5o9a A 1.78 BS01 7M6 A 1 K104 P105 F106 M107 S108 L239 S242 K104 P105 F106 M107 S108 L239 S242 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a A 1.78 BS02 GLU A 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a A 1.78 BS03 7M6 B 1 P105 S108 S217 K218 G219 P105 S108 S217 K218 G219 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a B 1.78 BS01 7M6 A 1 P105 S108 S217 K218 G219 P105 S108 S217 K218 G219 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGSG 5o9a B 1.78 BS02 7M6 B 1 K104 P105 F106 M107 L239 S242 K104 P105 F106 M107 L239 S242 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGSG 5o9a B 1.78 BS03 GLU B 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGSG 5o9a C 1.78 BS01 7M6 C 1 K104 P105 F106 M107 S108 L239 S242 K104 P105 F106 M107 S108 L239 S242 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a C 1.78 BS02 CIT C 1 R148 R149 S150 K151 D156 R148 R149 S150 K151 D156 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a C 1.78 BS03 GLU C 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a C 1.78 BS04 7M6 D 1 P105 S108 S217 K218 G219 P105 S108 S217 K218 G219 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGECGS 5o9a D 1.78 BS01 7M6 C 1 P105 S108 S217 K218 G219 P104 S107 S216 K217 G218 29256599 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGEC 5o9a D 1.78 BS02 7M6 D 1 K104 P105 F106 M107 S242 K103 P104 F105 M106 S241 29256599 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGEC 5o9a D 1.78 BS03 GLU D 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y220 Y60 P88 L89 T90 R95 L137 G140 S141 T142 E192 Y219 29256599 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKNKWWYDKGEC 5oay A BS01 SF4 A 1 H5 V8 C9 C37 C40 P41 T43 C46 G61 G62 H5 V8 C9 C37 C40 P41 T43 C46 G61 G62 29273788 MDWRHKAVCRDEDPELFFPVGNSGPALAQIADAKLVCNRCPVTTECLSWALNTGQDSGVWGGMSEDERRALKRRNA 5oew A 2.00 BS01 GLU A 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew A 2.00 BS02 ZN A 1 E42 H46 E42 H46 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew A 2.00 BS03 9TE B 1 K104 P105 F106 M107 S108 K218 N242 L247 K104 P105 F106 M107 S108 K218 N242 L247 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew B 2.00 BS01 9TE B 1 P105 F106 M107 S108 S217 K218 G219 N242 P103 F104 M105 S106 S215 K216 G217 N240 29256599 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew B 2.00 BS02 GLU B 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y59 P87 L88 T89 R94 L136 G139 S140 T141 E191 29256599 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew B 2.00 BS03 ZN B 1 E42 K45 H46 E40 K43 H44 29256599 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew C 2.00 BS01 9TE C 1 K104 P105 F106 M107 K218 N242 L247 K104 P105 F106 M107 K218 N242 L247 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew C 2.00 BS02 GLU C 1 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 Y61 P89 L90 T91 R96 L138 G141 S142 T143 E193 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew C 2.00 BS03 ZN C 1 H23 E30 H23 E30 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5oew C 2.00 BS04 ZN C 2 E42 H46 E42 H46 29256599 GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5ohi A 1.66 BS01 ZN A 1 D311 H315 H474 D261 H265 H416 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5ohi A 1.66 BS02 ZN A 2 D171 T209 D358 H359 D121 T159 D308 H309 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5ohi A 1.66 BS03 CA A 1 D735 N737 N739 L741 R742 D743 D658 N660 N662 L664 R665 D666 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5ohi A 1.66 BS04 9V8 A 1 I167 D171 T209 F210 L213 Y214 L216 A217 N230 L243 W260 F273 F274 W275 Y306 D311 H315 H474 I117 D121 T159 F160 L163 Y164 L166 A167 N180 L193 W210 F223 F224 W225 Y256 D261 H265 H416 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5ohx A 3.20 BS01 HEM A 1 R8 S10 Y11 C12 T13 W14 A18 N20 S21 P22 H23 P185 P188 L189 Y192 G222 R225 V272 R4 S6 Y7 C8 T9 W10 A14 N16 S17 P18 H19 P181 P184 L185 Y188 G218 R221 V265 29275181 QPNRPSYCTWELNATNSPHTCRTKNGDYTKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDEVGFYEVEGIGYDFIPTVLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEEKRMVIILPDGIRNYLTKFVSEYWMETRGFLQPVCQNEMNKWWWNMKISNLSFDKQSLLKENTVTCQEAMHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVISGIVKCTDFVDKAMVKQYVKVKHSATLGYISRVLEKEPYVIILDDEHDDAFIGIVNQFHILQFITKN 5ohx A 3.20 BS02 PLP A 1 K78 N108 G213 A214 G215 T216 G217 G218 T219 G263 I264 S307 P333 D334 K74 N104 G209 A210 G211 T212 G213 G214 T215 G256 I257 S300 P326 D327 29275181 QPNRPSYCTWELNATNSPHTCRTKNGDYTKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDEVGFYEVEGIGYDFIPTVLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEEKRMVIILPDGIRNYLTKFVSEYWMETRGFLQPVCQNEMNKWWWNMKISNLSFDKQSLLKENTVTCQEAMHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVISGIVKCTDFVDKAMVKQYVKVKHSATLGYISRVLEKEPYVIILDDEHDDAFIGIVNQFHILQFITKN 5ohx B 3.20 BS01 HEM B 1 R8 S10 Y11 C12 T13 W14 A18 N20 S21 P22 H23 P185 P188 L189 Y192 R225 V272 R4 S6 Y7 C8 T9 W10 A14 N16 S17 P18 H19 P181 P184 L185 Y188 R221 V265 29275181 QPNRPSYCTWELNATNSPHTCRTKNGDYTKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDEVGFYEVEGIGYDFIPTVLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEEKRMVIILPDGIRNYLTKFVSEYWMETRGFLQPVCQNEMNKWWWNMKISNLSFDKQSLLKENTVTCQEAMHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVISGIVKCTDFVDKAMVKQYVKVKHSATLGYISRVLEKEPYVIILDDEHDDAFIGIVNQFHILQFITKN 5ohx B 3.20 BS02 PLP B 1 K78 N108 G213 A214 G215 T216 G217 G218 T219 G263 I264 S307 P333 D334 K74 N104 G209 A210 G211 T212 G213 G214 T215 G256 I257 S300 P326 D327 29275181 QPNRPSYCTWELNATNSPHTCRTKNGDYTKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDEVGFYEVEGIGYDFIPTVLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEEKRMVIILPDGIRNYLTKFVSEYWMETRGFLQPVCQNEMNKWWWNMKISNLSFDKQSLLKENTVTCQEAMHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVISGIVKCTDFVDKAMVKQYVKVKHSATLGYISRVLEKEPYVIILDDEHDDAFIGIVNQFHILQFITKN 5olb A 1.82 BS01 ZN A 1 D311 H315 H474 D261 H265 H417 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5olb A 1.82 BS02 ZN A 2 D171 T209 D358 H359 D121 T159 D308 H309 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5olb A 1.82 BS03 CA A 1 D735 N737 N739 L741 R742 D743 D665 N667 N669 L671 R672 D673 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5olb A 1.82 BS04 6ZO A 1 I167 S169 D171 T209 L213 A217 L243 W260 F273 F274 W275 Y306 D311 H315 H474 I117 S119 D121 T159 L163 A167 L193 W210 F223 F224 W225 Y256 D261 H265 H417 3.1.4.39 29259743 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5omj A 2.01 BS01 FE A 1 E69 E102 H105 E202 E68 E101 H104 E200 1.17.4.1 29268610 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRT 5omj A 2.01 BS02 FE A 2 E102 Y162 E202 H205 E101 Y161 E200 H203 1.17.4.1 29268610 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRT 5omk A 1.70 BS01 FE A 1 F98 E102 E167 E202 H205 F97 E101 E166 E201 H204 1.17.4.1 29268610 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRT 5omk A 1.70 BS02 FE A 2 E69 E102 H105 E202 E68 E101 H104 E201 1.17.4.1 29268610 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRT 5uci A 2.70 BS01 874 A 1 L43 N46 A47 D49 A50 K53 L86 D88 I91 G92 M93 L102 F133 T179 V181 L45 N48 A49 D51 A52 K55 L88 D90 I93 G94 M95 L104 F135 T181 V183 GHMPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYL 5uci B 2.70 BS01 874 B 1 L43 N46 A47 D49 A50 D88 I91 M93 F133 T179 V181 L34 N37 A38 D40 A41 D79 I82 M84 F124 T170 V172 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYL 5uci C 2.70 BS01 874 C 1 L43 N46 A47 D49 A50 K53 L86 D88 I91 G92 M93 F133 V145 T179 V181 L43 N46 A47 D49 A50 K53 L86 D88 I91 G92 M93 F133 V145 T179 V181 HMPEEVHHGEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYL 5uci D 2.70 BS01 874 D 1 L43 N46 A47 A50 K53 L86 D88 M93 L102 F133 T179 V181 L34 N37 A38 A41 K44 L77 D79 M84 L93 F124 T170 V172 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYL 5w2r A 2.90 BS01 MNB A 1 C34 F35 K36 C14 F15 K16 29232505 MKEYTLDKAHTDVCFKIKHLQISNVKGNFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLNIEVEANEKE 5w2v A 2.90 BS01 SEC A 1 D32 C34 D12 C14 29232505 MKEYTLDKAHTDVCFKIKHLQISNVKGNFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLNIEVEANEKE 5w2z A 2.80 BS01 MNB A 1 K46 C48 N78 E80 K26 C28 N58 E60 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGCFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLNIEVEANEKE 5w30 A 2.75 BS01 9UM A 1 K46 G47 C48 N78 E80 K26 G27 C28 N58 E60 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGCFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLNIEVEANEKE 5w31 A 2.56 BS01 MBO A 1 K46 G47 C48 E80 K26 G27 C28 E60 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGCFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLNIEVEANEKE 5w39 A 2.48 BS01 9UM A 1 E137 S154 N156 C182 E117 S134 N136 C162 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGNFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLCIEVEANEKE 5w3a A 2.76 BS01 MNB A 1 S154 N156 C182 S134 N136 C162 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGNFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLCIEVEANEKE 5w3b A 2.70 BS01 MBO A 1 N156 G157 N180 L181 C182 N136 G137 N160 L161 C162 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGNFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLCIEVEANEKE 5w3c A 2.87 BS01 SEC A 1 N156 C182 N136 C162 29232505 MKEYTLDKAHTDVGFKIKHLQISNVKGNFKDYSAVIDFDPASAEFKKLDVTIKIASVNTENQTRDNHLQQDDFFKAKKYPDMTFTMKKYEKIDNEKGKMTGTLTIAGVSKDIVLDAEIGGVAKGKDGKEKIGFSLNGKIKRSDFKFATSTSTITLSDDINLCIEVEANEKE 5w78 B 2.27 BS01 CA B 1 D205 N207 D208 D210 E211 V213 D36 N38 D39 D41 E42 V44 3.1.1.77 DICSLPVLAKICQKIKLAMEQSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDSAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w78 B 2.27 BS02 CA B 2 D223 D227 N229 N231 I233 E245 D54 D58 N60 N62 I64 E76 3.1.1.77 DICSLPVLAKICQKIKLAMEQSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDSAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7a B 2.30 BS01 CA B 1 D183 D185 D187 Y189 D204 D207 D15 D17 D19 Y21 D36 D39 3.1.1.77 QKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7a B 2.30 BS02 CA B 2 D185 D187 D204 N206 D207 D209 V212 D17 D19 D36 N38 D39 D41 V44 3.1.1.77 QKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7a B 2.30 BS03 CA B 3 D222 D226 N228 N230 I232 E244 D54 D58 N60 N62 I64 E76 3.1.1.77 QKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b A 1.90 BS01 FUC A 1 Q55 V56 N58 Q20 V21 N23 3.1.1.77 DHYTCVGCVLVVSVIEQLAQVHNSTVQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQPLCHLYPLPK 5w7b C 1.90 BS01 PA1 A 1 G340 N372 R378 G178 N210 R216 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSAENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b C 1.90 BS02 CA C 1 D183 D185 D187 Y189 D204 D207 D25 D27 D29 Y31 D46 D49 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSAENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b C 1.90 BS03 CA C 2 D185 D187 D204 N206 D207 D209 V212 D27 D29 D46 N48 D49 D51 V54 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSAENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b C 1.90 BS04 CA C 3 D222 D226 N228 N230 I232 E244 D64 D68 N70 N72 I74 E86 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSAENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b C 1.90 BS05 FUC C 1 D209 R225 D51 R67 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSAENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b B 1.90 BS01 FUC B 1 Q55 V56 N58 Q20 V21 N23 3.1.1.77 DHYTCVGCVLVVSVIEQLAQVHNSTVQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQPLCHLYPLP 5w7b D 1.90 BS01 PA1 B 1 G340 N372 R378 G177 N209 R215 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b D 1.90 BS02 CA D 1 D183 D185 D187 Y189 D204 D207 D25 D27 D29 Y31 D46 D49 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b D 1.90 BS03 CA D 2 D185 D187 D204 N206 D207 D209 V212 D27 D29 D46 N48 D49 D51 V54 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b D 1.90 BS04 CA D 3 D222 D226 N228 N230 I232 E244 D64 D68 N70 N72 I74 E86 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7b D 1.90 BS05 FUC D 1 D209 R225 D51 R67 3.1.1.77 CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 5w7c C 2.23 BS01 CA C 1 D184 D186 D188 Y190 D205 D208 D29 D31 D33 Y35 D50 D53 3.1.1.77 GSDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDAAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7c C 2.23 BS02 CA C 2 D186 D188 D205 N207 D208 D210 V213 D31 D33 D50 N52 D53 D55 V58 3.1.1.77 GSDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDAAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7c C 2.23 BS03 CA C 3 D223 D227 N229 N231 I233 E245 D68 D72 N74 N76 I78 E90 3.1.1.77 GSDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDAAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7c D 2.23 BS01 CA D 1 D184 D186 D188 Y190 D205 D208 D28 D30 D32 Y34 D49 D52 3.1.1.77 SDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDAAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7c D 2.23 BS02 CA D 2 D186 D188 D205 N207 D208 D210 V213 D30 D32 D49 N51 D52 D54 V57 3.1.1.77 SDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDAAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7c D 2.23 BS03 CA D 3 D223 D227 N229 N231 I233 E245 D67 D71 N73 N75 I77 E89 3.1.1.77 SDICSLPVLAKICQKIKLAMEQSVPFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDAAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYAMIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLPDGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 5w7d A 1.75 BS01 CA A 1 D183 D185 D187 H189 D204 D207 D137 D139 D141 H143 D158 D161 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRSCSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7d A 1.75 BS02 CA A 2 D185 D187 D204 N206 D207 D209 V212 D139 D141 D158 N160 D161 D163 V166 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRSCSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7d A 1.75 BS03 CA A 3 D222 D226 N228 N230 I232 E244 D176 D180 N182 N184 I186 E198 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRSCSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e A 1.83 BS01 CA A 1 D183 D185 D187 H189 D204 D207 D130 D132 D134 H136 D151 D154 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e A 1.83 BS02 CA A 2 D185 D187 D204 N206 D207 D209 V212 D132 D134 D151 N153 D154 D156 V159 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e A 1.83 BS03 CA A 3 D222 D226 N228 N230 I232 E244 D169 D173 N175 N177 I179 E191 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e A 1.83 BS04 FAW A 1 L41 D261 A262 A263 I269 G340 I370 N372 P418 G420 F422 L423 F446 P457 F504 V525 D526 F528 H529 P530 L7 D208 A209 A210 I216 G287 I317 N319 P365 G367 F369 L370 F393 P404 F451 V472 D473 F475 H476 P477 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e B 1.83 BS01 CA B 1 D183 D185 D187 H189 D204 D207 D135 D137 D139 H141 D156 D159 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e B 1.83 BS02 CA B 2 D185 D187 D204 N206 D207 D209 V212 D137 D139 D156 N158 D159 D161 V164 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e B 1.83 BS03 CA B 3 D222 D226 N228 N230 I232 E244 D174 D178 N180 N182 I184 E196 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7e B 1.83 BS04 FAW B 1 L41 D261 A262 A263 F267 I269 L274 G340 I370 G371 N372 P418 G420 F446 P457 F504 I522 V525 D526 F528 H529 P530 L7 D213 A214 A215 F219 I221 L226 G292 I322 G323 N324 P370 G372 F398 P409 F456 I474 V477 D478 F480 H481 P482 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7f A 2.80 BS01 CA A 1 D183 D185 D187 H189 D204 D207 D131 D133 D135 H137 D152 D155 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7f A 2.80 BS02 CA A 2 D185 D187 D204 N206 D207 D209 V212 D133 D135 D152 N154 D155 D157 V160 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7f A 2.80 BS03 CA A 3 D222 D226 N228 N230 I232 E244 D170 D174 N176 N178 I180 E192 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRQCHLYPLPQEAWESALEKARQVLRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7f B 2.80 BS01 CA B 1 D183 D185 D187 H189 D204 D207 D137 D139 D141 H143 D158 D161 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7f B 2.80 BS02 CA B 2 D185 D187 D204 N206 D207 D209 V212 D139 D141 D158 N160 D161 D163 V166 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5w7f B 2.80 BS03 CA B 3 D222 D226 N228 N230 I232 E244 D176 D180 N182 N184 I186 E198 3.1.1.77 SHGQSCLGCVVLVSVIEQLAEVHNSSVQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQPQCHLYPLPQEAWESALEKARQVLRRICSLPFLTKICQKIELSIKKAVPFKDVDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQLSGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASDHPAIVLYAMIGNDVCNSKADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPDGTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQLSNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQANRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 5wa7 A 2.20 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wa7 A 2.20 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wa7 A 2.20 BS03 KU4 A 1 A20 M21 Y24 E26 K34 I38 H41 D108 E119 I120 Y130 A24 M25 Y28 E30 K38 I42 H45 D93 E104 I105 Y115 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wap A 2.20 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wap A 2.20 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wap A 2.20 BS03 KU9 A 1 Y24 I38 H41 E80 D108 E119 I120 Y28 I42 H45 E65 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wb3 A 2.20 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wb3 A 2.20 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wb3 A 2.20 BS03 GYA A 1 A20 Y24 E26 K34 I38 H41 E80 D108 E119 I120 A24 Y28 E30 K38 I42 H45 E65 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wcs A 2.53 BS01 MN A 1 H41 E80 D108 H41 E61 D89 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5wcs A 2.53 BS02 MN A 2 H41 D108 E119 I120 H41 D89 E100 I101 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5wcs A 2.53 BS03 9KU A 1 A20 M21 Y24 E26 K34 I38 H41 E80 D108 E119 I120 Y130 K134 A20 M21 Y24 E26 K34 I38 H41 E61 D89 E100 I101 Y111 K115 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5wct A 2.30 BS01 MN A 1 H41 D108 E119 I120 H41 D89 E100 I101 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5wct A 2.30 BS02 MN A 2 H41 E80 D108 H41 E61 D89 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5wct A 2.30 BS03 GY4 A 1 A20 M21 Y24 E26 K34 I38 H41 E80 D108 E119 I120 Y130 K134 A20 M21 Y24 E26 K34 I38 H41 E61 D89 E100 I101 Y111 K115 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5wdc A 2.10 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKISEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdc A 2.10 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKISEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdc A 2.10 BS03 G2K A 1 A20 Y24 E26 K34 I38 H41 E80 D108 E119 I120 A24 Y28 E30 K38 I42 H45 E65 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKISEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdn A 2.10 BS01 MN A 1 H41 D108 E119 I120 H41 D89 E100 I101 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdn A 2.10 BS02 MN A 2 H41 E80 D108 H41 E61 D89 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdn A 2.10 BS03 G1K A 1 M21 Y24 E26 K34 I38 H41 E80 R84 D108 E119 I120 Y130 K134 M21 Y24 E26 K34 I38 H41 E61 R65 D89 E100 I101 Y111 K115 29215062 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdw A 2.30 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdw A 2.30 BS02 MN A 2 H41 E80 P107 D108 H45 E65 P92 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wdw A 2.30 BS03 8KU A 1 Y24 K34 A37 I38 H41 E80 D108 E119 I120 Y28 K38 A41 I42 H45 E65 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5we7 A 2.12 BS01 MN A 1 H41 D108 E119 I120 H41 D89 E100 I101 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERAAAELA 5we7 A 2.12 BS02 MN A 2 H41 E80 D108 H41 E61 D89 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERAAAELA 5we7 A 2.12 BS03 G3K A 1 A37 H41 E80 R84 D108 E119 I120 R124 Y130 K134 A37 H41 E61 R65 D89 E100 I101 R105 Y111 K115 MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSERAAAELA 5web A 2.25 BS01 MN A 1 H41 D108 E119 I120 H45 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5web A 2.25 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5web A 2.25 BS03 KU5 A 1 A20 Y24 E26 K34 I38 H41 E80 L106 D108 E119 I120 A24 Y28 E30 K38 I42 H45 E65 L91 D93 E104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wf3 A 2.25 BS01 MN A 1 H41 D108 D119 I120 H45 D93 D104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wf3 A 2.25 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wf3 A 2.25 BS03 KU2 A 1 Y24 I38 H41 E80 D108 D119 I120 Y130 Y28 I42 H45 E65 D93 D104 I105 Y115 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfm A 2.25 BS01 MN A 1 H41 D108 D119 I120 H44 D92 D103 I104 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfm A 2.25 BS02 MN A 2 H41 E80 D108 H44 E64 D92 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfm A 2.25 BS03 KU5 A 1 Y24 K34 I38 H41 E80 F105 L106 D108 D119 I120 Y27 K37 I41 H44 E64 F89 L90 D92 D103 I104 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfw A 2.29 BS01 MN A 1 H41 D108 D119 I120 H45 D93 D104 I105 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfw A 2.29 BS02 MN A 2 H41 E80 D108 H45 E65 D93 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wfw A 2.29 BS03 GYA A 1 A20 Y24 E26 K34 I38 H41 E80 D108 D119 I120 K134 A24 Y28 E30 K38 I42 H45 E65 D93 D104 I105 K119 29215062 RGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wg9 A 2.30 BS01 MN A 1 H41 D108 D119 I120 H44 D92 D103 I104 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wg9 A 2.30 BS02 MN A 2 H41 E80 D108 H44 E64 D92 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wg9 A 2.30 BS03 KU4 A 1 A20 Y24 I38 H41 E80 D108 D119 I120 Y130 K134 A23 Y27 I41 H44 E64 D92 D103 I104 Y114 K118 29215062 GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 5wha A 2.04 BS01 GDP A 1 V12 G13 V14 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 N103 K104 D106 L107 S132 A133 K134 TEYKLVVVGAVGVGKSALTIQLIQNSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha A 2.04 BS02 CA A 1 E63 Y64 E50 Y51 TEYKLVVVGAVGVGKSALTIQLIQNSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha D 2.04 BS01 III E 1 E3 K5 V7 D38 Y40 R41 I55 L56 D57 T58 A59 E62 E63 R68 Y71 T74 E3 K5 V7 D30 Y32 R33 I47 L48 D49 T50 A51 E54 E55 R60 Y63 T66 MTEYKLVVVGAVGVGKSALTIQLIQNHFEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha D 2.04 BS02 GDP D 1 V12 G13 V14 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V12 G13 V14 G15 K16 S17 A18 F28 N108 K109 D111 L112 S132 A133 K134 MTEYKLVVVGAVGVGKSALTIQLIQNHFEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha D 2.04 BS03 CA D 1 E63 Y64 E55 Y56 MTEYKLVVVGAVGVGKSALTIQLIQNHFEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha G 2.04 BS01 GDP G 1 V12 G13 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V11 G12 G14 K15 S16 A17 F27 N112 K113 D115 L116 S141 A142 K143 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha G 2.04 BS02 CA G 1 E63 Y64 E59 Y60 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wha I 2.04 BS01 CA I 1 D16 E19 D14 E17 RRPRCPGDDASIEDLHEYWARLWNYLYAVA 5wha J 2.04 BS01 III K 1 E3 K5 V7 S39 Y40 R41 D54 I55 L56 D57 T58 E63 R68 Y71 M72 E2 K4 V6 S25 Y26 R27 D40 I41 L42 D43 T44 E49 R54 Y57 M58 TEYKLVVVGAVGVGKSALTIQLIQSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRK 5wha J 2.04 BS02 GDP J 1 V12 G13 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 V11 G12 G14 K15 S16 A17 N102 K103 D105 L106 S131 A132 K133 TEYKLVVVGAVGVGKSALTIQLIQSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRK 5whb A 2.18 BS01 GDP A 1 G13 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 G13 G15 K16 S17 A18 F28 N110 K111 D113 L114 S139 A140 K141 MTEYKLVVVGAVGVGKSALTIQLIQNHFVIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb A 2.18 BS02 CA A 1 E63 Y64 E57 Y58 MTEYKLVVVGAVGVGKSALTIQLIQNHFVIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb C 2.18 BS01 CA C 1 D16 E19 D15 E18 PRRPRCPGDDASIEDLHEYWARLWNYLYRVA 5whb D 2.18 BS01 GDP D 1 V12 G13 V14 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 V12 G13 V14 G15 K16 S17 A18 N108 K109 D111 L112 S137 A138 K139 MTEYKLVVVGAVGVGKSALTIQLIQNHFVDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb D 2.18 BS02 CA D 1 E63 Y64 E55 Y56 MTEYKLVVVGAVGVGKSALTIQLIQNHFVDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb F 2.18 BS01 CA F 1 D16 E19 D15 E18 PRRPRCPGDDASIEDLHEYWARLWNYLYRVA 5whb G 2.18 BS01 III H 1 E3 K5 D38 Y40 R41 I55 L56 D57 T58 A59 E63 R68 Y71 T74 E2 K4 D30 Y32 R33 I47 L48 D49 T50 A51 E55 R60 Y63 T66 TEYKLVVVGAVGVGKSALTIQLIQNHFVEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb G 2.18 BS02 GDP G 1 V12 G13 V14 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 F27 N108 K109 D111 L112 S137 A138 K139 TEYKLVVVGAVGVGKSALTIQLIQNHFVEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb G 2.18 BS03 MG G 1 S17 D57 T58 S16 D49 T50 TEYKLVVVGAVGVGKSALTIQLIQNHFVEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb J 2.18 BS01 III K 1 E3 K5 D38 Y40 R41 I55 L56 D57 T58 A59 E63 S65 R68 Y71 M72 T74 E3 K5 D29 Y31 R32 I46 L47 D48 T49 A50 E54 S56 R59 Y62 M63 T65 MTEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb J 2.18 BS02 GDP J 1 V12 G13 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V12 G13 G15 K16 S17 A18 F28 N107 K108 D110 L111 S136 A137 K138 MTEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb J 2.18 BS03 CA J 1 E3 R41 D54 E3 R32 D45 MTEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whb L 2.18 BS01 CA J 2 W25 L28 W24 L27 PRRPRCPGDDASIEDLHEYWARLWNYLYRVA 5whd A 1.64 BS01 GDP A 1 G13 V14 G15 K16 S17 A18 F28 A59 N116 K117 D119 L120 S145 A146 K147 G13 V14 G15 K16 S17 A18 F28 A59 N116 K117 D119 L120 S145 A146 K147 MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRK 5whd B 1.64 BS01 GDP B 1 V12 G13 G15 K16 S17 A18 F28 A59 N116 K117 D119 L120 S145 A146 K147 V12 G13 G15 K16 S17 A18 F28 A55 N112 K113 D115 L116 S141 A142 K143 MTEYKLVVVGAVGVGKSALTIQLIQNHFVPTIEPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whd C 1.64 BS01 GDP C 1 V12 G13 G15 K16 S17 A18 F28 A59 N116 K117 D119 L120 S145 A146 V12 G13 G15 K16 S17 A18 F28 A50 N107 K108 D110 L111 S136 A137 MTEYKLVVVGAVGVGKSALTIQLIQNHFPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whd D 1.64 BS01 GDP D 1 V12 G13 G15 K16 S17 A18 A59 N116 K117 D119 L120 S145 A146 V12 G13 G15 K16 S17 A18 A48 N105 K106 D108 L109 S134 A135 MTEYKLVVVGAVGVGKSALTIQLIQEPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe A 1.91 BS01 GNP A 1 V12 G13 V14 G15 K16 S17 A18 F28 G60 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 F27 G57 N113 K114 D116 L117 S142 A143 K144 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPEPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe A 1.91 BS02 CA A 1 E63 Y64 S65 E60 Y61 S62 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPEPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe D 1.91 BS01 GNP D 1 V12 G13 V14 G15 K16 S17 A18 F28 G60 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 F27 G51 N107 K108 D110 L111 S136 A137 K138 TEYKLVVVGAVGVGKSALTIQLIQNHFVPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe D 1.91 BS02 CA D 1 E63 Y64 S65 E54 Y55 S56 TEYKLVVVGAVGVGKSALTIQLIQNHFVPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe G 1.91 BS01 GNP G 1 V12 G13 V14 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 N104 K105 D107 L108 S133 A134 K135 TEYKLVVVGAVGVGKSALTIQLIQNPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe G 1.91 BS02 CA G 1 E63 Y64 E51 Y52 TEYKLVVVGAVGVGKSALTIQLIQNPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe J 1.91 BS01 GNP J 1 V12 G13 V14 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V12 G13 V14 G15 K16 S17 A18 F28 N107 K108 D110 L111 S136 A137 K138 MTEYKLVVVGAVGVGKSALTIQLIQNHFPSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5whe F 1.91 BS01 CA F 1 D16 E19 D15 E18 PRRPRCPGDDASIEDLHEYWARLWNYLYAVA 5wlb A 1.72 BS01 GNP A 1 V12 G13 V14 G15 K16 S17 A18 F28 D30 G60 N116 K117 D119 S145 A146 K147 V12 G13 V14 G15 K16 S17 A18 F28 D30 G53 N109 K110 D112 S138 A139 K140 MTEYKLVVVGAVGVGKSALTIQLIQNHFVDDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wlb D 1.72 BS01 GNP D 1 V12 G13 V14 G15 K16 S17 A18 F28 G60 N116 K117 D119 L120 S145 A146 V12 G13 V14 G15 K16 S17 A18 F28 G57 N113 K114 D116 L117 S142 A143 MTEYKLVVVGAVGVGKSALTIQLIQNHFVDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKH 5wpl A 2.15 BS01 III B 1 E3 K5 T35 E37 D38 S39 Y40 R41 D54 I55 L56 D57 T58 A59 E63 R68 Y71 T74 E2 K4 T34 E36 D37 S38 Y39 R40 D53 I54 L55 D56 T57 A58 E62 R67 Y70 T73 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl A 2.15 BS02 GNP A 1 V12 G13 V14 G15 K16 S17 A18 F28 G60 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 F27 G59 N115 K116 D118 L119 S144 A145 K146 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl A 2.15 BS03 CA A 1 E63 Y64 S65 E62 Y63 S64 TEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl D 2.15 BS01 III E 1 E3 K5 L6 D38 S39 Y40 R41 D54 I55 L56 D57 T58 A59 E63 S65 R68 Y71 M72 T74 E2 K4 L5 D28 S29 Y30 R31 D44 I45 L46 D47 T48 A49 E53 S55 R58 Y61 M62 T64 TEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl D 2.15 BS02 GNP D 1 V12 G13 V14 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 F27 N106 K107 D109 L110 S135 A136 K137 TEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl G 2.15 BS01 III H 1 E3 K5 D38 S39 Y40 R41 D54 I55 L56 D57 T58 A59 E63 R68 Y71 E2 K4 D26 S27 Y28 R29 D42 I43 L44 D45 T46 A47 E51 R56 Y59 TEYKLVVVGAVGVGKSALTIQLIQNDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRK 5wpl G 2.15 BS02 GNP G 1 V12 G13 V14 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 N104 K105 D107 L108 S133 A134 K135 TEYKLVVVGAVGVGKSALTIQLIQNDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRK 5wpl G 2.15 BS03 CA G 1 E63 Y64 S65 E51 Y52 S53 TEYKLVVVGAVGVGKSALTIQLIQNDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRK 5wpl J 2.15 BS01 III K 1 E3 K5 L6 D38 S39 Y40 R41 D54 I55 L56 D57 T58 A59 E63 S65 R68 Y71 M72 E2 K4 L5 D28 S29 Y30 R31 D44 I45 L46 D47 T48 A49 E53 S55 R58 Y61 M62 TEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl J 2.15 BS02 GNP J 1 V12 G13 V14 G15 K16 S17 A18 F28 N116 K117 D119 L120 S145 A146 K147 V11 G12 V13 G14 K15 S16 A17 F27 N106 K107 D109 L110 S135 A136 K137 TEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl J 2.15 BS03 CA J 1 E63 Y64 S65 E53 Y54 S55 TEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPSRTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRKH 5wpl L 2.15 BS01 CA L 1 D16 E19 D15 E18 PRRPRCPGDDASIEDLHEYWARLWNYLYAVA 5wpm A 1.72 BS01 GNP A 1 V12 G13 V14 G15 K16 S17 A18 F28 G60 Q61 N116 K117 D119 L120 S145 A146 K147 V12 G13 V14 G15 K16 S17 A18 F28 G51 Q52 N105 K106 D108 L109 S134 A135 K136 MTEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIR 5wpm A 1.72 BS02 MG A 1 G10 A11 V81 F82 S89 I93 G10 A11 V72 F73 S80 I84 MTEYKLVVVGAVGVGKSALTIQLIQNHFDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIR 5wvd A 3.00 BS01 7UX A 1 E53 L55 V63 A76 L108 F124 E125 K126 L127 Q128 G129 G130 L177 C190 D191 F192 E13 L15 V23 A36 L68 F84 E85 K86 L87 Q88 G89 G90 L137 C150 D151 F152 PGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ 5wvd B 3.00 BS01 7UX B 1 L55 V63 A76 L108 F124 L127 Q128 G129 G130 L177 C190 D191 F192 L15 V23 A36 L68 F84 L87 Q88 G89 G90 L128 C139 D140 F141 PGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQASRVVRDVAAALDFLHTKGIAHRDLKPENILCESPVSPVKICDFDLGSGMEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPDLISKLLVRDAKQRLSAAQVLQHPWV 5wzx A 2.95 BS01 III C 1 V312 E313 K316 H326 Q329 I330 L333 L477 E480 V44 E45 K48 H58 Q61 I62 L65 L203 E206 29162643 ELTPDQQTLLHFIMDSYNKQRMPQEITNKLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV 5wzx A 2.95 BS02 7VX A 1 M303 M341 F342 S345 I365 S368 F379 M463 W467 F474 W482 M35 M73 F74 S77 I91 S94 F105 M189 W193 F200 W208 29162643 ELTPDQQTLLHFIMDSYNKQRMPQEITNKLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV 5wzx A 2.95 BS03 BU3 A 1 L353 P354 L361 L85 P86 L87 29162643 ELTPDQQTLLHFIMDSYNKQRMPQEITNKLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV 5wzx B 2.95 BS01 III D 1 V312 E313 K316 H326 Q329 I330 K334 L477 E480 V46 E47 K50 H60 Q63 I64 K68 L205 E208 29162643 ELTPDQQTLLHFIMDSYNKQRMPQEITNKNFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV 5wzx B 2.95 BS02 7VX B 1 L300 M341 F342 I365 S368 M378 H460 M463 W467 F474 W482 L34 M75 F76 I93 S96 M106 H188 M191 W195 F202 W210 29162643 ELTPDQQTLLHFIMDSYNKQRMPQEITNKNFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV 5x33 A 3.70 BS01 7Y9 A 1 L27 D66 V69 F76 L80 H96 C99 S102 M103 S106 W236 K267 I270 A271 A273 F274 S276 S277 L13 D52 V55 F62 L66 H82 C85 S88 M89 S92 W390 K419 I422 A423 A425 F426 S428 S429 3.2.1.17 SNTFIPLLAMILLSVSMVVGLPGNTFVVWSILKRMRKRSVTALMVLNLALADLAVLLTAPFFLHFLTWGTWSFGLAGCRLCHYICGVSMYASVLLITAMSLDRSLAVASPFLSQKVRTKTAARWLLVGIWGASFLLATPVLAFRKVVKLTNETDLCLAVYPSDRHKAFHLLFEAFTGFVVPFLIVVASYADISRRLRARGSGSNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYGSGSRFHRRRRTGRLVVIIILAFAAFWLPYHVVDLVEGSRVLAGDQSKQQLRNARKVCIALAFLSSSVNPLLYACA 5xag A 2.56 BS01 GTP A 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 5xag A 2.56 BS02 MG A 1 Q11 D69 E71 Q11 D69 E71 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 5xag A 2.56 BS03 CA A 1 D39 T41 G44 G45 F49 E55 D39 T41 G44 G45 F49 E55 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 5xag A 2.56 BS04 93X B 1 T179 A180 V181 T179 A180 V181 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 5xag B 2.56 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5xag B 2.56 BS02 MG B 1 Q11 N101 D179 Q11 N99 D177 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5xag B 2.56 BS03 CA B 1 E110 E113 E108 E111 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5xag B 2.56 BS04 93X B 1 G237 V238 C241 L242 L248 A250 D251 K254 L255 N258 M259 V315 A316 A317 I318 N350 K352 A354 G235 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 V309 A310 A311 I312 N344 K346 A348 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5xag C 2.56 BS01 GTP C 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5xag C 2.56 BS02 MG C 1 D69 E71 D69 E71 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5xag C 2.56 BS03 93X D 1 T179 A180 V181 T179 A180 V181 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5xag D 2.56 BS01 GDP D 1 G10 Q11 C12 Q15 A99 S140 G143 G144 T145 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 A97 S138 G141 G142 T143 D177 E181 N204 Y222 N226 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xag D 2.56 BS02 MG D 1 Q11 N101 D179 Q11 N99 D177 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xag D 2.56 BS03 93X D 1 G237 V238 C241 L242 L248 A250 D251 K254 L255 N258 M259 A316 A317 I318 K352 T353 A354 G235 V236 C239 L240 L246 A248 D249 K252 L253 N256 M257 A304 A305 I306 K340 T341 A342 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xag F 2.56 BS01 MG F 1 D200 R222 N242 D318 D153 R175 N192 D267 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSCTWFPESYVIYPTDEREVFLAAYNGNVWIAKSISSEASELLDFIHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKEYSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 5xag F 2.56 BS02 ACP F 1 I148 Q183 K184 Y185 L186 K198 H239 L240 T241 M320 I330 E331 N333 I117 Q136 K137 Y138 L139 K151 H189 L190 T191 M269 I279 E280 N282 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSCTWFPESYVIYPTDEREVFLAAYNGNVWIAKSISSEASELLDFIHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKEYSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 5xxr A 2.65 BS01 COA A 1 F19 M20 I71 V73 R78 H79 Q80 G81 G83 K84 L104 T105 S107 F108 R111 F19 M20 I71 V73 R78 H79 Q80 G81 G83 K84 L104 T105 S107 F108 R111 2.3.1.- 29241954 MLIRYKKSFEKIAMGLLSFMPNEKDLKQLQQTIKDYETDTDRQLFLWKEDEDIVGAIGVEKKDSEVEIRHISVNPSHRHQGIGKQMMDALKHLFKTQVLVPNELTQSFFERCQGQQDQDISYN 5xxr B 2.65 BS01 COA B 1 F19 M20 P21 I71 S72 V73 R78 H79 Q80 G81 G83 K84 L104 S107 F108 R111 F19 M20 P21 I71 S72 V73 R78 H79 Q80 G81 G83 K84 L104 S107 F108 R111 2.3.1.- 29241954 MLIRYKKSFEKIAMGLLSFMPNEKDLKQLQQTIKDYETDTDRQLFLWKEDEDIVGAIGVEKKDSEVEIRHISVNPSHRHQGIGKQMMDALKHLFKTQVLVPNELTQSFFERCQ 5xxs A 2.09 BS01 COA A 1 F19 M20 I71 S72 V73 R78 H79 Q80 G81 G83 K84 L104 T105 S107 F108 R111 F19 M20 I71 S72 V73 R78 H79 Q80 G81 G83 K84 L104 T105 S107 F108 R111 2.3.1.- 29241954 MLIRYKKSFEKIAMGLLSFMPNEKDLKQLQQTIKDYETDTDRQLFLWKEDEDIVGAIGVEKKDSEVEIRHISVNPSHRHQGIGKQMMDALKHLFKTQVLVPNELTQSFFERCQGQQD 5xxs B 2.09 BS01 COA B 1 F19 M20 P21 I71 S72 V73 R78 H79 Q80 G81 I82 G83 K84 L104 S107 F108 R111 F19 M20 P21 I71 S72 V73 R78 H79 Q80 G81 I82 G83 K84 L104 S107 F108 R111 2.3.1.- 29241954 MLIRYKKSFEKIAMGLLSFMPNEKDLKQLQQTIKDYETDTDRQLFLWKEDEDIVGAIGVEKKDSEVEIRHISVNPSHRHQGIGKQMMDALKHLFKTQVLVPNELTQSFFERCQGQQDQDISYN 5y9d A 2.50 BS01 FAD A 1 F146 M148 T149 H153 G154 S155 W186 G188 N247 V439 T442 W443 E444 D446 N448 V449 F145 M147 T148 H152 G153 S154 W185 G187 N246 V438 T441 W442 E443 D445 N447 V448 1.3.3.6 29198706 TTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSLWRAQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQNGQGTPREQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCARIHTRQHLISSFYARIATAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPRPPYYESTLKPFLFREEEDDEICDLD 5y9d A 2.50 BS02 FAD B 1 R317 Q319 F320 I331 Y334 R340 Q417 A418 G421 Y424 R316 Q318 F319 I330 Y333 R339 Q416 A417 G420 Y423 1.3.3.6 29198706 TTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSLWRAQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQNGQGTPREQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCARIHTRQHLISSFYARIATAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPRPPYYESTLKPFLFREEEDDEICDLD 5y9d B 2.50 BS01 FAD A 1 R317 Q319 F320 I331 Y334 R340 Q417 A418 G420 G421 Y424 R310 Q312 F313 I324 Y327 R333 Q410 A411 G413 G414 Y417 1.3.3.6 29198706 TTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSLWRAQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQNGQGTPREQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCARIHTRQHLISSFYARIATAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPRPPYYESTLKPFLFREEEDDEICDLDE 5y9d B 2.50 BS02 FAD B 1 F146 M148 T149 G154 S155 W186 I187 G188 N247 V439 T442 W443 D446 N448 V449 L452 F145 M147 T148 G153 S154 W185 I186 G187 N246 V432 T435 W436 D439 N441 V442 L445 1.3.3.6 29198706 TTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSLWRAQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKISQNGQGTPREQLLSPEFLVEAFRTASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCARIHTRQHLISSFYARIATAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQNPATNPRPPYYESTLKPFLFREEEDDEICDLDE 5yfb A 2.20 BS01 ZN A 1 H443 H448 E501 H437 H442 E495 3.4.14.4 29050944 HRERFLADKSAPLCGMDIRKSFDQLSSKEKLYTHYVTEASWAGARIIQAQWTPQATDLYDLLILTFSVNGKLADLNALKTSSGLSEDDWEALIQYTVQVLSNLVNYKTFGFTKIIPRVDAEKFESVVKASSNADQGSALFTKLKQHIYALSPESALFIGKRKDGHVSNYYLGEPVGDAEVDAIQNVAEKLGVDILNTRVKKNGAGDYTLLVASAKTSPPSVHDFQIDSTPAKLTIEYGDYASSLTKVVAALQEAKQYTANDHQSAMIEGYVKSFNSGSIPEHKAASTEWVKDIGPVVESYIGFVETYVDPYGGRAEWEGFTAIVDKQLSAKYEALVNGAPKLIKSLPWGTDFEVDVFRKPDFTALEVVSFATGGIPAGINIPNYYEVRESTGFKNVSLANILAAKVPNEELTFIHPDDVELYNAWDSRAFELQVANHELLGHGSGKLFQEGADGKLNFDPEKVINPLTGKPITSWYKPGQTPDSVLGEVSSSMEECRAETVALYLVSNLDILKIFNYVDKQDIEDIQYITFLLMARAGLRALEFYDPATKKHGQAHMQARMGITQYLIQAGIARLELIQDANGELENLYVRVDREKVLSKGKEVVGQLLIELQVRKSTADGTGSRDFYTTLTEPISGWEGKIRDIVLKKKLPRKIFVQPNTFVVNGEVQLKEYPLTAAGVIESFIERRLLE 5yfb B 2.20 BS01 ZN B 1 H443 H448 E501 H437 H442 E495 3.4.14.4 29050944 HRERFLADKSAPLCGMDIRKSFDQLSSKEKLYTHYVTEASWAGARIIQAQWTPQATDLYDLLILTFSVNGKLADLNALKTSSGLSEDDWEALIQYTVQVLSNLVNYKTFGFTKIIPRVDAEKFESVVKASSNADQGSALFTKLKQHIYALSPESALFIGKRKDGHVSNYYLGEPVGDAEVDAIQNVAEKLGVDILNTRVKKNGAGDYTLLVASAKTSPPSVHDFQIDSTPAKLTIEYGDYASSLTKVVAALQEAKQYTANDHQSAMIEGYVKSFNSGSIPEHKAASTEWVKDIGPVVESYIGFVETYVDPYGGRAEWEGFTAIVDKQLSAKYEALVNGAPKLIKSLPWGTDFEVDVFRKPDFTALEVVSFATGGIPAGINIPNYYEVRESTGFKNVSLANILAAKVPNEELTFIHPDDVELYNAWDSRAFELQVANHELLGHGSGKLFQEGADGKLNFDPEKVINPLTGKPITSWYKPGQTPDSVLGEVSSSMEECRAETVALYLVSNLDILKIFNYVDKQDIEDIQYITFLLMARAGLRALEFYDPATKKHGQAHMQARMGITQYLIQAGIARLELIQDANGELENLYVRVDREKVLSKGKEVVGQLLIELQVRKSTADGTGSRDFYTTLTEPISGWEGKIRDIVLKKKLPRKIFVQPNTFVVNGEVQLKEYPLTAAGVIESFIERRLL 5yfd A 1.76 BS01 CU A 1 H443 H448 E501 H437 H442 E495 3.4.14.4 29050944 HRERFLADKSAPLCGMDIRKSFDQLSSKEKLYTHYVTEASWAGARIIQAQWTPQATDLYDLLILTFSVNGKLADLNALKTSSGLSEDDWEALIQYTVQVLSNLVNYKTFGFTKIIPRVDAEKFESVVKASSNADQGSALFTKLKQHIYALSPESALFIGKRKDGHVSNYYLGEPVGDAEVDAIQNVAEKLGVDILNTRVKKNGAGDYTLLVASAKTSPPSVHDFQIDSTPAKLTIEYGDYASSLTKVVAALQEAKQYTANDHQSAMIEGYVKSFNSGSIPEHKAASTEWVKDIGPVVESYIGFVETYVDPYGGRAEWEGFTAIVDKQLSAKYEALVNGAPKLIKSLPWGTDFEVDVFRKPDFTALEVVSFATGGIPAGINIPNYYEVRESTGFKNVSLANILAAKVPNEELTFIHPDDVELYNAWDSRAFELQVANHELLGHGSGKLFQEGADGKLNFDPEKVINPLTGKPITSWYKPGQTPDSVLGEVSSSMEECRAETVALYLVSNLDILKIFNYVDKQDIEDIQYITFLLMARAGLRALEFYDPATKKHGQAHMQARMGITQYLIQAGIARLELIQDANGELENLYVRVDREKVLSKGKEVVGQLLIELQVRKSTADGTGSRDFYTTLTEPISGWEGKIRDIVLKKKLPRKIFVQPNTFVVNGEVQLKEYPLTAAGVIESFIERRL 5yfd B 1.76 BS01 CU B 1 H443 H448 E501 H437 H442 E495 3.4.14.4 29050944 HRERFLADKSAPLCGMDIRKSFDQLSSKEKLYTHYVTEASWAGARIIQAQWTPQATDLYDLLILTFSVNGKLADLNALKTSSGLSEDDWEALIQYTVQVLSNLVNYKTFGFTKIIPRVDAEKFESVVKASSNADQGSALFTKLKQHIYALSPESALFIGKRKDGHVSNYYLGEPVGDAEVDAIQNVAEKLGVDILNTRVKKNGAGDYTLLVASAKTSPPSVHDFQIDSTPAKLTIEYGDYASSLTKVVAALQEAKQYTANDHQSAMIEGYVKSFNSGSIPEHKAASTEWVKDIGPVVESYIGFVETYVDPYGGRAEWEGFTAIVDKQLSAKYEALVNGAPKLIKSLPWGTDFEVDVFRKPDFTALEVVSFATGGIPAGINIPNYYEVRESTGFKNVSLANILAAKVPNEELTFIHPDDVELYNAWDSRAFELQVANHELLGHGSGKLFQEGADGKLNFDPEKVINPLTGKPITSWYKPGQTPDSVLGEVSSSMEECRAETVALYLVSNLDILKIFNYVDKQDIEDIQYITFLLMARAGLRALEFYDPATKKHGQAHMQARMGITQYLIQAGIARLELIQDANGELENLYVRVDREKVLSKGKEVVGQLLIELQVRKSTADGTGSRDFYTTLTEPISGWEGKIRDIVLKKKLPRKIFVQPNTFVVNGEVQLKEYPLTAAGVIESFIERRL 5yud A 4.28 BS01 ATP A 1 L434 C436 T472 G473 G475 K476 T477 T478 P642 L269 C271 T307 G308 G310 K311 T312 T313 P477 29182158 DRISEIDYEFLPELSALLGVDAFQVAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVRLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKRPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQSYEGFVSEQLRDNYTKATFRHMNLPEVCSSLGTDHLLSCDVSIISKHISQPVQEALTIPEVFSNLNSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSSIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRDIRLYLGTSLEIQEFPFYNTVSVLRKFFSHDIICVEKLIIYFIDNKDLQGVYKTPLFVAAVCTDWIQNASAQDKFQDVTLFQSYMQYLSLKYKATAEPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEKLTTLLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQIDSPLKAINSFNIFLYYVSSHSSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPQTFLWFQFVRGLWLVSPESSSSFVSEHLLRLALIFAYESNTVAECSPFILQFLRGKTLALRVLNLQYFRDHPESLLLLRSLKVSINGNKMSSYVDYSFKTYFENLQPPAIDEEYTSAFEHISEWRRNFAQDEEIIKNYENIRPRALPDISEGYWKLSPKPCKIPKLEVQVNNTDAADQALLQVLMEVFSASQSIEFRLFNSSGFLESICPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPEQLFHNLHKFLGLKELCVRLDGKPNVLSVLPREFPNLLHMEKLSIQTSTESDLSKLVKFIQNFPNLHVFHLKCDFLSNCESLMAVLASCKKLREIEFSGRCFEAMTFVNILPNFVSLKILNLKDQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLTFHDILDDDSVIEIARAATSGGFQKLENLDISMNHKITEEGYRNFFQALDNLPNLQELNICRNIPGRIQVQATTVKALGQCVSRLPSLIRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKLIVPFSPVILE 5yw5 A 1.90 BS01 ADE A 1 M22 F23 R24 L125 L155 M25 F26 R27 L128 L158 2.4.2.7 DDKMNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF 5yw5 B 1.90 BS01 ADE B 1 M22 F23 R24 L125 M25 F26 R27 L121 2.4.2.7 DDKMNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF 5yw5 C 1.90 BS01 ADE C 1 M22 F23 R24 L125 M22 F23 R24 L125 2.4.2.7 MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF 5yw5 D 1.90 BS01 ADE D 1 M22 F23 R24 L125 M22 F23 R24 L125 2.4.2.7 MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF 5z02 A 1.35 BS01 NUT A 1 L33 G37 I40 M41 Q51 H52 F65 V72 H75 I78 Y79 L31 G35 I38 M39 Q49 H50 F63 V70 H73 I76 Y77 2.3.2.27 QETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVN 6b0o A 1.55 BS01 NUC B 1 R321 K332 Y334 K336 H339 K346 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 R424 E427 R430 R3 K14 Y16 K18 H21 K28 R44 F46 R48 Q51 R54 H55 R58 R72 F74 S75 R76 H79 H83 T86 R106 E109 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0o A 1.55 BS02 NUC C 1 S338 Y353 R366 S367 D368 K371 S395 D396 K399 R424 S425 D426 R430 S20 Y35 R48 S49 D50 K53 S77 D78 K81 R106 S107 D108 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0o A 1.55 BS03 ZN A 1 C355 C360 H373 H377 C37 C42 H55 H59 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0o A 1.55 BS04 ZN A 2 C385 C388 H401 H405 C67 C70 H83 H87 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0o A 1.55 BS05 ZN A 3 C413 C418 H431 H435 C95 C100 H113 H117 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0o A 1.55 BS06 ZN A 4 C325 C330 H343 H347 C7 C12 H25 H29 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0o D 1.55 BS01 NUC E 1 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 F422 R424 E427 R430 R42 F44 R46 Q49 R52 H53 R56 R70 F72 S73 R74 H77 H81 T84 F102 R104 E107 R110 RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0o D 1.55 BS02 NUC F 1 Y353 S367 S395 D396 K399 R424 S425 D426 R430 Y33 S47 S75 D76 K79 R104 S105 D106 R110 RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0o D 1.55 BS03 ZN D 1 C355 C360 H373 H377 C35 C40 H53 H57 RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0o D 1.55 BS04 ZN D 2 C385 C388 H401 H405 C65 C68 H81 H85 RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0o D 1.55 BS05 ZN D 3 C413 C418 H431 H435 C93 C98 H111 H115 RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0o D 1.55 BS06 ZN D 4 C325 C330 H343 H347 C5 C10 H23 H27 RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p D 2.08 BS01 NUC E 1 R321 F335 F364 R366 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 K420 R424 E427 R430 R3 F17 F46 R48 R54 H55 R58 R72 F74 S75 R76 H79 H83 T86 K102 R106 E109 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p D 2.08 BS02 NUC F 1 Y334 H339 Y353 R366 S367 D368 K371 R394 S395 D396 K399 R424 S425 D426 R430 Y16 H21 Y35 R48 S49 D50 K53 R76 S77 D78 K81 R106 S107 D108 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p D 2.08 BS03 ZN D 1 C325 C330 H343 H347 C7 C12 H25 H29 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p D 2.08 BS04 ZN D 2 C355 C360 H373 H377 C37 C42 H55 H59 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p D 2.08 BS05 ZN D 3 C385 C388 H401 H405 C67 C70 H83 H87 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p D 2.08 BS06 ZN D 4 C413 C418 H431 H435 C95 C100 H113 H117 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p A 2.08 BS01 NUC B 1 R321 F335 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 K420 R424 E427 R430 R3 F17 R44 F46 R48 Q51 R54 H55 R58 R72 F74 S75 R76 H79 H83 T86 K102 R106 E109 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p A 2.08 BS02 NUC C 1 Y334 H339 Y353 R366 S367 D368 K371 S395 D396 K399 R424 S425 D426 R430 Y16 H21 Y35 R48 S49 D50 K53 S77 D78 K81 R106 S107 D108 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p A 2.08 BS03 ZN A 1 C325 C330 H343 H347 C7 C12 H25 H29 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p A 2.08 BS04 ZN A 2 C355 C360 H373 H377 C37 C42 H55 H59 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p A 2.08 BS05 ZN A 3 C385 C388 H401 H405 C67 C70 H83 H87 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0p A 2.08 BS06 ZN A 4 C413 C418 H431 H435 C95 C100 H113 H117 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q D 2.79 BS01 NUC E 1 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 F422 R424 E427 R430 R44 F46 R48 Q51 R54 H55 R58 R72 F74 S75 R76 H79 H83 T86 F104 R106 E109 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q D 2.79 BS02 NUC F 1 S367 D368 K371 S395 D396 K399 R424 S425 D426 R430 S49 D50 K53 S77 D78 K81 R106 S107 D108 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q D 2.79 BS03 ZN D 1 C325 C330 H343 H347 C7 C12 H25 H29 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q D 2.79 BS04 ZN D 2 C355 C360 H373 H377 C37 C42 H55 H59 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q D 2.79 BS05 ZN D 3 C385 C388 H401 H405 C67 C70 H83 H87 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q D 2.79 BS06 ZN D 4 C413 C418 H431 H435 C95 C100 H113 H117 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0q A 2.79 BS01 NUC B 1 R345 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 F422 R424 E427 R430 R27 R44 F46 R48 Q51 R54 H55 R58 R72 F74 S75 R76 H79 H83 T86 F104 R106 E109 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0q A 2.79 BS02 NUC C 1 R366 D368 S395 D396 K399 R424 S425 D426 R430 R48 D50 S77 D78 K81 R106 S107 D108 R112 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0q A 2.79 BS03 ZN A 1 C325 C330 H343 H347 C7 C12 H25 H29 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0q A 2.79 BS04 ZN A 2 C355 C360 H373 H377 C37 C42 H55 H59 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0q A 2.79 BS05 ZN A 3 C385 C388 H401 H405 C67 C70 H83 H87 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0q A 2.79 BS06 ZN A 4 C413 C418 H431 H435 C95 C100 H113 H117 HMRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 6b0r D 1.82 BS01 NUC E 1 R321 Y334 F335 K336 H339 R342 K346 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 F422 R424 E427 R430 R2 Y15 F16 K17 H20 R23 K27 R43 F45 R47 Q50 R53 H54 R57 R71 F73 S74 R75 H78 H82 T85 F103 R105 E108 R111 MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r D 1.82 BS02 NUC F 1 L337 S338 Y353 S367 D368 K371 F383 R394 S395 D396 K399 S425 D426 L18 S19 Y34 S48 D49 K52 F64 R75 S76 D77 K80 S106 D107 MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r D 1.82 BS03 ZN D 1 C325 C330 H343 H347 C6 C11 H24 H28 MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r D 1.82 BS04 ZN D 2 C355 C360 H373 H377 C36 C41 H54 H58 MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r D 1.82 BS05 ZN D 3 C385 C388 H401 H405 C66 C69 H82 H86 MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r D 1.82 BS06 ZN D 4 C413 C418 H431 H435 C94 C99 H112 H116 MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r A 1.82 BS01 NUC B 1 R321 K332 Y334 F335 K336 H339 R342 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 K420 F422 R424 R430 R3 K14 Y16 F17 K18 H21 R24 F46 R48 Q51 R54 H55 R58 R72 F74 S75 R76 H79 H83 T86 K102 F104 R106 R112 HMRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r A 1.82 BS02 NUC C 1 L337 Y353 S367 D368 K371 R394 S395 D396 R424 S425 L19 Y35 S49 D50 K53 R76 S77 D78 R106 S107 HMRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r A 1.82 BS03 ZN A 1 C325 C330 H343 H347 C7 C12 H25 H29 HMRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r A 1.82 BS04 ZN A 2 C355 C360 H373 H377 C37 C42 H55 H59 HMRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r A 1.82 BS05 ZN A 3 C385 C388 H401 H405 C67 C70 H83 H87 HMRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b0r A 1.82 BS06 ZN A 4 C413 C418 H431 H435 C95 C100 H113 H117 HMRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 6b1c A 2.16 BS01 C9J A 1 P1 M2 K32 P33 Y36 H62 S63 I64 M101 V106 P1 M2 K32 P33 Y36 H62 S63 I64 M101 V106 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1c A 2.16 BS02 C9J B 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1c B 2.16 BS01 C9J B 1 P1 M2 K32 Y36 H62 S63 I64 M101 V106 F113 P1 M2 K32 Y36 H62 S63 I64 M101 V106 F113 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1c C 2.16 BS01 C9J A 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1k A 1.17 BS01 C9G A 1 P1 M2 K32 P33 Y36 H62 S63 I64 V106 F113 P1 M2 K32 P33 Y36 H62 S63 I64 V106 F113 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1k A 1.17 BS02 C9G B 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1k B 1.17 BS01 C9G B 1 P1 M2 K32 P33 Y36 H62 S63 I64 V106 F113 P1 M2 K32 P33 Y36 H62 S63 I64 V106 F113 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1k B 1.17 BS02 C9G C 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1k C 1.17 BS01 C9G A 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b1k C 1.17 BS02 C9G C 1 P1 M2 K32 P33 Y36 H62 S63 I64 V106 P1 M2 K32 P33 Y36 H62 S63 I64 V106 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b2c A 2.00 BS01 C9Y B 1 Y95 N97 Y95 N97 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b2c B 2.00 BS01 C9Y B 1 P1 M2 K32 Y36 H62 S63 I64 M101 V106 F113 P1 M2 K32 Y36 H62 S63 I64 M101 V106 F113 5.3.2.1,5.3.3.12 29259749 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 6b30 A 2.69 BS01 CFG A 1 Q286 L287 C320 H323 M365 A368 F377 F378 E379 F388 Q22 L23 C56 H59 M101 A104 F113 F114 E115 F124 29262987 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQH 6b30 B 2.69 BS01 CFG B 1 Q286 L287 C320 H323 R364 M365 A368 F377 F378 E379 F388 Q22 L23 C56 H59 R100 M101 A104 F113 F114 E115 F124 29262987 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLC 6b36 A 1.63 BS01 CKD B 1 R8 D25 G27 G48 G49 I50 P81 V82 I84 R8 D25 G27 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b36 B 1.63 BS01 CKD B 1 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b38 A 1.48 BS01 CKM B 1 R8 L23 D25 G27 A28 G48 G49 I50 P81 V82 I84 R8 L23 D25 G27 A28 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b38 A 1.48 BS02 CKM B 2 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b38 B 1.48 BS01 CKM B 1 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b38 B 1.48 BS02 CKM B 3 R8 L23 D25 G27 G48 G49 I50 P81 V82 I84 R8 L23 D25 G27 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3c A 1.60 BS01 CKS B 1 R8 D25 G27 A28 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3c B 1.60 BS01 CKS B 1 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3f A 1.46 BS01 CKV B 1 R8 L23 D25 G27 G48 G49 I50 P81 V82 I84 R8 L23 D25 G27 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3f B 1.46 BS01 CKV B 1 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 L23 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3g A 1.50 BS01 CKY B 1 R8 L23 D25 G27 G48 G49 I50 P81 V82 I84 R8 L23 D25 G27 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3g A 1.50 BS02 CKY B 2 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3g B 1.50 BS01 CKY B 1 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3g B 1.50 BS02 CKY B 3 R8 D25 G27 A28 G48 G49 I50 P81 V82 I84 R8 D25 G27 A28 G48 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3h A 1.62 BS01 CN4 A 1 G27 D29 D30 V32 K45 I47 G48 L76 G27 D29 D30 V32 K45 I47 G48 L76 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3h A 1.62 BS02 CN4 B 1 R8 L23 D25 G27 G49 I50 P81 V82 I84 R8 L23 D25 G27 G49 I50 P81 V82 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3h B 1.62 BS01 CN4 A 1 R8 L23 P81 V82 R8 L23 P81 V82 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6b3h B 1.62 BS02 CN4 B 1 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 I84 D25 G27 A28 D29 D30 V32 I47 G48 G49 I50 I84 3.4.23.16 29259750 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 6blw A 1.84 BS01 NUC B 1 R321 K332 Y334 F335 K336 H339 R342 K346 R362 F364 R366 R372 H373 R376 R390 F392 R394 H397 H401 T404 R5 K16 Y18 F19 K20 H23 R26 K30 R46 F48 R50 R56 H57 R60 R74 F76 R78 H81 H85 T88 HMEKRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKSCRWPSCQLVRHHNMHQ 6blw A 1.84 BS02 NUC C 1 S338 Q341 D368 K371 F383 R394 S395 D396 S420 S22 Q25 D52 K55 F67 R78 S79 D80 S98 HMEKRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKSCRWPSCQLVRHHNMHQ 6blw A 1.84 BS03 ZN A 1 C355 C360 H373 H377 C39 C44 H57 H61 HMEKRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKSCRWPSCQLVRHHNMHQ 6blw A 1.84 BS04 ZN A 2 C385 C388 H401 H405 C69 C72 H85 H89 HMEKRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKSCRWPSCQLVRHHNMHQ 6blw A 1.84 BS05 ZN A 3 C325 C330 H343 H347 C9 C14 H27 H31 HMEKRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKSCRWPSCQLVRHHNMHQ 6blw A 1.84 BS06 ZN A 4 C416 C421 H434 H438 C94 C99 H104 H108 HMEKRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKSCRWPSCQLVRHHNMHQ 6bm7 A 2.98 BS01 DY7 B 1 F28 E85 F20 E77 4.1.1.50 29271204 KDSLSLMAMWGSIARFDPSFEGPEKRLEVIMRVVDGTHVSGLLAHDDDVWQKVIDAICAHIVSREFNEYIRSYVLSE 6bm7 B 2.98 BS01 DY7 B 1 C100 Y243 C246 Y248 S249 H262 I263 T264 P265 E266 C14 Y157 C160 Y162 S163 H176 I177 T178 P179 E180 4.1.1.50 29271204 SLFVMKDRVILITCGTITLLNCVPLICEAVSTVCGEVEWVSFMHKNYSFPWEQKGPHLSMAEEFKTLRSHFPSGQPFIFGPIDSDHYFLYFHSDVVQPSCSDDAQLSMTMYGLDRNQTKHWYSDKMLPTGPETAVIREATGLSEVVDDSWILHDLQYEPCGYSINAIRGSEYQTIHITPEEHCSFASYETNTCALNYSKCICGVLRVFDPERFSVIVFIDPDSAVGKSYHSGGTIGVEPEYYPNYEAHHRTVNEYTPGHWVLKVNYVKRA 6bm7 C 2.98 BS01 DY7 D 1 F28 E85 F22 E79 4.1.1.50 29271204 KDSLSLMAMWGSIARFDPKRSFEGPEKRLEVIMRVVDGTHVSGLLAHDDDVWQKVIDAICAHIVSREFNEYIRSYVLSE 6bm7 D 2.98 BS01 DY7 D 1 C100 C246 S249 H262 T264 P265 E266 C14 C160 S163 H176 T178 P179 E180 4.1.1.50 29271204 SLFVMKDRVILITCGTITLLNCVPLICEAVSTVCGEVEWVSFMHKNYSFPWEQKGPHLSMAEEFKTLRSHFPSGQPFIFGPIDSDHYFLYFHSDVVQPSCSDDAQLSMTMYGLDRNQTKHWYSDKMLPTGPETAVIREATGLSEVVDDSWILHDLQYEPCGYSINAIRGSEYQTIHITPEEHCSFASYETNTCALNYSKCICGVLRVFDPERFSVIVFIDPDSAVGKSYHSGGTIGVEPEYYPNYEAHHRTVNEYTPGHWVLKVNYVKRA 6bmt A 2.40 BS01 CA A 1 D262 T334 S335 F336 D338 S340 D97 T163 S164 F165 D167 S169 1.11.2.2 TCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAAGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA 6bmt A 2.40 BS02 HEM A 1 M253 G256 Q257 D260 D264 F265 T266 R405 E408 M409 T495 F498 R499 H502 I505 F531 F573 R590 M88 G91 Q92 D95 D99 F100 T101 R234 E237 M238 T324 F327 R328 H331 I334 F360 F402 R419 1.11.2.2 TCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAAGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA 6bmt B 2.40 BS01 HEM A 1 Q32 N33 Q5 N6 QVTSQNGIILHDDSRMLDHELQYVDVLINPNANPQTKERLKAYFESQGLNTVSEIVQKAKQDGLDTSKYD 6bsg A 2.44 BS01 NUC D 1 Y183 M230 G231 N255 Q258 K259 G262 K263 W266 A360 H361 K366 Q407 R448 T473 N474 Q475 Y501 Y171 M218 G219 N243 Q246 K247 G250 K251 W254 A348 H349 K354 Q395 R436 T461 N462 Q463 Y489 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsg A 2.44 BS02 NUC R 1 V21 K22 Q23 W24 P59 A62 R78 L92 N265 C280 L283 R284 G285 M357 R448 N474 Q475 E478 D498 S499 Q500 W535 P537 A538 H539 R557 V18 K19 Q20 W21 P56 A59 R66 L80 N253 C268 L271 R272 G273 M345 R436 N462 Q463 E466 D486 S487 Q488 W523 P525 A526 H527 R545 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsg A 2.44 BS03 EFZ A 1 L100 K101 K103 V106 Y181 Y188 G190 F227 W229 L234 H235 Y318 L88 K89 K91 V94 Y169 Y176 G178 F215 W217 L222 H223 Y306 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsg A 2.44 BS04 CA A 1 D443 E478 D498 D431 E466 D486 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsg A 2.44 BS05 CA A 2 D443 G444 D549 R557 D431 G432 D537 R545 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsg B 2.44 BS01 NUC D 1 Q394 K395 F416 N418 Q365 K366 F387 N389 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEP 6bsg B 2.44 BS02 NUC R 1 W266 N418 P420 W242 N389 P391 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEP 6bsh A 2.65 BS01 NUC D 1 K73 Q151 G152 M230 G231 Q242 N255 Q258 K259 G262 K263 W266 A360 H361 K366 Q407 R448 T473 N474 Q475 Y501 K60 Q138 G139 M217 G218 Q229 N242 Q245 K246 G249 K250 W253 A347 H348 K353 Q394 R435 T460 N461 Q462 Y488 2.7.7.7 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsh A 2.65 BS02 NUC R 1 V21 K22 Q23 W24 P59 K73 R78 L92 N265 C280 L283 R284 G285 R358 D443 G444 A445 A446 N474 Q475 E478 D498 Q500 W535 P537 A538 H539 I556 R557 V18 K19 Q20 W21 P56 K60 R65 L79 N252 C267 L270 R271 G272 R345 D430 G431 A432 A433 N461 Q462 E465 D485 Q487 W522 P524 A525 H526 I543 R544 2.7.7.7 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsh A 2.65 BS03 EFZ A 1 L100 K101 K103 V106 V179 Y181 Y188 G190 F227 W229 L234 H235 Y318 L87 K88 K90 V93 V166 Y168 Y175 G177 F214 W216 L221 H222 Y305 2.7.7.7 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsh A 2.65 BS04 CA A 1 D443 D549 D430 D536 2.7.7.7 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsh A 2.65 BS05 CA A 2 D443 E478 D498 D430 E465 D485 2.7.7.7 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsh B 2.65 BS01 NUC D 1 Q394 K395 F416 N418 Q365 K366 F387 N389 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEP 6bsh B 2.65 BS02 NUC R 1 W266 N418 P420 W242 N389 P391 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEP 6bsi A 3.25 BS01 NUC D 1 Q151 M184 M230 G231 N255 Q258 K259 G262 K263 W266 R358 G359 A360 H361 Q407 T473 Q475 Y501 I505 Q137 M170 M216 G217 N241 Q244 K245 G248 K249 W252 R344 G345 A346 H347 Q393 T459 Q461 Y487 I491 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsi A 3.25 BS02 NUC R 1 V21 K22 W24 P59 R78 L92 N265 C280 R284 T286 A355 N474 H539 V18 K19 W21 P56 R64 L78 N251 C266 R270 T272 A341 N460 H525 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsi A 3.25 BS03 EFZ A 1 L100 K101 K103 V106 V179 Y181 Y188 G190 F227 W229 L234 H235 Y318 L86 K87 K89 V92 V165 Y167 Y174 G176 F213 W215 L220 H221 Y304 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsi A 3.25 BS04 CA A 1 D443 G444 E478 D498 D429 G430 E464 D484 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsi B 3.25 BS01 NUC D 1 Q394 K395 F416 N418 Q366 K367 F388 N390 ETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPI 6bsi B 3.25 BS02 NUC R 1 E415 P420 E387 P392 ETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPI 6bsj A 2.89 BS01 NUC D 1 Q151 M184 M230 G231 Q242 N255 Q258 K259 G262 K263 W266 A360 R448 Q137 M170 M216 G217 Q228 N241 Q244 K245 G248 K249 W252 A346 R434 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsj A 2.89 BS02 NUC R 1 V21 K22 W24 P59 R78 L92 N265 C280 L283 R284 G285 M357 N474 Q500 R557 V18 K19 W21 P56 R64 L78 N251 C266 L269 R270 G271 M343 N460 Q486 R543 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsj A 2.89 BS03 EFZ A 1 L100 K101 K103 V106 Y181 Y188 G190 F227 W229 L234 H235 Y318 L86 K87 K89 V92 Y167 Y174 G176 F213 W215 L220 H221 Y304 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsj A 2.89 BS04 CA A 1 D443 G444 E478 D498 D429 G430 E464 D484 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 6bsj B 2.89 BS01 NUC D 1 K395 F416 N418 K362 F383 N385 TVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWVPEWEFVNTPPLVKLWYQLEKEP 6bsn A 2.15 BS01 FDA A 1 D278 A279 A310 Q312 Y314 R339 V341 K342 G343 A344 Y345 W346 F364 T365 R366 K367 T370 A393 T394 H395 N396 Q416 R417 Y441 S466 F467 D269 A270 A301 Q303 Y305 R330 V332 K333 G334 A335 Y336 W337 F355 T356 R357 K358 T361 A384 T385 H386 N387 Q407 R408 Y432 S457 F458 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS02 PRO A 1 F659 R791 S793 I945 G946 A947 F954 F644 R776 S778 I930 G931 A932 F939 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS03 PRO A 2 M645 A973 R974 A976 E978 M630 A958 R959 A961 E963 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS04 PRO A 3 R244 R284 R235 R275 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS05 PRO A 4 W657 N658 G733 F886 W642 N643 G718 F871 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn A 2.15 BS06 PRO B 1 P964 H970 P949 H955 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS01 PRO A 5 P964 H970 P949 H955 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS02 FDA B 1 D278 A279 A310 Q312 Y314 R339 V341 K342 G343 A344 Y345 W346 F364 T365 R366 K367 T370 A393 T394 H395 N396 Q416 R417 L418 Y441 E460 S466 F467 D269 A270 A301 Q303 Y305 R330 V332 K333 G334 A335 Y336 W337 F355 T356 R357 K358 T361 A384 T385 H386 N387 Q407 R408 L409 Y432 E451 S457 F458 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS03 PRO B 2 F659 R791 S793 I945 G946 A947 F954 F644 R776 S778 I930 G931 A932 F939 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS04 PRO B 1 M645 R648 A973 R974 A976 E978 M630 R633 A958 R959 A961 E963 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS05 PRO B 3 R244 E246 R284 R235 E237 R275 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bsn B 2.15 BS06 PRO B 4 W657 N658 G733 F886 W642 N643 G718 F871 IPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWALRVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPRSGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADDVVTSAFRSAGQRASALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 6bwp A 1.70 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 6bwp B 1.70 BS01 HEM B 1 L31 F41 F42 H63 K66 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 L141 L31 F41 F42 H63 K66 V67 A70 L88 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 6bwp B 1.70 BS02 EBJ B 1 C93 D94 K144 H146 C93 D94 K144 H146 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 6bwp C 1.70 BS01 HEM C 1 Y42 F43 H45 F46 H58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 6bwp D 1.70 BS01 HEM D 1 L31 F41 F42 H63 K66 V67 A70 L91 H92 L96 V98 N102 F103 L106 L141 L31 F41 F42 H63 K66 V67 A70 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 6bwp D 1.70 BS02 EBJ D 1 C93 D94 K144 H146 C93 D94 K144 H146 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 6bwu A 2.00 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 A65 L66 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 A65 L66 L83 L86 H87 L91 V93 N97 F98 L101 L136 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 6bwu B 2.00 BS01 HEM B 1 T38 F41 F42 H63 K66 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 T38 F41 F42 H63 K66 V67 A70 F71 L88 L91 H92 L96 V98 N102 F103 L106 L141 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAH 6bwu B 2.00 BS02 EBJ B 1 C93 V98 P100 F103 A142 C93 V98 P100 F103 A142 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAH 6bz0 A 1.83 BS01 FAD A 1 I10 G11 G13 P14 G15 I33 E34 K35 R36 G46 T47 C48 G52 C53 K57 G119 T120 G121 A149 S150 G151 S152 S170 I191 R278 Y281 G317 D318 M324 L325 A326 A329 Y357 I7 G8 G10 P11 G12 I30 E31 K32 R33 G43 T44 C45 G49 C50 K54 G116 T117 G118 A146 S147 G148 S149 S167 I188 R275 Y278 G314 D315 M321 L322 A323 A326 Y354 1.8.1.4 QFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSHRYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVNDHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHGHAAQVNYDTIISIIYTHPEAAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAGFVKFVADAKTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIHAI 6bz0 B 1.83 BS01 FAD B 1 I10 G11 G13 P14 G15 I33 E34 K35 R36 G46 T47 C48 G52 C53 K57 G119 T120 G121 A149 S150 G151 S152 S170 I191 R278 Y281 G317 D318 M324 L325 A326 H327 A329 Y357 I7 G8 G10 P11 G12 I30 E31 K32 R33 G43 T44 C45 G49 C50 K54 G116 T117 G118 A146 S147 G148 S149 S167 I188 R275 Y278 G314 D315 M321 L322 A323 H324 A326 Y354 1.8.1.4 QFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSHRYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVNDHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHGHAAQVNYDTIISIIYTHPEAAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAGFVKFVADAKTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIHAI 6bz0 C 1.83 BS01 FAD C 1 I10 G11 G13 P14 G15 I33 E34 K35 R36 G46 T47 C48 G52 C53 K57 G119 T120 G121 A149 S150 G151 S170 I191 R278 Y281 G317 D318 M324 L325 A326 Y357 I6 G7 G9 P10 G11 I29 E30 K31 R32 G42 T43 C44 G48 C49 K53 G115 T116 G117 A145 S146 G147 S166 I187 R274 Y277 G313 D314 M320 L321 A322 Y353 1.8.1.4 FDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSHRYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVNDHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHGHAAQVNYDTIISIIYTHPEAAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAGFVKFVADAKTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIHAI 6bz0 D 1.83 BS01 FAD D 1 I10 G11 G13 P14 G15 I33 E34 K35 R36 G46 T47 C48 G52 C53 K57 G119 T120 G121 A149 S150 G151 S152 S170 I191 R278 Y281 G317 D318 M324 L325 A326 H327 A329 Y357 I8 G9 G11 P12 G13 I31 E32 K33 R34 G44 T45 C46 G50 C51 K55 G117 T118 G119 A147 S148 G149 S150 S168 I189 R276 Y279 G315 D316 M322 L323 A324 H325 A327 Y355 1.8.1.4 QQFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSHRYEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVNDHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHGHAAQVNYDTIISIIYTHPEAAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAGFVKFVADAKTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIHA 6elq X 2.52 BS01 SF4 X 1 C47 R48 H49 C50 G53 C55 G67 I68 C69 R79 M198 C44 R45 H46 C47 G50 C52 G64 I65 C66 R76 M195 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq X 2.52 BS02 BF8 X 1 H261 C294 C295 F312 C333 G445 C446 C476 C525 Q559 H560 K562 H258 C291 C292 F309 C330 G442 C443 C473 C522 Q556 H557 K559 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq X 2.52 BS03 SF4 A 1 C38 G41 C46 R48 C35 G38 C43 R45 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq A 2.52 BS01 SF4 A 1 C38 F40 G41 C46 R48 R56 C35 F37 G38 C43 R45 R53 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq A 2.52 BS02 SF4 A 2 C47 C50 G53 C55 G67 I68 C69 R79 M198 C44 C47 G50 C52 G64 I65 C66 R76 M195 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq A 2.52 BS03 BF8 A 1 H261 C294 C295 F312 C333 G445 C446 C476 C525 Q559 H560 K562 H258 C291 C292 F309 C330 G442 C443 C473 C522 Q556 H557 K559 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq B 2.52 BS01 SF4 B 1 C47 R48 C50 Q52 C55 G67 C69 I76 R79 M198 C44 R45 C47 Q49 C52 G64 C66 I73 R76 M195 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq B 2.52 BS02 SF4 B 2 C38 F40 G41 C46 P54 C35 F37 G38 C43 P51 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6elq B 2.52 BS03 BF8 B 1 H261 C294 C295 F312 C333 G445 C446 C476 C525 Q559 H560 K562 H258 C291 C292 F309 C330 G442 C443 C473 C522 Q556 H557 K559 1.2.7.4 29024326 SKLSVDPVIPNLYRKAREEGISTVFDRYEAQQPQCGFGLTGLCCRHCVQGPCRIDPFGEGPQAGICGATAEVITARNLLRQVTAGAAAHVDHAYDVLEVLEQIAQGTESYSIKDQEKLKQVAFTLGIDTANKTEQEIVEEMCQIIYRDFANSGATPMTYLKANSPRERLETWEKLGVLPRNPDREIREALHQTTMGMDADPVNLILKTIRLGLVDGFAGLKLATDLQDIIFGTPQPVVTEANLGVLKEDYVNIIVHGHVPLLSEKIVEWSRKLEDEAKKAGAKGINLAGICCTGNEVLMRQGVPLATNFLAQELAIITGAVDLMVVDVQCIMPSLAEIAACYHTRLVTTMPIVKIPGAEHVPFTTETADEASQQIVRMAIESYQKRNPAKVYIPREKAKVVAGFSVEAIVKALAKLNPDDPLKPLIDNIVSGNILGVVATVGCNNVKVKHDWFHIELVKELIKNNVLVVTTGCSAHALAKAGLMDPAAAEWAGEGLRAVLTAIGTANDLGGPLPPVLHMGSCVDNSRIGDLVIAVANYLKVSPKDLPIAASAPEYQHEKALSIGTWAVAMGIMTHLGVVPPVVGSSKVTRILTQDAEALIGGKFYVETDPYKAAAGIIEHIKAKRALLNL 6enz A 3.00 BS01 PLP A 1 L102 G160 G161 S162 H200 T257 D282 S284 W285 N311 K314 L92 G150 G151 S152 H190 T247 D272 S274 W275 N301 K304 VDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLMEPEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM 6enz A 3.00 BS02 PLP B 1 C365 S366 C350 S351 VDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKATDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLMEPEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM 6enz B 3.00 BS01 PLP A 1 C365 S366 C349 S350 VDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKADKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLMEPEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM 6enz B 3.00 BS02 PLP B 1 L102 G160 G161 S162 H200 T253 G255 T257 D282 S284 W285 N311 H313 K314 L92 G150 G151 S152 H190 T243 G245 T247 D272 S274 W275 N301 H303 K304 VDGVVLNGPQTDVKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWQPPEQLRQLLDLEMRDTGESQDKLLKLCQDVIHFSVKTNHPRFFNQLYAGLDYYSLAARIITEALNPSIYTYEVSPVFLLVEEAVLKKMIECVGWKEGDGIFNPGGSVSNMCAMNLARYRHCPDIKEKGLSGLPRLILFTSAECHYSMKKAASFLGIGTQNVYFVETDGRGKMIPEDLEKQIWQARQEGAVPFLVCATSGTTVLGAFDPLDEIAEVCERHGLWLHVDASWGGSALVSRKHRRLLHGIHRADSVAWNPHKMLMAGIQCSALLVKDKSDLLKKCYSAKADKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTSGLEERVNRAFALSRYLVDEIKKREGFKLLMEPEYTNVCFWYIPPSLREMEEGPEFWRKLSLVAPAIKEKMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDSLGRDM 6es9 A 1.37 BS01 COA A 1 Q74 R81 F473 W476 Q68 R75 F467 W470 1.3.8.- 29275330 MPADTPSALLALAGEALPELESLQSRATEALRALVAPAGKPQPALLEQHQHAAHALSWLTTYVESIRQLSGWAGRLAEAGNLGRIEALILQIGLGEYLGQIAGGIPMSQTEFARLSDLELDWQPGEAAAKLMRGNTAPARAELARLMQDNHGRATFGATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLLD 6es9 A 1.37 BS02 FAD A 1 Q56 A285 F287 T288 G293 S294 W318 I319 T320 R376 E380 I533 F534 A537 E539 I540 Q50 A279 F281 T282 G287 S288 W312 I313 T314 R370 E374 I527 F528 A531 E533 I534 1.3.8.- 29275330 MPADTPSALLALAGEALPELESLQSRATEALRALVAPAGKPQPALLEQHQHAAHALSWLTTYVESIRQLSGWAGRLAEAGNLGRIEALILQIGLGEYLGQIAGGIPMSQTEFARLSDLELDWQPGEAAAKLMRGNTAPARAELARLMQDNHGRATFGATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLLD 6es9 A 1.37 BS03 FAD B 1 R440 Q442 F443 L447 F450 Q508 I509 G511 G512 F515 R434 Q436 F437 L441 F444 Q502 I503 G505 G506 F509 1.3.8.- 29275330 MPADTPSALLALAGEALPELESLQSRATEALRALVAPAGKPQPALLEQHQHAAHALSWLTTYVESIRQLSGWAGRLAEAGNLGRIEALILQIGLGEYLGQIAGGIPMSQTEFARLSDLELDWQPGEAAAKLMRGNTAPARAELARLMQDNHGRATFGATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLLD 6es9 B 1.37 BS01 FAD A 1 R440 Q442 F443 L447 F450 Q508 I509 G511 G512 F515 R434 Q436 F437 L441 F444 Q502 I503 G505 G506 F509 1.3.8.- 29275330 MPADTPSALLALAGEALPELESLQSRATEALRALVAPAGKPQPALLEQHQHAAHALSWLTTYVESIRQLSGWAGRLAEAGNLGRIEALILQIGLGEYLGQIAGGIPMSQTEFARLSDLELDWQPGEAAAKLMRGNTAPARAELARLMQDNHGRATFGATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLLD 6es9 B 1.37 BS02 COA B 1 Q74 R81 F473 W476 Q68 R75 F467 W470 1.3.8.- 29275330 MPADTPSALLALAGEALPELESLQSRATEALRALVAPAGKPQPALLEQHQHAAHALSWLTTYVESIRQLSGWAGRLAEAGNLGRIEALILQIGLGEYLGQIAGGIPMSQTEFARLSDLELDWQPGEAAAKLMRGNTAPARAELARLMQDNHGRATFGATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLLD 6es9 B 1.37 BS03 FAD B 1 Q56 A285 F287 T288 G293 S294 W318 I319 T320 R376 E380 I533 F534 A537 E539 I540 Q50 A279 F281 T282 G287 S288 W312 I313 T314 R370 E374 I527 F528 A531 E533 I534 1.3.8.- 29275330 MPADTPSALLALAGEALPELESLQSRATEALRALVAPAGKPQPALLEQHQHAAHALSWLTTYVESIRQLSGWAGRLAEAGNLGRIEALILQIGLGEYLGQIAGGIPMSQTEFARLSDLELDWQPGEAAAKLMRGNTAPARAELARLMQDNHGRATFGATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIEVLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEIQAQVIARRLLD 6ess A 1.91 BS01 4IR A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 L110 A112 T114 P118 A121 D128 N11 L13 S15 Y31 S33 V35 G36 N37 W67 A74 S76 T78 W80 W96 L98 A100 T102 P106 A109 D116 29265726 DEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTAGTTEAPAWAMTLVGHDTFTKVK 6esu A 1.78 BS01 6IR A 1 N23 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 L110 R112 Y124 D128 N11 S15 Y31 S33 V35 G36 N37 W67 A74 S76 T78 W80 W96 L98 R100 Y112 D116 29265726 DEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTRGTTEAPAWAMTYVGHDTFTKVKP 6f5u A 2.07 BS01 CQN A 1 R64 V66 A101 R33 V35 A70 29272110 SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQASGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWELSFTVVGGGGGGG 6f5u B 2.07 BS01 CQN A 1 L515 Y517 M548 L558 L14 Y16 M47 L57 29272110 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFVD 6f6i A 2.40 BS01 8PR A 1 R64 V66 G67 L68 E100 A101 G102 R34 V36 G37 L38 E70 A71 G72 29272110 RSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQASGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTWAFWETLSFTVVGGGGGGG 6f6i B 2.40 BS01 8PR A 1 L515 Y517 M548 L14 Y16 M47 29272110 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFVD 6f6n A 2.15 BS01 SRE A 1 I38 R64 V66 A101 L186 I7 R33 V35 A70 L155 29272110 SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWETSEELSFTVVGGGGGGG 6f6n B 2.15 BS01 SRE A 1 Y517 M548 L558 Y16 M47 L57 29272110 EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFVD 6f6s A 2.29 BS01 CXQ A 1 R64 A101 R34 A71 29272110 RSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTWAFWETELSFTVVGGGGGG 6f6s A 2.29 BS02 CXQ B 1 V66 L184 L186 V36 L154 L156 29272110 RSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTWAFWETELSFTVVGGGGGG 6f6s B 2.29 BS01 CXQ A 1 Y517 Q521 I544 Y16 Q20 I41 29272110 EAIVNAQPKCNPNLHYWTTQDAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFVD 6f6s B 2.29 BS02 CXQ B 1 Y517 M548 L554 Y16 M45 L51 29272110 EAIVNAQPKCNPNLHYWTTQDAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPADWTKNITDKIDQIIHDFVD 6fd3 A 1.52 BS01 MG A 1 N407 D420 N148 D161 2.7.11.1 SMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLDKPLSSLTPLIIAAKEAIKN 6fd3 A 1.52 BS02 ADP A 1 I289 G290 G292 A293 S294 G295 V297 A310 K312 M357 E358 Y359 L360 D406 N407 L409 D420 I30 G31 G33 A34 S35 G36 V38 A51 K53 M98 E99 Y100 L101 D147 N148 L150 D161 2.7.11.1 SMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLDKPLSSLTPLIIAAKEAIKN