 30082682 QSLLRIETQLLLGRLLTRSGDQAWDFVVPFALLVIFPGKLQVAAFYYLIVKIGTFLLTVVKWGVWLQFFAILAGMVFFGMLDGLVRAGGRESWLLSVLFIALALSGVMASLGSQITDISVSLVAPEKLTHFNSWLRRIDLATEVGAPILAGALFAFHPEQLPLAGLFLIGLWNLVSFVPEYFLLRNVISFSDPIFWLILSYALLWLSVLSPHGVLLAAYLKDEMRLPETEIGLFRGLGAVFGLISTVSFPYLVRRLGLISSSRWHLGFQGVTLGIAVTAFAMGSTASVYVFLGCILLSRVGLYGFSNGEFELRQRLIPEGRRGELNSLSSLTTTSATLILFSAGSLLPQTEDFKYLVYVSLAAVLLANVVFIKWSSR 6btx A 3.20 BS02 EDT A 1 W254 S256 S259 H261 G262 R348 L351 W205 S207 S210 H212 G213 R299 L302 Q6MLJ0 30082682 QSLLRIETQLLLGRLLTRSGDQAWDFVVPFALLVIFPGKLQVAAFYYLIVKIGTFLLTVVKWGVWLQFFAILAGMVFFGMLDGLVRAGGRESWLLSVLFIALALSGVMASLGSQITDISVSLVAPEKLTHFNSWLRRIDLATEVGAPILAGALFAFHPEQLPLAGLFLIGLWNLVSFVPEYFLLRNVISFSDPIFWLILSYALLWLSVLSPHGVLLAAYLKDEMRLPETEIGLFRGLGAVFGLISTVSFPYLVRRLGLISSSRWHLGFQGVTLGIAVTAFAMGSTASVYVFLGCILLSRVGLYGFSNGEFELRQRLIPEGRRGELNSLSSLTTTSATLILFSAGSLLPQTEDFKYLVYVSLAAVLLANVVFIKWSSR 6c48 A 2.32 BS01 III C 1 K372 Q401 Y404 A405 V408 L409 E412 N415 L418 N419 L422 K25 Q54 Y57 A58 V61 L62 E65 N68 L71 N72 L75 Q5TKA1 METLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYE 6c48 B 2.32 BS01 III C 1 Q88 Y92 G95 L96 E98 S99 M102 T103 G105 K106 L111 K113 Q26 Y30 G33 L34 E36 S37 M40 T41 G43 K44 L49 K51 Q52LA3 RDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK 6cw2 C 2.67 BS01 ZN C 1 C22 C25 H44 H48 C17 C20 H39 H43 HCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPILCPDWGADEELQLIKGAQTLGLGNWQDIADHIGSRGKEEVKEHYLKYYLESKYYPIPDIT 6cw2 C 2.67 BS02 ZN C 2 C7 C10 C31 C34 C2 C5 C26 C29 HCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPILCPDWGADEELQLIKGAQTLGLGNWQDIADHIGSRGKEEVKEHYLKYYLESKYYPIPDIT 6cw3 G 1.98 BS01 ZN G 1 C7 C10 C31 C34 C4 C7 C28 C31 Q02336 KFHCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPILADEELQLIKGGLGNWVKEHYLKYYLESKYYPIPD 6cw3 G 1.98 BS02 ZN G 2 C22 C25 H44 H48 C19 C22 H41 H45 Q02336 KFHCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPILADEELQLIKGGLGNWVKEHYLKYYLESKYYPIPD 6cx0 A 3.50 BS05 FJ7 A 1 F229 W232 Y251 F185 W188 Y207 Q94KI8 30190435 QKAAALVDLAEDGIGLPVEILDQSSESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDNKDEFADLCQAIALRFQKEEVPSLQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEK 6cyb A 1.62 BS02 FKV A 1 Y655 H656 T768 L770 T805 D808 L809 D811 Q812 I822 I826 F830 M847 Q859 F862 Y82 H83 T195 L197 T232 D235 L236 D238 Q239 I249 I253 F257 M274 Q286 F289 3.1.4.17 O00408 30128073 SLYKKAGFYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6cyb B 1.62 BS02 FKV B 1 Y655 H656 T768 L770 T805 D808 L809 D811 Q812 I822 I826 Q859 F862 Y86 H87 T199 L201 T236 D239 L240 D242 Q243 I253 I257 Q290 F293 3.1.4.17 O00408 30128073 STSLYKKAGFDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6cyc A 1.54 BS02 FKJ A 1 Y655 H656 T768 L770 T805 D808 L809 Q812 I826 Q859 F862 Y82 H83 T195 L197 T232 D235 L236 Q239 I253 Q286 F289 3.1.4.17 O00408 30128073 SLYKKAGFYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6cyd A 1.69 BS02 FKG A 1 Y655 H656 T768 L770 T805 D808 L809 Q812 I826 Y827 F830 M847 Q859 F862 Y82 H83 T195 L197 T232 D235 L236 Q239 I253 Y254 F257 M274 Q286 F289 3.1.4.17 O00408 30128073 SLYKKAGFYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6cyd B 1.69 BS02 FKG B 1 Y655 H656 T768 L770 T805 D808 L809 Q812 I822 I826 Y827 Q859 F862 Y87 H88 T200 L202 T237 D240 L241 Q244 I254 I258 Y259 Q291 F294 3.1.4.17 O00408 30128073 LSTSLYKKAGFDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6czh A 1.80 BS01 38E A 1 V14 M16 N18 S24 Q25 G26 Q27 M28 A42 Q43 I46 I52 Y72 I78 L104 V9 M11 N13 S19 Q20 G21 Q22 M23 A37 Q38 I41 I47 Y67 I73 L99 QLLPGTWQVTMTNEDGQTSQGQMHFQPRSPYTLDIVAQGTISDGRPITGYGKVTVKTDDTLHVNITYPSLGNIKVQGQITMDSPTQATWNSTTSDGKKLTGTLQR 6czh B 1.80 BS01 38E B 1 V14 N18 S24 Q25 G26 Q27 M28 A42 Q43 I46 I52 Y72 L75 I78 L104 V14 N18 S24 Q25 G26 Q27 M28 A42 Q43 I46 I52 Y72 L75 I78 L104 MSRAAQLLPGTWQVTMTNEDGQTSQGQMHFQPRSPYTLDIVAQGTISDGRPITGYGKVTVKTDDTLHVNITYPSLGNIKVQGQITMDSPTQATWNSTTSDGKKLTGTLQR 6czi B 2.30 BS01 38E B 1 V14 M16 N18 S24 Q25 G26 Q27 W28 A42 Q43 I46 I52 Y72 L104 V13 M15 N17 S23 Q24 G25 Q26 W27 A41 Q42 I45 I51 Y71 L103 SRAAQLLPGTWQVTMTNEDGQTSQGQWHFQPRSPYTLDIVAQGTISDGRPITGYGKATVKTDDTLHANLTYPSLGNIKAQGQITYDSPTQFTWNSTTSDGKKLTGTLQR 6d55 B 1.68 BS01 FWA B 1 V852 V875 M878 N879 V883 Y884 D887 F890 I893 L901 E902 H905 V275 V298 M301 N302 V306 Y307 D310 F313 I316 L324 E325 H328 Q07889 30205005 GQMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 6d56 B 1.68 BS01 FVM B 1 V852 V875 M878 N879 V883 Y884 L886 D887 F890 I893 K898 L901 E902 H905 V275 V298 M301 N302 V306 Y307 L309 D310 F313 I316 K321 L324 E325 H328 Q07889 30205005 GQMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 6d5e B 1.75 BS01 FVG B 1 V852 M878 N879 V883 Y884 D887 F890 I893 L901 H905 V275 M301 N302 V306 Y307 D310 F313 I316 L324 H328 Q07889 30205005 GQMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 6d5l B 1.70 BS01 FW7 B 1 V852 V875 M878 N879 V883 Y884 L886 D887 T889 F890 I893 L901 H905 V275 V298 M301 N302 V306 Y307 L309 D310 T312 F313 I316 L324 H328 Q07889 30205005 GQMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 6d5m S 2.08 BS01 FW4 S 1 V852 M878 V883 Y884 L886 D887 T889 F890 I893 L901 E902 H905 V274 M300 V305 Y306 L308 D309 T311 F312 I315 L323 E324 H327 Q07889 30205005 QMRLPSADVYRFAEPDSEENIIFEEGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIANITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPR 6d5p A 3.00 BS08 XYP A 1 Y46 Q108 G109 Y46 Q108 G109 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6d5p A 3.00 BS09 XYP A 2 A209 Y211 G212 A209 Y211 G212 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6d5r A 2.00 BS10 XYP A 3 Y46 S65 Y66 P69 H105 D124 G125 P132 Y46 S65 Y66 P69 H105 D124 G125 P132 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6d5u A 2.00 BS08 MOH A 1 R35 G36 N37 G38 Y81 N97 A98 R35 G36 N37 G38 Y81 N97 A98 3.4.24.27 P00800 ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTHYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQAFDAVGVK 6d66 A 2.23 BS01 GLY A 1 D482 M502 D480 M500 3.1.3.16,3.1.3.48 P28562 30198887 IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAHHHHH 6d66 A 2.23 BS02 GLY A 2 S435 E439 S433 E437 3.1.3.16,3.1.3.48 P28562 30198887 IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAHHHHH 6d66 B 2.23 BS01 DAL B 1 R31 Y69 R20 Y58 30198887 SDLGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLN 6d67 A 2.55 BS01 MAL A 1 N13 D15 K16 W63 A64 D66 R67 E112 E154 P155 Y156 F157 W231 W341 R345 N12 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 W340 R344 3.1.3.16,3.1.3.48 P28562 30198887 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAH 6d6f A 2.00 BS01 XYS A 1 N93 K96 N93 K96 3.2.1.17 P00698 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 6d8c H 3.54 BS01 III N 1 T194 R196 G197 Y198 S199 F200 E205 Q246 T190 R192 G193 Y194 S195 F196 E201 Q242 P68139 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 6d8c H 3.54 BS02 III P 1 E72 I75 T77 L110 P112 R177 E68 I71 T73 L106 P108 R173 P68139 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 6d8c H 3.54 BS03 ADP H 1 D11 G13 S14 G15 L16 K18 Q137 G156 D157 R210 K213 E214 G302 T303 M305 Y306 D7 G9 S10 G11 L12 K14 Q133 G152 D153 R206 K209 E210 G298 T299 M301 Y302 P68139 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 6d8c H 3.54 BS04 MG H 1 Q137 D154 G156 Q133 D150 G152 P68139 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 6dbz A 1.90 BS01 IPR A 1 A11 R27 I31 G40 G41 H42 E60 F78 Y87 F127 A6 R22 I26 G35 G36 H37 E55 F73 Y82 F122 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 30127411 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 6dbz A 1.90 BS02 MG A 1 G40 E56 E60 G35 E51 E55 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 30127411 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 6dbz A 1.90 BS03 MG A 2 G40 E60 G35 E55 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 30127411 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 6dbz B 1.90 BS01 IPR B 1 A11 R27 I31 G40 G41 H42 E60 N76 F78 Y87 K110 F127 A6 R22 I26 G35 G36 H37 E55 N71 F73 Y82 K105 F122 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 30127411 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 6dbz B 1.90 BS03 MG B 2 H42 E56 H37 E51 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 30127411 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 6dbz B 1.90 BS04 MG B 3 E56 E60 E51 E55 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 30127411 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 6dmx D 2.80 BS01 III C 1 D598 H602 L603 K606 R646 Y650 H651 L653 A654 E655 I657 Y658 Q661 D8 H12 L13 K16 R56 Y60 H61 L63 A64 E65 I67 Y68 Q71 2.3.1.48 P45481 WHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSR 6dmx B 2.80 BS01 III A 1 H602 K606 R646 Y650 H651 L653 A654 E655 I657 Y658 Q661 K662 E665 H14 K18 R58 Y62 H63 L65 A66 E67 I69 Y70 Q73 K74 E77 2.3.1.48 P45481 KGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL 6dnq D 2.35 BS01 III C 1 D598 L599 H602 L603 K606 L607 A610 R646 Y650 H651 L653 A654 E655 I657 Y658 Q661 K662 E665 D13 L14 H17 L18 K21 L22 A25 R61 Y65 H66 L68 A69 E70 I72 Y73 Q76 K77 E80 2.3.1.48 P45481 GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL 6drj A 3.30 BS01 APR A 1 T150 G151 G152 A153 K154 N155 T186 M191 Y271 R278 G309 P310 G311 T312 R334 T72 G73 G74 A75 K76 N77 T108 M113 Y193 R200 G231 P232 G233 T234 R256 CSLASWIKENIKKKECVRETPTDAFGDISFGGLGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAHVASVPVSKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTQQKLLKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQTSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYEPYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPFILLSHLILFIRGVFLRDLPQRHKNFRQELEQTEEEELLSWEAYMKDNYLASTRQDESQSVEHRIHDTAEKVGAMSELLEREQEMVDEEAPHMFARQLQYPDSTVRRFPVPEEKVSWEVNFSPYQPPVYNQQALDKHRNPGGRTGIRGKGALNTLGPNHILHPIFTRWRDAEHKVLEFLAVWEDAEKRWALLGGPAQPDEPLAQVLERILGKKLNEKTKTLLKAGEEVYKGYVDDSRNTDNAWVETSIITLHCDKNTPLMADLNHMVESSLSSHQPLQWREVSSDACRCSYQREALRQIAHHHNTYF 6drj A 3.30 BS02 CA A 1 E857 Q860 N883 D886 E1088 E718 Q721 N744 D747 E949 CSLASWIKENIKKKECVRETPTDAFGDISFGGLGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRDYTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAHVASVPVSKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTQQKLLKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQTSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQASDTVFYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILIENEERLNWIIRGAVYEPYITIFGNFPTNIDNTLFDISSCSVNASDPLKPKCPMLNADNTPVFPEWLTIMMLCVYLLFANILLLNLLIAIFNYTFQEVQDNTDTIWKFQRYELIKEYHSRPALPPPFILLSHLILFIRGVFLRDLPQRHKNFRQELEQTEEEELLSWEAYMKDNYLASTRQDESQSVEHRIHDTAEKVGAMSELLEREQEMVDEEAPHMFARQLQYPDSTVRRFPVPEEKVSWEVNFSPYQPPVYNQQALDKHRNPGGRTGIRGKGALNTLGPNHILHPIFTRWRDAEHKVLEFLAVWEDAEKRWALLGGPAQPDEPLAQVLERILGKKLNEKTKTLLKAGEEVYKGYVDDSRNTDNAWVETSIITLHCDKNTPLMADLNHMVESSLSSHQPLQWREVSSDACRCSYQREALRQIAHHHNTYF 6dt1 A 2.75 BS01 NUC B 1 Q44 Y46 I47 K48 K49 G162 A163 R164 S181 A183 N185 N258 L265 K266 F457 Q45 Y47 I48 K49 K50 G163 A164 R165 S182 A184 N186 N235 L242 K243 F434 6.5.1.1 P00970 30169742 HMILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHEQAEVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dt1 A 2.75 BS02 NUC C 1 G13 S14 T15 K16 K159 K365 K367 S407 G408 L409 K410 D411 K412 L458 I460 G14 S15 T16 K17 K160 K342 K344 S384 G385 L386 K387 D388 K389 L435 I437 6.5.1.1 P00970 30169742 HMILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHEQAEVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dt1 A 2.75 BS03 NUC D 1 R79 T82 G83 N84 G116 S118 V119 S120 I121 K124 T255 G259 N262 K263 T268 K361 Y380 H382 R383 K384 G390 N404 G406 S407 R422 K446 S447 D448 R450 K455 L456 F457 L458 P459 R80 T83 G84 N85 G117 S119 V120 S121 I122 K125 T232 G236 N239 K240 T245 K338 Y357 H359 R360 K361 G367 N381 G383 S384 R399 K423 S424 D425 R427 K432 L433 F434 L435 P436 6.5.1.1 P00970 30169742 HMILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHEQAEVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dt1 A 2.75 BS04 AMP C 1 Q157 L158 K159 A160 R164 E217 W282 I347 K349 K365 K367 Q158 L159 K160 A161 R165 E218 W259 I324 K326 K342 K344 6.5.1.1 P00970 30169742 HMILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHEQAEVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dt1 E 2.75 BS01 NUC F 1 Q44 Y46 K48 K49 G162 R164 S181 A183 N185 N258 N262 L265 F457 Q44 Y46 K48 K49 G162 R164 S181 A183 N185 N230 N234 L237 F429 6.5.1.1 P00970 30169742 MILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dt1 E 2.75 BS02 NUC G 1 G13 S14 T15 K16 R182 K365 K367 S407 L409 K410 D411 K412 L458 I460 G13 S14 T15 K16 R182 K337 K339 S379 L381 K382 D383 K384 L430 I432 6.5.1.1 P00970 30169742 MILKILNEIASIGSTKQKQAILEKNKDNELLKRVYRLTYSRGLQYYIKKWPKPGIATQSFGMLTLTDMLDFIEFTLATRKLTGNAAIEELTGYITDGKKDDVEVLRRVMMRDLECGASVSIANKVWPGLIPEQPQMLASSYDEKGINKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLGLDLLKEELIKMTAEARQIHPEGVLIDGELVYHVAESRTASNGIANKSLKGTISEKEAQCMKFQVWDYVPLVEIYSLPAFRLKYDVRFSKLEQMTSGYDKVILIENQVVNNLDEAKVIYKKYIDQGLEGIILKNIDGLWENARSKNLYKFKEVIDVDLKIVGIYPHRKDPTKAGGFILESECGKIKVNAGSGLKDKAGVKSHELDRTRIMENQNYYIGKILECECNGWLKSDGRTDYVKLFLPIAIRLREDKTKANTFEDVFGDFHEVTGL 6dtq A 2.15 BS01 MAL A 1 V29 E32 D59 R64 D85 F131 D133 Y182 E183 G184 E240 W258 Y260 G294 G295 W296 Q334 R367 V11 E14 D41 R46 D67 F113 D115 Y164 E165 G166 E222 W240 Y242 G276 G277 W278 Q316 R349 G4FGN8 AVKITMTSGGVGKELEVLKKQLEMFHQQYPDIEVEIIPMPDSSTERHDLYVTYFAAGETDPDVLMLDVIWPAEFAPFLEDLTADKDYFELGEFLPGTVMSVTVNGRIVAVPWFTDAGLLYYRKDLLEKYGYDHAPRTWDELVEMAKKISQAEGIHGFVWQGARYEGLVCDFLEYLWSFGGDVLDESGKVVIDSPEAVAALQFMVDLIYKHKVTPEGVTTYMEEDARRIFQNGEAVFMRNWPYAWSLVNSDESPIKGKVGVAPLPMGPGGRRAATLGGWVLGINKFSSPEEKEAAKKLIKFLTSYDQQLYKAINAGQNPTRKAVYKDPKLKEAAPFMVELLGVFINALPRPRVANYTEVSDVIQRYVHAALTRQTTSEDAIKNIAKELKFLL 6dtq A 2.15 BS02 MG A 1 T77 D78 D80 E308 T59 D60 D62 E290 G4FGN8 AVKITMTSGGVGKELEVLKKQLEMFHQQYPDIEVEIIPMPDSSTERHDLYVTYFAAGETDPDVLMLDVIWPAEFAPFLEDLTADKDYFELGEFLPGTVMSVTVNGRIVAVPWFTDAGLLYYRKDLLEKYGYDHAPRTWDELVEMAKKISQAEGIHGFVWQGARYEGLVCDFLEYLWSFGGDVLDESGKVVIDSPEAVAALQFMVDLIYKHKVTPEGVTTYMEEDARRIFQNGEAVFMRNWPYAWSLVNSDESPIKGKVGVAPLPMGPGGRRAATLGGWVLGINKFSSPEEKEAAKKLIKFLTSYDQQLYKAINAGQNPTRKAVYKDPKLKEAAPFMVELLGVFINALPRPRVANYTEVSDVIQRYVHAALTRQTTSEDAIKNIAKELKFLL 6dts A 1.50 BS01 MTT A 1 S12 E13 K14 F41 K45 A64 D66 W67 E111 N156 Y158 F159 W233 Q266 R303 M333 W343 S8 E9 K10 F37 K41 A60 D62 W63 E107 N152 Y154 F155 W229 Q262 R299 M329 W339 Q9S5Y1 TKLTIWCSEKQVDILQKLGEEFKAKYGIPVEVQYVDFGSIKSKFLTAAPQGQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNFYDTALKAFSYGGKLYGVPYAMEAVALIYNKDYVDSVPKTMDELIEKAKQIDEEYGGEVRGFIYDVANFYFSAPFILGYGGYVFKETPQGLDVTDIGLANEGAVKGAKLIKRMIDEGVLTPGDNYGTMDSMFKEGLAAMIINGLWAIKSYKDAGINYGVAPIPELEPGVPAKPFVGVQGFMINAKSPNKVIAMEFLTNFIARKETMYKIYLADPRLPARKDVLELVKDNPDVVAFTQSASMGTPMPNVPEMAPVWSAMGDALSIIINGQASVEDALKEAVEKIKAQIEKGSHHHH 6dtu A 1.50 BS01 MTT A 1 S12 K14 F41 Q42 K45 A64 D66 W67 E111 E156 Y158 Y159 Y213 W233 Q266 R303 W343 S10 K12 F39 Q40 K43 A62 D64 W65 E109 E154 Y156 Y157 Y211 W231 Q264 R301 W341 Q9X0T1 MQPKLTIWCSEKQVDILQKLGEEFKAKYGVEVEVQYVNFQDIKSKFLTAAPEGQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNFYETALNAFSYGGKLYGIPYAMEAIALIYNKDYVPEPPKTMDELIEIAKQIDEEFGGEVRGFITSAAEFYYIAPFIFGYGGYVFKQTEKGLDVNDIGLANEGAIKGVKLLKRLVDEGILDPSDNYQIMDSMFREGQAAMIINGPWAIKAYKDAGIDYGVAPIPDLEPGVPARPFVGVQGFMVNAKSPNKLLAIEFLTSFIAKKETMYRIYLGDPRLPSRKDVLELVKDNPDVVGFTLSAANGIPMPNVPQMAAVWAAMNDALNLVVNGKATVEEALKNAVERIKAQIQS 6dtu B 1.50 BS01 MTT B 1 S12 K14 F41 Q42 K45 A64 D66 W67 E111 Y158 Y159 W233 Q266 R303 M333 W343 S10 K12 F39 Q40 K43 A62 D64 W65 E109 Y156 Y157 W231 Q264 R301 M331 W341 Q9X0T1 MQPKLTIWCSEKQVDILQKLGEEFKAKYGVEVEVQYVNFQDIKSKFLTAAPEGQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNFYETALNAFSYGGKLYGIPYAMEAIALIYNKDYVPEPPKTMDELIEIAKQIDEEFGGEVRGFITSAAEFYYIAPFIFGYGGYVFKQTEKGLDVNDIGLANEGAIKGVKLLKRLVDEGILDPSDNYQIMDSMFREGQAAMIINGPWAIKAYKDAGIDYGVAPIPDLEPGVPARPFVGVQGFMVNAKSPNKLLAIEFLTSFIAKKETMYRIYLGDPRLPSRKDVLELVKDNPDVVGFTLSAANGIPMPNVPQMAAVWAAMNDALNLVVNGKATVEEALKNAVERIKAQIQ 6dww A 2.85 BS01 NUC B 1 P108 F109 S110 K372 Q375 T376 C377 S378 R573 S576 K605 P28 F29 S30 K292 Q295 T296 C297 S298 R447 S450 K479 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dww A 2.85 BS02 NUC C 1 W182 T183 R218 S219 T220 A221 A251 N252 K255 H268 S309 S310 K312 T317 R318 W319 Q375 E572 S576 W102 T103 R138 S139 T140 A141 A171 N172 K175 H188 S229 S230 K232 T237 R238 W239 Q295 E446 S450 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dww A 2.85 BS03 NUC D 1 D248 R249 A251 H268 N272 D168 R169 A171 H188 N192 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dww A 2.85 BS04 MN A 1 D180 D248 D100 D168 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dww A 2.85 BS05 MN A 2 D180 L181 E572 F575 D100 L101 E446 F449 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwy A 3.20 BS02 NUC C 1 D180 W182 T183 R218 T220 A221 A251 N252 K255 H268 R308 S309 S310 K312 T317 R318 W319 Q375 E572 R573 S576 D100 W102 T103 R138 T140 A141 A171 N172 K175 H188 R228 S229 S230 K232 T237 R238 W239 Q295 E446 R447 S450 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwy A 3.20 BS03 NUC D 1 D248 R249 N272 D168 R169 N192 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz A 3.20 BS01 NUC B 1 P108 F109 S110 P28 F29 S30 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz A 3.20 BS02 NUC C 1 K92 L181 T183 R218 S219 T220 A221 A251 K255 S309 S310 K312 C315 P316 K12 L101 T103 R138 S139 T140 A141 A171 K175 S229 S230 K232 C235 P236 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz A 3.20 BS03 NUC D 1 D248 R249 A251 N272 D168 R169 A171 N192 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz A 3.20 BS04 NUC F 1 R107 I145 S148 K585 R586 N587 R588 I589 G590 T593 R27 I65 S68 K452 R453 N454 R455 I456 G457 T460 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz A 3.20 BS05 NUC G 1 L141 P142 S143 I145 T146 R149 Y186 K300 E584 N587 R588 L61 P62 S63 I65 T66 R69 Y106 K220 E451 N454 R455 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz E 3.20 BS02 NUC C 1 P142 S143 I145 T146 R149 K300 E584 N587 R588 P62 S63 I65 T66 R69 K220 E451 N454 R455 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz E 3.20 BS04 NUC G 1 K91 K92 I95 L181 T183 R218 T220 A221 E222 N252 K255 S310 K312 S313 C315 T317 K11 K12 I15 L101 T103 R138 T140 A141 E142 N172 K175 S230 K232 S233 C235 T237 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dwz E 3.20 BS05 NUC H 1 D248 R249 G250 N272 D168 R169 G170 N192 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dx0 A 2.90 BS02 NUC C 1 D180 W182 R218 S219 T220 A221 N252 K255 H268 S310 K312 R318 W319 Q375 E572 R573 S576 D100 W102 R138 S139 T140 A141 N172 K175 H188 S230 K232 R238 W239 Q295 E446 R447 S450 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dx0 A 2.90 BS03 NUC D 1 D248 R249 G250 A251 H268 N272 D168 R169 G170 A171 H188 N192 Q25438 RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINRMSSFPVSPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK 6dzk S 3.60 BS01 III g 1 L5 I41 P42 E64 V67 L4 I40 P41 E63 V66 A0QSD5 PRSLKKGPFVDDHLLKKVDVQNEKNTKQVIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTEAMVGHKLGEFAPTRTFKGH 6e0d A 2.24 BS01 XXX A 1 G81 R82 P83 K106 G81 R82 P83 K106 P02883 30198893 ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTKGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMDFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPT 6e1k A 3.30 BS01 CA A 1 E374 D376 E344 D346 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSR 6e1k A 3.30 BS02 CA A 2 D335 D337 N339 E341 D305 D307 N309 E311 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSR 6e1m A 3.30 BS03 3PH A 1 F79 F83 F87 I199 R200 E201 M566 G570 F58 F62 F66 I169 R170 E171 M395 G399 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSR 6e1m B 3.30 BS01 CA B 1 E374 R379 E344 R349 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSR 6e1m B 3.30 BS03 3PH B 1 F79 F87 I199 R200 E201 L202 M566 P567 G570 F58 F66 I169 R170 E171 L172 M395 P396 G399 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSR 6e1n A 3.70 BS01 CA A 1 F368 D376 F335 D343 Q94KI8 30190435 EAIHGPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLNIEVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETAQWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDS 6e1n A 3.70 BS03 3PH A 1 F79 F87 I199 R200 E201 R498 M566 G570 F573 F55 F63 I166 R167 E168 R456 M510 G514 F517 Q94KI8 30190435 EAIHGPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLNIEVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETAQWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDS 6e1n B 3.70 BS02 3PH B 1 F79 F83 F87 I199 R200 E201 R498 M566 L569 G570 F573 F55 F59 F63 I166 R167 E168 R456 M510 L513 G514 F517 Q94KI8 30190435 EAIHGPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLNIEVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETAQWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDS 6e1p A 3.70 BS01 CA A 1 K365 D376 R379 D380 K335 D346 R349 D350 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSPNFGYAISFILIINFIAVVVETTLNIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGQWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQ 6e1p A 3.70 BS02 CA A 2 D335 D337 N339 E341 I342 Q346 D305 D307 N309 E311 I312 Q316 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSPNFGYAISFILIINFIAVVVETTLNIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGQWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQ 6e1p B 3.70 BS01 CA B 1 K365 F368 D376 R379 D380 K335 F338 D346 R349 D350 Q94KI8 30190435 SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSPNFGYAISFILIINFIAVVVETTLNIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPFSNGQWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQ 6e2m A 2.25 BS01 KK7 A 1 L686 G689 A707 K709 V738 M754 E755 Q756 V757 G760 L810 S821 D822 L17 G20 A38 K40 V64 M79 E80 Q81 V82 G85 L135 S146 D147 2.7.11.25 Q99683 30024858 LLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPYSQPLHEEIALHKHLKHKNIVQYLGSFSENFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLK 6e2n A 2.10 BS01 KK8 A 1 L686 G689 V694 A707 K709 V738 M754 E755 Q756 V757 G759 G760 D807 N808 L810 S821 D822 L17 G20 V25 A38 K40 V66 M82 E83 Q84 V85 G87 G88 D135 N136 L138 S149 D150 2.7.11.25 Q99683 30024858 LLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLK 6e2o A 2.39 BS01 S0L A 1 L686 G689 A707 K709 V738 M754 E755 Q756 V757 P758 G759 D807 N808 L810 S821 D822 L17 G20 A38 K40 V67 M83 E84 Q85 V86 P87 G88 D136 N137 L139 S150 D151 2.7.11.25 Q99683 30024858 LLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPESRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLACTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLK 6e3y R 3.30 BS01 III P 1 D90 Q93 V135 A138 L139 L141 F142 L195 A199 Q202 H219 L220 M223 S286 D287 Y292 H295 C299 W354 M369 H370 M373 D49 Q52 V91 A94 L95 L97 F98 L151 A155 Q158 H175 L176 M179 S242 D243 Y248 H251 C255 W305 M313 H314 M317 Q16602 QLGVTRNKIMTAQYECYQKIMQYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTNLYMKAVRATLILVPLLGIEFVLIPWREVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQY 6e3y R 3.30 BS02 III P 2 D70 W72 F92 D94 F95 H114 A116 S117 R119 W121 T122 Y124 T125 N128 D29 W31 F51 D53 F54 H70 A72 S73 R75 W77 T78 Y80 T81 N84 Q16602 QLGVTRNKIMTAQYECYQKIMQYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTNLYMKAVRATLILVPLLGIEFVLIPWREVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQY 6e3y E 3.30 BS01 III P 3 W84 P85 W56 P57 O60894 EANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPITVTLLVTALVVWQSKR 6e6q B 1.20 BS01 FES B 1 C4 L5 C6 G35 T36 Q37 C38 G39 C41 C4 L5 C6 G35 T36 Q37 C38 G39 C41 A0A069Q647 30183257 MYVCLCQGVTDNQIRDAIYEGCCSYREVREATGVGTQCGKCASLAKQVVRETLNDL 6e6s A 1.45 BS01 FES A 1 C4 L5 C6 G35 T36 Q37 C38 C41 C4 L5 C6 G35 T36 Q37 C38 C41 A0A069Q647 30183257 MYVCLCQGVTDNQIRDAIYEGCCSYEEVREATGVGTQCGKCASLAYQVVRETLNDL 6e6s B 1.45 BS01 FES B 1 C4 L5 C6 G35 Q37 C38 C41 C4 L5 C6 G35 Q37 C38 C41 A0A069Q647 30183257 MYVCLCQGVTDNQIRDAIYEGCCSYEEVREATGVGTQCGKCASLAYQVVRETLNDL 6e83 B BS01 III A 1 V819 G820 F821 K822 D824 E829 S846 L847 D848 V9 G10 F11 K12 D14 E19 S36 L37 D38 Q8IYH5 GPLGSVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPIYR 6e83 B BS02 ZN B 1 C823 C826 C850 C853 C13 C16 C40 C43 Q8IYH5 GPLGSVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPIYR 6e83 B BS03 ZN B 2 C838 C841 H863 H867 C28 C31 H53 H57 Q8IYH5 GPLGSVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPIYR 6e86 B BS01 III A 1 V819 G820 F821 K822 D824 E844 M845 S846 D848 V9 G10 F11 K12 D14 E34 M35 S36 D38 Q8IYH5 GPLGSVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPIYR 6ebo A 1.58 BS01 CA A 1 G263 D266 E267 G260 D263 E264 1.17.4.1 F2I8X9 NYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIKNSLTEQEQVIYANFAFMVGVHARSYGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLSARADENHDF 6ebq A 1.95 BS01 FMN A 1 S9 T10 S12 N13 N14 T15 P48 T49 Y50 S51 G52 G53 G91 N92 F95 S98 F99 A100 L120 S7 T8 S10 N11 N12 T13 P46 T47 Y48 S49 G50 G51 G89 N90 F93 S96 F97 A98 L118 A0A178HGH7 ELIVYFSTQSNNTHRFVQKLDAESIRIPIDEEERIKVDEDYVLIVPTYSGGKVTDAGQVDAHGAVPKQVIHFLNDPDNRKHCLGVISSGNTNFGDSFAIAGPVISYKLKVPLLYQFELIGTKEDVEEVNRIISETFNA 6ebq B 1.95 BS01 FMN B 1 S9 T10 S12 N13 N14 T15 P48 T49 Y50 S51 G91 N92 F95 S98 F99 A100 L120 S5 T6 S8 N9 N10 T11 P44 T45 Y46 S47 G75 N76 F79 S82 F83 A84 L104 A0A178HGH7 IVYFSTQSNNTHRFVQKLDAESIRIPIDEEERIKVDEDYVLIVPTYSGGAVPKQVIHFLNDPDNRKHCLGVISSGNTNFGDSFAIAGPVISYKLKVPLLYQFELIGTKEDVEEVNRIISETFN 6ebz A 1.66 BS01 CA A 1 G263 E267 G259 E263 1.17.4.1 F2I8X9 NYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIKNSLTEQEQVIYANFAFMVGVHARSGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLSARADENHDFF 6ebz B 1.66 BS01 SCN B 1 F241 L244 P288 F237 L240 P284 1.17.4.1 F2I8X9 NYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIKNSLTEQEQVIYANFAFMVGVHARSGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLS 6ebz B 1.66 BS02 SCN B 2 L84 D85 Q88 V116 M175 P176 L180 K210 L81 D82 Q85 V113 M171 P172 L176 K206 1.17.4.1 F2I8X9 NYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIKNSLTEQEQVIYANFAFMVGVHARSGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLS 6ebz B 1.66 BS03 SCN B 3 Y5 N28 K31 Y2 N25 K28 1.17.4.1 F2I8X9 NYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIKNSLTEQEQVIYANFAFMVGVHARSGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLS 6ebz C 1.66 BS01 SCN C 1 D260 G263 A265 D266 E267 D256 G259 A261 D262 E263 1.17.4.1 F2I8X9 NYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIKNSLTEQEQVIYANFAFMVGVHARSGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLSA 6eei A 1.99 BS01 PHE A 1 W82 Y90 Y91 H193 K309 W75 Y83 Y84 H186 K302 4.1.1.25 Q8RY79 VLKPMDSEQLREYGHLMVDFIADYYKTIEDFPVLSQVQPGYLHKLLPDSAPDHPETLDQVLDDVRAKILPGVTHWQSPSFFAYYPSNSSVAGFLGEMLSAGLGIVGFSWVTSPAATELEMIVLDWVAKLLNLPEQFMSKGNGGGVIQGSASEAVLVVLIAARDKVLRSVGKNALEKLVVYSSDQTHSALQKACQIAGIHPENCRVLTTDSSTNYALRPESLQEAVSRDLEAGLIPFFLCANVGTTSSTAVDPLAALGKIANSNGIWFHVDAAYAGSACICPEYRQYIDGVETADSFNMNAHKWFLTNFDCSLLWVKDQDSLTLALSTNPLVVDYKDWQIPLGRRFRSLKLWMVLRLYGSETLKSYIRNHIKLAKEFEQLVSQDPNFEIVTPRIFALVCFRLVPVKCNNRNRELLDAVNSSGKLFMSHTALSGKIVLRCAIGAPLTEEKHVKEAWKIIQEEASYLLH 6eei A 1.99 BS02 PHE B 1 F114 L359 F107 L341 4.1.1.25 Q8RY79 VLKPMDSEQLREYGHLMVDFIADYYKTIEDFPVLSQVQPGYLHKLLPDSAPDHPETLDQVLDDVRAKILPGVTHWQSPSFFAYYPSNSSVAGFLGEMLSAGLGIVGFSWVTSPAATELEMIVLDWVAKLLNLPEQFMSKGNGGGVIQGSASEAVLVVLIAARDKVLRSVGKNALEKLVVYSSDQTHSALQKACQIAGIHPENCRVLTTDSSTNYALRPESLQEAVSRDLEAGLIPFFLCANVGTTSSTAVDPLAALGKIANSNGIWFHVDAAYAGSACICPEYRQYIDGVETADSFNMNAHKWFLTNFDCSLLWVKDQDSLTLALSTNPLVVDYKDWQIPLGRRFRSLKLWMVLRLYGSETLKSYIRNHIKLAKEFEQLVSQDPNFEIVTPRIFALVCFRLVPVKCNNRNRELLDAVNSSGKLFMSHTALSGKIVLRCAIGAPLTEEKHVKEAWKIIQEEASYLLH 6eei B 1.99 BS02 PHE B 1 Y90 Y91 T252 K309 Y83 Y84 T245 K302 4.1.1.25 Q8RY79 VLKPMDSEQLREYGHLMVDFIADYYKTIEDFPVLSQVQPGYLHKLLPDSAPDHPETLDQVLDDVRAKILPGVTHWQSPSFFAYYPSNSSVAGFLGEMLSAGLGIVGFSWVTSPAATELEMIVLDWVAKLLNLPEQFMSKGNGGGVIQGSASEAVLVVLIAARDKVLRSVGKNALEKLVVYSSDQTHSALQKACQIAGIHPENCRVLTTDSSTNYALRPESLQEAVSRDLEAGLIPFFLCANVGTTSSTAVDPLAALGKIANSNGIWFHVDAAYAGSACICPEYRQYIDGVETADSFNMNAHKWFLTNFDCSLLWVKDQDSLTLALSTNPEFLLVVDYKDWQIPLGRRFRSLKLWMVLRLYGSETLKSYIRNHIKLAKEFEQLVSQDPNFEIVTPRIFALVCFRLVPVKDECNNRNRELLDAVNSSGKLFMSHTALSGKIVLRCAIGAPLTEEKHVKEAWKIIQEEASYLLH 6eem A 2.61 BS01 0PR A 1 W90 Y98 F99 P100 T168 T169 C170 H205 T260 T264 D289 A291 N318 H320 K321 L327 W74 Y82 F83 P84 T150 T151 C152 H187 T242 T246 D271 A273 N300 H302 K303 L309 4.1.1.28 O82415 QNPLDPDEFRRQGHMIIDFLADYYKNVEKYPVRSQVEPGYLKKRLPESAPYNPESIETILEDVTNDIIPGLTHWQSPNYFAYFPSSGSIAGFLGEMLSTGFNVVGFNWMSSPAATELESIVMNWLGQMLTLPKSFLFSSDGGGGGVLQGTTCEAILCTLTAARDKMLNKIGRENINKLVVYASDQTHCALQKAAQIAGINPKNVRAIKTSKATNFGLSPNSLQSAILADIESGLVPLFLCATVGTTSSTAVDPIGPLCAVAKLYGIWVHIDAAYAGSACICPEFRHFIDGVEDADSFSLNAHKWFFTTLDCCCLWVKDSDSLVKALSTSPEYLKNQVIDYKDWQIALSRRFRSMKLWLVLRSYGVANLRTFLRSHVKMAKHFQGLIGMDNRFEIVVPRTFAMVCFRLKPTAIFKQKIVDNDYIEDQTNEVNVKLLESVNASGKIYMTHAVVGGVYMIRFAVGATLTEERHVTGAWKVVQEHTDAILG 6eem A 2.61 BS02 TYR B 1 V120 F122 Y350 L371 S372 V104 F106 Y332 L347 S348 4.1.1.28 O82415 QNPLDPDEFRRQGHMIIDFLADYYKNVEKYPVRSQVEPGYLKKRLPESAPYNPESIETILEDVTNDIIPGLTHWQSPNYFAYFPSSGSIAGFLGEMLSTGFNVVGFNWMSSPAATELESIVMNWLGQMLTLPKSFLFSSDGGGGGVLQGTTCEAILCTLTAARDKMLNKIGRENINKLVVYASDQTHCALQKAAQIAGINPKNVRAIKTSKATNFGLSPNSLQSAILADIESGLVPLFLCATVGTTSSTAVDPIGPLCAVAKLYGIWVHIDAAYAGSACICPEFRHFIDGVEDADSFSLNAHKWFFTTLDCCCLWVKDSDSLVKALSTSPEYLKNQVIDYKDWQIALSRRFRSMKLWLVLRSYGVANLRTFLRSHVKMAKHFQGLIGMDNRFEIVVPRTFAMVCFRLKPTAIFKQKIVDNDYIEDQTNEVNVKLLESVNASGKIYMTHAVVGGVYMIRFAVGATLTEERHVTGAWKVVQEHTDAILG 6eem B 2.61 BS02 TYR B 1 W90 Y98 F99 P100 S101 H205 T264 H320 K321 W74 Y82 F83 P84 S85 H187 T246 H302 K303 4.1.1.28 O82415 QNPLDPDEFRRQGHMIIDFLADYYKNVEKYPVRSQVEPGYLKKRLPESAPYNPESIETILEDVTNDIIPGLTHWQSPNYFAYFPSSGSIAGFLGEMLSTGFNVVGFNWMSSPAATELESIVMNWLGQMLTLPKSFLFSSDGGGGGVLQGTTCEAILCTLTAARDKMLNKIGRENINKLVVYASDQTHCALQKAAQIAGINPKNVRAIKTSKATNFGLSPNSLQSAILADIESGLVPLFLCATVGTTSSTAVDPIGPLCAVAKLYGIWVHIDAAYAGSACICPEFRHFIDGVEDADSFSLNAHKWFFTTLDCCCLWVKDSDSLVKALSTSPEYLKNKQVIDYKDWQIALSRRFRSMKLWLVLRSYGVANLRTFLRSHVKMAKHFQGLIGMDNRFEIVVPRTFAMVCFRLKPTAIFKQKIVDNDYIEDQTNEVNVKLLESVNASGKIYMTHAVVGGVYMIRFAVGATLTEERHVTGAWKVVQEHTDAILG 6eew A 2.05 BS01 TRP A 1 F100 F101 T262 H318 K319 F82 F83 T244 H300 K301 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNPEYLKNKQSDLDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDLL 6eew A 2.05 BS02 CA A 1 D397 T477 D379 T459 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNPEYLKNKQSDLDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDLL 6eew A 2.05 BS03 TRP B 1 F124 T369 F106 T351 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNPEYLKNKQSDLDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDLL 6eew B 2.05 BS01 TRP A 1 V122 T369 V104 T340 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDLL 6eew B 2.05 BS02 TRP B 1 W92 F100 F101 H318 K319 W74 F82 F83 H300 K301 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDLL 6eew C 2.05 BS01 TRP C 1 W92 F100 F101 H203 T262 H318 K319 W74 F82 F83 H185 T244 H300 K301 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDL 6eew C 2.05 BS03 TRP D 1 V122 F124 T369 V104 F106 T340 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTNDKVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDL 6eew D 2.05 BS02 TRP D 1 W92 F100 T262 H318 K319 W74 F82 T244 H300 K301 4.1.1.28 P17770 FKPLEAEEFRKQAHRMVDFIADYYKNVETYPVLSEVEPGYLRKRIPETAPYLPEPLDDIMKDIQKDIIPGMTNWMSPNFYAFFPATVSSAAFLGEMLSTALNSVGFTWVSSPAATELEMIVMDWLAQILKLPKSFMFSGTGGGVIQNTTSESILCTIIAARERALEKLGPDSIGKLVCYGSDQTHTMFPKTCKLAGIYPNNIRLIPTTVETDFGISPQVLRKMVEDDVAAGYVPLFLCATLGTTSTTATDPVDSLSEIANEFGIWIHVDAAYAGSACICPEFRHYLDGIERVDSLSLSPHKWLLAYLDCTCLWVKQPHLLLRALTTVVDFKNWQIATGRKFRSLKLWLILRSYGVVNLQSHIRSDVAMAKMFEEWVRSDSRFEIVVPRNFSLVCFRLKPDVSSLHVEEVNKKLLDMLNSTGRVYMTHTIVGGIYMLRLAVGSSLTEEHHVRRVWDLIQKLTDDL 6eqm A 1.35 BS01 BUH A 1 G11 Q12 G13 Y14 L30 D32 S35 Y71 F108 I110 W115 I118 D228 S229 G230 T231 T232 A335 G14 Q15 G16 Y17 L33 D35 S38 Y74 F111 I113 W118 I121 D221 S222 G223 T224 T225 A328 3.4.23.46 P56817 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 6exi A 1.92 BS01 ADN A 1 L57 H58 T60 Q62 T63 D231 H342 N385 L386 G391 H392 M397 F401 L52 H53 T55 Q57 T58 D226 H337 N380 L381 G386 H387 M392 F396 3.3.1.1 A0A087WNH6 29619018 GFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDTAFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASLRNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKQEGPYKSDHYRY 6exi A 1.92 BS02 ADN A 2 G263 S283 E284 V285 D286 C289 T317 N319 I322 G258 S278 E279 V280 D281 C284 T312 N314 I317 3.3.1.1 A0A087WNH6 29619018 GFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDTAFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASLRNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKQEGPYKSDHYRY 6exi C 1.92 BS01 ADN C 1 L57 H58 T60 Q62 T63 D231 N232 H342 L383 N385 L386 G391 H392 M397 F401 L52 H53 T55 Q57 T58 D226 N227 H337 L378 N380 L381 G386 H387 M392 F396 3.3.1.1 A0A087WNH6 29619018 GFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDTAFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASLRNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKQEGPYKSDHYRY 6exi C 1.92 BS02 ADN C 2 G263 E284 V285 D286 C289 T317 N319 I322 G258 E279 V280 D281 C284 T312 N314 I317 3.3.1.1 A0A087WNH6 29619018 GFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDTAFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASLRNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKQEGPYKSDHYRY 6exi D 1.92 BS02 ADN D 2 S283 E284 V285 D286 C289 T317 N319 I322 S278 E279 V280 D281 C284 T312 N314 I317 3.3.1.1 A0A087WNH6 29619018 GFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDTAFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASLRNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKQEGPYKSDHYRY 6f32 A 2.80 BS01 FAD A 1 V13 G14 G16 G17 S18 F35 E36 A37 G42 G43 H44 G62 V63 E64 H65 V228 H257 V260 W362 L364 G391 T392 G398 H399 A402 V13 G14 G16 G17 S18 F35 E36 A37 G42 G43 H44 G62 V63 E64 H65 V224 H253 V256 W358 L360 G387 T388 G394 H395 A398 Q83X90 MTVVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSYKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 A 2.80 BS02 CJ8 A 1 Y168 L185 L191 W200 L364 T397 G398 Y164 L181 L187 W196 L360 T393 G394 Q83X90 MTVVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSYKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 A 2.80 BS03 CA A 1 E111 E114 E111 E114 Q83X90 MTVVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSYKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 A 2.80 BS04 CA A 2 S188 N190 S184 N186 Q83X90 MTVVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSYKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 B 2.80 BS01 FAD B 1 V13 G14 G16 S18 F35 E36 A37 G42 G43 H44 G62 V63 E64 H65 V228 T256 H257 V260 F345 W362 L364 G391 T392 G398 H399 A402 V11 G12 G14 S16 F33 E34 A35 G40 G41 H42 G60 V61 E62 H63 V221 T249 H250 V253 F338 W355 L357 G384 T385 G391 H392 A395 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 B 2.80 BS02 CA B 1 G301 V330 G294 V323 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 B 2.80 BS03 CA B 2 S166 I167 Y168 G170 S159 I160 Y161 G163 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f32 B 2.80 BS04 CJE B 1 Y168 Y182 T397 Y161 Y175 T390 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f5p A 4.14 BS01 III G 1 P237 I238 K239 Y241 N659 S661 F663 R701 G702 K704 P237 I238 K239 Y241 N659 S661 F663 R701 G702 K704 3.1.-.- Q9IMP5 29910112 MSKTFAEIAEAFLEPEAVRIAKEAVEEYGDHERKIIQIGIHFQVCCMFCDEYLSTNGSDRFVLIEGRKRGTAVSLQNELCKSYDLEPLPFLCDIFDREEKQFVEIGITRKADDSYFQSKFGKLGNSCKIFVFSYDGRLDKNCEGPMEEQKLRIFSFLATAADFLRKENMFNEIFLPDNEETIIEMKKGKTFLELRDESVPLPFQTYEQMKDYCEKFKGNPRELASKVSQMQSNIKLPIKHYEQNKFRQIRLPKGPMAPYTHKFLMEEAWMFTKISDPERSRAGEILIDFFKKGNLSAIRPKDKPLQGKYPIHYKNLWNQIKAAIADRTMVINENDHSEFLGGIGRASKKIPEISLTQDVITTEGLKQSENKLPEPRSFPRWFNAEWMWAIKDSDLTGWVPMAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVGALMTECRLFPGKIKVVPIYARSKERKSMQEGLPVPSEMDCLFGICVKSKSHLNKDDGMYTIITFEFSIREPNLEKHQKYTVFEAGHTTVRMKKGESVIGREVPLYLYCRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTLNEKQMWIGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKILMALEGDKKNKSSFGFNPEGLLEKIEECLINNPMCLFMAQRLNELVIEASKRGAKFFKT 6f5p A 4.14 BS02 III H 1 W269 M270 F271 T272 D394 V532 W269 M270 F271 T272 D394 V532 3.1.-.- Q9IMP5 29910112 MSKTFAEIAEAFLEPEAVRIAKEAVEEYGDHERKIIQIGIHFQVCCMFCDEYLSTNGSDRFVLIEGRKRGTAVSLQNELCKSYDLEPLPFLCDIFDREEKQFVEIGITRKADDSYFQSKFGKLGNSCKIFVFSYDGRLDKNCEGPMEEQKLRIFSFLATAADFLRKENMFNEIFLPDNEETIIEMKKGKTFLELRDESVPLPFQTYEQMKDYCEKFKGNPRELASKVSQMQSNIKLPIKHYEQNKFRQIRLPKGPMAPYTHKFLMEEAWMFTKISDPERSRAGEILIDFFKKGNLSAIRPKDKPLQGKYPIHYKNLWNQIKAAIADRTMVINENDHSEFLGGIGRASKKIPEISLTQDVITTEGLKQSENKLPEPRSFPRWFNAEWMWAIKDSDLTGWVPMAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVGALMTECRLFPGKIKVVPIYARSKERKSMQEGLPVPSEMDCLFGICVKSKSHLNKDDGMYTIITFEFSIREPNLEKHQKYTVFEAGHTTVRMKKGESVIGREVPLYLYCRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTLNEKQMWIGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKILMALEGDKKNKSSFGFNPEGLLEKIEECLINNPMCLFMAQRLNELVIEASKRGAKFFKT 6f5p A 4.14 BS03 MG A 1 H41 D93 E104 K119 H41 D93 E104 K119 3.1.-.- Q9IMP5 29910112 MSKTFAEIAEAFLEPEAVRIAKEAVEEYGDHERKIIQIGIHFQVCCMFCDEYLSTNGSDRFVLIEGRKRGTAVSLQNELCKSYDLEPLPFLCDIFDREEKQFVEIGITRKADDSYFQSKFGKLGNSCKIFVFSYDGRLDKNCEGPMEEQKLRIFSFLATAADFLRKENMFNEIFLPDNEETIIEMKKGKTFLELRDESVPLPFQTYEQMKDYCEKFKGNPRELASKVSQMQSNIKLPIKHYEQNKFRQIRLPKGPMAPYTHKFLMEEAWMFTKISDPERSRAGEILIDFFKKGNLSAIRPKDKPLQGKYPIHYKNLWNQIKAAIADRTMVINENDHSEFLGGIGRASKKIPEISLTQDVITTEGLKQSENKLPEPRSFPRWFNAEWMWAIKDSDLTGWVPMAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVGALMTECRLFPGKIKVVPIYARSKERKSMQEGLPVPSEMDCLFGICVKSKSHLNKDDGMYTIITFEFSIREPNLEKHQKYTVFEAGHTTVRMKKGESVIGREVPLYLYCRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTLNEKQMWIGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKILMALEGDKKNKSSFGFNPEGLLEKIEECLINNPMCLFMAQRLNELVIEASKRGAKFFKT 6f5p A 4.14 BS04 MG A 2 E65 L91 D93 E104 E65 L91 D93 E104 3.1.-.- Q9IMP5 29910112 MSKTFAEIAEAFLEPEAVRIAKEAVEEYGDHERKIIQIGIHFQVCCMFCDEYLSTNGSDRFVLIEGRKRGTAVSLQNELCKSYDLEPLPFLCDIFDREEKQFVEIGITRKADDSYFQSKFGKLGNSCKIFVFSYDGRLDKNCEGPMEEQKLRIFSFLATAADFLRKENMFNEIFLPDNEETIIEMKKGKTFLELRDESVPLPFQTYEQMKDYCEKFKGNPRELASKVSQMQSNIKLPIKHYEQNKFRQIRLPKGPMAPYTHKFLMEEAWMFTKISDPERSRAGEILIDFFKKGNLSAIRPKDKPLQGKYPIHYKNLWNQIKAAIADRTMVINENDHSEFLGGIGRASKKIPEISLTQDVITTEGLKQSENKLPEPRSFPRWFNAEWMWAIKDSDLTGWVPMAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVGALMTECRLFPGKIKVVPIYARSKERKSMQEGLPVPSEMDCLFGICVKSKSHLNKDDGMYTIITFEFSIREPNLEKHQKYTVFEAGHTTVRMKKGESVIGREVPLYLYCRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTLNEKQMWIGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKILMALEGDKKNKSSFGFNPEGLLEKIEECLINNPMCLFMAQRLNELVIEASKRGAKFFKT 6f5p B 4.14 BS01 III G 1 W457 R465 W435 R443 2.7.7.48 Q9IMP4 29910112 MEINPYLMFLNNDVTSLISTTYPYTGPPPMSHGSSTKYTLETIKRTYDYSRTSVEKTSKVFNIPRRKFCNCLEDKDELVKPTGNVDISSLLGLAEMMEKRMGEGFFKHCVMEAETEILKMHFSRLTEGRQTYDWTSERNMPAATALQLTVDAIKETEGPFKGTTMLEYCNKMIEMLDWKEIKFKKVKTVVRKTKVPVMGIDSIKHDEFLIRALTINTMAAIATPGMIVRPFSKIVETVAQKICEKLKESGLPVGGNEKKAKLKTTVTSLNARMNSDQFAVNITGDNSKWNECQQPEAYLALLAYITKDSSDLMKDLCSVAPVLFCNKFVKLGQGIRLSNKRKTKEVIIKAEKMGKYKNLMREEYKNLFEPLEKYIQKDVCFLPGGMLMGMFNMLSTVLGVSTLCYMDEELKAKGCFWTGLQSSDDFVLFAVASNWSNIHWTIRRFNAVCKLIGINMSLEKSYGSLPELFEFTSMFFDGEFVSNLAMELPAFTTAGVNEGVDFTAAMSIIKTNMINNSLSPSTALMALRICLQEFRATYRVHPWDSRVKGGRMKIINEFIKTIENKDGLLIADGGKLMNNISTLHIPEEVLKFEKMDEQYRNRVFNPKNPFEAVVSTHSFRTRANRTLLNTDMRAMMAEEKRYQMVCDMFKSVFESADINPPIGAMSIGEAIEEKLLERAKMKRDIGAIEDSEYEEIKDIIRDAKKARLES 6f7l A 2.50 BS01 FAD A 1 G14 G16 G17 S18 F35 E36 A37 G43 H44 G62 V63 E64 H65 P227 V228 T256 H257 V260 L264 F345 W362 L364 G391 T392 G398 H399 A402 G12 G14 G15 S16 F33 E34 A35 G41 H42 G60 V61 E62 H63 P220 V221 T249 H250 V253 L257 F338 W355 L357 G384 T385 G391 H392 A395 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7l A 2.50 BS02 CA A 1 N162 E318 Q320 N155 E311 Q313 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7l A 2.50 BS03 CWH A 1 G62 E64 L70 I167 Y168 N179 M181 Y182 L185 W200 Q326 F345 V372 V396 T397 G398 G60 E62 L68 I160 Y161 N172 M174 Y175 L178 W193 Q319 F338 V365 V389 T390 G391 Q83X90 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7l B 2.50 BS01 FAD B 1 G14 G16 G17 S18 F35 E36 A37 G42 G43 H44 G62 V63 E64 H65 P227 V228 T256 H257 L264 W362 L364 G391 T392 G398 H399 A402 G11 G13 G14 S15 F32 E33 A34 G39 G40 H41 G59 V60 E61 H62 P217 V218 T246 H247 L254 W352 L354 G381 T382 G388 H389 A392 Q83X90 VEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7l B 2.50 BS02 CA B 1 K336 V337 K326 V327 Q83X90 VEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7l B 2.50 BS03 CWH B 1 E64 H65 L70 I167 Y168 N179 M181 Y182 L185 W200 Q326 V396 T397 Q428 E61 H62 L67 I157 Y158 N169 M171 Y172 L175 W190 Q316 V386 T387 Q418 Q83X90 VEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7v A 3.03 BS01 FAD A 1 G14 G16 G17 S18 F35 E36 A37 G43 H44 G62 V63 Q64 H65 P227 V228 A255 T256 H257 V260 W362 L364 G391 T392 G398 H399 A402 G11 G13 G14 S15 F32 E33 A34 G40 H41 G59 V60 Q61 H62 P219 V220 A247 T248 H249 V252 W354 L356 G383 T384 G390 H391 A394 1.4.3.4 G4V2H3 VEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVQHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7v A 3.03 BS03 CWH A 1 Q64 L70 S166 I167 Y168 G170 N179 M181 Y182 L324 R326 F345 V372 V396 T397 G398 Q428 Q61 L67 S158 I159 Y160 G162 N171 M173 Y174 L316 R318 F337 V364 V388 T389 G390 Q420 1.4.3.4 G4V2H3 VEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVQHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6f7v B 3.03 BS02 CWH B 1 Q64 L70 S166 I167 Y168 G170 N179 M181 Y182 R326 F345 V396 T397 G398 Q428 Q62 L68 S159 I160 Y161 G163 N172 M174 Y175 R319 F338 V389 T390 G391 Q421 1.4.3.4 G4V2H3 VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVQHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6fjh A 3.15 BS02 OXY A 1 Y168 T397 Y160 T389 G4V2H3 VEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVETDQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQSWNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFKYKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGIHSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATHADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFRMPEGFELARAEEQMGSLTRNCNVLHPYRKVSSPILITFDPQEDVDPERVIVRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGMVIADRLGVPHPFPDDAPAAAQFRGIKEFMGV 6g04 A BS01 III B 1 A34 R35 E37 L38 S41 M42 Y45 D62 E65 K66 D68 W69 T71 G72 I73 V75 L88 E91 T92 Y95 D99 E100 E133 Y136 W139 A34 R35 E37 L38 S41 M42 Y45 D62 E65 K66 D68 W69 T71 G72 I73 V75 L88 E91 T92 Y95 D99 E100 E133 Y136 W139 Q06672 30201955 SGSHMSTQYIDETAFVQAEQGKTNLMFSDEKQQARFELGVSMVIYKWDALDVAVENSWGGPDSAEKRDWITGIVVDLFKNEKVVDAALIEETLLYAMIDEFETNVEDDSALPIAVEVINIYNDCFNLNYNKVEKLYLEWQEKQRTKKSKRVVHIEG 6gbx A 1.72 BS02 S77 A 1 K144 D159 E201 E202 W207 D248 Q304 D305 I321 F325 W329 H330 K111 D126 E168 E169 W174 D215 Q271 D272 I288 F292 W296 H297 2.3.2.5 Q16769 30132075 SAWPEEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPEGERSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLSLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHGMDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLHL 6gcd A 1.80 BS02 NUC D 1 S38 G40 Y41 N43 F44 T45 W49 A59 S60 Y64 V66 I82 S83 D84 T85 K116 Y117 S38 G40 Y41 N43 F44 T45 W49 A59 S60 Y64 V66 I82 S83 D84 T85 K116 Y117 3.1.21.- P15005 30194838 MESIQPWIEKFIKQAQQQRSQSTKDYPTSYRNLRVKLSFGYGNFTSIPWFAFLGEGQEASNGIYPVILYYKDFDELVLAYGISDTNEPHAQWQFSSDIPKTIAEYFQATSGVYPKKYGQSYYACSQKVSQGIDYTRFASMLDNIINDYKLIFNSGKSVI 6gcd B 1.80 BS02 NUC D 1 Q21 S22 T23 K24 Y41 G42 N43 Q21 S22 T23 K24 Y41 G42 N43 3.1.21.- P15005 30194838 MESIQPWIEKFIKQAQQQRSQSTKDYPTSYRNLRVKLSFGYGNFTSIPWFAFLGEGQEASNGIYPVILYYKDFDELVLAYGISDTNEPHAQWQFSSDIPKTIAEYFQATSGVYPKKYGQSYYACSQKVSQGIDYTRFASMLDNIINDYKLIFN 6gce A 1.60 BS01 NUC D 1 K36 S38 G40 Y41 N43 F44 T45 S46 W49 A59 S60 Y64 I82 S83 D84 T85 K116 Y117 K36 S38 G40 Y41 N43 F44 T45 S46 W49 A59 S60 Y64 I82 S83 D84 T85 K116 Y117 3.1.21.- P15005 30194838 MESIQPWIEKFIKQAQQQRSQSTKDYPTSYRNLRVKLSFGYGNFTSIPWFAFLGEGQEASNGIYPVILYYKDFDELVLAYGISDTNEPHAQWQFSSDIPKTIAEYFQATSGVYPKKYGQSYYACSQKVSQGIDYTRFASMLDNIINDYKLIFNSGKSV 6gcv A 1.30 BS01 NO3 A 1 G25 A26 R28 M29 G12 A13 R15 M16 A0A069QEB8 MSISPETINVAGAQRMLSQKMAREALQLRLGAGDPKALAATIAQYERSAADLDAGNAERNVSRMGAPEIAAQRQKVAQIWGRYRAMLDQVAQPASQVDLRGFSQYSTELLGELNNLVSLMSARADS 6gek A 2.28 BS01 III L 1 F337 Y369 N372 F373 K376 L377 M385 V389 F105 Y137 N140 F141 K144 L145 M153 V157 Q15561 30058229 RSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIFRLVKE 6gek A 2.28 BS02 III L 2 E263 V265 Q269 D272 K273 L295 K297 W299 E391 V414 Q425 H427 F429 E37 V39 Q43 D46 K47 L69 K71 W73 E159 V182 Q193 H195 F197 Q15561 30058229 RSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIFRLVKE 6gek B 2.28 BS01 III M 1 S336 F337 Y369 N372 F373 K376 L377 L380 V389 S113 F114 Y146 N149 F150 K153 L154 L157 V166 Q15561 30058229 RSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSAHGAQHHIFRLVKE 6gek B 2.28 BS02 III M 2 E263 V265 Q269 D272 K273 L295 K297 W299 E391 V414 E416 Q425 H426 H427 F429 E44 V46 Q50 D53 K54 L76 K78 W80 E168 V191 E193 Q200 H201 H202 F204 Q15561 30058229 RSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSAHGAQHHIFRLVKE 6gfk A 2.30 BS01 SAH A 1 L75 R82 G110 T111 G112 Y117 T132 E133 V134 D135 C138 T164 L165 N184 P186 F188 L35 R42 G70 T71 G72 Y77 T92 E93 V94 D95 C98 T124 L125 N144 P146 F148 2.1.1.346,2.1.1.62 Q86W50 30197299 RVSLNFKDPEAVRALTCTLLREDFGLSIDIPLERLIPTVPLRLNYIHWVEDLIGHQDSDKSTLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSDLIKVVKVPQKTLLMDALKEESEIIYDFCMCNPPFFANQGGITEIMAEGGELEFVKRIIHDSLQLKKRLRWYSCMLGKKCSLAPLKEELRIQGVPKVTYTEFCQGRTMRWALAWSFYD 6gfn A 2.86 BS01 SAH A 1 R82 G110 T111 G112 S114 I116 Y117 T132 E133 V134 D135 C138 V160 Q162 T164 L165 N184 P186 R230 R82 G108 T109 G110 S112 I114 Y115 T130 E131 V132 D133 C136 V158 Q160 T162 L163 N182 P184 R193 2.1.1.346,2.1.1.62 Q86W50 30197299 MALSKSMHARNRYKDKPPDFAYLASKYPDFKQHVQINLNGRVSLNFKDPEAVRALTCTLLREDFGLSIDIPLERLIPTVPLRLNYIHWVEDLIGHQDKSTLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSDLIKVVKVPQKTLLMDALKEESEIIYDFCMCNPPFGELEFVKRIIHDSLQLKKRLRWYSCMLGKKCSLAPLKEELRIQGVPKVTYTEFCQGRTMRWALAWSFYD 6gg2 A 2.60 BS01 FAD A 1 G11 G13 V14 F15 D38 R39 N53 A57 N58 R63 V64 G209 E210 V211 A243 G244 R246 I250 V264 C414 W415 Y416 G442 D444 H445 A446 F447 K448 G10 G12 V13 F14 D37 R38 N52 A56 N57 R62 V63 G208 E209 V210 A242 G243 R245 I249 V263 C413 W414 Y415 G441 D443 H444 A445 F446 K447 1.5.3.- Q4WD43 30194285 SIPNSFIIVGSGVFGLSLAYALSLDDRFADKKIILVDRWNFEPPNATGSVHNPAAANADTSRVIRRDYPHGPYASLALEAMKHWRGKFGENNRYVNQRLLFSGEGSSLTTPPKALETVNYIKKAYAISCELTPGGRDAVQVLDSLDEVRAFLGNTPSHPPHLPVNKDPAARDLRGYVSNDCGWADAGASIEWLRQEVLRLGRVECVVGEVESLVYSDDQRAVKGVKLVDGKVLTAELTVIAAGARSSHILGIPKLCDVYSEFVAYIQLTKEEADELRRRQWPILVNCHRGVFAVGPDHDNCLKFGHFSYSGIVDVLREASIQVPTRPDGWEAQQKYWSDPRFAFGGEVKVSALGDVDDYENPAAQRALADYRLFLLELLGPTGLQGVDTLGLDQSDNLLNNIANRPFTRVRKCWYNDTPALDFVVDYHPSYGKTLFVATGGCDHAFKFLPIIGEKTLALILRNRGDSAVSLPAGVEPSLEELSELWRFPVELLQ 6ghj A 2.26 BS01 III B 1 R26 Y30 Y68 K126 I155 A159 W296 E299 N328 P329 I332 E400 S431 R22 Y26 Y64 K122 I151 A155 W285 E288 N317 P318 I321 E385 S410 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS06 78N A 3 F319 W323 F324 S326 L330 P386 V390 F308 W312 F313 S315 L319 P371 V375 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS07 78N A 4 M96 S180 A183 I184 M92 S176 A179 I180 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS08 78N A 5 I59 I62 M66 F112 I115 I116 L246 L253 I55 I58 M62 F108 I111 I112 L242 L249 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS09 78N A 6 F112 F231 I232 N244 L246 Y249 F108 F227 I228 N240 L242 Y245 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS10 78N A 7 I234 M238 W243 A248 N251 L252 I255 V256 A259 I260 F263 I230 M234 W239 A244 N247 L248 I251 V252 A255 I256 F259 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS11 78N A 8 P86 F89 W90 Y194 L206 P82 F85 W86 Y190 L202 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS12 78N A 9 I81 L212 V224 I77 L208 V220 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6ghj A 2.26 BS14 78M A 3 L294 L444 A452 Y456 F457 L283 L423 A431 Y435 F436 Q5M4H8 30194725 GKTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISSHLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTKLSQMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLSKRIQGL 6gjg A 1.99 BS02 F1T A 1 L172 L176 G181 C184 H185 F188 F227 I263 R265 Y528 L531 V532 M536 L11 L15 G20 C23 H24 F27 F66 I102 R104 Y332 L335 V336 M340 1.3.5.2 Q08210 30197997 NPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKHIVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHS 6gqj A 2.33 BS01 F82 A 1 L595 V603 A621 K623 E640 L644 L647 I653 V668 T670 E671 Y672 C673 G676 H790 L799 I808 C809 D810 F811 L29 V37 A55 K57 E74 L78 L81 I87 V102 T104 E105 Y106 C107 G110 H157 L166 I175 C176 D177 F178 2.7.10.1 P10721 30204441 NYSYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKSDAAMTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTHGGPTLVITEYCCYGDLLNFLRRKRDEFVPYKKDFLTLEHLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGNITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEYAPAEMYDIMKTCWDADPDKRPTFKQIVQDIEKQISES 6gqj B 2.33 BS01 F82 B 1 L595 V603 A621 K623 E640 L644 L647 I653 V668 T670 E671 Y672 C673 C674 G676 L783 H790 L799 C809 D810 F811 L24 V32 A50 K52 E69 L73 L76 I82 V97 T99 E100 Y101 C102 C103 G105 L144 H151 L160 C170 D171 F172 2.7.10.1 P10721 30204441 DPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKSDAAMTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTHGGPTLVITEYCCYGDLLNFLRRKRDEFVPYKDFLTLEHLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGNITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEYAPAEMYDIMKTCWDADPDKRPTFKQIVQDIEKQISES 6gqk A 2.31 BS01 F88 A 1 L595 V603 A621 K623 E640 L644 I653 T670 E671 Y672 C673 G676 L799 I808 C809 D810 F811 L29 V37 A55 K57 E74 L78 I87 T104 E105 Y106 C107 G110 L173 I182 C183 D184 F185 2.7.10.1,2.7.10.1 P10721 30204441 NYSYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKSDAAMTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTHGGPTLVITEYCCYGDLLNFLRRKRDEFVPYKVAPEDLYKDFLTLEHLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGNITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEYAPAEMYDIMKTCWDADPDKRPTFKQIVQDIEKQISES 6gql A 2.01 BS01 F8B A 1 L595 V603 A621 E640 L644 L647 V654 T670 E671 Y672 C673 G676 L799 I808 C809 D810 F811 L28 V36 A54 E73 L77 L80 V87 T103 E104 Y105 C106 G109 L166 I175 C176 D177 F178 2.7.10.1 P10721 30204441 YSYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKSDAAMTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTHGGPTLVITEYCCYGDLLNFLRRKRDEFVPYLYKDFLTLEHLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGNITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEYAPAEMYDIMKTCWDADPDKRPTFKQIVQDIEKQISES 6gqo A 1.87 BS01 F82 A 1 L840 V848 A866 V867 K868 E885 L889 I892 V898 V899 V914 V916 E917 F918 C919 K920 G922 L1019 H1026 L1035 C1045 D1046 F1047 L30 V38 A56 V57 K58 E75 L79 I82 V88 V89 V104 V106 E107 F108 C109 K110 G112 L159 H166 L175 C185 D186 F187 2.7.10.1 P35968 30204441 LPLDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA 6gqp A 2.09 BS01 F88 A 1 L840 V848 A866 K868 E885 L889 V898 V899 V916 E917 C919 H1026 L1035 I1044 C1045 D1046 L20 V28 A46 K48 E65 L69 V78 V79 V96 E97 C99 H156 L165 I174 C175 D176 2.7.10.1 P35968 30204441 PYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA 6gqq A 1.52 BS01 F8B A 1 L840 V848 A866 K868 E885 L889 I892 V916 E917 C919 K920 L1035 I1044 C1045 D1046 F1047 L28 V36 A54 K56 E73 L77 I80 V104 E105 C107 K108 L173 I182 C183 D184 F185 2.7.10.1 P35968 30204441 LDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQAN 6grv A BS01 CD A 1 C7 C10 C32 H36 C49 C7 C10 C32 H36 C49 J2EKT7 30191219 NELRCGCPDCHCKVDPERVFNHDGEAYCSQACAEQHPNGEPCPAPDCHCERSGKVGGRDITNNQLDEALEETFPASDPISP 6grv A BS02 CD A 2 C10 C42 C47 C49 C10 C42 C47 C49 J2EKT7 30191219 NELRCGCPDCHCKVDPERVFNHDGEAYCSQACAEQHPNGEPCPAPDCHCERSGKVGGRDITNNQLDEALEETFPASDPISP 6gsg A 2.19 BS03 RCO A 1 H110 H284 H288 Y289 G296 V299 S302 H98 H272 H276 Y277 G284 V287 S290 Q2UNF9 30204291 TLPTTASSSTAVASSQLDQLANFAYNVTTDSVAGCTLQNLRVRRDWRAFSKTQKKDYINSVLCLQKLPSRTPAHLAPGARTRYDDFVATHINQTQIIHYTGTFLAWHRYFIYEFEQALRDECSYTGDYPYWNWGADADNMEKSQVFDGSETSMSGNGEYIPNQGDIKLLLGNYPAIDLPPGSGGGCVTSGPFKDYKLNLGPAALSLPGGNMTAAANPLTYNPRCMKRSLTTEILQRYNTFPKIVELILDSDDIWDFQMTMQGVPGSGSIGVHGGGHYSMGGDPGRDVYVSPGDTAFWLHHGMIDRVWWIWQNLDLRKRQNAISGTGTFMNNPASPNTTLDTVIDLGYANGGPIAMRDLMSTTAGPFCYVYL 6gv6 A BS01 CD A 1 C7 C32 H36 C49 C7 C32 H36 C49 J2EKT7 30191219 NELRCGCPDCHCKVDPERVFNHDGEAYCSQACAEQHPNGEPCPAPDCHCERS 6gv7 A BS03 CD A 3 C12 C28 C42 H44 C12 C28 C42 H44 J2EKT7 30191219 NELRCGCPDCHCKVDPERVFNHDGEAYCSQACAEQHPNGEPCPHPDCHCERS 6h3k A 2.48 BS01 FMW A 1 I531 Q541 A551 I586 M602 E603 C604 G605 N606 I607 D608 S611 A651 L654 I663 P673 I16 Q26 A36 I71 M87 E88 C89 G90 N91 I92 D93 S96 A136 L139 I148 P158 2.7.12.1 P33981 30199249 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPTVNYMPPEAIKDMSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 6h3k A 2.48 BS02 7PE A 1 H636 H639 P713 K714 S781 I782 P783 H121 H124 P176 K177 S244 I245 P246 2.7.12.1 P33981 30199249 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPTVNYMPPEAIKDMSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 6hfv A 2.05 BS02 G1Z A 1 G117 G133 K134 L317 Q336 V365 K367 N385 C387 K418 G109 G125 K126 L294 Q302 V331 K333 N351 C353 K384 1.1.98.3 P9WJF1 30194385 TTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGRGAIARGLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTADGEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQLPAKLRSEPLKFDANKYTFGPIGELWYRKSGTYRGKVQNLTQFYHPLDMGFLQYQFVIPTEAVDEFKKIIGVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLELL 6hfv B 2.05 BS02 G1Z B 1 G117 H132 G133 K134 L317 Q336 V365 K367 N385 C387 K418 G109 H124 G125 K126 L285 Q291 V320 K322 N340 C342 K373 1.1.98.3 P9WJF1 30194385 TTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGRGAIARGLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTADGEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQLPAKLRSEPLKFDGELWYRKSGTYRGKVQNLTQFYHPLGFLQYQFVIPTEAVDEFKKIIGVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLELL 6hij A 3.56 BS01 CLR A 1 F571 Y576 C635 I639 F489 Y494 C553 I557 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij A 3.56 BS02 CLR A 2 M523 F547 M548 F551 L568 F571 F640 K647 M441 F465 M466 F469 L486 F489 F558 K565 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij A 3.56 BS03 CLR A 3 S467 L471 A634 L641 T642 Y645 S385 L389 A552 L559 T560 Y563 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij A 3.56 BS04 CLR A 4 F507 M510 M514 W627 F425 M428 M432 W545 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij A 3.56 BS05 CLR A 5 R378 S381 F385 L475 L479 M483 L484 R296 S299 F303 L393 L397 M401 L402 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij B 3.56 BS02 CLR B 1 F571 Y576 A632 C635 I639 F489 Y494 A550 C553 I557 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij B 3.56 BS04 CLR B 3 S467 L471 A634 T642 Y645 S385 L389 A552 T560 Y563 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij B 3.56 BS05 CLR B 4 D504 F507 M510 M514 W627 D422 F425 M428 M432 W545 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6hij B 3.56 BS06 CLR B 5 S381 F385 L475 P480 M483 L484 S299 F303 L393 P398 M401 L402 Q9UNQ0 GAVLSFHNICYRVKLPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDLIEKLAEIYVNSSFYKETKAELHQLSGYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKY 6mbf A 1.54 BS01 MG A 1 L1744 G1745 P1920 L43 G44 P214 U6BSB2 30179448 FHPLLGRRVPDPAPGARCFTGTVSSDRPAYLGEHWVYDAIVVLGVTYLEMALAAASRLLPGNAADTLIVEDVTVWSPLVLRAGAPARLRLRSEDERFEIHSAEPERSDDESAWTRHATGRIARRQLGQLPRLDGEAVELDAYYERMRIYYGPRLRNIRHLERRGREAIGHVCLQGEEAQESASYELHPALLDACFQCVFALIYAHESHREPFVPLGCARIELRARGVREVRVHLRLHPPRSTDHNQTHTADLRLFDMEGRLVASVDALQLKRAS 6mdm A 4.40 BS01 ATP A 1 M504 N505 G506 I507 I508 W510 V514 P545 H546 G548 T550 A551 D604 I707 K708 L711 M465 N466 G467 I468 I469 W471 V475 P506 H507 G509 T511 A512 D565 I668 K669 L672 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm A 4.40 BS02 ADP A 1 G219 I220 G221 P262 C264 G265 T267 L268 M372 I406 H410 G438 A439 E442 G197 I198 G199 P240 C242 G243 T245 L246 M350 I384 H388 G416 A417 E420 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm A 4.40 BS03 ATP B 1 L355 D359 R385 R388 L333 D337 R363 R366 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm B 4.40 BS01 ATP B 1 G219 I220 G221 P261 P262 C264 G265 K266 T267 L268 N374 I406 I409 H410 G438 A439 E442 G199 I200 G201 P241 P242 C244 G245 K246 T247 L248 N354 I386 I389 H390 G418 A419 E422 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIASVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm B 4.40 BS02 ATP B 2 I503 M504 N505 G506 I507 I508 W510 V514 P545 G548 K549 T550 A551 L552 D604 K708 I469 M470 N471 G472 I473 I474 W476 V480 P511 G514 K515 T516 A517 L518 D570 K674 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIASVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm B 4.40 BS03 ATP C 1 K251 D359 R385 R388 K231 D339 R365 R368 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIASVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm C 4.40 BS01 ATP C 2 Y502 I503 M504 N505 G506 I507 I508 W510 V514 P545 H546 S547 G548 K549 T550 A551 L552 I707 K708 Y473 I474 M475 N476 G477 I478 I479 W481 V485 P516 H517 S518 G519 K520 T521 A522 L523 I678 K679 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm C 4.40 BS02 ATP C 1 G219 I220 G221 L223 P262 G263 C264 G265 K266 T267 L268 E329 I406 H410 A439 E442 G200 I201 G202 L204 P243 G244 C245 G246 K247 T248 L249 E310 I387 H391 A420 E423 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm C 4.40 BS03 ATP D 1 D359 R385 R388 D340 R366 R369 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm D 4.40 BS01 ATP D 2 M504 N505 G506 I507 I508 W510 V514 P545 H546 S547 G548 T550 A551 L552 I707 K708 M479 N480 G481 I482 I483 W485 V489 P520 H521 S522 G523 T525 A526 L527 I682 K683 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm D 4.40 BS02 ATP D 1 I220 G222 P262 G263 C264 G265 K266 T267 L268 R271 E329 N374 I406 H410 G438 A439 E442 I201 G203 P243 G244 C245 G246 K247 T248 L249 R252 E310 N355 I387 H391 G419 A420 E423 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm D 4.40 BS03 ADP E 1 K251 D359 A382 R385 R388 K232 D340 A363 R366 R369 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm E 4.40 BS01 ATP E 1 M504 N505 G506 I507 I508 W510 V514 P545 H546 G548 K549 T550 A551 L552 D604 I707 K708 M280 N281 G282 I283 I284 W286 V290 P321 H322 G324 K325 T326 A327 L328 D380 I483 K484 3.6.4.6 P18708 NPDWNFEKMGIGGLDKEFSDIFRRAFASRVFCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm E 4.40 BS02 ADP E 1 I220 G221 P262 G263 C264 G265 K266 T267 L268 N374 I406 I409 H410 A439 I11 G12 P44 G45 C46 G47 K48 T49 L50 N156 I188 I191 H192 A221 3.6.4.6 P18708 NPDWNFEKMGIGGLDKEFSDIFRRAFASRVFCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdm F 4.40 BS01 ATP F 1 M504 N505 I507 I508 W510 V514 P545 H546 S547 G548 K549 T550 D604 I707 K708 M232 N233 I235 I236 W238 V242 P273 H274 S275 G276 K277 T278 D332 I435 K436 3.6.4.6 P18708 GIGGLDKEFSDIFRRAFASRVKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEPDEKGRLQILHIHTARMADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn A 4.40 BS01 ATP A 1 M504 N505 G506 I507 I508 K509 W510 V514 P545 H546 S547 G548 T550 D604 I707 K708 M277 N278 G279 I280 I281 K282 W283 V287 P318 H319 S320 G321 T323 D377 I480 K481 3.6.4.6 P18708 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn A 4.40 BS02 ADP A 1 G219 I220 G221 P262 G263 C264 G265 T267 L268 I406 G438 A439 E442 G9 I10 G11 P52 G53 C54 G55 T57 L58 I196 G228 A229 E232 3.6.4.6 P18708 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn B 4.40 BS01 ATP B 1 I220 G221 P261 P262 C264 G265 K266 T267 L268 E329 I406 H410 G438 A439 E442 I203 G204 P244 P245 C247 G248 K249 T250 L251 E312 I389 H393 G421 A422 E425 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIASVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn B 4.40 BS02 ATP B 2 M504 N505 G506 I507 I508 W510 V514 P545 G548 K549 T550 A551 L552 I707 K708 M473 N474 G475 I476 I477 W479 V483 P514 G517 K518 T519 A520 L521 I676 K677 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIASVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn C 4.40 BS01 ATP C 2 Y502 M504 N505 G506 I507 I508 W510 V514 P545 H546 S547 G548 K549 T550 L552 I707 K708 Y473 M475 N476 G477 I478 I479 W481 V485 P516 H517 S518 G519 K520 T521 L523 I678 K679 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn D 4.40 BS02 ATP D 1 I220 P262 G263 C264 G265 K266 T267 L268 R271 N374 I406 H410 G438 A439 E442 I201 P243 G244 C245 G246 K247 T248 L249 R252 N355 I387 H391 G419 A420 E423 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn D 4.40 BS03 ADP E 1 K251 R385 R388 K232 R366 R369 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdn E 4.40 BS02 ADP E 1 I220 G221 G222 P262 G263 C264 G265 K266 T267 L268 N374 I406 I409 H410 G438 A439 E442 I194 G195 G196 P227 G228 C229 G230 K231 T232 L233 N339 I371 I374 H375 G403 A404 E407 3.6.4.6 P18708 MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTFEKMGIGGLDKEFSDIFRRAFASRVFCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo A 3.90 BS01 III H 1 K293 Y294 V346 H347 K83 Y84 V136 H137 3.6.4.6 P18708 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo A 3.90 BS03 ADP A 1 G219 I220 G221 P262 C264 G265 K266 T267 L268 I406 I409 H410 G438 A439 E442 G9 I10 G11 P52 C54 G55 K56 T57 L58 I196 I199 H200 G228 A229 E232 3.6.4.6 P18708 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIARGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo C 3.90 BS01 III H 1 K293 Y294 V295 V346 K86 Y87 V88 V139 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo C 3.90 BS02 ATP C 2 Y502 M504 N505 G506 I507 I508 W510 V514 H546 G548 K549 T550 L552 I707 K708 Y285 M287 N288 G289 I290 I291 W293 V297 H329 G331 K332 T333 L335 I490 K491 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo C 3.90 BS03 ATP C 1 G219 I220 G221 P261 P262 G263 C264 G265 K266 T267 L268 N374 I406 H410 S437 A439 E442 G12 I13 G14 P54 P55 G56 C57 G58 K59 T60 L61 N167 I199 H203 S230 A232 E235 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo D 3.90 BS01 III H 1 K293 Y294 S343 T344 H347 K86 Y87 S136 T137 H140 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo D 3.90 BS02 ATP D 2 I503 M504 N505 G506 I507 I508 W510 V514 H546 S547 G548 K549 T550 A551 L552 D604 I707 K708 I290 M291 N292 G293 I294 I295 W297 V301 H333 S334 G335 K336 T337 A338 L339 D391 I494 K495 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo D 3.90 BS04 ADP E 1 K251 Q363 R385 R388 K44 Q156 R178 R181 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo E 3.90 BS01 III H 1 K293 Y294 V295 S343 T344 K70 Y71 V72 S120 T121 3.6.4.6 P18708 FEKMGIGGLDKEFSDIFRRAFASRVFCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo E 3.90 BS03 ADP E 1 I220 G221 G222 P262 G263 C264 G265 K266 T267 L268 N374 I406 I409 H410 G438 I6 G7 G8 P39 G40 C41 G42 K43 T44 L45 N151 I183 I186 H187 G215 3.6.4.6 P18708 FEKMGIGGLDKEFSDIFRRAFASRVFCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdo F 3.90 BS01 ATP F 1 M504 N505 I507 I508 W510 V514 S547 G548 K549 T550 D604 I707 K708 M7 N8 I10 I11 W13 V17 S50 G51 K52 T53 D107 I210 K211 3.6.4.6 P18708 DYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp A 3.80 BS02 ADP A 1 G221 L223 P262 C264 G265 K266 T267 L268 I406 A439 G11 L13 P52 C54 G55 K56 T57 L58 I196 A229 3.6.4.6 P18708 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIITRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp B 3.80 BS01 III H 1 K293 Y294 V295 A341 V346 K87 Y88 V89 A135 V140 3.6.4.6 P18708 SIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp B 3.80 BS02 ATP B 2 Y502 M504 N505 G506 I508 W510 V514 H546 S547 G548 K549 T550 A551 L552 I707 Y280 M282 N283 G284 I286 W288 V292 H324 S325 G326 K327 T328 A329 L330 I485 3.6.4.6 P18708 SIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp B 3.80 BS03 ATP B 1 I220 G221 P262 G263 G265 K266 T267 L268 E329 N374 I406 G438 A439 E442 I14 G15 P56 G57 G59 K60 T61 L62 E123 N168 I200 G232 A233 E236 3.6.4.6 P18708 SIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp B 3.80 BS04 ATP C 1 K251 L355 D359 R385 R388 K45 L149 D153 R179 R182 3.6.4.6 P18708 SIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp C 3.80 BS01 III H 1 K293 Y294 V295 G342 S343 V346 K86 Y87 V88 G135 S136 V139 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp C 3.80 BS03 ATP C 1 I220 G221 L223 P262 G263 C264 G265 K266 T267 L268 E329 N374 I406 G438 A439 I13 G14 L16 P55 G56 C57 G58 K59 T60 L61 E122 N167 I199 G231 A232 3.6.4.6 P18708 IINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp D 3.80 BS01 III H 1 K293 Y294 V295 K85 Y86 V87 3.6.4.6 P18708 INPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIAEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp D 3.80 BS02 ATP D 2 I503 M504 N505 G506 I507 I508 W510 V514 P545 H546 G548 K549 A551 L552 I707 K708 I291 M292 N293 G294 I295 I296 W298 V302 P333 H334 G336 K337 A339 L340 I495 K496 3.6.4.6 P18708 INPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIAEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp D 3.80 BS03 ATP D 1 G219 I220 G221 P262 G263 C264 G265 K266 T267 L268 E329 M372 N374 I406 G438 A439 E442 G11 I12 G13 P54 G55 C56 G57 K58 T59 L60 E121 M164 N166 I198 G230 A231 E234 3.6.4.6 P18708 INPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIAEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp D 3.80 BS04 ADP E 1 K251 R388 K43 R180 3.6.4.6 P18708 INPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIIAEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp E 3.80 BS01 III H 1 K293 Y294 V295 G342 T344 G345 H347 D348 K62 Y63 V64 G111 T113 G114 H116 D117 3.6.4.6 P18708 EKMGIGGLDKEFSDIFRRAFHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHILQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp E 3.80 BS03 ADP E 1 G219 I220 G222 P262 G263 C264 G265 K266 T267 L268 I406 H410 G438 A439 R446 G4 I5 G7 P31 G32 C33 G34 K35 T36 L37 I175 H179 G207 A208 R215 3.6.4.6 P18708 EKMGIGGLDKEFSDIFRRAFHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHILQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA 6mdp F 3.80 BS01 ATP F 1 M504 N505 G506 I508 W510 V514 P545 G548 K549 T550 A551 L552 D604 S647 I707 K708 L711 M9 N10 G11 I13 W15 V19 P50 G53 K54 T55 A56 L57 D109 S152 I212 K213 L216 3.6.4.6 P18708 QEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGA