5gym A 2.60 BS01 WY5 A 1 R84 W87 L215 L218 R39 W42 L168 L171 P19793 PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLALHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 5gym B 2.60 BS01 WY5 G 1 W87 L215 W43 L171 P19793 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 5gym C 2.60 BS01 WY5 C 1 R84 W87 L215 R40 W43 L171 P19793 DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLKLIGDTPIDTFLMEMLEAP 5gym E 2.60 BS01 WY5 C 1 V47 I50 K222 I229 V1 I4 K174 I181 P19793 VTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 5gym F 2.60 BS01 WY5 D 1 V47 I229 V4 I184 P19793 NDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 5gym G 2.60 BS01 WY5 G 1 V47 I50 L218 K222 I229 V4 I7 L172 K176 I183 P19793 NDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 5gym H 2.60 BS01 WY5 A 1 L218 K222 L172 K176 P19793 PNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 5h2q A 1.66 BS01 ZN A 1 H673 H709 D710 D823 H86 H122 D123 D236 3.1.4.- Q38F42 AITNREREAVLRIEFPNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMARHSEFLEKYLELMKTSYNVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRTKSNRAQWERVL 5h2q A 1.66 BS02 LLI A 1 M785 I824 N826 W837 A838 V841 T842 F845 M862 G874 Q875 F878 M198 I237 N239 W250 A251 V254 T255 F258 M275 G287 Q288 F291 3.1.4.- Q38F42 AITNREREAVLRIEFPNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMARHSEFLEKYLELMKTSYNVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRTKSNRAQWERVL 5h2r A 1.80 BS02 LLN A 1 M785 D823 I824 N826 V827 S834 W837 A838 V841 T842 F845 M862 L871 G874 Q875 F878 V882 M198 D236 I237 N239 V240 S247 W250 A251 V254 T255 F258 M275 L284 G287 Q288 F291 V295 3.1.4.- Q38F42 AITNREREAVLRIEFPNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMARHSEFLEKYLELMKTSYNVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRTKSNRAQWERVL 5h2r B 1.80 BS02 LLN B 1 Y668 M785 I824 N826 V827 W837 A838 V841 T842 F845 M862 G874 Q875 F878 Y82 M199 I235 N237 V238 W248 A249 V252 T253 F256 M273 G285 Q286 F289 3.1.4.- Q38F42 TAITNREREAVLRIEFPNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMARHSEFLEKYLELMKTVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRTKSNRAQWERVLE 5h4j A 1.80 BS01 FKM A 1 V65 A98 G99 V100 I101 Y105 N108 V109 G110 V112 V42 A75 G76 V77 I78 Y82 N85 V86 G87 V89 3.6.1.23 P33316 MQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALD 5ixz B 2.40 BS01 HEM B 1 M1 Y2 W74 T78 Y83 L87 F97 L101 L104 H105 V108 L115 R116 P118 F120 Y134 S136 R138 L141 M144 L148 M1 Y2 W74 T78 Y83 L87 F97 L101 L104 H105 V108 L115 R116 P118 F120 Y134 S136 R138 L141 M144 L148 Q8YUQ7 MYGLVNKAIQDMISKHHGEDTWEAIKQKAGLEDIDFFVGMEAYSDDVTYHLVGAASEVLGKPAEELLIAFGEYWVTYTSEEGYGELLASAGDSLPEFMENLDNLHARVGLSFPQLRPPAFECQHTSSKSMELHYQSTRAGLAPMVLGLLHGLGKRFQTKVEVTQTAFRETGEDHDIFSIKYE 5m4a A 2.90 BS01 TRE A 1 F303 Y307 W309 D310 N346 Y352 R355 Q357 E424 R473 G476 D478 W624 F706 W708 F124 Y128 W130 D131 N167 Y173 R176 Q178 E245 R294 G297 D299 W437 F503 W505 3.2.1.28 P32356 NPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRIRQWDYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSSLRPQERNLYGL 5mi4 A 1.80 BS01 7NQ A 1 Y137 D243 R347 C550 Y134 D240 R344 C547 3.2.1.169,3.2.1.52 Q89ZI2 SLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSKKGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILPSAAEELESFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPCQPGVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMISNVIKNLPLQVKANRVLISPVVKWAAGNSVEIELDAIYPGENIQINFLEISTDGKEWKTVDLKQKESRLSAGLQKAPVKFVRFTNLRQFVLTIEKK 5mi5 A 2.15 BS01 OAN A 1 G135 F136 Y137 K166 D242 D243 Y282 W286 V314 N339 D344 N372 G132 F133 Y134 K163 D239 D240 Y279 W283 V311 N336 D341 N369 3.2.1.169,3.2.1.52 Q89ZI2 SLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSKKGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILPSAAEELESFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPCQPGVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMKNLPLQVKANRVLISPAGNSEIELDAIYPGENIQINFLEISTDGKEWKTVDLKQKSRLSAGLQKAPVKFVRFTVSDRQFVLTIEK 5mi5 A 2.15 BS02 7NQ A 1 Y137 D344 P549 C550 Y134 D341 P546 C547 3.2.1.169,3.2.1.52 Q89ZI2 SLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSKKGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILPSAAEELESFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPCQPGVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMKNLPLQVKANRVLISPAGNSEIELDAIYPGENIQINFLEISTDGKEWKTVDLKQKSRLSAGLQKAPVKFVRFTVSDRQFVLTIEK 5mi6 A 2.00 BS02 7NQ A 1 Y137 D344 Y345 R347 C550 Y134 D341 Y342 R344 C547 3.2.1.169,3.2.1.52 Q89ZI2 SLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSKKGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILPSAAEELESFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPCQPGVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMISNVKNLPLQVKANRVLISPANEVVKWAAGNSVEIELDAIYPGENIQINFEISTDGKEWKTVDLKQKERLSAGLQKAPVKFVRFTNVSQFVLTIEK 5mi7 A 2.10 BS02 7NT A 1 Y137 D344 R347 P549 C550 Y134 D341 R344 P546 C547 3.2.1.169,3.2.1.52 Q89ZI2 SLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSKKGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILPSAAEELESFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPCQPGVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMIKNLPLQVKANRVLISPEIELDAIYPGENIQINFEISTDGKEWKTVDLKQKESRLSAGLQKAPVKFVRFTNQFVLTIEK 5mu3 A 2.10 BS01 III C 1 L186 I187 K189 K200 K207 L80 I81 K83 K94 K101 Q6CVQ9 29046335 ATDFVQWENSVRLIGVSLFPVNYDNIEFMGIRLELFDELSLKYDPPFYVILKPSVKRLGIWELFKHNLPKYINIHQHWQLITKDTDTSDSNIMKFANLCYKDLLKVHSRVQFFRKLEGNYVNDKQYSLLHIDNMGLNVSFRLGADIIKIKVDDGDDEIIDCTFNGEKNISLLGSIYGITNRFQS 5mu3 B 2.10 BS01 III C 1 R190 L194 H195 M198 Y235 P236 E237 T238 L239 I240 L241 Q246 K247 D250 F251 I253 Y254 Q255 Y256 G257 I258 R84 L88 H89 M92 Y129 P130 E131 T132 L133 I134 L135 Q140 K141 D144 F145 I147 Y148 Q149 Y150 G151 I152 Q6CRN7 29046335 NIEQRKKYLDITLNDVTVTCEKDMILLRKGSFTASFRIAVENESIRSMAIDLNAFEVELQPIIQYAEDTQNVNVAMMAVVQFLRIKELHEQMISKIVEASKFIRASNNTITLNDLEVSFHCYWNLPSPYPETLILTNKVQKILDFLIYQYGIQLGVIKYGSTI 5mu3 D 2.10 BS01 III F 1 L186 I187 K189 K200 L204 K207 L80 I81 K83 K94 L98 K101 Q6CVQ9 29046335 ATDFVQWENSVRLIGVSLFPVNYDNIEFMGIRLELFDELSLKYDPPFYVILKPSVKRLGIWELFKHNLPKYINIHQHWQLITKDTDTSDSNIMKFANLCYKDLLKVHSRVQFFRKLEGNYVNDKQYSLLHIDNMGLNVSFRLGADIIKIKVDDGDDEIIDCTFNGEKNISLLGSIYGITNRFQSI 5mu3 E 2.10 BS01 III F 1 R190 I191 L194 H195 M198 Y228 Y235 P236 E237 T238 L239 I240 L241 Q246 K247 D250 F251 I253 Y254 Q255 Y256 G257 I258 R85 I86 L89 H90 M93 Y123 Y130 P131 E132 T133 L134 I135 L136 Q141 K142 D145 F146 I148 Y149 Q150 Y151 G152 I153 Q6CRN7 29046335 MNIEQRKKYLDITLNDVTVTCEKDMILLRKGSFTASFRIAVENESIRSMAIDLNAFEVELQPIIQYAEDTQNVNVAMMAVVQFLRIKELHEQMISKIVEASKFIRASNNTITLNDLEVSFHCYWNLPSPYPETLILTNKVQKILDFLIYQYGIQLGVIKYGSTI 5n4b A 1.44 BS01 III D 1 K83 F84 S85 T88 L90 F98 S107 K149 F150 S151 S406 A408 R410 T419 S421 G427 Y494 Y496 A503 D504 F506 F507 E601 K714 K78 F79 S80 T83 L85 F93 S102 K144 F145 S146 S401 A403 R405 T414 S416 G422 Y489 Y491 A498 D499 F501 F502 E596 K709 H2E7Q8 WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSHLGGDYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPARERHEGTRSDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGAANGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGHGMGKPTDKNVKDAADKWGFIARALGLELK 5n4e A 2.90 BS01 III C 1 F202 S203 T204 I261 Y262 F278 D280 T281 S282 Y496 F499 T501 A576 S577 N578 A618 W619 R663 F197 S198 T199 I248 Y249 F265 D267 T268 S269 Y483 F486 T488 A563 S564 N565 A605 W606 R650 H2E7Q8 WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSHLGGDYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPASDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGASNGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGAGMGKPTDKNVKDAADKWGFIARALGLELK 5n4e A 2.90 BS02 III C 2 R79 K83 F84 S85 T88 L90 F98 S107 C148 K149 F150 S151 S406 A408 R410 T419 S421 G427 Y494 A503 D504 F506 S508 I511 V524 E601 N707 K714 W715 R74 K78 F79 S80 T83 L85 F93 S102 C143 K144 F145 S146 S393 A395 R397 T406 S408 G414 Y481 A490 D491 F493 S495 I498 V511 E588 N694 K701 W702 H2E7Q8 WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSHLGGDYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPASDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGASNGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGAGMGKPTDKNVKDAADKWGFIARALGLELK 5n4e B 2.90 BS01 III D 1 F202 S203 T204 I261 Y262 F278 D280 T281 S282 K283 Y496 F499 T501 A576 S577 N578 A618 W619 R663 V664 F192 S193 T194 I243 Y244 F260 D262 T263 S264 K265 Y478 F481 T483 A558 S559 N560 A600 W601 R645 V646 H2E7Q8 WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPARDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGASNGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGAGKPTDKNVKDAADKWGFIARALGLELK 5n4e B 2.90 BS02 III D 2 R79 K83 F84 S85 T88 L90 F98 S107 K149 F150 S151 S406 A408 R410 T419 S421 G427 Y494 G495 Y496 T501 S502 A503 S508 I510 I511 V524 E601 N707 K714 W715 R74 K78 F79 S80 T83 L85 F93 S102 K144 F145 S146 S388 A390 R392 T401 S403 G409 Y476 G477 Y478 T483 S484 A485 S490 I492 I493 V506 E583 N687 K694 W695 H2E7Q8 WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPARDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGASNGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGAGKPTDKNVKDAADKWGFIARALGLELK 5n5j A 1.80 BS06 8NT A 1 G179 I180 L181 H218 E219 V235 F237 P238 T239 Y240 K241 G74 I75 L76 H113 E114 V130 F132 P133 T134 Y135 K136 3.4.24.65 P39900 29048889 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5n5k A 1.80 BS06 8NW A 1 G179 I180 L181 L214 T215 H218 E219 V235 F237 P238 T239 Y240 K241 G72 I73 L74 L107 T108 H111 E112 V128 F130 P131 T132 Y133 K134 3.4.24.65 P39900 29048889 VWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5n5n B 4.00 BS01 G2P B 1 Q11 C12 Q15 N101 G143 T145 G146 D179 N206 Y224 N228 Q11 C12 Q15 N99 G141 T143 G144 D177 N204 Y222 N226 P07437 29021343 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 5n5n K 4.00 BS01 GTP K 1 G10 Q11 A12 Q15 A100 N101 S140 G143 G144 T145 G146 T179 E183 N206 Y224 N228 G10 Q11 A12 Q15 A91 N92 S131 G134 G135 T136 G137 T170 E174 N197 Y215 N219 P68363 29021343 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 5n6n C 2.29 BS01 CA C 1 D114 D116 N118 Q120 D125 D72 D74 N76 Q78 D83 3.2.1.28 P32356 DPFSNAEVYYGNRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDVDKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISISRPIRQWDYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSSLRPQERNLYGL 5ndf A 2.30 BS03 LU2 A 1 I253 L270 W282 F361 K363 I179 L196 W208 F287 K289 2.4.1.41 Q10471 29061849 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5ndf B 2.30 BS03 LU2 B 1 I253 V255 A266 L270 W282 F361 K363 I179 V181 A192 L196 W208 F287 K289 2.4.1.41 Q10471 29061849 KVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNL 5ngy A 3.70 BS01 CA A 1 E627 D633 N681 V682 D1182 E457 D463 N511 V512 D1012 VPETITGGRYSLKDGYYVYLDKQGKQVVGPKNIDNHLQYFDETTGKQVKGDFRSVNGKRIYFNANLGYADDYTTDVAGKLVGYDSNGNQVKAGYVTNSQGKTYYFNNQGEAIIGLKTDNNKTQYFGPDGAQVKGAFQQVNGKNIYFDAQTGYARQNVGFLDGTAKGFDEQGNQIKSGIATDLSGNVYYFDASGKMLTGVQNIDGKKYYFDEQGHRRRNYAGVFNNEFIYFGLDGVGQSAIEYQFEKGLTSQNSVATSHNAAKSYDTKSFTNVDGFLTANSWYRPTDILRNGTKWEPSTETDFRPLLMTWWPDKEVQANYLNYMSALGLGDQKIYTGASSQLDLNNAALIVQEAIEKKISLEKSTKWLDDSIKSFIKSKRKDIQGNLVDTNPGWTIDSETGSTNHLQNGAFIFTNSPLVPEANAAEGNRLINRTPSQQTGNHISYASQPYSGDDWGYELLLGNDVDNSNPIVQAEQLNWIHYLMNFGTITAPQDPDAHLANFDSIRIDAVDNVDADLLQIAGDYFKAAYQVGENDKNANQHIHILQDWSPNDVWYNQQVNGNSQLTMDATMQNQLLASLTRPITSRDSMKSFTKDALLVHRTADNSYNQAVPNYSFIRAHDSEVQTIIAKIISDKHPDLYPTVDKALLAKDSALYDEAFTEYNADMQKISSQKQYTHNNMPSAYAILLTNKDTVPRVYYGDLFTDNGEYMANKTPYYDAITSLLTARTKFVSGGQSLSVDKNDVLTSVRYGKGALSATDNGSSDTRNQGIGVIVSNNPNLDLNNDKVTLSMGISHAHQAYRPLLLTNSQGIVAYATDSEVPQNLYKTTNDKGELTFDASEIKGYDTVQTSGYLAVWVPVGASDEQDARTIASTEKNNGNSVYHSNAALDSQLIYEGFSNFQTVPSKNASADEYANVIIAKHAADFNKWGVTSFQMAPQYRSSTDGSFLDAVDTVQNGYAFTDRYDLGFNAADGSKNPTKYGTDEDLRNAIKSLHAQKTYDGSSIQVMADFVPDQLYNMPLEQAVSVIRTDKYGVNSENPDIQNIIYAANIKSSGTDYQSIYGGKYLAELQKNPLFKSLFDRIQISTKKTIDPNTRITQWSAKYFNGSNIQGKGINYVLKDWASNKYFNVSSNDDMYSRLPKQLMNQESNTGFIVDDIGVKYYSISGYQAKNTFVEDGNGEWYYFDNDGYMVKSTEESGPLRTVNASSKKYYILPNGVEIRNSFGQDIQGNTYYFDARGEMVTSQYISDDTQNIYYFNNDGTMAKKG 5ngy A 3.70 BS02 GLC A 1 Y180 Q217 K219 L236 Y10 Q47 K49 L66 VPETITGGRYSLKDGYYVYLDKQGKQVVGPKNIDNHLQYFDETTGKQVKGDFRSVNGKRIYFNANLGYADDYTTDVAGKLVGYDSNGNQVKAGYVTNSQGKTYYFNNQGEAIIGLKTDNNKTQYFGPDGAQVKGAFQQVNGKNIYFDAQTGYARQNVGFLDGTAKGFDEQGNQIKSGIATDLSGNVYYFDASGKMLTGVQNIDGKKYYFDEQGHRRRNYAGVFNNEFIYFGLDGVGQSAIEYQFEKGLTSQNSVATSHNAAKSYDTKSFTNVDGFLTANSWYRPTDILRNGTKWEPSTETDFRPLLMTWWPDKEVQANYLNYMSALGLGDQKIYTGASSQLDLNNAALIVQEAIEKKISLEKSTKWLDDSIKSFIKSKRKDIQGNLVDTNPGWTIDSETGSTNHLQNGAFIFTNSPLVPEANAAEGNRLINRTPSQQTGNHISYASQPYSGDDWGYELLLGNDVDNSNPIVQAEQLNWIHYLMNFGTITAPQDPDAHLANFDSIRIDAVDNVDADLLQIAGDYFKAAYQVGENDKNANQHIHILQDWSPNDVWYNQQVNGNSQLTMDATMQNQLLASLTRPITSRDSMKSFTKDALLVHRTADNSYNQAVPNYSFIRAHDSEVQTIIAKIISDKHPDLYPTVDKALLAKDSALYDEAFTEYNADMQKISSQKQYTHNNMPSAYAILLTNKDTVPRVYYGDLFTDNGEYMANKTPYYDAITSLLTARTKFVSGGQSLSVDKNDVLTSVRYGKGALSATDNGSSDTRNQGIGVIVSNNPNLDLNNDKVTLSMGISHAHQAYRPLLLTNSQGIVAYATDSEVPQNLYKTTNDKGELTFDASEIKGYDTVQTSGYLAVWVPVGASDEQDARTIASTEKNNGNSVYHSNAALDSQLIYEGFSNFQTVPSKNASADEYANVIIAKHAADFNKWGVTSFQMAPQYRSSTDGSFLDAVDTVQNGYAFTDRYDLGFNAADGSKNPTKYGTDEDLRNAIKSLHAQKTYDGSSIQVMADFVPDQLYNMPLEQAVSVIRTDKYGVNSENPDIQNIIYAANIKSSGTDYQSIYGGKYLAELQKNPLFKSLFDRIQISTKKTIDPNTRITQWSAKYFNGSNIQGKGINYVLKDWASNKYFNVSSNDDMYSRLPKQLMNQESNTGFIVDDIGVKYYSISGYQAKNTFVEDGNGEWYYFDNDGYMVKSTEESGPLRTVNASSKKYYILPNGVEIRNSFGQDIQGNTYYFDARGEMVTSQYISDDTQNIYYFNNDGTMAKKG 5ngy A 3.70 BS03 GLC A 2 K219 N235 L236 K49 N65 L66 VPETITGGRYSLKDGYYVYLDKQGKQVVGPKNIDNHLQYFDETTGKQVKGDFRSVNGKRIYFNANLGYADDYTTDVAGKLVGYDSNGNQVKAGYVTNSQGKTYYFNNQGEAIIGLKTDNNKTQYFGPDGAQVKGAFQQVNGKNIYFDAQTGYARQNVGFLDGTAKGFDEQGNQIKSGIATDLSGNVYYFDASGKMLTGVQNIDGKKYYFDEQGHRRRNYAGVFNNEFIYFGLDGVGQSAIEYQFEKGLTSQNSVATSHNAAKSYDTKSFTNVDGFLTANSWYRPTDILRNGTKWEPSTETDFRPLLMTWWPDKEVQANYLNYMSALGLGDQKIYTGASSQLDLNNAALIVQEAIEKKISLEKSTKWLDDSIKSFIKSKRKDIQGNLVDTNPGWTIDSETGSTNHLQNGAFIFTNSPLVPEANAAEGNRLINRTPSQQTGNHISYASQPYSGDDWGYELLLGNDVDNSNPIVQAEQLNWIHYLMNFGTITAPQDPDAHLANFDSIRIDAVDNVDADLLQIAGDYFKAAYQVGENDKNANQHIHILQDWSPNDVWYNQQVNGNSQLTMDATMQNQLLASLTRPITSRDSMKSFTKDALLVHRTADNSYNQAVPNYSFIRAHDSEVQTIIAKIISDKHPDLYPTVDKALLAKDSALYDEAFTEYNADMQKISSQKQYTHNNMPSAYAILLTNKDTVPRVYYGDLFTDNGEYMANKTPYYDAITSLLTARTKFVSGGQSLSVDKNDVLTSVRYGKGALSATDNGSSDTRNQGIGVIVSNNPNLDLNNDKVTLSMGISHAHQAYRPLLLTNSQGIVAYATDSEVPQNLYKTTNDKGELTFDASEIKGYDTVQTSGYLAVWVPVGASDEQDARTIASTEKNNGNSVYHSNAALDSQLIYEGFSNFQTVPSKNASADEYANVIIAKHAADFNKWGVTSFQMAPQYRSSTDGSFLDAVDTVQNGYAFTDRYDLGFNAADGSKNPTKYGTDEDLRNAIKSLHAQKTYDGSSIQVMADFVPDQLYNMPLEQAVSVIRTDKYGVNSENPDIQNIIYAANIKSSGTDYQSIYGGKYLAELQKNPLFKSLFDRIQISTKKTIDPNTRITQWSAKYFNGSNIQGKGINYVLKDWASNKYFNVSSNDDMYSRLPKQLMNQESNTGFIVDDIGVKYYSISGYQAKNTFVEDGNGEWYYFDNDGYMVKSTEESGPLRTVNASSKKYYILPNGVEIRNSFGQDIQGNTYYFDARGEMVTSQYISDDTQNIYYFNNDGTMAKKG 5nh4 A 1.80 BS01 MG A 1 E233 E269 D297 D340 E232 E268 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh4 A 1.80 BS02 GOL A 1 H102 W140 W189 E233 E269 D297 D340 H101 W139 W188 E232 E268 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh4 A 1.80 BS03 GOL B 1 K384 K385 Y388 K383 K384 Y387 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh4 B 1.80 BS02 GOL B 2 H102 W140 W189 E233 E269 H272 D297 D340 H101 W139 W188 E232 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh4 B 1.80 BS03 GOL B 3 Q10 N21 L23 Q9 N20 L22 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh4 B 1.80 BS04 GOL B 4 H26 Y27 D362 A363 R366 H25 Y26 D361 A362 R365 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh5 A 1.80 BS01 CA A 1 E233 E269 H272 D297 D340 E232 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh6 A 1.75 BS02 XYL A 1 W50 H102 W140 W189 E233 K235 E269 H272 D297 D308 D340 W49 H101 W139 W188 E232 K234 E268 H271 D296 D307 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 A 1.90 BS02 MG A 2 E269 H272 D308 D310 E268 H271 D307 D309 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 A 1.90 BS04 XYP A 1 E56 G64 T65 K66 S67 E55 G63 T64 K65 S66 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 A 1.90 BS05 XYS A 1 D41 Y98 K137 D40 Y97 K136 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 A 1.90 BS06 XYS A 2 P22 E351 P21 E350 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 A 1.90 BS07 XYS D 1 D289 A290 D288 A289 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 B 1.90 BS05 XYS B 1 K204 K207 H258 K202 K205 H256 5.3.1.5 Q9P8C9 29045784 KEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 B 1.90 BS06 XYS B 2 K40 D41 Y98 K137 K38 D39 Y96 K135 5.3.1.5 Q9P8C9 29045784 KEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 B 1.90 BS07 XYS B 3 P22 L23 E351 P20 L21 E349 5.3.1.5 Q9P8C9 29045784 KEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh7 D 1.90 BS04 XYP D 1 E56 G64 K66 S67 E55 G63 K65 S66 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 A 1.86 BS03 XLS A 1 W50 H102 W140 W189 E233 E269 D297 D340 W49 H101 W139 W188 E232 E268 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 A 1.86 BS04 XYP A 1 G64 K66 S67 G63 K65 S66 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 A 1.86 BS06 XYP A 3 Q8 Q10 L23 Q7 Q9 L22 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 A 1.86 BS07 CA A 3 A276 G277 A275 G276 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 B 1.86 BS05 XLS B 1 W50 H102 W140 W189 E233 E269 H272 D297 D340 W49 H101 W139 W188 E232 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 B 1.86 BS06 XYP B 2 G64 T65 K66 S67 G63 T64 K65 S66 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh8 C 1.86 BS03 XLS C 1 W50 H102 W189 E233 E269 D297 D340 W49 H101 W188 E232 E268 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh9 A 2.08 BS03 XLS A 1 W50 H102 W189 E233 K235 E269 H272 D297 D340 W49 H101 W188 E232 K234 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh9 B 2.08 BS04 XYP B 1 D41 P97 Y98 K137 D40 P96 Y97 K136 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh9 C 2.08 BS05 MN C 2 E269 H272 D308 D310 D340 E268 H271 D307 D309 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh9 D 2.08 BS01 XYP B 3 K204 H258 K203 H257 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nh9 D 2.08 BS06 XYP D 2 K40 D41 R44 Y98 K137 K39 D40 R43 Y97 K136 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nha C 1.80 BS02 MN C 2 E269 H272 N299 D308 D310 E268 H271 N298 D307 D309 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nha D 1.80 BS03 SOR D 1 W50 H102 W189 E233 E269 H272 D297 D340 W49 H101 W188 E232 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhb D 2.40 BS02 FE2 D 2 K235 E269 H272 D308 D310 D340 K233 E267 H270 D306 D308 D338 5.3.1.5 Q9P8C9 29045784 KEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhc A 1.93 BS04 HYP A 1 K265 G291 M292 L293 G329 G331 V333 K264 G290 M291 L292 G328 G330 V332 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhc C 1.93 BS04 HYP C 1 K265 G291 M292 L293 G329 G331 F332 V333 K263 G289 M290 L291 G327 G329 F330 V331 5.3.1.5 Q9P8C9 29045784 KEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhd B 1.80 BS05 XYP B 2 D41 R44 Y98 K137 D40 R43 Y97 K136 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhd B 1.80 BS07 XYS B 1 V288 D289 R328 V287 D288 R327 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhd C 1.80 BS03 XYP C 1 K40 D41 R44 P97 Y98 K137 K38 D39 R42 P95 Y96 K135 5.3.1.5 Q9P8C9 29045784 KEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhe A 1.86 BS05 XYP A 3 Q8 I9 Q10 L23 Q7 I8 Q9 L22 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhe C 1.86 BS01 XYS C 1 H102 W140 F146 W189 E233 E269 H272 D297 D340 H101 W139 F145 W188 E232 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nhe D 1.86 BS02 XYS D 2 W50 H102 F146 W189 E233 E269 H272 D297 D340 W49 H101 F145 W188 E232 E268 H271 D296 D339 5.3.1.5 Q9P8C9 29045784 AKEYFPQIQKIKFEGKDSKNPLAFHYYDAEKEVMGKKMKDWLRFAMAWWHTLCAEGADQFGGGTKSFPWNEGTDAIEIAKQKVDAGFEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNLKAVVAYLKEKQKETGIKLLWSTANVFGHKRYMNGASTNPDFDVVARAIVQIKNAIDAGIELGAENYVFWGGREGYMSLLNTDQKREKEHMATMLTMARDYARSKGFKGTFLIEPKPMEPTKHQYDVDTETAIGFLKAHNLDKDFKVNIEVNHATLAGHTFEHELACAVDAGMLGSIDANRGDYQNGWDTDQFPIDQYELVQAWMEIIRGGGFVTGGTNFDAKTRRNSTDLEDIIIAHVSGMDAMARALENAAKLLQESPYTKMKKERYASFDSGIGKDFEDGKLTLEQVYEYGKKNGEPKQTSGKQELYEAIVAMYQ 5nkw A 1.48 BS02 BGC A 1 N28 H66 N67 N28 H66 N67 A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nkw A 1.48 BS06 BGC A 5 P53 V54 N55 D58 N173 P53 V54 N55 D58 N173 A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nln A 1.90 BS03 XYP A 2 S77 H147 E148 S77 H147 E148 A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nlp A 1.59 BS05 XYS A 1 Q14 Y21 K50 S51 V52 P53 Q14 Y21 K50 S51 V52 P53 1.-.-.- A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nlp A 1.59 BS06 XYP A 4 V12 D13 Q14 V12 D13 Q14 1.-.-.- A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nlq A 1.50 BS03 XYP A 2 K32 E148 I158 Q162 K32 E148 I158 Q162 1.-.-.- A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nlq A 1.50 BS06 XYP A 5 Y153 P157 Y153 P157 1.-.-.- A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nlr A 2.00 BS05 BGC A 4 H147 E148 R159 Y203 H147 E148 R159 Y203 1.-.-.- A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nls A 1.75 BS06 BGC A 5 D150 R159 Y203 D150 R159 Y203 1.-.-.- A0A0S2GKZ1 29057953 HTLVWGVWVNGVDQGDGRNIYIRSPPNNNPVKNLTSPDMTCNVDNRVVPKSVPVNAGDTLTFEWYHNTRDDDIIASSHHGPIAVYIAPAASNGQGNVWVKLFEDAYNVTNSTWAVDRLITAHGQHSVVVPHVAPGDYLFRAEIIALHEADSLYSQNPIRGAQFYISCAQITINSSDDSTPLPAGVPFPGAYTDSTPGIQFNIYTTPATSYVAPPPSVWSGALGGSIAQVGDASLE 5nlt A 1.90 BS01 CU A 1 H79 Y169 H78 Y168 1.-.-.- 29057953 TRMFSVWVNGVDQGDGQNVYIRTPPNTDPIKDLASPALACNVKGGEPVPQFVSASAGDKLTFEWYRVKRGDDIIDPSHSGPITTWIAAFTSPTMDGTGPVWSKIHEEGYDASTKSWAVDKLIANKGMWDFTLPSQLKPGKYMLRQEIVAHHESDATFDKNPKRGAQFYPSCVQVDVKGVGGDAVPDQAFDFNKGYKYSDPGIAFDMYTDFDSYPIPGPPVWDA 5nq7 A 2.75 BS04 CU A 4 H416 C472 I474 H477 F482 H395 C451 I453 H456 F461 1.10.3.2 D7F485 29055703 AIGPVADLTLTNAAVSPDGFTREAVVVNGITPAPLIAGKKGDRFQLNVIDNLTNHTMLKTTSIHWHGFFQHGTNWADGVSFVNQCPIASGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPQASLYDIDNDDTVITLADWYHLAAKVGQRFPLGADATLINGLGRTPGTTSADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTIIEADSVNTQPLEVDSIQIFAAQRYSFVLDASQPVDNYWIRANPPFGNVGFAGGINSAILRYDGAPEVEPTTTQTTPTKPLNEADLHPLTPMPVPGRPEPGGVDKPLNMVFNFNGTNFFINNHSFVPPSVPVLLQILSGAQAAQDLVPEGSVYVLPSNASIEISFPATANAPGSPHPFHLHGHTFAVVRSAGSSEYNYDNPVFRDVVSTGTPGDNVTIRFQTNNPGPWFLHCHIDFHLDAGFAVVMAEDTPDTASVNQVPQSWSDLCPIYDALDPSDL 5nq8 A 2.00 BS03 CU A 3 H87 W128 H130 H473 H66 W107 H109 H452 Q96TR6 29055703 AIGPVADLTLTNAAVSPDGFSREAVVVNGVTPAPLISGQKGDRFQLNVIDNLTNHTMLKTTSIHWHGFFQHGTNWADGPAFVNQCPIASGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPQASLYDIDNDDTVITLADWYHVAAKLGPRFPPGSDATLINGLGRSPGTTAADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTIIEADSVNTQPLEVDSIQIFAAQRYSFVLDASQPVDNYWIRANPSFGNTGFAGGINSAILRYLGAPEIEPTTTQTTPTKPLTEVDLHPLTPMAVPGRPEPGGVDKPLNMVFNFNGTNFFINNHSFVPPSVPVLLQILSGAQAAQDLVPEGSVYVLPSNSSIEISFPATVNAPGAPHPFHLHGHTFAVVRSAGSSEYNYDNPIFRDVVSTGTPGDNVTIRFQTANPGPWFLHCHIDFHLDAGFAVVMAEDTPDTTAANPVPQAWSDLCPIYDALDPSDL 5o11 A 2.40 BS01 3NG A 1 L44 G45 S46 V52 A65 K67 L120 E121 R122 L174 I185 D186 L11 G12 S13 V17 A30 K32 L85 E86 R87 L139 I150 D151 2.7.11.1 P11309 29042609 LESQYQVGPLLGSGGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5o12 A 2.40 BS01 1RO A 1 L44 S46 S51 V52 A65 K67 H68 L120 E121 R122 V126 L174 I185 D186 L11 S13 S14 V15 A28 K30 H31 L81 E82 R83 V87 L135 I146 D147 2.7.11.1 P11309 29042609 LESQYQVGPLLGSSVYSGIRVSDNLPVAIKHVEKDRISDWGELPTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5o13 A 2.44 BS01 9G5 A 1 L44 F49 V52 A65 K67 I104 L120 R122 V126 D131 L174 I185 L11 F16 V19 A32 K34 I71 L87 R89 V93 D98 L141 I152 2.7.11.1 P11309 29042609 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5o5k A 3.40 BS01 ONM A 1 D256 I257 V258 G259 F260 T261 P269 S298 G299 D300 R344 D47 I48 V49 G50 F51 T52 P60 S89 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k A 3.40 BS02 MN A 1 D256 I257 D300 D47 I48 D91 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k A 3.40 BS03 MN A 2 D256 D300 D47 D91 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k A 3.40 BS04 ONM B 1 F254 K296 M303 V366 W367 G368 D369 V371 N372 S375 F45 K87 M94 V157 W158 G159 D160 V162 N163 S166 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k B 3.40 BS01 ONM A 1 M303 D365 V366 W367 G368 D369 N372 R376 K411 M94 D156 V157 W158 G159 D160 N163 R167 K202 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k B 3.40 BS02 ONM B 1 D256 I257 G259 F260 T261 P269 L272 G299 D300 R344 D47 I48 G50 F51 T52 P60 L63 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k C 3.40 BS01 ONM D 1 M303 D365 V366 W367 G368 V371 N372 R376 K411 M94 D156 V157 W158 G159 V162 N163 R167 K202 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k E 3.40 BS01 ONM E 1 D256 I257 F260 T261 P269 L272 V273 G299 D300 R344 D47 I48 F51 T52 P60 L63 V64 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k E 3.40 BS03 MN E 2 D256 D300 S301 D47 D91 S92 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k E 3.40 BS04 ONM F 1 K296 V366 W367 G368 V371 N372 K87 V157 W158 G159 V162 N163 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k F 3.40 BS01 ONM E 1 M303 D365 V366 W367 G368 N372 R376 K411 M94 D156 V157 W158 G159 N163 R167 K202 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k F 3.40 BS02 ONM F 1 D256 I257 V258 G259 F260 T261 A264 P269 L272 G299 D300 R344 D47 I48 V49 G50 F51 T52 A55 P60 L63 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k F 3.40 BS03 MN F 1 D256 I257 D300 R344 D47 I48 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k J 3.40 BS01 ONM I 1 F254 M303 D365 V366 G368 D369 V371 N372 R376 K411 F45 M94 D156 V157 G159 D160 V162 N163 R167 K202 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k J 3.40 BS02 ONM J 1 D256 I257 V258 G259 F260 T261 A264 G299 D300 R344 D47 I48 V49 G50 F51 T52 A55 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k J 3.40 BS03 MN J 1 D256 I257 V258 G259 D300 R344 D47 I48 V49 G50 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k H 3.40 BS01 MN H 1 D256 I257 F260 D300 D47 I48 F51 D91 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k H 3.40 BS02 ONM H 1 D256 I257 V258 G259 F260 T261 E262 A264 P269 D300 R344 D47 I48 V49 G50 F51 T52 E53 A55 P60 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k H 3.40 BS03 ONM G 1 F254 K296 M303 D365 W367 N372 R376 K411 F45 K87 M94 D156 W158 N163 R167 K202 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k G 3.40 BS01 ONM H 1 F254 K296 W367 G368 D369 V371 N372 S375 F45 K87 W158 G159 D160 V162 N163 S166 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k G 3.40 BS02 ONM G 1 D256 I257 F260 T261 A264 P269 L272 S298 G299 D300 R344 D47 I48 F51 T52 A55 P60 L63 S89 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5k K 3.40 BS01 ONM K 1 G259 F260 T261 E262 P269 L272 S298 G299 D300 R344 G50 F51 T52 E53 P60 L63 S89 G90 D91 R135 4.6.1.1 X8CHM4 AVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRK 5o5l A 2.70 BS02 MN A 1 D256 I257 F260 D300 R344 D52 I53 F56 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l A 2.70 BS03 MN A 2 D256 S298 D300 S301 D52 S94 D96 S97 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l A 2.70 BS04 ONM B 1 F254 K296 V366 W367 G368 V371 N372 F50 K92 V162 W163 G164 V167 N168 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l B 2.70 BS01 ONM A 1 K296 M303 D365 V366 W367 G368 D369 V371 N372 R376 K411 K92 M99 D161 V162 W163 G164 D165 V167 N168 R172 K207 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l C 2.70 BS04 ONM D 1 D365 V366 W367 G368 D369 V371 N372 R376 K411 D161 V162 W163 G164 D165 V167 N168 R172 K207 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l D 2.70 BS01 ONM C 1 F254 K296 V366 W367 G368 V371 N372 S375 F50 K92 V162 W163 G164 V167 N168 S171 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l D 2.70 BS02 ONM D 1 D256 I257 G259 F260 T261 P269 L272 V273 S298 G299 D300 R344 D52 I53 G55 F56 T57 P65 L68 V69 S94 G95 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l F 2.70 BS02 ONM F 1 D256 I257 G259 F260 T261 P269 G299 D300 R344 D52 I53 G55 F56 T57 P65 G95 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l G 2.70 BS03 ONM G 1 I257 G259 F260 T261 P269 L272 G299 D300 R344 I53 G55 F56 T57 P65 L68 G95 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l G 2.70 BS04 ONM H 1 K296 D365 V366 W367 G368 V371 N372 R376 K411 K92 D161 V162 W163 G164 V167 N168 R172 K207 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l H 2.70 BS01 ONM G 1 F254 K296 V366 W367 G368 D369 V371 N372 F50 K92 V162 W163 G164 D165 V167 N168 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l H 2.70 BS02 ONM H 1 D256 F260 T261 E262 A264 P269 S298 G299 D300 R344 D52 F56 T57 E58 A60 P65 S94 G95 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l I 2.70 BS02 MN I 2 D256 S298 D52 S94 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l I 2.70 BS03 ONM I 1 D256 I257 F260 T261 P269 G299 D300 R344 D52 I53 F56 T57 P65 G95 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l I 2.70 BS04 ONM J 1 D365 V366 G368 V371 N372 R376 K411 D161 V162 G164 V167 N168 R172 K207 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l J 2.70 BS01 ONM I 1 F254 K296 V366 W367 G368 D369 V371 N372 S375 F50 K92 V162 W163 G164 D165 V167 N168 S171 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l J 2.70 BS02 ONM J 1 F260 T261 A264 P269 L272 D300 F56 T57 A60 P65 L68 D96 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l K 2.70 BS01 ONM K 1 D256 I257 F260 T261 E262 P269 L272 V273 S298 G299 D300 R344 D52 I53 F56 T57 E58 P65 L68 V69 S94 G95 D96 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o5l K 2.70 BS02 MN K 1 D256 I257 R344 D52 I53 R140 4.6.1.1 X8CHM4 TQRAEAVMEAEYERSEALLANMLPGSIAERLKSSSRSVIADKYDEVSVLFADIVGFTERASTTTPADLVRFLNRLYGAFDELVDKHGLEKIKVSGDSYMVVSGVPRARPDHAFALADFALDMANVAAALKDPHGDPVPLRMGMACGPVVAGVVGSRRFFYDVWGDAVNVASRMESTDSVGRIQVPEAMYERLKNEFVLQERGRIEVKGKGVMRTWYLIGRKADE 5o6t A 1.57 BS01 ZN A 1 C450 C453 C471 C474 C17 C20 C38 C41 2.3.2.27 P98170 29053960 EISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 5o6t A 1.57 BS02 ZN A 2 C465 H467 C481 C484 C32 H34 C48 C51 2.3.2.27 P98170 29053960 EISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 5o76 A 2.47 BS01 III B 1 Y274 R294 S296 R299 Y307 L315 Q316 T317 P319 F336 Y337 Y225 R245 S247 R250 Y258 L266 Q267 T268 P270 F287 Y288 2.3.2.27 P22681 29053960 TVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPF 5o76 C 2.47 BS01 III D 1 Y274 R294 S296 T298 R299 Y307 L315 Q316 T317 I318 P319 E334 F336 Y227 R247 S249 T251 R252 Y260 L268 Q269 T270 I271 P272 E287 F289 2.3.2.27 P22681 29053960 PGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPF 5o76 C 2.47 BS03 ZN C 2 C396 H398 C416 C349 H351 C369 2.3.2.27 P22681 29053960 PGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPF 5o8f A 3.20 BS01 P9N E 1 I242 Q245 V246 W249 P403 I226 Q229 V230 W233 P317 P31644 28991263 MSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKSQPARAAKIDKMSRIVFPILFGTFNLVYWATYL 5o8f A 3.20 BS02 P9N E 2 A308 T309 A292 T293 P31644 28991263 MSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKSQPARAAKIDKMSRIVFPILFGTFNLVYWATYL 5oc1 A 2.30 BS01 ANN A 1 Y92 I357 I391 S393 F397 T413 I500 F501 H502 H546 Y91 I356 I390 S392 F396 T412 I499 F500 H501 H545 1.1.3.7 O94219 29043303 DFDYVVVGAGNAGNVVAARLTEDPDVSVLVLEAGVSDENVLGAEAPLLAPGLVPNSIFDWNYTTTAQAGYNGRSIAYPRGRMLGGSSSVHYMVMMRGSTEDFDRYAAVTGDEGWNWDNIQQFVRKNEMVVPPADNHNTSGEFIPAVHGTNGSVSISLPGFPTPLDDRVLATTQEQSEEFFFNPDMGTGHPLGISWSIASVGNGQRSSSSTAYLRPAQSRPNLSVLINAQVTKLVNSGTTNGLPAFRCVEYAEQEGAPTTTVCAKKEVVLSAGSVGTPILLQLSGIGDENDLSSVGIDTIVNNPSVGRNLSDHLLLPAAFFVNSNQTFDNIFRDSSEFNVDLDQWTNTRTGPLTALIANHLAWLRLPSNSSIFQTFPDPAAGPNSAHWETIFSNQWFHPAIPRPDTGSFMSVTNALISPVARGDIKLATSNPFDKPLINPQYLSTEFDIFTMIQAVKSNLRFLSGQAWADFVIRPFDPRLRDPTDDAAIESYIRDNANTIFHPVGTASMSPRGASWGVVDPDLKVKGVDGLRIVDGSILPFAPNAHTQGPIYLVGERGADLIKADQ 5oc1 A 2.30 BS02 FAD A 1 G9 G11 N12 A13 L32 E33 A34 W61 P79 R80 G81 R82 M83 G86 S87 H91 Y92 M93 V94 A229 Q230 V231 S271 A272 G273 F501 H502 D535 G536 H546 T547 Q548 I551 G8 G10 N11 A12 L31 E32 A33 W60 P78 R79 G80 R81 M82 G85 S86 H90 Y91 M92 V93 A228 Q229 V230 S270 A271 G272 F500 H501 D534 G535 H545 T546 Q547 I550 1.1.3.7 O94219 29043303 DFDYVVVGAGNAGNVVAARLTEDPDVSVLVLEAGVSDENVLGAEAPLLAPGLVPNSIFDWNYTTTAQAGYNGRSIAYPRGRMLGGSSSVHYMVMMRGSTEDFDRYAAVTGDEGWNWDNIQQFVRKNEMVVPPADNHNTSGEFIPAVHGTNGSVSISLPGFPTPLDDRVLATTQEQSEEFFFNPDMGTGHPLGISWSIASVGNGQRSSSSTAYLRPAQSRPNLSVLINAQVTKLVNSGTTNGLPAFRCVEYAEQEGAPTTTVCAKKEVVLSAGSVGTPILLQLSGIGDENDLSSVGIDTIVNNPSVGRNLSDHLLLPAAFFVNSNQTFDNIFRDSSEFNVDLDQWTNTRTGPLTALIANHLAWLRLPSNSSIFQTFPDPAAGPNSAHWETIFSNQWFHPAIPRPDTGSFMSVTNALISPVARGDIKLATSNPFDKPLINPQYLSTEFDIFTMIQAVKSNLRFLSGQAWADFVIRPFDPRLRDPTDDAAIESYIRDNANTIFHPVGTASMSPRGASWGVVDPDLKVKGVDGLRIVDGSILPFAPNAHTQGPIYLVGERGADLIKADQ 5olw A 2.28 BS01 CA A 1 E124 N127 E124 N127 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQKQKHHH 5olw A 2.28 BS02 CA A 2 D8 D10 E169 D170 S171 D8 D10 E169 D170 S171 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQKQKHHH 5olw A 2.28 BS03 CA A 3 P89 V92 L97 P89 V92 L97 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQKQKHHH 5olx A 1.38 BS03 MGF A 1 D8 K145 D8 K145 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQ 5olx A 1.38 BS04 MGF A 2 D8 D10 D8 D10 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQ 5olx A 1.38 BS05 MGF A 3 D8 L9 D10 S114 D8 L9 D10 S114 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQ 5olx A 1.38 BS06 MGF A 4 D8 A115 K145 D8 A115 K145 5.4.2.6 P71447 MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVIVPDTSHYTLEFLKEVWLQ 5oqd B 2.45 BS01 ZN B 1 C515 C517 H538 C541 C9 C11 H32 C35 Q24459 29058710 RVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNFKKKLLRGDMFFVFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQHQKYHHLLNDIWPFILEQRHQLPICWRTLPETALMERLKQTLKDYSDRFVCGREFKRAPAFYALRHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMPEE 5oqd B 2.45 BS02 ZN B 2 C530 C533 C560 C563 C24 C27 C54 C57 Q24459 29058710 RVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNFKKKLLRGDMFFVFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQHQKYHHLLNDIWPFILEQRHQLPICWRTLPETALMERLKQTLKDYSDRFVCGREFKRAPAFYALRHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMPEE 5orl A 1.69 BS01 ADP A 1 L139 G140 G142 K143 F144 G145 V147 A160 K162 L194 E211 A213 T217 E260 N261 L263 D274 L13 G14 G16 K17 F18 G19 V21 A34 K36 L68 E85 A87 T91 E134 N135 L137 D148 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orl A 1.69 BS03 A4W A 1 E183 I184 H187 L188 Y246 C247 V252 H280 E57 I58 H61 L62 Y120 C121 V126 H154 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orn A 2.19 BS03 A5E A 1 W128 F157 L159 Y197 W2 F31 L33 Y71 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5oro A 2.12 BS03 A5H A 1 W128 F133 E152 F157 Y197 W2 F7 E26 F31 Y71 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orp A 2.19 BS03 A5K A 1 W128 E152 F157 Y197 I209 W2 E26 F31 Y71 I83 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orr A 2.09 BS03 A5Q A 1 K166 E175 L178 R179 Y199 K40 E49 L52 R53 Y73 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5ors A 1.98 BS03 A5W A 1 K166 L178 R179 V182 Y199 K40 L52 R53 V56 Y73 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5ort A 2.56 BS01 ADP A 1 L139 G140 G142 F144 G145 V147 A160 K162 E211 A213 T217 E260 N261 L263 D274 L13 G14 G16 F18 G19 V21 A34 K36 E85 A87 T91 E134 N135 L137 D148 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5ort A 2.56 BS03 A5Z A 1 K166 E175 R179 Y199 H201 V206 K40 E49 R53 Y73 H75 V80 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orv A 1.88 BS03 MG A 2 K162 D274 K36 D148 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orv A 1.88 BS04 A65 A 1 K166 L178 R179 Y199 H201 K40 L52 R53 Y73 H75 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orw A 2.00 BS03 A6E A 1 E175 R179 Y199 H201 V206 E49 R53 Y73 H75 V80 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5orx A 1.88 BS03 A6H A 1 E175 L178 Y199 H201 V206 E49 L52 Y73 H75 V80 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5ory A 1.99 BS03 AY4 A 1 E175 L178 R179 V182 Y199 H201 E49 L52 R53 V56 Y73 H75 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5os0 A 1.74 BS03 A6Z A 1 K166 R179 Y199 H201 K40 R53 Y73 H75 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5os1 A 1.90 BS01 ADP A 1 G140 G142 K143 G145 V147 A160 K162 L194 E211 A213 T217 E260 N261 L263 D274 G14 G16 K17 G19 V21 A34 K36 L68 E85 A87 T91 E134 N135 L137 D148 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5os1 A 1.90 BS03 A7H A 1 K166 E175 L178 R179 V182 Y199 K40 E49 L52 R53 V56 Y73 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5os3 A 1.81 BS03 A7N A 1 K166 L178 R179 Y199 K40 L52 R53 Y73 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5os4 A 1.88 BS03 A8H A 1 K166 E175 R179 V182 Y199 H201 V206 K40 E49 R53 V56 Y73 H75 V80 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5os5 A 1.74 BS03 A8K A 1 E175 L178 R179 V182 E183 Y199 V206 E51 L54 R55 V58 E59 Y75 V82 2.7.11.1 O14965 29045126 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN 5os6 A 2.20 BS03 A7Q A 1 R179 E183 Y199 H201 R53 E57 Y73 H75 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5osd A 1.99 BS03 A9B A 1 W128 F133 E152 F157 L159 Y197 W4 F9 E28 F33 L35 Y73 2.7.11.1 O14965 29045126 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5ose A 1.90 BS03 A98 A 1 W128 F133 E152 F157 L159 R195 Y197 W2 F7 E26 F31 L33 R69 Y71 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5osf A 1.89 BS03 A9E A 1 W128 F133 F157 L159 Y197 W2 F7 F31 L33 Y71 2.7.11.1 O14965 29045126 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPS 5ot2 A 3.20 BS01 NUC T 1 F252 K332 R344 Q447 G835 Y836 R1386 E1403 E1404 F241 K321 R333 Q436 G824 Y825 R1344 E1361 E1362 2.7.7.6 P04050 QQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVREEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ot2 A 3.20 BS02 NUC N 1 K101 W139 K1109 H1387 K98 W136 K1089 H1345 2.7.7.6 P04050 QQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVREEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ot2 A 3.20 BS03 NUC P 1 I250 S251 F252 Q447 D481 D483 D485 I239 S240 F241 Q436 D470 D472 D474 2.7.7.6 P04050 QQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVREEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ot2 A 3.20 BS07 AHW T 1 K830 T831 T834 T1077 K819 T820 T823 T1066 2.7.7.6 P04050 QQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKDEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVREEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM 5ot2 B 3.20 BS01 NUC T 1 T791 M792 R857 R942 G1121 R1122 R1129 G1131 T688 M689 R754 R822 G1001 R1002 R1009 G1011 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVLAINAKTITSGLKYALATGNWGEQAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5ot2 B 3.20 BS02 NUC P 1 Q481 Q776 K979 K987 H1097 R1124 Q393 Q673 K859 K867 H977 R1004 2.7.7.6 P08518 DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVLAINAKTITSGLKYALATGNWGEQAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF 5ot2 L 3.20 BS01 ZN L 1 C31 E33 C34 C48 C51 H53 C5 E7 C8 C22 C25 H27 P40422 LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR 5oy4 A 3.20 BS01 III X 1 Y216 I228 F229 V263 L266 V267 I270 K271 T275 I281 Y288 T289 E290 F291 K292 F293 P294 I296 Y181 I193 F194 V228 L231 V232 I235 K236 T240 I246 Y253 T254 E255 F256 K257 F258 P259 I261 2.7.11.26,2.7.11.1 P49841 29057057 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQ 5oy4 A 3.20 BS02 B4K A 1 A83 K85 E97 M101 L132 D133 Y134 V135 R141 L188 C199 D200 F201 A48 K50 E62 M66 L97 D98 Y99 V100 R106 L153 C164 D165 F166 2.7.11.26,2.7.11.1 P49841 29057057 KVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQ 5oy4 B 3.20 BS02 B4K B 1 I62 A83 K85 E97 M101 V110 L132 D133 Y134 V135 L188 C199 D200 F201 I33 A54 K56 E68 M72 V81 L102 D103 Y104 V105 L158 C169 D170 F171 2.7.11.26,2.7.11.1 P49841 29057057 RDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARI 5pgu A 2.35 BS01 NAP A 1 G41 A42 S43 K44 G45 I46 A65 R66 S67 T92 M93 N119 I121 V168 S169 S170 Y183 K187 L215 G216 L217 I218 T220 T222 A223 G16 A17 S18 K19 G20 I21 A40 R41 S42 T67 M68 N94 I96 V143 S144 S145 Y158 K162 L190 G191 L192 I193 T195 T197 A198 1.1.1.146 P28845 28537398 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMD 5pgu A 2.35 BS02 8K4 A 1 T124 S125 L126 S170 L171 A172 Y177 V180 Y183 L217 T222 A223 V227 M233 T99 S100 L101 S145 L146 A147 Y152 V155 Y158 L192 T197 A198 V202 M208 1.1.1.146 P28845 28537398 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMD 5pgu B 2.35 BS01 NAP B 1 G41 A42 S43 K44 G45 I46 A65 R66 S67 T92 M93 N119 H120 I121 Y147 V168 S169 S170 Y183 K187 L215 G216 L217 I218 T220 T222 A223 G30 A31 S32 K33 G34 I35 A54 R55 S56 T81 M82 N108 H109 I110 Y136 V157 S158 S159 Y172 K176 L204 G205 L206 I207 T209 T211 A212 1.1.1.146 P28845 28537398 SMTGGQQMGRGSNEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSY 5pgu E 2.35 BS02 8K4 E 1 T124 S125 L126 S170 L171 Y177 V180 Y183 L217 A223 V227 M233 T100 S101 L102 S146 L147 Y153 V156 Y159 L193 A199 V203 M209 1.1.1.146 P28845 28537398 EEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMD 5pgv A 2.35 BS02 8K7 A 1 I121 T124 L126 S170 L171 A172 Y177 V180 Y183 L215 G216 L217 A223 A226 V227 I96 T99 L101 S145 L146 A147 Y152 V155 Y158 L190 G191 L192 A198 A201 V202 1.1.1.146 P28845 28537398 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMD 5pgv B 2.35 BS02 8K7 B 1 I121 T124 S170 L171 A172 Y177 V180 Y183 G216 L217 A223 A226 V227 V231 M233 I111 T114 S160 L161 A162 Y167 V170 Y173 G206 L207 A213 A216 V217 V221 M223 1.1.1.146 P28845 28537398 ASMTGGQQMGRGSNEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMDRFI 5pgw A 2.37 BS02 8KA A 1 I121 T124 L126 S170 L171 Y177 P178 M179 V180 Y183 L215 G216 L217 T222 A223 A226 V227 I96 T99 L101 S145 L146 Y152 P153 M154 V155 Y158 L190 G191 L192 T197 A198 A201 V202 1.1.1.146 P28845 28537398 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSY 5pgw B 2.37 BS02 8KA B 1 I121 T124 L126 S170 L171 Y177 P178 M179 V180 Y183 L215 G216 L217 A223 A226 V227 V231 M233 I111 T114 L116 S160 L161 Y167 P168 M169 V170 Y173 L205 G206 L207 A213 A216 V217 V221 M223 1.1.1.146 P28845 28537398 ASMTGGQQMGRGSNEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNM 5pgx A 2.50 BS02 8KD A 1 T124 L126 S170 L171 A172 Y177 V180 Y183 L215 G216 L217 A223 A226 M233 T99 L101 S145 L146 A147 Y152 V155 Y158 L190 G191 L192 A198 A201 M208 1.1.1.146 P28845 28537398 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMD 5pgy E 2.07 BS01 NAP E 1 G41 A42 S43 K44 G45 I46 A65 R66 S67 T92 M93 E94 N119 H120 I121 V168 S169 S170 Y183 K187 L215 G216 L217 I218 T220 T222 A223 G17 A18 S19 K20 G21 I22 A41 R42 S43 T68 M69 E70 N95 H96 I97 V144 S145 S146 Y159 K163 L191 G192 L193 I194 T196 T198 A199 1.1.1.146 P28845 28537398 EEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMDR 5pgy E 2.07 BS02 8KG E 1 T124 L126 S170 L171 Y177 V180 Y183 L215 G216 L217 T222 A223 A226 V227 M233 T100 L102 S146 L147 Y153 V156 Y159 L191 G192 L193 T198 A199 A202 V203 M209 1.1.1.146 P28845 28537398 EEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPCRKILEELYSTSYNMDR 5pgz A 2.90 BS01 NAP A 1 G41 A42 S43 K44 G45 I46 A65 R66 S67 G91 T92 M93 N119 H120 I121 I168 S169 S170 Y183 K187 L215 G216 I218 T220 T222 A223 G17 A18 S19 K20 G21 I22 A41 R42 S43 G67 T68 M69 N95 H96 I97 I144 S145 S146 Y159 K163 L191 G192 I194 T196 T198 A199 1.1.1.146 P50172 28537398 EEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSITLCVLGLIDTETAMKEISGIINAQASPKEECALEIIKGTALRKSEVYYDKSPLTPILLGNPGRKIMEFFSLRYYNKDMF 5pgz A 2.90 BS02 8KG A 1 T124 L126 S170 L171 A172 Q177 I180 Y183 G216 L217 A223 E226 I227 I231 T100 L102 S146 L147 A148 Q153 I156 Y159 G192 L193 A199 E202 I203 I207 1.1.1.146 P50172 28537398 EEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSITLCVLGLIDTETAMKEISGIINAQASPKEECALEIIKGTALRKSEVYYDKSPLTPILLGNPGRKIMEFFSLRYYNKDMF 5til A 2.83 BS01 III C 1 M5 Y7 E9 Y45 Y59 E63 K66 Q70 W73 V76 S77 N80 Y84 Q97 S99 F116 Y123 T143 K146 W147 H155 Y156 Y159 E163 W167 Y171 M4 Y6 E8 Y44 Y58 E62 K65 Q69 W72 V75 S76 N79 Y83 Q96 S98 F115 Y122 T142 K145 W146 H154 Y155 Y158 E162 W166 Y170 P01899 PHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEP 5til G 2.83 BS01 III C 1 N38 G102 N32 G96 DQQQVRQSPQSLTVWEGGTTVLTCSYEDSTFNYFPWYQQFPGEGPALLISILSVSDKKEDGRFTTFFNKREKKLSLHIIDSQPGDSATYFCAALYGNEKITFGAGTKLTIKPNI 5til H 2.83 BS01 III C 1 D93 A94 G95 G96 R97 N98 D93 A94 G95 G96 R97 N98 AVTQSPRSKVAVTGGKVTLSCHQTNNHDYMYWYRQDTGHGLRLIHYSYVADSTEKGDIPDGYKASRPSQENFSLILELASLSQTAVYFCASSDAGGRNTLYFGAGTRLSVLEDLRNVTPPKVSLFEPSKAEIANKQKATLVCLARGFFPDHVELSWWVNGKEVHSGVCTDPQAYKESNYSYSLSSRLRVSFWHNPRNHFRCQVQFHGLSEEDKSPKPVTQNISAEAWGRA 5til K 2.83 BS01 III F 1 G102 N103 G100 N101 QQKEKHDQVRQSPQSLTVWEGGTTVLTCSYEDSTFNYFPWYQQFPGEGPALLISILSVSDKKEDGRFTTFFNKREKKLSLHIIDSQPGDSATYFCAALYGNEKITFGAGTKLTIKPNI 5tje E 3.20 BS01 III J 1 Y101 G102 Y97 G98 QQKEKQVRQSPQSLTVWEGGTTVLTCSYEDSTFNYFPWYQQFPGEGPALLISILSVSDKKEDGRFTTFFNKREKKLSLHIIDSQPGDSATYFCAALYGNEKITFGAGTKLTIKPNI 5tje F 3.20 BS01 III J 1 D93 A94 G95 G96 R97 D93 A94 G95 G96 R97 AVTQSPRSKVAVTGGKVTLSCHQTNNHDYMYWYRQDTGHGLRLIHYSYVADSTEKGDIPDGYKASRPSQENFSLILELASLSQTAVYFCASSDAGGRNTLYFGAGTRLSVLEDLRNVTPPKVSLFEPSKAEIANKQKATLVCLARGFFPDHVELSWWVNGKEVHSGVCTDPQAYKESNYSYSLSSRLRVSATFWHNPRNHFRCQVQFHGLSEEDKWPEGSPKPVTQNISAEAWGRAD 5too A 2.03 BS01 ZN A 1 D38 D352 H353 D15 D329 H330 3.1.3.1 Q9KJX5 NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVSAIGHTSIFTGSVPSIHGIAGADWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLADAASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFMKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG 5too A 2.03 BS02 ZN A 2 D305 H309 H486 D282 H286 H458 3.1.3.1 Q9KJX5 NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVSAIGHTSIFTGSVPSIHGIAGADWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLADAASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFMKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG 5tpq A 2.45 BS03 ZN A 3 E134 H162 H452 E127 H155 H445 3.1.3.1 P00634 ENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTASAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQAATPAALVAHVTSSKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVAGASIDAQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKWSHP 5tr4 A 2.20 BS01 61T B 1 V440 G443 A444 D470 M471 D472 R481 Q482 K494 R519 V520 A542 L543 D544 N545 D547 A548 Y551 V427 G430 A431 D457 M458 D459 R468 Q469 K481 R506 V507 A529 L530 D531 N532 D534 A535 Y538 6.2.1.45 P22515 IDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDMDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDRVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVKGVLESISDSLSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTPAHVSTMILEICADDKEGEDVEVPFITIHL 5tr4 C 2.20 BS01 61T D 1 G441 G443 A444 T469 D470 M471 D472 Q482 K494 R519 V520 P522 A542 L543 D544 N545 D547 A548 Y551 G428 G430 A431 T456 D457 M458 D459 Q469 K481 R506 V507 P509 A529 L530 D531 N532 D534 A535 Y538 6.2.1.45 P22515 IDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDMDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDRVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTVSTMILEICADDKEGEDVEVPFITIHL 5tyq A 2.16 BS01 SAH A 1 D107 G131 C132 G133 V136 D152 V153 D179 M180 N194 P196 L207 L208 I214 D106 G130 C131 G132 V135 D151 V152 D178 M179 N193 P195 L206 L207 I213 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEED 5tyq A 2.16 BS02 MG A 1 E98 D206 E97 D205 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEED 5u0n A 2.12 BS03 7XP A 1 D95 V96 E97 E98 Q101 D107 W110 E111 N194 S195 P196 T197 N198 L208 N235 R281 D94 V95 E96 E97 Q100 D106 W109 E110 N193 S194 P195 T196 N197 L207 N234 R280 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEEDP 5u0t A 2.11 BS01 SAH A 1 D107 G131 C132 G133 V136 L137 D152 V153 G178 D179 M180 N194 P196 L207 L208 I214 D106 G130 C131 G132 V135 L136 D151 V152 G177 D178 M179 N193 P195 L206 L207 I213 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEEDPDALL 5u0t A 2.11 BS02 7QM A 1 D95 V96 E98 D107 W110 E111 N194 S195 P196 N198 L208 E209 N235 R281 D94 V95 E97 D106 W109 E110 N193 S194 P195 N197 L207 E208 N234 R280 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEEDPDALL 5u1e A 2.21 BS01 9CS A 1 D95 V96 E98 Q101 W110 E111 N194 S195 N198 L208 E209 N235 R281 D98 V99 E101 Q104 W113 E114 N197 S198 N201 L211 E212 N238 R284 Q2MG72 28876898 GSHMIVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEEDPDALLDGTDRL 5u4t A 2.09 BS01 SAH A 1 D107 G131 C132 G133 D152 V153 N154 A157 D179 M180 N194 P196 L207 L208 I214 D106 G130 C131 G132 D151 V152 N153 A156 D178 M179 N193 P195 L206 L207 I213 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEEDPDALLDGTDR 5u4t A 2.09 BS02 TRS A 1 D107 W110 E111 N194 S195 P196 T197 L208 D106 W109 E110 N193 S194 P195 T196 L207 Q2MG72 28876898 IVGGSTIQPERVDAAALRQLGDAMRKVVGSADPTPLADLLSGTPVDPDELTREVGADGRQALLDSGMAVDDGTTFSSPLRGHQLHGVVVLSDPDVEEEVQHRWYVDPLWEADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALSRLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIVEVNLAMNDYPGDPFRERLADWLGLTENGLRVQIFTSQRRATESGGEWKRGWLVVAPGPVGLTEVEWPYHDRYEEDPDALLDGTDR 5ufi A 2.58 BS01 8B1 A 1 I86 F89 P97 A98 S99 V102 A106 Q114 C115 E116 F117 F164 M177 A180 Y181 L184 I27 F30 P38 A39 S40 V43 A47 Q55 C56 E57 F58 F105 M118 A121 Y122 L125 Q96GG9 LDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 5ufi C 2.58 BS01 8B1 C 1 F89 P97 V102 A106 Q114 C115 E116 F117 F164 M177 A180 Y181 L184 F30 P38 V43 A47 Q55 C56 E57 F58 F105 M118 A121 Y122 L125 Q96GG9 LDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQI 5v5x A 3.50 BS01 CA A 1 E223 D276 E278 D310 E16 D69 E71 D103 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x A 3.50 BS02 CA A 2 E223 E278 D307 E308 D310 D343 E16 E71 D100 E101 D103 D136 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x A 3.50 BS03 CA A 3 N309 N311 D341 D343 N347 D394 N102 N104 D134 D136 N140 D187 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x A 3.50 BS04 CA A 4 E326 D379 E381 D415 N416 E119 D172 E174 D208 N209 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x A 3.50 BS05 CA A 5 E326 E381 D412 V413 D415 D448 E119 E174 D205 V206 D208 D241 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x A 3.50 BS07 CA A 7 E431 N432 D489 E491 D525 E224 N225 D282 E284 D318 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x A 3.50 BS08 CA A 8 E431 E491 D522 R523 D525 D565 E224 E284 D315 R316 D318 D358 Q91XX3 NRPVFSQDVYRVRLPEDLPPGTTVLRLKAMDQDEGINAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5v5x C 3.50 BS05 CA C 5 E326 R380 E381 D412 V413 D415 D448 E109 R163 E164 D195 V196 D198 D231 Q91XX3 PVFSQDVYRVRLPEDLPPGTTVLRLKAAEFTYSFLGVANKAQFSLDPITGDIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIIITSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSNNYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNAPVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPKALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMRVLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDGGQPPLSATATLLLVF 5vcb b 4.10 BS01 PNS d 1 A112 D113 A107 D108 2.7.8.7 P24224 29054754 AILGLGTDIVEIARIEAVIARSGDRLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES 5vcb a 4.10 BS01 PNS d 1 E58 K62 E57 K61 2.7.8.7 P24224 29054754 AILGLGTDIVEIARIEAVIARSGDRLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES 5vcb f 4.10 BS01 PNS f 1 S36 E57 E60 S36 E57 E60 B7MJ81 29054754 STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA 5vcb e 4.10 BS01 PNS e 1 D35 S36 D35 S36 B7MJ81 29054754 STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA 5vcb d 4.10 BS01 PNS d 1 V29 S36 E60 V29 S36 E60 B7MJ81 29054754 STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA 5vcb F 4.10 BS01 PNS F 1 S36 T39 E60 S36 T39 E60 B7MJ81 29054754 STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA 5vcb D 4.10 BS01 PNS D 1 V29 D35 S36 E60 V29 D35 S36 E60 B7MJ81 29054754 STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA 5vcb P 4.10 BS01 PNS P 1 V29 S36 T39 V29 S36 T39 B7MJ81 29054754 STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA 5vcb T 4.10 BS01 PNS V 1 L111 A112 L106 A107 2.7.8.7 P24224 29054754 AILGLGTDIVEIARIEAVIARSGDRLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES 5vcb U 4.10 BS02 PNS W 1 L111 A112 D113 L105 A106 D107 2.7.8.7 P24224 29054754 AILGLGTDIVEIARIEAVIARSGDRLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES 5ve8 A 2.70 BS01 III C 1 D840 S881 F882 G885 E889 N923 Y926 R976 N980 E1016 E1017 D756 S797 F798 G801 E805 N839 Y842 R888 N892 E928 E929 Q6CMF0 29035199 ALPALIHILQNSSNDGIKQLAGVEARKQVSKHAATQTSVKQSLLNSAFNEGKDAVRHANARVIASIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLALHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAKFASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLVKLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALKVASEEIDVEDELTNEDEENTPALTALRLISNASGELSPSQVGVPIIEHLPTMLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLALDGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAAGSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAVKSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFLQTIIPEIFKTLEQEEYQVNTGIAYEKEVAAAALSELAIASKEHFLEYVEPSLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSYVDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMDNGDSTHLDQLCREALSVLKGEHACQTIEDLDASETEATLLDVALDIYVALSTNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENPFIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKSLYEILSVADEKNLAEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIPALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEKESERIELETNSTLGREENLEKRKQFQSEEIKQQVIELLKHLNQQFNGAVAQNPVLAQVIA 5ve8 A 2.70 BS02 III C 2 D465 E469 F470 S505 S509 F512 N556 D416 E420 F421 S456 S460 F463 N507 Q6CMF0 29035199 ALPALIHILQNSSNDGIKQLAGVEARKQVSKHAATQTSVKQSLLNSAFNEGKDAVRHANARVIASIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLALHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAKFASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLVKLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALKVASEEIDVEDELTNEDEENTPALTALRLISNASGELSPSQVGVPIIEHLPTMLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLALDGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAAGSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAVKSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFLQTIIPEIFKTLEQEEYQVNTGIAYEKEVAAAALSELAIASKEHFLEYVEPSLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSYVDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMDNGDSTHLDQLCREALSVLKGEHACQTIEDLDASETEATLLDVALDIYVALSTNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENPFIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKSLYEILSVADEKNLAEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIPALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEKESERIELETNSTLGREENLEKRKQFQSEEIKQQVIELLKHLNQQFNGAVAQNPVLAQVIA 5ve8 B 2.70 BS01 III E 1 D840 F882 G885 E889 N923 Y926 R976 N980 E1016 E1017 D762 F804 G807 E811 N845 Y848 R893 N897 E933 E934 Q6CMF0 29035199 ALPALIHILQNSSNDGIKQLAGVEARKQVSKHWGSLDAATQTSVKQSLLNSAFNEGKDAVRHANARVIASIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLALHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAKFASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLVKLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALKVASEEIDVEDELTNEDEENTPALTALRLISNASGELSPSQVGVPIIEHLPTMLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLALDGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAAGSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAVKSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFLQTIIPEIFKTLEQEEYQFTVNTGIAYEKEVAAAALSELAIASKEHFLEYVEPSLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSYVDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMDNGDSTHLDQLCREALSVLKGEHACQTIDLDASETEATLLDVALDIYVALSTNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENPFIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKSLYEILSVADEKNDEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIPALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEKESERIELETNSTLGREENLEKRKQFQSEEIKQQVIELLKHLNQQFNGAVAQNPVLAQVIA 5ve8 B 2.70 BS02 III E 2 Q430 E469 F470 S505 S509 F512 N556 R590 E593 Y664 Q386 E425 F426 S461 S465 F468 N512 R546 E549 Y596 Q6CMF0 29035199 ALPALIHILQNSSNDGIKQLAGVEARKQVSKHWGSLDAATQTSVKQSLLNSAFNEGKDAVRHANARVIASIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLALHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAKFASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLVKLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALKVASEEIDVEDELTNEDEENTPALTALRLISNASGELSPSQVGVPIIEHLPTMLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLALDGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAAGSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAVKSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFLQTIIPEIFKTLEQEEYQFTVNTGIAYEKEVAAAALSELAIASKEHFLEYVEPSLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSYVDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMDNGDSTHLDQLCREALSVLKGEHACQTIDLDASETEATLLDVALDIYVALSTNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENPFIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKSLYEILSVADEKNDEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIPALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEKESERIELETNSTLGREENLEKRKQFQSEEIKQQVIELLKHLNQQFNGAVAQNPVLAQVIA 5vqi B 2.50 BS01 III A 1 L109 S110 K111 F142 W146 N150 A152 S153 G154 T159 Q185 W188 N192 G195 D196 W231 N235 D270 L28 S29 K30 F61 W65 N69 A71 S72 G73 T78 Q104 W107 N111 G114 D115 W150 N154 D189 Q9C2K9 29054975 DLPKMVEGVFSSEIDKQIQATTKFRKLLSKERNPPIEEVIKTGVVGRFVEFLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPDVREQAVWALGNIAGDSPQCRDYVLSCGALRPLLTLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWNTIAPALPVLAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVTGDDVQTQVIINCGALPCLLSLLSSNKDGIRKEACWTISNITAGNSAQIQSVIDANIIPPLIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIKPLCDLLACPDNKIIQVALDGLENILKVGELDKNAASINRYALFIEECGGMEKIHDCQTNANEEIYMKAYNIIEKYFS 5vqi B 2.50 BS02 III C 1 D280 R315 N319 V321 T322 G323 D325 T328 E354 W357 S360 N361 A364 E396 W399 D199 R234 N238 V240 T241 G242 D244 T247 E273 W276 S279 N280 A283 E315 W318 Q9C2K9 29054975 DLPKMVEGVFSSEIDKQIQATTKFRKLLSKERNPPIEEVIKTGVVGRFVEFLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPDVREQAVWALGNIAGDSPQCRDYVLSCGALRPLLTLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWNTIAPALPVLAKLVYSLDDEVLIDACWAISYLSDGSNDKIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVTGDDVQTQVIINCGALPCLLSLLSSNKDGIRKEACWTISNITAGNSAQIQSVIDANIIPPLIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIKPLCDLLACPDNKIIQVALDGLENILKVGELDKNAASINRYALFIEECGGMEKIHDCQTNANEEIYMKAYNIIEKYFS 5vt0 I 3.78 BS01 NUC R 1 R151 H165 W183 D199 R200 R202 E374 I445 L481 L538 E541 R542 V547 R903 G1261 K1262 R1269 M1273 R149 H163 W181 D197 R198 R200 E372 I443 L479 L536 E539 R540 V545 R901 G1259 K1260 R1267 M1271 2.7.7.6 P0A8V2 28988932 YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 5vt0 J 3.78 BS01 NUC R 1 Y46 R47 T48 K50 R53 L71 K87 C88 L120 K216 R311 K334 R346 R352 A426 T790 A791 Y795 R798 R1148 Q1326 Y31 R32 T33 K35 R38 L56 K72 C73 L105 K201 R296 K319 R331 R337 A411 T775 A776 Y780 R783 R1107 Q1285 2.7.7.6 P0A8T7 28988932 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 5vt0 L 3.78 BS01 NUC R 1 V98 R99 G106 L110 R385 S389 K392 Y394 S428 T429 T432 R436 R441 R451 H455 E515 T552 R554 R562 T572 L573 E574 R584 E585 R586 R588 Q589 K593 R596 K597 H600 V5 R6 G13 L17 R243 S247 K250 Y252 S286 T287 T290 R294 R299 R309 H313 E373 T410 R412 R420 T430 L431 E432 R442 E443 R444 R446 Q447 K451 R454 K455 H458 P00579 28988932 TTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDIDPELAREKFAELRAQYVVTRDTIKHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD 5vxc A 1.87 BS01 COA A 1 Y50 K57 K58 K61 R107 I272 H273 P274 Y11 K18 K19 K22 R68 I233 H234 P235 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSIKEK 5vxc A 1.87 BS02 MG A 1 E171 D206 E132 D167 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSIKEK 5vxo A 2.27 BS01 1VU A 1 Y50 V51 K57 K58 K61 D76 G77 R107 V244 R249 I272 H273 P274 Y11 V12 K18 K19 K22 D37 G38 R68 V205 R210 I233 H234 P235 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSI 5vxo A 2.27 BS02 1VU C 1 A311 M318 D320 A272 M279 D281 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSI 5vxo B 2.27 BS01 1VU A 1 A311 T313 M318 D320 A272 T274 M279 D281 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSI 5vxo B 2.27 BS02 1VU B 1 Y50 K57 K58 K61 D76 G77 R107 V244 I272 H273 P274 Y11 K18 K19 K22 D37 G38 R68 V205 I233 H234 P235 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSI 5vxo C 2.27 BS02 1VU C 1 Y50 V51 K57 K58 K61 G77 R107 V244 I272 H273 P274 Y11 V12 K18 K19 K22 G38 R68 V205 I233 H234 P235 Q8N0X4 HKYIPRRAVLYVPGNDEKKIKKIPSLNVDCAVLDCEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVSSGLAEEDLETLLQSRVLPSSLMLPKVESPEEIQWFADKFSFHLKGRKLEQPMNLIPFVETAMGLLNFKAVCEETLKVGPQVGLFLDAVVFGGEDFRASIGATSSKETLDILYARQKIVVIAKAFGLQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVIHPNQIAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSI 5w0v A 2.82 BS01 III C 1 D465 E469 S505 S509 F512 E555 N556 R590 E593 A600 N601 Y664 V668 D416 E420 S456 S460 F463 E506 N507 R541 E544 A551 N552 Y589 V593 Q6CMF0 29035199 AALPALIHILQNSSNDGIKQLAGVEARKQVSKHWATQTSVKQSLLNSAFNEGKDAVRHANARVIASIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLALHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAKFASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLVKLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALKVASEEIDVEDELTNEEENTPALTALRLISNASGELSPSQVGVPIIEHLPTMLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLALDGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAAGSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAVKSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFLQTIIPEIFKTLEQEEYTVNTGIAYEKEVAAAALSELAIASKEHFLEYVEPSLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSYVDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMDNGDSTHLDQLCREALSVLKGEHACQTILDASETEATLLDVALDIYVALSTNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENPFIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKSLYEILSVADEKNDEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIPALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEKESERIELETNSTLGRKRKQFQSEEIKQQVIELLKHLNQQFNGAVAQNPVLAQVIA 5w0v B 2.82 BS01 III D 1 D465 E469 F470 S505 S509 F512 N556 E593 A600 N601 Y664 D401 E405 F406 S441 S445 F448 N492 E529 A536 N537 Y574 Q6CMF0 29035199 LAGVEARKQVSKHWGSLDAATQTSVKQSLLNSAFNEGKDAVRHANARVIASIGSEELDEKKWPELIPNLLQAACDSNPKIRETAIFIILSLLESFNANLALHIDDFLNLFAQTINDSASLETRSLSAQALSYVSSLIEEEGEINPQYAAKFASLIPSVVQVLDATIREGDTTNTKLIFNCLNDFLLLDSQLTGNTIADLVKLALQIAVNSDVDEDIRVFAVQFVTSALVYRKSKINQAKLGPEITLAALKVASEEIDVEDELTNEEENTPALTALRLISNASGELSPSQVGVPIIEHLPTMLSSSNPFERRSILLAISVLVTGSPDYTLSQFDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQDEVARYHEQYLPLVIDIIDSAKHVVIYKYATLALDGLLEFIAHNDIIKYLDPLMNKLFQMLETQQSPKLRAAIVSAIGSCAFAAGSGFVPYFKTSVQYLQQFIQNVSQIEGLSEDDIELKALTFENISTMGRAVKSAAFAEYAEPLVNAAYEAIKTDSARLRESGYAFIANMAKVYGKDFAPFLQTIIPEIFKTLEQEEYTVNTGIAYEKEVAAAALSELAIASKEHFLEYVEPSLKVLAEQVNESYGLKETALHSMWAIVKAVLLTANLKEGEYPKGVPSGSYVDASALAVIQTVREVSLNNVIEEVETSMVISVFQDLSEMLRLFGPIIIMDNGDSTHLDQLCREALSVLKGEHACQTIEDLDASETEATLLDVALDIYVALSTNLVGGFAQVFTTAKPVILQLCQSKSKNKRSFAVGALSEIALGMRDENPFIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSFDVSAIYSPVLKSLYEILSVADEKNLDEATKEIVDRTFSNVCGCVARMILKHQNLVPLEHTIPALLSHLPFNTAFEEYDPIFKLFLKLFQEQNSTIINEAPKVIAIFATVFEKESERIELETNSTLGREEKRKQFQSEEIKQQVIELLKHLNQQFVAQNPVLAQVI 5wke A 1.69 BS01 CUY A 1 V12 I13 Q14 W40 A47 E67 F70 Y73 I74 E80 V81 F84 F88 I96 G98 L114 G116 A117 F123 F144 L147 I148 Y151 V9 I10 Q11 W37 A44 E64 F67 Y70 I71 E77 V78 F81 F85 I93 G95 L111 G113 A114 F120 F141 L144 I145 Y148 P29016 29054999 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGL 5wke A 1.69 BS02 P50 A 1 F10 F58 V63 L66 E68 I69 V72 Y73 G76 F77 A100 V126 A129 F144 I148 M155 T157 V158 L161 Y169 F7 F55 V60 L63 E65 I66 V69 Y70 G73 F74 A97 V123 A126 F141 I145 M152 T154 V155 L158 Y166 P29016 29054999 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGL 5wkg A 2.06 BS02 D21 A 1 F10 L66 I69 V72 Y73 G76 F77 A100 V126 A129 C131 F144 I148 M155 T157 V158 L161 L162 Y169 F7 L63 I66 V69 Y70 G73 F74 A97 V123 A126 C128 F141 I145 M152 T154 V155 L158 L159 Y166 P29016 29054999 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGLN 5wkg A 2.06 BS03 CUY A 1 V12 Q14 G28 S29 W40 A47 Y73 I74 F77 E80 V81 F84 F88 I96 G98 I99 L114 G116 F123 L124 F144 L147 Y151 I154 V9 Q11 G25 S26 W37 A44 Y70 I71 F74 E77 V78 F81 F85 I93 G95 I96 L111 G113 F120 L121 F141 L144 Y148 I151 P29016 29054999 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGLN 5wki A 2.75 BS01 CUY A 1 V12 I13 Q14 G39 W40 F70 Y73 I74 F77 G98 A100 L114 F144 V7 I8 Q9 G34 W35 F65 Y68 I69 F72 G93 A95 L107 F137 P29016 29054999 GPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYW 5wki A 2.75 BS02 D3D D 1 L66 I69 V72 Y73 G76 F77 V126 I148 G153 I154 M155 T157 V158 L161 Y169 L61 I64 V67 Y68 G71 F72 V119 I141 G146 I147 M148 T150 V151 L154 Y162 P29016 29054999 GPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYW 5wki D 2.75 BS01 D3D D 1 Y32 R91 A93 Y94 Q96 Y30 R89 A91 Y92 Q94 Q6P4G7 29054999 KTTQPPSMDCAEGRAANLPCNHSTISGNEYVYWYRQIHSQGPQYIIHGLKNNETNEMASLIITEDRKSSTLILPHATLRDTAVYYCIVRVAYRQKVTFGTGTKLQVIPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 5wki E 2.75 BS01 D3D D 1 A97 R98 Q100 A96 R97 Q99 29054999 AGVSQSPRYKVAKRGQDVALRCDPISGHVSLFWYQQALGQGPEFLTYFQNEAQLDKSGLPSDRFFAERPEGSVSTLKIQRTQQEDSAVYLCASSLARAQGASNTGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 5wl1 A 1.38 BS01 CUY A 1 V12 I13 Q14 H38 A47 F49 F70 Y73 I74 F77 V81 F84 F88 M90 I96 G98 I99 A100 L114 G116 F123 L124 R140 F144 L147 Y151 V9 I10 Q11 H35 A44 F46 F67 Y70 I71 F74 V78 F81 F85 M87 I93 G95 I96 A97 L111 G113 F120 L121 R137 F141 L144 Y148 P29016 29054999 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGLN 5wl1 A 1.38 BS03 D3D A 1 F10 V12 L66 I69 V72 Y73 G76 F77 A100 V126 C131 F144 I148 I154 M155 T157 V158 L161 Y169 F7 V9 L63 I66 V69 Y70 G73 F74 A97 V123 C128 F141 I145 I151 M152 T154 V155 L158 Y166 P29016 29054999 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGLN 5wos A 2.45 BS01 III B 1 M47 I51 N55 E58 F59 D62 R65 C66 I69 E72 E75 I76 D79 T80 D83 T86 W87 G88 R89 S92 I93 F96 M43 I47 N51 E54 F55 D58 R61 C62 I65 E68 E71 I72 D75 T76 D79 T82 W83 G84 R85 S88 I89 F92 Q6VZT9 29053589 VKKDEIYYTILNIIQNYFIEYCTGKNRNFHVEDENTYIIVKNMCDIILRDNIVEFRKDIDRCSDIENEIPEIVYDTIHDKITWGRVISIIAFGAYVTKVFKEKGRDNVVDLMPDIITESLLSRCRSWLSDQNCWDGLK 5wti Z 2.68 BS01 NUC E 1 T3 S5 S105 E112 A113 N114 Q115 N118 S137 S138 G139 R140 K141 R208 N209 E225 L228 S229 S232 W233 K236 R272 L276 T280 N282 T283 N284 Y286 R294 P327 R328 D332 S397 N398 G483 R485 R494 T513 R769 L770 P772 Q774 N785 R841 M848 S851 R852 R853 R857 T3 S5 S105 E112 A113 N114 Q115 N118 S137 S138 G139 R140 K141 R208 N209 E225 L228 S229 S232 W233 K236 R272 L276 T280 N282 T283 N284 Y286 R294 P327 R328 D332 S388 N389 G474 R476 R485 T504 R732 L733 P735 Q737 N748 R804 M811 S814 R815 R816 R820 A0A0D0F5I0 28374750 MATRSFILKIEPNEEVKKGLWKTHEVLNHGIAYYMNILKLIRQEAIYEHHEQDPKNPKKVSKAEIQAELWDFVLKMQKCNSFTHEVDKDVVFNILRELYEELVPSSVEKKGEANQLSNKFLYPLVDPNSQSGKGTASSGRKPRWYNLKIAGDPSWEEEKKKWEEDKKKDPLAKILGKLAEYGLIPLFIPFTDSNEPIVKEIKWMEKSRNQSVRRLDKDMFIQALERFLSWESWNLKVKEEYEKVEKEHKTLEERIKEDIQAFKSLEQYEKERQEQLLRDTLNTNEYRLSKRGLRGWREIIQKWLKMDENEPSEKYLEVFKDYQRKHPREAGDYSVYEFLSKHPEYPYLYATFCEIDKKKKDAKQQATFTLADPINHPLWVRFEERSGSNLNKYRILTEQLHTEKLKKKLTVQLDRLIYPTESGGWEEKGKVDIVLLPSRQFYNQIFLDIEEKGKHAFTYKDESIKFPLKGTLGGARVQFDRDHLRRYPHKVESGNVGRIYFNMTVNIEPTESPVSKSKELTEWIKDSKGKKLKSGIESLEIGLRVMSIDLGQRQAAAASIFEVVDQKPDIEGKLFFPIKGTELYAVHRASFNIKLPGETLVKSREVLRKAREDNLKLMNQKLNFLRNVLHFQQDITEREKRVTKWISRQENLIQIRELMYKPYKDWVAFLKQLHKRLEVEIGKEVKHWRKSLSDGRKGLYGISLKNIDEIDRTRKFLLRWSLRPTEPGEVRRLEPGQRFAIDQLNHLNALKEDRLKKMANTIIMHALGYCYDVRKKKWQAKNPACQIILFEDLSNYNPYEERSRFENSKLMKWSRREIPRQVALQGEIYGLQVGEVGAQFSSRFHAKTGSPGIRCSVVTKEKLQDLYPDKGGEKFISLSKDRKLVTTHADINAAQNLQKRFWTRTHGFYKVYCKAKIIEEFGEGYFILKDKDSFDLASELKGEKLMLYRDPSGNVFPSDKWMAAGVFFGKLERILISKLTNQ 5wti Z 2.68 BS02 NUC H 1 Q115 N118 Y122 S129 Q130 S131 G132 A136 S138 G139 R140 K141 P142 R143 W162 D165 N209 Q210 S211 V212 R214 S397 K401 R424 Q115 N118 Y122 S129 Q130 S131 G132 A136 S138 G139 R140 K141 P142 R143 W162 D165 N209 Q210 S211 V212 R214 S388 K392 R415 A0A0D0F5I0 28374750 MATRSFILKIEPNEEVKKGLWKTHEVLNHGIAYYMNILKLIRQEAIYEHHEQDPKNPKKVSKAEIQAELWDFVLKMQKCNSFTHEVDKDVVFNILRELYEELVPSSVEKKGEANQLSNKFLYPLVDPNSQSGKGTASSGRKPRWYNLKIAGDPSWEEEKKKWEEDKKKDPLAKILGKLAEYGLIPLFIPFTDSNEPIVKEIKWMEKSRNQSVRRLDKDMFIQALERFLSWESWNLKVKEEYEKVEKEHKTLEERIKEDIQAFKSLEQYEKERQEQLLRDTLNTNEYRLSKRGLRGWREIIQKWLKMDENEPSEKYLEVFKDYQRKHPREAGDYSVYEFLSKHPEYPYLYATFCEIDKKKKDAKQQATFTLADPINHPLWVRFEERSGSNLNKYRILTEQLHTEKLKKKLTVQLDRLIYPTESGGWEEKGKVDIVLLPSRQFYNQIFLDIEEKGKHAFTYKDESIKFPLKGTLGGARVQFDRDHLRRYPHKVESGNVGRIYFNMTVNIEPTESPVSKSKELTEWIKDSKGKKLKSGIESLEIGLRVMSIDLGQRQAAAASIFEVVDQKPDIEGKLFFPIKGTELYAVHRASFNIKLPGETLVKSREVLRKAREDNLKLMNQKLNFLRNVLHFQQDITEREKRVTKWISRQENLIQIRELMYKPYKDWVAFLKQLHKRLEVEIGKEVKHWRKSLSDGRKGLYGISLKNIDEIDRTRKFLLRWSLRPTEPGEVRRLEPGQRFAIDQLNHLNALKEDRLKKMANTIIMHALGYCYDVRKKKWQAKNPACQIILFEDLSNYNPYEERSRFENSKLMKWSRREIPRQVALQGEIYGLQVGEVGAQFSSRFHAKTGSPGIRCSVVTKEKLQDLYPDKGGEKFISLSKDRKLVTTHADINAAQNLQKRFWTRTHGFYKVYCKAKIIEEFGEGYFILKDKDSFDLASELKGEKLMLYRDPSGNVFPSDKWMAAGVFFGKLERILISKLTNQ 5wti Z 2.68 BS03 NUC B 1 T3 R4 S5 K9 R226 W233 V237 D279 T280 R291 K320 Q323 Y333 K367 K372 A375 T376 T378 H385 P386 L387 W388 E412 K413 L414 K415 K417 P446 S447 R448 Q449 Y451 N452 Q487 R490 H492 R495 Y496 K499 N504 G506 R507 Y509 N511 I585 G597 K598 L599 H612 R613 A614 S615 F616 N617 K619 L620 P621 G622 T624 K627 R629 R651 H655 E715 V716 G719 V722 K723 R726 K727 L729 S730 R733 K734 G735 L736 Y737 G738 I739 N743 E746 I747 T750 K752 L754 R756 W757 S758 L759 R760 P761 G765 E766 V767 R768 F776 A777 I778 Q780 H783 A786 L787 D790 K793 K794 N797 T798 H802 Y808 D809 V810 R811 K813 K814 W815 N819 P835 Y836 E837 R841 N844 S845 M848 L861 Q862 H882 K884 V947 T948 T949 H950 I953 Q957 T3 R4 S5 K9 R226 W233 V237 D279 T280 R291 K320 Q323 Y333 K358 K363 A366 T367 T369 H376 P377 L378 W379 E403 K404 L405 K406 K408 P437 S438 R439 Q440 Y442 N443 Q478 R481 H483 R486 Y487 K490 N495 G497 R498 Y500 N502 I560 G572 K573 L574 H587 R588 A589 S590 F591 N592 K594 L595 P596 G597 T599 K602 R604 R626 H630 E678 V679 G682 V685 K686 R689 K690 L692 S693 R696 K697 G698 L699 Y700 G701 I702 N706 E709 I710 T713 K715 L717 R719 W720 S721 L722 R723 P724 G728 E729 V730 R731 F739 A740 I741 Q743 H746 A749 L750 D753 K756 K757 N760 T761 H765 Y771 D772 V773 R774 K776 K777 W778 N782 P798 Y799 E800 R804 N807 S808 M811 L824 Q825 H845 K847 V885 T886 T887 H888 I891 Q895 A0A0D0F5I0 28374750 MATRSFILKIEPNEEVKKGLWKTHEVLNHGIAYYMNILKLIRQEAIYEHHEQDPKNPKKVSKAEIQAELWDFVLKMQKCNSFTHEVDKDVVFNILRELYEELVPSSVEKKGEANQLSNKFLYPLVDPNSQSGKGTASSGRKPRWYNLKIAGDPSWEEEKKKWEEDKKKDPLAKILGKLAEYGLIPLFIPFTDSNEPIVKEIKWMEKSRNQSVRRLDKDMFIQALERFLSWESWNLKVKEEYEKVEKEHKTLEERIKEDIQAFKSLEQYEKERQEQLLRDTLNTNEYRLSKRGLRGWREIIQKWLKMDENEPSEKYLEVFKDYQRKHPREAGDYSVYEFLSKHPEYPYLYATFCEIDKKKKDAKQQATFTLADPINHPLWVRFEERSGSNLNKYRILTEQLHTEKLKKKLTVQLDRLIYPTESGGWEEKGKVDIVLLPSRQFYNQIFLDIEEKGKHAFTYKDESIKFPLKGTLGGARVQFDRDHLRRYPHKVESGNVGRIYFNMTVNIEPTESPVSKSKELTEWIKDSKGKKLKSGIESLEIGLRVMSIDLGQRQAAAASIFEVVDQKPDIEGKLFFPIKGTELYAVHRASFNIKLPGETLVKSREVLRKAREDNLKLMNQKLNFLRNVLHFQQDITEREKRVTKWISRQENLIQIRELMYKPYKDWVAFLKQLHKRLEVEIGKEVKHWRKSLSDGRKGLYGISLKNIDEIDRTRKFLLRWSLRPTEPGEVRRLEPGQRFAIDQLNHLNALKEDRLKKMANTIIMHALGYCYDVRKKKWQAKNPACQIILFEDLSNYNPYEERSRFENSKLMKWSRREIPRQVALQGEIYGLQVGEVGAQFSSRFHAKTGSPGIRCSVVTKEKLQDLYPDKGGEKFISLSKDRKLVTTHADINAAQNLQKRFWTRTHGFYKVYCKAKIIEEFGEGYFILKDKDSFDLASELKGEKLMLYRDPSGNVFPSDKWMAAGVFFGKLERILISKLTNQ 5wti Z 2.68 BS04 MG Z 1 D574 L575 E828 D549 L550 E791 A0A0D0F5I0 28374750 MATRSFILKIEPNEEVKKGLWKTHEVLNHGIAYYMNILKLIRQEAIYEHHEQDPKNPKKVSKAEIQAELWDFVLKMQKCNSFTHEVDKDVVFNILRELYEELVPSSVEKKGEANQLSNKFLYPLVDPNSQSGKGTASSGRKPRWYNLKIAGDPSWEEEKKKWEEDKKKDPLAKILGKLAEYGLIPLFIPFTDSNEPIVKEIKWMEKSRNQSVRRLDKDMFIQALERFLSWESWNLKVKEEYEKVEKEHKTLEERIKEDIQAFKSLEQYEKERQEQLLRDTLNTNEYRLSKRGLRGWREIIQKWLKMDENEPSEKYLEVFKDYQRKHPREAGDYSVYEFLSKHPEYPYLYATFCEIDKKKKDAKQQATFTLADPINHPLWVRFEERSGSNLNKYRILTEQLHTEKLKKKLTVQLDRLIYPTESGGWEEKGKVDIVLLPSRQFYNQIFLDIEEKGKHAFTYKDESIKFPLKGTLGGARVQFDRDHLRRYPHKVESGNVGRIYFNMTVNIEPTESPVSKSKELTEWIKDSKGKKLKSGIESLEIGLRVMSIDLGQRQAAAASIFEVVDQKPDIEGKLFFPIKGTELYAVHRASFNIKLPGETLVKSREVLRKAREDNLKLMNQKLNFLRNVLHFQQDITEREKRVTKWISRQENLIQIRELMYKPYKDWVAFLKQLHKRLEVEIGKEVKHWRKSLSDGRKGLYGISLKNIDEIDRTRKFLLRWSLRPTEPGEVRRLEPGQRFAIDQLNHLNALKEDRLKKMANTIIMHALGYCYDVRKKKWQAKNPACQIILFEDLSNYNPYEERSRFENSKLMKWSRREIPRQVALQGEIYGLQVGEVGAQFSSRFHAKTGSPGIRCSVVTKEKLQDLYPDKGGEKFISLSKDRKLVTTHADINAAQNLQKRFWTRTHGFYKVYCKAKIIEEFGEGYFILKDKDSFDLASELKGEKLMLYRDPSGNVFPSDKWMAAGVFFGKLERILISKLTNQ 5wti Z 2.68 BS05 MG Z 2 Q453 D470 Q444 D461 A0A0D0F5I0 28374750 MATRSFILKIEPNEEVKKGLWKTHEVLNHGIAYYMNILKLIRQEAIYEHHEQDPKNPKKVSKAEIQAELWDFVLKMQKCNSFTHEVDKDVVFNILRELYEELVPSSVEKKGEANQLSNKFLYPLVDPNSQSGKGTASSGRKPRWYNLKIAGDPSWEEEKKKWEEDKKKDPLAKILGKLAEYGLIPLFIPFTDSNEPIVKEIKWMEKSRNQSVRRLDKDMFIQALERFLSWESWNLKVKEEYEKVEKEHKTLEERIKEDIQAFKSLEQYEKERQEQLLRDTLNTNEYRLSKRGLRGWREIIQKWLKMDENEPSEKYLEVFKDYQRKHPREAGDYSVYEFLSKHPEYPYLYATFCEIDKKKKDAKQQATFTLADPINHPLWVRFEERSGSNLNKYRILTEQLHTEKLKKKLTVQLDRLIYPTESGGWEEKGKVDIVLLPSRQFYNQIFLDIEEKGKHAFTYKDESIKFPLKGTLGGARVQFDRDHLRRYPHKVESGNVGRIYFNMTVNIEPTESPVSKSKELTEWIKDSKGKKLKSGIESLEIGLRVMSIDLGQRQAAAASIFEVVDQKPDIEGKLFFPIKGTELYAVHRASFNIKLPGETLVKSREVLRKAREDNLKLMNQKLNFLRNVLHFQQDITEREKRVTKWISRQENLIQIRELMYKPYKDWVAFLKQLHKRLEVEIGKEVKHWRKSLSDGRKGLYGISLKNIDEIDRTRKFLLRWSLRPTEPGEVRRLEPGQRFAIDQLNHLNALKEDRLKKMANTIIMHALGYCYDVRKKKWQAKNPACQIILFEDLSNYNPYEERSRFENSKLMKWSRREIPRQVALQGEIYGLQVGEVGAQFSSRFHAKTGSPGIRCSVVTKEKLQDLYPDKGGEKFISLSKDRKLVTTHADINAAQNLQKRFWTRTHGFYKVYCKAKIIEEFGEGYFILKDKDSFDLASELKGEKLMLYRDPSGNVFPSDKWMAAGVFFGKLERILISKLTNQ 5wti Z 2.68 BS06 MG Z 3 K199 I201 K199 I201 A0A0D0F5I0 28374750 MATRSFILKIEPNEEVKKGLWKTHEVLNHGIAYYMNILKLIRQEAIYEHHEQDPKNPKKVSKAEIQAELWDFVLKMQKCNSFTHEVDKDVVFNILRELYEELVPSSVEKKGEANQLSNKFLYPLVDPNSQSGKGTASSGRKPRWYNLKIAGDPSWEEEKKKWEEDKKKDPLAKILGKLAEYGLIPLFIPFTDSNEPIVKEIKWMEKSRNQSVRRLDKDMFIQALERFLSWESWNLKVKEEYEKVEKEHKTLEERIKEDIQAFKSLEQYEKERQEQLLRDTLNTNEYRLSKRGLRGWREIIQKWLKMDENEPSEKYLEVFKDYQRKHPREAGDYSVYEFLSKHPEYPYLYATFCEIDKKKKDAKQQATFTLADPINHPLWVRFEERSGSNLNKYRILTEQLHTEKLKKKLTVQLDRLIYPTESGGWEEKGKVDIVLLPSRQFYNQIFLDIEEKGKHAFTYKDESIKFPLKGTLGGARVQFDRDHLRRYPHKVESGNVGRIYFNMTVNIEPTESPVSKSKELTEWIKDSKGKKLKSGIESLEIGLRVMSIDLGQRQAAAASIFEVVDQKPDIEGKLFFPIKGTELYAVHRASFNIKLPGETLVKSREVLRKAREDNLKLMNQKLNFLRNVLHFQQDITEREKRVTKWISRQENLIQIRELMYKPYKDWVAFLKQLHKRLEVEIGKEVKHWRKSLSDGRKGLYGISLKNIDEIDRTRKFLLRWSLRPTEPGEVRRLEPGQRFAIDQLNHLNALKEDRLKKMANTIIMHALGYCYDVRKKKWQAKNPACQIILFEDLSNYNPYEERSRFENSKLMKWSRREIPRQVALQGEIYGLQVGEVGAQFSSRFHAKTGSPGIRCSVVTKEKLQDLYPDKGGEKFISLSKDRKLVTTHADINAAQNLQKRFWTRTHGFYKVYCKAKIIEEFGEGYFILKDKDSFDLASELKGEKLMLYRDPSGNVFPSDKWMAAGVFFGKLERILISKLTNQ 5x87 A 3.14 BS02 ZN A 2 D261 A266 D269 D240 A245 D248 W1ELP7 29063836 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKTSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 5xj2 A 2.84 BS01 NUC G 1 T16 H17 E18 F31 K47 F54 R384 R415 T16 H17 E18 F31 K47 F54 R384 R415 2.1.1.- Q97R12 28949991 MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSKLDVD 5xj2 A 2.84 BS02 SAH A 1 F281 Y293 Y312 S313 G314 T317 E333 L334 I335 D359 T360 A361 D381 F281 Y293 Y312 S313 G314 T317 E333 L334 I335 D359 T360 A361 D381 2.1.1.- Q97R12 28949991 MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSKLDVD 5xj2 B 2.84 BS01 ZN B 1 H17 R384 H440 H17 R384 H440 2.1.1.- Q97R12 28949991 MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSKLD 5xj2 B 2.84 BS02 SAH B 1 F281 Y293 Y312 S313 G314 I315 T317 E333 L334 I335 A361 E362 D381 P383 F281 Y293 Y312 S313 G314 I315 T317 E333 L334 I335 A361 E362 D381 P383 2.1.1.- Q97R12 28949991 MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSKLD 5xj2 D 2.84 BS01 ZN D 1 R384 H440 R383 H439 2.1.1.- Q97R12 28949991 LKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSKLDV 5xj2 D 2.84 BS02 SAH D 1 F281 Y293 Y312 S313 G314 T317 I318 E333 L334 I335 D359 T360 A361 D381 P383 F280 Y292 Y311 S312 G313 T316 I317 E332 L333 I334 D358 T359 A360 D380 P382 2.1.1.- Q97R12 28949991 LKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSKLDV 5xkx A 1.50 BS01 ZN A 1 H265 E269 H338 H244 E248 H317 N8X9V6 AQFQCQDDVKPTSYTTEEQKLVDQFWNESLIYLDQYLKALETPTGQCKDSAQATIQTYNSETGKMQTQCIMKYRDVELVAKHLKAVLAEPDKAKACFDPQKNYKAFPLYTPSAHVQNLSATSKWINRPLLTDYYKKIGGEIGAAGLELNENFLEITSRTDTTLHWTKDVSIKGLPTLWSSVGWIPFYAENPNAGSDRFRGGYLYAEVMGPWGNLRIKEIDGEKVGAEIGMTAQLFNTSYPYHYHHPQEIYMTLTKPQCIDQNKHMVMHWDNNQFKQKRSDNGWTVNIDGSKGKWKKWFSNQDPEQNWLTYFERNAIHAFHTLEGCNQTIKNSGLVTVWARTTAQDNNQTTQLCRPMTGAKDIKTMKPEDKAICDLDDWKP 5xr2 C 2.60 BS01 ZN C 1 H295 H299 H290 H294 3.1.2.-,3.5.1.124 P64312 29046369 NELSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNKLEHHHHHH 5xr3 E 3.01 BS01 GLV E 1 D177 D181 D170 D174 3.1.2.-,3.5.1.124 P64312 29046369 LSKQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK 5xup A 2.10 BS01 III C 1 R102 A105 E106 I109 H110 C126 Q127 T130 R131 L138 D139 A140 Q141 F142 E143 N144 E146 R38 A41 E42 I45 H46 C62 Q63 T66 R67 L74 D75 A76 Q77 F78 E79 N80 E82 P54274 GLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVES 5xup B 2.10 BS01 III D 1 R102 A105 E106 I109 C126 Q127 T130 R131 A140 Q141 F142 N144 R38 A41 E42 I45 C62 Q63 T66 R67 A76 Q77 F78 N80 P54274 GLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVE 5ydt 5 4.50 BS01 NUC A 1 H37 N41 R50 R84 R109 G112 S113 L115 Y119 R142 H145 G146 S147 K148 I190 N192 D194 N195 C196 S198 K245 S247 N248 S251 H27 N31 R40 R74 R99 G102 S103 L105 Y109 R132 H135 G136 S137 K138 I180 N182 D184 N185 C186 S188 K235 S237 N238 S241 28951391 GLAEKALKALILQCEENPSLKNDKDIHIIINTGKKMGINRDNIPRIIPLTKYKLFKPRDLNILLITKDPSALYRETLTKDEHTSELFKEIISVKNLRRRFKGSKLTQLYKDFDLVVADYRVHHLLPEVLGSRFYHGSKKLPYMIRMSKEVKLKRQQMVEKCDPIYVRAQLRSICKNTSYIPNNDNCLSVRVGYIQKHSIPEILQNIQDTINFLTDKSKRPQGGVIKGGIISIFVKTSNSTSLPIYQ 6amb A 2.50 BS01 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 V29 D30 Y32 P34 T35 G60 Q61 N116 K117 D119 S145 A146 K147 G14 G15 V16 G17 K18 S19 A20 F30 V31 D32 Y34 P36 T37 G62 Q63 N118 K119 D121 S147 A148 K149 P01112 HMMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKL 6apx A 2.49 BS01 SO4 A 1 A370 G1172 H1188 R1292 A367 G368 H384 R488 3.1.3.16,3.1.3.48 P28562 29052270 IEELVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLA 6apx A 2.49 BS02 SO4 A 2 Q72 S1207 A1208 N1209 E1226 Q1259 R1264 Q69 S403 A404 N405 E422 Q455 R460 3.1.3.16,3.1.3.48 P28562 29052270 IEELVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALAAAQTNAAAGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLA 6b57 A 1.93 BS01 UNX A 1 G357 I359 R374 G58 I60 R75 Q9Y2W6 GRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELTGRAR 6b57 A 1.93 BS02 UNX A 2 Y311 S313 Q324 Y12 S14 Q25 Q9Y2W6 GRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELTGRAR 6b57 A 1.93 BS03 UNX A 3 E345 G368 W370 E46 G69 W71 Q9Y2W6 GRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELTGRAR 6b57 A 1.93 BS04 UNX A 4 P349 E350 K400 L402 R403 P50 E51 K101 L103 R104 Q9Y2W6 GRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELTGRAR 6b57 A 1.93 BS05 UNX A 5 T461 I463 T465 T162 I164 T166 Q9Y2W6 GRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELTGRAR 6b57 A 1.93 BS06 UNX A 6 A314 S315 A513 R514 A15 S16 A200 R201 Q9Y2W6 GRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELTGRAR 6b57 B 1.93 BS01 UNX B 1 N394 R512 A513 N96 R199 A200 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS02 UNX B 2 A446 D447 W448 R518 G519 A148 D149 W150 R205 G206 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS03 UNX B 3 S315 D440 C445 R514 R516 S17 D142 C147 R201 R203 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS04 UNX B 4 Y387 V389 A416 Y89 V91 A118 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS05 UNX B 5 Y470 D481 G483 L484 Y172 D183 G185 L186 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS06 UNX B 6 Y371 R372 F388 V389 D390 F391 Y73 R74 F90 V91 D92 F93 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS07 UNX B 7 L336 V337 M340 W370 Y371 L38 V39 M42 W72 Y73 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS08 UNX B 8 Y371 F391 W448 G519 R520 Y73 F93 W150 G206 R207 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS09 UNX B 9 Y311 W448 P450 Y13 W150 P152 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS10 UNX B 10 T474 N476 G477 T176 N178 G179 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b57 B 1.93 BS11 UNX B 11 F391 W448 R518 G519 F93 W150 R205 G206 Q9Y2W6 SGRENLYFQGEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELGRARARARGR 6b6p A 2.00 BS02 XYP A 1 V76 E80 Q81 F82 V58 E62 Q63 F64 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6p A 2.00 BS03 XYS A 1 N97 Q175 N79 Q155 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS02 EOH A 1 Y20 C22 T26 L137 C157 Y5 C7 T11 L117 C137 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS03 EOH A 2 V76 E80 F82 V58 E62 F64 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS04 EOH A 3 R66 I73 N74 V75 V76 R49 I55 N56 V57 V58 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS05 EOH A 4 Q135 C136 L137 K159 Q115 C116 L117 K139 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS06 EOH A 5 Y39 H40 I73 N74 Y22 H23 I55 N56 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS07 EOH A 6 V17 K145 S146 S147 V2 K125 S126 S127 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS08 EOH A 7 N97 T98 L99 W215 N79 T80 L81 W193 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS09 EOH A 8 Q64 F82 S84 Q47 F64 S66 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6b6s A 2.00 BS10 EOH A 9 A129 F181 Q210 K230 A110 F161 Q188 K208 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 6baa A 3.63 BS01 ATP A 1 I182 F183 S184 K185 L205 Y330 S331 F333 G334 I151 F152 S153 K154 L174 Y299 S300 F302 G303 P70673 29035201 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDED 6baa E 3.63 BS01 GBM E 1 R306 Y377 M429 W430 F433 L434 N437 M441 T588 L592 S1238 T1242 N1245 R1246 R290 Y336 M378 W379 F382 L383 N386 M390 T537 L541 S1005 T1009 N1012 R1013 Q09427 29035201 CGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIAKLPIAMRALTNYQRLCVAFDAARAIWRALCHAFGRRLILSSTFRILADLLGFAGPLCIFGIVDHLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHMSAGQICNLVAIDTNQLMWFFFLCPNLWTMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRTTLEHSNERLKQTNEMLRGMKLLKLYAWESIFCSRVEVTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDLSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSNLPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQQTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDYAMVFTLLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLVSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVCMEYIGACVVLIAAATSISNSLSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHALLGKIQIQNLSVRYDSSLKPVLKHVNTLISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPETLLSQKDSVFASF 6egu A 2.30 BS01 43Y A 1 R775 R776 C777 V780 C825 F826 D961 R82 R83 C84 V87 C132 F133 D268 A2T087 CSELIQASSRITTCSTETKCRLSGTALIRAGSVGAEACLMLKGVKEDQTKFLKIKTVSSELSCREGQSYWTGSFSPKCLSSRRCHLVGECHVNRCLSWRDNETSAEFSFVGESTTMRENKCFEQCGGHGCGCFNVNPSCLFVHTYLQSVRKEALRVFNCIDWVHKLTLEITDFDGSVSTIDLGASSSRFTNWGSVSLSLDAEGISGSNSFSFIESPGKGYAIVDEPFSEIPRQGFLGEIRCNSESSVLSAHESCLRAPNLISYKPMIDQLECTTNLIDPFVVFERGSLPQTRNDKTFAASKGNRGVQAFSKGSVQADLTLMFDNFEVDFVGAAVSCDAAFLNLTGCYSCNAGARVCLSITSTGTGTLSAHNKDGSLHIVLPSENGTKDQCQILHFTVPEVEEEFMYSCDGDERPLLVKGTLIAIDPFDDRREAGGESTVVNPK 6egu B 2.30 BS01 43Y B 1 R775 R776 C777 V780 G824 C825 F826 D961 R81 R82 C83 V86 G130 C131 F132 D267 A2T087 CSELIQASSRITTCSTTKCRLSGTALIRAGSVGAEACLMLKGVKEDQTKFLKIKTVSSELSCREGQSYWTGSFSPKCLSSRRCHLVGECHVNRCLSWRDNETSAEFSFVGESTTMRENKCFEQCGGHGCGCFNVNPSCLFVHTYLQSVRKEALRVFNCIDWVHKLTLEITDFDGSVSTIDLGASSSRFTNWGSVSLSLDAEGISGSNSFSFIESPGKGYAIVDEPFSEIPRQGFLGEIRCNSESSVLSAHESCLRAPNLISYKPMIDQLECTTNLIDPFVVFERGSLPQTRNDKTFAASKGNRGVQAFSKGSVQADLTLMFDNFEVDFVGAAVSCDAAFLNLTGCYSCNAGARVCLSITSTGTGTLSAHNKDGSLHIVLPSENGTKDQCQILHFTVPEVEEEFMYSCDGDERPLLVKGTLIAIDPFDDRREAGGESTVVN 6eim A 1.43 BS01 B6E A 1 L42 A63 K65 E81 I84 I93 V94 I110 E111 F112 C113 P114 G116 L148 H155 L164 A174 D175 F176 L183 L186 L17 A32 K34 E50 I53 I62 V63 I79 E80 F81 C82 P83 G85 L117 H124 L133 A143 D144 F145 L152 L155 2.7.11.1 O94804 VRRDLDPNEVWEIVGELKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLAIAASDPPTLLTPSKWSVEFRDFLAIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 6eim B 1.43 BS01 B6E B 1 L42 V50 A63 K65 E81 I84 L85 I93 V94 I110 E111 F112 C113 P114 G116 L148 L164 A174 D175 F176 L183 L186 L20 V28 A41 K43 E59 I62 L63 I71 V72 I88 E89 F90 C91 P92 G94 L126 L142 A152 D153 F154 L161 L164 2.7.11.1 O94804 YEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLAIAASDPPTLLTPSKWSVEFRDFLAIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE 6enx A 1.95 BS02 BJW A 1 G54 A55 G56 T65 F66 R67 W73 Y98 R101 Q136 I138 H154 V216 V217 W218 F219 G220 E221 T222 G245 T246 S247 I249 V250 Y251 N271 M272 E273 P288 C289 G23 A24 G25 T34 F35 R36 W42 Y67 R70 Q105 I107 H123 V185 V186 W187 F188 G189 E190 T191 G214 T215 S216 I218 V219 Y220 N240 M241 E242 P257 C258 3.5.1.- Q6DHI5 29044784 PSSDLTAFREHFAKAKHIAIITGAGVSAESGVPTFRGPGGFWRKWQAQDLATPEAFSRDPSLVWEFYHYRREVMRSKMPNPAHLAIAECEARLGQQGRSVVIITQNIDELHHRAGSKHVYEIHGSLFKTRCMSCGEVKANHKSPICPALDGKGAPDPNTKEARIPVELLPRCERKSCNGLLRPHVVWFGETLDSDILTAVERELEKCDLCLVVGTSSIVYPAAMFAPQVASRGVPVAEFNMECTPATQRFKYHFEGPCGSTLPPALE 6eo0 A 2.40 BS02 BV8 A 1 G54 A55 G56 A59 E60 T65 F66 R67 Y98 R101 Q136 H154 V217 F219 G220 E221 T222 L223 G245 T246 S247 V250 Y251 N271 M272 E273 C289 G30 A31 G32 A35 E36 T41 F42 R43 Y74 R77 Q112 H130 V193 F195 G196 E197 T198 L199 G221 T222 S223 V226 Y227 N247 M248 E249 C265 3.5.1.- Q6DHI5 29044784 PFTKMTRPSSDLTAFREHFAKAKHIAIITGAGVSAESGVPTFRGPGGFWRKWQAQDLATPEAFSRDPSLVWEFYHYRREVMRSKMPNPAHLAIAECEARLGQQGRSVVIITQNIDELHHRAGSKHVYEIHGSLFKTRCMSCGEVKANHKSPICPALDGKGAPDPNTKEARIPVELLPRCERKSCNGLLRPHVVWFGETLDSDILTAVERELEKCDLCLVVGTSSIVYPAAMFAPQVASRGVPVAEFNMECTPATQRFKYHFEGPCGSTLPPALE 6eo0 A 2.40 BS03 BVT A 1 G54 A55 G56 A59 E60 T65 F66 R67 A82 Y98 R101 Q136 I138 H154 V217 F219 G220 E221 T222 L223 G245 T246 S247 V250 Y251 N271 M272 E273 P288 C289 G30 A31 G32 A35 E36 T41 F42 R43 A58 Y74 R77 Q112 I114 H130 V193 F195 G196 E197 T198 L199 G221 T222 S223 V226 Y227 N247 M248 E249 P264 C265 3.5.1.- Q6DHI5 29044784 PFTKMTRPSSDLTAFREHFAKAKHIAIITGAGVSAESGVPTFRGPGGFWRKWQAQDLATPEAFSRDPSLVWEFYHYRREVMRSKMPNPAHLAIAECEARLGQQGRSVVIITQNIDELHHRAGSKHVYEIHGSLFKTRCMSCGEVKANHKSPICPALDGKGAPDPNTKEARIPVELLPRCERKSCNGLLRPHVVWFGETLDSDILTAVERELEKCDLCLVVGTSSIVYPAAMFAPQVASRGVPVAEFNMECTPATQRFKYHFEGPCGSTLPPALE 6eo0 B 2.40 BS02 BVT B 1 G54 A55 G56 A59 E60 T65 F66 R67 A82 Y98 R101 Q136 I138 H154 V217 F219 G220 E221 T222 G245 T246 S247 V250 Y251 P252 N271 M272 P288 C289 G31 A32 G33 A36 E37 T42 F43 R44 A59 Y75 R78 Q113 I115 H131 V194 F196 G197 E198 T199 G222 T223 S224 V227 Y228 P229 N248 M249 P265 C266 3.5.1.- Q6DHI5 29044784 DPFTKMTRPSSDLTAFREHFAKAKHIAIITGAGVSAESGVPTFRGPGGFWRKWQAQDLATPEAFSRDPSLVWEFYHYRREVMRSKMPNPAHLAIAECEARLGQQGRSVVIITQNIDELHHRAGSKHVYEIHGSLFKTRCMSCGEVKANHKSPICPALDGKGAPDPNTKEARIPVELLPRCERKSCNGLLRPHVVWFGETLDSDILTAVERELEKCDLCLVVGTSSIVYPAAMFAPQVASRGVPVAEFNMECTPATQRFKYHFEGPCGSTLPPALE 6eoe A 1.71 BS01 ADP A 1 G36 T37 T38 Y39 G226 G227 G255 E293 K296 R297 S300 G363 G364 S365 R367 I368 D391 G8 T9 T10 Y11 G198 G199 G227 E265 K268 R269 S272 G335 G336 S337 R339 I340 D363 G3I8R9 29064368 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGAFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKITITNDQNRLTPEEIERMVNDAEKF 6eqs A 1.32 BS02 BV8 A 1 G58 A59 G60 A63 E64 T69 F70 R71 Y102 R105 Q140 I142 H158 V221 W222 F223 G224 E225 N226 G249 T250 S251 V253 V254 Y255 N275 T276 E277 P292 C293 G25 A26 G27 A30 E31 T36 F37 R38 Y69 R72 Q107 I109 H125 V188 W189 F190 G191 E192 N193 G216 T217 S218 V220 V221 Y222 N242 T243 E244 P259 C260 3.5.1.- Q9NXA8 29044784 ARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs A 1.32 BS03 BU2 A 1 C181 P182 K203 L204 P205 R206 E208 C148 P149 K170 L171 P172 R173 E175 3.5.1.- Q9NXA8 29044784 ARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs B 1.32 BS03 BU2 B 1 P68 T69 F70 G74 G75 Y76 A82 P34 T35 F36 G40 G41 Y42 A48 3.5.1.- Q9NXA8 29044784 RPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs B 1.32 BS04 BU2 B 2 R71 Q83 S251 V254 R37 Q49 S217 V220 3.5.1.- Q9NXA8 29044784 RPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs C 1.32 BS03 BU2 C 1 F70 R71 Q83 S251 V253 V254 F42 R43 Q55 S223 V225 V226 3.5.1.- Q9NXA8 29044784 IDPFTARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs D 1.32 BS02 BV8 D 1 G58 A59 G60 E64 T69 F70 R71 Q83 A86 Y102 R105 Q140 I142 H158 V221 W222 F223 G224 E225 G249 T250 S251 V254 Y255 N275 T276 E277 P292 C293 G31 A32 G33 E37 T42 F43 R44 Q56 A59 Y75 R78 Q113 I115 H131 V194 W195 F196 G197 E198 G222 T223 S224 V227 Y228 N248 T249 E250 P265 C266 3.5.1.- Q9NXA8 29044784 GIDPFTARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs D 1.32 BS03 BU2 D 1 H103 E107 G186 K187 H76 E80 G159 K160 3.5.1.- Q9NXA8 29044784 GIDPFTARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqs D 1.32 BS04 BU2 D 2 E123 T126 E96 T99 3.5.1.- Q9NXA8 29044784 GIDPFTARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 6eqz D 2.29 BS01 MAL D 1 K15 W62 A63 D65 R66 E111 E153 P154 Y155 M340 W350 K15 W62 A63 D65 R66 E111 E153 P154 Y155 M340 W350 P0AEY0 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFLKEKRITNTEAAIDTGKETVGVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNSS