5mf7 A 1.59 BS01 NUC C 1 R248 R280 R143 R175 P04637 SSSVPSQKTYQGSYGFRLGFLVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKG 5n12 A 1.38 BS02 8FH A 1 K35 S39 F44 N55 V58 K12 S16 F21 N32 V35 3.4.24.89 Q183R7 29717999 SHMDSTTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK 5n12 B 1.38 BS03 8FH B 2 S39 Q40 V42 K78 S13 Q14 V16 K52 3.4.24.89 Q183R7 29717999 DSTTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK 5np9 A 2.00 BS01 ADP A 1 T8 N10 P11 T14 D36 L37 G38 A39 G40 K41 T42 T43 E106 D130 R132 T8 N10 P11 T14 D36 L37 G38 A39 G40 K41 T42 T43 E104 D128 R130 O05515 28890133 MKQLKWRTVNPEETKAIAKLTAAFAKPGDVLTLEGDLGAGKTTFTKGFAEGLGITRIVNSPTFTIIKEYNDGVLPLYHMDVYRMEDEDLGLDEYFHGQGVCLVEWAHLIEEQLPQERLQIVIKRAGDDEREITFTAVGNRYEMLCEELSRHD 5npl A 2.79 BS01 DO3 A 1 C153 E158 W167 C152 E157 W166 A8YJ50 PMVLQAQEIMTQNVVTIRGSATVADAVKLMKEKKLRGLIVEPRHEQDPYGIVTETDIVYKVAAFGHDPKTMRVYEIMAKPCVVVNPELGVEYVARLFAQTRIRRAPVIQGKTLLGIISVSDILFKSDFVEKPKRLFIEDEIEAAREDARAICAAKGETSPDCAAAWDVVEELQAEASHQRA 5npq A 2.37 BS01 94Q A 1 Y117 Q118 F119 W120 Y180 V181 I245 N246 F247 L248 C249 V250 R255 S256 K257 R258 V259 A260 P261 I264 I267 T268 V271 F277 A279 Y281 T282 L287 Y479 Y3 Q4 F5 W6 Y66 V67 I124 N125 F126 L127 C128 V129 R134 S135 K136 R137 V138 A139 P140 I143 I146 T147 V150 F156 A158 Y160 T161 L166 Y338 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 5npq B 2.37 BS01 94Q B 1 Y117 Q118 F119 W120 N179 Y180 V181 I245 N246 F247 L248 V250 R255 S256 K257 R258 V259 A260 P261 I264 I267 T268 V271 H272 F277 A279 Y281 T282 Y479 Y3 Q4 F5 W6 N65 Y66 V67 I131 N132 F133 L134 V136 R141 S142 K143 R144 V145 A146 P147 I150 I153 T154 V157 H158 F163 A165 Y167 T168 Y358 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 5npq B 2.37 BS02 MG B 1 L254 K257 R258 V259 L140 K143 R144 V145 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 5nqd A 2.20 BS01 MGD A 1 G174 H199 N200 K413 W417 H451 G486 C487 D488 T492 V543 D544 I545 I546 T548 A560 T562 D593 N718 R720 Q726 S727 Y729 F792 Q799 Y815 K816 G173 H198 N199 K412 W416 H450 G485 C486 D487 T491 V542 D543 I544 I545 T547 A559 T561 D592 N717 R719 Q725 S726 Y728 F791 Q798 Y814 K815 1.20.98.1 Q6VAL8 AFKRHIDRLPIIPADAKKHNVTCHFCIVGCGYHAYTWPINKQGGTDPQNNIFGVDLSEQQQAESDAWYSPSMYNVVKQDGRDVHVVIKPDHECVVNSGLGSVRGARMAETSFSEARNTQQQRLTDPLVWRYGQMQPTSWDDALDLVARVTAKIVKEKGEDALIVSAFDHGGAGGGYENTWGTGKLYFEAMKVKNIRIHNRPAYNSEVHGTRDMGVGELNNCYEDAELADTIVAVGTNALETQTNYFLNHWIPNLRGESLGKKKELMPEEPHEAGRIIIVDPRRTVTVNACEQTAGADNVLHLAINSGTDLALFNALFTYIADKGWVDRDFIDKSTLREGTARPPLYPARGVSEANPGHLSSFEDAVEGCRMSIEEAAEITGLDAAQIIKAAEWIGMPKEGGKRRRVMFGYEKGLIWGNDNYRTNGALVNLALATGNIGRPGGGVVRLGGHQEGYVRPSDAHVGRPAAYVDQLLIGGQGGVHHIWGCDHYKTTLNAHEFKRVYKKRTDMVKDAMSAAPYGDREAMVNAIVDAINQGGLFAVNVDIIPTKIGEACHVILPAATSGEMNLTSMNGERRMRLTERYMDPPGQSMPDCLIAARLANTMERVLTEMGDVGYAAQFKGFDWQTEEDAFMDGYNKNAHGGEFVTYERLSAMGTNGFQEPATGFTDGKIEGTQRLYTDGVFSTDDGKARFMDAPWRGLQAPGKQQQKDSHKYLINNGRANVVWQSAYLDQENDFVMDRFPYPFIEMNPEDMAEAGLKEGDLVEIYNDAGATQAMAYPTPTARRGETFMLFGFPTGVQGNVTSAGTNELIIPNYKQTWGNIRKISDAPRNVAHLSFKSKEYQS 5nqd D 2.20 BS01 FES D 1 C103 H105 K106 A108 C121 H124 S126 C60 H62 K63 A65 C78 H81 S83 1.20.98.1 L0NMC5 AAGVEYPANRLANISELTLNEPLDVAYPDEDAAGVLLKLGTRVEGGVGPDGDIVGFSTICPHKGAPLSYSADNKTFNCPGHFSVFDPEKGGQQVWGQATQNLPQYVLRVADNGDIFAEGVDELIYGRLSNVL 5nqd E 2.20 BS03 O E 1 H199 H451 H198 H450 1.20.98.1 Q6VAL8 AFKRHIDRLPIIPADAKKHNVTCHFCIVGCGYHAYTWPINKQGGTDPQNNIFGVDLSEQQQAESDAWYSPSMYNVVKQDGRDVHVVIKPDHECVVNSGLGSVRGARMAETSFSEARNTQQQRLTDPLVWRYGQMQPTSWDDALDLVARVTAKIVKEKGEDALIVSAFDHGGAGGGYENTWGTGKLYFEAMKVKNIRIHNRPAYNSEVHGTRDMGVGELNNCYEDAELADTIVAVGTNALETQTNYFLNHWIPNLRGESLGKKKELMPEEPHEAGRIIIVDPRRTVTVNACEQTAGADNVLHLAINSGTDLALFNALFTYIADKGWVDRDFIDKSTLREGTARPPLYPARGVSEANPGHLSSFEDAVEGCRMSIEEAAEITGLDAAQIIKAAEWIGMPKEGGKRRRVMFGYEKGLIWGNDNYRTNGALVNLALATGNIGRPGGGVVRLGGHQEGYVRPSDAHVGRPAAYVDQLLIGGQGGVHHIWGCDHYKTTLNAHEFKRVYKKRTDMVKDAMSAAPYGDREAMVNAIVDAINQGGLFAVNVDIIPTKIGEACHVILPAATSGEMNLTSMNGERRMRLTERYMDPPGQSMPDCLIAARLANTMERVLTEMGDVGYAAQFKGFDWQTEEDAFMDGYNKNAHGGEFVTYERLSAMGTNGFQEPATGFTDGKIEGTQRLYTDGVFSTDDGKARFMDAPWRGLQAPGKQQQKDSHKYLINNGRANVVWQSAYLDQENDFVMDRFPYPFIEMNPEDMAEAGLKEGDLVEIYNDAGATQAMAYPTPTARRGETFMLFGFPTGVQGNVTSAGTNELIIPNYKQTWGNIRKISDAPRNVAHLSFKSKEYQS 5nqk H 3.25 BS01 III P 1 M5 Y7 F9 M45 Y59 E63 K66 V67 H70 D77 T80 Y84 R97 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 F9 M45 Y59 E63 K66 V67 H70 D77 T80 Y84 R97 Y99 Y116 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 5nqk A 3.25 BS01 III P 1 G29 Q31 Y51 G27 Q29 Y49 EVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMSIYSNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAGGGGADGLTFGKGTHLIIQPYIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP 5nr3 A 2.30 BS01 95E A 1 I233 F236 W239 W263 D266 S297 I18 F21 W24 W48 D51 S82 2.1.1.37 Q9UBC3 EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPDSLEDQLKPMLEWAHGGFKPTGIEGLKP 5nr3 B 2.30 BS01 95E B 1 F236 W239 W263 D266 S297 F21 W24 W48 D51 S82 2.1.1.37 Q9UBC3 EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPDSLEDQLKPMLEWAHGGFKPTGIEGLKP 5nrh A 1.30 BS01 AMP A 1 K104 P119 F146 K148 E184 K185 S186 I187 E192 F214 Y215 L274 E275 K102 P117 F144 K146 E182 K183 S184 I185 E190 F212 Y213 L272 E273 6.3.2.4 A3NZL3 GIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nrh B 1.30 BS01 AMP B 1 K104 F146 K148 S155 E184 K185 S186 I187 E192 F214 Y215 L274 E275 K101 F143 K145 S152 E181 K182 S183 I184 E189 F211 Y212 L271 E272 6.3.2.4 A3NZL3 IDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nri A 1.50 BS02 DAL A 1 R260 S286 L287 P288 R259 S285 L286 P287 6.3.2.4 A3NZL3 SGIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nri A 1.50 BS03 DAL A 2 H70 R260 N277 H69 R259 N276 6.3.2.4 A3NZL3 SGIDPKRFGKVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAQDIVAKLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVLSLTLD 5nrs A 2.30 BS01 962 A 1 F236 W239 W263 D266 K268 F22 W25 W49 D52 K54 2.1.1.37 Q9UBC3 SEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPSSLEDQLKPMLEWAHGGFKPTGIEGLKPN 5nrs B 2.30 BS01 962 B 1 I233 F236 W239 W263 D266 I19 F22 W25 W49 D52 2.1.1.37 Q9UBC3 SEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPSSLEDQLKPMLEWAHGGFKPTGIEGLKPN 5ntc A 2.25 BS01 6L7 A 1 Y150 F151 Y154 Q160 M163 R169 G193 C194 G195 I198 L199 E215 A216 G241 K242 V243 E244 E258 M260 E267 M269 S272 Y5 F6 Y9 Q15 M18 R24 G48 C49 G50 I53 L54 E70 A71 G96 K97 V98 E99 E113 M115 E122 M124 S127 2.1.1.319 Q9WVG6 SAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSE 5ntc B 2.25 BS01 6L7 B 1 Y150 F151 Y154 M163 R169 D191 G193 C194 G195 I198 L199 V214 E215 A216 G241 K242 V243 E244 E258 M260 E267 M269 S272 Y5 F6 Y9 M18 R24 D46 G48 C49 G50 I53 L54 V69 E70 A71 G96 K97 V98 E99 E113 M115 E122 M124 S127 2.1.1.319 Q9WVG6 SAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 5ntc B 2.25 BS02 DXE C 1 D458 T460 D313 T315 2.1.1.319 Q9WVG6 SAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 5ntc D 2.25 BS01 6L7 D 1 Y150 F151 Y154 Q160 M163 R169 G193 C194 G195 S196 I198 L199 V214 E215 A216 G241 K242 V243 E244 E258 M260 E267 M269 S272 Y5 F6 Y9 Q15 M18 R24 G48 C49 G50 S51 I53 L54 V69 E70 A71 G96 K97 V98 E99 E113 M115 E122 M124 S127 2.1.1.319 Q9WVG6 SAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 5ntj A 1.56 BS01 III B 1 F129 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 E230 Y235 P236 F239 A240 D241 P243 I246 Y247 F132 R136 K171 P172 E173 F190 L201 C202 G203 T204 P205 E206 Y207 L208 E233 Y238 P239 F242 A243 D244 P246 I249 Y250 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTDDYEEEEIRVSINEKCGKEFTEF 5ntj A 1.56 BS02 RIP B 1 E127 F129 S130 D328 E130 F132 S133 D328 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTDDYEEEEIRVSINEKCGKEFTEF 5nuu A 2.50 BS01 9A5 A 1 Y70 W84 Y121 E199 W279 F330 Y334 W432 M436 I439 H440 Y442 Y67 W81 Y118 E196 W276 F327 Y331 W429 M433 I436 H437 Y439 3.1.1.7 P04058 SELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 5nux A 2.30 BS01 FMN A 1 S22 P23 M24 D25 A58 Q100 H172 H175 R225 V294 G295 L296 G318 R319 S21 P22 M23 D24 A57 Q99 H171 H174 R224 V293 G294 L295 G317 R318 B0JDW3 ALLFTPLELGGLRLKNRLAMSPMDQYSATLEGEVTDWHLLHYPTRALGGVGLILVEATAVEPLGRTSPYDLGIWSEDHLPGLKELARRIREAGAVPGIQLAHAGRKAGTARPWEGGKPLGWRVVGPSPIPFDEGYPVPEPLDEAGMERILQAFVEGARRALRAGFQVIELHMAHGYLLSSFLSPLSNQRTDAYGGSLENRMRFPLQVAQAVREVVPRELPLFVRVSATDWGEGGWSLEDTLAFARRLKELGVDLLDCSSGGVVLRVRIPLAPGFQVPFADAVRKRVGLRTGAVGLITTPEQAETLLQAGSADLVLLGRVLLRDPYFPLRAAKALGVAPEVPPQYQRGF 5nv0 A 2.40 BS01 9AH A 1 I233 F236 W239 W263 D266 K268 S297 I19 F22 W25 W49 D52 K54 S83 2.1.1.37 Q9UBC3 SEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPSSLEDQLKPMLEWAHGGFKPTGIEGLKPN 5nv7 A 2.57 BS01 9AK A 1 F236 W263 D266 F22 W49 D52 2.1.1.37 Q9UBC3 SEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPSLEDQLKPMLEWAHGGFKPTGIEGLKPN 5nv7 B 2.57 BS01 9AK B 1 W239 W263 D266 W24 W48 D51 2.1.1.37 Q9UBC3 EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPLEDQLKPMLEWAHGGFKPTGIEGLKPN 5nvo A 2.40 BS01 CHT A 1 F236 W239 W263 D266 F21 W24 W48 D51 2.1.1.37 Q9UBC3 EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFPEDQLKPMLEWAHGGFKPTGIEGLKP 5nw8 A 2.09 BS01 III D 1 F129 R133 K168 P169 E170 F187 G200 T201 P202 E203 E230 Y235 P236 F239 A240 D241 I246 Y247 F119 R123 K158 P159 E160 F177 G190 T191 P192 E193 E220 Y225 P226 F229 A230 D231 I236 Y237 2.7.11.11 P25321 EQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5nwo A 1.45 BS01 9CK A 1 R55 F60 M61 Q63 G72 A101 N102 T107 G109 Q111 F113 L122 H126 R54 F59 M60 Q62 G71 A100 N101 T106 G108 Q110 F112 L121 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5nx1 D 1.85 BS01 III B 1 A16 M17 Y22 F23 F33 F34 Y35 G36 C38 G40 N41 R42 N43 C55 A1 M2 Y7 F8 F18 F19 Y20 G21 C23 G25 N26 R27 N28 C40 P05067 AMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 5nx3 D 2.30 BS01 III B 1 A16 L17 Y22 F23 F33 V34 Y35 G36 C38 G40 N41 R42 N43 C55 A1 L2 Y7 F8 F18 V19 Y20 G21 C23 G25 N26 R27 N28 C40 P05067 ALFFRWYFDVTEGKCAPFVYGGCGGNRNNFDTEEYCMAVCGS 5nx9 A 2.30 BS04 AMP D 1 R20 Y21 R303 R12 Y13 R289 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKA 5nx9 A 2.30 BS05 FUM D 1 G288 K295 N297 G280 K281 N283 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKA 5nx9 B 2.30 BS02 2SA B 1 R85 H86 D87 T111 S112 Q241 L331 S334 A335 R338 R78 H79 D80 T104 S105 Q234 L324 S327 A328 R331 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELC 5nx9 B 2.30 BS03 2SA C 1 R20 Y21 S289 S290 K295 N297 M299 R303 R13 Y14 S282 S283 K288 N290 M292 R296 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELC 5nx9 C 2.30 BS01 2SA B 1 R20 Y21 N297 M299 R303 R12 Y13 N275 M277 R281 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPY 5nx9 C 2.30 BS02 2SA C 1 R85 H86 D87 T111 S112 Q241 R329 L331 S334 A335 R338 R77 H78 D79 T103 S104 Q233 R307 L309 S312 A313 R316 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPY 5nx9 D 2.30 BS02 FUM A 1 S289 S290 K295 N297 S282 S283 K288 N290 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nxa A 2.40 BS03 SSS D 1 R20 Y21 K295 N297 M299 R303 R13 Y14 K275 N277 M279 R283 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nxa B 2.40 BS02 SSS B 1 T111 S112 Q241 R329 L331 S334 A335 R338 T42 S43 Q172 R260 L262 S265 A266 R269 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nxa B 2.40 BS03 FUM B 1 S289 S290 A291 M292 K295 N297 S220 S221 A222 M223 K226 N228 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nxa C 2.40 BS01 SSS B 1 R20 Y21 K295 N297 M299 R303 R12 Y13 K276 N278 M280 R284 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 5nxa C 2.40 BS02 FUM B 1 H86 T111 S112 Q241 H78 T103 S104 Q233 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 5nxa C 2.40 BS03 AMZ C 1 R85 H86 D87 S112 Q241 R329 L331 S334 A335 R338 R77 H78 D79 S104 Q233 R310 L312 S315 A316 R319 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 5nxa C 2.40 BS04 SSS D 1 T158 H159 T150 H151 4.3.2.2 SPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAEL 5nxa E 2.40 BS01 FUM E 1 S289 S290 M292 K295 N297 S282 S283 M285 K288 N290 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nxa F 2.40 BS01 SSS F 1 E81 R85 H86 D87 T111 S112 Q241 R329 L331 S334 A335 R338 E74 R78 H79 D80 T104 S105 Q234 R311 L313 S316 A317 R320 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5nxa H 2.40 BS03 SSS H 1 R20 Y21 S289 S290 A291 M292 K295 N297 M299 R303 R13 Y14 S282 S283 A284 M285 K288 N290 M292 R296 4.3.2.2 GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL 5ny7 A 1.31 BS01 NCA A 1 E41 K111 Y115 E119 A145 Y146 E149 A170 L171 E49 K119 Y123 E127 A153 Y154 E157 A178 L179 3.5.1.4 D0VWZ1 GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPELFGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQRGITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSLLVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGITLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPDADYLQDRRAELHRNWL 5ny7 A 1.31 BS02 NCA A 2 R65 P86 T95 E97 S108 R73 P94 T103 E105 S116 3.5.1.4 D0VWZ1 GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPELFGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQRGITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSLLVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGITLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPDADYLQDRRAELHRNWL 5ny7 A 1.31 BS03 NCA A 3 L-6 V-5 L2 V3 3.5.1.4 D0VWZ1 GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPELFGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQRGITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSLLVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGITLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPDADYLQDRRAELHRNWL 5nyc A 1.51 BS02 CNV A 2 K111 Y115 A145 Y146 E149 T169 A170 L171 K119 Y123 A153 Y154 E157 T177 A178 L179 3.5.1.4 D0VWZ1 GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPELFGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQRGITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSLLVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGITLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPADYLQDRRAELHRNWL 5nyc A 1.51 BS03 CNV A 3 P15 Q16 A64 R67 P23 Q24 A72 R75 3.5.1.4 D0VWZ1 GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPELFGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQRGITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSLLVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGITLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPADYLQDRRAELHRNWL 5nye A 1.55 BS02 ROP A 2 Y115 E149 L171 E175 Y123 E157 L179 E183 3.5.1.4 D0VWZ1 GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPELFGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQRGITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSLLVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGITLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPADYLQDRRAELHRNWL 5nyi A 1.44 BS01 2EQ A 1 L48 N51 T52 A55 K58 D93 I96 G97 M98 D102 L107 G108 F138 T184 V186 L33 N36 T37 A40 K43 D78 I81 G82 M83 D87 L92 G93 F123 T169 V171 P07900 EVETFAFQAEIAQLMTLIINTFYTNKEIFLRELITNTTDALDKIRYETLTDPTKLDTGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKTGTKAFMEALQAGADITMIGQFGVGFYTAYLVAEKVTVITKHNDDEQYAWETTAGGTFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHTQFIGYPITLFVEE 5nz0 A 1.83 BS01 ZLD A 1 M102 W103 G106 I107 F110 M142 W145 Y148 T149 V152 N176 N179 L183 W207 M78 W79 G82 I83 F86 M118 W121 Y124 T125 V128 N152 N155 L159 W183 P9WMC1 GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGE 5nz1 A 2.33 BS01 9EN A 1 L87 W103 G106 I107 F110 F114 W138 M142 W145 Y148 T149 N176 N179 E180 L183 W207 L66 W79 G82 I83 F86 F90 W114 M118 W121 Y124 T125 N152 N155 E156 L159 W183 P9WMC1 GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGEN 5nz1 C 2.33 BS01 9EN C 1 M102 W103 G106 I107 F110 F114 M142 W145 Y148 T149 V152 N176 N179 E180 W207 M76 W77 G80 I81 F84 F88 M116 W119 Y122 T123 V126 N150 N153 E154 W181 P9WMC1 GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAEDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGEN 5nz1 D 2.33 BS01 9EN D 1 L87 M102 W103 G106 I107 F110 F114 W138 M142 W145 T149 N176 N179 E180 L66 M81 W82 G85 I86 F89 F93 W117 M121 W124 T128 N155 N158 E159 P9WMC1 GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGE 5nzz E 2.60 BS01 AGS E 1 S37 V38 A51 K53 E71 T106 H107 M109 D112 S154 N155 D168 G170 S29 V30 A43 K45 E63 T98 H99 M101 D104 S146 N147 D160 G162 2.7.11.24 P47811 ERPTFYRQELNKTIWEVPERYQNLSPVGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL 5nzz F 2.60 BS01 AGS F 1 S37 V38 A51 K53 E71 I84 T106 H107 L108 M109 D112 S154 N155 L167 D168 S27 V28 A41 K43 E61 I74 T96 H97 L98 M99 D102 S144 N145 L157 D158 2.7.11.24 P47811 RPTFYRQELNKTIWEVPERYQNLSPVSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL 5nzz G 2.60 BS03 MG G 2 H174 Y323 H165 Y314 2.7.11.24 P47811 RPTFYRQELNKTIWEVPERYQNLSPVGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL 5nzz H 2.60 BS01 AGS H 1 S37 V38 A51 E71 H107 M109 D112 S154 N155 L167 D168 G170 S26 V27 A40 E60 H96 M98 D101 S143 N144 L156 D157 G159 2.7.11.24 P47811 RPTFYRQELNKTIWEVPERYQNLSPSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKSSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP 5nzz H 2.60 BS02 MG H 1 S154 N155 D168 S143 N144 D157 2.7.11.24 P47811 RPTFYRQELNKTIWEVPERYQNLSPSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKSSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP 5nzz H 2.60 BS03 MG H 2 D145 H174 D134 H163 2.7.11.24 P47811 RPTFYRQELNKTIWEVPERYQNLSPSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKSSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP 5o0e A 1.50 BS02 M77 A 1 F54 V57 A70 M120 E121 Y122 V123 E127 E170 N171 L173 T183 D184 F327 F57 V60 A73 M123 E124 Y125 V126 E130 E173 N174 L176 T186 D187 F330 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5o0j A 1.81 BS01 8BR A 1 E198 R200 N295 H345 T346 Y347 K430 V431 V432 P435 T438 I441 I445 E194 R196 N291 H341 T342 Y343 K426 V427 V428 P431 T434 I437 I441 2.7.1.147 O58328 TNWESLYEKALDKVEASIRKVRGVLLAYNTNIDAIKYLKREDLEKRIEKVGKEEVLRYSEELPKEIETIPQLLGSILWSIKRGKAAELLVVSREVREYMRKWGWDELRMGGQVGIMANLLGGVYGIPVIAHVPQLSELQASLFLDGPIYVPTFERGELRLIHPREFRKGEEDCIHYIYEFPRNFKVLDFEAPRENRFIGAADDYNPILYVREEWIERFEEIAKRSELAIISGLHPLTQENHGKPIKLVREHLKILNDLGIRAHLEFAFTPDEVVRLEIVKLLKHFYSVGLNEVELASVVSVMGEKELAERIISKDPADPIAVIEGLLKLIKETGVKRIHFHTYGYYLALTREKGEHVRDALLFSALAAATKAMKGNIEKLSDIREGLAVPIGEQGLEVEKILEKEFSLRDGIGSIEDYQLTFIPTKVVKKPKSTVGIGDTISSSAFVSEFSLH 5o0j A 1.81 BS02 8BR A 2 W82 R86 K88 A89 A90 F272 W78 R82 K84 A85 A86 F268 2.7.1.147 O58328 TNWESLYEKALDKVEASIRKVRGVLLAYNTNIDAIKYLKREDLEKRIEKVGKEEVLRYSEELPKEIETIPQLLGSILWSIKRGKAAELLVVSREVREYMRKWGWDELRMGGQVGIMANLLGGVYGIPVIAHVPQLSELQASLFLDGPIYVPTFERGELRLIHPREFRKGEEDCIHYIYEFPRNFKVLDFEAPRENRFIGAADDYNPILYVREEWIERFEEIAKRSELAIISGLHPLTQENHGKPIKLVREHLKILNDLGIRAHLEFAFTPDEVVRLEIVKLLKHFYSVGLNEVELASVVSVMGEKELAERIISKDPADPIAVIEGLLKLIKETGVKRIHFHTYGYYLALTREKGEHVRDALLFSALAAATKAMKGNIEKLSDIREGLAVPIGEQGLEVEKILEKEFSLRDGIGSIEDYQLTFIPTKVVKKPKSTVGIGDTISSSAFVSEFSLH 5o0j A 1.81 BS03 GLC A 1 N33 N35 D37 E91 G114 G115 Q116 I119 H179 I202 V439 D443 N29 N31 D33 E87 G110 G111 Q112 I115 H175 I198 V435 D439 2.7.1.147 O58328 TNWESLYEKALDKVEASIRKVRGVLLAYNTNIDAIKYLKREDLEKRIEKVGKEEVLRYSEELPKEIETIPQLLGSILWSIKRGKAAELLVVSREVREYMRKWGWDELRMGGQVGIMANLLGGVYGIPVIAHVPQLSELQASLFLDGPIYVPTFERGELRLIHPREFRKGEEDCIHYIYEFPRNFKVLDFEAPRENRFIGAADDYNPILYVREEWIERFEEIAKRSELAIISGLHPLTQENHGKPIKLVREHLKILNDLGIRAHLEFAFTPDEVVRLEIVKLLKHFYSVGLNEVELASVVSVMGEKELAERIISKDPADPIAVIEGLLKLIKETGVKRIHFHTYGYYLALTREKGEHVRDALLFSALAAATKAMKGNIEKLSDIREGLAVPIGEQGLEVEKILEKEFSLRDGIGSIEDYQLTFIPTKVVKKPKSTVGIGDTISSSAFVSEFSLH 5o0y A 2.86 BS01 AGS A 1 L468 R470 G471 G472 S474 V476 A489 K491 E545 Y546 C547 L13 R15 G16 G17 S19 V21 A34 K36 E90 Y91 C92 2.7.11.1 Q86UE8 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLP 5o1s A 1.90 BS01 9HB A 1 C599 W602 I633 R667 C177 W180 I211 R245 2.7.11.1 P18654 SIQFTDGYEVKEDISVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCNFVAPEVLERQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNR 5o1s A 1.90 BS02 9HB A 2 C436 A449 K451 T493 N544 C560 C17 A30 K32 T74 N125 C141 2.7.11.1 P18654 SIQFTDGYEVKEDISVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCNFVAPEVLERQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNR 5oiz A 2.70 BS01 1S6 A 1 G336 S337 K340 W374 N377 S395 N397 F450 K547 G549 T550 Q552 G237 S238 K241 W275 N278 S296 N298 F351 K448 G450 T451 Q453 P59676 29357220 TVPAKRGTIYDRNGVPIAEDATSYNVYAVIDYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 5oj0 A 2.66 BS01 9WT A 1 S337 K340 R372 W374 N377 S395 N397 Q452 T526 S548 G549 T550 A551 Q552 S254 K257 R289 W291 N294 S312 N314 Q369 T443 S465 G466 T467 A468 Q469 P59676 29357220 QTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 5oj1 A 2.85 BS01 1S6 A 1 G336 S337 K340 W374 N377 S395 N397 F450 Q452 G549 T550 Q552 Y568 G261 S262 K265 W299 N302 S320 N322 F375 Q377 G474 T475 Q477 Y493 P59676 29357220 VPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD 5ojl A 1.56 BS01 9X5 A 1 A125 M129 M182 A121 M125 M176 Q0CCT3 29024400 TTTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGGETYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSGGVSATEFLGLLAPWLQAMTGYLGLLARQIDDVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYF 5ojl A 1.56 BS02 TXP A 1 G14 L15 G16 A17 M18 N37 R38 T39 K42 C70 L71 L72 A76 Q79 T97 N98 I123 A125 P127 G10 L11 G12 A13 M14 N33 R34 T35 K38 C66 L67 L68 A72 Q75 T93 N94 I119 A121 P123 Q0CCT3 29024400 TTTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIMATPDMIGAPHAVILYSGGGETYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYGLFAGFLHATALVRSGGVSATEFLGLLAPWLQAMTGYLGLLARQIDDVYTAQTSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYF 5u2o A 1.46 BS01 ZN A 1 C98 C114 H115 H143 C98 C114 H115 H143 MLPEFPKIAVVAGSEAESVFRVVDIGTGDVVYEGRLSDSVYDDASGDTVRHADFGEWKRPGSYSVTVGRSSSAPFRIGNDVYRAPLIQAARSYTLARCGVAIDDPVTGLRHDVCHAQDKQAMLFFEDPFHRQGDPIDVSGGWHDAGDYGKYVPTGAVAAAQLMLAWEMRPELWRSLSLSLPAGLSEPERRAGLPDLLVEIKYELDWLLRMQRPDGAVYLKVAGGAWPGYIRPEEDTADRYVFGLSTYGTAQFAGAAAMGARVYAPFLPDYARKLLDAAIRAQRYLEQHPDPEFRYDEGQNNGSGPYEKRTDREERFWAAAELLRTTDDARYDAYIREHFSDFLEGKTSAVFWGNTVLLGQWAYVNAERADADHKASVRASLTAYADELVRWASANGYRSVLRPTDYFWGSAREAMGRAQALLLADAVAPNRAYLETALDQAHWLFGRNAAGTSFMTGIGMHSPQKPHHRLVASTQTLIPGLVVGGPNAQGGDPIMDRLLRESDPRVFPAKAYVDDWEAYSVNEPAIDYTAPAVFVLTRFAEDR 5vz6 A 2.60 BS01 9TV A 1 V108 Y181 Y183 D186 Y188 K223 F227 L228 W229 L234 V105 Y178 Y180 D183 Y185 K220 F224 L225 W226 L231 2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P04585 SPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 5vzs A 1.71 BS01 9U4 A 1 W81 F83 V87 L92 L94 Y97 Y139 N140 I146 W40 F42 V46 L51 L53 Y56 Y98 N99 I105 O60885 STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5vzs B 1.71 BS01 9U4 B 1 Q78 W81 P82 F83 L92 N140 I146 M149 Q37 W40 P41 F42 L51 N99 I105 M108 O60885 STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5w6e A 1.90 BS02 0NY A 1 Y222 H223 M336 H373 P374 L388 E391 F392 L409 Q421 F424 Y73 H74 M187 H224 P225 L239 E242 F243 L260 Q272 F275 3.1.4.17 Q01064 29718668 YSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQVVSFRSTWVKRIQENKQKWKERAAS 5w8b A 1.60 BS02 A9J A 1 H94 V121 V143 L198 T199 W209 H91 V118 V139 L194 T195 W205 4.2.1.1 P00918 29423818 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wp2 A 1.44 BS01 HEM A 1 M62 M86 I102 H146 F230 A233 G234 S237 T238 F241 L274 F280 L284 R286 L309 A337 F338 G339 H343 F344 C345 P346 G347 L350 G351 M60 M84 I100 H144 F228 A231 G232 S235 T236 F239 L272 F278 L282 R284 L307 A335 F336 G337 H341 F342 C343 P344 G345 L348 G349 1.14.21.9 P9WPP6 29090577 ATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW 5wp2 A 1.44 BS02 YTT A 1 M62 V78 V82 V83 N85 A167 F168 W182 T229 A233 R386 M60 V76 V80 V81 N83 A165 F166 W180 T227 A231 R384 1.14.21.9 P9WPP6 29090577 ATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW 5wp2 A 1.44 BS03 CYN A 1 A233 S237 R386 A231 S235 R384 1.14.21.9 P9WPP6 29090577 ATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW 5xni A 3.22 BS01 DGL A 1 M14 R53 S87 C88 T89 K167 G194 S195 T196 E197 M10 R49 S83 C84 T85 K163 G190 S191 T192 E193 Q9RNB4 LPILGVLGGMGPVVTAEFLKSIYEYNPFIDKEQESPNVIVFSFPSAPDRTGSIDSGKEREFIDFIQVNLEHLNKLADCIVIGSCTAHYALPQIPENLKDKLISLIKIADQELQEYNEPTLLLASTGTYQKKLFQEGCTTADLIISLSESDQKLIHEMIYKVLKRGHDPLSILRDIEALLEKYNTRSYISGSTEFHLLTKSLKLKGIDSIKAIDPLSTIAQNFSQLII 5xnk A 3.40 BS01 2AS A 1 M14 R53 S87 C88 T89 K167 G194 C195 T196 E197 M10 R49 S83 C84 T85 K163 G190 C191 T192 E193 Q9RNB4 LPILGVLGGMGPVVTAEFLKSIYEYNPFIDKEQESPNVIVFSFPSAPDRTGSIDSGKEREFIDFIQVNLEHLNKLADCIVIGSCTAHYALPQIPENLKDKLISLIKIADQELQEYNEPTLLLASTGTYQKKLFQEGCTTADLIISLSESDQKLIHEMIYKVLKRGHDPLSILRDIEALLEKYNTRSYISGCTEFHLLTKSLKLKGIDSIKAIDPLSTIAQNFSQLII 5xoq A 1.87 BS01 III C 1 K44 T71 S72 G73 N74 T75 M122 Q143 G177 T178 G216 R217 H218 Q221 G222 A225 F227 K45 T72 S73 G74 N75 T76 M123 Q144 G178 T179 G217 R218 H219 Q222 G223 A226 F228 2.5.1.47 D5STP0 HMPIFKDNSESIGRTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGKLKPGMHVVEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGADGMKGAISKAEELAAQPGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTGGTITGVARFLKHEKKHPVHVVAVEPAASPVLAGGPAGRHKIQGIGAGFVPDTFDRSVVDEILSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPDAGERYLSTALFENLR 5y18 A 2.20 BS01 III B 1 H81 E83 V84 F87 R91 A121 K122 L123 Y124 V125 I127 N128 H26 E28 V29 F32 R36 A66 K67 L68 Y69 V70 I72 N73 Q9UER7 28875424 KKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAK 5yij A 3.18 BS01 NAI A 1 Q713 N714 F719 N723 Q727 R729 R766 G767 L768 N769 S820 T822 V828 W832 E862 Q480 N481 F486 N490 Q494 R496 R533 G534 L535 N536 S587 T589 V595 W599 E629 Q6RCR0 GFSLYTDDTVKAAAQYAYDNYLGKPYTGSVESAPANFGGRMVYRQHHGLSHTLRTMAYAELIVEEARKAKLRGETLGKFKDGRTIADVTPQELKKIMIAQAFFVAGRDDEASDAKNYQKYHEQSRDAFLKYVKDNESTLIPDVFKDQEDVNFYARVIEDKSHDWESTPAHVLINQGHMVDLVRVKQPPESFLQRYFSSMQRWIGSQATEAVFGIQRQFFHATYEVVAGFDSDNKEPHLVVSGLGRYVIGEDGQPIREAPKKGQKEGDLKVFPQTYKNERLMRVDEFLKLPEIQNTFPGSGKHLQGGMPGMNEMDYWNRLNSLNRARCENDVDFCLKQLQTAHDKAKIEPIKQAFQSSKGKERRQPNVDEIAAARIIQQILANPDCIHDDHVLINGQKLEQQFFRDLLAKCEMAVVGSLLNDTDIGNIDTLMRHEKDTEFHSTNPEAVPVKIGEYWINDQRINNSSGNITQKKHDLIFLMQNDAWYFSRVNAIAQNRDKGSTFKEVLITTLMTPLTSKALVDTSQAKPPTRLFRGLNLSEEFTKGLIDQANAMIANTTERLFTDHSPEAFKQIKLNDLSKMSGRTNASTTTEIKLVKETWDSNVIFEMLDPDGLLHSKQVGRHGEGTESEFSVYLPEDVALVPVKVTLDGKTQKGENRYVFTFVAVKSPDFTPRHESGYAVEPFLRMQAAKLAEVKSSIEKAQRAPDLETIFNLQNEVEAVQYSHLSTGYKNFLKNTVGPVLENSLSGLMESDTDTLSKALAAFPSDTQWSAFNFEEARQAKRQMDAIKQMVGNKVVLDALTQCQDALEKQNIAGALDALKKIPSEKEMGTIRRELREQIQSARQELESLQRAVVTPVVTDEKKVRERYDALIENTSKKITELETGKLPNLDAVKKGISNLSNLKQEVTVLRNEKIRMHVGTDKVDFSDVEKLEQQIQVIDTKLADAYLLEVTKQISALE 5yjl A 2.70 BS01 NAP A 1 C144 Q214 A256 V259 A286 G287 K288 M289 N309 R310 S311 R314 L332 S348 T349 A350 S351 I380 S381 V382 C51 Q121 A163 V166 A188 G189 K190 M191 N211 R212 S213 R216 L234 S250 T251 A252 S253 I282 S283 V284 1.2.1.70 P42804 RSSIVVIGLSIHTAPVEMREKLAIPEAEWPRAIAELCGLNHIEEAAVLSTCNRMEIYVLALSQHRGVKEVTEWMSKTSGIPVSEICQHRFLLYNKDATQHIFEVSAGLDSLVLGEGQILAQVKQVVKVGQGVNGFGRNISGLFKHAITVGKRVRTETNIASGAVSVSSAAVELALMKLPSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIREEMPGIEIIYRPLDEMLACASEADVVFTSTASETPLFLKEHVENLPQASPEVGGLRHFVDISVPRNVGSCVGEVETARVYNVDDLKEVVAANKEDRMRKAMEAQTIITEESTQFEAWRDSLETVPTIKKLRAYAERIRVAELEKCMSKKTTRAVDDLSRGIVNRFLHGPMQHLTLSETLENMHALNRMYG 5yjl B 2.70 BS01 NAP B 1 C144 A256 V259 A286 G287 K288 M289 N309 R310 S311 R314 L332 S348 T349 A350 S351 I380 V382 C50 A162 V165 A186 G187 K188 M189 N209 R210 S211 R214 L232 S248 T249 A250 S251 I280 V282 1.2.1.70 P42804 SSIVVIGLSIHTAPVEMREKLAIPEAEWPRAIAELCGLNHIEEAAVLSTCNRMEIYVLALSQHRGVKEVTEWMSKTSGIPVSEICQHRFLLYNKDATQHIFEVSAGLDSLVLGEGQILAQVKQVVKVGQGVNGFGRNISGLFKHAITVGKRVRTETNIASGAVSVSSAAVELALMKLPARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIREEMPGIEIIYRPLDEMLACASEADVVFTSTASETPLFLKEHVENLPQASPEVGGLRHFVDISVPRNVGSCVGEVETARVYNVDDLKEVVAANKEDRMRKAMEAQTIITEESTQFEAWRDSLETVPTIKKLRAYAERIRVAELEKCMSKMKTTRAVDDLSRGIVNRFLHGPMQHLRCDGSRTLSETLENMHALNRMY 5ywb A 5.20 BS01 ADP A 1 I182 K185 Y330 F333 G334 I151 K154 Y299 F302 G303 Q61743 29594720 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITLRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNGIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDRSLL 5yz2 A 1.75 BS01 AMP A 1 Q78 I80 H100 R102 F103 P104 M165 T180 D183 Q16 I18 H38 R40 F41 P42 M103 T118 D121 P0AE78 29453981 ELALQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 5yz2 B 1.75 BS01 AMP B 1 I74 Q78 M79 I80 H100 S101 R102 F103 P104 M165 L178 T180 E182 D183 I12 Q16 M17 I18 H38 S39 R40 F41 P42 M103 L116 T118 E120 D121 P0AE78 29453981 ELALQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEKGQFL 5yz7 A 1.90 BS01 94X A 1 F78 S147 F186 Y209 C241 V244 F245 F25 S94 F133 Y156 C188 V191 F192 3.1.-.- Q10QA5 29727000 AKLLQILNVRVVGSGERVVVLSHGFGTDQSAWSRVLPYLTRDHRVVLYDLVCAGSVNPDHFDFRRYDNLDAYVDDLLAILDALRIPRCAFVGHSVSAMIGILASIRRPDLFAKLVLIGASPRFLNDSDYHGGFELEEIQQVFDAMGANYSAWATGYAPLAVGADVPAAVQEFSRTLFNMRPDISLHVCQTVFKTDLRGVLGMVRAPCVVVQTTRDVSVPASVAAYLKAHLGGRTTVEFLQTEGHLPHLSAPSLLAQVLRRALARY 5yz7 B 1.90 BS01 94X B 1 F78 S147 F176 F186 Y209 C241 V244 F245 S270 F25 S94 F123 F133 Y156 C188 V191 F192 S217 3.1.-.- Q10QA5 29727000 AKLLQILNVRVVGSGERVVVLSHGFGTDQSAWSRVLPYLTRDHRVVLYDLVCAGSVNPDHFDFRRYDNLDAYVDDLLAILDALRIPRCAFVGHSVSAMIGILASIRRPDLFAKLVLIGASPRFLNDSDYHGGFELEEIQQVFDAMGANYSAWATGYAPLAVGADVPAAVQEFSRTLFNMRPDISLHVCQTVFKTDLRGVLGMVRAPCVVVQTTRDVSVPASVAAYLKAHLGGRTTVEFLQTEGHLPHLSAPSLLAQVLRRALARY 5z06 A 2.10 BS01 CA A 1 E29 N30 T66 N69 D192 E9 N10 T46 N49 D172 A6LGF6 29763309 KPYDYVFFENSLMKGDYFYSQAKYTSPSWIKNARHHLPVAGSVAFTPGNSLELTYVSAPGGDWYSEIQYCPVRGNDFFREPSTLSMQVRLRESMNAAALPNIAIRYADSTYTQYLNLRNYLKDTRPGVWHPVSIPLEDFGLNAVNDTNIKKLAAVALRPGTADGNEYTIYLDDIELLPASLPSVSALNAPVLQEAKAYERHIDIKWIPEDIKYYRIYRSFDGITYQPVAVRRPWMNRYTDFLGEVGKKAYYKVTAVDYALNESNDSQTVSATTYPMTDEQLLDMVQEANFRYYWEGAEPNSGLARENIPGRNDMIATGASGFGIMAIVAGIERGFITREEGVQRFLKITSFLEKADKFHGAVSHFIDGTTGKTVAFFGPKDNGGDLVETSFLFQGLLTARQYFNQENDKEKQIRKSIDNLWKNVEWSWYKQFKDSPYLYWHWSPDQAWVINHKLIGWNETMITYMLAIMGPKYGISPEMYYSGWASQEEYAQEYRADWGRVEDGKMYTNGNTYYGENLKVGVSNGGPLFFIHYSYLGLDPHKFTDKYTNYFENNQKMAKINQRYCIENQGGYVGYGEDCWGLTASDFAWNYQAQEPMPHRDNGTMAPTGALASFPYTPDASMKALRNYYRNHGSFLWGEYGFRDAFNLTVNWVSPLFMGLNQAPVTVMIENYRTNLLWNLFMSHPDVQKGIQKIQSI 5z74 B 1.95 BS01 SUC B 1 F52 R54 D55 M187 D189 Y371 H372 R430 Q433 W435 F36 R38 D39 M171 D173 Y346 H347 R405 Q408 W410 3.2.1.26 Q8YYM9 29578606 DIIEESAWEALEKSILYYKGRPVGTVAAFDNYDQCFVRDFVSSALIFLIKGKTDIVRNFLEETLKLQPKDRQLDAYKPGRGLIPASFKVVSDNGEEYLEADFGEHAIARVTPVDSCLWWILLLRAYVVASKDFSLAYQPEFQTGIRLIMEICLANRFDMYPTLLVPDGACMIDRRLGIYGHPLELQVLFYAALRAAREMLICQGNQDVVEAIDNRLPLLCAHIRQHYWIDINRLNAIYRFVNLFNIYVDSIPYYELDKWLPKKGGYLAGNVGPSQLDTRFFALGNLMAIISDLATEEQSQAIMTLIEDRWEDLVGDMPMKICYPALENEEYRIVTGCDPKNIPWSYHNAGSWPVLMWMLAAASVKAGKPYIAGKAIEIAQARLLEDEWPEYYDGKKGRLIGKQARKYQTWTIAGFLLAAELMKNPSLLSLIS 5za0 A 2.00 BS01 TRE A 1 H191 K192 D193 W194 R195 H190 K191 D192 W193 R194 1.2.1.12 P0A9B2 29717994 TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 5zac B 2.59 BS01 CA A 2 T49 Y67 P68 T49 Y67 P68 P02866 ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVDKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKSETNALHFMFNQFSKDQKDLILQGDATTGTDGNLELTRVSSNGSPQGSSVGRALFYAPVHIWESAVVASFEATFTFLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN 5zac C 2.59 BS03 CA D 1 K116 V187 K116 V181 P02866 ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVDKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKTNALHFMFNQFSKDQKDLILQGDATTGTDGNLELTRVSSNGSPQGSSVGRALFYAPVHIWESSAVVASFEATFTFLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN 5zac D 2.59 BS03 CA D 1 T49 P68 T49 P68 P02866 ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVDKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKTNALHFMFNQFSKDQKDLILQGDATTGTDGNLELTRVSSNGSPQGSSVGRALFYAPVHIWESSAVVASFEATFTFLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN 5zbr B 2.00 BS01 ANP B 1 R11 R13 P14 T105 G106 S107 G108 K109 S110 Y111 S220 R8 R10 P11 T92 G93 S94 G95 K96 S97 Y98 S194 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRD 5zbr B 2.00 BS02 MG B 1 Y95 N96 N321 V358 N360 Y82 N83 N281 V318 N320 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRD 5zbr A 2.00 BS01 ANP A 1 R11 R13 P14 S64 T105 G106 S107 G108 K109 S110 Y111 S220 G256 R8 R10 P11 S51 T92 G93 S94 G95 K96 S97 Y98 S197 G233 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERSNINKSLTTLGLVISALADQGNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDL 5zbr C 2.00 BS02 MG C 1 Y95 N96 N321 A357 V358 N360 Y82 N83 N274 A310 V311 N313 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFWSMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDTLKVREVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERSNINKSLTTLGLVISALADQGANKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDL 5zbs B 2.20 BS01 ANP B 1 R11 R13 P14 T105 G106 G108 K109 S110 Y111 R8 R10 P11 T92 G93 G95 K96 S97 Y98 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFWSMDESVREKCAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERSNINKSLTTLGLVISALADQGAGKNKKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLHHHH 5zbs A 2.20 BS01 ANP A 1 R11 R13 P14 K72 Q104 T105 G106 S107 G108 K109 S110 Y111 S220 R8 R10 P11 K61 Q93 T94 G95 S96 G97 K98 S99 Y100 S195 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINRGQPKIFAYDHCFWSMDESVREKCAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRSSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERNINKSLTTLGLVISALADQGAGKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLH 5zbs A 2.20 BS02 MG A 1 Q76 F80 G121 L122 R125 Q65 F69 G110 L111 R114 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINRGQPKIFAYDHCFWSMDESVREKCAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRSSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERNINKSLTTLGLVISALADQGAGKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLH 5zbs C 2.20 BS02 MG C 1 Y154 N155 R221 I276 Y141 N142 R188 I228 A0A0G2K8Z9 29752968 SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFWSMDESVREKCAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSSSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERNINKSLTTLGLVISALADQGAGKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLHH 5zqs A 1.78 BS01 BXP A 1 D14 F31 W73 D127 Q186 G205 T206 H248 R287 Y503 F504 D14 F31 W73 D127 Q186 G205 T206 H248 R287 Y503 F504 3.2.1.37 P07129 29752942 MKITNPVLKGFNPDPSICRAGEDYYMAVSTFEWFPGVQIYHSKDLIHWRLAARPLQKTSQLDMKGNPDSGGVWAPCLSYADGQFWLIYSDIKVVDGPFKDGHNYLVTADAVDGEWSDPVRLNSSGFDPSLFHDPSGKKYVLNMLWDHREKHHSFAGIALQEYSVSEKKLVGERKVIFKGTPIKLTQAPHLYYINDVYYLLTAEGGTRYEHAATIARSSRIDGPYEVHPDNPILTAFHAPSHPLQKCGHASIVQTHTNEWYLAHLTGRPIHSSKESIFQQRGWCPLGRETAIQKLEWKDGWPYVVGGKEGLLEVEAPAMSVKEFSPTYHIVDEFKDSSLNRHFQTLRIPFTDQIGSVTENPHHLRLYGQESLTSKFTQAFVARRWQSFYFEAETAVSFFPKNFQQAAGLVNYYNTENWTALQVTYDDALGRILELSVCENLAFSQPLIKKIIIPDEIPYVYLKVTVQRETYTYSYSFDQQEWEKIDVPLESTHLSDDFIRGGGYFTGAFVGMQCQDTSGERLPADFKYFRYEET 5zqs A 1.78 BS02 XYP A 1 R173 V175 R173 V175 3.2.1.37 P07129 29752942 MKITNPVLKGFNPDPSICRAGEDYYMAVSTFEWFPGVQIYHSKDLIHWRLAARPLQKTSQLDMKGNPDSGGVWAPCLSYADGQFWLIYSDIKVVDGPFKDGHNYLVTADAVDGEWSDPVRLNSSGFDPSLFHDPSGKKYVLNMLWDHREKHHSFAGIALQEYSVSEKKLVGERKVIFKGTPIKLTQAPHLYYINDVYYLLTAEGGTRYEHAATIARSSRIDGPYEVHPDNPILTAFHAPSHPLQKCGHASIVQTHTNEWYLAHLTGRPIHSSKESIFQQRGWCPLGRETAIQKLEWKDGWPYVVGGKEGLLEVEAPAMSVKEFSPTYHIVDEFKDSSLNRHFQTLRIPFTDQIGSVTENPHHLRLYGQESLTSKFTQAFVARRWQSFYFEAETAVSFFPKNFQQAAGLVNYYNTENWTALQVTYDDALGRILELSVCENLAFSQPLIKKIIIPDEIPYVYLKVTVQRETYTYSYSFDQQEWEKIDVPLESTHLSDDFIRGGGYFTGAFVGMQCQDTSGERLPADFKYFRYEET 5zut A 2.82 BS01 III E 1 N27 V40 D41 R44 V45 D120 I121 E129 L131 E232 A233 P234 A251 P252 N27 V40 D41 R44 V45 D120 I121 E129 L131 E232 A233 P234 A251 P252 P15873 MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFN 6aqp A 1.80 BS01 COA A 1 C92 L152 M161 Y187 N227 L228 N229 K232 L233 A249 P250 S253 F294 A324 F325 H354 C93 L153 M162 Y188 N226 L227 N228 K231 L232 A248 P249 S252 F293 A323 F324 H353 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp A 1.80 BS02 K A 1 Y187 E224 A249 P250 N251 S252 S253 P254 V350 Y188 E223 A248 P249 N250 S251 S252 P253 V349 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp A 1.80 BS03 K A 2 L41 A42 V44 D45 L47 K48 P49 L42 A43 V45 D46 L48 K49 P50 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp A 1.80 BS04 K A 3 K43 D200 E201 E202 I203 A204 P205 K44 D201 E202 E203 I204 A205 P206 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp B 1.80 BS01 COA B 1 C92 L152 M161 Y187 N227 N229 K232 L233 I236 F240 A249 P250 S253 L255 F294 A324 F325 H354 C93 L153 M162 Y188 N225 N227 K230 L231 I234 F238 A247 P248 S251 L253 F292 A322 F323 H352 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp C 1.80 BS04 ACO C 1 C92 L152 M161 Y187 N227 L228 N229 K232 L233 I236 A249 P250 S253 P254 L255 F294 A324 F325 H354 G386 C93 L153 M162 Y188 N228 L229 N230 K233 L234 I237 A250 P251 S254 P255 L256 F295 A325 F326 H355 G387 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp D 1.80 BS01 COA D 1 C92 L152 M161 Y187 N227 N229 K232 L233 I236 A249 P250 S253 P254 L255 F294 A324 F325 C93 L153 M162 Y188 N226 N228 K231 L232 I235 A248 P249 S252 P253 L254 F293 A323 F324 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp D 1.80 BS03 K D 2 K43 D200 E201 E202 I203 A204 K44 D201 E202 E203 I204 A205 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6aqp D 1.80 BS04 K D 3 L41 A42 V44 L47 K48 P49 L42 A43 V45 L48 K49 P50 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6are A 1.75 BS02 NH4 A 1 Y187 A249 P250 S252 V350 Y188 A250 P251 S253 V351 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6are A 1.75 BS03 NH4 A 2 D200 E201 I203 D201 E202 I204 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6are C 1.75 BS03 NH4 C 3 L41 V44 L47 L41 V44 L47 2.3.1.9 Q4WCL5 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6are C 1.75 BS04 ACO C 1 C92 L152 M161 Y187 N227 L228 N229 I236 F240 A249 P250 S253 A324 F325 H354 C384 N385 G386 C92 L152 M161 Y187 N223 L224 N225 I232 F236 A245 P246 S249 A320 F321 H350 C380 N381 G382 2.3.1.9 Q4WCL5 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6are D 1.75 BS01 COA D 1 C92 L152 M161 Y187 N227 N229 L233 I236 F240 A249 P250 S253 F294 A324 H354 C93 L153 M162 Y188 N227 N229 L233 I236 F240 A249 P250 S253 F294 A324 H354 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arf B 1.70 BS03 K B 3 L41 A42 V44 L47 L42 A43 V45 L48 2.3.1.9 Q4WCL5 GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arf D 1.70 BS04 K D 4 D45 G46 L273 N274 L275 D45 G46 L270 N271 L272 2.3.1.9 Q4WCL5 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arg A 1.78 BS01 RB A 1 Y187 A249 P250 S252 P254 V350 Y184 A246 P247 S249 P251 V347 2.3.1.9 Q4WCL5 LPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arg D 1.78 BS04 RB D 4 D45 G46 L273 N274 D45 G46 L270 N271 2.3.1.9 Q4WCL5 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arl A 1.90 BS03 RB A 3 Y187 E224 A249 P250 S252 P254 V350 Y185 E220 A245 P246 S248 P250 V346 2.3.1.9 Q4WCL5 SLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arl D 1.90 BS01 RB D 1 Y187 E224 A249 P250 S252 V350 Y187 E221 A246 P247 S249 V347 2.3.1.9 Q4WCL5 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6arr C 1.82 BS04 CS C 4 D314 A315 I316 D317 K342 D312 A313 I314 D315 K340 2.3.1.9 Q4WCL5 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFKPDVTVTQDEEPKNLNPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL 6bdd A 1.90 BS01 HEM A 1 M1 K2 I5 I78 L85 L86 L96 I99 I103 H104 V107 A114 E115 L116 P117 F119 Y133 S135 R137 M139 F142 G143 L146 M147 M1 K2 I5 I78 L85 L86 L96 I99 I103 H104 V107 A114 E115 L116 P117 F119 Y133 S135 R137 M139 F142 G143 L146 M147 A9DSJ8 29757599 MKGIIFTEFLDLVEDKFGLEMVDKIITQSELESEGVYTSIGTYRFSEMLQLLQNLSANTDVSIDDLLLTYAEHFFSVIEDSYPGLLATYKDPIEMLASIENHIHVEVRKIYPDAELPTFVVEEKTANSLTMIYKSSRAMHHFGLGLMNKTFEHFNSSAEIILEKIKEDGTEVKFIINKNENLYFQ 6bn7 C 3.50 BS01 RN3 B 1 W81 P82 F83 Q84 Q85 V87 L94 Y139 N140 I146 W40 P41 F42 Q43 Q44 V46 L53 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 6boy B 3.33 BS02 RN6 B 1 N351 P352 H353 Y355 H378 S379 W380 W386 W400 F402 N299 P300 H301 Y303 H326 S327 W328 W334 W348 F350 Q96SW2 PNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIP 6boy C 3.33 BS01 RN6 B 1 W81 P82 F83 V87 L94 C136 N140 I146 M149 W40 P41 F42 V46 L53 C95 N99 I105 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 6c0t A 1.98 BS01 EE4 A 1 G367 V368 G369 G370 F371 G372 V374 A388 Q402 H405 I406 V422 M438 E439 A440 C441 E445 E488 V501 D502 G504 G31 V32 G33 G34 F35 G36 V38 A52 Q66 H69 I70 V86 M102 E103 A104 C105 E109 E152 V165 D166 G168 2.7.11.12 Q13976 29769318 EDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF 6c0u A 2.65 BS01 EE4 A 1 L49 G50 T51 G52 S53 F54 G55 R56 V57 A70 L74 T88 M120 E121 Y122 V123 E127 E170 N171 L173 T183 G186 F327 L39 G40 T41 G42 S43 F44 G45 R46 V47 A60 L64 T78 M110 E111 Y112 V113 E117 E160 N161 L163 T173 G176 F317 2.7.11.11 P17612 29769318 EQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 6c1q B 2.90 BS01 III L 1 L178 S181 I182 P199 R261 V262 R264 C274 G275 V276 S279 Y344 T347 G348 M351 D368 V372 L151 S154 I155 P172 R234 V235 R237 C247 G248 V249 S252 Y313 T316 G317 M320 D337 V341 P21730 DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDASPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQSLPSLLRNVLT 6c1q B 2.90 BS02 9P2 B 1 I210 L211 A214 T215 A242 V245 L249 L295 W299 P300 T303 I183 L184 A187 T188 A215 V218 L222 L268 W272 P273 T276 P21730 DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDASPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQSLPSLLRNVLT 6c1r B 2.20 BS01 III L 1 L178 S181 I182 H186 P199 I202 R261 R264 C274 G275 V276 Y278 S279 Y344 T347 G348 M351 K365 D368 V372 L144 S147 I148 H152 P165 I168 R227 R230 C240 G241 V242 Y244 S245 Y307 T310 G311 M314 K328 D331 V335 P21730 LEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFKSLPSLLRNVLTEES 6c1r B 2.20 BS02 EFD B 1 L211 A214 T215 S217 A218 F221 A242 V245 L249 L295 W299 P300 T303 L304 C307 L177 A180 T181 S183 A184 F187 A208 V211 L215 L261 W265 P266 T269 L270 C273 P21730 LEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFKSLPSLLRNVLTEES 6c28 A 2.09 BS01 WCA A 1 F63 F66 T76 P77 A78 S81 L101 G102 I103 N107 A110 M111 V152 F23 F26 T36 P37 A38 S41 L61 G62 I63 N67 A70 M71 V108 Q6N8V9 ELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSRSHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAREF 6c28 A 2.09 BS02 WCA D 1 L50 G52 Y53 K56 L60 N107 L10 G12 Y13 K16 L20 N67 Q6N8V9 ELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSRSHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAREF 6c28 B 2.09 BS01 WCA B 1 F63 F66 T76 P77 A78 S81 L101 I103 N107 F23 F26 T36 P37 A38 S41 L61 I63 N67 Q6N8V9 ELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSPHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAREF 6c28 C 2.09 BS01 WCA C 1 F63 F66 T76 P77 A78 S81 L101 G102 I103 N107 M111 F23 F26 T36 P37 A38 S41 L61 G62 I63 N67 M71 Q6N8V9 ELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAREF 6c28 D 2.09 BS01 WCA A 1 L50 G52 Y53 K56 L60 L10 G12 Y13 K16 L20 Q6N8V9 ELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAREF 6c2s A 2.85 BS01 NUC U 1 N93 Q94 T95 R105 P106 V109 R123 R131 S132 H133 N54 Q55 T56 R66 P67 V70 R84 R92 S93 H94 Q6N8V9 SELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSPSDRRSHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAR 6c2s A 2.85 BS02 NUC V 1 L104 P106 N107 D129 R130 R131 L65 P67 N68 D90 R91 R92 Q6N8V9 SELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSPSDRRSHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAR 6c2s B 2.85 BS01 NUC X 1 L104 P106 N107 R125 D129 R130 R131 L65 P67 N68 R86 D90 R91 R92 Q6N8V9 SELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSPSDRRSHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAR 6c2s D 2.85 BS01 NUC U 1 L104 P106 N107 S128 D129 R130 R131 L65 P67 N68 S89 D90 R91 R92 Q6N8V9 SELKMGELSELLGYALKRAQLRVFEDFLHCVAPVQLTPAQFSVLLLLDANPGRNQTEIATTLGILRPNFVAMLDALEGRGLCVRTRSPSDRRSHILMLTDKGRATLARAKKLVATRHEDRLTELLGRDNRDALLSMLATIAR 6c4u B 2.60 BS01 III H 1 R70 L82 P83 S85 N86 T106 N107 R133 R42 L54 P55 S57 N58 T78 N79 R105 29763736 GENIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEITVRTDPTGTILSLVIFINDKFKQSLE 6c4u C 2.60 BS01 III I 1 R70 N71 L82 P83 S85 N86 T106 N107 R133 P136 R40 N41 L52 P53 S55 N56 T76 N77 R103 P106 29763736 NIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEITVRTDPTGTILSLVIFINDKFKQSLEQ 6c4u D 2.60 BS01 III J 1 R70 N71 L82 P83 S85 N86 T106 N107 T134 P136 R41 N42 L53 P54 S56 N57 T77 N78 T105 P107 29763736 ENIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEITVRTDPTGTILSLVIFINDKFKQSL 6c4u E 2.60 BS01 III K 1 R70 N71 L82 P83 S85 N86 T106 N107 R133 R40 N41 L52 P53 S55 N56 T76 N77 R103 29763736 NIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEITVRTDPTGTILSLVIFINDKFKQSLEQ 6c4u A 2.60 BS01 III G 1 R70 L82 P83 S85 N86 T106 N107 R133 P136 R41 L53 P54 S56 N57 T77 N78 R104 P107 29763736 ENIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEITVRTDPTGTILSLVIFINDKFKQSLE 6c4u F 2.60 BS01 III L 1 R70 L82 S85 N86 T106 N107 R133 R40 L52 S55 N56 T76 N77 R103 29763736 NIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEITVRTDPTGTILSLVIFINDKFKQSLE 6c90 A 2.20 BS01 ADP A 1 F138 I139 D141 Q144 T163 S164 G166 K167 T168 N490 R527 F49 I50 D52 Q55 T74 S75 G77 K78 T79 N383 R420 3.6.4.13,3.6.4.13 P42285 LSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGSRTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 6c90 A 2.20 BS02 MG A 1 L573 L574 V576 I579 L466 L467 V469 I472 3.6.4.13,3.6.4.13 P42285 LSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGSRTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 6c98 A 1.85 BS01 CYS A 1 S37 P47 C48 S34 P44 C45 P55899 29782488 HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVEL 6c98 A 1.85 BS02 ER7 B 1 W29 P32 Q34 P228 S230 G232 W26 P29 Q31 P223 S225 G227 P55899 29782488 HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVEL 6c98 B 1.85 BS01 ER7 B 1 Y26 S52 D53 Y63 L64 L65 Y26 S52 D53 Y63 L64 L65 P61769 29782488 IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM 6c99 A 2.00 BS01 EQY A 1 W29 P32 Q34 G49 P228 S230 G232 W26 P29 Q31 G46 P225 S227 G229 P55899 29782488 HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELE 6c99 B 2.00 BS01 EQY A 1 S52 D53 Y63 L64 L65 Y67 S52 D53 Y63 L64 L65 Y67 P61769 29782488 IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM 6c99 C 2.00 BS01 EQY C 1 W29 P32 Q34 C48 G49 P228 S230 D231 G232 W26 P29 Q31 C45 G46 P220 S222 D223 G224 P55899 29782488 HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELE 6cdj A 1.13 BS01 GR8 A 1 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 I84 Q5RZ08 29763303 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 6cdj B 1.13 BS01 GR8 A 1 L23 D25 G27 A28 D29 D30 I47 G48 G49 P81 V82 I84 L23 D25 G27 A28 D29 D30 I47 G48 G49 P81 V82 I84 Q5RZ08 29763303 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 6cdl A 1.25 BS01 GR5 B 1 R8 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 P81 V82 I84 3.4.23.16 Q5RZ08 29763303 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 6cdl B 1.25 BS01 GR5 B 1 D25 G27 A28 D29 D30 I47 G48 G49 I50 V82 D25 G27 A28 D29 D30 I47 G48 G49 I50 V82 3.4.23.16 Q5RZ08 29763303 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 6cfc A 2.04 BS01 BLG A 1 E390 S399 V400 S401 A403 Q408 F409 M410 F412 L413 Y463 N464 G466 E498 E364 S373 V374 S375 A377 Q382 F383 M384 F386 L387 Y437 N438 G440 E472 A0A1L7J388 29758058 YSIEKLKKEENSLAKDYYIYRLLEKNKISKKDAQDLNSHIFRYIGKIKSELEKINPKYAKCYTYTANTILDANLTCQSVRLNSLVFIASLNSKDRTTLAQTFKNQRPDLTNLLLAFNTSDPMSYIVQKEDINGFFKLYNYSKKYDLDLNTSLVNKLPNHIGFKDFAQNIIIKKENPKFRHSMLEINPENVSEDSAFYLGVNALTYDKTELAYDFFKKAAQSFKSQSNKDNAIFWMWLIKNNEEDLKTLSQSSSLNIYSLYAKELTNTPFPKIESLNPSKKKNNFNMQDPFAWQKINKQIRDANASQLDVLAKEFDTQETLPIYAYILERKNNFKKHYFIMPYYDNIKDYNKTRQALILAIARQESRFIPTAISVSYALGMMQFMPFLANHIGEKELKIPNFDQDFMFKPEIAYYFGNYHLNYLESRLKSPLFVAYAYNGGIGFTNRMLARNDMFKTGKFEPFLSMELVPYQESRIYGKKVLANYIVYRHLLNDSIKISDIFENLIQ 6ci9 A 1.90 BS01 NAP A 1 G14 S16 K17 G18 I19 G38 R39 N40 A63 D64 V65 N91 G93 F95 T141 S142 S143 Y157 K161 P187 G188 N189 I190 T192 G194 L195 G16 S18 K19 G20 I21 G40 R41 N42 A65 D66 V67 N93 G95 F97 T143 S144 S145 Y159 K163 P189 G190 N191 I192 T194 G196 L197 1.1.1.100 A0QP46 29757625 SHMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPESHL 6ci9 A 1.90 BS02 F3V A 1 F95 S143 T145 W154 Y157 G188 N189 L195 Y202 F97 S145 T147 W156 Y159 G190 N191 L197 Y204 1.1.1.100 A0QP46 29757625 SHMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPESHL 6ci9 B 1.90 BS02 F3V B 1 F95 S143 T145 W154 Y157 G188 Y202 F96 S144 T146 W155 Y158 G189 Y203 1.1.1.100 A0QP46 29757625 HMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPESHL 6ci9 H 1.90 BS02 F3V H 1 F95 S143 T145 W154 Y157 G188 N189 Y202 F96 S144 T146 W155 Y158 G189 N190 Y203 1.1.1.100 A0QP46 29757625 HMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPES 6ci9 I 1.90 BS02 F3V I 1 F95 S143 T145 Y157 G188 N189 L195 Y202 F96 S144 T146 Y158 G189 N190 L196 Y203 1.1.1.100 A0QP46 29757625 HMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPESHLAIA 6ci9 K 1.90 BS02 F3V K 1 F95 S143 T145 W154 Y157 G188 L195 Y202 F97 S145 T147 W156 Y159 G190 L197 Y204 1.1.1.100 A0QP46 29757625 SHMFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPESH 6cq2 A 3.00 BS01 NUC B 1 E24 S25 P26 R46 G47 H48 D51 R54 A55 K89 D111 E115 R167 R168 D171 R172 G175 Y176 W183 K189 S191 A192 G193 R194 V195 Q196 Q332 Y342 R344 R533 S535 T536 R547 E9 S10 P11 R31 G32 H33 D36 R39 A40 K74 D96 E100 R152 R153 D156 R157 G160 Y161 W168 K174 S176 A177 G178 R179 V180 Q181 Q317 Y327 R329 R517 S519 T520 R531 5.99.1.2 P9WG49 SGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFAT 6cq2 A 3.00 BS02 MG A 1 E24 D111 E9 D96 5.99.1.2 P9WG49 SGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFAT 6cq2 A 3.00 BS03 MG A 2 E296 H492 E281 H476 5.99.1.2 P9WG49 SGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFAT 6cq2 A 3.00 BS04 MG A 3 D220 D507 H509 D205 D491 H493 5.99.1.2 P9WG49 SGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFAT 6cq2 A 3.00 BS05 MG A 4 E589 E598 H613 E573 E582 H597 5.99.1.2 P9WG49 SGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFAT 6csp A 1.24 BS02 FBM A 1 H573 H574 G582 F583 D612 H614 F643 D705 L712 Y745 H131 H132 G140 F141 D170 H172 F201 D263 L270 Y303 A7YT55 29775292 ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR 6csq A 2.03 BS02 F9P A 1 H573 H574 G582 F583 D612 H614 F643 D705 Y745 H131 H132 G140 F141 D170 H172 F201 D263 Y303 A7YT55 29775292 ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR 6cvm A 1.90 BS01 PTQ A 1 N102 V103 D201 H391 E461 M502 Y503 E537 H540 W568 D598 F601 V795 W999 N101 V102 D200 H390 E460 M501 Y502 E536 H539 W567 D597 F600 V794 W998 3.2.1.23 P00722 29754826 MITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFRVVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVVVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQ 6d6v A 4.80 BS01 NUC B 1 F178 Q181 N217 Q218 Y231 H234 M235 G236 R237 E238 F242 K243 S244 N324 Y325 L327 K328 K329 K332 L333 Y337 K341 K374 R413 L420 C424 Q444 K445 R446 K447 I449 S450 R453 R473 K497 K501 K532 R534 I545 T547 R550 N562 M566 R573 D589 N590 Q654 R655 N656 R658 N691 F692 F696 N697 K699 K762 N776 I909 K910 K913 K917 N918 R921 F924 I967 L969 K971 K973 Q974 Q978 Y979 D991 Y994 Y995 E998 S1026 K1038 K1041 Q1042 K1044 L1051 Q1052 K1053 R1055 K1056 S1057 F1059 F1060 Y1061 K1063 K1101 F167 Q170 N174 Q175 Y188 H191 M192 G193 R194 E195 F199 K200 S201 N237 Y238 L240 K241 K242 K245 L246 Y250 K254 K287 R326 L333 C337 Q357 K358 R359 K360 I362 S363 R366 R386 K410 K414 K430 R432 I443 T445 R448 N460 M464 R471 D487 N488 Q552 R553 N554 R556 N563 F564 F568 N569 K571 K634 N648 I781 K782 K785 K789 N790 R793 F796 I839 L841 K843 K845 Q846 Q850 Y851 D863 Y866 Y867 E870 S898 K910 K913 Q914 K916 L923 Q924 K925 R927 K928 S929 F931 F932 Y933 K935 K973 2.7.7.49 O77448 29775593 QMLTRKEDLLTVLKQISALKYVSNLYEFLLATEKIVQTSELDTQFQEFLTTTIIASEQNLVENYKQKYNQPNFSQLTIKQVIDDSIILLGNKQNYVQQIGTTTIGFYVEYENINLSRQTLYSSNFRNLLNIFGEEDFKYFLIDFLVFTKVEQNGYLQVAGVCLNQYFSVQKQENQYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVQSENKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEEFQKYPQGKLRIIPKKGSFRPIMTFLRKDKQKNIKLNLNQILMDSQLVFRNLKDMLGQKIGYSVFDNKQISEKFAQFIEKWKNKGRPQLYYVTLDIKKCYDSIDQMKLLNFFNQSDLIQDTYFINKYLLFQRNKRPLLQIQNFPYYFNLKERQIAYSLYDDDDQILQKGFKEIQSDDRPFIVINQDKPRCITKDIIHNHLKHISQYNVISFNKVKFRQKRGIPQGLNISGVLCSFYFGKLEEEYTQFLKNAEQVNGSINLLMRLTDDYLFISDSQQNALNLIVQLQNCANNNGFMFNDQKITTNFQFPQEDYNLEHFKISVQNECQWIGKSIDMNTLEIKSIQKQTQQEINQTINVAISIKNLKSQLKNKLRSLFLNQLIDYFNPNINSFEGLCRQLYHHSKATVMKFYPFMTKLFQIDLKKSKQYSVQYGKENTNENFLKDILYYTVEDVCKILCYLQFEDEINSNIKEIFKNLYSWIMWDIIVSYLKKKKQFKGYLNKLLQKIRKSRFFYLKEGCKSLQLILSQQKYQLNKKELEAIEFIDLNNLIQDIKTLIPKIS 6d6v A 4.80 BS02 NUC C 1 Q228 F414 H482 R543 I545 K555 N590 C622 Y623 Q773 T814 D815 D816 I877 G878 T902 N904 K919 S922 F924 L925 F960 Q185 F327 H395 R441 I443 K453 N488 C520 Y521 Q645 T686 D687 D688 I749 G750 T774 N776 K791 S794 F796 L797 F832 2.7.7.49 O77448 29775593 QMLTRKEDLLTVLKQISALKYVSNLYEFLLATEKIVQTSELDTQFQEFLTTTIIASEQNLVENYKQKYNQPNFSQLTIKQVIDDSIILLGNKQNYVQQIGTTTIGFYVEYENINLSRQTLYSSNFRNLLNIFGEEDFKYFLIDFLVFTKVEQNGYLQVAGVCLNQYFSVQKQENQYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVQSENKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEEFQKYPQGKLRIIPKKGSFRPIMTFLRKDKQKNIKLNLNQILMDSQLVFRNLKDMLGQKIGYSVFDNKQISEKFAQFIEKWKNKGRPQLYYVTLDIKKCYDSIDQMKLLNFFNQSDLIQDTYFINKYLLFQRNKRPLLQIQNFPYYFNLKERQIAYSLYDDDDQILQKGFKEIQSDDRPFIVINQDKPRCITKDIIHNHLKHISQYNVISFNKVKFRQKRGIPQGLNISGVLCSFYFGKLEEEYTQFLKNAEQVNGSINLLMRLTDDYLFISDSQQNALNLIVQLQNCANNNGFMFNDQKITTNFQFPQEDYNLEHFKISVQNECQWIGKSIDMNTLEIKSIQKQTQQEINQTINVAISIKNLKSQLKNKLRSLFLNQLIDYFNPNINSFEGLCRQLYHHSKATVMKFYPFMTKLFQIDLKKSKQYSVQYGKENTNENFLKDILYYTVEDVCKILCYLQFEDEINSNIKEIFKNLYSWIMWDIIVSYLKKKKQFKGYLNKLLQKIRKSRFFYLKEGCKSLQLILSQQKYQLNKKELEAIEFIDLNNLIQDIKTLIPKIS 6d6v D 4.80 BS01 NUC B 1 Y565 H566 G567 D568 Y55 H56 G57 D58 D2CVN6 29775593 QRIYSSIEEIIQQAQASEIGQKKEFYVYGNLVSIQMKNKLYYYRCTCQGKSVLKYHGDSFFCESCQQFINPQVHLMLRAFVQDSTGTIPVMIFDQQSSQLINQIDPSIHVQEAGQYVKNCIENGQEEIIRQLFSKLDFARFIFEIQFENKEFNNEQEIAYKVLKIEKENIKEESKYLLKKLEHLI 6d6v D 4.80 BS02 NUC C 1 R554 Q558 G559 K560 S561 V562 K564 Y565 H566 S569 E573 S574 R588 M601 F603 K660 R44 Q48 G49 K50 S51 V52 K54 Y55 H56 S59 E63 S64 R78 M91 F93 K150 D2CVN6 29775593 QRIYSSIEEIIQQAQASEIGQKKEFYVYGNLVSIQMKNKLYYYRCTCQGKSVLKYHGDSFFCESCQQFINPQVHLMLRAFVQDSTGTIPVMIFDQQSSQLINQIDPSIHVQEAGQYVKNCIENGQEEIIRQLFSKLDFARFIFEIQFENKEFNNEQEIAYKVLKIEKENIKEESKYLLKKLEHLI 6d6v D 4.80 BS03 ZN D 1 C555 C572 C575 C45 C62 C65 D2CVN6 29775593 QRIYSSIEEIIQQAQASEIGQKKEFYVYGNLVSIQMKNKLYYYRCTCQGKSVLKYHGDSFFCESCQQFINPQVHLMLRAFVQDSTGTIPVMIFDQQSSQLINQIDPSIHVQEAGQYVKNCIENGQEEIIRQLFSKLDFARFIFEIQFENKEFNNEQEIAYKVLKIEKENIKEESKYLLKKLEHLI 6d6v H 4.80 BS01 NUC B 1 K392 A393 V396 R400 Y407 I514 F516 K517 K518 N519 E520 F521 R522 F526 K528 K15 A16 V19 R23 Y30 I90 F92 K93 K94 N95 E96 F97 R98 F102 K104 Q6JXI6 29775593 NCLIKIINIPQGTLKAEVVLAVRHLGYEFYCDYIDGQAMIRFQNSDEQRLAIQKLLNHNNNKLQIEIRGQICDVISTIPEDEEKNYWNYIKFKKNEFRKFFFMKKQQK 6d8d A 3.55 BS01 SIA A 1 Y88 V125 T126 S127 W142 L144 H174 V177 E181 L185 L217 Y88 V125 T126 S127 W142 L144 H174 V177 E181 L185 L217 A0A2I7YV81 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKETMGFTYNGIRTNGVTSACKRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPAIIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLILNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 6d8d A 3.55 BS02 GAL A 1 E181 K184 E181 K184 A0A2I7YV81 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKETMGFTYNGIRTNGVTSACKRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPAIIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLILNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 6dco A 2.20 BS01 III C 1 A93 E96 F97 R100 Y101 F105 L108 L112 S122 Q125 V126 E129 L130 D133 N136 G138 R139 F146 L194 Y195 A41 E44 F45 R48 Y49 F53 L56 L60 S70 Q73 V74 E77 L78 D81 N84 G86 R87 F94 L142 Y143 Q07817 PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN 6dco B 2.20 BS01 III D 1 A93 E96 F97 Y101 F105 L108 V126 E129 L130 D133 N136 G138 R139 A142 F146 Y195 A41 E44 F45 Y49 F53 L56 V74 E77 L78 D81 N84 G86 R87 A90 F94 Y143 Q07817 PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNN 6ei5 A 2.20 BS01 B5Q A 1 N51 A55 D93 I96 G97 M98 D102 N106 L107 F138 Y139 W162 T184 N37 A41 D79 I82 G83 M84 D88 N92 L93 F124 Y125 W148 T170 P07900 29768913 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6el5 A 1.67 BS01 PU1 A 1 N51 A55 D93 I96 G97 M98 L103 L107 G135 F138 V150 W162 T184 N36 A40 D78 I81 G82 M83 L88 L92 G120 F123 V135 W147 T169 P07900 29768913 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6elo A 1.80 BS01 BAW A 1 N51 S52 A55 K58 D93 I96 G97 M98 L107 G108 F138 V150 T184 V186 N35 S36 A39 K42 D77 I80 G81 M82 L91 G92 F122 V134 T168 V170 P07900 29768913 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6elp A 1.85 BS01 BA8 A 1 N51 D54 A55 D93 I96 G97 M98 L107 F138 Y139 W162 T184 V186 N35 D38 A39 D77 I80 G81 M82 L91 F122 Y123 W146 T168 V170 P07900 29768913 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6ey9 A 2.00 BS01 C4N A 1 N51 A55 D93 I96 G97 M98 L103 N106 F138 V150 W162 T184 V186 N36 A40 D78 I81 G82 M83 L88 N91 F123 V135 W147 T168 V170 P07900 29768913 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6eya A 2.10 BS01 C4K A 1 N51 D54 A55 D93 I96 M98 L103 N106 F138 V150 W162 T184 V186 N35 D38 A39 D77 I80 M82 L87 N90 F118 V130 W142 T164 V166 P07900 29768913 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6eyb A 1.90 BS01 C3Z A 1 N51 A55 D93 I96 G97 M98 L103 L107 F138 V150 T184 V186 N35 A39 D77 I80 G81 M82 L87 L91 F122 V134 T168 V170 P07900 29768913 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6f1n A 2.09 BS01 C8W A 1 N51 A55 D93 I96 G97 M98 N106 L107 T109 G135 F138 Y139 T184 N37 A41 D79 I82 G83 M84 N92 L93 T95 G121 F124 Y125 T170 P07900 29768913 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVE 6f7w A 1.28 BS01 QQ7 A 1 K34 G35 W36 Y37 K34 G35 W36 Y37 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 6f7x A 2.42 BS02 MFU A 2 R17 E28 G39 A40 F41 I61 W76 W81 R17 E28 G39 A40 F41 I61 W76 W81 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTATN 6f7x A 2.42 BS03 QQ7 A 1 D32 K34 G35 Y37 D32 K34 G35 Y37 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTATN 6f7x B 2.42 BS01 MFU B 2 R17 E28 C30 G39 A40 I59 I61 W76 W81 R17 E28 C30 G39 A40 I59 I61 W76 W81 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTATN 6f7x B 2.42 BS02 MFU B 1 W53 R62 E73 G84 A85 Y86 W53 R62 E73 G84 A85 Y86 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTATN 6f7x B 2.42 BS03 QQ7 B 1 K34 Y37 K34 Y37 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTATN 6f7x C 2.42 BS03 MFU C 2 R17 E28 C30 G39 A40 F41 W76 W81 R17 E28 C30 G39 A40 F41 W76 W81 A0A0S4TLR1 29673020 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTATN 6fg6 A 2.40 BS01 D8Q A 1 P1817 F1818 V1822 Y1830 N1873 V1879 P22 F23 V27 Y35 N78 V84 Q9UIF9 29770599 HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY 6fgf A 2.80 BS01 EN2 A 1 P1817 F1818 V1822 L1826 Y1830 F1872 N1873 V1879 P22 F23 V27 L31 Y35 F77 N78 V84 Q9UIF9 29770599 HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY 6fgg A 1.10 BS01 D9B A 1 W1816 P1817 F1818 V1822 Y1830 F1872 N1873 V1879 W18 P19 F20 V24 Y32 F74 N75 V81 Q9UIF9 29770599 LTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQ 6fgh A 2.10 BS01 6RZ A 1 P1817 V1822 N1823 V1827 Y1830 F1872 N1873 P22 V27 N28 V32 Y35 F77 N78 Q9UIF9 29770599 HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY 6fgl A 2.10 BS01 UO1 A 1 W1816 P1817 E1820 P1821 V1822 N1823 L1826 V1827 F1872 N1873 V1879 W21 P22 E25 P26 V27 N28 L31 V32 F77 N78 V84 Q9UIF9 29770599 HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY 6fgn A BS01 ZN A 1 H22 C26 C31 C36 H22 C26 C31 C36 2.3.1.48,2.3.1.- Q9H3D4 ATQSPGDSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALAAYHAKHCQENKCPVPFCLNIKQKGTIEGRGNEFLSPEVFQHIWDFLEQPISSVQPID 6fgs A BS01 ZN A 1 H22 C26 C31 C36 H22 C26 C31 C36 2.3.1.48,2.3.1.- O15350 ATQSPGDSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALAAYHAKHCQENKCPVPFCLNIKQKGGSGGGTGGGSGTIEGRGDGGTTFEHLWSSLEPDSTYFDL 6fgu A 2.05 BS01 D9Q A 1 P1888 F1889 V1893 Y1901 N1944 I1950 P33 F34 V38 Y46 N89 I95 Q9UIF8 29770599 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFKV 6fgv A 2.50 BS01 D9T A 1 P1817 F1818 V1822 Y1830 F1872 N1873 V1879 P22 F23 V27 Y35 F77 N78 V84 Q9UIF9 29770599 HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY 6fh6 A 2.08 BS01 D8Q A 1 P1888 F1889 Y1901 F1943 N1944 I1950 P33 F34 Y46 F88 N89 I95 Q9UIF8 29770599 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFK 6fh7 A 2.10 BS01 EN2 A 1 W1887 P1888 F1889 L1891 V1893 N1944 I1950 W32 P33 F34 L36 V38 N89 I95 Q9UIF8 29770599 SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTFKV 6fii B 2.41 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G142 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G140 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 6fii D 2.41 BS02 SG9 D 1 S174 P175 S178 D179 T180 V181 E183 P184 Q394 A397 M398 F404 S172 P173 S176 D177 T178 V179 E181 P182 Q376 A379 M380 F386 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6fii F 2.41 BS01 ACP F 1 K74 P95 I148 K150 I160 Q183 K184 Y185 L186 K198 D200 L240 T241 N242 D318 M320 I330 E331 N333 K74 P95 I126 K128 I138 Q161 K162 Y163 L164 K176 D178 L218 T219 N220 D296 M298 I308 E309 N311 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIAKSSAGAKGEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLAPTSIFIKLH 6fjf D 2.40 BS01 GDP D 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V171 V177 D179 E183 N206 L209 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 V169 V175 D177 E181 N204 L207 Y222 N226 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6fjf D 2.40 BS03 DKE D 1 G100 N102 K105 T180 V181 V182 R401 F404 W407 Y408 G98 N100 K103 T178 V179 V180 R382 F385 W388 Y389 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6fjf F 2.40 BS01 ACP F 1 K74 I148 K150 Q183 K184 Y185 L186 K198 D200 R202 T241 N242 D318 M320 E331 N333 K74 I126 K128 Q157 K158 Y159 L160 K172 D174 R176 T215 N216 D292 M294 E305 N307 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIAKSSGEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLAPTSIFIKLH 6fjm D 2.10 BS02 DKN D 1 G100 N101 N102 D179 T180 V181 V182 F404 W407 Y408 G97 N98 N99 D176 T177 V178 V179 F388 W391 Y392 Q6B856 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6fjm D 2.10 BS03 CA D 1 R308 N339 R300 N331 Q6B856 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6fjm D 2.10 BS04 CA D 2 P222 Y224 P219 Y221 Q6B856 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6fjm F 2.10 BS01 ACP F 1 K74 I148 K150 Q183 K184 Y185 L186 K198 D200 R202 R222 L240 T241 N242 D318 I330 E331 N333 K74 I126 K128 Q161 K162 Y163 L164 K176 D178 R180 R200 L218 T219 N220 D296 I308 E309 N311 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIAKSSAGAKGEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 6fm7 A 1.04 BS01 NXL A 1 S62 Q118 Y148 N150 T313 G314 S315 I343 S59 Q115 Y145 N147 T310 G311 S312 I340 3.5.2.6 B2BSN6 29786960 EPMANIVEKAVQPLLEEYRIPGMAVAVLKEGKPHYFNYGVANRESGRRISERTLFEIGSVSKTFTATLGTYAVVKGGFRLDDKVSQHAPWLQNSAFDRVTMAQLATYSAGGLPLQFPDAVDSNERMRQYYRQWSPLYAAGTHREYSNPSIGLFGHLAASTLGQPFRQLMSQTLLPKLDLQHTYLEVPDAAMVDYAYGYSKEDKPVRVNPGVLADEAYGIKTSAADLIKFVGANMTGSGDKAVQQALAMTRTGFYSVGEMTQGLGWESYAYPVTEQALLAGNSPAVSFKANPVKPFVAPRVMGNERLYNKTGSTNGFGAYVVFVPARGVGIVMLANRNYPIEARVKAAYAIMRHLAP 6fpc A 1.75 BS01 ZN A 1 H137 H141 Y174 E181 H107 H111 Y144 E151 K4ZRC1 SILDKLVVLPSGEYNHSEAAAMKQRLEKIPTSILDALYSKGVKIKLTQGAITNEPELAYLKGVVPRGWEGTGLTWDDVPGVSERVVAVRIGYSEKGKGHNSLNLEIHETLHAVDRLVLNEVSGTDEFINIFNKEASVKYKGDGYVSAYPTEYFAEAASLYLYSDATRSDLKDSMPLTYEFMAKLF 6fpc D 1.75 BS01 ZN D 1 H137 H141 E181 H91 H95 E135 K4ZRC1 QSILDKLVVLPSGEYNHSEAAAMKQRLEKIPTSILDALYSKGVKIKLTQGAITNEPELAYLKGVVPERVVAVRIGYSEKGKGHNSLNLEIHETLHAVDRLVLNEVSGTDEFINIFNKEASVKYKGDGYVSAYPTEYFAEAASLYLYSDATRSDLKDSMPLTYEFMAKLF 6g0c A 2.80 BS01 1PS A 1 D389 W394 N404 Q405 W432 D168 W173 N183 Q184 W210 3.4.22.-,2.3.2.-,2.4.2.31 Q5ZTK4 QDKSVPVWNGFSLYTDDTVKAAAQYAYDNYLGKPYTGSVESAPANFGGRMVYRQHHGLSHTLRTMAYAELIVEEARKAKLRGETLGKFKDGRTIADVTPQELKKIMIAQAFFVAGRDDEASDAKNYQKYHEQSRDAFLKYVKDNESTLIPDVFKDQEDVNFYARVIEDKSHDWESTPAHVLINQGHMVDLVRVKPPESFLQRYFSSMQRWIGSQATEAVFGIQRQFFHATYEVVAGFDSDNKEPHLVVSGLGRYVIGAPKKGQKEGDLKVFPQTYERLMRVDEFLKLPEIQNTFPGSGKHLQGGMPGMNEMDYWNRLNSLNRARCENDVDFCLKQLQTAHDKAKIEPIKQAFQSSKGKERRQPNVDEIAAARIIQQILANPDCIHDDHVLINGQKLEQQFFRDLLAKCEMAVVGSLLNDTDIGNIDTLMRHEKDTEFHSTNPEAVPVKIGEYWINDQRIITQKKHDLIFLMQNDAWYFSRVNAIAQNRDKGSTFKEVLITTLMTPLTSKALVDTSQPPTRLFRGLNLSEEFTKGLIDQANAMIANTTERLFTDNASTTTEIKLVKETWDSNVIFEMLDPDGLLHEFSVYLPEDVALVPVKVTLDGKTQKGENRYVFTFVAVKSP 6g58 A 1.90 BS01 EOW A 1 K39 Y43 L85 K131 R138 H168 N203 S204 R219 G221 I222 Y354 K39 Y43 L85 K131 R138 H168 N203 S204 R219 G221 I222 Y354 5.1.1.1 P63479 FSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK 6g59 A 2.45 BS01 EM2 A 1 K39 Y43 L85 F166 H168 N203 S204 R219 G221 I222 Y354 K44 Y48 L90 F171 H173 N208 S209 R224 G226 I227 Y359 5.1.1.1 P63479 YKKAGFSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK 6g8x A 1.76 BS01 EQT A 1 A35 I56 Y64 R67 T68 E71 D167 G169 L170 A25 I46 Y54 R57 T58 E61 D157 G159 L160 2.7.11.24 P28482 29775310 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFLPKEKLKELIFEETARFQPG 6g8x A 1.76 BS02 EQT A 2 A52 Q105 D106 L107 M108 L156 A42 Q95 D96 L97 M98 L146 2.7.11.24 P28482 29775310 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFLPKEKLKELIFEETARFQPG 6g91 A 1.80 BS01 EQW A 1 A52 Q105 D106 M108 E109 T110 D111 K114 L156 A45 Q98 D99 M101 E102 T103 D104 K107 L149 2.7.11.24 P28482 29775310 GAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFLDDLPKEKLKELIFEETARFQPG 6g92 A 1.99 BS01 ERZ A 1 I31 A52 Q105 D106 M108 E109 T110 K114 L156 I24 A45 Q98 D99 M101 E102 T103 K107 L149 2.7.11.24 P28482 29775310 GAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFDDLPKEKLKELIFEETARFQPG 6g93 A 1.67 BS01 EU2 A 1 I31 A52 K54 Q105 D106 M108 E109 T110 D111 K114 L156 D167 I21 A42 K44 Q95 D96 M98 E99 T100 D101 K104 L146 D157 2.7.11.24 P28482 29775310 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFLDDLPKEKLKELIFEETARFQPG 6g97 A 1.90 BS01 EQZ A 1 I31 E33 G34 G37 V39 A52 K54 Q105 D106 L107 M108 E109 T110 D111 K114 L156 C166 D167 I21 E23 G24 G27 V29 A42 K44 Q95 D96 L97 M98 E99 T100 D101 K104 L146 C156 D157 2.7.11.24 P28482 29775310 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFELDDLPKEKLKELIFEETARFQPG 6g9a A 1.91 BS01 ESQ A 1 G32 E33 G34 G37 V39 A52 K54 Q105 D106 M108 E109 T110 D111 K114 S153 N154 L156 C166 D167 G25 E26 G27 G30 V32 A45 K47 Q98 D99 M101 E102 T103 D104 K107 S146 N147 L149 C159 D160 2.7.11.24 P28482 29775310 GAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFLPKEKLKELIFEETARFQPG 6g9d A 1.80 BS01 ER8 A 1 I31 Y36 V39 A52 K54 I56 R67 E71 Q105 D106 M108 T110 D111 K114 L156 D167 G169 I24 Y29 V32 A45 K47 I49 R60 E64 Q98 D99 M101 T103 D104 K107 L149 D160 G162 2.7.11.24 P28482 29775310 GAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFELDDLPKEKLKELIFEETARFQPG 6g9h A 1.73 BS01 ERW A 1 I31 Y36 A52 K54 I56 R67 E71 Q105 D106 M108 E109 T110 D111 K114 L156 D167 I21 Y26 A42 K44 I46 R57 E61 Q95 D96 M98 E99 T100 D101 K104 L146 D157 2.7.11.24 P28482 29775310 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFLDDLPKEKLKELIFEETARFQPG 6g9j A 1.98 BS01 ERK A 1 I31 Y36 V39 A52 K54 I56 Y64 R67 T68 E71 Q105 D106 M108 E109 T110 D111 K114 L156 C166 D167 G169 I24 Y29 V32 A45 K47 I49 Y57 R60 T61 E64 Q98 D99 M101 E102 T103 D104 K107 L149 C159 D160 G162 2.7.11.24 P28482 29775310 GAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 6g9m A 1.86 BS01 ESW A 1 I31 G34 A35 G37 V39 A52 K54 I56 Q105 D106 M108 E109 T110 D111 K114 L156 C166 D167 I21 G24 A25 G27 V29 A42 K44 I46 Q95 D96 M98 E99 T100 D101 K104 L146 C156 D157 2.7.11.24 P28482 29775310 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFELDDLPKEKLKELIFEETARFQP 6gdm A 1.91 BS01 F3Z A 1 I31 A35 Y36 A52 K54 I56 Y64 R67 T68 E71 Q105 D106 L107 M108 E109 L156 C166 D167 G169 I24 A28 Y29 A45 K47 I49 Y57 R60 T61 E64 Q98 D99 L100 M101 E102 L149 C159 D160 G162 2.7.11.24 P28482 29775310 GAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDDLPKEKLKELIFEETARFQP 6gdq A 1.86 BS01 EVK A 1 I31 E33 G34 Y36 G37 M38 V39 A52 K54 I84 Q105 D106 M108 E109 T110 N154 L156 C166 D167 I22 E24 G25 Y27 G28 M29 V30 A43 K45 I75 Q96 D97 M99 E100 T101 N145 L147 C157 D158 2.7.11.24 P28482 29775310 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKPKEKLKELIFEETARFQPG 6gii A 1.90 BS01 HEM A 1 F114 L151 V152 H159 R163 F170 I305 A308 A309 T312 T313 A316 L349 P354 V355 W358 R360 N411 F412 G413 Y414 H417 Q418 C419 L420 G421 L424 G425 E428 F53 L90 V91 H98 R102 F109 I244 A247 A248 T251 T252 A255 L288 P293 V294 W297 R299 N350 F351 G352 Y353 H356 Q357 C358 L359 G360 L363 G364 E367 A0A0K6ITW2 29738765 VHRLAEDFDPFQDAYMADPAQFVRWAREQVPIFYAPKLNYWVVTRYDTIKQIFRDPVTFSPSNVLQSFAQPSAEVRQVLERYGYAFNRTLVNEDEPMHLERRRVLMEPFASEHLAEHEPMVRELVRRAVNRFIDTGRADLVDQMIWEVPFTVALHFLGVDDDDREKMRRFAIAHTVNAFGRPSPEEQLAVAETVGQFWQFCGEVLEKMRRTADGPGWMRYSIRQQKLYPDVVTDSYLHSMMQAIIVAAHETTVFATTNALKTLLEHETVWREICADPSLIPAAAEECLRYNGPVAGWRRRTTREVEVEGVRLPVGANILMVVASANHDSAHFDDPEFFDIGRSNASEHLNFGYGAHQCLGRNLGRMEMQIMIEELSRRLPHMRLAEQRFDYLHNVSFRAPRHLWVEWDPAQNPERR 6gis A 2.82 BS01 NUC D 1 D21 K77 R149 H153 K217 D21 K77 R149 H153 K211 P12004 28071730 MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPK