5kdb A 1.64 BS01 HEM A 1 I97 L98 H105 R109 L112 L116 F160 S244 L245 A248 G249 T252 T253 V289 P294 V295 F298 R300 L323 V349 G350 F351 G352 H356 M357 C358 V359 G360 V363 A364 I81 L82 H89 R93 L96 L100 F144 S228 L229 A232 G233 T236 T237 V273 P278 V279 F282 R284 L307 V333 G334 F335 G336 H340 M341 C342 V343 G344 V347 A348 Q2IU02 TIPHLAIDPFSLDFFDDPYPDQQTLRDAGPVVYLDKWNVYGVARYAEVHAVLNDPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLSPATMKTIRDGFAAAADAKVDELLQRGCIDAIADLAEAYPLSVFPDAMGLKQEGREHLLPYAGLVFNAFGPPNELRQTAIERSAPHQAYVNEQCQRPNLAPGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLDTTVNGIGAAVYCLARFPGELQRLRSDPTLARNAFEEAVRFESPVQTFFRTTTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDPDLYDITRKTSGHVGFGSGVHMCVGQLVARLEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPVKLTPA 5kdb A 1.64 BS02 4IA A 1 R92 S95 L98 F182 S244 S247 A248 T252 F298 R76 S79 L82 F166 S228 S231 A232 T236 F282 Q2IU02 TIPHLAIDPFSLDFFDDPYPDQQTLRDAGPVVYLDKWNVYGVARYAEVHAVLNDPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLSPATMKTIRDGFAAAADAKVDELLQRGCIDAIADLAEAYPLSVFPDAMGLKQEGREHLLPYAGLVFNAFGPPNELRQTAIERSAPHQAYVNEQCQRPNLAPGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLDTTVNGIGAAVYCLARFPGELQRLRSDPTLARNAFEEAVRFESPVQTFFRTTTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDPDLYDITRKTSGHVGFGSGVHMCVGQLVARLEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPVKLTPA 5kdy A 1.59 BS01 HEM A 1 I97 L98 H105 R109 F160 A248 G249 T252 T253 V295 F298 R300 L323 G350 F351 G352 H356 C358 V359 G360 A364 I81 L82 H89 R93 F144 A232 G233 T236 T237 V279 F282 R284 L307 G334 F335 G336 H340 C342 V343 G344 A348 Q2IU02 TIPHLAIDPFSLDFFDDPYPDQQTLRDAGPVVYLDKWNVYGVARYAEVHAVLNDPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLSPATMKTIRDGFAAAADAKVDELLQRGCIDAIADLAEAYPLSVFPDAMGLKQEGREHLLPYAGLVFNAFGPPNELRQTAIERSAPHQAYVNEQCQRPNLAPGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLNTTVNGIGAAVYCLARFPGELQRLRSDPTLARNAFEEAVRFESPVQTFFRTTTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDPDLYDITRKTSGHVGFGSGVHMCVGQLVARLEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPVKLTPA 5kdy A 1.59 BS02 ANN A 1 R92 S95 I97 L98 F182 S244 S247 A248 F298 R76 S79 I81 L82 F166 S228 S231 A232 F282 Q2IU02 TIPHLAIDPFSLDFFDDPYPDQQTLRDAGPVVYLDKWNVYGVARYAEVHAVLNDPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLSPATMKTIRDGFAAAADAKVDELLQRGCIDAIADLAEAYPLSVFPDAMGLKQEGREHLLPYAGLVFNAFGPPNELRQTAIERSAPHQAYVNEQCQRPNLAPGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLNTTVNGIGAAVYCLARFPGELQRLRSDPTLARNAFEEAVRFESPVQTFFRTTTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDPDLYDITRKTSGHVGFGSGVHMCVGQLVARLEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPVKLTPA 5kdz A 1.42 BS02 HEM A 1 I97 L98 H105 R109 L116 F160 L245 A248 G249 A252 T253 V295 F298 R300 L323 G350 F351 G352 H356 C358 V359 G360 A364 I81 L82 H89 R93 L100 F144 L229 A232 G233 A236 T237 V279 F282 R284 L307 G334 F335 G336 H340 C342 V343 G344 A348 Q2IU02 TIPHLAIDPFSLDFFDDPYPDQQTLRDAGPVVYLDKWNVYGVARYAEVHAVLNDPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLSPATMKTIRDGFAAAADAKVDELLQRGCIDAIADLAEAYPLSVFPDAMGLKQEGREHLLPYAGLVFNAFGPPNELRQTAIERSAPHQAYVNEQCQRPNLAPGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLDATVNGIGAAVYCLARFPGELQRLRSDPTLARNAFEEAVRFESPVQTFFRTTTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDPDLYDITRKTSGHVGFGSGVHMCVGQLVARLEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPVKLTPA 5nf2 A 1.73 BS01 CA A 1 D507 D509 N512 P513 E514 D429 D431 N434 P435 E436 B2RHG1 29379120 PGEWAGKDKIEKVSIYMVPQGGPGLVESAEDLDFGTYYENPTIDPATHNAILKPKKGIKVNSAVGKTVKVYVVLNDIAGKAKALLANVNAADFDAKFKEIIELSTQAQALGTVADGPNPATAAGKIAKKNGTTDETIMMTCLQPSDALTIEAKVTVERSVARAMVSTKAQSYEIKATTQIGEIAAGSVLATITDIRWVVAQGERRQYLSKKRGTVPENTWVTPGSGFVPTSSTFHTNATEYYDYAGLWEDHNTNEAVISGTQVPTLADYQLQDVTGELANALSGKFLLPNTHKSGANAASSDYKRGNTAYVLVRAKFTPKKEAFIDRGKTYSDNTAVPEYVAGEDFFVGENGQFYVSMKSVTDPKVGGVAGMKAHKYVKGKVLYYAWLNPSTTSPDSWWNSPVVRNNIYHIHIKSIKKLGFNWNPLVPDPDPSNPENPNNPDPNPDEPGTPVPTDPENPLPDQDTFMSVEVTVLPWKVHSYEVDL 5o3u A 1.86 BS01 III L 1 F86 S133 L134 Y135 F178 S179 P180 C259 T394 Y481 F484 I486 G561 A562 N563 N585 L602 W603 R655 H695 F86 S133 L134 Y135 F178 S179 P180 C250 T381 Y468 F471 I473 G548 A549 N550 N572 L589 W590 R642 H682 R4P353 29377663 MATSGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3u A 1.86 BS02 III L 2 I73 V77 R81 F95 N97 A102 Q103 N104 L132 F492 S493 A494 S495 T700 V707 I73 V77 R81 F95 N97 A102 Q103 N104 L132 F479 S480 A481 S482 T687 V694 R4P353 29377663 MATSGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3u B 1.86 BS02 III M 2 R81 F95 N97 A102 Q103 N104 L132 F492 S493 A494 S495 T700 V707 R77 F91 N93 A98 Q99 N100 L128 F471 S472 A473 S474 T679 V686 R4P353 29377663 GFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3u C 1.86 BS01 III N 1 F86 S133 L134 Y135 F178 P180 C259 Y481 F484 I486 G561 A562 N563 N585 L602 W603 R655 H695 F82 S129 L130 Y131 F174 P176 C244 Y463 F466 I468 G543 A544 N545 N567 L584 W585 R637 H677 R4P353 29377663 GFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRDSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3v A 2.17 BS01 III C 1 F178 G258 C259 Y481 G561 A562 N563 W603 R655 H695 Y696 F175 G255 C256 Y473 G553 A554 N555 W595 R647 H687 Y688 R4P353 29377663 SGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3v A 2.17 BS02 III C 2 V77 R81 F95 N97 A102 N104 L132 F492 S493 A494 S495 Y696 T700 V707 V74 R78 F92 N94 A99 N101 L129 F484 S485 A486 S487 Y688 T692 V699 R4P353 29377663 SGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3v B 2.17 BS01 III D 1 F178 K241 C259 Y481 I486 G561 A562 N563 N585 W603 R655 H695 Y696 F175 K238 C256 Y473 I478 G553 A554 N555 N577 W595 R647 H687 Y688 R4P353 29377663 SGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3w A 2.00 BS01 III W 1 R81 G83 F86 F95 N104 Y135 S493 A494 S495 V707 R78 G80 F83 F92 N101 Y126 S484 A485 S486 V692 R4P353 29377663 SGFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRGREDSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKATMTQIAEVADRYGFMAKALEAPWID 5o3w B 2.00 BS01 III X 1 R81 F95 N97 A102 N104 L132 S493 A494 S495 R698 T700 V707 R76 F90 N92 A97 N99 L127 S486 A487 S488 R691 T693 V700 R4P353 29377663 FSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRGDSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3w C 2.00 BS01 III Y 1 R81 F95 N97 A102 N104 L132 S493 A494 S495 T700 I704 V707 R76 F90 N92 A97 N99 L127 S485 A486 S487 T692 I696 V699 R4P353 29377663 FSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRGSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKALEAPWID 5o3w D 2.00 BS01 III Z 1 R81 G83 V84 F86 F95 N104 D391 G392 F492 S493 A494 S495 V707 R76 G78 V79 F81 F90 N99 D375 G376 F476 S477 A478 S479 V685 R4P353 29377663 FSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEKLANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQNVFQMQDDKPEVLYDPNSGLSLYSVSEDAKYFAFGIHSGLTEWVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPLKEGEDHMTRSAVNQEARYHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKVYCLDLTKLPNGLESFRGDSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDAPRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHVLEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQCDLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQHVLCTSLEDSPQKNPIIARIQRKATMTQIAEVADRYGFMAKALEAPWID 5o49 A 1.91 BS01 9K5 A 1 L484 G485 E486 G487 F489 G490 V492 A512 K514 V561 E562 Y563 A564 L630 D641 L21 G22 E23 G24 F26 G27 V29 A49 K51 V98 E99 Y100 A101 L155 D166 2.7.10.1 P11362 29119993 ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ 5o49 B 1.91 BS01 9K5 B 1 L484 G485 E486 F489 V492 A512 K514 V561 E562 Y563 A564 L630 L25 G26 E27 F30 V33 A50 K52 V99 E100 Y101 A102 L156 2.7.10.1 P11362 29119993 VSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 5o4a A 2.01 BS01 9K8 A 1 L484 G485 E486 F489 G490 A512 K514 E562 Y563 A564 L630 D641 L21 G22 E23 F26 G27 A49 K51 E99 Y100 A101 L156 D167 2.7.10.1 P11362 29119993 ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ 5o4a B 2.01 BS01 9K8 B 1 L484 G485 E486 G490 Q491 V492 A512 K514 E562 Y563 A564 L630 D641 L25 G26 E27 G31 Q32 V33 A51 K53 E101 Y102 A103 L163 D174 2.7.10.1 P11362 29119993 VSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYSYEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSN 5ow7 A 2.10 BS01 III B 1 I270 K274 R280 Q287 I288 L291 K292 P442 L443 E446 E451 V452 S453 I57 K61 R67 Q74 I75 L78 K79 P229 L230 E233 E238 V239 S240 Q9PTN2 29367669 HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS 5ow7 A 2.10 BS02 AYK A 1 Y175 Y179 L255 L258 L261 V262 S265 I299 S303 S306 W314 C316 V328 A331 H333 L337 H423 Y22 Y26 L42 L45 L48 V49 S52 I86 S90 S93 W101 C103 V115 A118 H120 L124 H210 Q9PTN2 29367669 HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS 5ow9 A 2.40 BS01 III B 1 I270 K274 R280 Q287 I288 L291 K292 P442 L443 E446 E451 I57 K61 R67 Q74 I75 L78 K79 P229 L230 E233 E238 Q9PTN2 29367669 HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV 5ow9 A 2.40 BS02 AYT A 1 Y175 Y179 L258 A259 L261 V262 S265 I299 S303 S306 W314 C316 V328 H333 H423 Y427 L430 Y22 Y26 L45 A46 L48 V49 S52 I86 S90 S93 W101 C103 V115 H120 H210 Y214 L217 Q9PTN2 29367669 HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV 5owd A 2.15 BS01 III B 1 I270 K274 Q287 I288 L291 K292 P442 L443 E446 E451 S453 I55 K59 Q72 I73 L76 K77 P227 L228 E231 E236 S238 Q9PTN2 29367669 MLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS 5owd A 2.15 BS02 B0B A 1 Y175 Y179 L255 L258 L261 V262 I299 S303 S306 W314 C316 V328 H333 Y21 Y25 L40 L43 L46 V47 I84 S88 S91 W99 C101 V113 H118 Q9PTN2 29367669 MLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS 5oyd A 2.10 BS01 NBG A 1 H208 N254 E255 H323 Y325 E390 W432 H113 N159 E160 H228 Y230 E295 W337 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 5oyd A 2.10 BS02 BGC A 1 N132 W143 W432 N434 N37 W48 W337 N339 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 5oyd A 2.10 BS03 BGC A 2 N132 W143 N37 W48 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 5oyd A 2.10 BS04 XYS A 1 G436 D438 G341 D343 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 5oyd A 2.10 BS05 BGC A 3 A142 W143 A47 W48 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGA 5oyd B 2.10 BS03 XYS B 1 G436 D438 S441 G341 D343 S346 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAG 5oye A 1.90 BS01 BGC A 1 H208 N254 E255 Y325 E390 W432 H113 N159 E160 Y230 E295 W337 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAGA 5oye A 1.90 BS03 XYS A 1 N434 G436 D438 N339 G341 D343 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAGA 5oye A 1.90 BS04 GAL A 1 W143 W209 W48 W114 3.2.1.151 B3PD52 GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAGA 5oye B 1.90 BS02 BGC B 1 H208 N254 E255 E390 W432 H112 N158 E159 E294 W336 3.2.1.151 B3PD52 LYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNEPNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQDESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYHKYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAG 5ukg A 2.36 BS01 CA A 1 D285 D287 D289 T291 E296 D267 D269 D271 T273 E278 LIPSLTTVILVKSMLRKRSFGNPFKYNTETLYPADGGLEGACDMALKLVGGGHLNCSLETTYRSKKPATNLKMPGVYNVDHRLERIKEADDETYVELHEVAVARYGSVSELIKENMPMKLYMEGTVNNHHFKCTSEGEGKPYEGTQTMRIKVVEGGPLPFAFDILATSFSRTFIKHPPGIPDFFKQSFPEGFTWERVTTYEDGGVLTATQDTSLQDGCLIYNVKVRGMNFPANGPVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMT 5ukg A 2.36 BS02 CA A 2 D321 D323 D325 T327 F328 E332 D303 D305 D307 T309 F310 E314 LIPSLTTVILVKSMLRKRSFGNPFKYNTETLYPADGGLEGACDMALKLVGGGHLNCSLETTYRSKKPATNLKMPGVYNVDHRLERIKEADDETYVELHEVAVARYGSVSELIKENMPMKLYMEGTVNNHHFKCTSEGEGKPYEGTQTMRIKVVEGGPLPFAFDILATSFSRTFIKHPPGIPDFFKQSFPEGFTWERVTTYEDGGVLTATQDTSLQDGCLIYNVKVRGMNFPANGPVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMT 5ukg A 2.36 BS03 CA A 3 D358 D360 N362 Y364 E369 D340 D342 N344 Y346 E351 LIPSLTTVILVKSMLRKRSFGNPFKYNTETLYPADGGLEGACDMALKLVGGGHLNCSLETTYRSKKPATNLKMPGVYNVDHRLERIKEADDETYVELHEVAVARYGSVSELIKENMPMKLYMEGTVNNHHFKCTSEGEGKPYEGTQTMRIKVVEGGPLPFAFDILATSFSRTFIKHPPGIPDFFKQSFPEGFTWERVTTYEDGGVLTATQDTSLQDGCLIYNVKVRGMNFPANGPVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMT 5ukg A 2.36 BS04 CA A 4 D394 D396 D398 Q400 E405 D376 D378 D380 Q382 E387 LIPSLTTVILVKSMLRKRSFGNPFKYNTETLYPADGGLEGACDMALKLVGGGHLNCSLETTYRSKKPATNLKMPGVYNVDHRLERIKEADDETYVELHEVAVARYGSVSELIKENMPMKLYMEGTVNNHHFKCTSEGEGKPYEGTQTMRIKVVEGGPLPFAFDILATSFSRTFIKHPPGIPDFFKQSFPEGFTWERVTTYEDGGVLTATQDTSLQDGCLIYNVKVRGMNFPANGPVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMT 5un1 G 3.60 BS01 GLY G 1 F482 P514 L515 T516 R521 S678 D722 F748 F89 P121 L122 T123 R128 S276 D320 F346 A0A1L8F5J9 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIA 5un1 G 3.60 BS02 GLU G 1 E423 I426 Y454 T781 W782 E30 I33 Y61 T379 W380 A0A1L8F5J9 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIA 5un1 G 3.60 BS03 BMK G 1 V634 A635 T638 V232 A233 T236 A0A1L8F5J9 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIA 5un1 A 3.60 BS01 GLY A 1 F482 P514 L515 T516 R521 S677 S678 D722 F748 F87 P119 L120 T121 R126 S271 S272 D316 F342 A0A1L8F5J9 TRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFLTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSPATLTFENMAGVFMLVAGGIVAGIFLIFIEIA 5un1 B 3.60 BS01 GLU B 1 H479 G480 S505 L506 T507 R512 S673 H74 G75 S100 L101 T102 R107 S242 A7XY94 DEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKS 5un1 B 3.60 BS02 BMK B 1 N598 L626 T630 N175 L203 T207 A7XY94 DEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKS 5un1 H 3.60 BS01 GLU H 1 H479 S505 L506 T507 R512 G672 S673 D715 Y745 H84 S110 L111 T112 R117 G258 S259 D301 Y331 A7XY94 DEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGFTIGKAIWLLWGLVFNNSLPVQNPIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEH 5un1 E 3.60 BS01 BMK G 1 V634 T638 V228 T232 A0A1L8F5J9 TRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRLTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEELDKTWVRYQECDSRAPATLTFENMAGVFMLVAGGIVAGIFL 5un1 D 3.60 BS01 BMK B 1 L626 T630 L209 T213 A7XY94 EHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQINYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSR 5un1 D 3.60 BS02 GLU D 1 E406 H479 S505 T507 R512 S673 D715 E10 H73 S99 T101 R106 S256 D298 A7XY94 EHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQINYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSR 5un2 A 2.96 BS06 CA A 6 N2145 S2147 D2177 D2179 D2239 S2242 H2247 N215 S217 D247 D249 D309 S312 H317 Q99PF4 MNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDWEAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDVND 5un2 A 2.96 BS07 CA A 7 E2162 E2226 D2262 V2263 E232 E296 D332 V333 Q99PF4 MNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDWEAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDVND 5un2 A 2.96 BS08 CA A 8 E2162 N2224 E2226 E232 N294 E296 Q99PF4 MNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDWEAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDVND 5uwc G 2.40 BS01 FUL G 1 T82 R84 T47 R49 P26951 29374162 ITNLRMKAKAQQLTWECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRVSTWILFPENSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPPQMTAKCNKTHSFMHWKMRSHFNRKFRYELQIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARERVYEFLSAWSTPQRFEC 5uwc G 2.40 BS02 EDT G 1 W113 H115 S121 R166 W73 H75 S81 R126 P26951 29374162 ITNLRMKAKAQQLTWECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRVSTWILFPENSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPPQMTAKCNKTHSFMHWKMRSHFNRKFRYELQIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARERVYEFLSAWSTPQRFEC 5v54 A 3.90 BS01 89F A 1 W125 L126 D129 I130 C133 T134 I137 V201 T213 W327 F330 F331 T355 Y359 W88 L89 D92 I93 C96 T97 I100 V159 T171 W326 F329 F330 T349 Y353 P28222 YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDRWRTLEDNLRVIERAANAAEVREALTRMRAAAEDAQRATPPALEDRSPASPEMEDFRHGFDILVGQIDDALRLADEGRVAEAQAAAEELRTTRNAYIQKYLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 5v54 B 3.90 BS01 89F B 1 W125 L126 D129 I130 C133 T134 I137 V201 T213 A216 W327 F330 F331 S334 T355 Y359 W89 L90 D93 I94 C97 T98 I101 V165 T177 A180 W327 F330 F331 S334 T350 Y354 P28222 DYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDRWRTLEDNLRVIERAANAAEVREALTRMRAAAEDAQRATPPSPASPEMEDFRHGFDILVGQIDDALRLADEGRVAEAQAAAEELRTTRNAYIQKYLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 5v9u A 1.38 BS01 91S A 1 G10 C12 K16 P34 A59 G60 E62 R68 M72 H95 Y96 Q99 I100 V103 G10 C12 K16 P34 A59 G60 E62 R68 M72 H95 Y96 Q99 I100 V103 P01116 29373830 MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 5w92 A 2.30 BS03 KU0 A 1 Y24 K34 I38 H41 E80 F105 L106 D108 E119 I120 K134 K137 Y28 K38 I42 H45 E65 F90 L91 D93 E104 I105 K119 K122 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5w92 A 2.30 BS04 9HD A 1 M12 L16 F46 I78 G81 M16 L20 F50 I63 G66 C3W5S0 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wat A 2.14 BS01 MG A 1 S132 F134 G136 P138 S131 F133 G135 P137 2.7.1.39 P07128 AIELNVGRKVTVTVPGSSANLGPGFDTLGLALSVYDTVEVEIIPSGLEVEVFGEGQGEVPLDGSHLVVKAIRAGLKAADAEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLADFPLTQEQIVQLSSAFEGHPDNAAASVLGGAVVSWTNLSIDGKSQPQYAAVPLEVQDNIRATALVPNFHASTEAVRRVLPTEVTHIDARFNVSRVAVMIVALQQRPDLLWEGTRDRLHQPYRAEVLPITSEWVNRLRNRGYAAYLSGAGPTAMVLSTEPIPDKVLEDARESGIKVLELEVAGPVKVEVNQPHH 5wg7 A 1.45 BS01 AUD A 1 Q92 H94 V121 F131 V143 L198 T199 T200 Q89 H91 V118 F127 V139 L194 T195 T196 4.2.1.1 P00918 29266943 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wg7 A 1.45 BS02 AUD A 2 L164 D165 K168 K225 K228 L229 L160 D161 K164 K221 K224 L225 4.2.1.1 P00918 29266943 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wg7 A 1.45 BS03 AUD A 3 G102 K111 K112 K113 G99 K108 K109 K110 4.2.1.1 P00918 29266943 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wg7 A 1.45 BS04 AUD A 4 G6 Y7 G8 F231 E239 G3 Y4 G5 F227 E235 4.2.1.1 P00918 29266943 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wg7 A 1.45 BS05 AUD A 5 F131 L198 P202 F127 L194 P198 4.2.1.1 P00918 29266943 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wgp A 1.53 BS04 AUD A 3 L164 D165 K225 K228 L229 L160 D161 K221 K224 L225 4.2.1.1 P00918 29266943 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5wpx A BS01 7V9 A 1 D37 S38 L41 V44 L48 L61 S62 P63 H65 F66 V76 D37 S38 L41 V44 L48 L61 S62 P63 H65 F66 V76 A0A023GUP0 MQHASVIAQFVVEEFLPDVAPADVDVDLDLVDNGVIDSLGLLKVIAWLEDRFGIAADDVELSPEHFRSIRSIDAFVVGATTPPVEAKLQ 5x26 A 2.95 BS01 7XO A 1 L718 A743 K745 M766 T790 M793 P794 G796 D800 E804 L844 L22 A47 K49 M70 T94 M97 P98 G100 D104 E108 L148 2.7.10.1 P00533 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPEEDMDDVVDADEYLIPQ 5x27 A 2.95 BS01 7XR A 1 A743 K745 M766 T790 M793 P794 G796 E804 L844 A47 K49 M70 T94 M97 P98 G100 E108 L148 2.7.10.1 P00533 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPEEDMDDVVDADEYLIPQ 5x2a A 1.85 BS01 7XO A 1 L718 V726 A743 K745 M790 Q791 L792 M793 P794 G796 E804 L844 D855 L19 V27 A44 K46 M91 Q92 L93 M94 P95 G97 E105 L145 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVV 5x2a A 1.85 BS02 ANP A 1 G719 S720 G721 A722 V726 K745 D837 R841 N842 D855 G20 S21 G22 A23 V27 K46 D138 R142 N143 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVV 5x2a A 1.85 BS03 MG A 1 R841 N842 T854 R142 N143 T155 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVV 5x2a B 1.85 BS01 7XO B 1 L718 M793 P794 G796 L19 M94 P95 G97 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQG 5x2a B 1.85 BS02 ANP B 1 G719 G721 A722 G724 V726 A743 K745 Q791 M793 C797 D837 R841 N842 L844 D855 G20 G22 A23 G25 V27 A44 K46 Q92 M94 C98 D138 R142 N143 L145 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQG 5x2a B 1.85 BS03 MG B 1 R841 N842 T854 D855 R142 N143 T155 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQG 5x2a C 1.85 BS01 7XO C 1 V726 A743 K745 M790 Q791 M793 P794 G796 L844 D855 V27 A44 K46 M91 Q92 M94 P95 G97 L145 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADE 5x2a D 1.85 BS01 MG D 1 K745 D855 K45 D152 2.7.10.1 P00533 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEVVDAD 5x2a D 1.85 BS02 ANP D 1 S720 G721 A722 G724 V726 A743 K745 M790 Q791 M793 C797 D837 R841 N842 L844 D855 S20 G21 A22 G24 V26 A43 K45 M87 Q88 M90 C94 D134 R138 N139 L141 D152 2.7.10.1 P00533 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEVVDAD 5x2f A 2.20 BS01 7XU A 1 G719 A743 K745 M790 Q791 L792 M793 P794 G796 L844 D855 G20 A44 K46 M91 Q92 L93 M94 P95 G97 L145 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVVDAD 5x2f C 2.20 BS01 7XU C 1 L718 G719 V726 A743 K745 M790 Q791 L792 M793 P794 G796 L844 D855 L19 G20 V27 A44 K46 M91 Q92 L93 M94 P95 G97 L145 D156 2.7.10.1 P00533 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDAD 5x3j A 2.30 BS01 GLC A 1 H73 E189 Y191 W413 W414 R500 D516 E577 H73 E184 Y186 W408 W409 R495 D511 E572 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATSAAAADAAALAGGEGHLSEAQADGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5x3j A 2.30 BS02 GLC A 2 N286 A315 E319 W372 F415 F578 N281 A310 E314 W367 F410 F573 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATSAAAADAAALAGGEGHLSEAQADGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5x3j A 2.30 BS03 GLC A 3 N286 E314 W414 K449 R500 W513 D516 F549 H575 N281 E309 W409 K444 R495 W508 D511 F544 H570 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATSAAAADAAALAGGEGHLSEAQADGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5x3j B 2.30 BS02 GLC B 2 W414 F415 W405 F406 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATSAAAADAAALAGGEGHLSDGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5x3j B 2.30 BS03 GLC B 3 N286 A315 E319 W372 F415 N277 A306 E310 W363 F406 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATSAAAADAAALAGGEGHLSDGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5x3k A 2.50 BS01 GLC A 1 N286 E314 A315 E319 W372 W414 F415 N271 E299 A300 E304 W357 W399 F400 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATHLSEAQAKSLGADGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5x3k A 2.50 BS02 GLC A 2 N286 E314 W372 W414 K449 R500 W513 D516 F549 H575 N271 E299 W357 W399 K434 R485 W498 D501 F534 H560 D2PPM7 MIKHRPHGIEHPYAVSPDQRVPVLPLAGEPVLLGVVAPEADRVVCEWGTLELPLSATHLSEAQAKSLGADGAWSVQTPPLAEPVKYRFHAHRGGAAESTEWFEVSPAVWTADGVGEVRGGGERVRGVEWLVSSQGVHRGRFRLQLQDGDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVRTSRRTWYSSAGNELTVEVALGDEPVVDLAIYEGDPATVLTGFLDEVGRAEELPGWVFRLWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHAWGHDLVYADGRKGDEGNNLYPVHYARAFGDLLRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQPVFS 5xdx A 1.99 BS01 HEA A 1 A24 G27 M28 T31 S34 I37 R38 Y54 V58 H61 A62 M65 I66 M69 V70 I73 G125 W126 Y371 F377 H378 L381 S382 V386 M390 F393 M417 F425 Q428 R438 R439 V465 M468 A24 G27 M28 T31 S34 I37 R38 Y54 V58 H61 A62 M65 I66 M69 V70 I73 G125 W126 Y371 F377 H378 L381 S382 V386 M390 F393 M417 F425 Q428 R438 R439 V465 M468 1.9.3.1 P00396 MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK 5xdx J 1.99 BS02 DMU C 1 Y45 S46 Y48 C49 L50 W52 A53 Y45 S46 Y48 C49 L50 W52 A53 P07470 FENRVAEKQKLFQEDNGLPVHLKGGATDNILYRVTMTLCLGGTLYSLYCLGWASFPHK 5xdx N 1.99 BS01 HEA N 1 A24 T31 S34 I37 R38 Y54 V58 H61 A62 M65 I66 V70 I73 G125 W126 Y371 F377 H378 L381 S382 V386 M390 F393 M417 T424 F425 Q428 R438 R439 V465 M468 A24 T31 S34 I37 R38 Y54 V58 H61 A62 M65 I66 V70 I73 G125 W126 Y371 F377 H378 L381 S382 V386 M390 F393 M417 T424 F425 Q428 R438 R439 V465 M468 1.9.3.1 P00396 MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK 5xdx N 1.99 BS05 DMU P 1 L110 A114 L145 L110 A114 L145 1.9.3.1 P00396 MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK 5xdx P 1.99 BS01 DMU P 2 N38 S39 I45 N36 S37 I43 P00415 HQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSMTLLMIGLTTNMLTMYQWWRDVIRESTFQGHHTPAVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGDRKHMLQALFITITLGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS 5xdx P 1.99 BS02 DMU P 1 S29 F37 S27 F35 P00415 HQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSMTLLMIGLTTNMLTMYQWWRDVIRESTFQGHHTPAVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGDRKHMLQALFITITLGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS 5xdx W 1.99 BS02 DMU P 1 S46 Y48 C49 W52 A53 S46 Y48 C49 W52 A53 P07470 FENRVAEKQKLFQEDNGLPVHLKGGATDNILYRVTMTLCLGGTLYSLYCLGWASFPHK 5xn0 A 2.60 BS01 NUC E 1 F61 I63 D76 R78 N81 E89 Q91 L92 I94 Y115 G152 K154 P157 Q161 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 G359 H361 K374 R448 T473 Q475 Y501 F59 I61 D74 R76 N79 E87 Q89 L90 I92 Y113 G150 K152 P155 Q159 Y181 M182 D183 M228 G229 N253 Q256 K257 G260 K261 W264 V274 S278 R282 G283 K351 A353 G357 H359 K372 R446 T471 Q473 Y499 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xn0 B 2.60 BS01 NUC E 1 K22 Q269 F346 K395 K19 Q249 F326 K375 D3XFN7 29374261 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWY 5xn0 C 2.60 BS01 NUC F 1 F61 R78 N81 E89 Q91 L92 I94 Y115 G152 K154 P157 Q161 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 G359 A360 H361 K374 T473 Q475 K476 Y501 I505 F59 R76 N79 E87 Q89 L90 I92 Y113 G150 K152 P155 Q159 Y181 M182 D183 M228 G229 N253 Q256 K257 G260 K261 W264 V274 S278 R282 G283 K351 A353 G357 A358 H359 K372 T471 Q473 K474 Y499 I503 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xn1 A 2.45 BS02 ET9 A 1 K65 R72 V111 G112 D113 A114 Y115 M151 G152 M184 D185 K220 K63 R70 V109 G110 D111 A112 Y113 M149 G150 M182 D183 K218 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xn1 B 2.45 BS01 NUC E 1 K22 W266 Q269 K395 K19 W246 Q249 K375 D3XFN7 29374261 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWY 5xn1 C 2.45 BS01 NUC F 1 W24 F61 L74 D76 R78 N81 E89 Q91 L92 I94 G152 P157 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 N265 W266 V276 S280 R284 G285 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Y501 I505 W22 F59 L72 D74 R76 N79 E87 Q89 L90 I92 G150 P155 Y181 M182 D183 M228 G229 N253 Q256 K257 G260 K261 N263 W264 V274 S278 R282 G283 K351 A353 G357 A358 H359 K372 R446 T471 Q473 K474 Y499 I503 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xn1 C 2.45 BS02 ET9 C 1 R72 D110 V111 G112 D113 A114 Y115 M151 G152 M184 D185 R70 D108 V109 G110 D111 A112 Y113 M149 G150 M182 D183 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xn2 A 2.38 BS01 NUC E 1 W24 F61 I63 L74 D76 R78 N81 E89 Q91 L92 I94 G152 K154 P157 Q161 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 L289 K353 A355 G359 H361 K374 R448 T473 Q475 K476 Y501 W22 F59 I61 L72 D74 R76 N79 E87 Q89 L90 I92 G150 K152 P155 Q159 Y181 M182 D183 M228 G229 N253 Q256 K257 G260 K261 W264 V274 S278 R282 G283 L287 K351 A353 G357 H359 K372 R446 T471 Q473 K474 Y499 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xn2 C 2.38 BS01 NUC F 1 W24 F61 L74 D76 R78 N81 E89 Q91 L92 I94 D110 G152 K154 P157 Q161 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Y501 I505 W22 F59 L72 D74 R76 N79 E87 Q89 L90 I92 D108 G150 K152 P155 Q159 Y181 M182 D183 M228 G229 N253 Q256 K257 G260 K261 W264 V274 S278 R282 G283 K351 A353 G357 A358 H359 K372 R446 T471 Q473 K474 Y499 I503 D3XFN7 29374261 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5xp5 A 2.10 BS01 8BU A 1 L273 G274 Q275 G276 F278 V281 A293 T338 E339 Y340 M341 G344 S345 L393 D404 L15 G16 Q17 G18 F20 V23 A35 T80 E81 Y82 M83 G86 S87 L135 D146 2.7.10.2 P00523 AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5xp5 B 2.10 BS01 8BU B 1 F278 V281 A293 K295 E339 Y340 M341 N391 L393 D404 F20 V23 A35 K37 E81 Y82 M83 N133 L135 D146 2.7.10.2 P00523 AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5xtm A 2.10 BS01 NUC B 1 K35 G36 T37 N38 E39 K42 R46 V58 D59 I63 K84 I93 E94 V95 A96 A97 A98 K32 G33 T34 N35 E36 K39 R43 V55 D56 I60 K81 I90 E91 V92 A93 A94 A95 P62009 29372908 KPSYVKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVIIAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVAAASVAIIEPGKARDLVEEIAMKVRELMK 5xva A 1.85 BS01 8FU A 1 I327 G328 E329 G330 V335 A348 M395 E396 F397 L398 E399 G401 D444 L447 D458 I29 G30 E31 G32 V37 A50 M97 E98 F99 L100 E101 G103 D146 L149 D160 2.7.11.1 O96013 29190083 SSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 5xvf A 2.66 BS01 8FR A 1 I327 E329 A348 M395 E396 F397 L398 E399 G401 A402 D444 L447 I29 E31 A50 M97 E98 F99 L100 E101 G103 A104 D146 L149 2.7.11.1 O96013 29190083 SSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQN 5xvg A 2.10 BS01 8FX A 1 I327 G328 G330 V335 A348 K350 M395 E396 F397 L398 E399 G401 D444 L447 S457 D458 I29 G30 G32 V37 A50 K52 M97 E98 F99 L100 E101 G103 D146 L149 S159 D160 2.7.11.1 O96013 29190083 SSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 5xvh A 1.57 BS01 NAP A 1 G7 L8 G9 I10 M11 N30 R31 T32 K35 M63 V64 S65 D69 Q72 V73 S94 T95 V120 G123 G230 F231 K232 H235 K238 G20 L21 G22 I23 M24 N43 R44 T45 K48 M76 V77 S78 D82 Q85 V86 S107 T108 V133 G136 G243 F244 K245 H248 K251 A3MU08 29353380 HHHSSGLVPRGSHMRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVVIVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPVTGGQKGAIEGTLTIMVGGKEELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQVVVALNTVAMVEGLKLAKALGLDMDKVAEVLTRGAARSGAIELYLPKLLKGDLSPGFKAEHLKKDLGYVLEEARKRGVKLPGAELAYELYRKMVEDGAGSLGIHALGFY 5y7m A 3.10 BS01 NUC B 1 K35 G36 T37 N38 E39 K42 R46 D59 I63 I93 E94 V95 A96 A97 A98 K32 G33 T34 N35 E36 K39 R43 D56 I60 I90 E91 V92 A93 A94 A95 P62009 29372908 KPSYVKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVIIAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVAAASVAIIEPGKARDLVEEIAMKVRELMKLEHH 5yb6 A 2.10 BS01 FAD A 1 V51 G52 G54 I55 A56 Y74 E75 A76 K78 G81 R82 L83 G99 G100 M101 R102 F103 G300 V301 T330 C331 L335 I340 S363 Y416 W463 H468 F469 A472 F473 G507 D508 A515 W516 V517 A520 V47 G48 G50 I51 A52 Y70 E71 A72 K74 G77 R78 L79 G95 G96 M97 R98 F99 G296 V297 T326 C327 L331 I336 S359 Y412 W459 H464 F465 A468 F469 G503 D504 A511 W512 V513 A516 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb6 A 2.10 BS02 LYS A 1 R102 W235 D238 M361 Y416 W418 F473 A515 W516 R98 W231 D234 M357 Y412 W414 F469 A511 W512 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb6 A 2.10 BS03 LYS A 2 T337 Q349 W352 D356 T333 Q345 W348 D352 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb6 A 2.10 BS04 LYS C 1 E140 G141 R394 L395 E136 G137 R390 L391 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb6 B 2.10 BS03 LYS B 2 T337 E344 Q349 W352 D356 T333 E340 Q345 W348 D352 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb6 B 2.10 BS04 LYS D 1 E140 R394 L395 E136 R390 L391 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb6 C 2.10 BS02 FAD C 1 V51 G52 I55 A56 E75 A76 K78 G81 R82 L83 G99 G100 R102 F103 V301 T330 C331 L335 I340 S363 Y416 W463 H468 F469 A472 F473 G507 D508 A515 W516 V517 A520 V47 G48 I51 A52 E71 A72 K74 G77 R78 L79 G95 G96 R98 F99 V297 T326 C327 L331 I336 S359 Y412 W459 H464 F465 A468 F469 G503 D504 A511 W512 V513 A516 W6JQJ6 NRHPADGKKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb7 A 2.00 BS02 ORN A 1 R102 D238 Y416 W418 F473 A515 W516 R91 D227 Y405 W407 F462 A504 W505 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb7 A 2.00 BS04 ORN C 1 R394 L395 R383 L384 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb7 D 2.00 BS03 ORN D 2 R102 D238 Y416 W418 A515 W516 R91 D227 Y405 W407 A504 W505 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb8 A 2.30 BS02 ARG A 2 D393 R394 L395 D382 R383 L384 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb8 A 2.30 BS03 ARG A 3 E344 Q349 D356 E333 Q338 D345 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb8 A 2.30 BS04 FAD A 1 V51 G52 G54 I55 A56 E75 A76 S77 K78 G81 R82 L83 G99 G100 M101 R102 F103 G300 V301 C331 L335 I340 S363 K365 W463 F469 A472 F473 G507 D508 A515 W516 V517 V40 G41 G43 I44 A45 E64 A65 S66 K67 G70 R71 L72 G88 G89 M90 R91 F92 G289 V290 C320 L324 I329 S352 K354 W452 F458 A461 F462 G496 D497 A504 W505 V506 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb8 B 2.30 BS04 ARG C 1 T337 E344 Q349 D356 T326 E333 Q338 D345 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb8 C 2.30 BS04 FAD C 1 V51 G52 G54 I55 A56 Y74 E75 A76 G81 R82 L83 G99 G100 R102 F103 G300 V301 T330 C331 L335 I340 S363 K365 Y416 F469 A472 F473 G507 D508 A515 W516 V517 A520 V40 G41 G43 I44 A45 Y63 E64 A65 G70 R71 L72 G88 G89 R91 F92 G289 V290 T319 C320 L324 I329 S352 K354 Y405 F458 A461 F462 G496 D497 A504 W505 V506 A509 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yb8 D 2.30 BS03 ARG D 1 R102 D238 N241 M361 Y416 W418 F473 A515 W516 R91 D227 N230 M350 Y405 W407 F462 A504 W505 W6JQJ6 KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTDAWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLVVGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGAVQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD 5yj1 t 2.00 BS01 6EL t 1 H381 W383 W389 W403 F405 H51 W53 W59 W73 F75 Q8C7D2 29358579 GPTSLCCKQCQETEITTKNEIFSLSLCGPHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP 5yk0 A 2.10 BS01 ADP A 1 A136 S137 A138 S139 V143 A155 K157 Q242 E243 W244 I245 D304 A92 S93 A94 S95 V99 A111 K113 Q198 E199 W200 I201 D260 O53343 29350349 DEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLQKDAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRSVAQIRTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEPD 5yk2 A 2.81 BS01 ERY A 1 E196 E199 D286 A307 A309 I407 R410 E151 E154 D241 A262 A264 I356 R359 O53343 29350349 SKDEVTAELMEKAANQLFTVLGELKGGAMKVGQALSVMEAAIPDEFGEPYREALTKLAPPLPASKVHRVLDGQLGTKWRERFSSFNDTPVASASIGQVHKAIWSDGREVAVKIQYPGADEALRADLKTMQRMVGVLKQLSPGADVQGVVDELVERTEMELDYRLEAANQRAFAKAYHDHPRFQVPHVVASAPKVVIQEWIEGVPMAEIIRHGTTEQRDLIGTLLAELTFDAPRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKNYDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWLQKMTVSQIDRTARQMDLPAKLAIPMRVIASVGAILCQLDAHVPIKALSEELIPGFAEP 5yoq A 2.65 BS01 CLT A 1 N391 F403 L407 R410 Y411 K414 L430 V433 L453 N389 F401 L405 R408 Y409 K412 L428 V431 L451 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGK 5yoq B 2.65 BS01 CLT B 1 I388 N391 F403 R410 Y411 L430 V433 L453 S489 I382 N385 F397 R404 Y405 L424 V427 L447 S483 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFA 5yp6 A 2.20 BS01 III B 1 K336 M342 Q346 Q349 I350 L353 P500 E504 K72 M78 Q82 Q85 I86 L89 P236 E240 P51449 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 5yp6 A 2.20 BS02 4CX A 1 C285 Q286 L287 L292 W317 C320 H323 L324 M358 R364 M365 R367 A368 V376 F377 F378 F388 L391 C393 I397 I400 H479 C21 Q22 L23 L28 W53 C56 H59 L60 M94 R100 M101 R103 A104 V112 F113 F114 F124 L127 C129 I133 I136 H215 P51449 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 5yqg A 2.10 BS01 III E 1 K50 R57 R132 Y133 L177 N178 V181 N229 K51 R58 R130 Y131 L175 N176 V179 N220 P68510 FMGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELYKDSTLIMQLLRDNLTLWT 5yqg B 2.10 BS01 III E 2 R57 R132 Y133 L177 N178 V181 E185 N229 R57 R132 Y133 L177 N178 V181 E185 N229 P68510 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSD 6apw A 2.61 BS01 BTV A 1 S93 T94 Q116 G119 R120 G121 R122 R125 W127 W136 M137 N179 D180 K187 G190 F191 L192 G208 I209 G210 I224 S92 T93 Q115 G118 R119 G120 R121 R124 W126 W135 M136 N178 D179 K186 G189 F190 L191 G207 I208 G209 I223 6.3.4.15 A0A181HT70 29131575 SKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLKLEGCKIDSVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKSLVGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSVVLRPNVAFSMISKFNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANNDGIEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYNAASNIWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISADIDF 6aqq A 2.71 BS01 BVY A 1 S93 T94 Q95 Q116 G119 R120 R125 K187 G190 I209 G210 S92 T93 Q94 Q115 G118 R119 R124 K182 G185 I204 G205 6.3.4.15 A0A181HT70 29131575 SKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLKLEGCKIDSVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKSLVGNQSSFFILSDEQTKGRGRFNRHKGQGLWMSVVLRPNVAFSMISKFNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANNDGIEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISADIDF 6arj A 1.92 BS01 SAH A 1 Y149 F150 Y153 Q159 M162 R168 G192 C193 I197 L198 E214 A215 G240 K241 V242 E243 E257 M268 S271 Y16 F17 Y20 Q26 M29 R35 G59 C60 I64 L65 E81 A82 G107 K108 V109 E110 E124 M135 S138 2.1.1.319 Q86X55 29269946 RSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6arj A 1.92 BS02 BW4 A 1 F152 Y153 M162 E257 P258 M259 Y261 N265 E266 M268 H414 W415 K470 F474 T477 F19 Y20 M29 E124 P125 M126 Y128 N132 E133 M135 H281 W282 K337 F341 T344 2.1.1.319 Q86X55 29269946 RSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6arv A 2.00 BS02 BW7 A 1 Y149 F152 Y153 M162 E257 M259 Y261 E266 H414 W415 F474 Y16 F19 Y20 M29 E124 M126 Y128 E133 H281 W282 F341 2.1.1.319 Q86X55 29269946 RSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6arv C 2.00 BS02 BW7 C 1 Y149 F152 Y153 M162 E257 M259 Y261 N265 H414 W415 K470 F474 Y476 Y16 F19 Y20 M29 E124 M126 Y128 N132 H281 W282 K337 F341 Y343 2.1.1.319 Q86X55 29269946 RSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYT 6aum A 2.95 BS02 BXV A 1 F267 D335 W336 M339 I363 S374 I375 Y383 Q384 L408 M419 L428 Y466 F266 D334 W335 M338 I362 S373 I374 Y382 Q383 L407 M418 L427 Y465 3.3.2.10,3.1.3.76 P34913 29366648 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARN 6azt A 1.80 BS01 III B 1 R75 H76 D177 H178 G179 C220 S248 Y249 G250 C267 D270 R18 H19 D120 H121 G122 C163 S191 Y192 G193 C210 D213 A0A0G2RI59 29384475 GTKWAVLVAGSKGYGNYRHQADVCHAYQVLKKGGLKDENIVVFMYDDIAKSEMNPRPGIIINSPKGEDVYAGVPKDYTGKNVTVDNLSAVLLGDRSAVKGGSGKVVDSKPEDRIFLFYSDHGGPGVLGMPNEPHLVAKDLVDVLKKKHAMGTYKEMVIYLEACESGSIFEGILPEDLNIYATTASGAQENSYGTYCPGTEPSPPPEYITCLGDLYSVAWMEDSETHNLKKESLEQQFNKVKKRTSNGSHVMEYGSKDIKPEKVYLYLGFDPATV 6b8y A 1.65 BS01 D0A A 1 I211 V219 A230 V231 K232 E245 Y249 F262 L278 V279 S280 D281 Y282 H283 G286 K337 N338 L340 D351 I14 V22 A33 V34 K35 E48 Y52 F65 L81 V82 S83 D84 Y85 H86 G89 K140 N141 L143 D154 2.7.11.30 P36897 HMTIARDIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 6bdt A 2.30 BS01 CA A 1 I113 G115 D120 E199 I54 G56 D61 E140 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFQFVWKRPPEICENPRFIIDGANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTTRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTAD 6bdt A 2.30 BS02 CA A 2 E364 D371 T392 D394 E396 E252 D259 T280 D282 E284 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFQFVWKRPPEICENPRFIIDGANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTTRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTAD 6bdt B 2.30 BS02 CA B 2 I113 D114 G115 D120 E199 I56 D57 G58 D63 E142 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDSWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTAD 6bgp A 2.75 BS01 CA A 1 I113 D114 G115 N117 D120 E199 I51 D52 G53 N55 D58 E137 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQFVWKRPPEICENPRFIIDGANRTDICQGELGDAWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLT 6bgp C 2.75 BS02 CA C 2 E364 D371 Q390 T392 D394 E396 E259 D266 Q285 T287 D289 E291 3.4.22.54 P20807 KEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDAWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTA 6bja A 1.60 BS01 COA A 1 L150 M159 Y185 L225 I226 K229 L233 F237 A247 A248 S251 I253 A322 H352 L145 M154 Y180 L213 I214 K217 L221 F225 A235 A236 S239 I241 A310 H340 F1L3N8 29381332 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAGLGQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSNAPFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAYAIESYRKAEHAWKEGAFNKEVVPVSVVVLTEDEEYKRLIPEKVPALHPAFLKDGSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAVKQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGARIVVTLVHALKSDELGVAAICNGGGEASAILIKKL 6bjb A 1.50 BS01 1VU A 1 S91 L149 M158 Y184 K222 V223 N224 K227 I228 L231 A234 F235 A243 A244 S247 T248 L249 F288 A318 F319 H348 I350 C376 N377 G378 S90 L148 M157 Y183 K216 V217 N218 K221 I222 L225 A228 F229 A237 A238 S241 T242 L243 F282 A312 F313 H342 I344 C370 N371 G372 F1KYX0 29381332 RPITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTITVEEDEEYKKVNFEKIPKLKPAFTSEGSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 6bjb A 1.50 BS02 NO3 A 1 M90 S91 G148 M158 I350 N377 G378 M89 S90 G147 M157 I344 N371 G372 F1KYX0 29381332 RPITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTITVEEDEEYKKVNFEKIPKLKPAFTSEGSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 6bjb A 1.50 BS03 NO3 A 2 R70 V83 V84 R69 V82 V83 F1KYX0 29381332 RPITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTITVEEDEEYKKVNFEKIPKLKPAFTSEGSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 6bjb A 1.50 BS04 NO3 B 1 K89 N377 G381 K88 N371 G375 F1KYX0 29381332 RPITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTITVEEDEEYKKVNFEKIPKLKPAFTSEGSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 6bjb B 1.50 BS01 NO3 A 3 N377 G381 N371 G375 F1KYX0 29381332 RPITDVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTITVEEDEEYKKVNFEKIPKLKPAFTSEGSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVGHLVHTLKPGQKGCAAICNGGGGAGGMIIEKL 6bjd A 2.80 BS03 E64 A 1 Q123 G127 D128 C129 W130 K220 G222 N223 S265 G333 H334 A335 Q71 G75 D76 C77 W78 K168 G170 N171 S213 G229 H230 A231 3.4.22.54 P20807 IIGVKEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLT 6bjd B 2.80 BS03 E64 B 1 Q123 G127 C129 W130 K220 G221 G222 S265 G333 H334 Q66 G70 C72 W73 K163 G164 G165 S208 G221 H222 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDTRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLT 6bjd C 2.80 BS03 E64 C 1 Q123 G127 D128 C129 W130 G221 G222 S265 G333 H334 Q64 G68 D69 C70 W71 G162 G163 S206 G222 H223 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLT 6bkj A 3.20 BS01 III F 1 G127 C129 W130 K220 G221 G222 G71 C73 W74 K164 G165 G166 3.4.22.54 P20807 KEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLT 6bkj B 3.20 BS01 III G 1 G127 C129 W130 G221 G222 G333 H334 A335 G70 C72 W73 G164 G165 G222 H223 A224 3.4.22.54 P20807 EKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDGTRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTA 6bkj C 3.20 BS01 III H 1 C129 W130 G221 G222 S265 G333 H334 C71 W72 G163 G164 S207 G219 H220 3.4.22.54 P20807 KTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTA 6bkj D 3.20 BS01 III I 1 Q123 G127 C129 G221 G222 G333 H334 Q67 G71 C73 G165 G166 G224 H225 3.4.22.54 P20807 KEKTFEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSIDDYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNL 6bri B 3.27 BS01 HGI D 1 N44 V45 N41 V42 A3DN96 INETADDIVYRLTVIIDDRYESLKNLITLRADRLEMIINDNVSTILASI 6bsz A 2.65 BS01 GGL A 1 K71 R75 A154 A155 S156 A177 S178 T179 Y227 D309 K314 K401 K35 R39 A95 A96 S97 A118 S119 T120 Y168 D250 K255 K331 O00222 AHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVSIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLQQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASE 6bvf B 4.00 BS01 E9D B 1 F23 P25 T33 W102 I105 S106 F110 Y118 I139 L140 F23 P25 T33 W102 I105 S106 F110 Y118 I139 L140 P03147 29377794 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6bvf C 4.00 BS01 E9D B 1 V124 T128 P129 Y132 P134 V124 T128 P129 Y132 P134 P03147 29377794 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6bvf C 4.00 BS02 E9D C 1 F23 P25 L30 T33 W102 I105 S106 F110 Y118 L140 F23 P25 L30 T33 W102 I105 S106 F110 Y118 L140 P03147 29377794 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILST 6bvn C 4.00 BS01 E9D B 1 V124 R127 T128 Y132 P134 V124 R127 T128 Y132 P134 P03147 29377794 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLP 6bvn B 4.00 BS01 E9D B 1 F23 P25 D29 L30 T33 W102 I105 S106 T109 F110 Y118 N136 I139 L140 F23 P25 D29 L30 T33 W102 I105 S106 T109 F110 Y118 N136 I139 L140 P03147 29377794 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHASPHHTALRQAILAWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISALTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLP 6byp A 1.90 BS01 CA A 1 D212 D222 K224 D173 D183 K185 A0A109PTH9 SGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byp A 1.90 BS02 CA A 2 N323 N324 D326 F328 N284 N285 D287 F289 A0A109PTH9 SGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt A 2.20 BS03 83Y A 1 F80 F136 R137 R177 G262 N263 F40 F96 R97 R137 G222 N223 A0A109PTH9 GVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt A 2.20 BS04 GCB A 1 F80 H146 H167 Y243 N263 Y303 F40 H106 H127 Y203 N223 Y263 A0A109PTH9 GVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt A 2.20 BS05 83Y A 2 H87 S145 H146 Y243 H47 S105 H106 Y203 A0A109PTH9 GVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt B 2.20 BS02 CA B 2 D212 Q218 D222 K224 D174 Q180 D184 K186 A0A109PTH9 TSGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt B 2.20 BS03 83Y B 1 F80 F136 R137 H167 G262 F42 F98 R99 H129 G224 A0A109PTH9 TSGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt B 2.20 BS04 GCB B 1 F80 H146 H167 Y243 Y303 F42 H108 H129 Y205 Y265 A0A109PTH9 TSGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byt B 2.20 BS06 GCD B 1 K61 F80 T387 K23 F42 T349 A0A109PTH9 TSGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMRWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQNSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byx A 2.21 BS03 83Y A 1 R177 N263 R138 N224 A0A109PTH9 SGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMNWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byx A 2.21 BS04 GCB A 1 N263 Y303 R320 N224 Y264 R281 A0A109PTH9 SGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMNWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byx A 2.21 BS05 83Y A 2 R320 Y330 R281 Y291 A0A109PTH9 SGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMNWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byx A 2.21 BS06 GCD A 1 Y330 H384 Y291 H345 A0A109PTH9 SGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQAYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMNWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byx B 2.21 BS03 83Y B 1 G262 N263 G223 N224 A0A109PTH9 TSGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMNWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6byx B 2.21 BS05 83Y B 2 F80 R320 Y330 F41 R281 Y291 A0A109PTH9 TSGVLLESQTKITDGALHFDGKKLNHNTFENPSKSQYDYFFGRNISAHGDAVKPYKHFVFMTWYKGGKEERNVMLSRFNTKTGVVKTIQFPHRHTGFRGDPLVGESHNTIGLAVSPLNGTIHMVYDMHAYVDDDETGRFKGRFVDDFFRYSFSVAGAADVPDDEFTLEQFVKDTSELSQGADDYKHLTMTGNLQDKENFSALTYPKFYTSDDGELLHYMNWGGNNNGAYYFNKYDAKNQKWTRFTPFNHKDQKTHGNAYNWGLYGQMKYINGKLRVGFQQRSANNDDRFKYQNGVYYAYSDHPDGLGNWKNVDGEDMTWPLVNSDEIKIFEPGDYIDHTAPNSVHIVTGFDWTVTENDDVHFITHVRSTDTKRSDYKEVSIHAFKPANAVDFTITTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGSNDFEVVYQQASGVKFDHGTIHIENGKAYYYLMEKGAGNALPLHLQVIDLGV 6c0e A 1.70 BS01 EE1 A 1 I43 P108 L109 T111 S119 N121 R125 R135 R159 D313 I326 E342 T344 H345 G346 T347 A348 P349 K350 Y351 V357 N358 Y397 D398 I40 P105 L106 T108 S116 N118 R122 R132 R156 D310 I323 E339 T341 H342 G343 T344 A345 P346 K347 Y348 V354 N355 Y394 D395 1.1.1.42 Q5ZXB6 SMTYDKIKVPAQGEAITVAADHSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 6c0e A 1.70 BS02 GLY A 1 V21 D336 Q337 M338 V18 D333 Q334 M335 1.1.1.42 Q5ZXB6 SMTYDKIKVPAQGEAITVAADHSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 6c0e A 1.70 BS03 GLY A 2 A22 S26 L27 H28 A19 S23 L24 H25 1.1.1.42 Q5ZXB6 SMTYDKIKVPAQGEAITVAADHSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 6c0e A 1.70 BS04 EE1 B 1 N238 I287 Q294 R298 N235 I284 Q291 R295 1.1.1.42 Q5ZXB6 SMTYDKIKVPAQGEAITVAADHSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 6c0e B 1.70 BS01 EE1 A 1 K236 N238 I287 Q294 R298 K228 N230 I279 Q286 R290 1.1.1.42 Q5ZXB6 MTYDKIKVPAQGEAITVSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 6c0e B 1.70 BS02 EE1 B 1 I43 P108 L109 T110 T111 S119 N121 R125 R135 R159 Y166 D313 I326 G327 E342 T344 H345 G346 T347 A348 K350 Y351 V357 N358 Y397 D398 I35 P100 L101 T102 T103 S111 N113 R117 R127 R151 Y158 D305 I318 G319 E334 T336 H337 G338 T339 A340 K342 Y343 V349 N350 Y389 D390 1.1.1.42 Q5ZXB6 MTYDKIKVPAQGEAITVSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 6c4w A 2.40 BS01 HEC A 1 R13 C14 C17 H18 V28 P30 I35 S40 G41 Y46 Y48 T49 N52 W59 M64 Y67 L68 T78 K79 M80 L94 M98 R19 C20 C23 H24 V34 P36 I41 S46 G47 Y52 Y54 T55 N58 W65 M70 Y73 L74 T83 K84 M85 L99 M103 MAPFEKGSAKKGATLEKTRCLQCHTVEKGGPHKVGPNLHGIFARHSGQAEGYSYTDANIKANVEWTPNNMSEYLENPKYIPGTKMAFGGLKKEKDRNDLVTYMKKATK 6c6b A 2.00 BS01 ADP A 1 L33 A35 S36 G37 K38 S39 T40 I41 R143 T179 V182 D183 V184 L30 A32 S33 G34 K35 S36 T37 I38 R140 T173 V176 D177 V178 2.7.1.25 J9VMZ3 NITFHPGAVTQDERDTLLGQKGCTVWLTGLSASGKSTIATALEQHLLHKKLHAYRLDGDNIRFGLNKDLGFDQASRVENIRRIGEVSLLFALSSTISVTAFISPYISDRQLARELHEKHSSAIPFIEVFIDAPLSVVEQRDPKGLYKKAEIKDFTGISAPYEAPANPEIHIRTDEVDVAGAVEIITKYLADNGLIPA 6c6b D 2.00 BS01 ADP D 1 A35 S36 G37 K38 S39 T40 R143 T179 V182 D183 V184 A28 S29 G30 K31 S32 T33 R136 T167 V170 D171 V172 2.7.1.25 J9VMZ3 HPGAVTQDERDTLLGQKGCTVWLTGLSASGKSTIATALEQHLLHKKLHAYRLDGDNIRFGLNKDLGFDQASRVENIRRIGEVSLLFALSSTISVTAFISPYISDRQLARELHEKHSSAIPFIEVFIDAPLSVVEQRDPKGLYKKIKDFTGISAPYEAPANPEIHIRTDEVDVAGAVEIITKYLADNGLIPA 6c6b E 2.00 BS01 ADP E 1 A35 S36 G37 K38 S39 T40 T179 V182 V184 A28 S29 G30 K31 S32 T33 T169 V172 V174 2.7.1.25 J9VMZ3 HPGAVTQDERDTLLGQKGCTVWLTGLSASGKSTIATALEQHLLHKKLHAYRLDGDNIRFGLNKDLGFDQASRVENIRRIGEVSLLFALSSTISVTAFISPYISDRQLARELHEKHSSAIPFIEVFIDAPLSVVEQRDPKGLYKKAEIKDFTGISAPYEAPANPEIHIRTDEVDVAGAVEIITKYLADNGLIP 6c6b F 2.00 BS01 ADP F 1 L33 A35 G37 K38 S39 T40 R143 T179 V182 D183 V184 L29 A31 G33 K34 S35 T36 R139 T172 V175 D176 V177 2.7.1.25 J9VMZ3 ITFHPGAVTQDERDTLLGQKGCTVWLTGLSASGKSTIATALEQHLLHKKLHAYRLDGDNIRFGLNKDLGFDQASRVENIRRIGEVSLLFALSSTISVTAFISPYISDRQLARELHEKHSSAIPFIEVFIDAPLSVVEQRDPKGLYKKAEIKDFTGISAPYEAPANPEIHIRTDEVDVAGAVEIITKYLADNGLIPA 6c6w A 2.23 BS01 TFX A 1 A136 K137 K139 A140 F152 A136 K137 K139 A140 F152 Q8RVT0 ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTKGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMDFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA 6c8r A 1.95 BS01 SAH A 1 P21 M22 Y31 Q38 G77 S79 N83 D114 H115 G140 S141 F142 Y143 S158 Y159 A160 W163 P5 M6 Y15 Q22 G61 S63 N67 D98 H99 G124 S125 F126 Y127 S142 Y143 A144 W147 B2KPR3 VEAHPMKGGDDSHSYSQNSCYQKGVIDAAKAVIVEAVNEKLDLENNPIFDPIKPFRIADFGCSTGPNTFHAMQNIVESVETKYKSLQKTPEFHVFFNDHVNNDFNVLFRSLPPNREFFAAGVPGSFYTRVFPKNSIHFAHCSYALHWLSKVPKEIQDKNSLAYNKGRIHYTGTEKHVVKAYFGQFQRDFEGFLKARAQEIVVGGLMVIQIPGLPSGEVLFSRTGAGLLHFLLGTSLMELVNKGIINEESVDSFNLPQYHPSVEDLEMVIEMNDCFTIERVGTLPHPMKNLPFDVQRTSLQVRAIMECILTEHFGENILDPLFEIYTKNLQENFHVFDKEIRKDADLYLVLKRKGNLEH 6c8r B 1.95 BS01 SAH B 1 P21 M22 Y31 Q38 I42 G77 C78 S79 N83 D114 H115 G140 S141 F142 Y143 S158 Y159 A160 W163 P6 M7 Y16 Q23 I27 G62 C63 S64 N68 D99 H100 G125 S126 F127 Y128 S143 Y144 A145 W148 B2KPR3 AVEAHPMKGGDDSHSYSQNSCYQKGVIDAAKAVIVEAVNEKLDLENNPIFDPIKPFRIADFGCSTGPNTFHAMQNIVESVETKYKSLQKTPEFHVFFNDHVNNDFNVLFRSLPPNREFFAAGVPGSFYTRVFPKNSIHFAHCSYALHWLSKVPKEIQDKNSLAYNKGRIHYTGTEKHVVKAYFGQFQRDFEGFLKARAQEIVVGGLMVIQIPGLPSGEVLFSRTGAGLLHFLLGTSLMELVNKGIINEESVDSFNLPQYHPSVEDLEMVIEMNDCFTIERVGTLPHPMKNLPFDVQRTSLQVRAIMECILTEHFGENILDPLFEIYTKNLQENFHVFDKEIRKDADLYLVLKRKGN 6c8r B 1.95 BS02 EQV B 1 Y37 Q38 Y159 H162 W163 P227 T239 A241 L244 H245 Q273 Q316 I320 M321 Y22 Q23 Y144 H147 W148 P212 T224 A226 L229 H230 Q258 Q301 I305 M306 B2KPR3 AVEAHPMKGGDDSHSYSQNSCYQKGVIDAAKAVIVEAVNEKLDLENNPIFDPIKPFRIADFGCSTGPNTFHAMQNIVESVETKYKSLQKTPEFHVFFNDHVNNDFNVLFRSLPPNREFFAAGVPGSFYTRVFPKNSIHFAHCSYALHWLSKVPKEIQDKNSLAYNKGRIHYTGTEKHVVKAYFGQFQRDFEGFLKARAQEIVVGGLMVIQIPGLPSGEVLFSRTGAGLLHFLLGTSLMELVNKGIINEESVDSFNLPQYHPSVEDLEMVIEMNDCFTIERVGTLPHPMKNLPFDVQRTSLQVRAIMECILTEHFGENILDPLFEIYTKNLQENFHVFDKEIRKDADLYLVLKRKGN 6c8z A 2.86 BS01 ADP A 1 D310 H360 S361 K458 V460 I469 G470 D471 I473 D310 H360 S361 K458 V460 I469 G470 D471 I473 2.7.1.146 MDISEWEKRYNEAYSDISKSLKKVKGIFVAYNSNIDAIKHIDEDDIEKLLEQVDAKEVQERIMEYPRQIDSPADFVARLIISMRDGKAAEVPTYTTDIHEWLTDNLGFDEARMGGQAGIISNLLANMGIKNVIAYVPWLSKEQAEYFVDSENLLHPVVENGKLELKHPKEAYNPDNKPKVNWIIEFSKGLEVKFAGEKIVVPRDNRLIVSSRPPWIRIDMSEELYEHLPEIGKNIDGAILSGYQMIKEEYEDGKTYKDYVEKAVNVIKRLKEGNPDIRIHVEFTSIQNKLIRKAILKDIVRKHVHSLGLDTVEVANALNVLGYEELAYSVIKKDENAIVALYEGAVILLHELKLERVHVHSLGYYICVVSKDSPVSPEDHRKSLLFASTVAAARALLGNINSLDDIEAGLDVPVSEQGYNQLEKLEKYLVRRGICTLEDFENGCICTPNHDVIIIPTKVVEKPVATVGIGDTISAAAFVSVLAKMKKK 6eji A 2.30 BS01 UD2 A 1 S14 G16 R19 Y46 H118 S119 L146 N166 I189 R191 N195 K196 A221 G222 R246 V247 V250 V266 E267 G268 L269 P270 T271 E275 S14 G16 R19 Y46 H118 S119 L146 N166 I189 R191 N195 K196 A221 G222 R246 V247 V250 V266 E267 G268 L269 P270 T271 E275 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6ejj A 2.70 BS01 UDP A 1 G15 G16 R19 F45 Y46 I189 R191 K196 G222 R246 V247 V250 P270 T271 V272 E275 G15 G16 R19 F45 Y46 I189 R191 K196 G222 R246 V247 V250 P270 T271 V272 E275 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6ejj A 2.70 BS02 BUE A 1 F39 R72 K75 F39 R72 K75 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6ejj B 2.70 BS02 BUE B 1 F39 F62 K75 F39 F62 K75 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6ejk A 3.30 BS01 UDN A 1 G16 F45 Y46 H118 S119 Y123 L146 N166 I189 R191 N195 K196 R246 V247 V250 V266 E267 G268 L269 P270 T271 V272 E275 G16 F45 Y46 H118 S119 Y123 L146 N166 I189 R191 N195 K196 R246 V247 V250 V266 E267 G268 L269 P270 T271 V272 E275 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6ejk A 3.30 BS02 BUE A 1 H40 R72 K75 T97 H40 R72 K75 T97 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6ejk B 3.30 BS02 BUE B 1 F39 H40 K75 T97 F39 H40 K75 T97 O86151 MMMKISFIIATLNSGGAERVLVTLANALCKEHEVSIIKFHTGESFYKLENEVKVTSLEQFRFDTLYHKIASRFKKFFALRKALKESKADVFISFLDTTNIACILANIGLKTPLIISEHSNEAYLKPKTWRFLRRVSYPFCDALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEIPFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKNLQENYKFVIAGDGELRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEVCRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISNIKEEWLKLIVEVKNA 6eop A 2.40 BS01 III D 1 M76 R160 G162 E275 E276 Y669 V674 W754 S755 Y756 V781 W784 Y787 Y791 N835 V836 H865 S866 I867 R868 G873 Y876 E877 M29 R104 G106 E219 E220 Y613 V618 W698 S699 Y700 V725 W728 Y731 Y735 N779 V780 H809 S810 I811 R812 G817 Y820 E821 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSNRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eop A 2.40 BS02 CA A 1 R158 Q274 E275 D278 Y280 R102 Q218 E219 D222 Y224 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSNRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eop A 2.40 BS03 F15 D 1 F667 Y669 V674 K685 Y686 R688 W754 Y876 L880 F611 Y613 V618 K629 Y630 R632 W698 Y820 L824 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSNRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eop B 2.40 BS03 F15 E 1 Y669 Y686 R688 W754 Y876 L880 Y610 Y627 R629 W695 Y817 L821 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSRENTLFYSEIPKTINRAAVLMLSWKPLLDLYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eop C 2.40 BS01 III F 1 M76 R160 E275 E276 Y669 Q673 V674 K685 W754 S755 Y756 V781 W784 Y787 Y791 N835 V836 H865 S866 I867 R868 G873 Y876 E877 M29 R100 E215 E216 Y609 Q613 V614 K625 W694 S695 Y696 V721 W724 Y727 Y731 N775 V776 H805 S806 I807 R808 G813 Y816 E817 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMRENTLFYSEIPKTINRAAVLMLSWKPLLDLYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eop C 2.40 BS03 F15 F 1 F667 Y686 R688 Y876 L880 F607 Y626 R628 Y816 L820 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMRENTLFYSEIPKTINRAAVLMLSWKPLLDLYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eor A 2.90 BS01 9XH A 1 R133 E248 E249 Y644 Q648 S730 Y731 V756 W759 Y762 Y766 N810 V811 H840 R93 E205 E206 Y587 Q591 S673 Y674 V699 W702 Y705 Y709 N753 V754 H783 3.4.14.5 Q86TI2 AARFQVQKHSWDGLRSIIHGSRKAPHDFQFVQKSGPHSHRLYYLGMPYRENSLLYSEIPKLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQLCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEADYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYLHH 6eor B 2.90 BS01 9XH B 1 R133 E249 Y644 Q648 S730 Y731 V756 W759 Y762 Y766 N810 V811 H840 R98 E206 Y586 Q590 S672 Y673 V698 W701 Y704 Y708 N752 V753 H782 3.4.14.5 Q86TI2 PAARFQVQKHSWDGLRSIIHGSRKKAPHDFQFVQKTDESGPHSHRLYYLGMPRENSLLYSEIPKKLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEADYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 6eor D 2.90 BS01 9XH D 1 R133 E248 E249 Y644 Q648 V649 S730 Y731 V756 W759 Y762 Y766 N810 V811 H840 S841 R95 E206 E207 Y593 Q597 V598 S679 Y680 V705 W708 Y711 Y715 N759 V760 H789 S790 3.4.14.5 Q86TI2 PAARFQVQKHSWDGLRSIIHGSRKAPHDFQFVQKTDEGPHSHRLYYLGMPRENSLLYSEIPKLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAADYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 6eot B 3.50 BS01 III C 1 R160 E275 E276 Y669 Q673 V674 K685 W754 S755 Y756 V781 W784 Y787 Y791 N835 V836 H865 S866 I867 R868 E877 R95 E210 E211 Y604 Q608 V609 K620 W689 S690 Y691 V716 W719 Y722 Y726 N770 V771 H800 S801 I802 R803 E812 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHKAPHDFMFVKRNDPDGPHSDRIYYLAMRENTLFYSEIPKTINRAAVLMLSWKPLLDLYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eot G 3.50 BS01 III H 1 R160 E275 E276 H525 Y669 Q673 V674 K685 R688 W754 S755 Y756 V781 W784 Y787 Y791 N835 V836 H865 S866 I867 R868 G873 E877 R99 E214 E215 H464 Y608 Q612 V613 K624 R627 W693 S694 Y695 V720 W723 Y726 Y730 N774 V775 H804 S805 I806 R807 G812 E816 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHKAPHDFMFVKRNDPDGPHSDRIYYLAMRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6eot K 3.50 BS01 III L 1 R160 G162 E275 E276 Y669 Q673 V674 K685 W754 S755 Y756 V781 W784 Y787 Y791 N835 V836 H865 S866 I867 R868 G873 E877 R95 G97 E210 E211 Y604 Q608 V609 K620 W689 S690 Y691 V716 W719 Y722 Y726 N770 V771 H800 S801 I802 R803 G808 E812 3.4.14.5 Q6V1X1 LEPFYVERYSWSQLKKLLADTRKYHKAPHDFMFVKRNDPDGPHSDRIYYLAMRENTLFYSEIPKTINRAAVLMLSWKPLLDLYSREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKV 6epc S 12.30 BS01 III Y 1 R341 Q361 R314 Q334 Q5U2S7 PAPQDVEMKEEAAAGSGSAGEGDGKAAATEHSQRELDTVTLEDIKEHVRQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLES 6epc R 12.30 BS01 III Y 1 S269 V270 F272 Q273 L275 A276 E279 Q280 H291 Y292 R293 V296 R297 R300 A320 E321 G324 V325 G326 F329 E333 R336 S269 V270 F272 Q273 L275 A276 E279 Q280 H291 Y292 R293 V296 R297 R300 A320 E321 G324 V325 G326 F329 E333 R336 Q6PCT9 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDTAVREELMAAVRENNMAPYYEALCKSLDWQMDMDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 6epd S 15.40 BS01 III Y 1 D340 R341 L342 R345 D313 R314 L315 R318 Q5U2S7 PAPQDVEMKEEAAAGSGSAGEGDGKAAATEHSQRELDTVTLEDIKEHVRQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLES 6epd R 15.40 BS01 III Y 1 P15 S269 F272 Q273 K284 P290 H291 Y292 R293 V296 R297 R300 A320 E321 F323 G324 V325 F329 Q332 E333 R336 P15 S269 F272 Q273 K284 P290 H291 Y292 R293 V296 R297 R300 A320 E321 F323 G324 V325 F329 Q332 E333 R336 Q6PCT9 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDTAVREELMAAVRENNMAPYYEALCKSLDWQMDMDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 6epe S 12.80 BS01 III Y 1 I338 P339 D340 R341 Q361 R364 I311 P312 D313 R314 Q334 R337 Q5U2S7 PAPQDVEMKEEAAAGSGSAGEGDGKAAATEHSQRELDTVTLEDIKEHVRQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLES 6epe R 12.80 BS01 III Y 1 N14 D16 E47 S269 F272 A276 E279 Q280 K284 Y292 R293 V296 R297 R300 G317 A320 E321 F323 G324 V325 G326 F329 Q332 E333 R336 F337 N14 D16 E47 S269 F272 A276 E279 Q280 K284 Y292 R293 V296 R297 R300 G317 A320 E321 F323 G324 V325 G326 F329 Q332 E333 R336 F337 Q6PCT9 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDTAVREELMAAVRENNMAPYYEALCKSLDWQMDMDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 6epf S 11.80 BS01 III Y 1 D340 R341 Q361 R364 T365 D313 R314 Q334 R337 T338 Q5U2S7 PAPQDVEMKEEAAAGSGSAGEGDGKAAATEHSQRELDTVTLEDIKEHVRQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLES 6epf R 11.80 BS01 III Y 1 S269 F272 Q273 A276 E279 Q280 Y292 R293 V296 R297 R300 G317 Y318 A320 E321 G324 V325 G326 V327 F329 E333 S269 F272 Q273 A276 E279 Q280 Y292 R293 V296 R297 R300 G317 Y318 A320 E321 G324 V325 G326 V327 F329 E333 Q6PCT9 MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDTAVREELMAAVRENNMAPYYEALCKSLDWQMDMDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM 6evq A BS01 C05 A 1 F218 L221 E225 L246 Y247 T249 F28 L31 E35 L56 Y57 T59 Q61166 29138501 DEAAELMQQVKVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVIPDEGG 6ezj A 3.10 BS02 5LD A 1 H169 H170 E173 K177 H159 H160 E163 K167 4.2.1.19 O23346 RIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGG 6ezj A 3.10 BS04 5LD D 1 R99 R121 R89 R111 4.2.1.19 O23346 RIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGG 6ezj I 3.10 BS02 5LD I 1 L107 H169 H170 E173 K177 L97 H159 H160 E163 K167 4.2.1.19 O23346 RIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGG 6ezm U 3.20 BS01 MN U 1 H90 E94 H162 H83 E87 H155 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm U 3.20 BS02 MN U 2 H64 H186 E190 H57 H179 E183 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm U 3.20 BS03 5LD U 1 H64 L124 H186 H187 E190 K194 H57 L117 H179 H180 E183 K187 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm U 3.20 BS04 MN U 3 D125 H187 D118 H180 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm U 3.20 BS06 5LD E 1 R116 S214 K216 R109 S207 K209 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm G 3.20 BS02 5LD G 1 E14 H90 H91 E94 E12 H83 H84 E87 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm G 3.20 BS04 5LD G 2 H64 H186 H187 E190 K194 H57 H179 H180 E183 K187 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6ezm G 3.20 BS06 5LD I 2 R116 S214 T215 K216 R109 S207 T208 K209 4.2.1.19 P06633 EQKALVKRITNETKIQIAISLKGGPLAIEHSIFPEKAEQATQSQVINVHTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPLDEALSRAVVDLSNRPYAVVELGLQREKVGDLSCEMIPHFLESFAEASRITLHVDCLRGKNDHHRSESAFKALAVAIREATSPNGTNDVPSTKGVL 6fgx A 2.90 BS01 MG A 1 K88 D107 E174 K57 D76 E143 2.7.6.5 W8U368 FDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYAETEKYRDLLKECATEITEVEDKLQQIHSEIT 6fgx A 2.90 BS02 APC A 1 E76 R78 K80 S84 K88 R91 D107 G110 I111 R112 E174 E45 R47 K49 S53 K57 R60 D76 G79 I80 R81 E143 2.7.6.5 W8U368 FDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYAETEKYRDLLKECATEITEVEDKLQQIHSEIT 6fgx B 2.90 BS01 MG B 1 D107 E174 D75 E142 2.7.6.5 W8U368 DTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRAETEKYRDLLKECATEITEVEDKLQQIHSEIT 6fgx B 2.90 BS02 APC B 1 E76 R78 K80 S84 K88 D107 G110 I111 R112 E174 Q176 H190 E44 R46 K48 S52 K56 D75 G78 I79 R80 E142 Q144 H158 2.7.6.5 W8U368 DTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRAETEKYRDLLKECATEITEVEDKLQQIHSEIT