5h29 A 2.30 BS01 PRO A 1 K369 Q467 P468 K16 Q114 P115 Q830N9 28935609 WFPESMRQQLSGIFAKLTKKVTLLQFLDASDEKSLELQSFLTEFASLDQKITLETILKDTEPAKELLYGIEKMPSVVLLDAAGNYTGIKFSGIPSGHEVNSLVLAVYNVGSEGQPLEASLQKNILALPKRKIEIFVSLTCHFCPDVVAACQRIASINPHVEAEMVDISLFPELKKEKKIMSVPAMLIDGEQMIFGSKTMTEIIEALA 5h74 C 2.60 BS01 7LG B 1 L248 V250 P325 N329 F351 V353 I355 L248 V250 P325 N329 F351 V353 I355 Q2XVP4 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5h74 D 2.60 BS01 GTP D 1 G10 Q11 C12 Q15 E69 A97 G98 N99 S138 G141 G142 T143 G144 V175 S176 E181 N204 Y222 N226 G10 Q11 C12 Q15 E69 A97 G98 N99 S138 G141 G142 T143 G144 V175 S176 E181 N204 Y222 N226 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5h74 D 2.60 BS03 7LG D 1 Q11 Q15 P173 K174 V175 D177 P220 T221 Y222 G223 L225 R276 Q11 Q15 P173 K174 V175 D177 P220 T221 Y222 G223 L225 R276 Q6B856 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5h74 F 2.60 BS01 ACP F 1 K74 I148 Q183 K184 Y185 L186 K198 D200 L240 T241 N242 I330 E331 N333 K74 I126 Q150 K151 Y152 L153 K165 D167 L207 T208 N209 I293 E294 N296 E1BQ43 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIALISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 5h7w A 1.90 BS01 ZN A 1 D37 H39 D85 D12 H14 D60 GSFELTILHTNDVHARLEQTSRDSGKCTGEDCYGGVARRATKIRQIRASHRNVLLLDAGDQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDNGLNGLLDPLLKNVKFPILSANIRPKGPIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHADKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPPSNEVAAGNYPFMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILLNKSIQEDPAVKAEISRMKVQLQNYSSQEIGRTIVYLNGTTHACRFHECNLGNLICDAVVYNNLRHPDDNEWNHVSMCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHRHGQGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLAAGGDGYYMLKGDSSNHSSGDLDISIVGDYIKRMGKVFPAMEGRMVFSAGS 5h7w A 1.90 BS02 ZN A 2 D85 N117 H220 H243 D60 N92 H195 H218 GSFELTILHTNDVHARLEQTSRDSGKCTGEDCYGGVARRATKIRQIRASHRNVLLLDAGDQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDNGLNGLLDPLLKNVKFPILSANIRPKGPIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHADKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPPSNEVAAGNYPFMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILLNKSIQEDPAVKAEISRMKVQLQNYSSQEIGRTIVYLNGTTHACRFHECNLGNLICDAVVYNNLRHPDDNEWNHVSMCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHRHGQGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLAAGGDGYYMLKGDSSNHSSGDLDISIVGDYIKRMGKVFPAMEGRMVFSAGS 5h7w A 1.90 BS03 CA A 1 N213 D237 G298 N188 D212 G273 GSFELTILHTNDVHARLEQTSRDSGKCTGEDCYGGVARRATKIRQIRASHRNVLLLDAGDQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDNGLNGLLDPLLKNVKFPILSANIRPKGPIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHADKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPPSNEVAAGNYPFMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILLNKSIQEDPAVKAEISRMKVQLQNYSSQEIGRTIVYLNGTTHACRFHECNLGNLICDAVVYNNLRHPDDNEWNHVSMCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHRHGQGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLAAGGDGYYMLKGDSSNHSSGDLDISIVGDYIKRMGKVFPAMEGRMVFSAGS 5mqj A 3.70 BS02 UMP A 1 I30 A31 K34 E53 W58 L82 M85 Y86 F96 Q97 R128 D133 F137 R192 R194 E197 I11 A12 K15 E34 W39 L54 M57 Y58 F68 Q69 R100 D105 F109 R164 R166 E169 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTQDENGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqj A 3.70 BS03 MG A 1 E127 R192 E99 R164 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTQDENGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqj B 3.70 BS01 UDP B 1 N29 A31 A32 G33 K34 S35 T36 E127 R188 L191 R192 D241 F242 K243 N10 A12 A13 G14 K15 S16 T17 E95 R156 L159 R160 D209 F210 K211 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqj B 3.70 BS02 UMP B 1 I30 K34 E53 V55 W58 L82 M85 Y86 F96 Q97 R128 D133 F137 R192 R194 E197 I11 K15 E34 V36 W39 L50 M53 Y54 F64 Q65 R96 D101 F105 R160 R162 E165 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqj B 3.70 BS03 MG B 1 S35 E53 E127 R194 S16 E34 E95 R162 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqj C 3.70 BS03 MG C 1 S35 E53 V55 E127 R192 S16 E34 V36 E97 R162 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqj D 3.70 BS03 MG D 1 E53 E127 R194 E34 E96 R163 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mql A 3.25 BS02 G65 A 1 E53 V55 L82 M85 Y86 P89 E90 F96 Q97 D133 F137 S144 E145 C146 Y204 E35 V37 L53 M56 Y57 P60 E61 F67 Q68 D104 F108 S115 E116 C117 Y175 2.7.1.74 P27707 29127277 TRIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mql B 3.25 BS02 DCM B 1 I30 K34 E53 W58 Y86 F96 Q97 E127 R128 D133 F137 R192 R194 E197 I10 K14 E33 W38 Y53 F63 Q64 E94 R95 D100 F104 R159 R161 E164 2.7.1.74 P27707 29127277 IKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mql C 3.25 BS02 UDP C 1 A31 A32 G33 K34 S35 T36 E127 R188 R192 D241 F242 K243 A13 A14 G15 K16 S17 T18 E95 R156 R160 D209 F210 K211 2.7.1.74 P27707 29127277 TRIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mql C 3.25 BS03 DCM C 1 I30 E53 W58 Y86 F96 Q97 E127 R128 D133 F137 R192 R194 E197 I12 E35 W40 Y54 F64 Q65 E95 R96 D101 F105 R160 R162 E165 2.7.1.74 P27707 29127277 TRIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqt A 3.20 BS02 STI A 1 V55 M85 Y86 P89 E90 F96 Q97 R128 F137 S144 C146 V36 M55 Y56 P59 E60 F66 Q67 R98 F107 S114 C116 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqt B 3.20 BS03 DCM B 1 I30 K34 E53 W58 L82 Y86 F96 Q97 R128 F137 R192 R194 E197 I11 K15 E34 W39 L51 Y55 F65 Q66 R97 F106 R161 R163 E166 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSNVQSTNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqt C 3.20 BS02 STI C 1 I30 E53 V55 L82 M85 Y86 P89 E90 F96 Q97 R128 F137 S144 E197 Y204 I12 E35 V37 L52 M55 Y56 P59 E60 F66 Q67 R98 F107 S114 E167 Y174 2.7.1.74 P27707 29127277 TRIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5mqt D 3.20 BS02 DCM D 1 I30 K34 E53 V55 A56 F96 Q97 E127 R128 F137 R194 E197 I11 K15 E34 V36 A37 F62 Q63 E93 R94 F103 R160 E163 2.7.1.74 P27707 29127277 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 5n6c A 2.30 BS01 NAD A 1 T78 G152 G154 R155 I156 Y174 D175 P176 I177 H206 T207 P208 T213 C234 A235 R236 D260 H283 G285 A286 T72 G146 G148 R149 I150 Y168 D169 P170 I171 H200 T201 P202 T207 C228 A229 R230 D254 H277 G279 A280 1.1.1.95 O43175 AKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDM 5nl9 A 1.90 BS01 ZN A 1 H36 D84 H90 H92 D103 H37 D85 H91 H93 D104 Q72QS5 SMKDSYERSKKILEDAGINVTVQRLQMANLLLSKPQHLTADQVFQLINEHMPNASRATIFNNLKLFAEKGIVNLLELKSGITLYDSNVIHHHHAIDEKTGEIYDISLDSKLQEKVLSELKQDFKLKTGSSLENCNLSITLKGKKNP 5nl9 B 1.90 BS01 ZN B 1 H90 H92 D103 H91 H93 D104 Q72QS5 SMKDSYERSKKILEDAGINVTVQRLQMANLLLSKPQHLTADQVFQLINEHMPNASRATIFNNLKLFAEKGIVNLLELKSGITLYDSNVIHHHHAIDEKTGEIYDISLDSKLQEKVLSELKQDFKLKTGSSLENCNLSITLKGKKNP 5nwi A 2.35 BS01 III P 1 K56 R63 R67 K129 R136 Y137 G178 L181 N182 V185 Y188 L229 N233 L236 W237 K53 R60 R64 K126 R133 Y134 G175 L178 N179 V182 Y185 L226 N230 L233 W234 Q5KTN5 28970335 APTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQD 5nwj A 2.07 BS01 III P 1 K56 R63 R67 K129 R136 Y137 L181 N182 V185 Y188 E189 L229 N233 D240 K53 R60 R64 K126 R133 Y134 L178 N179 V182 Y185 E186 L226 N230 D237 P93343 28970335 APTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQD 5nwk A 3.30 BS01 III P 1 K56 R63 K129 R136 Y137 N182 V185 L229 N233 K52 R59 K125 R132 Y133 N178 V181 L225 N229 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQD 5nwk A 3.30 BS02 FSC A 1 E19 N49 L50 V53 F126 K129 P174 K221 D222 I226 E15 N45 L46 V49 F122 K125 P170 K217 D218 I222 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQD 5nwk B 3.30 BS01 III Q 1 K56 R63 K129 R136 Y137 N182 V185 Y188 N233 L236 W237 K56 R63 K129 R136 Y137 N182 V185 Y188 N233 L236 W237 Q5KTN5 28970335 MAVAPTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQDDG 5nwk B 3.30 BS02 FSC B 1 E19 N49 L50 S52 V53 F126 K129 P174 D222 I226 E19 N49 L50 S52 V53 F126 K129 P174 D222 I226 Q5KTN5 28970335 MAVAPTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQDDG 5nwk C 3.30 BS02 FSC C 1 E46 N49 L50 V53 F126 K129 K221 D222 I226 E40 N43 L44 V47 F120 K123 K215 D216 I220 Q5KTN5 28970335 AREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSD 5nwk D 3.30 BS01 III S 1 K56 R63 R67 K129 R136 Y137 L181 N182 V185 Y188 L229 N233 W237 K52 R59 R63 K125 R132 Y133 L177 N178 V181 Y184 L225 N229 W233 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSD 5nwk D 3.30 BS02 FSC D 1 E19 E46 N49 L50 V53 F126 K129 D222 I226 E15 E42 N45 L46 V49 F122 K125 D218 I222 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSD 5nwk E 3.30 BS01 III T 1 K56 R63 K129 D133 R136 Y137 L181 N182 V185 Y188 E189 I226 N233 W237 K54 R61 K127 D131 R134 Y135 L179 N180 V183 Y186 E187 I224 N231 W235 Q5KTN5 28970335 VAPTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSD 5nwk E 3.30 BS02 FSC E 1 E19 N49 S52 V53 F126 K129 K221 D222 I226 E17 N47 S50 V51 F124 K127 K219 D220 I224 Q5KTN5 28970335 VAPTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSD 5nwk F 3.30 BS01 III U 1 K56 R63 R67 K129 R136 Y137 L181 N182 V185 N233 W237 K52 R59 R63 K125 R132 Y133 L177 N178 V181 N229 W233 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDM 5nwk G 3.30 BS01 III V 1 R63 R67 K129 R136 Y137 N182 V185 Y188 N233 L236 W237 D243 R59 R63 K125 R132 Y133 N178 V181 Y184 N224 L227 W228 D234 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELESYKDSTLIMQLLRDNLTLWTSDMQD 5nwk G 3.30 BS02 FSC G 1 N49 V53 K56 F126 K129 P174 D222 I226 N45 V49 K52 F122 K125 P170 D213 I217 Q5KTN5 28970335 PTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELESYKDSTLIMQLLRDNLTLWTSDMQD 5ogk A 3.60 BS01 GDD A 1 Y28 S32 M35 Y114 N220 N221 I265 S266 S269 Y281 G285 A286 K289 Y10 S14 M17 Y93 N179 N180 I224 S225 S228 Y240 G244 A245 K248 P40107 NSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQ 5ogk D 3.60 BS01 GDD D 1 Y28 M35 M98 Y114 M202 N220 N221 I265 S266 S269 G270 Y281 K289 Y11 M18 M78 Y94 M163 N181 N182 I226 S227 S230 G231 Y242 K250 P40107 ANSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQ 5ogk E 3.60 BS01 GDD E 1 Y28 M35 Y114 N221 I265 S269 Y281 K289 Y11 M18 Y94 N186 I230 S234 Y246 K254 P40107 ANSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVASFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQ 5ojg A 1.90 BS01 NAP A 1 A17 T19 K20 G21 I22 S41 R42 N43 N46 G67 I69 N95 H96 G97 N146 A147 S148 Y161 K165 P191 G192 I194 T196 K197 M198 S199 A17 T19 K20 G21 I22 S41 R42 N43 N46 G67 I69 N95 H96 G97 N146 A147 S148 Y161 K165 P191 G192 I194 T196 K197 M198 S199 1.1.1.184 G5EGA6 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 5ojg A 1.90 BS02 BUO A 1 S148 S150 I158 Y161 M198 S148 S150 I158 Y161 M198 1.1.1.184 G5EGA6 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 5ojg B 1.90 BS02 BUO B 1 S148 Y149 S150 Y161 S148 Y149 S150 Y161 1.1.1.184 G5EGA6 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 5oji A 1.60 BS02 ISN A 1 S148 S150 Y161 V193 M198 S199 L202 Q217 S148 S150 Y161 V193 M198 S199 L202 Q217 1.1.1.184 G5EGA6 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 5oji B 1.60 BS02 ISN B 1 S148 Y149 I158 Y161 P191 G192 V193 M198 S199 L202 S148 Y149 I158 Y161 P191 G192 V193 M198 S199 L202 1.1.1.184 G5EGA6 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITGEMIIIAGGVQARL 5ong A 2.80 BS01 NUC I 1 C40 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 C2 Y3 R4 P5 T7 R25 R34 R45 F46 Q47 S48 R78 V79 T80 M82 P84233 29113904 HCYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGER 5ong A 2.80 BS02 NUC J 1 H39 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 P66 R69 R83 H1 Y3 P5 G6 T7 V8 A9 R11 R25 K26 L27 P28 R31 R45 P84233 29113904 HCYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGER 5ong D 2.80 BS02 NUC J 1 K28 R30 K31 S33 I36 Y37 K1 R3 K4 S6 I9 Y10 P02281 29113904 KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5ong E 2.80 BS01 NUC I 1 Y41 G44 T45 V46 A47 R49 R63 K64 L65 R69 R83 Y3 G6 T7 V8 A9 R11 R25 K26 L27 R31 R45 P84233 29113904 HCYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGERA 5onw D 2.80 BS01 NUC I 1 R26 R27 T29 S52 S53 R83 S84 T85 R1 R2 T4 S27 S28 R58 S59 T60 P02281 29113904 RRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5onw D 2.80 BS02 NUC J 1 R26 T29 R30 K31 E32 S33 Y37 R1 T4 R5 K6 E7 S8 Y12 P02281 29113904 RRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5onw E 2.80 BS01 NUC I 1 H39 Y41 P43 G44 V46 A47 R49 R63 K64 L65 R69 R83 H1 Y3 P5 G6 V8 A9 R11 R25 K26 L27 R31 R45 P84233 29113904 HCYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGE 5onw E 2.80 BS02 NUC J 1 C40 R42 P43 T45 R72 R83 F84 Q85 S86 R116 V117 T118 M120 C2 R4 P5 T7 R34 R45 F46 Q47 S48 R78 V79 T80 M82 P84233 29113904 HCYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGE 5onw G 2.80 BS02 NUC J 1 A14 R17 G28 R29 R32 R42 R77 A1 R4 G15 R16 R19 R29 R64 Q6AZJ8 29113904 AKTRSSRAGLQFPVGRVHRLLRKGCYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVLLPK 5ovr A 2.15 BS01 AXK A 1 N376 E378 E379 S434 W435 P436 D437 K439 R443 R478 Q520 N126 E128 E129 S184 W185 P186 D187 K189 R193 R228 Q270 3.1.3.48 P54829 29116812 NLYFQSMSRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSH 5ow1 A 2.05 BS01 AY8 A 1 Y304 I307 W435 K439 A474 R478 Q516 T517 Q520 Y54 I57 W182 K186 A221 R225 Q263 T264 Q267 3.1.3.48 P54829 29116812 NLYFQSMSRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSH 5p9n A 1.17 BS02 7JE A 1 W38 M40 G66 M89 E90 I91 A118 S119 Q120 D141 H142 W143 K144 R146 D169 N170 V173 P174 L198 E199 W36 M38 G64 M87 E88 I89 A116 S117 Q118 D139 H140 W141 K142 R144 D167 N168 V171 P172 L196 E197 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5p9o A 1.10 BS01 7JF A 1 W38 M40 D141 H142 W143 D169 N170 V173 P174 L198 E199 W36 M38 D139 H140 W141 D167 N168 V171 P172 L196 E197 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5p9o A 1.10 BS02 SAH A 1 M40 N41 V42 G66 A67 Y68 Y71 S72 E90 I91 G117 A118 S119 Q120 D141 H142 R146 M38 N39 V40 G64 A65 Y66 Y69 S70 E88 I89 G115 A116 S117 Q118 D139 H140 R144 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5p9r A 1.70 BS02 SAH A 1 M40 V42 G66 A67 Y68 Y71 S72 E90 I91 G117 A118 S119 Q120 D141 H142 R146 M39 V41 G65 A66 Y67 Y70 S71 E89 I90 G116 A117 S118 Q119 D140 H141 R145 2.1.1.6 P22734 GDTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5p9s A 2.30 BS03 7JK A 1 W38 M40 D141 H142 W143 D169 N170 V173 L198 E199 M201 W36 M38 D139 H140 W141 D167 N168 V171 L196 E197 M199 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGPS 5p9w A 1.43 BS02 7JN A 1 W38 M40 E90 M91 N92 Y95 G117 A118 S119 Q120 D141 H142 W143 K144 R146 D169 N170 V173 P174 L198 E199 W36 M38 E88 M89 N90 Y93 G115 A116 S117 Q118 D139 H140 W141 K142 R144 D167 N168 V171 P172 L196 E197 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEMNPDYAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5p9x A 1.12 BS02 7JO A 1 W38 M40 G66 Y68 E90 I91 G117 A118 S119 Q120 D141 H142 W143 K144 D169 N170 V173 P174 L198 E199 W36 M38 G64 Y66 E88 I89 G115 A116 S117 Q118 D139 H140 W141 K142 D167 N168 V171 P172 L196 E197 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5p9y A 1.20 BS02 7JP A 1 W38 M40 G66 M89 E90 I91 A118 S119 D141 H142 W143 D169 N170 V173 P174 L198 E199 W36 M38 G64 M87 E88 I89 A116 S117 D139 H140 W141 D167 N168 V171 P172 L196 E197 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5pa0 A 1.26 BS01 SAH A 1 M40 N41 V42 E64 G66 A67 Y68 Y71 S72 M89 E90 I91 N92 G117 A118 S119 Q120 D141 H142 W143 R146 M38 N39 V40 E62 G64 A65 Y66 Y69 S70 M87 E88 I89 N90 G115 A116 S117 Q118 D139 H140 W141 R144 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5pa0 A 1.26 BS02 7JR A 1 W38 M40 D141 W143 K144 D169 N170 P174 L198 E199 W36 M38 D139 W141 K142 D167 N168 P172 L196 E197 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5pa3 A 1.60 BS01 SAH A 1 M40 N41 V42 G66 A67 Y68 Y71 S72 E90 I91 N92 C95 G117 A118 S119 Q120 D141 H142 M38 N39 V40 G64 A65 Y66 Y69 S70 E88 I89 N90 C93 G115 A116 S117 Q118 D139 H140 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5pa6 A 1.29 BS01 SAH A 1 M40 N41 V42 G66 A67 Y68 Y71 S72 M89 E90 I91 G117 A118 S119 Q120 D141 H142 W143 M38 N39 V40 G64 A65 Y66 Y69 S70 M87 E88 I89 G115 A116 S117 Q118 D139 H140 W141 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5pa7 A 2.12 BS01 SAH A 1 M40 N41 V42 G66 A67 Y68 Y71 S72 M89 E90 I91 C95 G117 A118 S119 D141 H142 W143 M38 N39 V40 G64 A65 Y66 Y69 S70 M87 E88 I89 C93 G115 A116 S117 D139 H140 W141 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5pa7 A 2.12 BS03 7JX A 1 M40 D141 H142 W143 K144 D169 N170 P174 M201 M38 D139 H140 W141 K142 D167 N168 P172 M199 2.1.1.6 P22734 DTKEQRILRYVQQNAKPGDPQSVLEAIDTYCTQKEWAMNVGDAKGQIMDAVIREYSPSLVLELGAYCGYSAVRMARLLQPGARLLTMEINPDCAAITQQMLNFAGLQDKVTILNGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEKCGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAIYQGP 5t1h A 2.11 BS01 75E A 1 L45 V53 V66 K68 I95 F113 E114 H115 V116 N118 M163 I174 D175 L44 V52 V65 K67 I94 F112 E113 H114 V115 N117 M162 I173 D174 2.7.11.1 P68400 SGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQA 5tv1 A 2.40 BS01 IHP A 1 T226 K227 R332 T219 K220 R320 P32120 29127291 RVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKP 5tv1 A 2.40 BS02 IHP A 2 K233 R237 K251 K325 K327 K226 R230 K244 K313 K315 P32120 29127291 RVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKP 5twl A 2.42 BS01 H91 A 1 I17 G18 A38 K40 E57 L61 C70 L86 E87 C89 E93 E136 N137 L139 I149 D150 I18 G19 A39 K41 E58 L62 C71 L87 E88 C90 E94 E137 N138 L140 I150 D151 2.7.11.1,2.7.10.2 Q14680 GSKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 5twy A 2.91 BS01 7LY A 1 I17 V25 L27 A38 C70 L86 E87 C89 P90 E93 I149 I18 V26 L28 A39 C68 L84 E85 C87 P88 E91 I147 2.7.11.1,2.7.10.2 Q14680 GSKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCGSLAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 5twy B 2.91 BS01 7LY B 1 V25 A38 E87 C89 P90 I149 V23 A36 E81 C83 P84 I143 2.7.11.1,2.7.10.2 Q14680 GSKDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCLAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRL 5twz A 2.63 BS01 45R A 1 I17 L27 A38 C70 L86 E87 Y88 C89 P90 L139 I149 D150 I17 L24 A35 C67 L83 E84 Y85 C86 P87 L136 I146 D147 2.7.11.1,2.7.10.2 Q14680 SKDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 5tx3 A 2.90 BS01 7MY A 1 V25 A38 K40 L86 E87 Y88 C89 P90 G92 E93 E136 L139 I149 V25 A38 K40 L78 E79 Y80 C81 P82 G84 E85 E128 L131 I141 2.7.11.1,2.7.10.2 Q14680 SGSMKDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLGSLAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 5tx3 B 2.90 BS01 7MY B 1 I17 V25 K40 L86 E87 Y88 C89 G92 E93 E136 L139 I149 I20 V23 K38 L74 E75 Y76 C77 G80 E81 E124 L127 I137 2.7.11.1,2.7.10.2 Q14680 SGSMKDYDELLKYYELHETIGKVKLACHILTGEMVAIKIMDKKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDGSLAYAAPELIQGLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLRL 5u7n A 2.30 BS01 CU A 1 H114 C149 H152 M155 H66 C101 H104 M107 1.9.3.1,1.9.3.1 P98052 KLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVEVLPGEVSTVRYTFKRPGEYRIICTPHPFMFGTIVVKE 5ua1 B 2.90 BS01 NUC C 1 Q38 M39 R40 Y54 S59 K60 Q30 M31 R32 Y46 S51 K52 P96856 LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIG 5ua1 B 2.90 BS02 NUC D 1 Q14 R17 R40 D47 V48 A49 T52 Y56 Q6 R9 R32 D39 V40 A41 T44 Y48 P96856 LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIG 5ua1 B 2.90 BS04 NUC F 1 Q38 M39 R40 V50 Y54 S59 K60 Q30 M31 R32 V42 Y46 S51 K52 P96856 LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIG 5ua1 A 2.90 BS01 NUC C 1 R17 R40 D47 V48 A49 T52 R55 Y56 R9 R32 D39 V40 A41 T44 R47 Y48 P96856 LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIG 5uih A 1.65 BS01 8CV A 1 I5 A6 A7 M16 D27 L28 F31 I94 Y100 I5 A6 A7 M16 D27 L28 F31 I94 Y100 1.5.1.3 P0ABQ4 28766937 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio A 1.93 BS01 LG3 A 1 I5 A6 A7 D27 F31 I94 T113 I6 A7 A8 D28 F32 I95 T114 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio A 1.93 BS02 8DM A 1 F31 K32 I50 R52 R57 F32 K33 I51 R53 R58 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio B 1.93 BS01 LG3 B 1 I5 A6 A7 D27 F31 I94 Y100 T113 I6 A7 A8 D28 F32 I95 Y101 T114 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio C 1.93 BS02 8DM C 1 L28 F31 K32 I50 R52 L54 R57 L29 F32 K33 I51 R53 L55 R58 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio D 1.93 BS02 8DM D 1 M20 L28 F31 K32 I50 L54 R57 M21 L29 F32 K33 I51 L55 R58 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio D 1.93 BS03 NAP D 1 A6 A7 I14 G15 N18 A19 W22 G43 R44 H45 T46 L62 S63 S64 K76 I94 G95 G96 G97 R98 V99 Y100 Q102 A7 A8 I15 G16 N19 A20 W23 G44 R45 H46 T47 L63 S64 S65 K77 I95 G96 G97 G98 R99 V100 Y101 Q103 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio E 1.93 BS02 8DM E 1 L28 F31 K32 I50 R52 R57 L29 F32 K33 I51 R53 R58 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uio E 1.93 BS03 NAP E 1 E17 G43 R44 H45 T46 L62 S63 S64 K76 G96 G97 R98 V99 Q102 D122 T123 E18 G44 R45 H46 T47 L63 S64 S65 K77 G97 G98 R99 V100 Q103 D123 T124 1.5.1.3 P0ABQ4 28766937 MMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5uip B 1.90 BS01 8DM B 1 F31 I50 R52 R57 F31 I50 R52 R57 1.5.1.3 P0ABQ4 28766937 GISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYSFEILERR 5ur6 A 1.63 BS01 8KM A 1 F61 I62 V81 V83 L87 A89 S92 E94 F108 I110 L117 Y120 F159 V163 F60 I61 V80 V82 L86 A88 S91 E93 F107 I109 L116 Y119 F151 V155 O49686 28949512 PSELTPEERSELKNSIAEFHTYQLDPGSCSSLHAQRIHAPPELVWSIVRRFDKPQTYKHFIKSCSVEQNFEMRVGCTRDVIVISGLPANTSTERLDILDDERRVTGFSIIGGEHRLTNYKSVTTVHRFEKENRIWTVVLESYVVDMDTRMFADTVVKLNLQKLATVAEAMARN 5va4 A 2.31 BS01 ZN A 1 C107 D110 H124 H127 C14 D17 H31 H34 6.1.1.11 Q68KK2 DHCAHHGEKLVLFCQQDGNVICWLCERSQEHRGHQTFLVEEVAQKYREKLQVALEMMRQKQKDAETECNQVAKRVALIARGKACGEQTQSVRVLISDLEHRLQGSVMELLQGVDGVIKRIEKV 5va4 A 2.31 BS02 ZN A 2 C96 H99 C115 C118 C3 H6 C22 C25 6.1.1.11 Q68KK2 DHCAHHGEKLVLFCQQDGNVICWLCERSQEHRGHQTFLVEEVAQKYREKLQVALEMMRQKQKDAETECNQVAKRVALIARGKACGEQTQSVRVLISDLEHRLQGSVMELLQGVDGVIKRIEKV 5va4 A 2.31 BS03 ZN A 3 E158 C161 C186 E65 C68 C84 6.1.1.11 Q68KK2 DHCAHHGEKLVLFCQQDGNVICWLCERSQEHRGHQTFLVEEVAQKYREKLQVALEMMRQKQKDAETECNQVAKRVALIARGKACGEQTQSVRVLISDLEHRLQGSVMELLQGVDGVIKRIEKV 5vvr A 5.80 BS01 NUC R 1 F252 R320 D483 G484 D485 F245 R313 D476 G477 D478 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMP 5vvr A 5.80 BS02 NUC T 1 T44 Q45 K145 S255 Q256 R257 K332 R337 R344 T831 A832 Y836 R839 R1386 T37 Q38 K138 S248 Q249 R250 K325 R330 R337 T824 A825 Y829 R832 R1379 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMP 5vvr A 5.80 BS03 ZN A 1 C107 M108 C110 G165 G166 C167 C100 M101 C103 G158 G159 C160 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMP 5vvr B 5.80 BS01 NUC N 1 F250 I251 R430 R434 I502 G503 R504 F233 I234 R413 R417 I485 G486 R487 2.7.7.6 P08518 FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5vvr B 5.80 BS02 NUC R 1 A477 K775 K987 H1097 A460 K758 K970 H1080 2.7.7.6 P08518 FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5vvr B 5.80 BS03 NUC T 1 M792 Y866 E923 R1122 S1123 R1129 M775 Y849 E906 R1105 S1106 R1112 2.7.7.6 P08518 FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5vvr C 5.80 BS01 ZN C 1 E81 C86 C88 C92 C95 E81 C86 C88 C92 C95 P16370 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKV 5vvr I 5.80 BS01 ZN I 1 C7 C10 N12 C29 C32 C7 C10 N12 C29 C32 P27999 MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQFS 5vvr L 5.80 BS01 ZN L 1 C31 C34 D50 C51 C7 C10 D26 C27 P40422 ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR 5vvr M 5.80 BS01 NUC N 1 R452 H472 I474 R475 N476 I481 R731 W752 N753 R791 K795 R171 H191 I193 R194 N195 I200 R437 W458 N459 R497 K501 3.6.4.12 P40352 LRFRGQPGEAKDDGDELYYQERLKKWVKQRSCGSQRSSDLPEWRRPHPNIPDAKLNSQFKIPGEIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVLFCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDGDPKRSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFNNESFDVFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQF 5vvr M 5.80 BS02 NUC T 1 R230 G612 K613 R614 N615 L617 F618 S676 R677 R731 R2 G331 K332 R333 N334 L336 F337 S382 R383 R437 3.6.4.12 P40352 LRFRGQPGEAKDDGDELYYQERLKKWVKQRSCGSQRSSDLPEWRRPHPNIPDAKLNSQFKIPGEIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVLFCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDGDPKRSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFNNESFDVFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQF 5vvs A 6.40 BS02 NUC N 1 A1108 R1391 A1101 R1384 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEI 5vvs A 6.40 BS03 NUC T 1 R320 K332 R350 P448 T831 A832 G835 Y836 R1386 R313 K325 R343 P441 T824 A825 G828 Y829 R1379 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEI 5vvs A 6.40 BS04 ZN A 1 C107 M108 C110 C100 M101 C103 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEI 5vvs A 6.40 BS05 ZN A 2 C67 E72 C77 P78 C60 E65 C70 P71 2.7.7.6 P04050 SAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEI 5vvs B 6.40 BS01 NUC R 1 E529 K775 K987 E512 K758 K970 2.7.7.6 P08518 FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5vvs B 6.40 BS02 NUC T 1 D505 R942 R1129 D488 R925 R1112 2.7.7.6 P08518 FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5vvs B 6.40 BS03 ZN B 1 C1163 I1165 C1166 L1168 C1182 C1146 I1148 C1149 L1151 C1165 2.7.7.6 P08518 FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5vvs C 6.40 BS01 ZN C 1 C86 C88 C92 D93 K94 C86 C88 C92 D93 K94 P16370 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKV 5vvs I 6.40 BS01 ZN I 1 N12 C29 C32 N12 C29 C32 P27999 MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQFS 5vvs I 6.40 BS02 ZN I 2 C103 S105 C106 C103 S105 C106 P27999 MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQFS 5vvs L 6.40 BS01 ZN L 1 C31 A32 C34 C51 C7 A8 C10 C27 P40422 ATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR 5vx6 A 3.20 BS01 C2E A 1 R99 R100 Q101 R104 N127 G131 G132 I133 A134 R171 R172 T185 L186 E187 R98 R99 Q100 R103 N124 G128 G129 I130 A131 R168 R169 T182 L183 E184 P38491 IEIGENVLLEYIEENELKKAKSKAVSIENNELLIAYPVDVVTGRTVILHNDMEVTVEFVGKDEVPYRFISRIKGKVKDKLQMICLEMPPREKMKRIQRRQYVRTDAVLDVQIQPEEEIRTLSYNISAGGIAVVLADGLSFQSGESLRLIIRLPEEEHTRQIETEAVVRRIFNDPKSEKRKMTLEYSEIAAGDQQALLQYCIRRQLNKRR 5vx6 A 3.20 BS02 C2E A 2 V60 E64 P66 Q98 R99 R100 R104 R172 V59 E63 P65 Q97 R98 R99 R103 R169 P38491 IEIGENVLLEYIEENELKKAKSKAVSIENNELLIAYPVDVVTGRTVILHNDMEVTVEFVGKDEVPYRFISRIKGKVKDKLQMICLEMPPREKMKRIQRRQYVRTDAVLDVQIQPEEEIRTLSYNISAGGIAVVLADGLSFQSGESLRLIIRLPEEEHTRQIETEAVVRRIFNDPKSEKRKMTLEYSEIAAGDQQALLQYCIRRQLNKRR 5vx6 B 3.20 BS01 C2E B 1 R99 R100 Q101 R104 N127 G131 G132 I133 A134 T185 L186 E187 R100 R101 Q102 R105 N125 G129 G130 I131 A132 T183 L184 E185 P38491 MGIEIGENVLLEYIEENELKKAKSKAVSIENNELLIAYPVDVVTGRTVILHNDMEVTVEFVGKDEVPYRFISRIKGKVKDKLQMICLEMPPREKMKRIQRRQYVRTDAVLDVQIQEEEIRTLSYNISAGGIAVVLADGLSFQSGESLRLIIRLPEEEHTRQIETEAVVRRIFNDPKSEKRKMTLEYSEIAAGDQQALLQYCIRRQLNKR 5vx6 B 3.20 BS02 C2E B 2 V60 V65 P66 Q98 R99 R100 R104 R172 V61 V66 P67 Q99 R100 R101 R105 R170 P38491 MGIEIGENVLLEYIEENELKKAKSKAVSIENNELLIAYPVDVVTGRTVILHNDMEVTVEFVGKDEVPYRFISRIKGKVKDKLQMICLEMPPREKMKRIQRRQYVRTDAVLDVQIQEEEIRTLSYNISAGGIAVVLADGLSFQSGESLRLIIRLPEEEHTRQIETEAVVRRIFNDPKSEKRKMTLEYSEIAAGDQQALLQYCIRRQLNKR 5w1j A 2.70 BS01 FAD A 1 I115 G116 G117 G118 S119 G120 D139 F140 G154 T155 C156 V159 G160 C161 K164 L227 G228 A256 T257 G258 S276 Y296 V297 R393 I400 G431 D432 Q439 L440 T441 P442 I109 G110 G111 G112 S113 G114 D133 F134 G148 T149 C150 V153 G154 C155 K158 L221 G222 A250 T251 G252 S270 Y290 V291 R387 I394 G425 D426 Q433 L434 T435 P436 Q869D7 28463568 SAEQVEKLRNKINNAAVLVFAKSFCPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFIGGCDDVMAIDDDTIVKKANEMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLMHQAALLNHYMEDAKSFGWDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTLDHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVRSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADDCRTDYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRPDNTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETFTTLRVTKSSGASA 5w1j A 2.70 BS02 FAD B 1 H570 P571 H564 P565 Q869D7 28463568 SAEQVEKLRNKINNAAVLVFAKSFCPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFIGGCDDVMAIDDDTIVKKANEMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLMHQAALLNHYMEDAKSFGWDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTLDHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVRSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADDCRTDYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRPDNTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETFTTLRVTKSSGASA 5w1l A 2.88 BS01 FAD A 1 I115 G116 G118 S119 G120 D139 F140 G154 T155 G160 C161 K164 A226 L227 G228 A256 T257 G258 Y296 V297 R393 I400 G431 D432 Q439 L440 T441 P442 I109 G110 G112 S113 G114 D133 F134 G148 T149 G154 C155 K158 A220 L221 G222 A250 T251 G252 Y290 V291 R387 I394 G425 D426 Q433 L434 T435 P436 Q869D7 28463568 SAEQVEKLRNKINNAAVLVFAKSFCPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFIGGCDDVMAIDDDTIVKKANEMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLMHQAALLNHYMEDAKSFGWDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTLDHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVRSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADDCRTDYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRPDNTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETFTTLRVTKSSGASA 5w1l A 2.88 BS02 AU A 1 F504 P506 C519 P541 C573 F498 P500 C513 P535 C567 Q869D7 28463568 SAEQVEKLRNKINNAAVLVFAKSFCPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFIGGCDDVMAIDDDTIVKKANEMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLMHQAALLNHYMEDAKSFGWDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTLDHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVRSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADDCRTDYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRPDNTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETFTTLRVTKSSGASA 5w1l B 2.88 BS01 FAD B 1 I115 G116 G117 G118 S119 G120 L138 D139 F140 V141 G154 T155 C156 G160 C161 K164 A226 L227 G228 A256 T257 G258 Y296 R393 I400 G431 D432 Q439 L440 T441 P442 I109 G110 G111 G112 S113 G114 L132 D133 F134 V135 G148 T149 C150 G154 C155 K158 A220 L221 G222 A250 T251 G252 Y290 R387 I394 G425 D426 Q433 L434 T435 P436 Q869D7 28463568 SAEQVEKLRNKINNAAVLVFAKSFCPYCKKVMERFNNLKIPFGYLDLDLKKNGSDYQKMLQEITGRTTVPQVFFRGEFIGGCDDVMAIDDDTIVKKANEMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLMHQAALLNHYMEDAKSFGWDVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYGITSDDLFTLDHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVRSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADDCRTDYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRPDNTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETFTTLRVTKSSGASA 5w99 A 1.59 BS01 A1V A 1 E169 G174 V177 S178 S181 H182 L266 N269 T271 W272 V276 F282 R286 I328 G331 E168 G173 V176 S177 S180 H181 L254 N257 T259 W260 V264 F270 R274 I316 G319 U5Q3T2 TWRRFDVAYHDPDLDRLILAARPLLSESPGRSWFQRHWVRGPHLELWFDHPEPSWERVREVLGTHLRAHPSRTRIDPDRLLPQHRRLALAEQIDEPLLPFYDDNTLHRAVPRSRVHVLGSAAAEDLFHDFHAAASTAAFDQLDAVVAGESRLGLAFELMIAAAHAHAEGGITGGFVSFRSHAEAFLAGAAGLRERWEAEYRTRAEALRAQVAAVVTGTPRGRAWTGLLDGFAGRGDELIASGALTPDTEFHRALRANRTWHDEVLRSPSFRRYRLLLNLTYLQMSRLGVTAVQRSLLCHFAASAVEEEYGVSAIEIAVG 5wa4 A 2.65 BS01 III M 1 A159 S160 P162 T163 F166 H212 R215 N216 A219 F220 R223 L240 L334 L338 A155 S156 P158 T159 F162 H208 R211 N212 A215 F216 R219 L236 L294 L298 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAENGAHLPHVREWVRRLRPIRERARALLESGELTDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 A 2.65 BS02 III O 1 G348 I349 A350 G308 I309 A310 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAENGAHLPHVREWVRRLRPIRERARALLESGELTDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 A 2.65 BS03 III P 1 G109 P110 G105 P106 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAENGAHLPHVREWVRRLRPIRERARALLESGELTDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 B 2.65 BS01 III N 1 A159 S160 P162 T163 L208 H212 N216 A219 F220 R223 L338 A155 S156 P158 T159 L204 H208 N212 A215 F216 R219 L295 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESHLPHVREWVRRLRPIRERARALLESGELTLEDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 B 2.65 BS02 III R 1 D108 G109 P110 D104 G105 P106 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESHLPHVREWVRRLRPIRERARALLESGELTLEDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 C 2.65 BS01 III M 1 G348 A350 G306 A308 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAHLPHVREWVRRLRPIRERARALLESGELTLEDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 C 2.65 BS02 III O 1 A159 S160 P162 T163 F166 H212 R215 N216 F220 R223 V335 L338 A155 S156 P158 T159 F162 H208 R211 N212 F216 R219 V293 L296 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAHLPHVREWVRRLRPIRERARALLESGELTLEDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 E 2.65 BS02 III Q 1 A159 S160 P162 T163 F166 L208 W209 H212 R215 N216 A219 F220 R223 L338 A155 S156 P158 T159 F162 L204 W205 H208 R211 N212 A215 F216 R219 L301 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAENGAHLPHVREWVRRLRPIRERARALLESGELTLERDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wa4 F 2.65 BS01 III R 1 P162 T163 F166 L208 H212 R215 N216 A219 F220 R223 L338 P158 T159 F162 L204 H208 R211 N212 A215 F216 R219 L296 D6Y504 ERWWRFRVDYHAGPMDDLILDGVRPAFAAFAAQAPMAYFLRHWRRGPHLRIYVSTTREALEAVVRPAIEHVVGGYLRARPSPGMADPSAFLPLHERLAELEGEDGPLMPWSPDNTIHAEGERPEPLTVRDVLLADFYADTTPSVYHALERVRSGASLPTIAFDLVVATAHALSTGGLPVARTSLRSHAEAYLARRSDGVRLRELWRDHYARNREAFTERLIAVASSAESAAHLPHVREWVRRLRPIRERARALLESGELTRDSPAFGAYRLVINCTYLHLTRLGLTPHQRFLVCHLAADAAADVYGIA 5wc9 B 3.15 BS01 NUC C 1 R20 T26 Q27 Q44 T45 C48 R49 N52 Q54 R95 T96 I98 K103 V134 N141 R19 T25 Q26 Q43 T44 C47 R48 N51 Q53 R78 T79 I81 K86 V117 N124 P28069 DSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wc9 B 3.15 BS02 NUC D 1 E41 F42 S43 T45 T46 R49 S56 K58 N59 R94 R95 R143 Q144 K147 E40 F41 S42 T44 T45 R48 S55 K57 N58 R77 R78 R126 Q127 K130 P28069 DSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wc9 A 3.15 BS01 NUC C 1 R20 T26 Q27 Q44 T45 C48 R49 N52 Q54 R95 T96 I98 V134 V137 N141 R145 R19 T25 Q26 Q43 T44 C47 R48 N51 Q53 R81 T82 I84 V120 V123 N127 R131 P28069 DSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGAKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wc9 A 3.15 BS02 NUC D 1 E41 F42 S43 T45 T46 R49 S56 N59 L63 R94 R95 R143 Q144 K147 E40 F41 S42 T44 T45 R48 S55 N58 L62 R80 R81 R129 Q130 K133 P28069 DSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGAKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wc9 E 3.15 BS02 NUC H 1 E41 F42 S43 T45 T46 R49 S56 K58 N59 K62 K93 R94 R95 K115 R143 Q144 K147 E39 F40 S41 T43 T44 R47 S54 K56 N57 K60 K75 R76 R77 K97 R125 Q126 K129 P28069 SPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wc9 F 3.15 BS01 NUC G 1 R20 Q27 Q44 T45 C48 R49 E51 N52 Q54 R95 T96 T97 I98 K103 V134 N141 R19 Q26 Q43 T44 C47 R48 E50 N51 Q53 R77 T78 T79 I80 K85 V116 N123 P28069 DSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wc9 F 3.15 BS02 NUC H 1 E41 F42 S43 Q44 T45 T46 R49 S56 N59 K62 R94 R95 R143 Q144 E40 F41 S42 Q43 T44 T45 R48 S55 N58 K61 R76 R77 R125 Q126 P28069 DSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 5wea A 3.12 BS01 NUC B 1 F294 Y311 H316 T337 Y338 G524 T526 Y529 Q545 C546 V547 Q548 N551 T559 N562 L563 K566 K709 R714 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 R795 V797 S798 Y804 R812 F236 Y253 H258 T276 Y277 G456 T458 Y461 Q477 C478 V479 Q480 N483 T491 N494 L495 K498 K635 R640 H679 I682 Q683 T685 S686 R687 Y716 R718 C719 R721 V723 S724 Y730 R738 3.1.26.- Q9UKV8 28939659 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLIFKVSIKWVSCVSLQALHDALSGRVPFETIQALDVVMRHLPSMRYTPVGRSFFTASGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVPLTDSQRVKFTKEIKGLKVEITRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGKHTYLPLEVCNIVAGQRCIKSTAARATARSAPDRQEEISKLMRSADFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLHQALAKAVQVHQDTLRTMYFA 5wql C 2.30 BS01 III H 1 G396 G397 G398 L400 S452 A453 V480 Q481 Q482 Y483 G372 G373 G374 L376 S428 A429 V456 Q457 Q458 Y459 3.4.21.102 P23865 DITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGAGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKA 5wql C 2.30 BS02 III G 1 G247 I248 G249 A250 V251 L252 Q253 V304 I307 D342 G223 I224 G225 A226 V227 L228 Q229 V280 I283 D318 3.4.21.102 P23865 DITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGAGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKA 5wql D 2.30 BS01 III F 1 H225 G396 G397 G398 L400 S452 A453 Q481 Q482 Y483 H201 G372 G373 G374 L376 S426 A427 Q455 Q456 Y457 3.4.21.102 P23865 DITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGAGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKAR 5wql D 2.30 BS02 III E 1 G247 I248 G249 A250 V251 L252 V304 I307 K308 G223 I224 G225 A226 V227 L228 V280 I283 K284 3.4.21.102 P23865 DITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGAGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKAR 5wqx A 2.29 BS01 T65 A 1 C285 Q286 R288 S289 Y327 I341 S342 F363 M364 H449 L453 L469 Y473 C67 Q68 R70 S71 Y109 I123 S124 F145 M146 H231 L235 L251 Y255 P37231 29097031 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTDKSPFVIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 5wr0 A 2.85 BS01 8Y0 A 1 K263 R280 F282 G284 C285 Q286 F287 R288 S289 Y327 S342 M364 H449 L453 L465 Y473 K56 R62 F64 G66 C67 Q68 F69 R70 S71 Y109 S124 M146 H231 L235 L247 Y255 P37231 29097031 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTDKSPFVIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 5wr1 A 2.34 BS01 8XO A 1 F282 C285 Q286 S289 Y327 I341 M364 H449 Y473 F64 C67 Q68 S71 Y109 I123 M146 H231 Y255 P37231 29097031 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTDKSPFVIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKD 5wx9 A 1.76 BS01 NUC B 1 D2 Q3 R6 R19 R21 K25 R39 W41 T44 D2 Q3 R6 R19 R21 K25 R39 W41 T44 Q9LSX0 MDQGGRGVGAEHGKYRGVRRRPWGKYAAEIRDSRKHGERVWLGTFDTAEEAARAYDQAAYSMRGQAAILNFPHEYNMGSGVSSSTAMAGSSSASASASSSSRQVFEFEYLDDSVLEELLEEGEKPNKGKKK 5wx9 A 1.76 BS02 NUC C 1 M1 Q3 G4 G5 G7 V8 K14 R16 G17 V18 R19 R21 R31 S33 R39 K131 M1 Q3 G4 G5 G7 V8 K14 R16 G17 V18 R19 R21 R31 S33 R39 K131 Q9LSX0 MDQGGRGVGAEHGKYRGVRRRPWGKYAAEIRDSRKHGERVWLGTFDTAEEAARAYDQAAYSMRGQAAILNFPHEYNMGSGVSSSTAMAGSSSASASASSSSRQVFEFEYLDDSVLEELLEEGEKPNKGKKK 5wy2 A 1.90 BS01 III B 1 D34 I35 P36 D37 A38 L39 S40 M106 Y132 L133 F136 K137 V140 E144 D7 I8 P9 D10 A11 L12 S13 M79 Y94 L95 F98 K99 V102 E106 Q9Y5X3 DPSLQIDIPDALSERDKVKFTVHTKTTLSTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAPTKPDFDGPREKMQKLFAKMKQELEAEYLAVFKKTVSTHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRR 5wy2 C 1.90 BS01 III D 1 I35 P36 D37 A38 L39 S40 E41 M106 K125 E129 Y132 L133 F136 K137 V140 E144 I8 P9 D10 A11 L12 S13 E14 M79 K98 E102 Y105 L106 F109 K110 V113 E117 Q9Y5X3 DPSLQIDIPDALSERDKVKFTVHTKTTLSTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSTHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRR 5wy8 B 3.07 BS01 ZN B 1 E208 H309 E182 H283 Q9NZN1 29081732 SADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLL 5x11 A 2.65 BS01 NUC I 1 K-2 Y20 H38 S39 Y42 Q61 K67 K68 K95 K1 Y23 H41 S42 Y45 Q64 K70 K71 K98 E0TW95 KDPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMI 5x11 A 2.65 BS02 NUC J 1 P0 R2 W34 K37 S39 Q40 Q61 G62 T63 K64 L65 P3 R5 W37 K40 S42 Q43 Q64 G65 T66 K67 L68 E0TW95 KDPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMI 5x11 B 2.65 BS01 NUC I 1 M1 R2 W34 K37 S39 Q40 Q61 T63 K64 L65 M3 R4 W36 K39 S41 Q42 Q63 T65 K66 L67 E0TW95 DPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMID 5x11 B 2.65 BS02 NUC J 1 Y20 H38 S39 Y42 Q61 K67 K68 K95 Y22 H40 S41 Y44 Q63 K69 K70 K97 E0TW95 DPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMID 5x11 E 2.65 BS01 NUC M 1 Y20 H38 S39 Y42 K67 K68 K95 Y22 H40 S41 Y44 K69 K70 K97 E0TW95 DPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASAEPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMI 5x11 E 2.65 BS02 NUC N 1 P0 M1 R2 W34 K37 S39 Q40 G62 T63 K64 L65 P2 M3 R4 W36 K39 S41 Q42 G64 T65 K66 L67 E0TW95 DPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASAEPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMI 5x11 F 2.65 BS02 NUC N 1 Y20 H38 S39 Y42 Q61 L65 K67 K68 K95 Y21 H39 S40 Y43 Q62 L66 K68 K69 K96 E0TW95 PMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRTTIQGTKLEKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMAPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMID 5x13 A 1.70 BS01 HC4 A 1 E29 Q32 F33 L131 S134 H154 L158 A161 R164 E33 Q36 F37 L126 S129 H149 L153 A156 R159 E0TW95 AKDPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASAEPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMIDED 5x14 A 1.68 BS01 FER A 1 E29 Q32 F33 L131 S134 H154 V157 L158 A161 R164 E33 Q36 F37 L126 S129 H149 V152 L153 A156 R159 E0TW95 AKDPMRVLKYAILGLLRKGELSGYDITSYFKEELGQFWSAKHSQIYPELKKLTDEGFITFRKKMYTLTDSGKQELHDWLIRHQPIPETVKDEFMLKAYFISSLSRQEASDLFTDQLLKRKAKLSDLQGSYEKLMASAEPMSFSSPDFGHYLVLTKALEREKNYVSWLESILAMIDED 5x9w A 3.30 BS01 ANP A 1 H588 F589 T590 P608 N609 M610 G611 G612 K613 S614 T615 D686 E687 H753 H584 F585 T586 P604 N605 M606 G607 G608 K609 S610 T611 D672 E673 H739 Q5F5J4 QSMSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTADKLNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEAVTALESQYEPLQCHLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAETLKAAVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRISTFMVEMSETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKAAQKH 5x9w B 3.30 BS01 ANP B 1 V586 F589 T590 N609 G611 G612 K613 S614 T615 D686 E687 H753 V582 F585 T586 N605 G607 G608 K609 S610 T611 D672 E673 H739 Q5F5J4 QSMSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTADKLNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEAVTALESQYEPLQCHLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAETLKAAVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRISTFMVEMSETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKAAQKH 5xlz A 2.30 BS01 GTP A 1 G10 Q11 A12 Q15 I16 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 S178 T179 E183 N206 Y224 L227 N228 I231 G10 Q11 A12 Q15 I16 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 S178 T179 E183 N206 Y224 L227 N228 I231 P81947 29102632 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 5xlz B 2.30 BS02 89U B 1 C239 L240 L246 D249 L253 N256 M257 T312 V313 A314 A315 N348 K350 A352 C238 L239 L245 D248 L252 N255 M256 T311 V312 A313 A314 N347 K349 A351 Q6B856 29102632 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5xlz D 2.30 BS01 GTP D 1 G10 Q11 C12 Q15 A97 G98 N99 S138 G141 G142 T143 G144 V169 V175 S176 E181 N204 L207 Y222 L225 N226 V229 G10 Q11 C12 Q15 A97 G98 N99 S138 G141 G142 T143 G144 V169 V175 S176 E181 N204 L207 Y222 L225 N226 V229 Q6B856 29102632 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xlz D 2.30 BS02 89U D 1 C239 L240 L246 N247 D249 L253 N256 M257 V313 A315 I316 N348 K350 T351 A352 C239 L240 L246 N247 D249 L253 N256 M257 V303 A305 I306 N338 K340 T341 A342 Q6B856 29102632 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5xlz F 2.30 BS01 ACP F 1 K74 I148 Q183 K184 Y185 L186 K198 R202 R222 H239 T241 N242 D318 I330 E331 N333 K74 I126 Q150 K151 Y152 L153 K165 R169 R189 H206 T208 N209 D281 I293 E294 N296 E1BQ43 29102632 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIALISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLATSIFIKLHH 5y02 A 1.80 BS01 MXN A 1 H8 V10 Y30 F77 A83 F86 A87 F91 H6 V8 Y28 F75 A81 F84 A85 F89 A0A1L7NZN4 PEIVRHIVFNRYKSQLSQKQIDQIIADYGNLQNIAPEMKEWKWGTDLGPAVEDRADGFTHAYESTFHSVADFLNFFYSPPALEFAKEFFPACEKIVVLNYIINE 5y02 C 1.80 BS01 MXN C 1 H8 V10 Y30 F77 A83 A87 F91 V99 H9 V11 Y31 F78 A84 A88 F92 V100 A0A1L7NZN4 GNPPEIVRHIVFNRYKSQLSQKQIDQIIADYGNLQNIAPEMKEWKWGTDLGPAVEDRADGFTHAYESTFHSVADFLNFFYSPPALEFAKEFFPACEKIVVLNYIINE 5y02 I 1.80 BS01 HBX I 1 Y30 F77 A83 F86 A87 F90 F91 Y29 F76 A82 F85 A86 F89 F90 A0A1L7NZN4 PPEIVRHIVFNRYKSQLSQKQIDQIIADYGNLQNIAPEMKEWKWGTDLGPAVEDRADGFTHAYESTFHSVADFLNFFYSPPALEFAKEFFPACEKIVVLNYIINE 5y02 K 1.80 BS01 MXN K 1 H8 V10 Y30 F77 F78 A83 F86 A87 H5 V7 Y27 F74 F75 A80 F83 A84 A0A1L7NZN4 EIVRHIVFNRYKSQLSQKQIDQIIADYGNLQNIAPEMKEWKWGTDLGPAVEDRADGFTHAYESTFHSVADFLNFFYSPPALEFAKEFFPACEKIVVLNYIINE 5y02 L 1.80 BS01 HBX L 1 H8 V10 Y30 F78 A83 A87 F91 H6 V8 Y28 F76 A81 A85 F89 A0A1L7NZN4 PEIVRHIVFNRYKSQLSQKQIDQIIADYGNLQNIAPEMKEWKWGTDLGPAVEDRADGFTHAYESTFHSVADFLNFFYSPPALEFAKEFFPACEKIVVLNYIINE 5yk4 A 2.97 BS01 ADP A 1 H588 F589 T590 P608 N609 M610 G611 G612 K613 S614 T615 H753 H584 F585 T586 P604 N605 M606 G607 G608 K609 S610 T611 H739 Q5F5J4 GSMSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTADKLNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEAVTALESQYEPLQCHLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAETLKAAVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRISTFMVEMSETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKAAQKH 5yk4 B 2.97 BS01 ADP B 1 H588 F589 T590 N609 G612 K613 S614 T615 H753 H585 F586 T587 N606 G609 K610 S611 T612 H735 Q5F5J4 SAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTADKLNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEAVTALESQYEPLQCHLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAETLKAAVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRVEMSETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKAAQKH 5yow A 2.10 BS01 FUC A 1 K59 E173 K56 E170 J3SPZ8 29070692 QCDELVHAESKSITCKSEKECSVTGRALLPAVNPGQEACLHFSMPGSPDSKCLKIKVKSINLRCKQASSYYVPEAKARCTSVRRCRWAGDCQSGCPTYFSSNSFSDDWANRMDRAGLGMSGCSDGCGGAACGCFNAAPSCIFWRKWVENPSNRVWKVSPCASWVLAAIIELTLPSGEVKTLEPVTGQATQMFKGVAITYLGSSIEIVGMTRLCEMKEMGTGIMALAPCNDPGHAIMGNVGEIQCSSIESAKHIRSDGCIWNADLVGIELRVDDAVCFSKLTSVEAVANFSKIPAIISGVRFDQGSRIYGSPLDITKVSGEFSVSFRGMRLKLSEISASCTGEITNVSGCYSCMTGASVSIKLHSSKNTTGHLKCDSDETAFSVMEGTHTYRPHMSFDKAVVDEECVLNCGGHSSKLLLKGSLVFM 5yrr A 2.88 BS01 COA A 1 G10 T11 H19 G73 L75 R89 R92 N107 I128 S130 T131 R134 G10 T11 H19 G73 L75 R89 R92 N107 I128 S130 T131 R134 2.7.7.3 A0A059ZFC5 MSKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKNPLFSLEERVALAQSSLGHLSNVEFVGFDGLLVNFFKEQKATAVLRGLRAVSDFEYEFQLANMNRQLDPHFEAVFLTPSEQYSFISSTLIREIARLKGDVTKFVPQAVVEAFERKHQQGW 6aob A 1.70 BS01 MN A 1 D457 D501 D16 D60 A0A060H1D7 29118188 MTEAKEYESVTVFFSDITNFTVISSRTSTKDMMATLNKLWLEYDAIAKRWGVYKVETIGDAYLGVTGAPDVVPDHAERACNFAVDIIEMIKSFKTITGESINIRIGLNSGPVTAGVLGDLNPHWCLVGDTVNTASRMESTSKAGHIHISESTYHFIKSKFVTQPLDVMKMQTYWVLGRKM 6axj A 2.38 BS01 III E 1 H39 H41 H67 T69 Y70 G88 W89 G90 E91 F92 H118 P119 H34 H36 H62 T64 Y65 G83 W84 G85 E86 F87 H113 P114 P53930 GSRIKTLSVSRPIIYGNTAKKMGSVKPPNAPAEHTHLWTIFVRGPQNEDISYFIKKVVFKLHDTYPNPVRSIEAPPFELTETGWGEFDINIKVYFVEEANEKVLNFYHRLRLHPYAAEVSSVYFDEIVFNEPNEEFFKILMSR 6axk A 2.10 BS01 III E 1 N31 Y32 G33 I50 W52 Y52A F58 A95 A96 Y97 T100 S100A N30 Y31 G32 I49 W51 Y52 F58 A98 A99 Y100 T103 S104 VQLVESGGGVVPPGRSLRLSCATSGFTFSNYGMHWVRQAPGKGLEWVAIIWYDGSRNFYAASVEGRFTISRDNSKNTLYLQMNSLRVEDTAVYYCARAAYYDTSGYGDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 6axk B 2.10 BS01 III E 1 Y31 Y91 G95B S95C Y32 Y92 G98 S99 SVLTQPPSVSGAPGQTVTISCTGGSSNIGAGYDVHWYQQLPGTAPKLLIYGNINRPSGVPDRFSGSKSGTSASLAITGLQAEDEADYYCQSYDRRLSGSWVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLVSDFYPGAVTVAWKADGSPVKVGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCRVTHEGSTVEKTVAPA 6axl D 2.40 BS01 III I 1 T31 Y32 Y52A H53 G96 Y97 D101 T31 Y32 Y53 H54 G100 Y101 D107 QMQLVESGGGVVQPGRSLRLSCTASGFTFSTYAMHWVRQSPGQGLQWVAVISYHSTNKYYEDSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDGYSSSFFDFWGQGTLVTVSSASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6axl A 2.40 BS01 III G 1 T31 Y32 Y52A G96 Y97 D101 T31 Y32 Y53 G100 Y101 D107 QMQLVESGGGVVQPGRSLRLSCTASGFTFSTYAMHWVRQSPGQGLQWVAVISYHSTNKYYEDSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDGYSSSFFDFWGQGTLVTVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6ay4 A 2.70 BS01 HEM A 1 L103 A293 G294 T297 T301 P357 L358 I361 R363 P422 F423 G424 H428 C430 I431 L69 A259 G260 T263 T267 P323 L324 I327 R329 P388 F389 G390 H394 C396 I397 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRKQ 6ay4 A 2.70 BS02 TPF A 1 Y107 M110 F114 Y120 A289 F292 A293 L358 C430 Y73 M76 F80 Y86 A255 F258 A259 L324 C396 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRKQ 6ay6 A 2.40 BS01 VOR A 1 Y107 F114 Y120 A289 F292 A293 T297 L358 Y73 F80 Y86 A255 F258 A259 T263 L324 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRK 6ay6 A 2.40 BS02 HEM A 1 Y107 Y120 A293 G294 T297 S298 L358 I361 R363 P422 F423 G424 H428 K429 C430 I431 G432 F435 A436 Y73 Y86 A259 G260 T263 S264 L324 I327 R329 P387 F388 G389 H393 K394 C395 I396 G397 F400 A401 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRK 6ayb A 1.87 BS01 HEM A 1 L103 Y107 Y120 V132 A293 G294 T297 T301 P357 L358 I361 R363 P422 F423 G424 H428 C430 I431 G432 F435 A436 L69 Y73 Y86 V98 A259 G260 T263 T267 P323 L324 I327 R329 P386 F387 G388 H392 C394 I395 G396 F399 A400 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPREEQYIIPKGNILVVSPSVAGRTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRK 6ayb A 1.87 BS03 KKK A 1 F53 Y107 F109 F114 Y120 P213 F217 A289 F292 A293 T297 L358 I359 M360 L467 F19 Y73 F75 F80 Y86 P179 F183 A255 F258 A259 T263 L324 I325 M326 L431 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPREEQYIIPKGNILVVSPSVAGRTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRK 6ayc A 2.60 BS02 1YN A 1 F50 F53 A54 Y107 F109 M110 F114 Y120 P213 F216 F217 A289 G290 F292 A293 T297 L358 M360 M362 Y464 L467 F16 F19 A20 Y73 F75 M76 F80 Y86 P179 F182 F183 A255 G256 F258 A259 T263 L324 M326 M328 Y430 L433 KLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRK 6b3q A 3.70 BS01 III a 1 A198 I310 N312 Y314 V360 N376 A152 I264 N266 Y268 V314 N330 3.4.24.56 P14735 IKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6b3q A 3.70 BS02 III a 2 H112 F115 S137 S138 N139 A140 F141 Y150 K192 A198 W199 F202 H332 G335 G339 V360 G361 Q363 R431 Y609 Q680 M683 F820 Y831 I832 F834 H66 F69 S91 S92 N93 A94 F95 Y104 K146 A152 W153 F156 H286 G289 G293 V314 G315 Q317 R385 Y563 Q634 M637 F774 Y785 I786 F788 3.4.24.56 P14735 IKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMSQAPALPQPEVIQNMTEFKRGLPLFPLVKPH 6b3q B 3.70 BS01 III b 1 H112 F115 S138 N139 A140 F141 T142 S143 Y150 E189 W199 F202 V360 G362 I374 Y609 R824 Y831 H66 F69 S92 N93 A94 F95 T96 S97 Y104 E143 W153 F156 V314 G316 I328 Y563 R778 Y785 3.4.24.56 P14735 IKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFLEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLSPLFDESAKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVVVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQELKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKANLNFEFFSPFAYVDPLHSNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNSGIEIYYQTDMQSTSENMFLELFAQIISEPAFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAESAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREEVIQNMTEFKRGLPLFPLVKPH 6b4n A 1.30 BS01 G53 A 1 D25 G27 A28 D29 D30 K45 I47 G48 G49 P81 V82 I84 D25 G27 A28 D29 D30 K45 I47 G48 G49 P81 V82 I84 Q6QK01 29110408 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF 6b8s A 2.25 BS01 FMN A 1 A66 A67 G68 K71 T91 L105 N116 N145 N178 K214 T242 N243 T244 S261 G262 L265 V289 G290 G291 I311 Y312 S313 A65 A66 G67 K70 T90 L104 N115 N144 N177 K201 T229 N230 T231 S248 G249 L252 V276 G277 G278 I298 Y299 S300 1.3.5.2 B5Z6I2 LYPLVKKYLFSLDAEDAHEKVCKILRTLSKSSFLCSLIHSQWGYKNPKLENEILGLNFPNPLGLAAGFDKNASMLRALIAFGFGYLEAGTLTNEAQVGNERPRLFRHIEEESLQNAMGFNNYGAVLGARSFNRFAPYKTPIGINLGKNKHIEQAHALEDYKAVLNQCLNIGDYYTFNLNKAFVNELFCMAKEMTHKPLFLKIAPDLEIDDMLEIVNSAIEAGAHGIIATNTTIDKSLVFAPKEMGGLSGKCLTKKSREVFKELAKAFFNKSVLVSVGGISDAKEAYERIKMGASLLQIYSAFIYNGPNLCQNILKDLVKLLQKDGFLSVKEAIGA 6b8s B 2.25 BS01 FMN B 1 A66 A67 G68 T91 N116 M118 N145 N178 K214 T242 N243 S261 G262 L265 V289 G290 G291 Y312 S313 A65 A66 G67 T90 N115 M117 N144 N177 K202 T230 N231 S249 G250 L253 V277 G278 G279 Y300 S301 1.3.5.2 B5Z6I2 LYPLVKKYLFSLDAEDAHEKVCKILRTLSKSSFLCSLIHSQWGYKNPKLENEILGLNFPNPLGLAAGFDKNASMLRALIAFGFGYLEAGTLTNEAQVGNERPRLFRHIEEESLQNAMGFNNYGAVLGARSFNRFAPYKTPIGINLGKNKHIEQAHALEDYKAVLNQCLNIGDYYTFNLQNKAFVNELFCMAKEMTHKPLFLKIAPDLEIDDMLEIVNSAIEAGAHGIIATNTTIDKSLVFAPKEMGGLSGKCLTKKSREVFKELAKAFFNKSVLVSVGGISDAKEAYERIKMGASLLQIYSAFIYNGPNLCQNILKDLVKLLQKDGFLSVKEAIGA 6b8u A 2.68 BS01 8EN A 1 I463 V471 A481 K483 E501 L505 L514 I527 T529 W531 C532 I572 H574 F583 G593 D594 F595 I15 V23 A33 K35 E53 L57 L66 I79 T81 W83 C84 I124 H126 F135 G145 D146 F147 2.7.11.1 P15056 29107542 DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLAGSILWMAPEVIRMNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS 6b8u B 2.68 BS01 8EN B 1 I463 V471 A481 K483 E501 V504 L505 L514 I527 T529 W531 C532 L567 I572 H574 F583 G593 D594 F595 I17 V25 A35 K37 E51 V54 L55 L64 I77 T79 W81 C82 L117 I122 H124 F133 G143 D144 F145 2.7.11.1 P15056 29107542 SDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGSILWMAPEVIRMNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS 6b96 A 1.88 BS02 CZV A 1 H656 T768 L770 T805 D808 L809 I826 Y827 F830 Q859 F862 H83 T195 L197 T232 D235 L236 I253 Y254 F257 Q286 F289 3.1.4.17 O00408 29113762 SLYKKAGFYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6b97 A 1.76 BS02 CZY A 1 T768 L770 T805 D808 L809 Q812 Y827 F830 F862 T195 L197 T232 D235 L236 Q239 Y254 F257 F289 3.1.4.17 O00408 29113762 SLYKKAGFYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6b97 B 1.76 BS02 CZY B 1 T768 L770 T805 D808 L809 Q812 I826 Y827 F830 F862 T200 L202 T237 D240 L241 Q244 I258 Y259 F262 F294 3.1.4.17 O00408 29113762 LSTSLYKKAGFDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6b98 A 1.97 BS02 D07 A 1 L809 Q812 I822 I826 Y827 F830 Q859 F862 L237 Q240 I250 I254 Y255 F258 Q287 F290 3.1.4.17 O00408 29113762 TSLYKKAGFYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 6bhh A 1.85 BS01 III B 1 F296 D299 G300 Y301 A302 F332 E357 E386 W387 I388 Y389 S392 T393 R394 F104 D107 G108 Y109 A110 F140 E165 E194 W195 I196 Y197 S200 T201 R202 2.1.1.43 Q15047 GELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEAEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMK 6bjc A 3.30 BS01 III T 1 Y262 R264 W346 D431 E434 V435 Y253 R255 W337 D422 E425 V426 Q2XVP4 29120325 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6bjc A 3.30 BS02 III T 2 R123 A126 D127 C129 T130 D160 R114 A117 D118 C120 T121 D151 Q2XVP4 29120325 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6bjc A 3.30 BS03 III P 1 N293 A333 T334 T337 N284 A324 T325 T328 Q2XVP4 29120325 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6bjc A 3.30 BS04 GTP A 1 Q11 A12 Q15 A99 N101 S140 G143 G144 T145 G146 I171 T179 E183 N206 Y224 L227 N228 Q11 A12 Q15 A90 N92 S131 G134 G135 T136 G137 I162 T170 E174 N197 Y215 L218 N219 Q2XVP4 29120325 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6bjc B 3.30 BS01 III T 1 F399 R400 R401 T419 N426 F389 R390 R391 T409 N416 P02554 29120325 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 6bjc B 3.30 BS02 III P 1 D211 F214 R215 K299 D306 D209 F212 R213 K297 D304 P02554 29120325 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 6bjc B 3.30 BS03 G2P B 1 G10 Q11 C12 Q15 A99 N101 G143 G144 T145 G146 N206 Y224 N228 G10 Q11 C12 Q15 A97 N99 G141 G142 T143 G144 N204 Y222 N226 P02554 29120325 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 6bjc D 3.30 BS01 III P 3 F399 R400 R401 T419 E422 N426 F389 R390 R391 T409 E412 N416 P02554 29120325 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQD 6bjc J 3.30 BS01 GTP J 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 T179 E183 N206 Y224 L227 N228 G10 Q11 A12 Q15 D89 A90 N92 S131 G134 G135 T136 G137 I162 T170 E174 N197 Y215 L218 N219 Q2XVP4 29120325 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDS 6blb A 1.88 BS01 ADP A 1 R25 P26 Y32 I33 G66 L67 G68 K69 T70 T71 Y185 I193 P221 R222 R3 P4 Y10 I11 G44 L45 G46 K47 T48 T49 Y158 I166 P194 R195 3.6.4.12 Q51426 AIRPLKLADYIGQPSVREQMELFIHAARGRQEALDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAALLTNLEAGDVLFVDEIHRLSPIVEEVLYPAMEDFQLDIMIARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNVEDLATIVSRSAGILGLEIEPQGAAEIAKRARGTPRIANRLLRRVRDFAEVRGQGDITRVIADKALNLLDVDERGFDHLDRRLLLTMIDKFDGGPVGIDNLAAALSEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPKRLG 6blk C 1.55 BS01 ATP C 1 N375 A376 K378 W379 D404 P407 I409 F422 R423 S424 A427 G432 G434 L435 G436 L437 T465 N57 A58 K60 W61 D86 P89 I91 F104 R105 S106 A109 G114 G116 L117 G118 L119 T147 3.1.3.- K5BDW2 GAMVVHEPVDMTEVIDRSLERVRRRRSDIEFEVTVTPWQVIGDSSGLGRAVLNVLDNAAKWSPPGGRVGVRLYQIDPGHAELVITDQGPGIPPQERHLVFERFFRSASARSMPGSGLGLAIVKQVVLKHGGALRVDYADPAAQPPGTAIHIVLPGRPM 6blk A 1.55 BS01 ATP A 1 N375 A376 K378 W379 D404 I409 V417 F422 R423 S424 G432 S433 G434 L435 G436 L437 T465 N53 A54 K56 W57 D82 I87 V95 F100 R101 S102 G105 S106 G107 L108 G109 L110 T138 3.1.3.- K5BDW2 VHEPVDMTEVIDRSLERVRRRRSDIEFEVTVTPWQVIGDSSGLGRAVLNVLDNAAKWSPPGGRVGVRLYQIDPGHAELVITDQGPGIPPQERHLVFERFFRSMPGSGLGLAIVKQVVLKHGGALRVDYADPAAQPPGTAIHIVLPGRPM 6bll B 3.40 BS01 NUC E 1 G45 K46 R47 M48 R49 K50 R112 N152 F153 I156 G3 K4 R5 M6 R7 K8 R70 N110 F111 I114 Q9C0J8 FDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNL 6bll C 3.40 BS01 NUC E 1 C68 K69 H70 R73 C76 K77 K78 F84 P94 E95 Y97 F98 S106 N107 F112 C69 K70 H71 R74 C77 K78 K79 F85 P95 E96 Y98 F99 S107 N108 F113 O95639 GMQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHID 6bll C 3.40 BS02 ZN C 1 C41 C49 C55 H59 C42 C50 C56 H60 O95639 GMQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHID 6ei3 A 2.10 BS01 78M A 1 Y91 T92 I95 W96 L99 W202 Y76 T77 I80 W81 L84 W187 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS02 78M A 2 T383 F499 A502 L503 G506 T368 F484 A487 L488 G491 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS03 78M A 3 S184 W185 I192 L193 I196 S169 W170 I177 L178 I181 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS04 78M A 4 A412 W413 A397 W398 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS05 78M A 5 F388 V391 A395 A398 A402 E407 M409 W413 L416 F373 V376 A380 A383 A387 E392 M394 W398 L401 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS06 78M A 6 E61 I65 F69 I71 F75 R115 F119 L122 L267 C268 E46 I50 F54 I56 F60 R100 F104 L107 L252 C253 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS07 78M A 7 E259 Q260 G262 L263 V264 L267 E244 Q245 G247 L248 V249 L252 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS08 78M A 8 L173 L176 H180 W340 L158 L161 H165 W325 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS09 78M A 9 W374 L379 R380 T383 S384 A387 A509 R510 W359 L364 R365 T368 S369 A372 A494 R495 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS10 78M A 10 L168 P338 F341 M346 A348 L349 L352 I411 L153 P323 F326 M331 A333 L334 L337 I396 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS11 78M A 11 L173 H180 I189 L158 H165 I174 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS12 78M A 12 L172 W340 L157 W325 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS13 78M A 13 L352 M355 P359 L363 L337 M340 P344 L348 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS14 78M A 14 V272 A276 W283 R306 V309 A312 P316 W462 Y508 V257 A261 W268 R291 V294 A297 P301 W447 Y493 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS15 78M A 15 A398 F492 A383 F477 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ 6ei3 A 2.10 BS16 78M A 16 F119 G123 F127 F104 G108 F112 PRQIPFIIGNEACERFSFYGMRNILVQFLITSLLLQEVGAPERDAEAKHILHSFMIGVFFFPLLGGWLADRFFGKYTTIIWFSLIYCAGHACLALFEDSRSGFFVGLGLIAFGAGGIKPLVASFMVDQFDQSNKHRAKVVFDAFYWIINFGSLFASLLIPLALKHLGPSWAFGIPGILMFIATAVFWLGRKRYVRVPLPPKDPHGFGAVVRSALLAHAPGQGRPGLALAAISVLLALACLGLTEQLGLVICLCMALVLLLAGIGGGTWWQLERARGTHPDAAVDGVRALLRVLVIFALVTPFFSLFDQKASTWVLQGREMRMPAWFTASQMQALNPLLVMLLIPFNNLVLYPLLRRLGWEPTSLRRMTSGIAFSGVAWIAVGAIQVAMDGGEPMHIAWQILPYALLTFGEVLVSATGIEFAYSQAPPSMKGVVMSFWYLTTTVGNLWVLLSNVAVRNATVTSHIADTGLSEAAFLMFFFAAFAFLAALAFGLYARRYRMVDNYRPANLYFQ