5mu6 A 1.88 BS01 MYA A 1 Y117 Q118 F119 W120 Y180 V181 I245 F247 L248 C249 V250 R255 S256 R258 V259 A260 P261 T268 V271 F277 A279 Y281 T282 L287 Y479 Y3 Q4 F5 W6 Y66 V67 I131 F133 L134 C135 V136 R141 S142 R144 V145 A146 P147 T154 V157 F163 A165 Y167 T168 L173 Y365 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 5mu6 A 1.88 BS03 KFK A 1 V181 F188 R189 F190 N246 T282 G284 Y296 H298 S405 Y420 N451 A452 L453 L474 L495 Q496 V67 F74 R75 F76 N132 T168 G170 Y182 H184 S291 Y306 N337 A338 L339 L360 L381 Q382 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 5mu6 B 1.88 BS03 KFK B 1 V181 D183 F188 R189 F190 N246 T282 Y296 H298 S405 Y420 N451 A452 L453 L474 L495 Q496 V67 D69 F74 R75 F76 N132 T168 Y182 H184 S291 Y301 N332 A333 L334 L355 L376 Q377 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 5mur B 3.10 BS01 PFL B 1 Y119 P120 Y197 I201 I202 M205 T255 I258 Y115 P116 Y193 I197 I198 M201 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAANILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mur E 3.10 BS01 PFL E 1 Y119 P120 Y197 I201 I202 M205 T255 I258 I259 I262 Y115 P116 Y193 I197 I198 M201 T251 I254 I255 I258 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAANILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mvn B 3.49 BS01 PFL B 1 Y119 P120 Y197 I201 I202 W205 V242 Y254 T255 I258 Y115 P116 Y193 I197 I198 W201 V238 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mvn C 3.49 BS01 PFL C 1 Y119 P120 Y197 I201 W205 V242 Y254 T255 I258 Y115 P116 Y193 I197 W201 V238 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPWLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mwc D 2.45 BS01 CA D 1 D197 D199 N201 R203 E208 D174 D176 N178 R180 E185 SLPATHELHIFGSINGVDFDMVGQGSGNPNVGYEELNLKSTKGDLQFSPWILVPHIFHQYLPYPDGMSPFQAAMVDGSGYQVHRTVQFEDGASLTVNYRYTYEGSHIKGEAQVKGTGFPADGPVMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRDPDEIFGDSDTDKNGRIDFDEFLKMVSMADWCRSKMACPNDKTLISTLKWSYTTGNGKRYRSTARTTYTFAKPMAANYLKNQPMYVFRKTELKHSKTELNFKEWQKAFTDV 5mwc D 2.45 BS02 CA D 2 D161 D163 D165 F167 E172 D147 D149 D151 F153 E158 SLPATHELHIFGSINGVDFDMVGQGSGNPNVGYEELNLKSTKGDLQFSPWILVPHIFHQYLPYPDGMSPFQAAMVDGSGYQVHRTVQFEDGASLTVNYRYTYEGSHIKGEAQVKGTGFPADGPVMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRDPDEIFGDSDTDKNGRIDFDEFLKMVSMADWCRSKMACPNDKTLISTLKWSYTTGNGKRYRSTARTTYTFAKPMAANYLKNQPMYVFRKTELKHSKTELNFKEWQKAFTDV 5mwc A 2.45 BS01 CA A 1 F206 E208 F160 E162 LPATHELHIFGSINGVDFDMVGQGSGNPNVGYEELNLKSTKGDLQFSPWILVPHIFHQYLPYPDGMSPFQAAMVDGSGYQVHRTVQFEDGASLTVNYRYTYEGSHIKGEAQVKGTGFPADGPVMANSLTAMVPSEEELSECFRTFIDREEFEDPDEIFGFDEFLKMMADWCRSKMACPNDKTLISTLKWSYTTGNGKRYRSTARTTYTFAKPMAANYLKNQPMYVFRKTELKHSKTELNFKEWQKAFTDVMGM 5mwg A 1.50 BS01 WGX A 1 I652 F653 V657 P658 E661 V662 C704 Y707 N708 F714 I23 F24 V28 P29 E32 V33 C75 Y78 N79 F85 P55201 LTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5mwg B 1.50 BS01 WGX B 1 I652 F653 V657 P658 E661 C704 Y707 N708 I713 F714 I25 F26 V30 P31 E34 C77 Y80 N81 I86 F87 P55201 MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5mwr B 2.38 BS01 MFK B 1 M72 R73 Y74 L76 K77 T80 R86 V89 G93 F97 M101 F111 H125 L129 R132 Y133 I159 A162 M59 R60 Y61 L63 K64 T67 R73 V76 G80 F84 M88 F98 H112 L116 R119 Y120 I146 A149 A0A0U3GJ51 SLNKILDASVELIADKGFLSTSINDITSKAGVAYGLFYFYFKSKHDILDEIIRQFNRNMRYYLKTYTQNLDSRIDVEKVGMKKFLEWMNENKKYYKIFIETQVHRPDIYKWHFMKLAERYTTGLSEAMRRGEIINVDPELLSYVLIGIAHMLGKRYVLWSNSGLTLKQQRDLDLIIENMLTPR 5mwt A 1.71 BS01 JB9 A 1 V31 H44 N46 R48 H52 N61 E71 R73 D123 G124 D125 V30 H43 N45 R47 H51 N60 E70 R72 D122 G123 D124 P09382 CGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD 5mwz A 1.25 BS01 KGU A 1 I652 F653 V657 P658 V662 Y665 C704 Y707 N708 F714 I27 F28 V32 P33 V37 Y40 C79 Y82 N83 F89 P55201 MEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5mxd A 2.52 BS01 III A 1 Q12 G13 L30 Y71 K107 F108 I110 I118 G230 T232 Q17 G18 L35 Y76 K112 F113 I115 I123 G235 T237 3.4.23.46 P56817 TGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 5mxd B 2.52 BS01 III B 1 Q12 L30 K107 F108 I110 I118 G230 T232 Q16 L34 K111 F112 I114 I122 G221 T223 3.4.23.46 P56817 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 5mxd C 2.52 BS01 III C 1 G11 Q12 G13 K107 F108 I110 G230 T232 G17 Q18 G19 K113 F114 I116 G225 T227 3.4.23.46 P56817 TTGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 5mxm A 2.05 BS02 ADP A 1 G213 A214 K219 G237 G238 F241 L256 G312 N336 P338 G340 V341 E343 G372 G373 D374 T375 G212 A213 K218 G236 G237 F240 L255 G311 N335 P337 G339 V340 E342 G371 G372 D373 T374 2.7.2.3 P00558 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLIKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 5mxy A 1.90 BS01 HEC A 1 H42 C43 C46 H47 L60 G61 A62 F65 W70 R78 Q82 I83 T87 M90 M91 M92 F94 H10 C11 C14 H15 L28 G29 A30 F33 W38 R46 Q50 I51 T55 M58 M59 M60 F62 Q30JB5 IDGMKLYLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFKK 5mxy A 1.90 BS02 ZN A 1 E81 E85 E49 E53 Q30JB5 IDGMKLYLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFKK 5mxy A 1.90 BS03 ZN A 2 Q41 H42 Q9 H10 Q30JB5 IDGMKLYLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFKK 5mxy A 1.90 BS04 ZN A 3 R78 Q82 G86 R46 Q50 G54 Q30JB5 IDGMKLYLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFKK 5mxz A 1.90 BS01 HEC A 1 H42 C43 T45 C46 H47 L60 G61 A62 F65 W70 R78 Q82 I83 T87 M90 M91 M92 F94 L106 H10 C11 T13 C14 H15 L28 G29 A30 F33 W38 R46 Q50 I51 T55 M58 M59 M60 F62 L74 Q30JB5 IDGMKLFLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFK 5mxz A 1.90 BS02 ZN A 1 D67 E69 D35 E37 Q30JB5 IDGMKLFLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFK 5mxz A 1.90 BS04 ZN A 3 G48 G51 N52 F65 G16 G19 N20 F33 Q30JB5 IDGMKLFLQHCKTCHGVDGNPTDLGEGLGARKFADAEWQAKTSDERIIEQINEGTPEMMMPFKEKLTPEEVKALVPVVRGFK 5myq A 1.89 BS01 HBF A 1 N12 L14 S16 Y33 T35 V37 A39 T40 W70 F72 S75 T77 W97 L99 S101 R114 N118 N11 L13 S15 Y32 T34 V36 A38 T39 W69 F71 S74 T76 W96 L98 S100 R113 N117 P02701 RKCSLTGKWTNDLGSNMTIGAVNSRGEFTGTYTTAVTATSNEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDIGDDWKATRVGINIFTRL 5myq B 1.89 BS01 HBF B 1 N12 L14 S16 Y33 T35 V37 A39 W70 F72 S73 S75 T77 W97 L99 S101 R114 N118 N11 L13 S15 Y32 T34 V36 A38 W69 F71 S72 S74 T76 W96 L98 S100 R113 N117 P02701 RKCSLTGKWTNDLGSNMTIGAVNSRGEFTGTYTTAVTATSNEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDIGDDWKATRVGINIFTRL 5myq D 1.89 BS01 HBF D 1 N12 L14 S16 Y33 T35 V37 T38 A39 T40 W70 F72 S73 S75 T77 W97 L99 R114 N118 N11 L13 S15 Y32 T34 V36 T37 A38 T39 W69 F71 S72 S74 T76 W96 L98 R113 N117 P02701 RKCSLTGKWTNDLGSNMTIGAVNSRGEFTGTYTTAVTATSNEIKESPLHGTQNTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDIGDDWKATRVGINIFTRL 5mz2 A 1.90 BS01 MG A 1 K181 D207 E208 K173 D197 E198 SVSERTRIKSDRYESGVIPYAKMGYWDAAYSVKDTDILALFRITQPGVDPVEAAAAVAGESSTATWTVVWTDLLTACERYRAKAYRVDPVPNSTDVYFAFIAYEDLFEEASLSNLTASIIGNVFGFKAISALRLEDMRIPHSYLTFQGATGIIVERERLNKYGTPLGATVKPKLGLSGKNYGRVVYEGLGGLDFLDDENINSQPFMRWRERFLNCLEGINRAAAATGEVKGSYLNITAATMEEVYKRAEYAKAIGSVVVMIDLVMGYTAIQSIAYWARENDMLLHLHRAGNSTYARQKNHGINFRVICKWMRMSGVDHIHAGTVVGKLEGDPLMIGFYDILRLTELEVNLPFGIFFEMDWASLRRCMPVASGGIHCGQMHQLIHYLGDDVVLQFGGGTIGHPDGIQAGATANRVALEAMVLARNEGADYFNNQVGPQILRDAAKTCGPLQTALDLWKDISFNYTSTDTADFAE 5mz2 A 1.90 BS02 CAP A 1 T177 K179 K181 D207 E208 H297 R298 H330 K337 L338 S382 G383 G384 G406 G407 T169 K171 K173 D197 E198 H287 R288 H320 K327 L328 S371 G372 G373 G395 G396 SVSERTRIKSDRYESGVIPYAKMGYWDAAYSVKDTDILALFRITQPGVDPVEAAAAVAGESSTATWTVVWTDLLTACERYRAKAYRVDPVPNSTDVYFAFIAYEDLFEEASLSNLTASIIGNVFGFKAISALRLEDMRIPHSYLTFQGATGIIVERERLNKYGTPLGATVKPKLGLSGKNYGRVVYEGLGGLDFLDDENINSQPFMRWRERFLNCLEGINRAAAATGEVKGSYLNITAATMEEVYKRAEYAKAIGSVVVMIDLVMGYTAIQSIAYWARENDMLLHLHRAGNSTYARQKNHGINFRVICKWMRMSGVDHIHAGTVVGKLEGDPLMIGFYDILRLTELEVNLPFGIFFEMDWASLRRCMPVASGGIHCGQMHQLIHYLGDDVVLQFGGGTIGHPDGIQAGATANRVALEAMVLARNEGADYFNNQVGPQILRDAAKTCGPLQTALDLWKDISFNYTSTDTADFAE 5mz2 A 1.90 BS03 CAP B 1 E64 T69 W70 N127 E60 T65 W66 N122 SVSERTRIKSDRYESGVIPYAKMGYWDAAYSVKDTDILALFRITQPGVDPVEAAAAVAGESSTATWTVVWTDLLTACERYRAKAYRVDPVPNSTDVYFAFIAYEDLFEEASLSNLTASIIGNVFGFKAISALRLEDMRIPHSYLTFQGATGIIVERERLNKYGTPLGATVKPKLGLSGKNYGRVVYEGLGGLDFLDDENINSQPFMRWRERFLNCLEGINRAAAATGEVKGSYLNITAATMEEVYKRAEYAKAIGSVVVMIDLVMGYTAIQSIAYWARENDMLLHLHRAGNSTYARQKNHGINFRVICKWMRMSGVDHIHAGTVVGKLEGDPLMIGFYDILRLTELEVNLPFGIFFEMDWASLRRCMPVASGGIHCGQMHQLIHYLGDDVVLQFGGGTIGHPDGIQAGATANRVALEAMVLARNEGADYFNNQVGPQILRDAAKTCGPLQTALDLWKDISFNYTSTDTADFAE 5mzl A 1.96 BS02 8ET A 1 A65 K67 L120 E121 R122 V126 L174 I185 D186 A29 K31 L84 E85 R86 V90 L138 I149 D150 2.7.11.1 P11309 PLESQYQVGPLLGSSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5mzr A 2.65 BS01 PFL A 1 Y119 P120 Y197 I201 I202 M205 V242 Y254 T255 I258 Y115 P116 Y193 I197 I198 M201 V238 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAQIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzr E 2.65 BS01 PFL E 1 Y119 P120 Y197 I201 V242 Y254 T255 I258 Y115 P116 Y193 I197 V238 Y250 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAQIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzt A 2.65 BS01 MBR A 1 P120 Y197 I201 I202 M205 T255 I258 P116 Y193 I197 I198 M201 T251 I254 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAQIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzt D 2.65 BS02 MBR D 2 I201 L241 V242 N245 I197 L237 V238 N241 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAQIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5mzt E 2.65 BS01 MBR A 4 I201 L241 N245 I197 L237 N241 Q7NDN8 VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAQIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF 5n0g A 1.57 BS01 8F5 A 1 G9 I12 Y13 S16 R39 H42 G83 A195 V198 A199 N202 G8 I11 Y12 S15 R38 H41 G82 A194 V197 A198 N201 5.4.1.2 D5AV08 PHEYEKDGAKIYVQSFATIRAEADLARFTPEEEVVVVRMIHAAGMVGLENHVRFAPGMAIAARAALEAGAPILCDARMVSEGIARARLPAKNEVICTLQDPRVPALAQEMGNTRSAAALELWRPKLEGAVVAIGNAPTALFHLLNMLEDPACPRPAAIIGCPVGFIGAAESKAALAVANPVPWVIVEGRLGGSAITVAAVNALACRKE 5n0l A 1.68 BS01 ILE A 1 N40 Y42 D60 S62 F74 F101 E104 R107 K110 S130 N40 Y42 D60 S62 F74 F101 E104 R107 K110 S130 A0A031WD25 MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVVSAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFPEEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEIL 5n0l B 1.68 BS01 ILE B 1 N40 Y42 D60 S62 F74 F101 E104 K110 V128 S130 N40 Y42 D60 S62 F74 F101 E104 K110 V128 S130 A0A031WD25 MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVVSAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFPEEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEIL 5n0l C 1.68 BS01 ILE C 1 N40 Y42 D60 S62 F74 E104 R107 K110 V128 S130 N40 Y42 D60 S62 F74 E104 R107 K110 V128 S130 A0A031WD25 MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVVSAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFPEEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEIL 5n0l D 1.68 BS01 ILE D 1 N40 Y42 D60 S62 F74 F101 E104 K110 S130 N40 Y42 D60 S62 F74 F101 E104 K110 S130 A0A031WD25 MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVVSAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFPEEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEIL 5n0l E 1.68 BS01 ILE E 1 N40 Y42 D60 S62 F101 E104 K110 V128 S130 N40 Y42 D60 S62 F101 E104 K110 V128 S130 A0A031WD25 MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVVSAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFPEEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEIL 5n0l F 1.68 BS01 ILE F 1 N40 Y42 D60 S62 E104 K110 S130 N40 Y42 D60 S62 E104 K110 S130 A0A031WD25 MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVVSAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFPEEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEIL 5n0n A 1.76 BS01 SAH A 1 I19 Y98 G99 H100 V103 F104 V105 S129 A130 F171 Q172 Y211 I212 A213 G242 V243 S244 T245 I14 Y93 G94 H95 V98 F99 V100 S124 A125 F166 Q167 Y205 I206 A207 G236 V237 S238 T239 QTKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLFQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARESGQNGFPWIVGV 5n0n A 1.76 BS02 MG A 1 G16 T26 A29 G11 T21 A24 QTKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLFQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARESGQNGFPWIVGV 5n0o A 1.44 BS02 HSE A 1 Y66 R72 Y76 Q172 Y60 R66 Y70 Q166 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAA 5n0q B 2.40 BS01 SAH B 1 Y98 H100 V103 F104 S129 A130 F171 Q172 Y211 I212 A213 G242 V243 S244 T245 Y91 H93 V96 F97 S122 A123 F164 Q165 Y204 I205 A206 G235 V236 S237 T238 KAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLEARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSVIG 5n0s A 1.95 BS01 SAM A 1 I19 A98 G99 H100 V103 F104 V105 S129 A130 F171 Q172 Y211 I212 A213 M215 G242 V243 S244 T245 I13 A92 G93 H94 V97 F98 V99 S123 A124 F165 Q166 Y205 I206 A207 M209 G236 V237 S238 T239 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFAGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARESGEEASQNGFPWVIVVGVI 5n0s A 1.95 BS02 SAM B 1 P399 W400 P393 W394 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFAGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARESGEEASQNGFPWVIVVGVI 5n0s B 1.95 BS01 SAM A 1 P399 W400 V401 P393 W394 V395 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFAGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARESGEEASQNGFPWVIVVGVIGVI 5n0t A 1.78 BS02 SAM B 1 V401 I402 V403 V384 I385 V386 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTFTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLDAARGFPWVIVVGVIGVIG 5n0u A 1.68 BS02 MG A 1 S21 A47 P217 S14 A40 P210 KAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSALNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARPWVIVVGVIGV 5n0u A 1.68 BS03 MG A 2 S163 S166 L168 Y202 I248 P249 P250 S156 S159 L161 Y195 I241 P242 P243 KAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSALNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARPWVIVVGVIGV 5n0u A 1.68 BS04 MG A 3 S31 Y32 A332 L333 D334 P335 S24 Y25 A325 L326 D327 P328 KAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSALNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARPWVIVVGVIGV 5n0u A 1.68 BS05 MG A 4 H100 G102 H109 M124 H93 G95 H102 M117 KAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSALNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAARPWVIVVGVIGV 5n0v B 1.91 BS01 SAH A 1 W400 V401 W384 V385 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTFTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSSLLDAAGFPWVIVVGVI 5n0x A 1.67 BS02 MG A 1 F135 A136 I140 F129 A130 I134 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSVVIG 5n0x A 1.67 BS03 SAM B 1 V409 I410 G411 V368 I369 G370 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPSVVIG 5n0x B 1.67 BS02 MG A 1 G102 H109 M124 G96 H103 M118 TKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYCVIDPATEAFILTKNKNCVDLYQYYDNGKSRLNTYTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRALAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCLTYEASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPHQDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDIIRRLELLPAGQVPDKKARIYPANQWEPDVPEVEPYRPSDQAAIAQLADHAPPEQYQPLATSKAMSDVMTKLALDPKALADYKADHRAFAQSVPDLTPQERAALELGDSWAIRCAMKNMPVIG 5n1e A 1.53 BS01 III B 1 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 G186 F187 T197 L198 C199 G200 T201 P202 E203 Y204 E230 P236 F239 A240 D241 P243 Y247 D328 Y330 Q84 H87 E127 F129 S130 R133 D166 K168 P169 E170 G186 F187 T197 L198 C199 G200 T201 P202 E203 Y204 E230 P236 F239 A240 D241 P243 Y247 D328 Y330 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n1e A 1.53 BS02 9NT A 1 V57 A70 V104 M120 E121 Y122 V123 E127 E170 N171 L173 T183 F327 V57 A70 V104 M120 E121 Y122 V123 E127 E170 N171 L173 T183 F327 2.7.11.11 P25321 GHMGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 5n5u A 1.60 BS01 AMP A 1 F35 H42 G44 H45 Q48 G169 G170 E172 P194 V195 L196 M205 F35 H42 G44 H45 Q48 G169 G170 E172 P194 V195 L196 M205 6.1.1.1 Q57834 MDEFELIKRNTSEIISEEELREVLKKDEKSASIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIIALADLMAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSEFQLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNSIHYEGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMRLKNAVAEELIKILEPIRKRLSAH 5n5u A 1.60 BS02 7N8 A 1 G34 E36 A65 A67 M70 Y151 Q155 S158 E162 Q173 G34 E36 A65 A67 M70 Y151 Q155 S158 E162 Q173 6.1.1.1 Q57834 MDEFELIKRNTSEIISEEELREVLKKDEKSASIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIIALADLMAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSEFQLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNSIHYEGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMRLKNAVAEELIKILEPIRKRLSAH 5nld B 0.96 BS01 LBT B 1 H48 N50 R52 V59 N61 W68 E71 H46 N48 R50 V57 N59 W66 E69 F1NZ18 29248541 ALRFEALYPEGMCPGWSVVVKGKTSSNTSMFEINFLSHPGDQIAFHFNPRFASSRIVCNSFLANHWGKEEVNKTFPFEAKEPFQVEIYSDQDYFHIFIDENKILQYKHRQKQLSSITKLQILNDIEISSVEITKRGLY 5nle D 1.85 BS01 LBT D 1 H48 N50 R52 N61 W68 E71 H46 N48 R50 N59 W66 E69 F1NZ18 29248541 ALRFEALYPEGMCPGWSVVVKGKTSSNTSMFEINFLSHPGDQIAFHFNPRFASSRIVCNSFLANHWGKEEVNKTFPFEAKEPFQVEIYSDQDYFHIFIDENKILQYKHRQKQLSSITKLQILNDIEISSVEITKRGLY 5nm7 G 1.72 BS01 GLY G 1 D54 I56 G58 P59 K60 T61 D53 I55 G57 P58 K59 T60 29109551 YKTLRLGDRGADVSYLQRQLIAAGARLDIDAIYGSATRDAVMAFQATHGLVADGIAGPKTWSTLSAGRRDPRHLTDADLQRAADRLQVDLAAVRAVNEVESKGAGFLPDGRPVILYERHIMYRQLAAAGLAAKYPALVNSKRGGYAGDAAEYARLASASQISGACALEATSWGAFQIMGFHWKALGYPDVFAFVDAMKVSEAEQLEAFVRFVLADKVMLAALRSKKWAKFAELYNGKAYAENLYDVKLERAFDRYSRAAA 5nm7 G 1.72 BS02 GLY G 2 D31 I33 G35 S36 A37 T38 D30 I32 G34 S35 A36 T37 29109551 YKTLRLGDRGADVSYLQRQLIAAGARLDIDAIYGSATRDAVMAFQATHGLVADGIAGPKTWSTLSAGRRDPRHLTDADLQRAADRLQVDLAAVRAVNEVESKGAGFLPDGRPVILYERHIMYRQLAAAGLAAKYPALVNSKRGGYAGDAAEYARLASASQISGACALEATSWGAFQIMGFHWKALGYPDVFAFVDAMKVSEAEQLEAFVRFVLADKVMLAALRSKKWAKFAELYNGKAYAENLYDVKLERAFDRYSRAAA 5nm7 G 1.72 BS03 GLY G 3 A208 L211 E212 A202 L205 E206 29109551 YKTLRLGDRGADVSYLQRQLIAAGARLDIDAIYGSATRDAVMAFQATHGLVADGIAGPKTWSTLSAGRRDPRHLTDADLQRAADRLQVDLAAVRAVNEVESKGAGFLPDGRPVILYERHIMYRQLAAAGLAAKYPALVNSKRGGYAGDAAEYARLASASQISGACALEATSWGAFQIMGFHWKALGYPDVFAFVDAMKVSEAEQLEAFVRFVLADKVMLAALRSKKWAKFAELYNGKAYAENLYDVKLERAFDRYSRAAA 5nsd A 2.05 BS01 96Q A 1 Y188 H191 F193 R196 K216 G217 D219 Y240 V242 A244 S275 I309 R311 R349 A379 Y171 H174 F176 R179 K199 G200 D202 Y223 V225 A227 S258 I292 R294 R332 A362 2.4.2.12 P43490 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLN 5nsd A 2.05 BS02 96Q B 1 Y18 Q92 Y11 Q75 2.4.2.12 P43490 EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLN 5o38 A 1.20 BS01 9JB A 1 W370 P371 F372 V376 L381 V383 Y428 N429 H433 D434 V435 M438 W28 P29 F30 V34 L39 V41 Y86 N87 H91 D92 V93 M96 P25440 MGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGVHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 5o38 A 1.20 BS02 DQW A 1 Y426 R440 Q443 D444 E447 F448 Y84 R98 Q101 D102 E105 F106 P25440 MGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGVHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 5o39 A 1.74 BS01 31O A 1 W370 P371 F372 L381 V383 C425 Y428 N429 D434 V435 M438 W27 P28 F29 L38 V40 C82 Y85 N86 D91 V92 M95 P25440 GKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGVHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 5o3b C 1.95 BS01 9HZ C 1 W370 P371 F372 V376 L381 V383 Y386 C425 Y428 N429 H433 D434 V435 M438 W25 P26 F27 V31 L36 V38 Y41 C80 Y83 N84 H88 D89 V90 M93 P25440 LSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGVHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 5o3c A 1.60 BS02 DQW A 1 Y426 R440 D444 E447 F448 Y82 R96 D100 E103 F104 P25440 KLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGVHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 5o3i A 1.20 BS01 9HN A 1 W370 P371 F372 V376 L381 V383 Y386 Y428 N429 H433 V435 M438 W27 P28 F29 V33 L38 V40 Y43 Y85 N86 H90 V92 M95 P25440 GKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGVHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 5o9w A 1.85 BS01 AKG A 1 R219 N221 Y223 L235 H238 D240 L247 L256 H295 R305 S307 A309 F311 R211 N213 Y215 L227 H230 D232 L239 L248 H287 R297 S299 A301 F303 1.14.11.31 D4N500 29408320 SNAMEKAKLMKLGNGMEIPSVQELAKLTLAEIPSRYVCALLPMGETIPVIDIENLLSPEPIIGKLELDRLHFACKEWGFFQVVNHGVDASLVDSVKSEIQGFFNLSMDEKTKYEQEDGDVEGFGQGFIESEDQTLDWADIFMMFTLPLHLRKPHLFSKLPVPLRETIESYSSEMKKLSMVLFNKMEKALQVQAAEIKGMSEVFIDGTQAMRMNYYPPCPQPNLAIGLTSHSDFGGLTILLQINEVEGLQIKREGTWISVKPLPNAFVVNVGDILEIMTNGIYHSVDHRAVVNSTNERLSIATFHDPSLESVIGPISSLITPETPALFKSGSTYGDLVEECKTRKLDGKSFLDSMRI 5obi A 1.60 BS01 SF4 A 1 S290 R291 M292 I296 C329 C332 K333 K334 C335 C390 P391 F392 F412 S290 R291 M292 I296 C329 C332 K333 K334 C335 C390 P391 F392 F412 W6EQP0 29378885 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 5obi A 1.60 BS03 OBL A 1 I22 Y31 T36 A37 F38 Y170 T242 Y246 M249 N272 G275 Q276 S277 V278 A279 A289 M292 G293 A294 C295 P302 V304 R305 L306 H357 N358 Q359 K362 L363 Q364 Y369 C372 W376 Y382 C386 V387 I22 Y31 T36 A37 F38 Y170 T242 Y246 M249 N272 G275 Q276 S277 V278 A279 A289 M292 G293 A294 C295 P302 V304 R305 L306 H357 N358 Q359 K362 L363 Q364 Y369 C372 W376 Y382 C386 V387 W6EQP0 29378885 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 5of9 A 1.81 BS01 ZN A 1 C499 C502 C525 C536 C488 C491 C510 C521 Q9Y6X9 NYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFR 5of9 A 1.81 BS02 ANP A 1 N39 A40 A43 D68 G72 M73 V81 S87 K89 G98 Q99 Y100 G101 N102 G103 L104 K105 T197 K427 N35 A36 A39 D64 G68 M69 V77 S83 K85 G94 Q95 Y96 G97 N98 G99 L100 K101 T193 K416 Q9Y6X9 NYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFR 5ofa B 2.57 BS02 ANP B 1 E35 N39 A43 D68 M73 V81 S87 K89 G98 Q99 Y100 G101 N102 G103 L104 K105 T197 K427 E31 N35 A39 D64 M69 V77 S83 K85 G94 Q95 Y96 G97 N98 G99 L100 K101 T193 K417 Q9Y6X9 NYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAEEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPRHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTF 5ofb B 2.02 BS03 MG B 1 D69 G70 S195 D69 G70 S195 Q9Y6X9 MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKLAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFR 5oic A 1.87 BS02 9VQ A 1 G96 F97 M98 M103 F149 Y158 M161 M199 I202 G94 F95 M96 M101 F147 Y156 M159 M197 I200 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oif A 2.03 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 P193 I194 M199 G12 I13 I14 S18 I19 F39 L61 D62 V63 S92 I93 G94 I120 M145 D146 F147 K163 P191 I192 M197 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oif A 2.03 BS02 9W5 A 1 G96 M98 M103 F149 M161 G94 M96 M101 F147 M159 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oif B 2.03 BS02 9W5 B 1 G96 F97 M98 M103 F149 M161 G94 F95 M96 M101 F147 M159 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oil A 2.76 BS02 9VW A 1 G96 F97 F149 Y158 P193 M199 L218 E219 G94 F95 F147 Y156 P191 M197 L216 E217 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oim A 1.91 BS01 9VZ A 1 G96 F97 M98 M103 F149 M161 M199 I202 L207 G94 F95 M96 M101 F147 M159 M197 I200 L205 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oim A 1.91 BS03 ETX A 1 S19 H24 I194 K233 D234 A235 T236 S17 H22 I192 K231 D232 A233 T234 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oim A 1.91 BS04 ETX A 2 S19 R195 T196 L197 S200 S17 R193 T194 L195 S198 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oin A 2.82 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 M161 K165 P193 I194 T196 A198 G13 I14 I15 S19 I20 F40 L62 D63 V64 S93 I94 G95 I121 M146 D147 F148 M160 K164 P192 I193 T195 A197 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oin B 2.82 BS01 9W2 B 1 G96 F97 M98 M103 Y158 M199 I202 G94 F95 M96 M101 Y156 M197 I200 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oin C 2.82 BS01 9W2 C 1 G96 F97 M98 Y158 M161 M199 G94 F95 M96 Y156 M159 M197 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oin D 2.82 BS01 9W2 D 1 G96 F97 M98 M103 Y158 M161 M199 G94 F95 M96 M101 Y156 M159 M197 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oio A 2.74 BS01 9VT A 1 G96 F97 M98 M103 F149 Y158 M161 K165 A198 M199 I202 V203 G95 F96 M97 M102 F148 Y157 M160 K164 A197 M198 I201 V202 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oio B 2.74 BS01 9VT B 1 G96 F97 M98 Q100 M103 F149 Y158 M161 M199 I202 L207 G95 F96 M97 Q99 M102 F148 Y157 M160 M198 I201 L206 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oip A 1.71 BS02 9WE A 1 G96 F97 M98 M103 F149 Y158 M161 P193 M199 L218 E219 G95 F96 M97 M102 F148 Y157 M160 P192 M198 L217 E218 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oiq A 2.65 BS01 9WB A 1 G96 M103 F149 Y158 M161 M199 G94 M101 F147 Y156 M159 M197 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oiq B 2.65 BS01 9WB B 1 G96 M103 F149 Y158 M161 P193 T196 G95 M102 F148 Y157 M160 P192 T195 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oiq C 2.65 BS01 9WB C 1 G96 M103 F149 Y158 P193 G94 M101 F147 Y156 P191 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oiq D 2.65 BS01 9WB D 1 G96 M103 F149 Y158 G94 M101 F147 Y156 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oir A 1.97 BS02 9W8 A 1 G96 F97 M98 M103 F149 Y158 M161 M199 G94 F95 M96 M101 F147 Y156 M159 M197 1.3.1.9 P9WGR1 29399991 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5ois B 2.24 BS01 9WK B 1 G96 F97 M98 Q100 M103 F149 M161 T196 A198 M199 A201 I202 A206 L207 G95 F96 M97 Q99 M102 F148 M160 T195 A197 M198 A200 I201 A205 L206 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oit B 2.58 BS01 9WH B 1 G96 F97 M98 M103 G104 F149 A157 Y158 M161 T196 A198 M199 I202 L207 I215 G95 F96 M97 M102 G103 F148 A156 Y157 M160 T195 A197 M198 I201 L206 I214 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oit D 2.58 BS01 9WH D 1 G96 F97 M98 Q100 M103 G104 F149 A157 Y158 M161 T196 A198 M199 A206 L207 I215 G95 F96 M97 Q99 M102 G103 F148 A156 Y157 M160 T195 A197 M198 A205 L206 I214 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oit F 2.58 BS01 9WH F 1 G96 F97 M98 Q100 M103 G104 F149 A157 Y158 M161 M199 I202 L207 I215 G95 F96 M97 Q99 M102 G103 F148 A156 Y157 M160 M198 I201 L206 I214 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oit H 2.58 BS01 9WH H 1 F97 M98 Q100 M103 G104 F149 A157 Y158 M161 M199 I202 I215 F96 M97 Q99 M102 G103 F148 A156 Y157 M160 M198 I201 I214 1.3.1.9 P9WGR1 29399991 AGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5oqt A 2.86 BS01 ALA A 1 I40 G42 T43 G44 F231 A232 I234 V317 I38 G40 T41 G42 F226 A227 I229 V312 Q5L1G5 LFRKKPIQLLMKESGAKGASLRKELGAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFILSGLACVFAALCYAEFASTVPVSGSAYTYSYATFGELIAWILGWDLILEYGVASSAVAVGWSGYFQGLLSGELPKALTSAYDPAKGTFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVVLLFLAVGVWYVKPENWTPFMPYGFSGVATGAATVFFAYIGFDAVSTAAEEVRNPQRDMPIGIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVAGFISLGAIAGITTVLLVMMYGQTRLFYAISRDGLLPKVFARISPTRQVPYVNTWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVSIGVLVLRKTQPDLKRAFRVPFVPVVPILAVLFCGYLVLQLPAMTWIGFVSWLLIGLVIYFIYGRKHSELN 5uqu A 1.70 BS01 OAA A 1 H269 N273 H305 H351 R360 R434 H242 N246 H278 H324 R333 R407 2.3.3.5,2.3.3.16 Q50I20 GSTAEPDLKTALKAVIPAKRELFKQVKERSDEVIGEVKVANVIGGMRGLKSMLWEGSVLDPEEGIRFHGKTIKDCQKELPKGTSGTEMLPEAMFWLLLTGQVPSTNQVRAFSRELAEQSHLPQHILDLIKSFPRSMHPMTQLSIAVAALNTESKFAKAYEKGLSKADYWEPTFDDSISLLAKIPRVAALVFRPDEVDQVGTQALDASQDWSYNFAELLGKGGKENQDFHDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLLGLAGPLHGLAAQEVLRWILAMQDKIGTKFTDDDVRNYLWDTLKSGRVVPGYGHAVLRKPDPRFQALMDFAATRPDVLANPVFQLVKKNSEIAPAVLTEHGKTKNPHPNVDAASGVLFYHYGFQQPLYYTVTFGVSRALGPLVQLIWDRALGLPIERPKSINLLGLKK 5uqu A 1.70 BS02 COA B 1 K192 P451 K165 P424 2.3.3.5,2.3.3.16 Q50I20 GSTAEPDLKTALKAVIPAKRELFKQVKERSDEVIGEVKVANVIGGMRGLKSMLWEGSVLDPEEGIRFHGKTIKDCQKELPKGTSGTEMLPEAMFWLLLTGQVPSTNQVRAFSRELAEQSHLPQHILDLIKSFPRSMHPMTQLSIAVAALNTESKFAKAYEKGLSKADYWEPTFDDSISLLAKIPRVAALVFRPDEVDQVGTQALDASQDWSYNFAELLGKGGKENQDFHDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLLGLAGPLHGLAAQEVLRWILAMQDKIGTKFTDDDVRNYLWDTLKSGRVVPGYGHAVLRKPDPRFQALMDFAATRPDVLANPVFQLVKKNSEIAPAVLTEHGKTKNPHPNVDAASGVLFYHYGFQQPLYYTVTFGVSRALGPLVQLIWDRALGLPIERPKSINLLGLKK 5uqu B 1.70 BS01 COA B 1 R74 L304 A308 L340 V345 V346 G348 Y349 G350 H351 A352 K399 T400 K401 N406 D408 R45 L275 A279 L311 V316 V317 G319 Y320 G321 H322 A323 K370 T371 K372 N377 D379 2.3.3.5,2.3.3.16 Q50I20 TAEPDLKTALKAVIPAKRELFKQVKERSDEVIGEVKVANVIGGMRGLKSMLWEGSVLDPEEGIRFHGKTIKDCQKELPKGTSGTEMLPEAMFWLLLTGQVPSTNQVRAFSRELAEQSHLPQHILDLIKSFPRSMHPMTQLSIAVAALNTESKFAKAYEKGLSKADYWEPTFDDSISLLAKIPRVAALVFRPDEVDQVGTQALDASQDWSYNFAELLGKGGKENQDFHDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLLGLAGPLHGLAAQEVLRWILAMQDKIGTKFTDDDVRNYLWDTLKSGRVVPGYGHAVLRKPDPRFQALMDFAATRPDVLANPVFQLVKKNSEIAPAVLTEHGKTKNPHPNVDAASGVLFYHYGFQQPLYYTVTFGVSRALGPLVQLIWDRALGLPIERPKSINLLGLKK 5urd A 1.90 BS01 FMN A 1 S86 Q87 T88 G89 T90 A91 A138 T139 Y140 G143 L173 G174 N175 Y178 H180 F181 N182 D208 L212 S25 Q26 T27 G28 T29 A30 A77 T78 Y79 G82 L112 G113 N114 Y117 H119 F120 N121 D147 L151 1.6.2.4 P00388 PPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEAESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPARALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5ure A 2.30 BS03 NAP A 1 R298 V474 G534 T535 C566 R567 S596 R597 K602 Y604 Q606 D632 M636 D639 W677 R233 V409 G464 T465 C496 R497 S526 R527 K532 Y534 Q536 D562 M566 D569 W607 1.6.2.4 P00388 PPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEASSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPARALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5ure B 2.30 BS03 NAP B 1 R298 V474 G534 T535 C566 R567 S596 R597 K602 Y604 Q606 D632 N635 M636 D639 W677 S678 R231 V407 G463 T464 C495 R496 S525 R526 K531 Y533 Q535 D561 N564 M565 D568 W606 S607 1.6.2.4 P00388 PVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5urg A 2.30 BS02 FAD A 1 H319 R424 R454 Y455 Y456 S457 C472 A473 V474 Y478 G488 V489 A490 T491 T535 F632 W677 H255 R360 R390 Y391 Y392 S393 C408 A409 V410 Y414 G424 V425 A426 T427 T467 F564 W609 1.6.2.4 P00388 PPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGFARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5urg A 2.30 BS03 NAP A 1 R298 P533 G534 T535 C566 R567 S596 R597 K602 Y604 Q606 F632 M636 D639 R234 P465 G466 T467 C498 R499 S528 R529 K534 Y536 Q538 F564 M568 D571 1.6.2.4 P00388 PPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGFARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5urg B 2.30 BS03 NAP B 1 R298 G534 T535 C566 R567 S596 R597 K602 Y604 Q606 F632 M636 D639 R229 G460 T461 C492 R493 S522 R523 K528 Y530 Q532 F558 M562 D565 1.6.2.4 P00388 SSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATSSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPARALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGFARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5urh A 2.50 BS03 NAP A 1 R298 P533 G534 T535 C566 R567 S596 R597 K602 Y604 Q606 A632 N635 M636 D639 S678 R233 P464 G465 T466 C497 R498 S527 R528 K533 Y535 Q537 A563 N566 M567 D570 S609 1.6.2.4 P00388 PPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEASSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGAARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5urh B 2.50 BS01 FMN B 1 S86 Q87 T88 T90 A91 A138 T139 Y140 G141 E142 G143 L173 G174 N175 Y178 H180 F181 N182 L212 S24 Q25 T26 T28 A29 A76 T77 Y78 G79 E80 G81 L111 G112 N113 Y116 H118 F119 N120 L150 1.6.2.4 P00388 PVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPARALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGAANMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5urh B 2.50 BS03 NAP B 1 R298 G534 T535 C566 S596 R597 K602 Y604 Q606 A632 M636 R231 G462 T463 C494 S524 R525 K530 Y532 Q534 A560 M563 1.6.2.4 P00388 PVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPARALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGAANMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSLDVWS 5v1d A 2.80 BS01 III E 1 W318 D358 Y388 L389 G390 M391 S401 W139 D179 Y180 L181 G182 M183 S193 A5D791 29386355 RSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSMIIPSLDGDLFQETVPFTVESLLEDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYITVIKVSVADWKVMAFNKKGGHLEWEYQFSTPIASAWLVKDGKVIPISLFDYLGMYRGQLYLQSS 5v1d C 2.80 BS01 III F 1 W165 M172 E173 D358 T360 E384 S386 V387 Y388 L389 G390 W54 M61 E62 D207 T209 E220 S222 V223 Y224 L225 G226 A5D791 29386355 SLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKMIIPSLDGDLFQWDRDRESMETVPFTVESLLEDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPSDVEEQEAVMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFSTPIASAWLVKDGKVIPISLFDDTSIVEAARGATENSVYLGMYRGQLYLQSSVRISEKF 5v1d D 2.80 BS01 III G 1 M153 W165 M172 V315 A316 W318 V387 Y388 L389 G390 M391 Y397 M46 W58 M65 V167 A168 W170 V226 Y227 L228 G229 M230 Y236 A5D791 29386355 RSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEKMIIPSLDGDLFQWDRDRESMETVPFTVESLLEDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPSDVEEQEAVMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFSTPIASAWLVKDGKVIPISLFDDTSIVEAARGATENSVYLGMYRGQLYLQSSVRISEKF 5vb9 A 1.70 BS01 III C 1 D42 L53 Y62 P63 S64 V65 I66 W67 I96 D19 L30 Y39 P40 S41 V42 I43 W44 I73 Q16552 29329326 GDKNFPRTVMVNLNIHNSDYYDRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHSPNSFRLEKILVSVGCTCVTPIVHHV 5vb9 B 1.70 BS01 III D 1 L53 Y62 P63 S64 V65 I66 W67 L27 Y36 P37 S38 V39 I40 W41 Q16552 29329326 NFPRTVMVNLNIHNSDYYDRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHSPNSFRLEKILVSVGCTCVTPI 5w6o A 2.35 BS01 9X1 A 1 Y148 A176 M177 E180 I199 F200 P201 L249 T252 Y256 E332 Y333 N337 F341 L419 W420 Y68 A71 M72 E75 I94 F95 P96 L144 T147 Y151 E227 Y228 N232 F236 L314 W315 2.7.1.32,2.7.1.82 P35790 29389115 EQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5w6o A 2.35 BS02 9X1 B 1 E175 V178 L179 E70 V73 L74 2.7.1.32,2.7.1.82 P35790 29389115 EQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5w6o B 2.35 BS02 9X1 B 1 Y148 A176 M177 E180 F200 P201 L249 T252 Y256 Y333 N337 F341 L419 W420 W423 Y69 A72 M73 E76 F96 P97 L145 T148 Y152 Y229 N233 F237 L315 W316 W319 2.7.1.32,2.7.1.82 P35790 29389115 DEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5wj1 A 2.52 BS02 FAD A 1 R246 G307 G308 G309 T331 L332 M333 M348 L349 G350 M351 H352 G371 R373 R377 V378 D395 I396 D397 E400 G413 D414 V415 Q489 M490 G508 G509 G511 M570 R161 G222 G223 G224 T246 L247 M248 M263 L264 G265 M266 H267 G286 R288 R292 V293 D310 I311 D312 E315 G328 D329 V330 Q404 M405 G423 G424 G426 M485 2.2.1.6 P17597 TFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRFVELTGIPVASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGVWRNELNVQKQKFPLSFKTFGEAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAARVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVITEGDGR 5wkc A 2.33 BS03 FAD A 1 R241 G307 A308 G309 N312 T334 L335 Q336 L352 G353 M354 H355 G374 A375 R376 R380 V381 E407 V408 N412 G425 D426 A427 Q501 M502 G520 G521 M582 R157 G211 A212 G213 N216 T238 L239 Q240 L256 G257 M258 H259 G278 A279 R280 R284 V285 E311 V312 N316 G329 D330 A331 Q405 M406 G424 G425 M486 2.2.1.6 P07342 MDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH 5wkc A 2.33 BS06 PXD D 1 G116 A117 L119 V191 A200 F201 K251 G32 A33 L35 V107 A116 F117 K167 2.2.1.6 P07342 MDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH 5wkc D 2.33 BS01 PXD A 1 G116 A117 L119 V191 F201 K251 G33 A34 L36 V108 F118 K168 2.2.1.6 P07342 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH 5wkc D 2.33 BS02 AUJ A 1 Y113 P114 G115 G116 E139 T162 P165 N169 Q202 Y30 P31 G32 G33 E56 T79 P82 N86 Q119 2.2.1.6 P07342 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH 5wkc D 2.33 BS04 PXD D 1 M354 R380 M582 V583 W586 M263 R289 M491 V492 W495 2.2.1.6 P07342 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH 5x4h A 2.80 BS01 MG A 1 D36 D83 H106 D165 D37 D84 H107 D166 Q8TZE0 HMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSDLGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4i A 2.09 BS01 MN A 1 D36 H106 H107 D165 D37 H107 H108 D166 Q8TZE0 HMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4j A 2.04 BS01 ZN A 1 D36 H106 D165 D38 H108 D167 Q8TZE0 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4k A 1.75 BS02 ZN A 2 H32 D34 H34 D36 Q8TZE0 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4k A 1.75 BS03 C5P A 1 H32 H107 K406 S408 R410 G437 G438 G439 A444 G445 H34 H109 K408 S410 R412 G439 G440 G441 A446 G447 Q8TZE0 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4k A 1.75 BS04 C5P A 2 H32 D34 H106 H107 V131 D165 M166 N169 R410 H440 I442 A443 H34 D36 H108 H109 V133 D167 M168 N171 R412 H442 I444 A445 Q8TZE0 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5x4k A 1.75 BS05 C5P A 3 T214 Y334 Q338 I375 S378 N382 R410 T216 Y336 Q340 I377 S380 N384 R412 Q8TZE0 SHMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALGREGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEKTVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNEKNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLFGRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEEEKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFATLLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNWNSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTDEDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIPRARLAEFRKLIDKILGEQVS 5xbk B 3.22 BS01 III E 1 S876 F877 G880 E884 E914 N918 F921 R956 N960 D994 E997 S170 F171 G174 E178 E208 N212 F215 R250 N254 D288 E291 Q8TEX9 29408485 PYMESVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKACQSCPSEPNTAALQAALARVVPSYMQAVNRERERQVVMAVLEALTGVLRSCGTLTLKPPGRLAELCGVLKAVLQRKTACQEYDAMLLEHAGEAIPALAAAAGGDSFAPFFAGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLPVLLSTAQEADPEVRSNAIFGMGVLAEHGGHPAQEHFPKLLGLLFPLLARERHDRVRDNICGALARLLMASPTRKPEPQVLAALLHALPLKEDLEEWVTIGRLFSFLYQSSPDQVIDVAPELLRICSLILADNKIPPDTKAALLLLLTFLAKQHTDSFQAALGSLPVDKAQELQAVLG 5yc0 A 2.00 BS01 III W 1 Q29 Q32 L33 G36 I37 Q40 N43 R46 A47 A50 Q51 H53 L54 L57 Q3 Q6 L7 G10 I11 Q14 N17 R20 A21 A24 Q25 H27 L28 L31 Q1HMR5 TVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQAR 5yc0 B 2.00 BS01 III Q 1 R31 L34 S35 V38 Q41 N42 L45 I48 E49 Q52 Q56 V59 I62 K63 R5 L8 S9 V12 Q15 N16 L19 I22 E23 Q26 Q30 V33 I36 K37 Q1HMR5 TVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL 5yc0 C 2.00 BS02 III W 1 R31 L34 S35 V38 Q41 N42 L45 I48 E49 Q52 Q56 V59 R5 L8 S9 V12 Q15 N16 L19 I22 E23 Q26 Q30 V33 Q1HMR5 TVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARI 5yc0 D 2.00 BS01 III I 1 Q29 A30 Q32 L33 G36 I37 Q39 Q40 N43 R46 A47 A50 Q51 H53 L54 L57 T58 Q3 A4 Q6 L7 G10 I11 Q13 Q14 N17 R20 A21 A24 Q25 H27 L28 L31 T32 Q1HMR5 TVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQAR 5yc0 F 2.00 BS01 III H 1 Q29 A30 L33 G36 I37 Q39 Q40 N43 L44 R46 A47 A50 Q51 H53 L54 Q3 A4 L7 G10 I11 Q13 Q14 N17 L18 R20 A21 A24 Q25 H27 L28 Q1HMR5 TVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARI 5yfj A 2.20 BS01 RUB A 1 M19 R22 G23 A24 G25 R65 C135 S137 K138 A139 Q166 A203 D204 N214 K215 K240 M17 R20 G21 A22 G23 R63 C133 S135 K136 A137 Q164 A201 D202 N212 K213 K238 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfs A 2.30 BS01 RI2 A 1 M19 R22 G23 A24 G25 R65 S135 H136 S137 K138 A139 Q166 A203 D204 N214 K215 K240 F281 M17 R20 G21 A22 G23 R63 S133 H134 S135 K136 A137 Q164 A201 D202 N212 K213 K238 F279 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yft A 2.21 BS01 RI2 A 1 M19 R22 G23 A24 G25 R65 C135 S137 K138 A139 Q166 A203 N204 N214 K215 K240 F281 M17 R20 G21 A22 G23 R63 C133 S135 K136 A137 Q164 A201 N202 N212 K213 K238 F279 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu A 2.35 BS02 AMP A 1 R124 R229 W231 D290 R122 R227 W229 D288 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu A 2.35 BS03 AMP C 1 T207 N209 A211 L250 V251 V283 P285 P286 T205 N207 A209 L248 V249 V281 P283 P284 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfu B 2.35 BS01 AMP A 1 T207 N209 A211 L250 V251 V283 P286 T205 N207 A209 L248 V249 V281 P284 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfv B 2.75 BS01 AMP A 1 T207 N209 A211 L250 V251 V283 T205 N207 A209 L248 V249 V281 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yfw C 2.35 BS01 AMP B 1 T207 N209 A211 V251 V283 P285 T205 N207 A209 V249 V281 P283 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg5 B 2.75 BS02 G B 2 E264 L267 R268 P271 I274 E275 V276 E262 L265 R266 P269 I272 E273 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg5 B 2.75 BS03 G B 1 T207 N209 A211 L250 V251 T205 N207 A209 L248 V249 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg5 B 2.75 BS04 G B 3 R229 W231 D290 R227 W229 D288 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg5 C 2.75 BS03 G C 2 E264 L267 P271 I274 E275 V276 E262 L265 P269 I272 E273 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg6 A 2.35 BS02 G A 1 P258 E264 L267 R268 P271 I274 E275 V276 P256 E262 L265 R266 P269 I272 E273 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg6 B 2.35 BS01 G A 4 T207 N209 L250 V251 V283 P285 T205 N207 L248 V249 V281 P283 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg6 C 2.35 BS02 G B 3 T207 N209 A211 L250 V251 P285 T205 N207 A209 L248 V249 P283 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg8 C 2.80 BS04 G C 1 E264 L267 W270 P271 I274 E275 V276 E262 L265 W268 P269 I272 E273 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 A 2.80 BS03 AMP C 1 N209 A211 L250 V251 V283 N207 A209 L248 V249 V281 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yg9 B 2.80 BS04 G B 1 D257 T259 E264 P271 I274 E275 V276 D255 T257 E262 P269 I272 E273 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHSHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga B 2.45 BS04 G B 1 T259 E264 R268 P271 I274 V276 T257 E262 R266 P269 I272 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yga C 2.45 BS04 G C 1 E264 L267 P271 I274 V276 E262 L265 P269 I272 V274 5.3.1.29 O57947 29382938 AMIVKEVYETAEKIKSMEIRGAGRIARAAAQALMIQAEKSKAKEPEELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGANSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEFGWALKYKEPWED 5yjw A 1.85 BS01 FAD A 1 G60 S61 G62 W63 G64 I82 S83 P84 R85 T91 P92 P95 E128 A129 A175 V176 G177 L195 K196 T239 R344 G382 D383 P391 T392 A393 A396 Y482 G26 S27 G28 W29 G30 I48 S49 P50 R51 T57 P58 P61 E94 A95 A123 V124 G125 L143 K144 T187 R292 G330 D331 P339 T340 A341 A344 Y423 1.6.5.9 P32340 SGAGPTSFKTMKVIDPSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjw A 1.85 BS04 MG A 3 R85 T91 R51 T57 1.6.5.9 P32340 SGAGPTSFKTMKVIDPSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjw A 1.85 BS06 SMA A 1 F475 Y476 R479 F416 Y417 R420 1.6.5.9 P32340 SGAGPTSFKTMKVIDPSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjw A 1.85 BS07 SMA A 2 W63 P92 A393 Q394 H397 L444 A446 L447 I459 S461 L481 M485 W29 P58 A341 Q342 H345 L385 A387 L388 I400 S402 L422 M426 1.6.5.9 P32340 SGAGPTSFKTMKVIDPSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx A 3.21 BS01 FAD A 1 G60 S61 G62 W63 G64 I82 S83 P84 R85 T91 P92 L94 E128 A129 A175 V176 G177 L195 T239 R344 V346 G382 D383 P391 T392 A393 Q394 Y482 G33 S34 G35 W36 G37 I55 S56 P57 R58 T64 P65 L67 E101 A102 A131 V132 G133 L151 T195 R300 V302 G338 D339 P347 T348 A349 Q350 Y433 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx A 3.21 BS04 MG A 3 G62 W63 R85 L89 T91 G35 W36 R58 L62 T64 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx A 3.21 BS06 MYX A 1 W63 P238 M280 T392 Q394 H397 G445 A446 L447 M485 W36 P194 M236 T348 Q350 H353 G396 A397 L398 M436 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx B 3.21 BS01 FAD B 1 G60 S61 G62 W63 G64 I82 P84 R85 T91 P92 L94 E128 A129 A175 V176 G177 L195 T239 R344 G382 D383 P391 T392 A393 Y482 G33 S34 G35 W36 G37 I55 P57 R58 T64 P65 L67 E101 A102 A131 V132 G133 L151 T195 R300 G338 D339 P347 T348 A349 Y433 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx B 3.21 BS02 MG B 1 A175 G177 I381 G382 D383 N384 A131 G133 I337 G338 D339 N340 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx B 3.21 BS05 MG B 4 G177 A178 D383 G133 A134 D339 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjx B 3.21 BS06 MYX B 1 W63 P238 M280 N341 P391 T392 A393 Q394 H397 A446 L447 Y482 M485 W36 P194 M236 N297 P347 T348 A349 Q350 H353 A397 L398 Y433 M436 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjy A 3.40 BS04 MG A 3 G62 W63 R85 F88 L89 G34 W35 R57 F60 L61 1.6.5.9 P32340 GVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjy A 3.40 BS06 8WF A 1 Q394 H397 M485 Q349 H352 M435 1.6.5.9 P32340 GVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjy B 3.40 BS02 MG B 1 A175 V176 G177 I381 D383 N384 A131 V132 G133 I337 D339 N340 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yjy B 3.40 BS06 8WF B 1 Q394 H397 L444 L447 M485 Q350 H353 L396 L399 M437 1.6.5.9 P32340 TGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL 5yx4 A 2.10 BS01 HCC A 1 R34 F45 L100 Q104 Y105 K108 R35 F46 L101 Q105 Y106 K109 G4U3G8 29394293 MMAVSELEVDGVVFPSLARPPGSAHSHFLAGAGVRGMEIGGNFIKFTAIGVYLQADAAVSALAKKWAGKAADELASDAAFFRDVVTGEFEKFTQVTMILPLTGAQYSEKVTENCVAYWKAVGAYTDAEAAAVDKFKEAFKTETFPPGASILFTHSPAGVLTVAFSKNSSVPESGGAAIENRPLCEAVLEAIIGEHGVSPAAKLSLATRVAELLKEAASVDEPAAAEPVSVSA 5z3s A 1.65 BS01 1BO A 1 F37 W78 A156 Y185 W331 F37 W78 A156 Y185 W330 Q7YS85 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVPAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGQEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGKSYTLASSKTDVGAPISGPGIPGQFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLAFPLTNAIKDVLAGV 5z4v A 1.65 BS01 MPD A 1 W10 R14 W78 T267 W331 W10 R14 W78 T266 W330 Q6TMG6 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYTFANISNNEIDTWEWNDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGPERFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKRHLTTLVKEMKAEFIREAQAGTEQLLLSAAVSAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSFTLASSKTDVGAPVSGPGIPGRFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSAVKDVLAEA 5z5c A 2.07 BS01 PLP A 1 K46 N76 G182 V183 G184 T185 G186 T188 E228 G229 I230 S272 P298 D299 K42 N72 G178 V179 G180 T181 G182 T184 E224 G225 I226 S268 P294 D295 2.5.1.47 Q8REP3 29343611 KMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISDEFIPDLVKLDKLDNVVSVDDGDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNKKYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV 5z9c A BS01 MQO A 1 W81 P82 V87 L92 L94 Y97 Y139 N140 I146 W29 P30 V35 L40 L42 Y45 Y87 N88 I94 O60885 PNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 6an1 A 2.69 BS01 BKY A 1 L228 I281 C285 R288 L330 L333 I341 S342 E343 M348 M364 L25 I67 C71 R74 L116 L119 I127 S128 E129 M134 M150 P37231 LNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 6aqs A 1.57 BS01 PO4 A 1 G23 R27 R88 G90 S91 G21 R25 R86 G88 S89 2.4.2.1 Q8T9Z7 NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAVDEMELATLMVIGTLRKVKTGGILIVDGCVPHQLENMIKIALGACAKLATKYA 6aqs A 1.57 BS02 IM5 A 1 S91 C92 Y160 D181 E182 M183 E184 D206 S89 C90 Y158 D179 E180 M181 E182 D204 2.4.2.1 Q8T9Z7 NLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAVDEMELATLMVIGTLRKVKTGGILIVDGCVPHQLENMIKIALGACAKLATKYA 6avh A 3.01 BS01 AMP A 1 I300 T302 F325 Y326 G327 S328 S329 Y348 D408 F424 Q554 K556 I278 T280 F303 Y304 G305 S306 S307 Y326 D372 F388 Q515 K517 6.-.-.- Q8GZ29 DPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSKVKFEPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSW 6avh C 3.01 BS01 AMP C 1 S97 S98 I300 T302 F325 Y326 G327 S328 S329 Y348 D408 F424 K556 S95 S96 I289 T291 F314 Y315 G316 S317 S318 Y337 D382 F398 K521 6.-.-.- Q8GZ29 PKFDPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTSSGTSGGVPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSWE 6avh D 3.01 BS01 AMP D 1 S97 S98 F219 I300 T302 F325 G327 S328 S329 Y348 D408 F424 R427 K556 S95 S96 F205 I281 T283 F306 G308 S309 S310 Y329 D375 F391 R394 K517 6.-.-.- Q8GZ29 PKFDPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTSSGTVPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSFEPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSWEL 6b2p A 3.01 BS01 CJJ A 1 L17 G18 F19 V25 A38 V72 M92 E93 Y94 V95 D96 G97 M145 M155 L14 G15 F16 V22 A35 V69 M89 E90 Y91 V92 D93 G94 M142 M152 2.7.11.1 P9WI80 29259738 PSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRVHN 6b2q A 2.88 BS01 CJJ A 1 I19 A20 V27 A40 K42 A74 M95 E96 V98 G100 N146 L148 T158 D159 I17 A18 V25 A38 K40 A72 M86 E87 V89 G91 N137 L139 T149 D150 2.7.11.1 A5TY85 29259738 PRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPS 6b2q A 2.88 BS02 0BD A 1 V106 H117 D120 I149 P151 G153 V97 H108 D111 I140 P142 G144 2.7.11.1 A5TY85 29259738 PRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPS 6b2q B 2.88 BS01 CJJ B 1 I19 A20 G22 V27 A40 K42 A74 M95 E96 V98 G100 P102 N146 L148 T158 D159 I17 A18 G20 V25 A38 K40 A72 M86 E87 V89 G91 P93 N137 L139 T149 D150 2.7.11.1 A5TY85 29259738 PRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPS 6b2q C 2.88 BS01 CJJ C 1 I19 A20 V27 A40 K42 A74 M95 E96 V98 G100 P102 G145 N146 L148 T158 D159 I17 A18 V25 A38 K40 A72 M88 E89 V91 G93 P95 G138 N139 L141 T151 D152 2.7.11.1 A5TY85 29259738 PRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPS 6b2q D 2.88 BS01 CJJ D 1 I19 A20 G22 V27 A40 K42 M95 E96 V98 G100 P102 N146 L148 T158 I17 A18 G20 V25 A38 K40 M87 E88 V90 G92 P94 N138 L140 T150 2.7.11.1 A5TY85 29259738 PRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKVMGTAQYIAPEQALGSPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRP 6b6g B 1.95 BS03 RMT B 1 C135 G136 S137 F189 H190 G191 D298 V300 Q301 K329 C125 G126 S127 F179 H180 G181 D288 V290 Q291 K319 2.6.1.19,2.6.1.22 P80147 29381352 FDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGESAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFA 6b9m A 1.68 BS01 III D 1 D144 D147 N149 M150 W153 F154 E155 Y180 D182 Y183 N186 V188 V189 R199 M216 N218 R227 G228 Y229 W230 D17 D20 N22 M23 W26 F27 E28 Y53 D55 Y56 N59 V61 V62 R72 M89 N91 R100 G101 Y102 W103 2.3.2.27 E7EZF3 29395786 SLIDPGFGFYKINEFVDARDLNMGAWFEAQIVKVTKTPAEDGGPEEIVYHVKYEDYPENGVVQLRGKDVRPRARTVYQWRQLEPGMIVMVNYNPDDPKERGYWYDAEIQRKRETRTQREVFGKILLGDAGDSLNDCRIMFVTEIYKIEEP 6b9m B 1.68 BS01 III D 1 F142 D144 W153 F154 E155 E181 D182 R199 A200 R201 M216 W230 Y272 F15 D17 W26 F27 E28 E52 D53 R70 A71 R72 M87 W101 Y143 2.3.2.27 E7EZF3 29395786 SLIDPGFGFYKINEFVDARDLNMGAWFEAQIVKVTKTPAGGPEEIVYHVKYEDYPENGVVQLRGKDVRPRARTVYQWRQLEPGMIVMVNYNPDDPKERGYWYDAEIQRKRETRTQREVFGKILLGDAGDSLNDCRIMFVTEIYKIEEP 6bdv A 1.94 BS01 III C 1 R64 H121 Q161 A162 C163 R31 H88 Q128 A129 C130 3.4.22.56 P42574 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRALTGKPKLFIIQACRGTELDCGIET 6bdv A 1.94 BS02 AZI A 1 T92 E94 E95 T59 E61 E62 3.4.22.56 P42574 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRALTGKPKLFIIQACRGTELDCGIET 6bdv B 1.94 BS02 AZI B 1 Y274 Y276 Y90 Y92 3.4.22.56 P42574 HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 6bgo C 4.20 BS01 III i 1 R26 K52 G66 K67 F71 E119 R19 K45 G59 K60 F64 E112 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bgo C 4.20 BS02 III j 1 S146 I147 S139 I140 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bgo D 4.20 BS02 III j 1 R26 L50 K52 G66 F71 R19 L43 K45 G59 F64 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bgo E 4.20 BS01 III d 1 R26 L50 K52 G66 R19 L43 K45 G59 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bgo F 4.20 BS02 III f 1 D144 S146 D137 S139 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bgo G 4.20 BS01 III f 1 R26 A27 L50 K52 G66 R19 A20 L43 K45 G59 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bgo I 4.20 BS01 III h 1 R26 A27 K28 L50 K52 G66 E119 R19 A20 K21 L43 K45 G59 E112 3.4.25.1 A5U4D5 SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRALGVASLEVAVLDANRPRRAFRRITGSALQALL 6bhq A 2.05 BS01 GAL A 1 P244 K246 M258 T260 P9 K11 M23 T25 Q58E56 29408873 GGPSVFIFPPKIKDVLMISLSPMVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNRALPSPIEKTISKPRGPVRAPQVYVLPPPAEEMTKKEFSLTCMITGFLPAEIAVDWTSNGRTEQNYKNTATVLDSDGSYFMYSKLRVQKSTWERGSLFACSVVHEGLHNHLTTKTISR 6bhq B 2.05 BS01 GAL B 1 P244 P245 K246 M258 T260 P7 P8 K9 M21 T23 Q58E56 29408873 PSVFIFPPKIKDVLMISLSPMVTCVVVDEDDPDVQISWFVNNVEVHTAQTQTHREDYLRVVSALPIQHQDWMSGKEFKCKVNNPSPIEKTISKPRGPVRAPQVYVLPPPAEEMTKKEFSLTCMITGFLPAEIAVDWTSNGRTEQNYKNTATVLDSDGSYFMYSKLRVQKSTWERGSLFACSVVHEGLHNHLTTKTISRS 6bhy A 2.04 BS01 NAG A 1 D265 N297 T299 D29 N61 T63 Q58E56 29408873 GPSVFIFPPKIKDVLMISLSPMVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNRALPSPIEKTISKPRGPVRAPQVYVLPPPAEEMTKKEFSLTCMITGFLPAEIAVDWTSNGRTEQNYKNTATVLDSDGSYFMYSKLRVQKSTWERGSLFACSVVHEGLHNHLTTKTISRSL 6bi2 L 1.80 BS01 BTN L 1 D151 K188 H189 K190 D151 K188 H189 K190 29388367 DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKAAYEKHKVYACEVTHQGLSSPVTKSFNRGE 6bka A 1.65 BS01 FMN A 1 A21 P22 M23 A24 N77 F79 H147 Q190 A194 G195 G196 G239 G240 Q259 G261 T262 L348 A21 P22 M23 A24 N77 F79 H147 Q190 A194 G195 G196 G239 G240 Q259 G261 T262 L348 1.13.12.16 Q12723 29383742 MRSQIQSFLKTFEVRYPIIQAPMAGASTLELAATVTRLGGIGSIPMGSLSEKCDAIETQLENFDELVGDSGRIVNLNFFAHKEPRSGRADVNEEWLKKYDKIYGKAGIEFDKKELKLLYPSFRSIVDPQHPTVRLLKNLKPKIVSFHFGLPHEAVIESLQASDIKIFVTVTNLQEFQQAYESKLDGVVLQGWEAGGHRGNFKANDVEDGQLKTLDLVSTIVDYIDSASISNPPFIIAAGGIHDDESIKELLQFNIAAVQLGTVWLPSSQATISPEHLKMFQSPKSDTMMTAAISGRNLRTISTPFLRDLHQSSPLASIPDYPLPYDSFKSLANDAKQSGKGPQYSAFLAGSNYHKSWKDTRSTEEIFSILVQDL 6bka A 1.65 BS02 33O A 1 E13 T34 R37 L38 V67 D69 E364 E13 T34 R37 L38 V67 D69 E364 1.13.12.16 Q12723 29383742 MRSQIQSFLKTFEVRYPIIQAPMAGASTLELAATVTRLGGIGSIPMGSLSEKCDAIETQLENFDELVGDSGRIVNLNFFAHKEPRSGRADVNEEWLKKYDKIYGKAGIEFDKKELKLLYPSFRSIVDPQHPTVRLLKNLKPKIVSFHFGLPHEAVIESLQASDIKIFVTVTNLQEFQQAYESKLDGVVLQGWEAGGHRGNFKANDVEDGQLKTLDLVSTIVDYIDSASISNPPFIIAAGGIHDDESIKELLQFNIAAVQLGTVWLPSSQATISPEHLKMFQSPKSDTMMTAAISGRNLRTISTPFLRDLHQSSPLASIPDYPLPYDSFKSLANDAKQSGKGPQYSAFLAGSNYHKSWKDTRSTEEIFSILVQDL 6bni A 1.85 BS01 LYS A 1 G249 A250 A271 E273 R295 E311 Y313 N467 A468 Y469 E471 G516 W517 G518 G206 A207 A228 E230 R252 E268 Y270 N424 A425 Y426 E428 G473 W474 G475 6.1.1.6 Q5CR27 GSHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6bni A 1.85 BS02 ADN A 1 N293 E297 T302 H303 N304 F307 A309 E464 L465 G520 R523 I534 N250 E254 T259 H260 N261 F264 A266 E421 L422 G477 R480 I491 6.1.1.6 Q5CR27 GSHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 6bni B 1.85 BS01 LYS B 1 G249 A250 E273 R295 E311 Y313 N467 A468 Y469 E471 G516 W517 G518 G202 A203 E226 R248 E264 Y266 N420 A421 Y422 E424 G469 W470 G471 6.1.1.6 Q5CR27 GSHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAIDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRNV 6bqg A 3.00 BS01 ERM A 1 D134 V135 S138 T139 V208 L209 G218 A222 F327 N331 S334 V335 E347 L350 N351 Y358 D92 V93 S96 T97 V163 L164 G173 A177 F319 N323 S326 V327 E339 L342 N343 Y350 P28335 GGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQAADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVNSGINPLVYTLFNKIYRRAFSNYLRCN 6bqh A 2.70 BS01 E2J A 1 W130 D134 V135 S138 T139 I142 G218 S219 A222 F223 F320 W324 F327 F328 L350 N351 V354 Y358 W85 D89 V90 S93 T94 I97 G173 S174 A177 F178 F284 W288 F291 F292 L314 N315 V318 Y322 P28335 FKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQAADLEDNWETLNDNLKVIEKAVKDALTKMRAAALDAQKATMKDFRHGFDILQLKTTRNAYIQKYLQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVNSGINPLVYTLFNKIYRRAFSNYLRCNY 6brg A 3.50 BS01 MG A 1 R196 H199 H238 D239 D343 R125 H128 H167 D168 D264 F8WJE0 29379009 TDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPVELKAEDFIVDVINVDRVHFYEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQ 6brh A 3.40 BS02 DGT A 1 R75 K148 V149 F150 D169 Q174 R177 F197 R4 K77 V78 F79 D98 Q103 R106 F126 F8WJE0 29379009 TDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPVELKAEDFIVDVINVDRVHFYEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQ 6brh A 3.40 BS03 DGT B 1 Y187 V188 K420 I421 R494 Y116 V117 K336 I337 R410 F8WJE0 29379009 TDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPVELKAEDFIVDVINVDRVHFYEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQ 6brk A 3.50 BS01 DGT A 1 L182 R196 R238 N239 H242 H247 H265 E266 D343 Y347 D351 Y417 L111 R125 R167 N168 H171 H176 H194 E195 D264 Y268 D272 Y333 F8WJE0 29379009 TDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCRNLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPVELKAEDFIVDVINVDRVHFYEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQ 6brk A 3.50 BS02 DGT A 2 V188 F189 R415 H419 K420 V117 F118 R331 H335 K336 F8WJE0 29379009 TDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCRNLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPVELKAEDFIVDVINVDRVHFYEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQ 6brk A 3.50 BS03 DGT A 3 Y187 V188 I421 R494 Y116 V117 I337 R410 F8WJE0 29379009 TDLRTWEPEDVCSFLENRGFREKKVLDIFRDNKIAGSFLPFLDEDRLEDLGVSSLEERKKMIECIQQLSQSRIDLMKVFNDPIHGHIEFHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRALAEKQPELQISERDILCVQIAGLCRNLGHGPFSHMFDGRFIPRARPEKKWKHEQGSIEMFEHLVNSNELKLVMKNYGLVPEEDITFIKEQIMGPLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARICEVEYKVYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAFLKADPYVEITGTAGKKFRISTAIDDMEAFTKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLGETQPKREKIRKEEYERLPQEVAKAKPVELKAEDFIVDVINVDRVHFYEQLIRVYCKKKDGKSLDAAGKHFVQWCALRDFTKPQ 6byw B 2.05 BS01 MG B 1 D360 A362 I365 A699 N700 D330 A332 I335 A666 N667 A0A161XU12 29381339 CQYKIYPPLGIARVGNGPAIKPLSLSTPEVPWAHLYDTNVQYLVTQQELEQLLEEAFGGNVINEISQIKTKLKFKQEEIETITGLLGLSHLVPQQQLSRSLDNLEDIVQQIKGALLKVLSDHYLHAVKKQAQNFYIYKCDEQGNPVEKLKLTDGDKVTWRVEVANKKSFWYDYNNALDLSLHTQGSGNLSKNVSKHRLAPAMTAKRRNPNVITNSLRKQLVISSQGSVSSDNNTQVPLRGKFPANLQERHNVLQGSIECDNEGVLRFYAGNGISQALSPSSLNTDFADNSNWFDDICDGRVTAVVELKNGDTFEIQDEQSSAWVATTPPDYAPQIEPIVTMYDMVSGAALKEQDLDNLTTQFSDVFPILYRLYRMQWVNQADFTDNAVNTQIRELNSELGFAQLLDNSASAKSLREGIFNQFRNPLFDQDIDVDDPSNEWVSNSRIIPSKDETNIAAKPATSSLKLPFYPNDGIDYPGSPVQWFAIPPFMYQHLQNWAAGDFSVTQVEKESANTIEELGLFYSEQFKNSPNSALLCARGALDALYGGGFHPGVELTWPMRHNLIYSQNDYVSSVTPEINLLGLREFRLKQDLQGLNSPNMYQDFGHVIAVDNVTASIDPNSDAAWLWRSTPGDLTKWMGIPWQSDAASCQAVYTPEDFPIPSWWAANLPVHVLPLARYNKFKDSQSADLPEINGMTHSIAQGMSEETFEHLRLEQFSQRLDWLHTADLGFVGYHAEGGYTNGLIQMVSQWKNMAMVMARPVENPGSSGIPNVVYVAYSQAD 6c1a A 2.05 BS01 NUC C 1 R166 K167 S168 L170 D176 K186 R20 K21 S22 L24 D30 K40 Q9UBB5 GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1a A 2.05 BS02 NUC D 1 R188 S189 K190 P191 R195 R209 R42 S43 K44 P45 R49 R63 Q9UBB5 GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1a B 2.05 BS01 NUC C 1 R166 S168 G169 L170 S171 D176 R19 S21 G22 L23 S24 D29 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1a B 2.05 BS02 NUC D 1 R166 R188 S189 K190 P191 R209 R19 R41 S42 K43 P44 R62 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1a E 2.05 BS01 NUC G 1 R166 K167 S168 G169 L170 D176 K186 R188 R19 K20 S21 G22 L23 D29 K39 R41 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1a E 2.05 BS02 NUC H 1 R188 S189 K190 P191 R195 R41 S42 K43 P44 R48 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1t D 1.84 BS02 NUC C 1 R166 S168 G169 L170 S171 R18 S20 G21 L22 S23 Q9UBB5 RMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1u A 2.30 BS01 NUC C 1 R166 K167 S168 G169 L170 S171 D176 Y178 K186 R188 R20 K21 S22 G23 L24 S25 D30 Y32 K40 R42 Q9UBB5 GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1u A 2.30 BS02 NUC D 1 R188 S189 P191 R195 R209 R42 S43 P45 R49 R63 Q9UBB5 GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1u B 2.30 BS02 NUC D 1 R166 K174 R188 S189 K190 P191 R209 R19 K27 R41 S42 K43 P44 R62 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1u F 2.30 BS02 NUC H 1 R166 K174 R188 S189 R209 R20 K28 R42 S43 R63 Q9UBB5 GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c1v A 2.30 BS01 NUC C 1 R166 K167 S168 G169 L170 D176 Y178 K186 R188 R19 K20 S21 G22 L23 D29 Y31 K39 R41 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1v A 2.30 BS02 NUC D 1 R188 S189 P191 R41 S42 P44 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1v E 2.30 BS02 NUC H 1 S189 K190 P191 S42 K43 P44 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1v F 2.30 BS02 NUC H 1 K174 R188 S189 K190 P191 R209 K27 R41 S42 K43 P44 R62 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c1y A 2.30 BS01 NUC D 1 R133 S134 T158 V159 R42 S43 T67 V68 P51608 GPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGR 6c1y A 2.30 BS02 NUC C 1 K109 R111 K112 S113 G114 R115 S116 D121 Y123 R133 K18 R20 K21 S22 G23 R24 S25 D30 Y32 R42 P51608 GPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGR 6c1y B 2.30 BS01 NUC F 1 R133 S134 V136 F157 T158 V159 R42 S43 V45 F66 T67 V68 P51608 GPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGR 6c1y B 2.30 BS02 NUC E 1 R111 K112 S113 G114 R115 S116 D121 R20 K21 S22 G23 R24 S25 D30 P51608 GPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGR 6c2e A 2.15 BS02 NUC C 1 R166 K167 S168 G169 L170 S171 D176 K186 R188 R19 K20 S21 G22 L23 S24 D29 K39 R41 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c2f A 2.65 BS02 NUC C 1 R166 K167 S168 G169 L170 S171 K186 R188 R20 K21 S22 G23 L24 S25 K40 R42 Q9UBB5 GKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMP 6c2f J 2.65 BS02 NUC L 1 R166 K167 S168 G169 L170 S171 R188 R19 K20 S21 G22 L23 S24 R41 Q9UBB5 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMM 6c2k B 2.10 BS02 NUC F 1 R188 S189 K190 P191 R195 T210 R36 S37 K38 P39 R43 T58 Q9UBB5 PALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRT 6c42 A 2.00 BS01 85M A 1 L346 T347 L349 A350 D351 E353 W383 M388 F404 M421 I424 G521 H524 L525 V533 L34 T35 L37 A38 D39 E41 W71 M76 F92 M109 I112 G207 H210 L211 V219 P03372 TADQMVSALLDAEPPILYSEYDPPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPSYDLLLEMLDAHR 6c42 B 2.00 BS01 85M B 1 L346 T347 L349 A350 D351 E353 W383 M388 F404 I424 G521 H524 V533 L36 T37 L39 A40 D41 E43 W73 M78 F94 I112 G199 H202 V211 P03372 LALSLTADQMVSALLDAEPPILYSEYDPPFSMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVVPSYDLLLEMLDAH 6c46 A 1.95 BS01 CA A 1 E32 E36 E34 E38 5.1.3.13 A0A077ENB9 HHMKLVKTPLKDCYIIEPTVFEDERGYFYEKYNEKKFEELTGLNGHFVQDNISKSSYGVLRGLHLQKGKHAQAKLVSCLEGRVWDVAVDLRENSETFGKCYGMELSAENKLQFYVPRGFAHGFVVLSETAVFSYKCDNFYNKESEGSVKFNDSDLSIDWKIPEADMILSEKDQNAPAFKDKNY 6c8q A 2.58 BS01 NAD A 1 F133 N137 R141 F171 F172 T173 K174 A227 H261 K262 F132 N136 R140 F170 F171 T172 K173 A220 H254 K255 6.3.1.5 Q830Y9 TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKEDDKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q A 2.58 BS02 NAD B 1 Y34 H38 F40 Y148 G156 D181 Y33 H37 F39 Y147 G155 D180 6.3.1.5 Q830Y9 TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKEDDKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q B 2.58 BS01 NAD A 1 Y34 H38 Y148 G156 D181 Y34 H38 Y148 G156 D181 6.3.1.5 Q830Y9 MTTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q D 2.58 BS01 NAD D 1 F133 N137 R141 F171 F172 K174 H261 K262 F132 N136 R140 F170 F171 K173 H250 K251 6.3.1.5 Q830Y9 TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q D 2.58 BS02 NAD F 1 Y34 H38 L41 Y148 G156 D181 Y33 H37 L40 Y147 G155 D180 6.3.1.5 Q830Y9 TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q E 2.58 BS01 NAD E 1 F133 N137 R141 F171 F172 T173 K174 H261 K262 F133 N137 R141 F171 F172 T173 K174 H249 K250 6.3.1.5 Q830Y9 MTTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q F 2.58 BS01 NAD D 1 Y34 H38 F40 G156 A157 D181 Y34 H38 F40 G156 A157 D181 6.3.1.5 Q830Y9 MTTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q F 2.58 BS02 NAD F 1 F133 G136 N137 R141 F171 F172 T173 K174 H261 K262 F133 G136 N137 R141 F171 F172 T173 K174 H250 K251 6.3.1.5 Q830Y9 MTTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q G 2.58 BS02 NAD G 1 F133 N137 R141 E166 F171 F172 T173 K174 D177 D224 H261 K262 F132 N136 R140 E165 F170 F171 T172 K173 D176 D214 H251 K252 6.3.1.5 Q830Y9 TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8q H 2.58 BS01 NAD E 1 Y34 H38 G156 A157 D181 Y33 H37 G155 A156 D180 6.3.1.5 Q830Y9 TTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISGGQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALAFIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAVAGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKELGAPEALYLKIPKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQHKRHLPITIFDDFWK 6c8v A 3.20 BS01 FES A 1 W198 A199 Y200 C248 W252 C268 C323 R324 C325 W157 A158 Y159 C207 W211 C227 C282 R283 C284 P71517 VIPAPVGLLAELTHRCRSAELDTQTWLRVLTEAAGLGVLHVHLSGGEPTARPDIVEITAKCAELGLYSNLITSGVGGALAKLDALYDVGLDHVQLSVQGAQPQKMQFAARVTELGLPLTLNSVIHRGNIHEVPGFIDLAVKLGAKRLEVAHTQYYGWAYVNRAALMPDKSQVDESIRIVEAARERLKGQLVIDLVVPDYYAKYPKACAGGWGRKLMNVTPQGKVLPCHAAETIPGLEFWYVTDHALGEIWTKSPAFAAYRGTSWMKEPCRSCDRREKDWGGCRCQALALTGDAANTDPACSLSPLHAKMRDL 6c8v A 3.20 BS02 SF4 A 1 Y244 P245 C310 C313 R315 R316 D319 G321 T337 C341 L343 Y203 P204 C269 C272 R274 R275 D278 G280 T296 C300 L302 P71517 VIPAPVGLLAELTHRCRSAELDTQTWLRVLTEAAGLGVLHVHLSGGEPTARPDIVEITAKCAELGLYSNLITSGVGGALAKLDALYDVGLDHVQLSVQGAQPQKMQFAARVTELGLPLTLNSVIHRGNIHEVPGFIDLAVKLGAKRLEVAHTQYYGWAYVNRAALMPDKSQVDESIRIVEAARERLKGQLVIDLVVPDYYAKYPKACAGGWGRKLMNVTPQGKVLPCHAAETIPGLEFWYVTDHALGEIWTKSPAFAAYRGTSWMKEPCRSCDRREKDWGGCRCQALALTGDAANTDPACSLSPLHAKMRDL 6eih A 2.70 BS01 III P 1 R57 R130 Y131 L175 N176 V179 Y182 E183 N227 L230 W231 R55 R128 Y129 L173 N174 V177 Y180 E181 N225 L228 W229 P62258 DREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWT 6f08 A 1.90 BS01 III Q 1 N42 S45 V46 K49 R56 R60 R127 Y128 I166 L172 N173 V176 E180 D213 L220 D223 N224 L227 W228 N42 S45 V46 K49 R56 R60 R121 Y122 I160 L166 N167 V170 E174 D207 L214 D217 N218 L221 W222 P63104 29408703 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQASKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 6f08 I 1.90 BS01 III K 1 N42 S45 V46 K49 R56 R60 R127 Y128 G169 L172 N173 V176 E180 L216 L220 N224 L227 W228 N41 S44 V45 K48 R55 R59 R121 Y122 G162 L165 N166 V169 E173 L209 L213 N217 L220 W221 P63104 29408703 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 6f08 J 1.90 BS01 III N 1 S45 V46 K49 R56 R60 R127 Y128 L172 N173 V176 E180 L220 D223 N224 W228 S45 V46 K49 R56 R60 R124 Y125 L164 N165 V168 E172 L206 D209 N210 W214 P63104 29408703 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDYKDSTLIMQLLRDNLTLWTS 6f34 A 3.13 BS01 III C 1 G28 A29 F30 D31 M34 A181 R182 V186 A189 I190 A193 L197 A200 V201 H298 Q299 W301 V302 G28 A29 F30 D31 M34 A178 R179 V183 A186 I187 A190 L194 A197 V198 H295 Q296 W298 V299 Q5L1G5 MNLFRKKPIQLLMKESGAKGASLRKELGAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFILSGLACVFAALCYAEFASTVPVSGSAYTYSYATFGELIAWILGWDLILEYGVASSAVAVGWSGYFQGLLSGELPKALTSAYDPAKGTFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVVLLFLAVGVWYVKPENWTPFMPYGFSGVATGAATVFFAYIGFDAVSTAAEEVRNPQRDMPIGIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVAGFISLGAIAGITTVLLVSMYGQTRLFYAISRDGLLPKVFARISPTRQVPYVNTWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVSIGVLVLRKTQPDLKRAFRVPFVPVVPILAVLFCGYLVLQLPAMTWIGFVSWLLIGLVIYFIYGRKHSELN 6f34 A 3.13 BS02 ARG A 1 I40 G42 T43 G44 E115 Y116 A119 F231 A232 I234 V317 S321 T379 I40 G42 T43 G44 E115 Y116 A119 F228 A229 I231 V314 S318 T376 Q5L1G5 MNLFRKKPIQLLMKESGAKGASLRKELGAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFILSGLACVFAALCYAEFASTVPVSGSAYTYSYATFGELIAWILGWDLILEYGVASSAVAVGWSGYFQGLLSGELPKALTSAYDPAKGTFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVVLLFLAVGVWYVKPENWTPFMPYGFSGVATGAATVFFAYIGFDAVSTAAEEVRNPQRDMPIGIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVAGFISLGAIAGITTVLLVSMYGQTRLFYAISRDGLLPKVFARISPTRQVPYVNTWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVSIGVLVLRKTQPDLKRAFRVPFVPVVPILAVLFCGYLVLQLPAMTWIGFVSWLLIGLVIYFIYGRKHSELN 6f34 A 3.13 BS03 CLR A 1 V201 W204 Y205 V198 W201 Y202 Q5L1G5 MNLFRKKPIQLLMKESGAKGASLRKELGAFDLTMLGIGAIIGTGIFVLTGVAAAEHAGPALVLSFILSGLACVFAALCYAEFASTVPVSGSAYTYSYATFGELIAWILGWDLILEYGVASSAVAVGWSGYFQGLLSGELPKALTSAYDPAKGTFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVVLLFLAVGVWYVKPENWTPFMPYGFSGVATGAATVFFAYIGFDAVSTAAEEVRNPQRDMPIGIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVAGFISLGAIAGITTVLLVSMYGQTRLFYAISRDGLLPKVFARISPTRQVPYVNTWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVSIGVLVLRKTQPDLKRAFRVPFVPVVPILAVLFCGYLVLQLPAMTWIGFVSWLLIGLVIYFIYGRKHSELN 6f4w A 2.29 BS01 FMC A 1 M64 R87 T90 C91 G92 F159 E179 E181 S203 D204 L206 M64 R87 T90 C91 G92 F159 E179 E181 S203 D204 L206 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f4w A 2.29 BS02 FMC D 1 H4 R43 H4 R43 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f4w B 2.29 BS01 FMC B 1 R87 T90 C91 G92 F159 E179 M180 E181 S203 L206 R87 T90 C91 G92 F159 E179 M180 E181 S203 L206 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f4w C 2.29 BS01 FMC C 1 M64 R87 T90 C91 G92 F159 I178 E179 M180 E181 L206 M64 R87 T90 C91 G92 F159 I178 E179 M180 E181 L206 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f4x B 1.69 BS01 FMC B 1 M64 R87 T90 C91 G92 F159 E179 M180 E181 D204 L206 M64 R87 T90 C91 G92 F159 E179 M180 E181 D204 L206 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f4x C 1.69 BS01 FMC C 1 M64 R87 T90 C91 G92 F159 E179 M180 E181 S203 D204 M64 R87 T90 C91 G92 F159 E179 M180 E181 S203 D204 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f4x E 1.69 BS02 FMC E 1 M64 R87 T90 C91 G92 F159 I178 E179 M180 E181 S203 D204 L206 M64 R87 T90 C91 G92 F159 I178 E179 M180 E181 S203 D204 L206 2.4.2.1 P56463 MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGRGISLMGHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMAKYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMS 6f97 A 1.90 BS01 FAD A 1 G12 G14 T15 A16 I35 E36 A37 R60 W68 E90 G92 R93 L94 G97 G98 V101 N102 M103 V104 V105 S231 R232 V233 T265 A266 G267 Q270 W466 D500 A501 N511 T512 N513 T516 G8 G10 T11 A12 I31 E32 A33 R56 W64 E86 G88 R89 L90 G93 G94 V97 N98 M99 V100 V101 S227 R228 V229 T261 A262 G263 Q266 W457 D491 A492 N502 T503 N504 T507 1.1.3.47,1.8.3.- E4QP00 29384246 IFDYVIVGGGTAGSVLANRLSARPENRVLLIEAGIDTPENNIPPEIHDGLRPWLPRLSGDKFFWPNLTIHRAAEHPGITREPQFYEQGRLLGGGSSVNMVVSNRGLPRDYDEWQALGADGWDWQGVLPYFIKTERDADYGDDPLHGNAGPIPIGRVDSRHWSDFTVAATQALEAAGLPNIHDQNARFDDGYFPPAFTLKGEERFSAARGYLDASVRVRPNLSLWTESRVLKLLTTGNAITGVSVLRGRETLQVQAREVILTAGALQSPAILLRTGIGPAADLHALGIPVLADRPGVGRNLWEHSSIGVVAPLTEQARADASTGHQLGIRASSGVDPATPSDLFLHIGADPVSGLASAVFWVNKPSSTGWLKLKDADPFSYPDVDFNLLSDPRDLGRLKAGLRLITHYFAAPSLAKYGLALALSRFAAPQPGGPLLNDLLQDEAALERYLRTNVGGTWHASGTARIGRADDSQAVVDKAGRVYGVTGLRVADASIMPTVPTANTNLPTLMLAEKIADAILT 6f97 B 1.90 BS01 FAD B 1 G12 G14 T15 A16 I35 E36 A37 W68 E90 G92 R93 L94 G98 V104 V105 S231 V233 T265 A266 W466 D500 A501 N511 T512 N513 T516 G8 G10 T11 A12 I31 E32 A33 W41 E63 G65 R66 L67 G71 V73 V74 S195 V197 T229 A230 W424 D458 A459 N469 T470 N471 T474 1.1.3.47,1.8.3.- E4QP00 29384246 IFDYVIVGGGTAGSVLANRLSARPENRVLLIEAGIDTKFFWPNLTIHRAAEHPGITREPQFYEQGRLLGGGSVVSNRGLPRDYDEWQALGADGWDWQGVLPYFIKTERDADYGDDPLHGNAGPIPIGRVDSRHWSDFTVAATQALEAAGLPNIHDQNARFDDGYFPPAFTLKSAARGYLDASVRVRPNLSLWTESRVLKLLTTGNAITGVSVLRGRETLQVQAREVILTAGALQSPAILLRTGIGPAADLHALGIPVLADRPGVGRNLWEHSSIGVVAPLTEQARADASTHQLGIRASSGVDPATPSDLFLHIGADPVSGLASAVFWVNKPSSTGWLKLKDADPFSYPDVDFNLLSDPRDLGRLKAGLRLITHYFAAPSLAKYGLALALSRFAAPQPGGPLLNDLLQDEAALERYLRTNVGGTWHASGTARIGRADDSQAVVDKAGRVYGVTGLRVADASIMPTVPTANTNLPTLMLAEKIADAILT 6ffx A 2.50 BS03 NAD A 1 C38 H39 S40 H43 D153 T157 V180 G181 G182 L183 D203 L204 R208 S223 F246 V247 T252 V269 G270 I271 P293 Y294 W295 R340 C38 H39 S40 H43 D153 T157 V180 G181 G182 L183 D203 L204 R208 S223 F246 V247 T252 V269 G270 I271 P293 Y294 W295 R340 A0A1Q8I6M1 29384657 MKAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDIHVMDMPAAQYAYGLPLTLGHEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGLGSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKSGAGAADAIRELTGGQGATAVFDFVGAQSTIDTAQQVVAVDGHISVVGIHAGAHAKVGFFMIPFGASVVTPYWGTRSELMEVVALARAGRLDIHTETFTLDEGPAAYRRLREGSIRGRGVVVPT