5h6o A 2.70 BS01 DPM A 1 S87 K89 D90 C134 S135 R137 R138 R161 A176 R182 A201 Q204 G205 C248 S59 K61 D62 C106 S107 R109 R110 R133 A148 R154 A173 Q176 G177 C220 2.5.1.61 A0A0H6VB38 TPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAKEIL 5h6o A 2.70 BS02 MG A 1 L21 V158 L12 V130 2.5.1.61 A0A0H6VB38 TPIRIATRQSPLALWQANYVKDALMAAHPGLQVELVTMVFVKELEIAMLEGRADLAVHSMKDVPVDFPDGLGLVTICEREDPRDAFVSNTYAKIEDLPSGAIVGTCSLRRQCQLKAARPDLVIKELRGNVGTRLSKLDAGEYDAIILAAAGLKRLELESRIRSFIEPEQSLPAVGQGAVGIECRVNDQRVRALLAPLNHADTADRVRCERAMNLTLQGGCQVPIGSYALLEGDTIWLRALVGEPDGSQIVRGEIRGPRTQAEQLGITLAEQLLSQGAKEIL 5h6y A 2.00 BS01 III B 1 D101 A102 Y147 N148 P149 F154 D41 A42 Y87 N88 P89 F94 Q12830 TAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTAIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRS 5j5z A 1.84 BS01 FAD A 1 I12 G13 G15 P16 G17 E36 K37 N38 G43 T44 C45 V48 G49 C50 S53 K54 G117 Y118 G119 A147 T148 G149 S150 S168 I189 R280 F283 G319 D320 M326 L327 A328 H329 Y359 I15 G16 G18 P19 G20 E39 K40 N41 G46 T47 C48 V51 G52 C53 S56 K57 G120 Y121 G122 A150 T151 G152 S153 S171 I192 R283 F286 G322 D323 M329 L330 A331 H332 Y362 1.8.1.4 P09622 VLFADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEVIARVCHAHPTLSEAFREANLAASFGKSINF 5jri A 1.95 BS01 FAD A 1 G26 G27 G28 M29 G30 V48 E49 K50 G51 R52 G53 R54 S55 W57 M58 Q59 L61 R62 N63 G94 Y95 V96 A130 T131 D135 G151 V156 C160 H258 G292 D293 N299 Q300 V301 A304 G11 G12 G13 M14 G15 V33 E34 K35 G36 R37 G38 R39 S40 W42 M43 Q44 L46 R47 N48 G79 Y80 V81 A115 T116 D120 G136 V141 C145 H243 G277 D278 N284 Q285 V286 A289 LDTVYDAIVLGGGMGGLSAAIYLARYGLKCLVVEKGRGRSFWMQDLRNYVGLDPDTPGRDIITHSTQQALHWGADLLRGYVEDVTDEGDTLAVKVKVGKKDSLYPIFRTKYVIAATGIIDNLPQLEDMQNVYDYAGYTLHVCMICDGFDMWDQKAVLIAGTEGQINAAFVLNWFTPYITVLTHGLCTVGDEMKAKLADHGYPLHEAAITKFLGEDHKMSGVELVDGTVMEATTGLINMGSVYHNHYLKGIEGLEWDGENLVTNDMAQTSHPRIFALGDLKKGLNQVSVAVADGTLAATQIWRNIRRASEPRKWIH 5jri A 1.95 BS02 FAD A 2 K50 W57 Y95 E97 K111 G113 I134 D135 L137 Y147 A150 G151 V156 K35 W42 Y80 E82 K96 G98 I119 D120 L122 Y132 A135 G136 V141 LDTVYDAIVLGGGMGGLSAAIYLARYGLKCLVVEKGRGRSFWMQDLRNYVGLDPDTPGRDIITHSTQQALHWGADLLRGYVEDVTDEGDTLAVKVKVGKKDSLYPIFRTKYVIAATGIIDNLPQLEDMQNVYDYAGYTLHVCMICDGFDMWDQKAVLIAGTEGQINAAFVLNWFTPYITVLTHGLCTVGDEMKAKLADHGYPLHEAAITKFLGEDHKMSGVELVDGTVMEATTGLINMGSVYHNHYLKGIEGLEWDGENLVTNDMAQTSHPRIFALGDLKKGLNQVSVAVADGTLAATQIWRNIRRASEPRKWIH 5k0a A 1.71 BS02 FAD A 2 K50 R52 W57 Y95 E97 K111 G113 K114 I134 D135 L137 Y147 A150 G151 V156 K40 R42 W47 Y85 E87 K101 G103 K104 I124 D125 L127 Y137 A140 G141 V146 P74746 NLDARLDTVYDAIVLGGGMGGLSAAIYLARYGLKCLVVEKGRGRSFWMQDLRNYVGLDPDTPGRDIITHSTQQALHWGADLLRGYVEDVTDEGDTLAVKVKVGKKDSLYPIFRTKYVIAATGIIDNLPQLEDMQNVYDYAGYTLHVCMICDGFDMWDQKAVLIAGTEGQINAAFVLNWFTPYITVLTHGLCTVGDEMKAKLADHGYPLHEAAITKFLGEDHKMSGVELVDGTVMEATTGLINMGSVYHNHYLKGIEGLEWDGENLVTNDMAQTSHPRIFALGDLKKGLNQVSVAVADGTLAATQIWRNIRRASEPRKWIH 5k4q A 2.30 BS01 NAD A 1 G1009 L1011 G1012 Q1013 I1014 D1035 V1036 L1054 D1055 C1056 L1077 P1078 A1079 M1081 P1117 S1118 T1119 Y1144 K1148 L1171 P1172 I1174 G8 L10 G11 Q12 I13 D34 V35 L53 D54 C55 L76 P77 A78 M80 P116 S117 T118 Y143 K147 L170 P171 I173 1.1.1.103 Q7YW97 MPRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKGVEKLDCLDSNGFEKLVKEFKPTWMYHLPAIMSVRGEAEPDLAMDINVNTTRYALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVYTELLGTWYRQKYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQKKCVCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVYNITGFSFSPSELRFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYDIDMMSEDMLRQIPILHGLPSL 5k4q F 2.30 BS01 NAD F 1 G6009 G6012 Q6013 I6014 D6035 V6036 L6054 D6055 C6056 L6077 P6078 A6079 M6081 I6095 P6117 S6118 Y6144 K6148 L6171 P6172 I6174 G7 G10 Q11 I12 D33 V34 L52 D53 C54 L75 P76 A77 M79 I93 P115 S116 Y142 K146 L169 P170 I172 1.1.1.103 Q7YW97 PRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKGVEKLDCLDSNGFEKLVKEFKPTWMYHLPAIMSVRGEAEPDLAMDINVNTTRYALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVYTELLGTWYRQKYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQKKCVCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVYNITGFSFSPSELRFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYDIDMMSEDMLRQIPILHGLPSL 5k4u A 1.90 BS01 NAD A 1 G6009 L6011 G6012 Q6013 I6014 D6035 V6036 L6054 D6055 C6056 L6077 P6078 M6081 I6095 P6117 S6118 T6119 Y6144 K6148 L6171 P6172 G6173 I6174 G6182 G8 L10 G11 Q12 I13 D34 V35 L53 D54 C55 L76 P77 M80 I94 P116 S117 T118 Y143 K147 L170 P171 G172 I173 G181 1.1.1.103 Q7YW97 MPRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKGVEKLDCLDSNGFEKLVKEFKPTWMYHLPAIMSVRGEAEPDLAMDINVNTTRYALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVYTELLGTWYRQKYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQKKCVCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVYNITGFSFSPSELRFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYDIDMMSEDMLRQIPILHGLPSL 5k50 C 2.26 BS02 ALO C 1 M1081 S1082 T1119 I1120 Y1144 A1185 T1186 W1280 M79 S80 T117 I118 Y142 A183 T184 W278 1.1.1.103 Q7YW97 PRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKGVEKLDCLDSNGFEKLVKEFKPTWMYHLPAIMSVRGEAEPDLAMDINVNTTRYALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVYTELLGTWYRQKYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQKKCVCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVYNITGFSFSPSELRFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYDIDMMSEDMLRQIPILHGLPSL 5lef A 2.09 BS01 GTP A 1 Q22 S23 V24 G25 K26 T27 S28 F38 D39 N40 Y42 A44 T45 G71 N126 K127 D129 L130 S156 A157 K158 Q12 S13 V14 G15 K16 T17 S18 F28 D29 N30 Y32 A34 T35 G61 N116 K117 D119 L120 S146 A147 K148 P20340 29093437 LRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGLERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPG 5lil A 3.35 BS01 ATP A 1 F13 V22 S42 G43 S44 G45 K46 S47 T48 Q92 Q169 H201 F13 V22 S42 G43 S44 G45 K46 S47 T48 Q92 Q169 H201 3.6.3.- Q2EHL8 29109272 MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSLTAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQRVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGEIISDTQKRQVKSAVKNPSVFSKDQLMEAFRMSVSAIVAHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFQNLKISDANTLSKQSYIQSVTPNTSSSGILVVGNKSFTSANLYGIGEQYFDVEGLKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFANENPLGKTVIFNKRPFRVIGVVSDQSLNLYSPYSTVLNKITGGSRIGSITVKISDDVNSTVAEKSLTELLKSLHGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLVSVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGVLFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALA 5lil A 3.35 BS02 MG A 1 S47 Q92 D168 S47 Q92 D168 3.6.3.- Q2EHL8 29109272 MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSLTAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQRVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGEIISDTQKRQVKSAVKNPSVFSKDQLMEAFRMSVSAIVAHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFQNLKISDANTLSKQSYIQSVTPNTSSSGILVVGNKSFTSANLYGIGEQYFDVEGLKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFANENPLGKTVIFNKRPFRVIGVVSDQSLNLYSPYSTVLNKITGGSRIGSITVKISDDVNSTVAEKSLTELLKSLHGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLVSVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGVLFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALA 5lil A 3.35 BS03 ATP B 1 K136 N142 Q143 L144 S145 G147 Q148 K136 N142 Q143 L144 S145 G147 Q148 3.6.3.- Q2EHL8 29109272 MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSLTAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQRVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGEIISDTQKRQVKSAVKNPSVFSKDQLMEAFRMSVSAIVAHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFQNLKISDANTLSKQSYIQSVTPNTSSSGILVVGNKSFTSANLYGIGEQYFDVEGLKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFANENPLGKTVIFNKRPFRVIGVVSDQSLNLYSPYSTVLNKITGGSRIGSITVKISDDVNSTVAEKSLTELLKSLHGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLVSVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGVLFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALA 5lj7 A 3.25 BS01 ATP A 1 F13 V22 S42 G43 S44 G45 K46 S47 T48 Q92 Q169 H201 F13 V22 S42 G43 S44 G45 K46 S47 T48 Q92 Q169 H201 3.6.3.- Q2EHL8 29109272 MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSLTAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQRVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGEIISDTQKRQVKSAVKNPSVFSKDQLMEAFRMSVSAIVAHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFQNLKISDANTLSKQSYIQSVTPNTANLYGIGEQYFDVEGLKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFVIFNKRPFRVIGVVSDQSLNLYSPYSTVLNKITGGSRIGSITVKISDDVNSTVAEKSLTELLKSLHGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLVSVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGVLFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALAQ 5lj7 A 3.25 BS02 MG A 1 S47 Q92 D168 S47 Q92 D168 3.6.3.- Q2EHL8 29109272 MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSLTAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQRVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGEIISDTQKRQVKSAVKNPSVFSKDQLMEAFRMSVSAIVAHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFQNLKISDANTLSKQSYIQSVTPNTANLYGIGEQYFDVEGLKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFVIFNKRPFRVIGVVSDQSLNLYSPYSTVLNKITGGSRIGSITVKISDDVNSTVAEKSLTELLKSLHGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLVSVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGVLFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALAQ 5lj7 A 3.25 BS03 ATP B 1 K136 N142 Q143 L144 S145 G147 Q148 K136 N142 Q143 L144 S145 G147 Q148 3.6.3.- Q2EHL8 29109272 MNIIEIKQLNRYFGEGENRVHVLKDISLSIERGDFVAIMGQSGSGKSTLMNIIGCLDTATGGSSKIDGKETIELTNDQLSDLRSQKFGFIFQRYNLLSSLTAAENVALPAIYAGMPQSQRLERAKQLLEKLGLGDKWQNKPNQLSGGQQQRVSIARALMNGGEIILADQPTGALDSHSGENVMEILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGEIISDTQKRQVKSAVKNPSVFSKDQLMEAFRMSVSAIVAHKMRSLLTMLGIIIGITSVVSVVALGNGSQQKILENIRGIGTNTMTIFQNLKISDANTLSKQSYIQSVTPNTANLYGIGEQYFDVEGLKLKQGRLLTEDDVDQSNQVVVLDESAKKAIFVIFNKRPFRVIGVVSDQSLNLYSPYSTVLNKITGGSRIGSITVKISDDVNSTVAEKSLTELLKSLHGKKDFFIMNSDTIKQTIENTTGTMKLLISSIAFISLIVGGIGVMNIMLVSVTERTKEIGVRMAIGARQINILQQFLIEAVLICLIGGVAGILLSVLIGVLFNSFITDFSMDFSTASIVTAVLFSTLIGVLFGYMPAKKAAELNPITALAQ 5m2t A 1.03 BS01 URI A 1 I68 G69 T93 T94 G95 F161 Q165 E195 M196 E197 I66 G67 T91 T92 G93 F159 Q163 E193 M194 E195 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5m2t A 1.03 BS02 URI B 1 F6 H7 F4 H5 2.4.2.3 Q9K4U1 KTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5m2t B 1.03 BS02 URI B 1 I68 R90 T93 T94 G95 F161 Q165 R167 E195 M196 E197 I219 I220 I67 R89 T92 T93 G94 F160 Q164 R166 E194 M195 E196 I218 I219 2.4.2.3 Q9K4U1 TKTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5m2t E 1.03 BS01 URI E 1 I68 T93 T94 G95 F161 Q165 R167 E195 M196 E197 I219 I220 I67 T92 T93 G94 F160 Q164 R166 E194 M195 E196 I218 I219 2.4.2.3 Q9K4U1 TKTVFHLGVTEADLNGATLAIIPGDPARVQKIAELMDNPVFLASHREYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGVIINRTQKEIPDHATLKETEARSIKVVVEAARKMLK 5m36 A 2.45 BS02 9SZ A 1 R60 S64 Q67 Y179 E180 R59 S63 Q66 Y175 E176 P63104 29039919 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDSYKDSTLIMQLLRDNLTLWTS 5m36 B 2.45 BS01 III C 1 E14 Q15 E39 V46 K49 R56 R60 R127 Y128 L172 N173 V176 E180 D213 L216 I217 L220 N224 E13 Q14 E38 V45 K48 R55 R59 R123 Y124 L168 N169 V172 E176 D203 L206 I207 L210 N214 P63104 29039919 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDYKDSTLIMQLLRDNLTLWT 5m36 B 2.45 BS03 9SZ C 1 R60 Q67 Y179 E180 R59 Q66 Y175 E176 P63104 29039919 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDYKDSTLIMQLLRDNLTLWT 5m37 A 2.35 BS01 III D 1 S45 K49 R56 R60 V61 S64 R127 Y128 G169 L172 N173 V176 E180 K212 D213 I217 L220 N224 W228 S45 K49 R56 R60 V61 S64 R127 Y128 G169 L172 N173 V176 E180 K212 D213 I217 L220 N224 W228 P63104 29039919 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 5m37 A 2.35 BS03 9SZ D 1 W59 R60 S63 Q67 Y179 E180 W59 R60 S63 Q67 Y179 E180 P63104 29039919 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 5m37 B 2.35 BS01 III C 1 E14 V46 K49 N50 R56 R60 V61 S64 R127 Y128 G169 L172 N173 V176 E180 K212 D213 I217 L220 N224 E13 V45 K48 N49 R55 R59 V60 S63 R124 Y125 G166 L169 N170 V173 E177 K209 D210 I214 L217 N221 P63104 29039919 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 5m37 B 2.35 BS02 9SZ B 1 K74 Q77 M78 K71 Q74 M75 P63104 29039919 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 5m37 B 2.35 BS03 9SZ C 1 W59 S63 Q67 Y179 E180 N183 W58 S62 Q66 Y176 E177 N180 P63104 29039919 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 5m6r A 2.73 BS01 7J8 A 1 G72 E73 S96 K98 D99 L100 P101 T102 S146 S147 R149 R150 R173 A189 R195 A214 V215 Q217 G218 L254 G260 C261 S262 G55 E56 S79 K81 D82 L83 P84 T85 S129 S130 R132 R133 R156 A172 R178 A197 V198 Q200 G201 L237 G243 C244 S245 2.5.1.61 P08397 MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVARQL 5m7f A 2.78 BS01 DPM A 1 S96 K98 D99 S146 S147 R149 R150 L170 R173 L188 A189 A191 G192 R195 A214 Q217 G218 C261 S60 K62 D63 S110 S111 R113 R114 L134 R137 L152 A153 A155 G156 R159 A178 Q181 G182 C225 2.5.1.61 P08397 VIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDV 5m7f B 2.78 BS01 DPM B 1 L30 Q34 S96 K98 D99 S146 S147 R149 R150 R173 I187 L188 A189 G192 R195 A214 Q217 G218 C261 L11 Q15 S59 K61 D62 S109 S110 R112 R113 R136 I150 L151 A152 G155 R158 A177 Q180 G181 C224 2.5.1.61 P08397 VIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDV 5mey A 2.05 BS01 NUC D 1 T77 L78 L82 Q83 A85 G86 K88 T63 L64 L68 Q69 A71 G72 K74 Q13485 ACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 5mez A 2.98 BS02 NUC E 1 K45 R81 K88 K31 R67 K74 Q13485 ACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSP 5mf0 A 3.03 BS01 NUC E 1 R38 K46 T77 L78 L82 Q83 V84 A85 K88 R23 K31 T62 L63 L67 Q68 V69 A70 K73 Q13485 CLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 5mt6 A 2.16 BS01 III B 1 M120 F146 H150 F153 N154 Q189 S193 W196 F197 G198 G199 L200 S201 Y205 W236 F245 M247 S248 M249 A250 H254 M30 F56 H60 F63 N64 Q99 S103 W106 F107 G108 G109 L110 S111 Y115 W146 F155 M157 S158 M159 A160 H164 3.4.21.105 P09391 29107700 ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSL 5mt7 A 2.05 BS01 III B 1 M120 F146 H150 N154 Q189 S193 W196 F197 G198 G199 S201 S248 M249 A250 H254 M30 F56 H60 N64 Q99 S103 W106 F107 G108 G109 S111 S158 M159 A160 H164 3.4.21.105 P09391 29107700 ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSL 5mtf A 1.79 BS01 III C 1 M120 F146 H150 F153 N154 Q189 W196 F197 G198 G199 L200 S201 V204 W236 M247 S248 M249 A250 H254 M30 F56 H60 F63 N64 Q99 W106 F107 G108 G109 L110 S111 V114 W146 M157 S158 M159 A160 H164 3.4.21.105 B7MDQ0 29107700 ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLN 5mz3 A 2.15 BS01 8EN A 1 V38 A51 K53 E71 L74 L75 V83 I84 L104 T106 L108 M109 H148 L167 D168 F169 V35 A48 K50 E68 L71 L72 V80 I81 L101 T103 L105 M106 H145 L164 D165 F166 2.7.11.24 Q16539 29107542 ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDSELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPL 5n0j A 1.95 BS01 FAD A 1 G25 G26 G27 A28 G29 I47 E48 K49 G50 R51 G52 R53 S54 W56 M57 Q58 L60 W61 N62 G91 F92 V93 A127 T128 D132 G148 V153 C157 G288 D289 N295 Q296 V297 A300 G11 G12 G13 A14 G15 I33 E34 K35 G36 R37 G38 R39 S40 W42 M43 Q44 L46 W47 N48 G77 F78 V79 A109 T110 D114 G130 V135 C139 G270 D271 N277 Q278 V279 A282 Q7NCP4 QAQLYDVIIAGGGAGGLSAAVYLARYNLKVLVIEKGRGRSFWMQDLWNYVPRVVSGKELIEGGKEMALHYGADWLNGFVEAVTDTGEEFQVRVKYRFYPVFRAKYLIAATGLMDVLPQLENMQNVYEYAGYNLHVCLICDGYEMTNRRAALIAGSEKAINTAFVLNWFTPYITVLTLGAYPVGDEMRAKLADHGYPLIEKPIARFLGKDHVMDGIEFADGTSIKVDTGLISMGSIRHDGYLKNLDLLTDGGDIVTEYDCRTSHPRVFALGDLKKGLNQVSIAVADGTLAATAIWKEIRRA 5n0j A 1.95 BS02 FAD A 2 K49 W56 N90 F92 E94 K108 R110 F111 M131 D132 L134 Y144 A147 G148 V153 K35 W42 N76 F78 E80 K94 R96 F97 M113 D114 L116 Y126 A129 G130 V135 Q7NCP4 QAQLYDVIIAGGGAGGLSAAVYLARYNLKVLVIEKGRGRSFWMQDLWNYVPRVVSGKELIEGGKEMALHYGADWLNGFVEAVTDTGEEFQVRVKYRFYPVFRAKYLIAATGLMDVLPQLENMQNVYEYAGYNLHVCLICDGYEMTNRRAALIAGSEKAINTAFVLNWFTPYITVLTLGAYPVGDEMRAKLADHGYPLIEKPIARFLGKDHVMDGIEFADGTSIKVDTGLISMGSIRHDGYLKNLDLLTDGGDIVTEYDCRTSHPRVFALGDLKKGLNQVSIAVADGTLAATAIWKEIRRA 5n0j B 1.95 BS02 FAD B 2 K49 R51 W56 F92 K108 R110 F111 M131 D132 L134 Y144 A147 G148 V153 K38 R40 W45 F81 K97 R99 F100 M120 D121 L123 Y133 A136 G137 V142 Q7NCP4 DEKQAQLYDVIIAGGGAGGLSAAVYLARYNLKVLVIEKGRGRSFWMQDLWNYVPRVVSGKELIEGGKEMALHYGADWLNGFVEAVTDTGEEFQVRVKYRFKNSDYPVFRAKYLIAATGLMDVLPQLENMQNVYEYAGYNLHVCLICDGYEMTNRRAALIAGSEKAINTAFVLNWFTPYITVLTLGAYPVGDEMRAKLADHGYPLIEKPIARFLGKDHVMDGIEFADGTSIKVDTGLISMGSIRHDGYLKNLDLLTDGGDIVTEYDCRTSHPRVFALGDLKKGLNQVSIAVADGTLAATAIWKEIRRASAPRKWTAPLQEAAAR 5na6 A 1.90 BS01 ZN A 1 H448 H453 E476 H421 H426 E449 3.4.14.4 Q8A6N1 29095893 FDYTVEQFADLQILRYKVPEFETLTLKQKELVYYLTQAALEGRDILFDQNGKYNLRIRRMLEAVYTNYKGDKSAPDFKNMEVYLKRVWFSNGIHHHYGMEKFVPGFSQDFLKQAVLGTDAQLLPLSEGQTAEQLSDELFPVMFDPAILAKRVNQADGEDLVLTSASNYYDGVTQQEAESFYGAMKDPKDETPVSYGLNSRLVKIQEKVWKVGGLYTQAIEKIVYWLKKAETVAENDAQKAVISKLIQFYETGSLKDFDEYAILWVKDLDSRIDFVNGFTESYGDPLGVKASWESLVNFKDLDATHRTEIISSNAQWFEDHSPVDKSFKKEKVKGVSAKVITAAILAGDLYPATAIGINLPNANWIRAHHGSKSVTIGNITDAYNKAAHGNGFNEEFVSNDEERQRIDQYGDLTGELHTDLHESLGHGSGKLLPGVDPDALKAYGSTIEEARADLFGLYYVADPKLVELKLVPDAEAYKAEYYTFLMNGLMTQLVRIEPGNNIEEAHMRNRQLIARWVFEKGAPDKVVEMVKKDGKTYVVVNDYEKVRQLFGELLAEIQRIKSTGDFEGARTLVENYAVKVDPALHAEVLARYKKLNLAPYKGFINPVYELVTDKDGNITDVTVSYNEDYVEQMLRYSKDYSPLPSVNN 5na8 A 3.29 BS01 ZN A 1 H448 E449 H453 E476 H424 E425 H429 E452 3.4.14.4 Q8A6N1 29095893 DYTVEQFADLQILRYKVPEFETLTLKQKELVYYLTQAALEGRDILFDQNGKYNLRIRRMLEAVYTNYKGDKSAPDFKNMEVYLKRVWFSNGIHHHYGMEKFVPGFSQDFLKQAVLGTDAQLLPLSEGQTAEQLSDELFPVMFDPAILAKRVNQADGEDLVLTSASNYYDGVTQQEAESFYGAMKDPKDETPVSYGLNSRLVKEDGKIQEKVWKVGGLYTQAIEKIVYWLKKAETVAENDAQKAVISKLIQFYETGSLKDFDEYAILWVKDLDSRIDFVNGFTESYGDPLGVKASWESLVNFKDLDATHRTEIISSNAQWFEDHSPVDKSFKKEKVKGVSAKVITAAILAGDLYPATAIGINLPNANWIRAHHGSKSVTIGNITDAYNKAAHGNGFNEEFVSNDEERQRIDQYGDLTGELHTDLHESLGHGSGKLLPGVDPDALKAYGSTIEEARADLFGLYYVADPKLVELKLVPDAEAYKAEYYTFLMNGLMTQLVRIEPGNNIEEAHMRNRQLIARWVFEKGAPDKVVEMVKKDGKTYVVVNDYEKVRQLFGELLAEIQRIKSTGDFEGARTLVENYAVKVDPALHAEVLARYKKLNLAPYKGFINPVYELVTDKDGNITDVTVSYNEDYVEQMLRYSKDYSPLPSVNN 5nim A 1.50 BS01 8YE A 1 L87 W103 F110 F114 W138 M142 W145 T149 N176 N179 E180 L183 F184 W207 L67 W83 F90 F94 W118 M122 W125 T129 N156 N159 E160 L163 F164 W187 P9WMC1 SGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR 5nio A 1.40 BS01 8YH A 1 W103 G106 I107 F110 M142 Y148 T149 N176 N179 W207 W82 G85 I86 F89 M121 Y127 T128 N155 N158 W186 P9WMC1 GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGE 5nit A 1.87 BS01 FAD A 1 G26 G28 L29 V30 I49 E50 S51 Y68 F72 H78 R95 G97 N98 G99 G102 S103 N107 G108 G109 T110 Y249 V250 A288 A289 G290 V293 Y515 D548 G549 H559 V560 M561 F564 G24 G26 L27 V28 I47 E48 S49 Y66 F70 H76 R93 G95 N96 G97 G100 S101 N105 G106 G107 T108 Y247 V248 A286 A287 G288 V291 Y513 D546 G547 H557 V558 M559 F562 1.1.3.4 P13006 GIEASLLTDPKDVSGRTVDYIIAGGGLVGLTTAARLTENPNISVLVIESGSYESDRGPIIEDLNAYGDIFGSSVDHAYETVELATNNQTALVRSGNGLGGSTLVNGGTWTRPHKAQVDSWETVFGNEGWNWDNVAAYSLQAERARAPNAKQIAAGHYFNTSCHGVNGTVHAGPRDTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVSMFPNTLHEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVLLSQNGTTPRAVGVEFGTHKGNTHNVYAKHEVLLAAGSAVSPTILEYSGIGMKSILEPLGIDTVVDLPVGLNLQDQTTATVRSRITSAGAGQGQAAWFATFNETFGDYSEKAHELLNTKLEQWAEEAVARGGFHNTTALLIQYENYRDWIVNHNVAYSELFLDTAGVASFDVWDLLPFTRGYVHILDKDPYLHHFAYDPQYFLNELDLLGQAAATQLARNISNSGAMQTYFAGETIPGDNLAYDADLSAWTEYIPYHFRPNYHGVGTCSMMPKEMGGVVDNAAKVYGVQGLRVIDGSIPPTQVSSHVMTVFYAMALKISDAILEDYASMQ 5nit A 1.87 BS02 OXY A 1 H516 H559 V560 H514 H557 V558 1.1.3.4 P13006 GIEASLLTDPKDVSGRTVDYIIAGGGLVGLTTAARLTENPNISVLVIESGSYESDRGPIIEDLNAYGDIFGSSVDHAYETVELATNNQTALVRSGNGLGGSTLVNGGTWTRPHKAQVDSWETVFGNEGWNWDNVAAYSLQAERARAPNAKQIAAGHYFNTSCHGVNGTVHAGPRDTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVSMFPNTLHEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVLLSQNGTTPRAVGVEFGTHKGNTHNVYAKHEVLLAAGSAVSPTILEYSGIGMKSILEPLGIDTVVDLPVGLNLQDQTTATVRSRITSAGAGQGQAAWFATFNETFGDYSEKAHELLNTKLEQWAEEAVARGGFHNTTALLIQYENYRDWIVNHNVAYSELFLDTAGVASFDVWDLLPFTRGYVHILDKDPYLHHFAYDPQYFLNELDLLGQAAATQLARNISNSGAMQTYFAGETIPGDNLAYDADLSAWTEYIPYHFRPNYHGVGTCSMMPKEMGGVVDNAAKVYGVQGLRVIDGSIPPTQVSSHVMTVFYAMALKISDAILEDYASMQ 5nit A 1.87 BS03 NAG A 1 A86 T87 N89 A84 T85 N87 1.1.3.4 P13006 GIEASLLTDPKDVSGRTVDYIIAGGGLVGLTTAARLTENPNISVLVIESGSYESDRGPIIEDLNAYGDIFGSSVDHAYETVELATNNQTALVRSGNGLGGSTLVNGGTWTRPHKAQVDSWETVFGNEGWNWDNVAAYSLQAERARAPNAKQIAAGHYFNTSCHGVNGTVHAGPRDTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVSMFPNTLHEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVLLSQNGTTPRAVGVEFGTHKGNTHNVYAKHEVLLAAGSAVSPTILEYSGIGMKSILEPLGIDTVVDLPVGLNLQDQTTATVRSRITSAGAGQGQAAWFATFNETFGDYSEKAHELLNTKLEQWAEEAVARGGFHNTTALLIQYENYRDWIVNHNVAYSELFLDTAGVASFDVWDLLPFTRGYVHILDKDPYLHHFAYDPQYFLNELDLLGQAAATQLARNISNSGAMQTYFAGETIPGDNLAYDADLSAWTEYIPYHFRPNYHGVGTCSMMPKEMGGVVDNAAKVYGVQGLRVIDGSIPPTQVSSHVMTVFYAMALKISDAILEDYASMQ 5nit A 1.87 BS05 NAG A 3 N355 S362 E363 H366 N407 N353 S360 E361 H364 N405 1.1.3.4 P13006 GIEASLLTDPKDVSGRTVDYIIAGGGLVGLTTAARLTENPNISVLVIESGSYESDRGPIIEDLNAYGDIFGSSVDHAYETVELATNNQTALVRSGNGLGGSTLVNGGTWTRPHKAQVDSWETVFGNEGWNWDNVAAYSLQAERARAPNAKQIAAGHYFNTSCHGVNGTVHAGPRDTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVSMFPNTLHEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVLLSQNGTTPRAVGVEFGTHKGNTHNVYAKHEVLLAAGSAVSPTILEYSGIGMKSILEPLGIDTVVDLPVGLNLQDQTTATVRSRITSAGAGQGQAAWFATFNETFGDYSEKAHELLNTKLEQWAEEAVARGGFHNTTALLIQYENYRDWIVNHNVAYSELFLDTAGVASFDVWDLLPFTRGYVHILDKDPYLHHFAYDPQYFLNELDLLGQAAATQLARNISNSGAMQTYFAGETIPGDNLAYDADLSAWTEYIPYHFRPNYHGVGTCSMMPKEMGGVVDNAAKVYGVQGLRVIDGSIPPTQVSSHVMTVFYAMALKISDAILEDYASMQ 5niw A 1.80 BS04 NAG A 2 N258 R263 Q542 N256 R261 Q539 1.1.3.4 P13006 GIEASLLTDPKDVSGRTVDYIIAGGGLVGLTTAAKLTENPNISVLVIESGSYESDRGPIIEDLNAYGDIFGSSVDHAYETVELATNNQTALVRSGNGLGGSTLINGGTWTRPHKAQVDSWETVFGNEGWNWDNVAAYSLQAERARAPNAKQIAAGHYFNTSCHGVNGTVHAGPRDTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVSMFPNTLHEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVLLSQNGTTPRAVGVEFGTHKGNTHNVYAKHEVLLAAGSAVSPTILEYSGIGMKSILEPLGIDTVVDLPVGLNLQDQTTATVRSRITSAGAGQGQAAWFATFNETFGDYSEKAHELLNTKLQWAEEAVARGGFHNTTALLIQYENYRDWIVNHNVAYSELFLDTAGVASFDVWDLLPFTRGYVHILDKDPYLHHFAYDPQYFLNELDLLGQAAATQLARNISNSGAMQTYFAGETIPGDNLAYDADLSAWTEYIPYHFRPNYHGVGTCSMMPKEMGGVVDNAARVYGVQGLRVIDGSIPPTQVSSHVMTVFYAMALKISDAILEDYAS 5niw A 1.80 BS07 NAG A 5 N473 N476 Y496 N470 N473 Y493 1.1.3.4 P13006 GIEASLLTDPKDVSGRTVDYIIAGGGLVGLTTAAKLTENPNISVLVIESGSYESDRGPIIEDLNAYGDIFGSSVDHAYETVELATNNQTALVRSGNGLGGSTLINGGTWTRPHKAQVDSWETVFGNEGWNWDNVAAYSLQAERARAPNAKQIAAGHYFNTSCHGVNGTVHAGPRDTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVSMFPNTLHEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVLLSQNGTTPRAVGVEFGTHKGNTHNVYAKHEVLLAAGSAVSPTILEYSGIGMKSILEPLGIDTVVDLPVGLNLQDQTTATVRSRITSAGAGQGQAAWFATFNETFGDYSEKAHELLNTKLQWAEEAVARGGFHNTTALLIQYENYRDWIVNHNVAYSELFLDTAGVASFDVWDLLPFTRGYVHILDKDPYLHHFAYDPQYFLNELDLLGQAAATQLARNISNSGAMQTYFAGETIPGDNLAYDADLSAWTEYIPYHFRPNYHGVGTCSMMPKEMGGVVDNAARVYGVQGLRVIDGSIPPTQVSSHVMTVFYAMALKISDAILEDYAS 5niz A 1.95 BS01 8YT A 1 L87 W103 G106 I107 F110 F114 W138 M142 W145 Y148 T149 N176 N179 E180 W207 L65 W81 G84 I85 F88 F92 W116 M120 W123 Y126 T127 N154 N157 E158 W185 P9WMC1 DDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGE 5nj0 A 2.10 BS01 8YW A 1 M102 W103 G106 I107 F110 F114 W138 M142 W145 Y148 T149 V152 N176 N179 E180 L183 F184 W207 M80 W81 G84 I85 F88 F92 W116 M120 W123 Y126 T127 V130 N154 N157 E158 L161 F162 W185 P9WMC1 DDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGEN 5nj2 A 1.19 BS01 PO4 A 1 S70 S128 K236 T237 G238 T239 S41 S99 K207 T208 G209 T210 3.5.2.6 A0A0T9EA39 29087696 LADRFAELERRYDARLGVYVPATGTTAAIEYRADERFAFCSTFKAPLVAAVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATCVAGVLALEHHHHHH 5nm9 A 2.43 BS01 NUC C 1 R32 L72 L76 Q77 A79 K82 R24 L64 L68 Q69 A71 K74 B3S7S5 ATLGIVHTLMCHRQGGESENFAKRAVESLVKKLKDKRDELDALITAVTSNGIQQSKCVTIARTLDGRLQVAGKKGFPHVIYSRIWRWPDLHKNELKHIKLCKFAFDLKLDHVCVNPYHYERV 5nm9 A 2.43 BS02 NUC D 1 R75 Q77 K82 R67 Q69 K74 B3S7S5 ATLGIVHTLMCHRQGGESENFAKRAVESLVKKLKDKRDELDALITAVTSNGIQQSKCVTIARTLDGRLQVAGKKGFPHVIYSRIWRWPDLHKNELKHIKLCKFAFDLKLDHVCVNPYHYERV 5nm9 A 2.43 BS03 ZN A 1 C65 C109 C121 H126 C57 C101 C113 H118 B3S7S5 ATLGIVHTLMCHRQGGESENFAKRAVESLVKKLKDKRDELDALITAVTSNGIQQSKCVTIARTLDGRLQVAGKKGFPHVIYSRIWRWPDLHKNELKHIKLCKFAFDLKLDHVCVNPYHYERV 5nme A 2.94 BS01 III C 1 M5 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 L81 Y84 R97 Y99 K146 W147 Q155 L156 Y159 W167 Y171 M5 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 L81 Y84 R97 Y99 K146 W147 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nme D 2.94 BS01 III C 1 Q31 R92 T93 N94 G96 Y97 Q30 R91 T92 N93 G95 Y96 KEVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMFIYSNGDKEDGRFTAQLNKASQYISLLIRDSKLSDSATYLCAVRTNSGYALNFGKGTSLLVTPHIQKPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSP 5nme E 2.94 BS01 III C 1 T96 V97 Y99 T96 V97 Y99 DAGVTQSPTHLIKTRGQQVTLRCSPKQGHDTVSWYQQALGQGPQFIFQYYEEEERQRGNFPDRFSGHQFPNYSSELNVNALLLGDSALYLCASSDTVSYEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 5nme F 2.94 BS01 III H 1 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 L81 Y84 R97 Y99 Y116 Y123 T143 K146 W147 Q155 L156 Y159 W167 Y171 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 L81 Y84 R97 Y99 Y116 Y123 T143 K146 W147 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nme J 2.94 BS01 III H 1 T96 Y99 T96 Y99 DAGVTQSPTHLIKTRGQQVTLRCSPKQGHDTVSWYQQALGQGPQFIFQYYEEEERQRGNFPDRFSGHQFPNYSSELNVNALLLGDSALYLCASSDTVSYEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRA 5nmf A 2.89 BS01 III C 1 M5 Y7 F9 M45 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 Y116 Y123 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 F9 M45 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 Y116 Y123 K146 W147 V152 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nmf F 2.89 BS01 III H 1 M5 Y7 E63 K66 H70 T73 V76 D77 L81 R97 Y99 Y116 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 E63 K66 H70 T73 V76 D77 L81 R97 Y99 Y116 K146 W147 V152 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nmg F 2.75 BS01 III H 1 M5 Y7 F9 E63 K66 V67 A69 H70 T73 V76 D77 T80 L81 R97 Y99 Y116 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 M5 Y7 F9 E63 K66 V67 A69 H70 T73 V76 D77 T80 L81 R97 Y99 Y116 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nmh A 1.55 BS01 III C 1 Y7 F9 M45 E63 R65 K66 V67 H70 T73 V76 D77 L81 R97 Y99 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 Y7 F9 M45 E63 R65 K66 V67 H70 T73 V76 D77 L81 R97 Y99 Y123 T143 K146 W147 V152 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nmk A 1.66 BS01 III C 1 M5 Y7 F9 M45 E63 R65 K66 V67 H70 T73 D77 L81 R97 Y99 Y116 K146 W147 Q155 L156 Y159 W167 Y171 M5 Y7 F9 M45 E63 R65 K66 V67 H70 T73 D77 L81 R97 Y99 Y116 K146 W147 Q155 L156 Y159 W167 Y171 P01892 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP 5nvi A 1.60 BS01 HEM A 1 L38 L41 F42 Y44 H64 K67 V68 V71 Y88 L92 H96 V101 F106 L36 L39 F40 Y42 H62 K65 V66 V69 Y86 L90 H94 V99 F104 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5nvi A 1.60 BS02 AR A 1 I72 L136 Y137 I70 L134 Y135 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5nw6 A 1.70 BS02 KR A 1 F28 A29 F32 S55 L56 F26 A27 F30 S53 L54 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5o17 A 1.80 BS04 KR A 3 L27 V68 I72 V109 L113 Y137 L25 V66 I70 V107 L111 Y135 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5o17 A 1.80 BS05 KR A 4 G110 L113 L114 W133 S134 Y137 G108 L111 L112 W131 S132 Y135 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG 5o18 A 1.86 BS01 HEM A 1 L41 F42 Y44 H64 K67 V68 V71 Y88 L92 K95 H96 V99 V101 F106 V109 W140 L39 F40 Y42 H62 K65 V66 V69 Y86 L90 K93 H94 V97 V99 F104 V107 W138 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o1k A 2.05 BS03 XE A 2 A75 L136 Y137 W140 A73 L134 Y135 W138 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o1k A 2.05 BS04 XE A 3 I72 V109 Y137 I70 V107 Y135 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o1k A 2.05 BS06 XE A 5 P20 M69 L70 D73 P18 M67 L68 D71 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o27 A 2.31 BS01 HEM A 1 F42 Y44 H64 K67 V68 V71 L92 K95 H96 V99 V109 W140 F40 Y42 H62 K65 V66 V69 L90 K93 H94 V97 V107 W138 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o27 A 2.31 BS03 XE A 2 I72 V109 L113 Y137 I70 V107 L111 Y135 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o27 A 2.31 BS06 XE A 5 P20 R66 L70 P18 R64 L68 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o27 A 2.31 BS07 XE A 6 H96 V101 F106 M144 H94 V99 F104 M142 Q9ER97 29108649 RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAWVQAMSRGWDG 5o8z A 2.10 BS01 BEF A 1 D56 L57 S58 T87 M88 K109 D56 L57 S58 T87 M88 K109 P58663 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGPESVSRLLEKISARLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTL 5o8z A 2.10 BS02 MG A 1 D11 D56 S58 D11 D56 S58 P58663 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGPESVSRLLEKISARLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTL 5od6 A 2.00 BS01 NUC C 1 R74 K81 H100 H101 R65 K72 H91 H92 P84022 MIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPV 5od6 A 2.00 BS02 NUC D 1 S70 L71 Q76 V77 S78 H79 K81 S61 L62 Q67 V68 S69 H70 K72 P84022 MIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPV 5ode A 2.20 BS02 FAD A 2 K46 W53 F89 K105 R107 F108 M128 D129 L131 Y141 A144 G145 V150 K48 W55 F91 K107 R109 F110 M130 D131 L133 Y143 A146 G147 V152 Q7NCP4 GSHMILKRHFDEKQAQLYDVIIAGGGAGGLSAAVYLARYNLKVLVIEKGRGRSFWMQDLWNYVPRVVSGKELIEGGKEMALHYGADWLNGFVEAVTDTGEEFQVRVKYRFKNSDYPVFRAKYLIAATGLMDVLPQLENMQNVYEYAGYNLHVCLICDGYEMTNRRAALIAGSEKAINTAFVLNWFTPYITVLTLGAYPVGDEMRAKLADHGYPLIEKPIARFLGKDHVMDGIEFADGTSIKVDTGLISMGSIRHDGYLLDLLTDGGDIVTEYDCRTSHPRVFALGDLKKGLNQVSIAVADGTLAATAIWKEIRRASAPRKWTAP 5ode B 2.20 BS02 FAD B 2 K46 R50 W53 N87 F89 E91 K105 R107 F108 M128 D129 L131 Y141 A144 G145 V150 K47 R51 W54 N88 F90 E92 K106 R108 F109 M129 D130 L132 Y142 A145 G146 V151 Q7NCP4 SHMILKRHFDEKQAQLYDVIIAGGGAGGLSAAVYLARYNLKVLVIEKGRGRSFWMQDLWNYVPRVVSGKELIEGGKEMALHYGADWLNGFVEAVTDTGEEFQVRVKYRFKNSDYPVFRAKYLIAATGLMDVLPQLENMQNVYEYAGYNLHVCLICDGYEMTNRRAALIAGSEKAINTAFVLNWFTPYITVLTLGAYPVGDEMRAKLADHGYPLIEKPIARFLGKDHVMDGIEFADGTSIKVDTGLISMGSIRHDGYLKNLDLTDGDIVTEYDCRTSHPRVFALGDLKKGLNQVSIAVADGTLAATAIWKEIRRASAPRKWTA 5odg A 2.12 BS01 NUC D 1 S70 L71 Q76 S78 K81 S61 L62 Q67 S69 K72 P84022 MIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVL 5omw A 2.60 BS01 NUC B 1 Y43 D80 G83 L84 V156 A167 N168 E169 Q190 T215 M219 N222 W223 A291 E292 A296 T297 R416 L417 R418 S423 R424 Q425 R426 F493 E532 H533 M536 L570 M617 S618 K619 F648 A649 P651 Q659 G665 R668 K711 R718 R719 N723 T724 A727 M730 N734 V803 Q805 K809 V810 R811 K813 L834 K837 Y838 K846 I848 V850 L854 N856 V858 Y43 D80 G83 L84 V156 A167 N168 E169 Q190 T215 M219 N222 W223 A291 E292 A296 T297 R416 L417 R418 S423 R424 Q425 R426 F493 E532 H533 M536 L570 M617 S618 K619 F648 A649 P651 Q659 G665 R668 K711 R718 R719 N723 T724 A727 M730 N734 V803 Q805 K809 V810 R811 K813 L834 K837 Y838 K846 I848 V850 L854 N856 V858 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5omw A 2.60 BS02 ZN A 1 C159 C176 T181 C159 C176 T181 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5omw A 2.60 BS03 LSS A 1 M40 L41 P42 Y43 H49 G51 H52 N55 Y56 D80 S496 G529 G530 E532 H533 H537 Q566 G567 M568 V569 M620 M40 L41 P42 Y43 H49 G51 H52 N55 Y56 D80 S496 G529 G530 E532 H533 H537 Q566 G567 M568 V569 M620 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5omw D 2.60 BS01 NUC E 1 Y43 D80 G83 L84 V156 V165 A167 N168 E169 Q190 T215 T218 M219 N222 W223 A291 E292 A293 T297 R416 R418 S423 R424 Q425 R426 T492 F493 E532 H533 M536 L570 M617 S618 K619 F648 A649 P651 M654 Q659 S661 G662 G665 R668 K711 R718 R719 N723 T724 A727 M730 E731 N734 V803 K809 V810 K813 K846 I848 V850 N856 Y43 D80 G83 L84 V156 V165 A167 N168 E169 Q190 T215 T218 M219 N222 W223 A291 E292 A293 T297 R416 R418 S423 R424 Q425 R426 T492 F493 E532 H533 M536 L570 M617 S618 K619 F648 A649 P651 M654 Q659 S661 G662 G665 R668 K711 R718 R719 N723 T724 A727 M730 E731 N734 V803 K809 V810 K813 K846 I848 V850 N856 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5omx H 2.32 BS01 NUC I 1 K31 K34 E35 S36 Y40 K2 K5 E6 S7 Y11 P02281 29113904 RKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5omx H 2.32 BS02 NUC J 1 R30 T32 S55 S56 R86 S87 T88 R1 T3 S26 S27 R57 S58 T59 P02281 29113904 RKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 5on2 A 3.10 BS01 NUC B 1 Y43 D80 G83 L84 V165 A167 N168 E169 Q190 T215 M219 N222 W223 A291 E292 A293 A296 T297 R416 R418 R424 Q425 R426 T492 F493 E532 H533 M536 L570 G616 M617 S618 K619 F648 A649 S650 P651 Q659 S661 G662 G665 R668 K711 R718 R719 N723 T724 A727 M730 E731 N734 V803 K809 V810 R811 K813 K837 Y838 K846 I848 V850 L854 N856 V858 Y45 D82 G85 L86 V167 A169 N170 E171 Q192 T217 M221 N224 W225 A293 E294 A295 A298 T299 R418 R420 R426 Q427 R428 T494 F495 E534 H535 M538 L572 G618 M619 S620 K621 F650 A651 S652 P653 Q661 S663 G664 G667 R670 K713 R720 R721 N725 T726 A729 M732 E733 N736 V805 K811 V812 R813 K815 K839 Y840 K848 I850 V852 L856 N858 V860 6.1.1.4 P07813 29111343 SHMQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5on2 A 3.10 BS04 VRT A 1 Y246 T247 T248 R249 V326 L327 Y330 V335 M336 A337 V338 H341 D342 R344 D345 Y248 T249 T250 R251 V328 L329 Y332 V337 M338 A339 V340 H343 D344 R346 D347 6.1.1.4 P07813 29111343 SHMQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5on2 D 3.10 BS01 NUC E 1 Y43 D80 G83 L84 P85 V165 A167 N168 E169 Q190 T215 T218 M219 N222 W223 E292 A293 T297 R416 L417 R418 R424 Q425 R426 F493 E532 H533 I535 M536 L570 G616 M617 S618 K619 F648 A649 S650 P651 M654 Q659 S661 G665 R668 K671 K675 K711 R718 R719 N723 T724 A727 M730 E731 N734 L801 V803 K809 V810 R811 K813 K846 I848 V850 L854 Y43 D80 G83 L84 P85 V165 A167 N168 E169 Q190 T215 T218 M219 N222 W223 E292 A293 T297 R416 L417 R418 R424 Q425 R426 F493 E532 H533 I535 M536 L570 G616 M617 S618 K619 F648 A649 S650 P651 M654 Q659 S661 G665 R668 K671 K675 K711 R718 R719 N723 T724 A727 M730 E731 N734 L801 V803 K809 V810 R811 K813 K846 I848 V850 L854 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5on2 D 3.10 BS04 VRT D 1 Y246 T247 T248 R249 V326 L327 Y330 V335 M336 V338 H341 R344 D345 Y246 T247 T248 R249 V326 L327 Y330 V335 M336 V338 H341 R344 D345 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5on3 A 3.10 BS01 NUC B 1 Y43 D80 G83 L84 V165 A167 N168 E169 Q190 T215 T218 M219 N222 W223 A291 E292 A296 R416 R418 S423 R424 Q425 R426 T492 F493 E532 H533 M536 M568 L570 M617 S618 K619 F648 A649 P651 M654 Q659 S661 G662 G665 R668 K675 K711 R718 R719 N723 T724 A727 M730 E731 N734 V803 K809 V810 R811 K813 K837 Y838 K846 I848 V850 N856 V858 Y43 D80 G83 L84 V165 A167 N168 E169 Q190 T215 T218 M219 N222 W223 A291 E292 A296 R416 R418 S423 R424 Q425 R426 T492 F493 E532 H533 M536 M568 L570 M617 S618 K619 F648 A649 P651 M654 Q659 S661 G662 G665 R668 K675 K711 R718 R719 N723 T724 A727 M730 E731 N734 V803 K809 V810 R811 K813 K837 Y838 K846 I848 V850 N856 V858 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5on3 A 3.10 BS04 9YN A 1 T247 T248 R249 V326 L327 Y330 V335 M336 A337 D345 T247 T248 R249 V326 L327 Y330 V335 M336 A337 D345 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5on3 D 3.10 BS02 9YN D 1 T248 R249 F325 V326 L327 Y330 G331 V335 M336 A337 H341 D345 T248 R249 F315 V316 L317 Y320 G321 V325 M326 A327 H331 D335 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDAFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5onh A 3.10 BS04 VRT A 1 Y246 T248 R249 L327 Y330 V335 M336 V338 H341 R344 D345 Y246 T248 R249 L327 Y330 V335 M336 V338 H341 R344 D345 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5onh D 3.10 BS01 NUC E 1 Y43 D80 G83 L84 A167 N168 E169 Q190 T215 T218 M219 N222 W223 E292 A293 T297 R416 L417 R418 S423 R424 Q425 R426 T492 F493 E532 H533 I535 M536 L570 G616 M617 S618 K619 K622 F648 A649 P651 M654 Q659 S661 G665 R668 K671 K675 K711 R718 R719 N723 T724 A727 M730 E731 N734 L801 V803 K809 V810 R811 K813 K846 I848 V850 K853 L854 N856 Y43 D80 G83 L84 A167 N168 E169 Q190 T215 T218 M219 N222 W223 E292 A293 T297 R416 L417 R418 S423 R424 Q425 R426 T492 F493 E532 H533 I535 M536 L570 G616 M617 S618 K619 K622 F648 A649 P651 M654 Q659 S661 G665 R668 K671 K675 K711 R718 R719 N723 T724 A727 M730 E731 N734 L801 V803 K809 V810 R811 K813 K846 I848 V850 K853 L854 N856 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5onh D 3.10 BS04 VRT D 1 Y246 T247 T248 R249 L327 Y330 V335 M336 H341 R344 D345 Y246 T247 T248 R249 L327 Y330 V335 M336 H341 R344 D345 6.1.1.4 P07813 29111343 MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG 5oo6 A 2.80 BS01 III C 1 Y461 H561 Y435 H513 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 A 2.80 BS02 III C 2 I609 R610 Q612 C616 M648 H651 E705 I561 R562 Q564 C568 M600 H603 E641 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 B 2.80 BS01 III C 1 F49 Y50 Q55 M71 L73 K77 K78 T79 A80 D107 F46 Y47 Q52 M68 L70 K74 K75 T76 A77 D104 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGK 5oo6 B 2.80 BS02 MGT B 1 Y20 Y43 F83 F85 R112 D114 W115 D116 R123 Y125 R127 Q133 V134 Y17 Y40 F80 F82 R109 D111 W112 D113 R120 Y122 R124 Q130 V131 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGK 5oo6 D 2.80 BS01 III F 1 Y461 S558 H561 Y435 S520 H523 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 E 2.80 BS01 III F 1 Y50 Q55 M71 L73 K77 K78 T79 A80 D107 Y47 Q52 M68 L70 K74 K75 T76 A77 D104 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGK 5oo6 E 2.80 BS02 MGT E 1 Y20 Y43 F83 R112 D114 W115 D116 R123 R127 Q133 V134 Y17 Y40 F80 R109 D111 W112 D113 R120 R124 Q130 V131 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGK 5oo6 G 2.80 BS01 III I 1 Y461 K557 S558 H561 Y435 K509 S510 H513 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 G 2.80 BS02 III I 2 I609 R610 Q612 C616 H651 E705 I561 R562 Q564 C568 H603 E645 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 J 2.80 BS02 III L 2 I609 R610 Q612 C616 M648 H651 I561 R562 Q564 C568 M600 H603 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 M 2.80 BS02 III O 2 I609 R610 C616 M648 H651 E705 I571 R572 C578 M610 H613 E655 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oo6 Q 2.80 BS01 III R 1 F49 Y50 Q55 M71 L73 K78 T79 A80 D107 F46 Y47 Q52 M68 L70 K75 T76 A77 D104 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGK 5oo6 S 2.80 BS02 III U 2 H570 I609 R610 Q612 C616 M648 H651 H522 I561 R562 Q564 C568 M600 H603 Q09161 29101316 TEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPVNPTCIYKGHSVALCLAVAFKSKATNDEIFSILKDVPNPNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oob A 2.79 BS01 III Z 1 Y461 K511 K557 S560 H561 K568 Y436 K486 K524 S527 H528 K535 Q09161 29101316 ETEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNEGFSFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oob A 2.79 BS02 III Z 2 I609 R610 Q612 C616 H651 I576 R577 Q579 C583 H618 Q09161 29101316 ETEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNEGFSFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oob B 2.79 BS01 III Z 1 Y50 E53 Q55 M71 L73 K78 T79 A80 D107 Y47 E50 Q52 M68 L70 K75 T76 A77 D104 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQN 5oob B 2.79 BS02 MGT B 1 Y20 D22 Y43 F83 D114 W115 D116 R123 G126 R127 Q133 V134 R135 Y17 D19 Y40 F80 D111 W112 D113 R120 G123 R124 Q130 V131 R132 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQN 5oob C 2.79 BS01 III E 1 Y461 S558 S560 H561 S564 Y439 S523 S525 H526 S529 Q09161 29101316 DANETEDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPFNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oob D 2.79 BS01 III E 1 Y50 E53 Q55 K68 I69 I70 M71 L73 K78 T79 A80 D107 E121 Y47 E50 Q52 K65 I66 I67 M68 L70 K75 T76 A77 D104 E118 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQ 5oob D 2.79 BS02 MGT D 1 Y20 D22 Y43 F83 F85 D114 W115 D116 R123 R127 Q133 V134 Y17 D19 Y40 F80 F82 D111 W112 D113 R120 R124 Q130 V131 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQ 5oob I 2.79 BS01 III K 1 Y461 K511 S560 H561 S564 Y434 K484 S520 H521 S524 Q09161 29101316 EDHLESLICKVGEKSACSLESNLEGLAGVLEADLPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANNYNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWVGKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLKKDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEGPVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELFQLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHHLSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPANPTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNNPLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILAVFQQFCALQA 5oob J 2.79 BS01 III K 1 F49 Y50 E53 Q55 I70 M71 L73 K78 T79 A80 E121 F46 Y47 E50 Q52 I67 M68 L70 K75 T76 A77 E118 P52298 29101316 GLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGK 5orf A 2.54 BS01 PRO A 1 A576 Q579 A580 A576 Q579 A580 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf A 2.54 BS02 PRO A 2 P303 A306 P303 A306 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf B 2.54 BS01 PRO B 1 F501 D502 F501 D502 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf B 2.54 BS02 PRO B 2 N300 L301 P302 P303 N300 L301 P302 P303 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf C 2.54 BS01 PRO C 1 N18 N158 V282 L283 N18 N158 V282 L283 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf C 2.54 BS02 PRO C 2 E118 P119 D120 E171 D172 K173 G174 E118 P119 D120 E171 D172 K173 G174 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf C 2.54 BS03 PRO C 3 E564 V568 E564 V568 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf D 2.54 BS01 PRO D 1 N300 L301 P302 N300 L301 P302 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5orf D 2.54 BS02 PRO D 2 A405 V408 R409 R412 D540 A405 V408 R409 R412 D540 P14639 29095162 DTHKSEIAHRFNDLGEENFQGLVLIAFSQYLQQCPFDEHVKLVKELTEFAKTCVADESHAGCDKSLHTLFGDELCKVATLRETYGDMADCCEKQEPERNECFLNHKDDSPDLPKLKPEPDTLCAEFKADEKKFWGKYLYEVARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIDAMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKADFTDVTKIVTDLTKVHKECCHGDLLECADDRADLAKYICDHQDALSSKLKECCDKPVLEKSHCIAEVDKDAVPENLPPLTADFAEDKEVCKNYQEAKDVFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEDCCAKEDPHACYATVFDKLKHLVDEPQNLIKKNCELFEKHGEYGFQNALIVRYTRKAPQVSTPTLVEISRSLGKVGTKCCAKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSDLTLDETYVPKPFDEKFFTFHADICTLPDTEKQIKKQTALVELLKHKPKATDEQLKTVMENFVAFVDKCCAADDKEGCFVLEGPKLVASTQAALA 5osg h 2.90 BS01 NUC 2 1 N55 Y58 R86 R87 F94 S98 A99 A100 V101 K102 I105 P122 A123 K124 A125 D130 F139 P142 F144 R145 P146 S147 T148 T149 K150 Q152 M154 R164 R166 M167 Y168 R169 Q170 N171 F172 Y174 R196 H198 R201 L204 S205 A206 R207 K211 L212 R215 Q216 A219 V222 I223 N1 Y4 R32 R33 F40 S44 A45 A46 V47 K48 I51 P68 A69 K70 A71 D76 F85 P88 F90 R91 P92 S93 T94 T95 K96 Q98 M100 R110 R112 M113 Y114 R115 Q116 N117 F118 Y120 R142 H144 R147 L150 S151 A152 R153 K157 L158 R161 Q162 A165 V168 I169 E9BNI3 29107485 NGVYVKNWGTGSVADATNVFSAAGKVVKVQLRRQRYALVFFENSAAVKKAIDLFNEKEVLGQTVLVVPAKASPKPDAHENSSCVFVSPIFRPSTTKAQVMELFAGVKVQRLRMYRQNFAYAYLDSPAAAKKFVEEKNGTAFRGHTLRVALSARSLEKLRARQEVANVVIAAHR 5osg P 2.90 BS01 NUC 2 1 A217 R220 R221 R224 Q225 R226 H228 S229 K230 R234 V236 R240 A1 R4 R5 R8 Q9 R10 H12 S13 K14 R18 V20 R24 Q9NE83 29107485 ASNRRALRQRDHSKKHTRKVHAQRAEVAAFQKK 5tvh A 2.40 BS01 7KO A 1 W147 V148 Y188 C190 C191 Y195 W153 V154 Y194 C196 C197 Y201 Q8WSF8 DDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5tvh B 2.40 BS02 7KO C 1 T36 Y55 V108 M116 I118 T37 Y56 V109 M117 I119 Q8WSF8 LHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5tvh C 2.40 BS01 7KO C 1 W147 V148 Y188 C191 W150 V151 Y191 C194 Q8WSF8 DKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5tvh D 2.40 BS02 7KO E 1 T36 V108 M116 I118 T45 V117 M125 I127 Q8WSF8 DYKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 5tvt A 2.28 BS01 7LV A 1 I17 V25 A38 K40 E57 L61 C70 L86 E87 Y88 C89 L139 I149 D150 I18 V26 A39 K41 E58 L62 C71 L87 E88 Y89 C90 L140 I150 D151 2.7.11.1,2.7.10.2 Q14680 GSKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 5tyi C 2.15 BS01 III L 1 K476 K478 K51 K53 Q14451 HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRV 5tyi D 2.15 BS01 III P 1 R438 S460 R462 N463 V468 K478 H479 Y480 L481 M495 D496 D497 R14 S36 R38 N39 V44 K54 H55 Y56 L57 M70 D71 D72 Q14451 IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCC 5u06 A 2.10 BS01 III L 1 R438 R458 S460 R462 V468 K478 H479 Y480 L481 L483 M495 D496 D497 R13 R33 S35 R37 V43 K53 H54 Y55 L56 L58 M70 D71 D72 Q14451 HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL 5u06 D 2.10 BS01 III P 1 R438 R458 S460 R462 V468 K478 H479 Y480 L481 M495 D496 Q499 R14 R34 S36 R38 V44 K54 H55 Y56 L57 M69 D70 Q73 Q14451 IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEERLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTR 5u1q B 2.10 BS01 III M 1 R438 K478 H479 Y480 L481 L483 M495 D496 Q499 I518 R17 K57 H58 Y59 L60 L62 M74 D75 Q78 I97 Q14451 SAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCT 5u1q C 2.10 BS01 III N 1 R438 K478 H479 Y480 L481 L483 M495 D496 D497 Q499 R16 K56 H57 Y58 L59 L61 M72 D73 D74 Q76 Q14451 AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCT 5u1q D 2.10 BS01 III P 1 R438 S460 R462 N463 V468 K478 H479 Y480 L481 L483 M495 D496 D497 Q499 R10 S32 R34 N35 V40 K50 H51 Y52 L53 L55 M67 D68 D69 Q71 Q14451 QLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTR 5u32 A 2.19 BS01 GDP A 1 G422 C423 G424 K425 T426 T427 R528 D583 K588 S589 S590 L626 G16 C17 G18 K19 T20 T21 R122 D166 K171 S172 S173 L209 6.5.1.3 LSTTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSSKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 5u32 A 2.19 BS02 MG A 1 T426 D445 T20 D39 6.5.1.3 LSTTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSSKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 5ugi A 1.80 BS01 EQU A 1 Y14 S58 L63 F82 V84 F86 V95 D99 M112 A114 F116 Y13 S57 L62 F81 V83 F85 V94 D98 M111 A113 F115 5.3.3.1 P00947 28719738 NTPEHMTAVVQRYVAALNAGDLDGIVALFADDATVEGPVGSEPRSGTAAIREAYANSLKLPLAVELTQEVRAVANEAAFAFTVSFEYQGRKTVVAPIDHFRFNGAGKVVSMRALFGEKNIHAGA 5veu A 2.91 BS01 HEM A 1 R105 I118 S119 W126 R130 I184 I301 F302 A305 G306 T309 V313 V369 A370 L373 R375 P433 F434 G435 R439 C441 I442 F446 A447 M451 R79 I92 S93 W100 R104 I158 I268 F269 A272 G273 T276 V280 V336 A337 L340 R342 P400 F401 G402 R406 C408 I409 F413 A414 M418 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu A 2.91 BS02 RIT A 1 R106 L120 F210 F213 F215 F220 F241 I301 F304 A305 T309 A370 G480 R80 L94 F184 F187 F189 F194 F215 I268 F271 A272 T276 A337 G447 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu B 2.91 BS01 HEM B 1 R105 I118 W126 R130 F302 A305 G306 T309 V369 A370 L373 R375 P433 F434 R439 N440 C441 I442 A447 M451 R79 I92 W100 R104 F269 A272 G273 T276 V336 A337 L340 R342 P396 F397 R402 N403 C404 I405 A410 M414 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu B 2.91 BS02 RIT B 1 R106 L120 F210 F215 F241 I301 F304 A305 T309 A370 I371 E374 G480 R80 L94 F184 F189 F215 I268 F271 A272 T276 A337 I338 E341 G443 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu D 2.91 BS01 HEM D 1 R105 I118 S119 W126 R130 F137 I184 F302 A305 G306 T309 V313 A370 L373 R375 P433 F434 R439 C441 I442 F446 A447 R79 I92 S93 W100 R104 F111 I158 F269 A272 G273 T276 V280 A337 L340 R342 P397 F398 R403 C405 I406 F410 A411 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu E 2.91 BS01 HEM E 1 R105 I118 W126 R130 I184 F302 A305 G306 T309 V313 L364 A370 L373 R375 P433 F434 G435 R439 C441 I442 A447 M451 R79 I92 W100 R104 I155 F258 A261 G262 T265 V269 L320 A326 L329 R331 P384 F385 G386 R390 C392 I393 A398 M402 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNLDFLQLMIDSQALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVL 5veu H 2.91 BS01 HEM H 1 R105 I118 W126 R130 F302 A305 G306 T309 V369 A370 L373 R375 P433 F434 G435 R439 C441 I442 A447 M451 R79 I92 W100 R104 F269 A272 G273 T276 V336 A337 L340 R342 P397 F398 G399 R403 C405 I406 A411 M415 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu H 2.91 BS02 RIT H 1 R105 R106 L120 F210 F213 G214 F220 L240 F241 I301 F304 A305 T309 E374 G480 L481 R79 R80 L94 F184 F187 G188 F194 L214 F215 I268 F271 A272 T276 E341 G444 L445 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu I 2.91 BS01 HEM I 1 R105 I118 W126 R130 I184 F302 A305 G306 T309 V313 V369 A370 L373 R375 P433 F434 R439 N440 C441 I442 F446 A447 M451 R79 I92 W100 R104 I158 F276 A279 G280 T283 V287 V343 A344 L347 R349 P402 F403 R408 N409 C410 I411 F415 A416 M420 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu J 2.91 BS01 HEM J 1 R105 I118 S119 W126 R130 F137 F302 A305 G306 T309 V313 A370 L373 R375 P433 F434 G435 R439 N440 C441 I442 F446 A447 M451 R79 I92 S93 W100 R104 F111 F269 A272 G273 T276 V280 A337 L340 R342 P396 F397 G398 R402 N403 C404 I405 F409 A410 M414 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 5veu L 2.91 BS01 HEM L 1 R105 I118 S119 W126 R130 F137 I184 F302 A305 G306 T309 V369 A370 L373 R375 P433 F434 R439 N440 C441 I442 A447 M451 R79 I92 S93 W100 R104 F111 I158 F261 A264 G265 T268 V328 A329 L332 R334 P387 F388 R393 N394 C395 I396 A401 M405 1.14.14.1 P20815 29093019 TRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNFLQLMIDSQNSALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDS 5vkg A BS01 4N1 A 1 D40 S41 T56 C73 W75 K90 D39 S40 T55 C72 W74 K89 Q99816 AVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP 5vmm A 3.60 BS01 HEM A 1 F43 F46 H58 K61 A88 H89 L91 F43 F46 H58 K61 A86 H87 L89 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 5vmm C 3.60 BS01 HEM C 1 F43 H58 K61 A65 A88 H89 L91 F98 F43 H58 K61 A65 A88 H89 L91 F98 P69905 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 5vmm E 3.60 BS01 HEM C 1 E354 S361 M362 M363 Y444 E230 S237 M238 M239 Y320 A0A1K8PKR3 SNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKENGEQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEA 5vmm F 3.60 BS01 HEM A 1 S361 M362 I438 Y444 S232 M233 I309 Y315 A0A1K8PKR3 QELREAIKNPAIKDKDHSAPNSRPIDFEMKKENGEQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAF 5vr7 A 2.61 BS01 A1F A 1 K64 F66 V67 R83 A93 S96 E98 V114 H119 L121 Y124 F165 V169 K52 F54 V55 R71 A81 S84 E86 V102 H107 L109 Y112 F153 V157 O80992 29084945 SEQKTLEPVIKTYHQFEPDPTTCTSLITQRIHAPASVVWPLIRRFDNPERYKHFVKRCRLISGDGDVGSVREVTVISGLPASTSTERLEFVDDDHRVLSFRVVGGEHRLKNYKSVTSVNEFLNQDSGKVYTVVLESYTVDIPEGNTEEDTKMFVDTVVKLNLQKLGVAATSAPMHD 5vr7 B 2.61 BS02 MG B 2 R199 E203 D204 D243 G244 N493 R14 E18 D19 D47 G48 N297 3.1.3.16 Q9CAJ0 29084945 CIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLTHLTGHFFGVYDGHGGHKVADYCRDRLHFALAEEIERIKDELCKRNTGEGRQVQWDKVFTSCFLTVDGEIEGKIGRAVVGSSDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEAMPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKPYVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKKNGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQRK 5vs5 A 2.80 BS01 9J7 A 1 K64 F66 V67 R83 L91 A93 S96 E98 H119 L121 Y124 F165 V169 N173 K52 F54 V55 R71 L79 A81 S84 E86 H107 L109 Y112 F153 V157 N161 O80992 29084945 SEQKTLEPVIKTYHQFEPDPTTCTSLITQRIHAPASVVWPLIRRFDNPERYKHFVKRCRLISGDGDVGSVREVTVISGLPASTSTERLEFVDDDHRVLSFRVVGGEHRLKNYKSVTSVNEFLNQDSGKVYTVVLESYTVDIPEGNTEEDTKMFVDTVVKLNLQKLGVAATSAPMHD 5vsr A 2.62 BS01 AF0 A 1 K64 V67 R83 L91 A93 S96 E98 F112 V114 H119 L121 Y124 F165 V169 N173 K52 V55 R71 L79 A81 S84 E86 F100 V102 H107 L109 Y112 F153 V157 N161 O80992 29084945 SEQKTLEPVIKTYHQFEPDPTTCTSLITQRIHAPASVVWPLIRRFDNPERYKHFVKRCRLISGDGDVGSVREVTVISGLPASTSTERLEFVDDDHRVLSFRVVGGEHRLKNYKSVTSVNEFLNQDSGKVYTVVLESYTVDIPEGNTEEDTKMFVDTVVKLNLQKLGVAATSAPMH 5vsr B 2.62 BS01 MG B 1 D243 G244 D492 D49 G50 D291 3.1.3.16 Q9CAJ0 29084945 LDCIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLTHLTGHFFGVYDGHGGHKVADYCRDRLHFALAEEIERIKDELGRQVQWDKVFTSCFLTVDGEIEGKIGRAVVGSSDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEAMPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKPYVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKKNGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQRKF 5vt7 B 2.62 BS02 MG B 2 R199 D204 D243 D492 N493 R17 D22 D50 D291 N292 3.1.3.16 Q9CAJ0 29084945 ELDCIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLTHLTGHFFGVYDGHGGHKVADYCRDRLHFALAEEIERIKDEGRQVQWDKVFTSCFLTVDGEIEGKIGRAVVGSSDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEAMPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKPYVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKKNGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQRKF 5vt7 B 2.62 BS03 MG B 3 D204 D243 S431 D432 G433 D492 N493 D22 D50 S230 D231 G232 D291 N292 3.1.3.16 Q9CAJ0 29084945 ELDCIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLTHLTGHFFGVYDGHGGHKVADYCRDRLHFALAEEIERIKDEGRQVQWDKVFTSCFLTVDGEIEGKIGRAVVGSSDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEAMPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKPYVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKKNGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQRKF 5vwv A 1.90 BS01 III B 1 I81 Y89 E92 F93 M96 H99 L100 Y110 K113 I114 S117 L118 E120 N124 W125 G126 R127 A130 F134 I65 Y73 E76 F77 M80 H83 L84 Y94 K97 I98 S101 L102 E104 N108 W109 G110 R111 A114 F118 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGNG 5vwv A 1.90 BS02 TFA A 1 R42 N86 F93 G133 R137 R26 N70 F77 G117 R121 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGNG 5vww A 2.80 BS01 III C 1 I81 I85 R88 Y89 E92 F93 M96 H99 L100 Y110 I114 S117 L118 S121 N124 W125 G126 R127 A130 F134 I47 I51 R54 Y55 E58 F59 M62 H65 L66 Y76 I80 S83 L84 S87 N90 W91 G92 R93 A96 F100 Q16611 LGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAAL 5vww B 2.80 BS01 III C 1 N182 L183 G184 N185 N139 L140 G141 N142 Q16611 SEEQVAQDTEEVFRSYVFYRHQQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vww B 2.80 BS02 III D 1 I81 I85 Y89 E92 F93 M96 L100 Y110 I114 S117 L118 S121 N124 R127 F134 I38 I42 Y46 E49 F50 M53 L57 Y67 I71 S74 L75 S78 N81 R84 F91 Q16611 SEEQVAQDTEEVFRSYVFYRHQQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vwx A 2.49 BS01 III B 1 R42 I81 I85 N86 R88 Y89 E92 F93 M96 L97 K113 I114 S117 L118 S121 N124 W125 G126 R127 V129 A130 R137 R21 I44 I48 N49 R51 Y52 E55 F56 M59 L60 K76 I77 S80 L81 S84 N87 W88 G89 R90 V92 A93 R100 Q16611 MSEEQVAQDTEEVFRSYVFYRHQQEQELQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vwx C 2.49 BS01 III B 1 L183 G184 L147 G148 Q16611 MSEEQVAQDTEEVFRSYVFYRHQQEQEALQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLG 5vwx C 2.49 BS02 III D 1 R42 I81 I85 N86 R88 Y89 E92 F93 M96 H99 Y110 K113 I114 S117 L118 E120 S121 N124 W125 G126 R127 V129 A130 G133 R137 R21 I45 I49 N50 R52 Y53 E56 F57 M60 H63 Y74 K77 I78 S81 L82 E84 S85 N88 W89 G90 R91 V93 A94 G97 R101 Q16611 MSEEQVAQDTEEVFRSYVFYRHQQEQEALQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLG 5vwy A 1.56 BS01 III B 1 R42 I81 G82 I85 N86 R88 Y89 E92 F93 M96 L100 I114 S117 L118 E120 S121 N124 W125 G126 R127 V129 A130 G133 F134 R137 R20 I48 G49 I52 N53 R55 Y56 E59 F60 M63 L67 I81 S84 L85 E87 S88 N91 W92 G93 R94 V96 A97 G100 F101 R104 Q16611 SEEQVAQDTEEVFRSYVFYRHQQEQEDPEMVTQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGNG 5vwz A 1.62 BS01 III B 1 R42 I81 G82 I85 N86 R88 Y89 E92 F93 T95 M96 H99 Y110 I114 S117 L118 E120 S121 N124 G126 R127 V129 A130 G133 F134 R137 G184 N185 R22 I61 G62 I65 N66 R68 Y69 E72 F73 T75 M76 H79 Y90 I94 S97 L98 E100 S101 N104 G106 R107 V109 A110 G113 F114 R117 G164 N165 Q16611 SMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGNG 5vwz A 1.62 BS02 III D 1 G51 S91 Q94 T95 G31 S71 Q74 T75 Q16611 SMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGNG 5vwz C 1.62 BS01 III B 1 E50 G51 A53 T95 E30 G31 A33 T75 Q16611 SMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLG 5vwz C 1.62 BS02 III D 1 R42 I81 G82 I85 N86 R88 Y89 E92 F93 M96 L100 Y110 I114 S117 L118 E120 S121 N124 G126 R127 A130 G133 F134 R137 L183 G184 R22 I61 G62 I65 N66 R68 Y69 E72 F73 M76 L80 Y90 I94 S97 L98 E100 S101 N104 G106 R107 A110 G113 F114 R117 L163 G164 Q16611 SMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLG 5vx0 A 1.60 BS01 III B 1 R42 I81 I85 N86 R88 Y89 E92 F93 M96 H99 L100 I114 S117 L118 S121 N124 W125 G126 R127 A130 F134 R137 L183 G184 N185 R26 I65 I69 N70 R72 Y73 E76 F77 M80 H83 L84 I98 S101 L102 S105 N108 W109 G110 R111 A114 F118 R121 L167 G168 N169 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vx0 A 1.60 BS02 MG A 1 M22 V27 D30 G176 W177 M6 V11 D14 G160 W161 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vx0 A 1.60 BS03 MG A 2 T103 A104 T87 A88 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vx0 A 1.60 BS04 MG A 3 N124 W125 W170 N108 W109 W154 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vx0 A 1.60 BS05 MG A 4 Q73 R76 Q57 R60 Q16611 GPLGSMSEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLGN 5vx2 A 1.85 BS01 III B 1 V216 H224 A227 F228 M231 L235 S245 R248 V249 H252 V253 S255 D256 N260 W261 G262 R263 V265 T266 L267 F318 F319 V45 H53 A56 F57 M60 L64 S74 R77 V78 H81 V82 S84 D85 N89 W90 G91 R92 V94 T95 L96 F147 F148 Q07820 DDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVE 5vx2 A 1.85 BS02 III D 1 R222 N223 H224 E225 T226 A227 R51 N52 H53 E54 T55 A56 Q07820 DDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVE 5vx3 A 1.95 BS01 III B 1 A93 F97 R100 Y101 A104 F105 L108 T109 Q111 L112 S122 Q125 V126 E129 L130 N136 W137 G138 R139 F146 Y195 A37 F41 R44 Y45 A48 F49 L52 T53 Q55 L56 S66 Q69 V70 E73 L74 N80 W81 G82 R83 F90 Y139 Q07817 MSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 5vx3 C 1.95 BS01 III D 1 A93 E96 F97 R100 Y101 A104 F105 L108 Q111 L112 S122 Q125 V126 E129 L130 N136 W137 G138 R139 V141 A142 L194 Y195 A38 E41 F42 R45 Y46 A49 F50 L53 Q56 L57 S67 Q70 V71 E74 L75 N81 W82 G83 R84 V86 A87 L139 Y140 Q07817 SMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 5vx3 E 1.95 BS01 III F 1 A93 F97 Y101 R103 A104 Q111 L112 S122 Q125 V126 E129 L130 R132 D133 N136 W137 G138 R139 V141 F146 L194 Y195 A42 F46 Y50 R52 A53 Q60 L61 S71 Q74 V75 E78 L79 R81 D82 N85 W86 G87 R88 V90 F95 L143 Y144 Q07817 GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN 5w4l A 2.92 BS01 III M 1 A281 S365 G366 G367 D368 E370 I371 S375 F376 F382 N425 M426 W427 G429 T430 G473 A177 S239 G240 G241 D242 E244 I245 S249 F250 F256 N289 M290 W291 G293 T294 G337 A0A0M3KKW9 29056481 DNLWVTVYYGVPVWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGGDIRKAYCEINGTKWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLFNNTCIMKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE 5wdm A 2.80 BS01 III B 1 G8 S9 V12 Y16 G23 F24 F25 Y26 G5 S6 V9 Y13 G20 F21 F22 Y23 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm A 2.80 BS02 III C 1 G8 S9 H10 E13 G5 S6 H7 E10 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm A 2.80 BS03 III F 1 L6 E13 A14 Y16 L17 L3 E10 A11 Y13 L14 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm A 2.80 BS04 III F 2 L17 V18 E21 L49 E53 L14 V15 E18 L37 E41 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm B 2.80 BS03 III C 2 L17 V18 E21 L49 L14 V15 E18 L38 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTPGIVEQCCHSICSLEQLENYCN 5wdm C 2.80 BS01 III A 1 H5 H10 H1 H6 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm C 2.80 BS02 III B 1 H5 L6 H10 E13 A14 L17 V18 L49 L52 H1 L2 H6 E9 A10 L13 V14 L36 L39 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm C 2.80 BS03 III D 1 G8 S9 V12 Y16 E21 G23 F24 F25 Y26 G4 S5 V8 Y12 E17 G19 F20 F21 Y22 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm C 2.80 BS04 III F 1 H10 E13 H6 E9 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm D 2.80 BS01 III C 1 G8 S9 V12 Y16 G23 F24 F25 Y26 P28 G5 S6 V9 Y13 G20 F21 F22 Y23 P25 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTPRGIVEQCCHSICSLEQLENYCN 5wdm D 2.80 BS02 III E 1 Q4 L6 H10 A14 Y16 L17 Q1 L3 H7 A11 Y13 L14 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTPRGIVEQCCHSICSLEQLENYCN 5wdm E 2.80 BS01 III D 1 L6 H10 A14 Y16 L17 L3 H7 A11 Y13 L14 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTPRGIVEQCCHSICSLEQLENYCN 5wdm E 2.80 BS02 III F 1 G8 S9 V12 E13 Y16 G23 F24 F25 Y26 T27 N57 G5 S6 V9 E10 Y13 G20 F21 F22 Y23 T24 N47 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTPRGIVEQCCHSICSLEQLENYCN 5wdm E 2.80 BS03 III F 3 Y26 T27 Y23 T24 A6XGL2 QHLCGSHLVEALYLVCGERGFFYTPRGIVEQCCHSICSLEQLENYCN 5wdm F 2.80 BS02 III A 2 L17 V18 L49 E53 L13 V14 L36 E40 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm F 2.80 BS03 III B 1 H5 C7 H10 H1 C3 H6 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5wdm F 2.80 BS04 III C 1 S9 H10 E13 S5 H6 E9 A6XGL2 HLCGSHLVEALYLVCGERGFFYTGIVEQCCHSICSLEQLENYCN 5whg A 2.70 BS01 ZN A 1 C74 C77 H90 H96 C24 C27 H31 H37 Q04311 LKKNDLYIFDLSEQLLNSLKLMSCSVCQMSHYQTDYHLMNVKRNLRGSPYIYFKSKYVLAIYKSLFNKRSLSNPNEALTFWNSQENPMAISALFMVGGGHFAGAIVSHQRLNETLIEQAVNFLEHKTFHRYTSALKTDIQGVLKDWEPYLSKCDNIFIRARNVSDKKIFTDNTVLNKGDERIKSFPFTTNRPTVLELKKAWCELSYLKILPK 5wic B 2.55 BS01 FOA B 1 V118 Q119 Y122 F141 D148 V30 Q31 Y34 F53 D60 Q17U16 29097752 RDQTSYGDEIDKFWLTQYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVKINSVILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPLGFRVTSYRVNPE 5wic B 2.55 BS02 FOA B 2 H109 R110 S112 Y113 Y137 K140 L147 H21 R22 S24 Y25 Y49 K52 L59 Q17U16 29097752 RDQTSYGDEIDKFWLTQYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVKINSVILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPLGFRVTSYRVNPE 5wii A 2.79 BS01 AO4 A 1 H109 R110 E111 S112 Y113 Y137 K140 H20 R21 E22 S23 Y24 Y48 K51 Q17U16 29097752 DQTSYGDEIDKFWLTQYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVKINSVILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPLGFRVTSYRVNPE 5wio A 2.52 BS01 XXE A 1 I108 S112 Y113 D114 S117 D121 T156 T157 R158 I21 S25 Y26 D27 S30 D34 T69 T70 R71 Q17U16 29097752 TRDQTSYGDEIDKFWLTQYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVKINSVILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPLGFRVTSYRVNPE 5wip A 2.62 BS01 XXO A 1 H109 R110 E111 S112 Y113 V118 D121 Y137 K140 H22 R23 E24 S25 Y26 V31 D34 Y50 K53 Q17U16 29097752 TRDQTSYGDEIDKFWLTQYVIHRESYDFYSVQVDYTAVGLMSTPNVAESYQSKFKGRNGLDKVLGDSETTRVKINSVILDKPHGVATIRFTTVRRVRSNPVDDQPQRWIAIMGYEYKSLAMNAEQRYVNPLGFRVTSYRVNPE 5wkp A 3.15 BS01 PLP A 1 G126 A127 T128 H156 D232 A234 Q235 S255 H257 K258 G72 A73 T74 H102 D178 A180 Q181 S201 H203 K204 2.8.1.7 Q9Y697 29097656 SLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSALEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKWT 5wkp B 3.15 BS01 8Q1 C 1 V9 M16 A39 F40 N43 K44 V46 I52 L55 V5 M12 A35 F36 N39 K40 V42 I48 L51 Q9HD34 29097656 SRAQVLALYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIEN 5wkp F 3.15 BS01 8Q1 G 1 R6 V9 L10 M16 A39 N43 K44 V46 I52 L55 A59 R3 V6 L7 M13 A36 N40 K41 V43 I49 L52 A56 Q9HD34 29097656 SSRAQVLALYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIEN 5wlg A 2.10 BS01 III C 1 Y7 E9 Y22 S24 Y45 R62 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 L95 Q97 L114 Y123 T143 K146 W147 S150 H155 Y156 Y159 E163 W167 Y171 Y7 E9 Y22 S24 Y45 R62 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 L95 Q97 L114 Y123 T143 K146 W147 S150 H155 Y156 Y159 E163 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEPPP 5wlg E 2.10 BS01 III C 1 N28 D30 Y31 Y50 D95 W96 N28 D30 Y31 Y50 D95 W96 K7N5M4 EAAVTQSPRSKVAVTGGKVTLSCHQTNNHDYMYWYRQDTGHGLRLIHYSYVADSTEKGDIPDGYKASRPSQENFSLILELASLSQTAVYFCASSDWGDTGQLYFGEGSKLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 5wli A 2.20 BS01 III C 1 Y7 E9 Y22 S24 Y45 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 L95 Q97 F116 Y123 T143 K146 W147 H155 Y156 Y159 E163 W167 Y171 Y7 E9 Y22 S24 Y45 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 L95 Q97 F116 Y123 T143 K146 W147 H155 Y156 Y159 E163 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEP 5wlw B 3.32 BS01 8Q1 C 1 V9 L10 I36 A39 F40 N43 K44 V46 L55 V65 I66 V5 L6 I32 A35 F36 N39 K40 V42 L51 V61 I62 Q9HD34 29097656 SRAQVLALYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIEN 5wlw D 3.32 BS01 ZN D 1 D46 C70 H112 D41 C65 H107 Q9H1K1 29097656 MSVDLSTQVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSILAEDAIKAALADYKLKQE 5wlw E 3.32 BS01 PLP E 1 G126 A127 T128 H156 M203 N207 D232 A234 Q235 S255 H257 K258 G73 A74 T75 H103 M150 N154 D179 A181 Q182 S202 H204 K205 2.8.1.7 Q9Y697 29097656 SSLRPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKW 5wlw F 3.32 BS01 8Q1 G 1 R6 L10 M16 I36 F40 N43 K44 V46 L55 A59 D62 I66 R4 L8 M14 I34 F38 N41 K42 V44 L53 A57 D60 I64 Q9HD34 29097656 ASSRAQVLALYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIEN 5wp4 A 1.34 BS01 SAH A 1 R9 W16 M28 G61 G63 R66 F67 L81 D82 F83 I84 A106 D107 V108 N126 W127 L128 R3 W10 M22 G55 G57 R60 F61 L75 D76 F77 I78 A100 D101 V102 N120 W121 L122 2.1.1.103 Q9FR44 29084845 EERDIQKNYWIEHSADLTVEAMMLDSRASDLDKEERPEVLSLLPPYEGKSVLELGAGIGRFTGELAQKAGELIALDFIDNVIKKNESINGHYKNVKFMCADVTSPDLKITDGSLDLIFSNWLLMYLSDKEVELLAERMVGWIKVGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYSKVFQECQTRDAAGNSFELSMIGCKCIGAYVKNKKNQNQICWIWQKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPKTPSAEFSEYIKQRGYDLHDVQAYGQMLKDAGFTDVIAEDRTDQFMQVLKRELDRVEKEKEKFISDFSKEDYDDIVGGWKSKLERCASDEQKWGLFIANKN 5wp4 A 1.34 BS02 PC A 1 Q245 Y246 Y254 V263 S264 D356 Y386 Y400 R404 Y406 K472 Q239 Y240 Y248 V257 S258 D350 Y380 Y394 R398 Y400 K466 2.1.1.103 Q9FR44 29084845 EERDIQKNYWIEHSADLTVEAMMLDSRASDLDKEERPEVLSLLPPYEGKSVLELGAGIGRFTGELAQKAGELIALDFIDNVIKKNESINGHYKNVKFMCADVTSPDLKITDGSLDLIFSNWLLMYLSDKEVELLAERMVGWIKVGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYSKVFQECQTRDAAGNSFELSMIGCKCIGAYVKNKKNQNQICWIWQKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPKTPSAEFSEYIKQRGYDLHDVQAYGQMLKDAGFTDVIAEDRTDQFMQVLKRELDRVEKEKEKFISDFSKEDYDDIVGGWKSKLERCASDEQKWGLFIANKN 5wp4 A 1.34 BS03 SAH A 2 F237 L241 Y246 F262 V263 S264 G290 G292 D312 L313 S314 M317 A337 D338 C339 R355 D356 T357 H360 I361 F231 L235 Y240 F256 V257 S258 G284 G286 D306 L307 S308 M311 A331 D332 C333 R349 D350 T351 H354 I355 2.1.1.103 Q9FR44 29084845 EERDIQKNYWIEHSADLTVEAMMLDSRASDLDKEERPEVLSLLPPYEGKSVLELGAGIGRFTGELAQKAGELIALDFIDNVIKKNESINGHYKNVKFMCADVTSPDLKITDGSLDLIFSNWLLMYLSDKEVELLAERMVGWIKVGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYSKVFQECQTRDAAGNSFELSMIGCKCIGAYVKNKKNQNQICWIWQKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPKTPSAEFSEYIKQRGYDLHDVQAYGQMLKDAGFTDVIAEDRTDQFMQVLKRELDRVEKEKEKFISDFSKEDYDDIVGGWKSKLERCASDEQKWGLFIANKN 5wp4 A 1.34 BS04 PC A 2 W16 M28 M29 L30 W127 M130 Y131 S159 Q163 S164 G165 R169 Y176 W10 M22 M23 L24 W121 M124 Y125 S153 Q157 S158 G159 R163 Y170 2.1.1.103 Q9FR44 29084845 EERDIQKNYWIEHSADLTVEAMMLDSRASDLDKEERPEVLSLLPPYEGKSVLELGAGIGRFTGELAQKAGELIALDFIDNVIKKNESINGHYKNVKFMCADVTSPDLKITDGSLDLIFSNWLLMYLSDKEVELLAERMVGWIKVGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYSKVFQECQTRDAAGNSFELSMIGCKCIGAYVKNKKNQNQICWIWQKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPKTPSAEFSEYIKQRGYDLHDVQAYGQMLKDAGFTDVIAEDRTDQFMQVLKRELDRVEKEKEKFISDFSKEDYDDIVGGWKSKLERCASDEQKWGLFIANKN 5wp5 A 1.50 BS01 SAH A 1 V263 S264 G290 C291 G292 D312 L313 M317 A337 D338 C339 R355 D356 T357 H360 V235 S236 G262 C263 G264 D284 L285 M289 A309 D310 C311 R327 D328 T329 H332 2.1.1.- Q944H0 29084845 EERDIQKSYWMEHRPEVLSLIPPYEGKSVLELGAGIGRFTGELAQKAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVTSPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYTKVFQECQTRDASGNSFELSMVGCKCIGAYVKNKKNQNQICWIWQKVSVENDKDFQRFLDNVQYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGLKCSVEFEVADCTTKTYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAETPSPEFAEYIKQRGYDLHDVQAYGQMLKDAGFDDVIAEDRTDQFVQVLRRELEKVEKEKEEFISDFSEEDYNDIVGGWSAKLERTASGEQKWGLFIADKK 5wp5 A 1.50 BS02 SAH A 2 R9 W16 G61 G63 R66 F67 L81 D82 F83 I84 A106 D107 V108 N126 W127 R3 W10 G33 G35 R38 F39 L53 D54 F55 I56 A78 D79 V80 N98 W99 2.1.1.- Q944H0 29084845 EERDIQKSYWMEHRPEVLSLIPPYEGKSVLELGAGIGRFTGELAQKAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVTSPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYTKVFQECQTRDASGNSFELSMVGCKCIGAYVKNKKNQNQICWIWQKVSVENDKDFQRFLDNVQYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGLKCSVEFEVADCTTKTYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAETPSPEFAEYIKQRGYDLHDVQAYGQMLKDAGFDDVIAEDRTDQFVQVLRRELEKVEKEKEEFISDFSEEDYNDIVGGWSAKLERTASGEQKWGLFIADKK 5ws4 A 3.40 BS01 AT4 A 1 I25 S45 G46 G48 K49 S50 T51 I23 S43 G44 G46 K47 S48 T49 3.6.3.- A0A0D8G707 KQALLEVSNLVREFPAGESTIQILKGIDLTIYEGELVAIVGQSGSGKSTLMNILGCLDRPTSGSYKVNGQETGKLEPDQLAQLRREYFGFIFQRYHLLGDLSAEGNVEVPAVYAGVTPADRKQRATALLTELGLGTKTQNRPSQLSGGQQQRVSIARALMNGGDVILADEPTGALDSHSGVEVMRILRELNAAGHTIILVTHDMQVAKNATRIIEISDGEIISDRPNVPDQSLEEVKSDPDAAPAAWRSTLDRLSEAFQMALLSMNAHRMRTFLTMLGIIIGIASVVTVVALGNGSQQQILSNISSLGTNTITVFQGRGFGDNSKTANFKTLVPADADALMTQPYVSAVSPMVSTSKTMRYQQNEANATINGVSNDYFDVKGLVFKDGQTFDQRSVRDRSQDVVIDTNTQKQFFSDGTNPIGQVVLLGSVPARIIGIVEPQTSGMGSDDTLNVYMPYTTVMSRMLGQAHVRNIVVRINDKYSTSAAENAIVNLLTQRHGAQDIFTMNSDSIRQTIEKTTSTMTLLVSAIAVISLVVGGIGVMNIMLVSVTERTQEIGVRMAVGARQSDILQQFLIEAILVCLIGGVLGVLLSLGLGQLINKFAGGNFAVAYSTTSIVAAFVCSTLIGVVFGFLPAKNAAKLDPVAALSRE 5ws4 B 3.40 BS01 AT4 B 1 F16 I25 S45 G46 G48 K49 S50 T51 F14 I23 S43 G44 G46 K47 S48 T49 3.6.3.- A0A0D8G707 KQALLEVSNLVREFPAGESTIQILKGIDLTIYEGELVAIVGQSGSGKSTLMNILGCLDRPTSGSYKVNGQETGKLEPDQLAQLRREYFGFIFQRYHLLGDLSAEGNVEVPAVYAGVTPADRKQRATALLTELGLGTKTQNRPSQLSGGQQQRVSIARALMNGGDVILADEPTGALDSHSGVEVMRILRELNAAGHTIILVTHDMQVAKNATRIIEISDGEIISDRPNVPDQSLEEVKSDPDAAPAAWRSTLDRLSEAFQMALLSMNAHRMRTFLTMLGIIIGIASVVTVVALGNGSQQQILSNISSLGTNTITVFQGRGFGDNSKTANFKTLVPADADALMTQPYVSAVSPMVSTSKTMRYQQNEANATINGVSNDYFDVKGLVFKDGQTFDQRSVRDRSQDVVIDTNTQKQFFSDGTNPIGQVVLLGSVPARIIGIVEPQTSGMGSDDTLNVYMPYTTVMSRMLGQAHVRNIVVRINDKYSTSAAENAIVNLLTQRHGAQDIFTMNSDSIRQTIEKTTSTMTLLVSAIAVISLVVGGIGVMNIMLVSVTERTQEIGVRMAVGARQSDILQQFLIEAILVCLIGGVLGVLLSLGLGQLINKFAGGNFAVAYSTTSIVAAFVCSTLIGVVFGFLPAKNAAKLDPVAALSRE 5ws8 A 2.62 BS01 MG A 1 K218 E220 D244 K217 E219 D243 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGSTNLIHVHRIGEDDV 5ws8 A 2.62 BS02 OXL A 1 K218 E220 A241 R242 G243 D244 T276 K217 E219 A240 R241 G242 D243 T275 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGSTNLIHVHRIGEDDV 5ws9 A 1.90 BS01 MG A 1 E220 D244 E219 D243 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 A 1.90 BS03 AMP A 1 R351 F373 T374 Q375 S376 T379 A397 V416 P417 K418 M419 M425 G450 P453 G454 T455 V456 G457 S458 T459 R350 F372 T373 Q374 S375 T378 A396 V415 P416 K417 M418 M424 G449 P452 G453 T454 V455 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 A 1.90 BS04 ATP A 1 P13 R33 N35 H38 S310 G311 V315 P12 R32 N34 H37 S309 G310 V314 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 C 1.90 BS03 AMP C 1 R351 F373 T374 Q375 S376 T379 A397 W398 V416 P417 K418 M419 M425 G450 P452 P453 G454 T455 G457 S458 T459 R350 F372 T373 Q374 S375 T378 A396 W397 V415 P416 K417 M418 M424 G449 P451 P452 G453 T454 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 C 1.90 BS04 ATP C 1 P13 R33 N35 H38 D125 K155 S310 G311 V315 P12 R32 N34 H37 D124 K154 S309 G310 V314 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5ws9 D 1.90 BS04 ATP D 1 P13 R33 N35 H38 R74 D125 S310 G311 V315 P12 R32 N34 H37 R73 D124 S309 G310 V314 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa A 2.85 BS01 G6P A 1 L233 E267 N268 H345 P347 R348 T349 G352 R382 R385 L232 E266 N267 H344 P346 R347 T348 G351 R381 R384 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa A 2.85 BS04 PO4 A 1 R351 T374 Q375 S376 G377 D378 T379 V456 G457 R350 T373 Q374 S375 G376 D377 T378 V455 G456 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa B 2.85 BS01 G6P B 1 L233 N268 H345 P347 R348 T349 G352 R382 R385 L232 N267 H344 P346 R347 T348 G351 R381 R384 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa B 2.85 BS04 PO4 B 1 R351 T374 S376 D378 T379 V456 G457 R350 T373 S375 D377 T378 V455 G456 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa C 2.85 BS01 G6P C 1 L233 E267 N268 H345 P347 R348 T349 R382 R385 L232 E266 N267 H344 P346 R347 T348 R381 R384 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa C 2.85 BS03 OXL C 1 K218 E220 D244 T276 K217 E219 D243 T275 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa C 2.85 BS04 PO4 C 1 R351 T374 Q375 S376 T379 V456 G457 R350 T373 Q374 S375 T378 V455 G456 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsa D 2.85 BS04 PO4 D 1 R351 T374 Q375 S376 G377 T379 G457 R350 T373 Q374 S375 G376 T378 G456 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb A 2.25 BS02 G6P A 1 L233 E267 N268 H345 R348 T349 G352 R382 R385 L232 E266 N267 H344 R347 T348 G351 R381 R384 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb B 2.25 BS01 AMP B 1 R351 F373 T374 Q375 S376 G377 D378 T379 W398 V416 P417 M419 M425 G450 P453 G454 T455 V456 G457 S458 T459 R350 F372 T373 Q374 S375 G376 D377 T378 W397 V415 P416 M418 M424 G449 P452 G453 T454 V455 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb C 2.25 BS02 G6P C 1 L233 N268 K270 H345 P347 R348 T349 R382 R385 L232 N267 K269 H344 P346 R347 T348 R381 R384 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb C 2.25 BS04 OXL C 1 K218 E220 A241 G243 D244 T276 K217 E219 A240 G242 D243 T275 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb C 2.25 BS05 PO4 C 1 H38 K72 R74 H37 K71 R73 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb D 2.25 BS02 G6P D 1 E267 N268 H345 P347 R348 T349 G352 R382 R385 E266 N267 H344 P346 R347 T348 G351 R381 R384 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsb D 2.25 BS05 PO4 D 1 N35 S37 H38 N34 S36 H37 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc A 2.40 BS01 AMP A 1 R351 F373 T374 Q375 S376 T379 V416 P417 M419 A449 G450 G454 T455 V456 G457 S458 T459 R350 F372 T373 Q374 S375 T378 V415 P416 M418 A448 G449 G453 T454 V455 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc B 2.40 BS01 AMP B 1 R351 F373 T374 Q375 S376 G377 D378 T379 A397 W398 P417 K418 M419 M425 G450 P453 G454 V456 G457 S458 T459 R350 F372 T373 Q374 S375 G376 D377 T378 A396 W397 P416 K417 M418 M424 G449 P452 G453 V455 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc C 2.40 BS01 AMP C 1 R351 F373 T374 Q375 S376 T379 W398 V416 P417 M419 M425 G450 P453 G454 T455 G457 S458 T459 R350 F372 T373 Q374 S375 T378 W397 V415 P416 M418 M424 G449 P452 G453 T454 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc D 2.40 BS01 AMP D 1 R351 F373 T374 Q375 S376 T379 A397 V416 P417 K418 M419 G450 G454 T455 V456 G457 S458 T459 R350 F372 T373 Q374 S375 T378 A396 V415 P416 K417 M418 G449 G453 T454 V455 G456 S457 T458 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wsc D 2.40 BS05 PO4 D 1 N35 H38 K72 R74 N34 H37 K71 R73 2.7.1.40 P9WKE5 TRRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAVGVLADLQGPKIRLGRFASGATHWAEGETVRITVGACEGSHDRVSTTYKRLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALSEKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV 5wvo A 2.00 BS01 III D 1 D32 K33 E34 G35 I36 Q40 L71 L73 R74 C76 D32 K33 E34 G35 I36 Q40 L71 L73 R74 C76 P62979 29053958 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGC 5wvo C 2.00 BS01 III D 1 I427 E428 N430 E432 I461 N462 E463 W464 W465 I466 T467 F469 E485 Q517 Q560 S563 Y564 A567 G568 D569 D571 E572 I68 E69 N71 E73 I102 N103 E104 W105 W106 I107 T108 F110 E126 Q158 Q201 S204 Y205 A208 G209 D210 D212 E213 2.1.1.37 P26358 29053958 CIQCGLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVT 5wvo C 2.00 BS02 ZN C 1 C353 C356 C414 H418 C1 C4 C55 H59 2.1.1.37 P26358 29053958 CIQCGLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVT 5wwd A 1.39 BS01 2ME A 1 N75 N76 V77 W128 K132 N70 N71 V72 W123 K127 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 29066356 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTHG 5wwd A 1.39 BS02 MG A 1 G41 H42 G36 H37 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 29066356 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTHG 5wwd A 1.39 BS03 MG A 2 E56 E59 E60 E107 E51 E54 E55 E102 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 29066356 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTHG 5wwd B 1.39 BS02 MG B 2 E56 E59 E60 E107 K110 E51 E54 E55 E102 K105 3.6.1.55,3.6.1.67,3.6.1.22 Q9CA40 29066356 AIPRVAVVVFILNGNSILLGRRRSSIGNSTFALPGGHLEFGESFEECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVSIRAVLVDPSQEPKNMEPEKCEGWDWYDWENLPKPLFWPLEKLFGSGFNPFTH 5y1e A 1.90 BS01 NAD A 1 G6 G9 Q10 I11 D32 L33 C46 D47 I48 L69 A70 A71 L73 V87 P109 S110 Y136 K140 Y163 P164 L166 G6 G9 Q10 I11 D32 L33 C46 D47 I48 L69 A70 A71 L73 V87 P109 S110 Y136 K140 Y163 P164 L166 D6PBM7 28992410 MILVTGALGQIGTELVLALQEKYGNDKIIASDLKEPENYHCKFEKCDIRDIETYERINNENKIEIVYHLAAILSAAGEKNPELCHDVNYNGLENVLKTAKKYNQKLFCPSSIAVFGPDVPKEMTPQNVELNPKTVYGITKVKGEELCDTYFKEHGIDVRGIRYPGLISWKHKPSGGTTDYAVEMYFDAVESGKYECFVNRNTRLPMMFMDDAIRATLELMDAPLDSLNYHSNYNLSSMSFSAEELEKEISAHVDFNCLYKPDYRQDIADTWPISINDDDARKDWGWEPKFDISKMTEEMITNLRRLNE 5y1e A 1.90 BS02 SER A 1 S74 S111 Y136 G176 T177 T178 S74 S111 Y136 G176 T177 T178 D6PBM7 28992410 MILVTGALGQIGTELVLALQEKYGNDKIIASDLKEPENYHCKFEKCDIRDIETYERINNENKIEIVYHLAAILSAAGEKNPELCHDVNYNGLENVLKTAKKYNQKLFCPSSIAVFGPDVPKEMTPQNVELNPKTVYGITKVKGEELCDTYFKEHGIDVRGIRYPGLISWKHKPSGGTTDYAVEMYFDAVESGKYECFVNRNTRLPMMFMDDAIRATLELMDAPLDSLNYHSNYNLSSMSFSAEELEKEISAHVDFNCLYKPDYRQDIADTWPISINDDDARKDWGWEPKFDISKMTEEMITNLRRLNE 5y1g A 1.35 BS01 AKB A 1 S74 S111 G176 T177 T178 W271 S76 S113 G178 T179 T180 W273 D6PBM7 28992410 SHMILVTGALGQIGTELVLALQEKYGNDKIIASDLKEPENYHCKFEKCDIRDIETYERINNENKIEIVYHLAAILSAAGEKNPELCHDVNYNGLENVLKTAKKYNQKLFCPSSIAVFGPDVPKEMTPQNVELNPKTVYGITKVKGEELCDTYFKEHGIDVRGIRYPGLISWKHKPSGGTTDYAVEMYFDAVESGKYECFVNRNTRLPMMFMDDAIRATLELMDAPLDSLNYHSNYNLSSMSFSAEELEKEISAHVDFNCLYKPDYRQDIADTWPISINDDDARKDWGWEPKFDISKMTEEMITNLRRLNE 5y1y A 1.91 BS01 HNQ A 1 P82 V87 L92 L94 C136 N140 I146 P40 V45 L50 L52 C94 N98 I104 O60885 29087414 MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPT 5y7w A 2.25 BS01 III C 1 Q266 G270 I272 I273 S274 I275 V292 R293 Y297 F300 R311 Q26 G30 I32 I33 S34 I35 V52 R53 Y57 F60 R71 2.3.1.48 P70365 29090910 DIFEAQKIEWHEGAHMTGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIID 5y7w B 2.25 BS01 III D 1 T269 I273 I275 E289 V292 R293 Y297 F300 R311 F314 T10 I14 I16 E30 V33 R34 Y38 F41 R52 F55 2.3.1.48 P70365 29090910 ESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDRE 5yco C 2.20 BS01 III F 1 M40 S43 H44 V45 S46 L47 G127 I128 P129 A208 D232 P234 A252 P253 I255 M40 S43 H44 V45 S46 L47 G127 I128 P129 A201 D225 P227 A245 P246 I248 P12004 28951215 MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI 5yl4 B 2.64 BS02 8WR B 1 Q134 L135 T136 N165 F167 E198 Y200 M233 V236 T237 C239 L240 L246 L250 L253 M257 A314 A315 I316 T351 A352 I368 Q134 L135 T136 N165 F167 E198 Y200 M233 V236 T237 C239 L240 L246 L250 L253 M257 A310 A311 I312 T347 A348 I364 A0A0R4I995 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5yl4 D 2.64 BS01 GTP D 1 G10 Q11 C12 A97 G98 N99 S138 G140 G141 G142 T143 G144 V175 S176 E181 N204 Y222 N226 G10 Q11 C12 A97 G98 N99 S138 G140 G141 G142 T143 G144 V175 S176 E181 N204 Y222 N226 A0A0R4I995 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 6aud A 2.02 BS01 BWY A 1 W812 I831 K833 I879 E880 I881 V882 A885 K890 M953 F961 I963 D964 W573 I592 K594 I640 E641 I642 V643 A646 K651 M714 F722 I724 D725 2.7.1.153,2.7.11.1 P48736 28947940 MSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEECDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKLTSATNPDKENSMSISILLDNHPIAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCTVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHIERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLV 6ayw A 2.05 BS01 C2V A 1 L20 V28 A41 V74 F90 D91 L92 V93 E140 N141 L143 D157 L13 V21 A34 V67 F83 D84 L85 V86 E133 N134 L136 D150 2.7.11.17 Q13557 TRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 6az0 A 3.40 BS01 III G 1 V353 Y354 V355 V75 Y76 V77 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 A 3.40 BS02 ATP A 1 D282 C284 G285 C286 P323 G324 T325 G326 K327 T328 L329 I456 H460 G484 A485 D4 C6 G7 C8 P45 G46 T47 G48 K49 T50 L51 I178 H182 G206 A207 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 A 3.40 BS03 ZN A 1 H540 H544 D618 H262 H266 D340 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 B 3.40 BS02 ATP A 1 R435 R438 R157 R160 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 B 3.40 BS03 ATP B 1 D282 V283 C284 G285 C286 P323 G324 T325 G326 K327 T328 L329 H460 G484 A485 D4 V5 C6 G7 C8 P45 G46 T47 G48 K49 T50 L51 H182 G206 A207 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 B 3.40 BS05 MG B 1 T328 D380 T50 D102 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 C 3.40 BS02 ATP C 1 D282 V283 C284 G285 C286 P323 G324 T325 G326 K327 T328 L329 N424 H460 D4 V5 C6 G7 C8 P45 G46 T47 G48 K49 T50 L51 N146 H182 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 D 3.40 BS01 III G 1 Y354 Y396 Y76 Y118 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6az0 D 3.40 BS02 ATP C 1 D409 R438 D131 R160 B3LL85 29097521 KFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDQLDAIGGKRNPKDQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSEEWESWSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLAKLKT 6b39 A 2.39 BS01 SAH A 1 V242 A244 M279 G280 G282 D315 Y316 G338 D339 I340 S365 F366 L367 H369 D370 P372 V237 A239 M274 G275 G277 D310 Y311 G333 D334 I335 S360 F361 L362 H364 D365 P367 A0A1U7N2Z8 29096064 ENLYFQSNALDKINRYAHGFVAVPVICACSEAGVFELLSQKKSLKLEEIVEHLAANSGHLMVAMRLLESLSFLYRSQAEEYILTEQSQQHQIIPKALMSLYKYPFELYLKGEVETGISNWINCSSRRWDTENSLLSDLLDGVLLIPLLLELKKQNLLDESKKIFNTLTNSLKQELSTLFINLGWAEEKTEGLYLTDIGRFMRDRSLNLGTTASYAPMLLQMKELLFGNPQRVFQRNVVASGFQHEKFFADTDKIIISIFNQQPIEEQPIYIVDMGCGDGTLLKRIYKIIKQFSARGKVLTEYPIIMVGVDYNQEALDVTDKNLVDIPHLVIPGDIGAPEKLLEQLKAQGIEPEKVLHIRSFLDHDRPFIAPKNTEIAQARSQLDYQVVDVDREGKLIPPHIAVQSLVEHLERWSSIITRHGLLLLEVHSLTPAVVKKYIDESESLHFDAYHAFSMQHLVEADVFLMAAAEVGLFSRKEAFRKYPKTLPLTRITVNHFEKRKYQIRYATVNDIPNLLKCATFNPPVNEPFFQVLLKQTPTAHLLLEYQGELVAAIFTETKNSNEVLGIREFLVRTSVENWQVLAKDLLEFVEQWGVVKPGIKEIEGLLKYHEAISNFQKSKWYQS 6b3a A 1.78 BS01 SAM A 1 M279 G280 G282 D315 Y316 N317 G338 D339 I340 S365 F366 L367 M281 G282 G284 D317 Y318 N319 G340 D341 I342 S367 F368 L369 A0A1U7N2Z8 29096064 NLYFQSNALDKINRYAHGFVAVPVICACSEAGVFELLSQKKSLKLEEIVEHLAANSGHLMVAMRLLESLSFLYRSQAEEYILTEQSQQHQIIPKALMSLYKYPFELYLKGEVETGISNWINCSSRRWDTENSLLSDLLDGVLLIPLLLELKKQNLLDESKKIFNTLTNSLKQELSTLFINLGWAELYLTDIGRFMRDRSLNLGTTASYAPMLLQMKELLFGNPQRVFQRNKTEKERHVNRTLNVVASGFQHEKFFADTDKIIISIFNQQPIEEQPIYIVDMGCGDGTLLKRIYKIIKQFSARGKVLTEYPIIMVGVDYNQEALDVTDKNLVDIPHLVIPGDIGAPEKLLEQLKAQGIEPEKVLHIRSFLDHDRPFIAPKNTEIAQARSQLDYQVVDVDREGKLIPPHIAVQSLVEHLERWSSIITRHGLLLLEVHSLTPAVVKKYIDESESLHFDAYHAFSMQHLVEADVFLMAAAEVGLFSRKEAFRKYPKTLPLTRITVNHFEKRKYQIRYATVNDIPNLLKCATFNPPVNEPFFQVLLKQTPTAHLLLEYQGELVAAIFTETKNSNEVLGIREFLVRTSVENWQVLAKDLLEFVEQWGVVKPGIKEIEGLLKYHEAISNFQKSKWYQS 6b3a A 1.78 BS02 MN A 1 H369 H456 Q461 H371 H458 Q463 A0A1U7N2Z8 29096064 NLYFQSNALDKINRYAHGFVAVPVICACSEAGVFELLSQKKSLKLEEIVEHLAANSGHLMVAMRLLESLSFLYRSQAEEYILTEQSQQHQIIPKALMSLYKYPFELYLKGEVETGISNWINCSSRRWDTENSLLSDLLDGVLLIPLLLELKKQNLLDESKKIFNTLTNSLKQELSTLFINLGWAELYLTDIGRFMRDRSLNLGTTASYAPMLLQMKELLFGNPQRVFQRNKTEKERHVNRTLNVVASGFQHEKFFADTDKIIISIFNQQPIEEQPIYIVDMGCGDGTLLKRIYKIIKQFSARGKVLTEYPIIMVGVDYNQEALDVTDKNLVDIPHLVIPGDIGAPEKLLEQLKAQGIEPEKVLHIRSFLDHDRPFIAPKNTEIAQARSQLDYQVVDVDREGKLIPPHIAVQSLVEHLERWSSIITRHGLLLLEVHSLTPAVVKKYIDESESLHFDAYHAFSMQHLVEADVFLMAAAEVGLFSRKEAFRKYPKTLPLTRITVNHFEKRKYQIRYATVNDIPNLLKCATFNPPVNEPFFQVLLKQTPTAHLLLEYQGELVAAIFTETKNSNEVLGIREFLVRTSVENWQVLAKDLLEFVEQWGVVKPGIKEIEGLLKYHEAISNFQKSKWYQS 6b3b A 1.85 BS01 SAM A 1 H249 F253 M279 G280 G282 D315 Y316 N317 A320 G338 D339 I340 S365 F366 L367 P372 H244 F248 M274 G275 G277 D310 Y311 N312 A315 G333 D334 I335 S360 F361 L362 P367 A0A1U7N2Z8 29096064 ALDKINRYAHGFVAVPVICACSEAGVFELLSQKKSLKLEEIVEHLAANSGHLMVAMRLLESLSFLYRSQAEEYILTEQSQQHQIIPKALMSLYKYPFELYLKGEVETGISNWINCSSRRWDTENSLLSDLLDGVLLIPLLLELKKQNLLIFNTLTNSLKQELSTLFINLGWAEEKTEGLYLTDIGRFMRDRSLNLGTTASYAPMLLQMKELLFGNPQRVFQRNKTEKERHVNRTLNVVASGFQHEKFFADTDKIIISIFNQQPIEEQPIYIVDMGCGDGTLLKRIYKIIKQFSARGKVLTEYPIIMVGVDYNQEALDVTDKNLVDIPHLVIPGDIGAPEKLLEQLKAQGIEPEKVLHIRSFLDHDRPFIAPKNTEIAQARSQLDYQVVDVDREGKLIPPHIAVQSLVEHLERWSSIITRHGLLLLEVHSLTPAVVKKYIDESESLHFDAYHAFSMQHLVEADVFLMAAAEVGLFSRKEAFRKYPKTLPLTRITVNHFEKRKYQIRYATVNDIPNLLKCATFNPPVNEPFFQVLLKQTPTAHLLLEYQGELVAAIFTETKNSNEVLGIREFLVRTSVENWQVLAKDLLEFVEQWGVVKPGIKEIEGLLKYHEAISNFQKSKWYQS 6b3b A 1.85 BS03 MLI A 1 Y206 N241 S245 H249 H369 H456 Q461 Y201 N236 S240 H244 H364 H451 Q456 A0A1U7N2Z8 29096064 ALDKINRYAHGFVAVPVICACSEAGVFELLSQKKSLKLEEIVEHLAANSGHLMVAMRLLESLSFLYRSQAEEYILTEQSQQHQIIPKALMSLYKYPFELYLKGEVETGISNWINCSSRRWDTENSLLSDLLDGVLLIPLLLELKKQNLLIFNTLTNSLKQELSTLFINLGWAEEKTEGLYLTDIGRFMRDRSLNLGTTASYAPMLLQMKELLFGNPQRVFQRNKTEKERHVNRTLNVVASGFQHEKFFADTDKIIISIFNQQPIEEQPIYIVDMGCGDGTLLKRIYKIIKQFSARGKVLTEYPIIMVGVDYNQEALDVTDKNLVDIPHLVIPGDIGAPEKLLEQLKAQGIEPEKVLHIRSFLDHDRPFIAPKNTEIAQARSQLDYQVVDVDREGKLIPPHIAVQSLVEHLERWSSIITRHGLLLLEVHSLTPAVVKKYIDESESLHFDAYHAFSMQHLVEADVFLMAAAEVGLFSRKEAFRKYPKTLPLTRITVNHFEKRKYQIRYATVNDIPNLLKCATFNPPVNEPFFQVLLKQTPTAHLLLEYQGELVAAIFTETKNSNEVLGIREFLVRTSVENWQVLAKDLLEFVEQWGVVKPGIKEIEGLLKYHEAISNFQKSKWYQS 6b6h C 3.90 BS01 NUC 1 1 R175 W183 D185 D199 R200 R371 E374 R394 R473 R542 R173 W181 D183 D197 R198 R369 E372 R392 R471 R540 2.7.7.6 B7MIX3 YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 6b6h C 3.90 BS02 NUC 2 1 R202 R478 N494 K496 S508 F514 E541 G1261 K1262 Q1268 R1269 G1271 R200 R476 N492 K494 S506 F512 E539 G1259 K1260 Q1266 R1267 G1269 2.7.7.6 B7MIX3 YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 6b6h D 3.90 BS01 NUC 1 1 Y46 P121 K1311 Y32 P107 K1272 2.7.7.6 P0A8T8 EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6b6h D 3.90 BS02 NUC 2 1 R259 S319 N320 K334 R339 R346 R352 T790 A791 G794 Y795 M1189 Q1326 E1327 R245 S305 N306 K320 R325 R332 R338 T776 A777 G780 Y781 M1150 Q1287 E1288 2.7.7.6 P0A8T8 EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6b6h D 3.90 BS03 NUC 3 1 R425 A426 D462 D464 R411 A412 D448 D450 2.7.7.6 P0A8T8 EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6b6h D 3.90 BS04 ZN D 1 C70 L71 C72 C85 C88 C56 L57 C58 C71 C74 2.7.7.6 P0A8T8 EEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 6b6h F 3.90 BS01 NUC 1 1 V98 R99 M102 M105 G106 L110 N383 R385 L386 S389 K392 R397 K418 F419 E420 R423 Y425 K426 S428 T429 Y430 T432 W433 W434 Q437 R441 R451 P453 H455 M456 R554 F580 D581 T583 R586 K593 V20 R21 M24 M27 G28 L32 N267 R269 L270 S273 K276 R281 K302 F303 E304 R307 Y309 K310 S312 T313 Y314 T316 W317 W318 Q321 R325 R335 P337 H339 M340 R438 F464 D465 T467 R470 K477 P00579 AAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDPNAENSIDPELAREKFAELRAQYVVTRDTIKAKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD 6b6h F 3.90 BS02 NUC 2 1 R397 G398 Q437 T440 I443 N461 R465 E503 P510 I511 G512 D513 D516 T572 L573 E574 E585 R588 R281 G282 Q321 T324 I327 N345 R349 E387 P394 I395 G396 D397 D400 T456 L457 E458 E469 R472 P00579 AAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDPNAENSIDPELAREKFAELRAQYVVTRDTIKAKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD 6b6h G 3.90 BS02 NUC 2 1 D138 V139 R185 H199 G200 K201 D130 V131 R177 H191 G192 K193 P0ACK0 PTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 6b6h G 3.90 BS03 CMP G 1 I30 V49 L61 I70 G71 E72 L73 R82 S83 A84 V86 R123 T127 I22 V41 L53 I62 G63 E64 L65 R74 S75 A76 V78 R115 T119 P0ACK0 PTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 6b6h H 3.90 BS01 NUC 1 1 V139 C178 S179 T182 H199 K201 V131 C170 S171 T174 H191 K193 P0ACK0 PTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 6b6h H 3.90 BS04 CMP H 1 I30 L61 I70 G71 E72 L73 G74 R82 S83 A84 R123 T127 I22 L53 I62 G63 E64 L65 G66 R74 S75 A76 R115 T119 P0ACK0 PTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 6b6h I 3.90 BS02 NUC 2 1 R265 T292 P293 N294 L295 G296 K298 S299 R16 T43 P44 N45 L46 G47 K49 S50 2.7.7.6 P0A7Z6 DPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPA 6bfd A 1.62 BS01 DJS A 1 S10 Q12 G13 L30 D32 G34 S35 Y71 T72 Q73 F108 I110 W115 I118 D228 G230 T231 T232 N233 R235 S18 Q20 G21 L38 D40 G42 S43 Y79 T80 Q81 F116 I118 W123 I126 D236 G238 T239 T240 N241 R243 3.4.23.46 P56817 29088532 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 6bfe A 1.51 BS01 DJV A 1 L30 D32 G34 S35 V69 P70 Y71 T72 Q73 G74 F108 I110 W115 I118 I126 R128 Y198 I226 D228 G230 T231 L38 D40 G42 S43 V77 P78 Y79 T80 Q81 G82 F116 I118 W123 I126 I134 R136 Y206 I234 D236 G238 T239 3.4.23.46 P56817 29088532 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 6bfw A 1.84 BS01 DK7 A 1 L30 D32 G34 S35 V69 Y71 T72 G74 F108 I110 W115 I118 Y198 I226 D228 G230 T231 L38 D40 G42 S43 V77 Y79 T80 G82 F116 I118 W123 I126 Y206 I234 D236 G238 T239 3.4.23.46 P56817 29088532 PGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 6bfx A 1.99 BS01 DKJ A 1 L30 D32 G34 S35 V69 P70 Y71 T72 F108 I110 W115 I118 I126 Y198 I226 D228 G230 T231 L34 D36 G38 S39 V73 P74 Y75 T76 F112 I114 W119 I122 I130 Y202 I230 D232 G234 T235 3.4.23.46 P56817 29088532 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 6el8 A 1.61 BS01 NUC B 1 N316 R319 H320 S323 K330 G341 C342 W344 N49 R52 H53 S56 K63 G70 C71 W73 O15353 MPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSKGCLWALNPAKIDKMQEELQK 6el8 A 1.61 BS02 NUC C 1 K270 S274 Y275 N316 S317 K3 S7 Y8 N49 S50 O15353 MPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSKGCLWALNPAKIDKMQEELQK 6el8 D 1.61 BS02 NUC F 1 K270 S274 Y275 N316 S317 H320 K340 K4 S8 Y9 N50 S51 H54 K67 O15353 SMPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVEKGCLWALNPAKIDKMQEELQKWK 6eoj B 3.55 BS01 ZN B 1 C67 C75 C81 H85 C67 C75 C81 H85 Q06102 29074584 PSLIHPDTAKYPFKFEPFLRQEYSFSLDPDRPICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPE 6erp C 4.50 BS01 NUC D 1 S56 Y57 L58 T78 I81 R82 A85 Q100 Y103 W107 K146 K147 K156 R157 R159 N163 A167 P178 Q179 S14 Y15 L16 T36 I39 R40 A43 Q58 Y61 W65 K104 K105 K114 R115 R117 N121 A125 P136 Q137 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erp C 4.50 BS02 NUC E 1 K51 K52 V54 L58 T77 K147 R157 P158 S160 Y162 N163 Q179 L182 K186 E208 Y211 R232 R233 K9 K10 V12 L16 T35 K105 R115 P116 S118 Y120 N121 Q137 L140 K144 E166 Y169 R190 R191 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erp G 4.50 BS01 NUC H 1 S55 Y57 L58 T78 I81 R82 A85 Y103 W107 K139 K147 K156 R157 R159 N163 A167 F170 P178 Q179 L182 S13 Y15 L16 T36 I39 R40 A43 Y61 W65 K97 K105 K114 R115 R117 N121 A125 F128 P136 Q137 L140 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erp G 4.50 BS02 NUC I 1 K51 K52 V54 L58 K62 L65 K69 T77 I81 R140 K146 T150 R157 Y162 Q179 L182 K186 E208 Y211 R232 R233 K9 K10 V12 L16 K20 L23 K27 T35 I39 R98 K104 T108 R115 Y120 Q137 L140 K144 E166 Y169 R190 R191 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erp A 4.50 BS01 NUC D 1 I125 V615 T1112 K1116 I4 V420 T893 K897 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEAPELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erp A 4.50 BS02 NUC E 1 R502 Q616 Q617 I618 G619 S1097 I1098 T1099 Y1100 T1101 R1113 R310 Q421 Q422 I423 G424 S878 I879 T880 Y881 T882 R894 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEAPELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erp B 4.50 BS01 NUC H 1 V615 R1059 V420 R835 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erp B 4.50 BS02 NUC I 1 R139 Q254 R502 Y610 Q616 Q617 I618 G619 T1099 Y1100 T1101 H1102 R1113 R18 Q62 R310 Y415 Q421 Q422 I423 G424 T872 Y873 T874 H875 R886 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erp F 4.50 BS01 NUC D 1 K201 R202 W205 K236 K124 R125 W128 K159 2.1.1.- Q9H5Q4 KRYVTDRRLAETLAQIYLGHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDET 6erp J 4.50 BS01 NUC H 1 K201 R202 W205 H248 K325 K124 R125 W128 H171 K221 2.1.1.- Q9H5Q4 KRYVTDRRLAETLAQIYLGHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDET 6erp J 4.50 BS02 NUC I 1 R330 S332 R226 S228 2.1.1.- Q9H5Q4 KRYVTDRRLAETLAQIYLGHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDET 6erq C 4.50 BS01 NUC D 1 S56 Y57 T78 I81 R82 A85 W88 R89 Q100 Y103 W107 K147 K156 R157 R159 Y162 N163 A167 F170 P178 L182 S14 Y15 T36 I39 R40 A43 W46 R47 Q58 Y61 W65 K105 K114 R115 R117 Y120 N121 A125 F128 P136 L140 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erq C 4.50 BS02 NUC E 1 K51 K52 S55 Y57 L58 T77 R140 R157 S160 Y162 Q179 L182 K186 E208 Y211 R232 R233 K9 K10 S13 Y15 L16 T35 R98 R115 S118 Y120 Q137 L140 K144 E166 Y169 R190 R191 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erq G 4.50 BS01 NUC H 1 S55 S56 Y57 L58 T78 I81 R82 A85 Q100 Y103 W107 K139 K156 R157 R159 Y162 N163 A167 F170 P178 S13 S14 Y15 L16 T36 I39 R40 A43 Q58 Y61 W65 K97 K114 R115 R117 Y120 N121 A125 F128 P136 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erq G 4.50 BS02 NUC I 1 K51 K52 V54 S55 L58 S61 K62 L65 K69 T77 R140 K146 K147 T150 R157 P158 S160 Y162 N163 P178 Q179 L182 K186 E208 Y211 R232 R233 K9 K10 V12 S13 L16 S19 K20 L23 K27 T35 R98 K104 K105 T108 R115 P116 S118 Y120 N121 P136 Q137 L140 K144 E166 Y169 R190 R191 Q00059 SSVLASSPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRT 6erq A 4.50 BS01 NUC D 1 I125 Q222 V615 Q616 R1059 T1112 K1116 I4 Q30 V420 Q421 R843 T893 K897 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEAPELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erq B 4.50 BS01 NUC H 1 Q222 V615 Q616 R1059 Q30 V420 Q421 R834 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erq B 4.50 BS02 NUC I 1 R139 Q254 R502 Q616 Q617 I618 D1085 T1099 Y1100 T1101 H1102 N1103 R1113 R18 Q62 R310 Q421 Q422 I423 D860 T871 Y872 T873 H874 N875 R885 2.7.7.6 O00411 WAKILEKDKRTQQMRMQRLKAKLQMQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS 6erq F 4.50 BS01 NUC D 1 K201 R202 W205 K124 R125 W128 2.1.1.- Q9H5Q4 KRYVTDRRLAETLAQIYLGHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDET 6erq F 4.50 BS02 NUC E 1 G329 R330 G225 R226 2.1.1.- Q9H5Q4 KRYVTDRRLAETLAQIYLGHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDET 6erq J 4.50 BS02 NUC I 1 G329 R330 S332 G225 R226 S228 2.1.1.- Q9H5Q4 KRYVTDRRLAETLAQIYLGHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDET 6eww A 2.68 BS01 III E 1 V46 K49 N50 R56 K120 R127 Y128 G169 L172 N173 I217 D223 N224 W228 V47 K50 N51 R57 K117 R124 Y125 G166 L169 N170 I205 D211 N212 W216 P63104 HMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAEKDSTLIMQLLRDNLTLWT 6eww C 2.68 BS01 III G 1 K49 R56 R127 Y128 L172 N173 V176 E180 L220 N224 L227 K49 R56 R122 Y123 L163 N164 V167 E171 L211 N215 L218 P63104 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 6eww B 2.68 BS01 III F 1 S45 V46 K49 N50 R56 R60 K120 R127 Y128 L172 N173 V176 E180 I217 N224 S45 V46 K49 N50 R56 R60 K116 R123 Y124 L168 N169 V172 E176 I210 N217 P63104 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDEESYKDSTLIMQLLRDNLTLWT 6eww D 2.68 BS01 III H 1 K49 R56 R127 Y128 L172 N173 V176 I217 N224 W228 K48 R55 R117 Y118 L162 N163 V166 I207 N214 W218 P63104 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWT