5b69 A 2.50 BS01 1GP A 1 L21 F78 Y171 E173 S176 G177 G201 G202 G203 G224 T225 L21 F78 Y171 E173 S176 G177 G201 G202 G203 G224 T225 2.5.1.41 Q9HJH3 MMTVLEDMLRKTRNGKVHMTLIDPGAKPPQECARIAEEAEMAGTDFIMVGGSTDIDSRAMDEAISAIKAKTDLKVIIFPGSSLMISPKADAIFFMSLLNSGSLEYVVGHQVKAAIPLSAMKIEKIPMAYLVFDPGMTVGRVGKAHLIPRDDEKTALSYALAAQYFGFRLVYFEAGSGSPYHVGENVVRRVKQELDIPVIVGGGIRTPEAAKALAQAGADMIVTGTIAERSVNVYEALHPIVESIKE 5gix A 2.80 BS01 6WF A 1 Y150 Q196 K199 C200 L238 H242 C245 C253 R257 L260 I290 A291 Y148 Q194 K197 C198 L236 H240 C243 C251 R255 L258 I288 A289 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix A 2.80 BS03 PLM A 2 R10 L14 L22 L66 L69 F70 Y150 P152 L250 L251 A254 R257 L283 L284 S287 R8 L12 L20 L64 L67 F68 Y148 P150 L248 L249 A252 R255 L281 L282 S285 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix A 2.80 BS04 PLM A 3 S342 V344 R348 L387 M446 E450 L453 R485 S340 V342 R346 L385 M444 E448 L451 R483 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix A 2.80 BS05 PLM A 4 R410 Y411 V418 L457 L460 H464 R485 F488 S489 R408 Y409 V416 L455 L458 H462 R483 F486 S487 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix A 2.80 BS06 PLM A 5 Y401 F502 F507 K525 A528 L532 V547 M548 F551 S579 Y399 F500 F505 K523 A526 L530 V545 M546 F549 S577 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix A 2.80 BS07 PLM A 6 R209 A210 A213 V216 D324 K351 R207 A208 A211 V214 D322 K349 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix B 2.80 BS01 6WF B 1 Y150 Q196 K199 C200 V241 H242 C245 C253 R257 I290 A291 Y148 Q194 K197 C198 V239 H240 C243 C251 R255 I288 A289 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix B 2.80 BS02 PLM B 1 R117 L135 Y138 A158 Y161 F165 R115 L133 Y136 A156 Y159 F163 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix B 2.80 BS03 PLM B 2 R10 L14 L22 V46 L66 L69 F70 Y150 L251 A254 R257 A258 L284 S287 R8 L12 L20 V44 L64 L67 F68 Y148 L249 A252 R255 A256 L282 S285 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix B 2.80 BS04 PLM B 3 S342 V344 R348 L387 E450 L453 R485 S340 V342 R346 L385 E448 L451 R483 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix B 2.80 BS05 PLM B 4 Y411 V418 L457 L460 H464 V473 F488 S489 Y409 V416 L455 L458 H462 V471 F486 S487 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gix B 2.80 BS06 PLM B 5 Y401 F502 F507 K525 A528 L532 V547 F551 A552 S579 Q580 Y399 F500 F505 K523 A526 L530 V545 F549 A550 S577 Q578 P02768 27441502 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS02 PLM A 2 R10 L14 L22 V23 V46 L66 L69 Y150 A254 R257 L283 L284 S287 R8 L12 L20 V21 V44 L64 L67 Y148 A252 R255 L281 L282 S285 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS03 PLM A 3 S342 V344 R348 P384 L387 V433 G434 L453 R485 S340 V342 R346 P382 L385 V431 G432 L451 R483 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS04 PLM A 4 L387 Y411 V418 L460 H464 R485 F488 S489 L385 Y409 V416 L458 H462 R483 F486 S487 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS05 PLM A 5 Y401 F502 F507 K525 A528 L529 L532 V547 F551 S579 Q580 Y399 F500 F505 K523 A526 L527 L530 V545 F549 S577 Q578 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS06 PLM A 6 R209 V216 D324 L327 G328 K351 E354 R207 V214 D322 L325 G326 K349 E352 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS07 7GE A 1 H146 Y161 G189 K190 S193 H144 Y159 G187 K188 S191 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5giy A 2.54 BS08 7GE A 2 K199 R218 L238 H242 R257 S287 A291 K197 R216 L236 H240 R255 S285 A289 P02768 HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAAL 5gt1 A 1.85 BS01 ZN A 1 H395 D399 H475 H36 D40 H116 A0A0F7PV22 28281568 KDTWGWPFPSVGEGYFSGAQLFGVNPGGEFRMNGFHDGLDFGSIDHPGSAVHAVHSGVVTQIGYIAGLENYVVVRSDEYTFVYQEAFSNKGNISVKVGQQINTGDVIGYRDTSHLHLGITRETNVMKAIANSFNNNGTWLDPRALIKNGIANQ 5gub A 1.78 BS01 CA A 1 D189 N191 N193 K195 D197 E198 D163 N165 N167 K169 D171 E172 D1AWE0 28432302 PKETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMDNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF 5gub A 1.78 BS02 GCD A 1 Y146 W284 A286 S287 L389 Q405 Y409 E410 Y120 W258 A260 S261 L363 Q379 Y383 E384 D1AWE0 28432302 PKETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMDNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF 5gx7 A 1.99 BS02 NG6 A 1 H36 L37 Y146 Q155 R204 A205 K210 L266 W284 L326 R393 H10 L11 Y120 Q129 R178 A179 K184 L240 W258 L300 R367 D1AWE0 28432302 PKETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMDNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF 5gx7 C 1.99 BS02 NG6 C 1 H36 L37 Y146 Q155 R204 W284 L326 R393 Q398 H10 L11 Y120 Q129 R178 W258 L300 R367 Q372 D1AWE0 28432302 PKETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMDNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF 5gx8 A 1.78 BS02 SO4 A 1 N207 R209 R456 N180 R182 R429 D1AWE0 28432302 KETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMDNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF 5gx8 A 1.78 BS03 SO4 B 1 K442 K446 K415 K419 D1AWE0 28432302 KETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNLMLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENPRYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVDELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWYEENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNNLGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYLGGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFTDKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYMDNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKEWDAYIKRLENLGLSKAEQIQNEAF 5irb A 2.00 BS01 CA A 1 T197 D199 V201 E206 T16 D18 V20 E25 A1YIY2 LNQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 5irb A 2.00 BS02 CA A 2 D390 S392 A393 D477 D209 S211 A212 D296 A1YIY2 LNQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 5irb A 2.00 BS03 CA A 3 D407 T490 D226 T309 A1YIY2 LNQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 5irb A 2.00 BS06 CA A 6 D258 D260 I262 D77 D79 I81 A1YIY2 LNQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 5irb A 2.00 BS07 CA A 7 D362 S364 D181 S183 A1YIY2 LNQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 5irb A 2.00 BS09 CA A 9 D466 A468 D285 A287 A1YIY2 LNQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVD 5irb B 2.00 BS04 CA B 3 D390 S392 D477 D208 S210 D295 A1YIY2 NQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDLE 5irb B 2.00 BS10 MG B 2 I193 E283 I11 E101 A1YIY2 NQSPLLINLDIDPVTGDSVINAAEAGGTVTLTGVVNGDVFSSGVVTLVINGVTYSTNVNPNGTWSVSVAGSDLSADSDRIVDASVVVTNGAGQQGTADSTESFIVKTSSRATIRVNSITSDDVVNAEESNSTITVSGRVGLDASAGDTVSMTINGTLYTTVVLANKTWSVGVSGSDLAQDNSFQVSVTGQDSAGNPYAGTTTSTHTVDTSADAGTVTVNAITSDDVINASEAAGTVAVSGTATGGDIAEGDTVTLEINGETYTTTVDANGEWSVDVAGSDLAADTAFDAVVTSSDAAGNTVDTTGSSTHTVDLE 5jth A 1.84 BS01 III B 1 E7 E11 F12 E14 A15 L18 M36 L39 M51 E54 V55 M71 M72 R74 M76 D80 E84 M109 E114 M124 E127 A128 F141 M144 M145 A147 E6 E10 F11 E13 A14 L17 M35 L38 M50 E53 V54 M70 M71 R73 M75 D79 E83 M108 E113 M123 E126 A127 F140 M143 M144 A146 P0DP25 DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPAFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 5juh A 1.35 BS01 CA A 1 D129 N131 V133 G135 D140 D109 N111 V113 G115 D120 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5juh A 1.35 BS02 CA A 2 D55 T56 D35 T36 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5juh A 1.35 BS03 CA A 3 G33 D36 D40 G13 D16 D20 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5juh A 1.35 BS04 CA A 4 D36 L38 D40 D63 D16 L18 D20 D43 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5juh A 1.35 BS05 CA A 5 G44 L45 E46 G47 D49 D73 G24 L25 E26 G27 D29 D53 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5juh A 1.35 BS06 CA A 6 G25 Q26 G27 D29 G44 L45 E46 D49 G5 Q6 G7 D9 G24 L25 E26 D29 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5juh A 1.35 BS07 CA A 7 E46 E72 E26 E52 A1YIY3 TLIGGQGDDVLFGGDDSLVDTLTGLEGSDIFILNDTTDVLNIDTITDFNAAEDALDLTDLLTGIAGSPGKDADVDAVTQFLTENVKVTDGHVKVGGEDVANFGSDSNFDSNGVDGVTTADSIKVIYNNEEYSINIDG 5kcx A 2.20 BS01 6S3 A 1 L44 V52 A65 I104 L120 E121 V126 L174 I185 L11 V19 A32 I71 L87 E88 V93 L141 I152 2.7.11.1 P11309 LESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5knr A 2.86 BS01 3L5 A 1 R47 G48 D104 I105 I106 D107 S108 G109 N110 T111 L112 K135 F156 V157 I162 D163 R43 G44 D95 I96 I97 D98 S99 G100 N101 T102 L103 K126 F147 V148 I153 D154 A0A0U4JN50 MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 5knr A 2.86 BS02 MG A 1 S49 E103 D104 S45 E94 D95 A0A0U4JN50 MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 5knr B 2.86 BS01 3L5 B 1 G48 E103 D104 I105 I106 D107 S108 G109 T111 K135 F156 V157 I162 D163 R169 G43 E93 D94 I95 I96 D97 S98 G99 T101 K125 F146 V147 I152 D153 R159 A0A0U4JN50 KHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILL 5kns A 2.79 BS01 3L7 A 1 R47 G48 I105 D107 S108 G109 N110 T111 K135 E155 F156 V157 I162 R169 R44 G45 I95 D97 S98 G99 N100 T101 K125 E145 F146 V147 I152 R159 A0A0U4JN50 DMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILL 5kns B 2.79 BS01 3L7 B 1 R47 D107 S108 G109 T111 K135 F156 V157 I162 D163 R169 R44 D98 S99 G100 T102 K126 F147 V148 I153 D154 R160 A0A0U4JN50 DMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 5knt A 2.55 BS01 6WB A 1 E103 D104 I105 D107 S108 G109 N110 T111 K135 E155 F156 V157 I162 E92 D93 I94 D96 S97 G98 N99 T100 K124 E144 F145 V146 I151 A0A0U4JN50 DMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILL 5knt B 2.55 BS01 6WB B 1 E103 D104 I105 I106 D107 S108 G109 N110 T111 K135 R138 F156 V157 I162 E94 D95 I96 I97 D98 S99 G100 N101 T102 K126 R129 F147 V148 I153 A0A0U4JN50 DMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILL 5knu A 2.81 BS01 6WA A 1 D107 S108 G109 T111 K135 F156 V157 I162 D163 D98 S99 G100 T102 K126 F147 V148 I153 D154 A0A0U4JN50 RDMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 5knu B 2.81 BS01 6WA B 1 S73 I105 I106 D107 S108 G109 L112 K135 R138 V157 I162 D163 S71 I98 I99 D100 S101 G102 L105 K128 R131 V150 I155 D156 A0A0U4JN50 RDMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILL 5knv A 2.86 BS01 6W9 A 1 I105 D107 G109 N110 T111 K135 R138 E155 V157 I162 D163 I94 D96 G98 N99 T100 K124 R127 E144 V146 I151 D152 A0A0U4JN50 MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILL 5knv B 2.86 BS01 6W9 B 1 I106 D107 S108 G109 N110 T111 L112 F156 V157 I162 D163 I96 D97 S98 G99 N100 T101 L102 F146 V147 I152 D153 A0A0U4JN50 DMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 5knx A 2.40 BS01 6WC A 1 S73 I105 I106 D107 S108 G109 N110 T111 K135 R138 E155 F156 V157 I162 D163 S69 I97 I98 D99 S100 G101 N102 T103 K127 R130 E147 F148 V149 I154 D155 A0A0U4JN50 MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGSTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVILLD 5knx B 2.40 BS01 6WC B 1 S73 I106 D107 S108 G109 N110 K135 E155 F156 V157 I162 D163 S70 I103 D104 S105 G106 N107 K132 E152 F153 V154 I159 D160 A0A0U4JN50 DMKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDYAQRYRHLPYIGKVIL 5kqv E 4.40 BS01 III B 1 F39 K40 F36 K37 2.7.10.1,2.7.10.1 P06213 23302862 PGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVGAKSDIIYVQTDATTFEDYLHNVVFV 5kqv F 4.40 BS02 FUC F 1 Y512 Q513 N514 Y499 Q500 N501 2.7.10.1,2.7.10.1 P06213 23302862 HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATTFEDYLHNVVFV 5ksq A 2.63 BS01 MN A 1 D8 D9 S40 N92 D8 D9 S40 N92 3.1.3.5 Q9PF20 28677327 MRVLVSNDDGVDAPGIKILADALRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTPTDCVHLALTGLLNYDPDIVVSGINNTGNLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTLAPQYETAAHAAINIVAQLKTDPLPADTILNVNVPDVTWQQMRGFKVTRLGNRHRSAPCLTQTDPRGHTIYWIGPAGPEQDAGPGTDFDAVRNTYISITPIHVDLTRYQALENVTRWTDRLTAHM 5ksr A 1.96 BS01 MN A 1 D8 D9 N92 N93 D8 D9 N92 N93 3.1.3.5 Q9PF20 28677327 MRVLVSNDDGVDAPGIKILADALRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTPTDCVHLALTGLLNYDPDIVVSGINNTGNLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTLYQAPQYETAAHAAINIVAQLKTDPLPADTILNVNVPDVTWQQMRGFKVTRLGNRHRSAPCLTQTDPRGHTIYWIGPAGPEQDAGPGTDFDAVRNTYISITPIHVDLTRYQALENVTRWTDRLTAHMD 5ksr B 1.96 BS01 MN B 1 D8 D9 N92 D8 D9 N92 3.1.3.5 Q9PF20 28677327 MRVLVSNDDGVDAPGIKILADALRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTPTDCVHLALTGLLNYDPDIVVSGINNTGNLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTLYAPQYETAAHAAINIVAQLKTDPLPADTILNVNVPDVTWQQMRGFKVTRLGNRHRSAPCLTQTDPRGHTIYWIGPAGPEQDAGPGTDFDAVRNTYISITPIHVDLTRYQALENVTRWTDRLTAHMD 5kss A 2.82 BS01 MN A 1 D8 D9 S40 N92 N93 D8 D9 S40 N92 N93 3.1.3.5 Q9PF20 28677327 MRVLVSNDDGVDAPGIKILADALRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTPTDCVHLALTGLLNYDPDIVVSGINNTGNLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTLYQQAPQYETAAHAAINIVAQLKTDPLPADTILNVNVPDVTWQQMRGFKVTRLGNRHRSAPCLTQTDPRGHTIYWIGPAGPEQDAGPGTDFDAVRNTYISITPIHVDLTRYQALENVTRWTDRLT 5kst C 2.76 BS01 MN C 1 D8 D9 S40 N92 N93 T106 D8 D9 S40 N92 N93 T106 3.1.3.5 Q9PF20 28677327 MRVLVSNDDGVDAPGIKILADALRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTPTDCVHLALTGLLNYDPDIVVSGINNTGNLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTLYRQAPQYETAAHAAINIVAQLKTDPLPADTILNVNVPDVTWQQMRGFKVTRLGNRHRSAPCLTQTDPRGHTIYWIGPAGPEQDAGPGTDFDAVRNTYISITPIHVDLTRYQALENVTRWTDRLTAH 5kvu A 2.66 BS01 NAP A 1 K84 P86 N87 S89 N137 R141 I350 A353 T564 A566 G586 G587 S588 A589 P590 H592 R603 W604 D605 R652 K80 P82 N83 S85 N132 R136 I345 A348 T559 A561 G581 G582 S583 A584 P585 H587 R598 W599 D600 R647 1.1.1.42 O53611 QPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTEEQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPTDQEKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRHGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEEQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLSDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIRAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSDMTTAVMRPSKTFNAALEAV 5kvu D 2.66 BS01 NAP D 1 K84 P86 N87 I88 S89 N137 I350 A353 T564 A566 G586 G587 S588 A589 P590 K591 H592 R603 W604 D605 R652 K80 P82 N83 I84 S85 N132 I340 A343 T554 A556 G576 G577 S578 A579 P580 K581 H582 R593 W594 D595 R642 1.1.1.42 O53611 QPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTEEQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPAPKTDQEKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRHGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEEQMQDAFETGVMFSLHVKATMPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLSDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIRAGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSDMTTAVMRPSKTFNAALEA 5m6o A 1.70 BS01 MAN A 1 G15 G16 L90 G138 D139 L140 D142 G15 G16 L90 G138 D139 L140 D142 28684550 MASQTITVGPWGGPGGNEWDDGSYTGIRIIELSYKEAIGSFSVIYDLNGEPFSGSKHTSKLPYTNVKIELQFPEEFLVSVSGYTAPFSSLATRTPVVRSLKFKTNKGRTFGPYGEEDGTYFNLPIENGLVVGFKGRTGDLLDAIGVHMAL 5m6o B 1.70 BS01 MAN B 1 G15 G16 G138 D139 L140 D142 G15 G16 G138 D139 L140 D142 28684550 MASQTITVGPWGGPGGNEWDDGSYTGIRIIELSYKEAIGSFSVIYDLNGEPFSGSKHTSKLPYTNVKIELQFPEEFLVSVSGYTAPFSSLATRTPVVRSLKFKTNKGRTFGPYGEEDGTYFNLPIENGLVVGFKGRTGDLLDAIGVHMAL 5m6o D 1.70 BS01 MAN D 1 G15 G16 L90 T94 G138 D139 L140 D142 G15 G16 L90 T94 G138 D139 L140 D142 28684550 MASQTITVGPWGGPGGNEWDDGSYTGIRIIELSYKEAIGSFSVIYDLNGEPFSGSKHTSKLPYTNVKIELQFPEEFLVSVSGYTAPFSSLATRTPVVRSLKFKTNKGRTFGPYGEEDGTYFNLPIENGLVVGFKGRTGDLLDAIGVHMAL 5m99 A 1.96 BS01 CA A 1 D411 D412 D415 F417 D387 D388 D391 F393 3.2.1.1 A0A059TXD8 28648523 NEVKYPVVYEIFIRSLYDSDGDGVGDINGVSQKVDYLRKLGIDAVWFMPFNEAVSYHGYDITDYYNVEKDYGTMEDLENMIQVLHENGIKVIMDLVINHTSDEHPWFKDAVENTTSSPYWDYYIMSLEDHSGQDHWHWKINSKGQKVWYFGLFGYNMPDLNHDSQKVREEVKKIVDFWISKGVDGFRIDAAKHIYGWSWDDGIQESAEYFEWFRDYVLSKKPDAILVGEVFSGNTYDLSLYPIPVFNFALMYSIRNYPEGQDGMIENNWVEESFLFLENHDLHRFFSHLQEHYKKFSESDYEFIKKRAALWYFLIFTLKGSPVIYYGGEIGTRGFKWHGPVYDEPVREPMQWYASGTGEGQTFWTKEVYKNAGITFGNADVDGCIYDDPYDGFSVEEQENDPKSLLNFIRFILNFRKDHDAILNGDQTIFRDWKNLIAFYRESSNEKLLVVLNPDPVWQNSFTFEENMTMILEVDFENFIWNESNVSFSAGESFTVDPMKAYIFKK 5mfd A 2.30 BS01 CA A 1 P275 E277 P264 E266 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd A 2.30 BS04 CA A 4 P65 N66 E67 P54 N55 E56 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd A 2.30 BS05 CA A 5 S208 G209 S250 S197 G198 S239 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd A 2.30 BS06 CA A 6 E240 W243 E282 E229 W232 E271 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd B 2.30 BS01 CA A 9 P114 R116 P96 R98 P03712 28691351 PTATAPGGLSAKAPAMTPLMLDTSSRKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAFAGTAISIVGSGSPKRKRKRKRK 5mfd C 2.30 BS01 CA C 1 G209 S250 G198 S239 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd E 2.30 BS05 CA E 5 D24 Q26 D13 Q15 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd E 2.30 BS09 CA E 9 P23 Q25 P12 Q14 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd E 2.30 BS10 CA F 1 E324 E327 E313 E316 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd F 2.30 BS01 CA F 1 E94 S111 G112 E76 S93 G94 P03712 28691351 PTATAPGGLSAKAPAMTPLMLDTSSRKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAFAGTAISIVGSGSPKRKRKRKRK 5mfd I 2.30 BS02 CA I 2 S82 S124 S71 S113 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd I 2.30 BS03 CA I 3 Q236 Q239 Q225 Q228 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd J 2.30 BS02 CA J 2 A81 S82 G83 I88 N121 S124 A70 S71 G72 I77 N110 S113 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQSH 5mfd K 2.30 BS05 CA K 5 W285 E324 E327 W274 E313 E316 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mfd K 2.30 BS06 CA K 6 Q236 Q239 E240 Q225 Q228 E229 28691351 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHENEKIQKEAQEALEKLQS 5mio C 3.19 BS01 MG C 1 T355 R456 S468 D492 T129 R222 S234 D258 Q99661 28694425 FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTAAPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDSKGIYAMASADVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKELDLGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKH 5mio C 3.19 BS02 ANP C 1 R266 P267 T350 G351 S352 G353 K354 T355 H356 D361 N464 S467 S468 A494 G495 R40 P41 T124 G125 S126 G127 K128 T129 H130 D135 N230 S233 S234 A260 G261 Q99661 28694425 FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTAAPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDSKGIYAMASADVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKELDLGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKH 5mka A 1.15 BS01 RCD A 1 D25 N55 G56 N59 K61 A78 D80 Q81 Q128 N162 Y164 W234 M343 W353 D11 N41 G42 N45 K47 A64 D66 Q67 Q114 N148 Y150 W220 M329 W339 B0L7B0 28370477 NVSGSVKLWVDTTQVPYYKKIVANFNKKYPDVKVKVTQSPNGSANAKTDVGKDPAKAADVFEVANDQLGSMAEAGYINPLSPDATKAVKNNNVAVASEGVTWKGKMFAYPFAEQAQTIYYNKSKLTADDVKTWDGLTAKGVLATDFTNAYNFYPVFLSAGTQLYGKTGETVKGTDVNSAKGEQAMAWFAQQKSNKGVMQTSNALNQLKSGKAAAILDGPWNSANIKKILGKNFAVAPYPTIKLDGKDVQMQAFLGIETFAVNSHASGSNQKAAATLASFITNKESQLIVYDHSGQIPVDKTAQKSSKVASDPVAGAVMTMAKPGNSTLMPKMPQMATFWNDAAPLINGAYTGSIPASQYSTKLDTFVKNISK 5mrm A 1.80 BS01 Q9T A 1 R157 Q158 V161 I177 A202 A203 Q238 V239 I240 L245 F249 S264 V266 E267 V273 R72 Q73 V76 I92 A117 A118 Q150 V151 I152 L157 F161 S176 V178 E179 V185 2.7.7.60 P69834 28686408 MEKSVSVILLAPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLSFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTKTLWEMQTPQVIKPELLKKGFELVKSEGLEVTDDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILS 5mro A 1.80 BS01 Q9P A 1 R157 I177 A203 Q238 V239 I240 L245 V259 D261 D262 V263 S264 I265 V266 V273 R73 I93 A119 Q154 V155 I156 L161 V175 D177 D178 V179 S180 I181 V182 V189 2.7.7.60 P69834 28686408 EKSVSVILLAGMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLSFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPELLKKGFELVKSEGLAVTDDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILS 5mrp A 1.90 BS01 6BC A 1 R157 Q158 I177 A203 Q238 V239 I240 V259 D261 D262 V263 S264 I265 V266 V273 R72 Q73 I92 A118 Q148 V149 I150 V169 D171 D172 V173 S174 I175 V176 V183 2.7.7.60 P69834 28686408 EKSVSVILLAGPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLSFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLWEMQTPQVIKPELLKKGFELVKSEGLAVTDDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILS 5mu0 A 2.70 BS01 III Q 1 D31 A32 W33 N53 L101 T102 F103 D104 D31 A32 W33 N53 L101 T102 F103 D104 28679953 EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRNKVNNHATNYAESVKGRFTISRDDSRSVVYLQMNNLKPEDTGIYYCTGLTFDYWGQGTTLTVSSAKTTAPSVYPLAPVCTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPALLLSGLYTLSSSVTVTSNTWPSQTITCNVAHPASSTKVDKKIEPRG 5mu0 B 2.70 BS01 III Q 1 N38 F50 Y53 S95 N38 F50 Y53 S95 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mu0 B 2.70 BS02 III Q 2 N31 Y32 I34 S36 N31 Y32 I34 S36 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mu0 E 2.70 BS01 III S 1 D31 A32 W33 L101 T102 F103 D104 D31 A32 W33 L101 T102 F103 D104 28679953 EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRNKVNNHATNYAESVKGRFTISRDDSRSVVYLQMNNLKPEDTGIYYCTGLTFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGGTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPALLLSGLYTLSSSVTVTSNTWPSQTITCNVAHPASSTKVDKKIEPRGP 5mu0 F 2.70 BS02 III S 2 Y32 I34 Y32 I34 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 5mu0 G 2.70 BS01 III T 1 D31 W33 N53 L101 T102 F103 D104 D31 W33 N53 L101 T102 F103 D104 28679953 EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRNKVNNHATNYAESVKGRFTISRDDSRSVVYLQMNNLKPEDTGIYYCTGLTFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPALLLSGLYTLSSSVTVTSNTWPSQTITCNVAHPASSTKVDKKIEPRG 5mu0 H 2.70 BS01 III T 1 N38 F50 S95 N38 F50 S95 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mu0 H 2.70 BS02 III T 2 Y32 I34 S36 Y32 I34 S36 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mu0 N 2.70 BS02 III W 2 I34 S36 I34 S36 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNR 5mu0 P 2.70 BS02 III X 2 N31 Y32 S95 N31 Y32 S95 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 5mu2 A 2.70 BS01 III X 1 D31 W33 L101 T102 F103 D104 D31 W33 L101 T102 F103 D104 28679953 EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRNKVNNHATNYAESVKGRFTISRDDSRSVVYLQMNNLKPEDTGIYYCTGLTFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPALLLSGLYTLSSSVTVTSNTWPSQTITCNVAHPASSTKVDKKIEPRGP 5mu2 B 2.70 BS01 III X 1 N38 F50 Y53 S95 Y100 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5mu2 D 2.70 BS01 III Q 1 Y32 N38 F50 Y53 S95 Y100 Y32 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5mu2 K 2.70 BS01 III U 1 D31 A32 W33 V55 N56 L101 T102 F103 D104 D31 A32 W33 V55 N56 L101 T102 F103 D104 28679953 EVKLEESGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRNKVNNHATNYAESVKGRFTISRDDSRSVVYLQMNNLKPEDTGIYYCTGLTFDYWGQGTTLTVSSAKTTAPSVYPLAPVCGTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPALLLSGLYTLSSSVTVTSNTWPSQTITCNVAHPASSTKVDKKIEPRGP 5mu2 N 2.70 BS01 III V 1 Y32 I34 S36 N38 F50 Y53 S95 Y100 Y32 I34 S36 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5mu2 P 2.70 BS01 III W 1 N31 I34 N38 F50 Y53 S95 Y100 N31 I34 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mub P 3.10 BS02 PRO Q 1 N31 S36 N31 S36 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mue A 2.40 BS01 VIV A 1 I119 V132 F133 S136 S140 I154 F158 W163 I179 V182 L183 F187 I72 V85 F86 S89 S93 I107 F111 W116 I132 V135 L136 F140 P49638 28694484 TDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISE 5mug A 2.42 BS01 VIV A 1 I119 V132 S136 L137 S140 I154 F158 W163 I179 V182 L183 F187 I72 V85 S89 L90 S93 I107 F111 W116 I132 V135 L136 F140 P49638 28694484 TDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ 5mv3 D 2.95 BS01 III E 1 Y32 N38 F50 Y53 S95 Y32 N38 F50 Y53 S95 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mv3 G 2.95 BS01 III H 1 I34 N38 F50 Y53 S95 Y100 I34 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mv4 B 2.90 BS01 III X 1 N31 Y32 I34 S36 N38 F50 Y53 S95 Y100 N31 Y32 I34 S36 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mv4 D 2.90 BS01 III E 1 N31 Y32 I34 S36 N38 F50 Y53 S95 N31 Y32 I34 S36 N38 F50 Y53 S95 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5mv4 M 2.90 BS01 III N 1 Y32 I34 N38 F50 Y53 S95 Y100 Y32 I34 N38 F50 Y53 S95 Y100 28679953 DIVLTQSPASLAVSLGQRATISCRASESVDNYGISSMNWFQQKAGQPPKFLIYAASKQGSGVPARFSGSGSGTDFSLIIHPVEEDDTAVYFCQQSKGVPYTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 5n5r A 1.80 BS01 III P 1 N42 S45 V46 K49 R56 F119 K122 R129 Y130 P167 I168 G171 L174 N175 V178 E182 D215 I219 L222 D225 N226 W230 N47 S50 V51 K54 R61 F118 K121 R128 Y129 P166 I167 G170 L173 N174 V177 E181 D214 I218 L221 D224 N225 W229 P31947 28681606 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5n5r A 1.80 BS02 NV1 A 1 F198 L205 Y213 T217 M220 Q221 F197 L204 Y212 T216 M219 Q220 P31947 28681606 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5n5t A 1.80 BS01 III P 1 N42 S45 V46 K49 R56 F119 K122 R129 Y130 P167 I168 G171 L174 N175 V178 E182 I219 L222 N226 W230 N47 S50 V51 K54 R61 F118 K121 R128 Y129 P164 I165 G168 L171 N172 V175 E179 I216 L219 N223 W227 P31947 28681606 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5n5t A 1.80 BS02 8OB A 1 I191 K195 F198 R224 L227 T231 I188 K192 F195 R221 L224 T228 P31947 28681606 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5n5w A 1.37 BS02 8OE A 1 K195 F198 R224 L227 T231 K193 F196 R222 L225 T229 P31947 28681606 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5n75 A 1.80 BS02 MG A 1 D215 I219 D218 I222 P31947 28681606 GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNESEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 5nhy A 1.72 BS01 8XT A 1 L9 F27 N33 G34 F72 M81 M116 W117 D119 D120 W123 F124 L7 F25 N31 G32 F70 M79 M114 W115 D117 D118 W121 F122 3.6.1.55,3.6.1.56 P36639 28679043 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 5nog A 11.00 BS01 ADP A 1 S14 G15 L16 K18 G156 D157 E214 G302 M305 Y306 K336 S10 G11 L12 K14 G152 D153 E210 G298 M301 Y302 K332 B6VNT8 28607071 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVH 5nog C 11.00 BS01 ADP C 1 S14 G15 L16 K18 G156 D157 R210 K213 E214 G302 M305 Y306 K336 S10 G11 L12 K14 G152 D153 R206 K209 E210 G298 M301 Y302 K332 B6VNT8 28607071 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVH 5nuv A 1.55 BS01 BU3 A 1 K347 W349 F358 K41 W43 F52 Q676U5 28685931 EVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGAACEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQP 5o09 A 3.60 BS01 GDP A 1 Q13 A14 Q17 D72 A142 G145 G146 T147 G148 S181 E185 N208 V226 N230 I233 Q11 A12 Q15 D70 A140 G143 G144 T145 G146 S179 E183 N206 V224 N228 I231 28673988 VNNTIVVSIGQAGNQIAASFWKTVCLEHGIDPLTGQTAPGVAPRGNWSSFFSKLGESSSGSYVPRAIMVDLEPSVIDNVKATSGSLFNPANLISRTEGAGGNFAVGYLGAGREVLPEVMSRLDYEIDKCDNVGGIIVLHAIGGGTGSGFGALLIESLKEKYGEIPVLSCAVLPSPQVSSVVTEPYNTVFALNTLRRSADACLIFDNEALFDLAHRKWNIESPTVDDLNLLITEALAGITASMRFSGFLTVEITLRELLTNLVPQPSLHFLMCAFAPLTPPDRSKFEELGIEEMIKSLFDNGSVFAACSPMEGRFLSTAVLYRGIMEDKPLADAALAAMREKLPLTYWIPTAFKIGYVEQPGISHRKSMVLLANNTEIARVLDRICHNFDKLWQRKAFANWYLNEGMSEEQINVLRASAQELVQSYQVAEESGA 5o09 B 3.60 BS01 GDP B 1 G10 Q11 C12 Q15 N100 S139 G142 G143 S144 G145 D178 E182 N205 Y222 N226 I229 G9 Q10 C11 Q14 N91 S130 G133 G134 S135 G136 D169 E173 N196 Y213 N217 I220 28673988 REILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKSNMEVFFHKVRDGKYVPRAVLVDLEPGVIARIEGGDMSQLFDESSIVRKIPGAANNWARGYNVEGEKVIDQIMNVIDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSPLISDSAVEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLNRSPNYMDLNNIIALIVSSVTASLRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMQVRTNFPDLARETFAQDNFTAAIDWQQGVYLAASALFRGDVKAKDVDENMATIRKSLNYASYMPASGGLKLGYAETAPEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSRDMMAKARNQIATLAQSYRDAS 5o09 B 3.60 BS02 GDP A 2 L246 E252 L237 E243 28673988 REILSIHVGQCGNQIADSFWRLALREHGLTEAGTLKSNMEVFFHKVRDGKYVPRAVLVDLEPGVIARIEGGDMSQLFDESSIVRKIPGAANNWARGYNVEGEKVIDQIMNVIDSAVEKTKGLQGFLMTHSIGGGSGSGLGSLILERLRQAYPKKRIFTFSVVPSPLISDSAVEPYNAILTLQRILDNADGAVLLDNEALFRIAKAKLNRSPNYMDLNNIIALIVSSVTASLRFPGKLNTDLSEFVTNLVPFPGNHFLTASFAPMQVRTNFPDLARETFAQDNFTAAIDWQQGVYLAASALFRGDVKAKDVDENMATIRKSLNYASYMPASGGLKLGYAETAPEGFASSGLALVNHTGIAAVFERLIAQFDIMFDNHAYTHWYENAGVSRDMMAKARNQIATLAQSYRDAS 5o4h A 1.75 BS01 SAH A 1 K29 G49 Y51 L52 S53 D72 I73 Q74 L77 L91 L112 T113 G117 V118 E134 G176 T177 F213 K26 G46 Y48 L49 S50 D69 I70 Q71 L74 L88 L109 T110 G114 V115 E131 G173 T174 F210 Q6LX54 28682478 GITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKL 5o4j A 1.70 BS02 PJL A 1 T113 G114 I115 G176 M178 T179 T113 G114 I115 G176 M178 T179 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4j A 1.70 BS03 9KH B 1 I5 V9 L199 I5 V9 L199 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4j B 1.70 BS03 9KH B 1 T113 G114 I115 T174 G176 M178 T179 T113 G114 I115 T174 G176 M178 T179 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFD 5o4j C 1.70 BS02 9KH C 1 T113 G114 I115 P136 T174 G176 M178 T179 T112 G113 I114 P135 T173 G175 M177 T178 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKL 5o4m A 2.10 BS03 MPD A 1 V22 S23 L52 S55 I80 F82 V21 S22 L51 S54 I79 F81 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4m B 2.10 BS04 MPD B 1 K19 V22 S23 L52 S55 I80 F82 K19 V22 S23 L52 S55 I80 F82 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKL 5o4m C 2.10 BS03 MPD C 1 K19 S23 L52 L222 K18 S22 L51 L221 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4m C 2.10 BS04 9KH D 1 I5 L199 I4 L198 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4m D 2.10 BS03 9KH D 1 G114 I115 P136 T174 G176 M178 T179 G113 I114 P135 T173 G175 M177 T178 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDK 5o4m D 2.10 BS04 MPD D 1 S23 L52 I80 S22 L51 I79 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDK 5o4n A 2.05 BS03 MPD A 1 I16 D20 D24 I250 I16 D20 D24 I250 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4n A 2.05 BS04 MPD A 2 K19 V22 S23 L52 F82 L225 K19 V22 S23 L52 F82 L225 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFDKLA 5o4n B 2.05 BS04 MPD B 1 V22 S23 L52 S55 F82 L225 V22 S23 L52 S55 F82 L225 Q6LX54 28682478 MNYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEF 5o4n C 2.05 BS03 MPD C 1 K19 V22 S23 I80 L225 K18 V21 S22 I79 L224 Q6LX54 28682478 NYGITESVKTTRSKIKIKDIVSDVVEKKANAIKYFLEGEEFKQAIVFGAYLSGSYIAYSLLKDCEEVIIVDIQPHLKDILFNDGIKFMDLNKLQLELRNGTSINPDLVIDLTGIGGVSPDLISKFNPKVLIVEDPKGNHDKGISKIDNTDKRLCVGAKKGVLKTYRSSKFSKTSGTMTLVVDIIMDSCREINELDSVLYTIPNLKYFEGTVFHEKNVKKFLTELNMSAITVSSIDHVEYELEEILSKNISRVDSFVKEFD 5sw3 A 1.38 BS03 46L A 2 M75 H133 M134 E142 I143 L146 M65 H120 M121 E129 I130 L133 2.4.2.29 P28720 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHLRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFAR 5t7x A 2.35 BS01 NUC C 1 W464 F465 K467 H468 R469 G470 Q471 G472 G473 K514 Y518 R521 R522 P535 L536 R538 C560 W4 F5 K7 H8 R9 G10 Q11 G12 G13 K54 Y58 R61 R62 P75 L76 R78 C100 Q3KSS4 28077791 KGGWFGKHRGQGGSNPKFENIAEGLRVLLARSHVERTTEEGNWVAGVFVYGGSKTSLYNLRRGIALAVPQCRITPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMIKPAPTCNIKVTVCSFDDGVDLP 5t7x A 2.35 BS02 NUC D 1 G462 G463 W464 H468 R469 K477 S513 T515 S516 N519 K586 P589 T590 G2 G3 W4 H8 R9 K17 S53 T55 S56 N59 K126 P129 T130 Q3KSS4 28077791 KGGWFGKHRGQGGSNPKFENIAEGLRVLLARSHVERTTEEGNWVAGVFVYGGSKTSLYNLRRGIALAVPQCRITPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMIKPAPTCNIKVTVCSFDDGVDLP 5t7x B 2.35 BS02 NUC D 1 R459 K460 K461 F465 K467 H468 R469 G470 Q471 G472 G473 K514 Y518 R521 R522 P535 L536 R538 C560 R1 K2 K3 F7 K9 H10 R11 G12 Q13 G14 G15 K56 Y60 R63 R64 P77 L78 R80 C102 Q3KSS4 28077791 RKKGGWFGKHRGQGGSNPKFENIAEGLRVLLARSHVERTTEEGNWVAGVFVYGGSKTSLYNLRRGIALAVPQCRITPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMIKPAPTCNIKVTVCSFDDGVDLP 5tqz D 1.60 BS01 GLC D 1 G15 G16 T94 G138 D139 L140 D142 G15 G16 T94 G138 D139 L140 D142 28684550 MASQTITVGPWGGPGGNEWDDGSYTGIRIIELSYKEAIGSFSVIYDLNGEPFSGSKHTSKLPYTNVKIELQFPEEFLVSVSGYTAPFSSLATRTPVVRSLKFKTNKGRTFGPYGEEDGTYFNLPIENGLVVGFKGRTGDLLDAIGVHMAL 5u98 A 2.00 BS01 III C 1 M5 Y7 Y9 M45 E63 N66 M67 A69 S70 T73 N77 I80 Y84 Y99 T143 W147 V152 Q155 Y159 W167 Y171 M4 Y6 Y8 M44 E62 N65 M66 A68 S69 T72 N76 I79 Y83 Y98 T142 W146 V151 Q154 Y158 W166 Y170 P18465 28686208 SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 5u98 D 2.00 BS01 III F 1 M5 Y7 Y9 M45 E63 N66 M67 S70 T73 E76 N77 I80 Y84 Y99 T143 K146 W147 V152 Q155 Y159 W167 Y171 M4 Y6 Y8 M44 E62 N65 M66 S69 T72 E75 N76 I79 Y83 Y98 T142 K145 W146 V151 Q154 Y158 W166 Y170 P18465 28686208 SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPEYWDGETRNMKASAQTYRENLRIALRYYNQSEAGSHIIQVMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 5ue2 A BS01 CA A 1 D133 I134 G165 L166 G167 G168 D169 D133 I134 G165 L166 G167 G168 D169 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue2 A BS02 CA A 2 F149 D150 G151 P152 G153 N154 T155 D173 E176 F149 D150 G151 P152 G153 N154 T155 D173 E176 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue2 A BS03 ZN A 1 H143 D145 H158 H171 H143 D145 H158 H171 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue2 A BS05 SGN A 1 E13 D17 R21 Y25 E13 D17 R21 Y25 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue2 A BS06 IDS A 1 Q14 R21 Q14 R21 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue2 A BS07 IDS A 2 F149 D150 G151 F149 D150 G151 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue5 A BS05 SGN A 1 Y91 S110 N114 F124 R125 K126 Y91 S110 N114 F124 R125 K126 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue5 A BS06 IDS A 1 Y91 D106 K126 Y91 D106 K126 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue5 A BS07 SGN A 2 I103 D106 R107 I103 D106 R107 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5ue5 A BS08 IDS A 2 Y96 P101 H102 Y96 P101 H102 3.4.24.23 P09237 28648610 PQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHALGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK 5urj A 2.75 BS01 8LS A 1 T1197 H1235 F1254 F1255 V1256 P1257 D1678 Y1679 P1680 I1681 Y1682 S1709 K1710 D1712 F1713 K1716 F1717 P1723 T788 H826 F845 F846 V847 P848 D1269 Y1270 P1271 I1272 Y1273 S1300 K1301 D1303 F1304 K1307 F1308 P1314 3.6.4.13 O75643 28586220 LAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDESVFDIDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFS 5urk A 2.95 BS01 8LP A 1 H1235 F1254 F1255 P1257 D1678 Y1679 P1680 I1681 S1709 K1710 D1712 F1713 L1722 P1723 H828 F847 F848 P850 D1271 Y1272 P1273 I1274 S1302 K1303 D1305 F1306 L1315 P1316 3.6.4.13 O75643 28586220 LAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTESVFDIERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFS 5urm A 2.80 BS01 8LV A 1 M544 R545 S546 T589 E591 K592 I595 T814 M141 R142 S143 T186 E188 K189 I192 T411 3.6.4.13 O75643 28586220 APRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVD 5urm B 2.80 BS01 8LV B 1 M544 R545 T589 E591 K592 I595 A813 T814 M138 R139 T183 E185 K186 I189 A396 T397 3.6.4.13 O75643 28586220 APRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREEVLRTEAEQCKNLELKDLLPFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSVFDIMEMEDEERNLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVD 5uuf A 1.61 BS02 NUC C 1 Q38 T39 P40 R43 R215 Q38 T39 P40 R43 R215 C2T7T7 MHPFVKALQEHFTAHQNPEKAEPMARYMKNHFLFLGIQTPERRQLLKDIIQIHTLPDQKDFQIIIRELWDLPEREFQAAALDIMQKYKKHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHPELISAYIPKWIASDNIWLQRAAILFQLKYKQKMDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQNNELAPLSKREAIKHIKQNYG 5uuf A 1.61 BS03 YTA B 1 K20 P23 M24 Y27 M28 Q38 W109 D113 P117 L155 K156 W187 K20 P23 M24 Y27 M28 Q38 W109 D113 P117 L155 K156 W187 C2T7T7 MHPFVKALQEHFTAHQNPEKAEPMARYMKNHFLFLGIQTPERRQLLKDIIQIHTLPDQKDFQIIIRELWDLPEREFQAAALDIMQKYKKHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHPELISAYIPKWIASDNIWLQRAAILFQLKYKQKMDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQNNELAPLSKREAIKHIKQNYG 5uug A 1.71 BS02 NUC C 1 Q38 T39 P40 R43 K156 Q40 T41 P42 R45 K158 C2T7T7 VPMHPFVKALQEHFTAHQNPEKAEPMARYMKNHFLFLGIQTPERRQLLKDIIQIHTLPDQKDFQIIIRELWDLPEREFQAAALDIMQKYKKHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHPELISAYIPKWIASDNIWLQRAAILFQLKYKQKMDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQNNELAPLSKREAIKHIKQNY 5uug A 1.71 BS03 CA A 1 K183 E216 K185 E218 C2T7T7 VPMHPFVKALQEHFTAHQNPEKAEPMARYMKNHFLFLGIQTPERRQLLKDIIQIHTLPDQKDFQIIIRELWDLPEREFQAAALDIMQKYKKHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHPELISAYIPKWIASDNIWLQRAAILFQLKYKQKMDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQNNELAPLSKREAIKHIKQNY 5uug A 1.71 BS04 YTA B 1 P23 M24 Y27 M28 Q38 W109 D110 L155 K156 W187 P25 M26 Y29 M30 Q40 W111 D112 L157 K158 W189 C2T7T7 VPMHPFVKALQEHFTAHQNPEKAEPMARYMKNHFLFLGIQTPERRQLLKDIIQIHTLPDQKDFQIIIRELWDLPEREFQAAALDIMQKYKKHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHPELISAYIPKWIASDNIWLQRAAILFQLKYKQKMDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQNNELAPLSKREAIKHIKQNY 5uuh A 1.57 BS04 YTA B 1 M24 Y27 M28 Q38 W109 D110 L155 K156 W187 M24 Y27 M28 Q38 W109 D110 L155 K156 W187 C2T7T7 MHPFVKALQEHFTAHQNPEKAEPMARYMKNHFLFLGIQTPERRQLLKDIIQIHTLPDQKDFQIIIRELWDLPEREFQAAALDIMQKYKKHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHPELISAYIPKWIASDNIWLQRAAILFQLKYKQKMDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQNNELAPLSKREAIKHIKQNY 5v2p A 2.00 BS01 III B 1 M295 M296 K298 A299 L300 K393 I394 S396 K398 V399 R402 L403 S406 E440 N441 L443 A446 M136 M137 K139 A140 L141 K215 I216 S218 K220 V221 R224 L225 S228 E262 N263 L265 A268 Q8VGC3 28278376 SSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPS 5v2q A 1.70 BS01 III B 1 M295 M296 K298 A299 K393 I394 S396 K398 V399 L403 S406 R407 E440 N441 Q442 L443 A446 M129 M130 K132 A133 K215 I216 S218 K220 V221 L225 S228 R229 E262 N263 Q264 L265 A268 Q8VGC3 28278376 AVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKFFKTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRT 5ve3 B 1.79 BS01 FE B 1 H58 H114 D133 H61 H117 D136 1.13.11.18,2.8.1.1 B2TEQ2 28684420 GSHMLIFRQLFDQQSSTYTYLLADSTTREAVLIDPVFEQVRRDAALIEELGLHLLYTIDTHVHADHVTGAWMLNRRIGSRIAISAASGAEGADRYLSHGDKVEFGTRYLTVRATPGHTDGCITLVLDNETMAFTGDCLLIRGTGRTDFQRGDAHTMFRAVHGQIFTLPTACLLYPAHDYRGLTVTSVGEERRFNPRLGGELCEEDFTGYMTNLHLPHPKQIDVAVPANLKCGLAEPDWAPLTCSFAGIWEINAQWLEENLRAVEIVDVREPEEFNGPLGRIPAARLISLGELAGRTAELTKDRPIVTVCRAGGRSAQATVMLRQAGFERVANLPGGMLRWRAEGRVVE 5ve5 A 2.35 BS02 GSH A 1 H114 D133 T140 G141 R142 Y176 L212 P215 K216 H116 D135 T142 G143 R144 Y178 L214 P217 K218 1.13.11.18,2.8.1.1 B2TEQ2 28684420 SHMLIFRQLFDQQSSTYTYLLADSTTREAVLIDPVFEQVRRDAALIEELGLHLLYTIDTHVHADHVTGAWMLNRRIGSRIAISAASGAEGADRYLSHGDKVEFGTRYLTVRATPGHTDGCITLVLDNETMAFTGDCLLIRGTGRTDFQRGDAHTMFRAVHGQIFTLPTACLLYPAHDYRGLTVTSVGEERRFNPRLGGELCEEDFTGYMTNLHLPHPKQIDVAVPANLKCGLAEPDWAPLTCSFAGIWEINAQWLEENLRAVEIVDVREPEEFNGPLGRIPAARLISLGELAGRTAELTKDRPIVTVSRAGGRSAQATVMLRQAGFERVANLPGGMLRWRAEGRVVENGS 5ve5 B 2.35 BS02 GSH B 1 H114 D133 L136 G141 R142 Y176 H116 D135 L138 G143 R144 Y178 1.13.11.18,2.8.1.1 B2TEQ2 28684420 SHMLIFRQLFDQQSSTYTYLLADSTTREAVLIDPVFEQVRRDAALIEELGLHLLYTIDTHVHADHVTGAWMLNRRIGSRIAISAASGAEGADRYLSHGDKVEFGTRYLTVRATPGHTDGCITLVLDNETMAFTGDCLLIRGTGRTDFQRGDAHTMFRAVHGQIFTLPTACLLYPAHDYRGLTVTSVGEERRFNPRLGGELCEEDFTGYMTNLHLPHPKQIDVAVPANLKCGLAAPDWAPLTCSFAGIWEINAQWLEENLRAVEIVDVREPEEFNGPLGRIPAARLISLGELAGRTAELTKDRPIVTVSRAGGRSAQATVMLRQAGFERVANLPGGMLRWRAEGRVVENG 5ve5 C 2.35 BS02 GSH C 1 D62 D133 L136 T140 G141 R142 Y176 P215 K216 D63 D134 L137 T141 G142 R143 Y177 P216 K217 1.13.11.18,2.8.1.1 B2TEQ2 28684420 HMLIFRQLFDQQSSTYTYLLADSTTREAVLIDPVFEQVRRDAALIEELGLHLLYTIDTHVHADHVTGAWMLNRRIGSRIAISAASGAEGADRYLSHGDKVEFGTRYLTVRATPGHTDGCITLVLDNETMAFTGDCLLIRGTGRTDFQRGDAHTMFRAVHGQIFTLPTACLLYPAHDYRGLTVTSVGEERRFNPRLGGELCEEDFTGYMTNLHLPHPKQIDVAVPANLKCGLPDWAPLTCSFAGIWEINAQWLEENLRAVEIVDVREPEEFNGPLGRIPAARLISLGELAGRTAELTKDRPIVTVSRAGGRSAQATVMLRQAGFERVANLPGGMLRWRAEGRVVENGS 5vej A 1.30 BS03 F A 1 H55 K169 H230 D301 H22 K136 H197 D268 Q93LD7 28673485 GDLINTVRGPIPVSEAGFTLTHEHICGSSAGFLRAWPEFFGSRKALAEKAVRGLRHARSAGVQTIVDVSTFDIGRDVRLLAEVSRAADVHIVAATGLWFDPPLSMRMRSVEELTQFFLREIQHGIEDTGIRAGIIKVATTGKATPFQELVLKAAARASLATGVPVTTHTSASQRDGEQQAAIFESEGLSPSRVCIGHSDDTDDLSYLTGLAARGYLVGLDRMPYSAIGLEGNASALALFGTRSWQTRALLIKALIDRGYKDRILVSHDWLFGFSSYVTNIMDVMDRINPDGMAFVPLRVIPFLREKGVPPETLAGVTVANPARFLSPT 5vj7 A 2.55 BS01 SF4 A 1 C56 I60 T97 C101 Q103 Q106 C107 I122 E126 I454 C52 I56 T93 C97 Q99 Q102 C103 I118 E122 I443 I6V148 IKERVPTPERSVGERVRDFGEVNLGYSWELALREAERCLQCPVEYAPCIKGCPVHINIPGFIKALRENRDNPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIGKLERFVADYAREHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLTYGIPEFRLPKEILRKELKKLSLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPKLPNIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKKVVVIGAGNTAMDAARSALRLGAEVTIAYRRGREDMTARIEEVKHAEEEGVKFMFFVNPVEFIGDENGNVKAVKFEKMKPGKRKIVGTGEYITVEADTVIIAIGQTPNKVLWRATPELKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHQYLSK 5vj7 A 2.55 BS02 SF4 A 2 C42 L43 C45 C52 I62 C111 V112 V113 I120 C38 L39 C41 C48 I58 C107 V108 V109 I116 I6V148 IKERVPTPERSVGERVRDFGEVNLGYSWELALREAERCLQCPVEYAPCIKGCPVHINIPGFIKALRENRDNPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIGKLERFVADYAREHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLTYGIPEFRLPKEILRKELKKLSLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPKLPNIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKKVVVIGAGNTAMDAARSALRLGAEVTIAYRRGREDMTARIEEVKHAEEEGVKFMFFVNPVEFIGDENGNVKAVKFEKMKPGKRKIVGTGEYITVEADTVIIAIGQTPNKVLWRATPELKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHQYLSK 5vj7 A 2.55 BS03 FAD A 1 V100 I160 G161 A162 G163 P164 A165 E184 A185 L186 G191 V192 Y195 G196 I197 R201 H225 V227 G246 T247 G248 N269 L272 N303 T304 D307 R333 Q406 L412 G444 D445 A451 T452 V453 A456 V96 I156 G157 A158 G159 P160 A161 E180 A181 L182 G187 V188 Y191 G192 I193 R197 H221 V223 G242 T243 G244 N265 L268 N299 T300 D303 R329 Q395 L401 G433 D434 A440 T441 V442 A445 I6V148 IKERVPTPERSVGERVRDFGEVNLGYSWELALREAERCLQCPVEYAPCIKGCPVHINIPGFIKALRENRDNPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIGKLERFVADYAREHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLTYGIPEFRLPKEILRKELKKLSLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPKLPNIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKKVVVIGAGNTAMDAARSALRLGAEVTIAYRRGREDMTARIEEVKHAEEEGVKFMFFVNPVEFIGDENGNVKAVKFEKMKPGKRKIVGTGEYITVEADTVIIAIGQTPNKVLWRATPELKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAIHQYLSK 5vj7 B 2.55 BS01 FAD B 1 F33 E43 I45 P46 L47 T48 I62 V63 F64 R66 G67 T69 T70 E113 D218 L219 H220 P221 I222 M223 P249 V265 E272 F33 E43 I45 P46 L47 T48 I62 V63 F64 R66 G67 T69 T70 E113 D217 L218 H219 P220 I221 M222 P248 V264 E271 1.18.1.2 I6TYZ3 MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIVLIVFTRGKTTMRMAVELKEGDSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKAWQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLNPNQDFLANKNVSQRLKEKVRELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGEVKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEEL 5vj7 B 2.55 BS02 FES B 1 M223 V224 D225 G226 G228 M229 C230 G231 C233 C245 M222 V223 D224 G225 G227 M228 C229 G230 C232 C244 1.18.1.2 I6TYZ3 MYKILEKKEIAMRNTWYKVYAPHVAKKVQPGQFVIVRAFPNGERIPLTPVMWDREEGWIVLIVFTRGKTTMRMAVELKEGDSLLNVAGPLGTPVPMEKFGKILAIGAYTGIVEVYPIAKAWQEIGNDVTTLHVTFEPMVILKEELEKAVTRHIVEPVPLNPNQDFLANKNVSQRLKEKVRELLESEDWDLVFMVGPVGDQKQVFEVVKEYGVPMKVDLHPIMVDGTGMCGACRVTVGGEVKFACVDGPEFDAYQVDWDELIHRVGFYAKLEKLALEKYMEEL 5vol A 1.98 BS01 CA A 1 D234 D235 D262 D208 D209 D236 B3CET1 28669823 NFQSKVVTDTLFSKVLNSKRAYTVFLPKSFEQNKEKKYPVLYLLHGMWETNPVWAERGHVKDVMDRLVASGEACEMIIVTPNAGGNIHLEWNGYFDMPGWKYETFFYTEFLPYIEKKYRVIGDRQHRAIAGLSMGGGGATNYGQRHSDMFCAVYAMSALMSIPEDPNSKIAILTRSVIENSCVKYVMEADEDRKADLRSVAWFVDCGDDDFLLDRNIEFYQAMRNAGVPCQFRVRDGGHDWEYWHSALYQCLPFVTRIFG 5vol A 1.98 BS02 CA B 1 Q257 R259 Q231 R233 B3CET1 28669823 NFQSKVVTDTLFSKVLNSKRAYTVFLPKSFEQNKEKKYPVLYLLHGMWETNPVWAERGHVKDVMDRLVASGEACEMIIVTPNAGGNIHLEWNGYFDMPGWKYETFFYTEFLPYIEKKYRVIGDRQHRAIAGLSMGGGGATNYGQRHSDMFCAVYAMSALMSIPEDPNSKIAILTRSVIENSCVKYVMEADEDRKADLRSVAWFVDCGDDDFLLDRNIEFYQAMRNAGVPCQFRVRDGGHDWEYWHSALYQCLPFVTRIFG 5vr8 A 2.00 BS01 UDX A 1 G11 G13 Y14 V15 D36 V37 R41 V89 N90 T91 Y108 S130 T131 V132 S275 R346 G11 G13 Y14 V15 D36 V37 R41 V89 N90 T91 Y108 S130 T131 V132 S275 R346 1.1.1.22 O60701 MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKK 5vr8 C 2.00 BS01 ADP C 1 I10 G11 G13 Y14 V15 D36 V37 R41 V89 N90 C112 R346 I11 G12 G14 Y15 V16 D37 V38 R42 V90 N91 C113 R347 1.1.1.22 O60701 HMFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKK 5vrw A 2.58 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 R258 Y271 R283 L287 T292 I293 N294 E295 Y296 R299 H26 S219 K220 G221 E222 T223 K224 R248 Y261 R273 L277 T282 I283 N284 E285 Y286 R289 2.7.7.7,4.2.99.- P06746 28682600 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vrw A 2.58 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 D192 M236 R254 D256 Y271 S96 G97 G99 P100 S101 A102 D184 M226 R244 D246 Y261 2.7.7.7,4.2.99.- P06746 28682600 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vrw A 2.58 BS05 CA P 2 T101 V103 S104 G105 I106 T93 V95 S96 G97 I98 2.7.7.7,4.2.99.- P06746 28682600 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vry A 1.90 BS02 NUC P 1 S104 G105 I106 G107 P108 S109 A110 G179 D190 D192 R254 D256 Y271 F272 T273 G274 D276 N279 S96 G97 I98 G99 P100 S101 A102 G171 D182 D184 R246 D248 Y263 F264 T265 G266 D268 N271 2.7.7.7,4.2.99.- P06746 28682600 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vry A 1.90 BS07 MG P 3 T101 V103 S104 I106 T93 V95 S96 I98 2.7.7.7,4.2.99.- P06746 28682600 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vrz A 2.05 BS02 NUC P 1 V103 S104 G105 G107 P108 S109 A110 R183 D190 D192 R254 D256 Y271 F272 T273 G274 D276 N279 V94 S95 G96 G98 P99 S100 A101 R174 D181 D183 R245 D247 Y262 F263 T264 G265 D267 N270 2.7.7.7,4.2.99.- P06746 28682600 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vs1 A 2.50 BS06 TTP P 1 R149 S180 R183 G189 D190 D192 Y271 F272 T273 G274 S275 D276 N279 R140 S171 R174 G180 D181 D183 Y262 F263 T264 G265 S266 D267 N270 2.7.7.7,4.2.99.- P06746 28682600 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vs1 A 2.50 BS07 CA D 1 K60 L62 P63 V65 K51 L53 P54 V56 2.7.7.7,4.2.99.- P06746 28682600 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vs1 A 2.50 BS08 CA A 1 G179 D190 D192 G170 D181 D183 2.7.7.7,4.2.99.- P06746 28682600 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vs4 A 1.87 BS03 NUC D 1 K35 A38 Y39 P63 G64 V65 G66 K68 I69 E288 K27 A30 Y31 P55 G56 V57 G58 K60 I61 E280 2.7.7.7,4.2.99.- P06746 28682600 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 5vse A 1.60 BS06 9HG A 1 D1074 A1077 D1078 R1080 D1083 L1086 D1088 V1096 C1098 R1157 F1158 I1161 K1162 D156 A159 D160 R162 D165 L168 D170 V175 C177 R236 F237 I240 K241 2.1.1.-,2.1.1.43 Q96KQ7 28662962 EKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSRLA 5vy9 A 4.00 BS01 III P 1 Y257 K649 Y662 V663 Y236 K628 Y641 V642 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 A 4.00 BS02 AGS A 1 P185 V186 I187 P214 G215 I216 G217 K218 T219 A220 I351 L393 P164 V165 I166 P193 G194 I195 G196 K197 T198 A199 I330 L372 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 A 4.00 BS03 AGS A 2 V580 V581 S616 G617 S618 G619 T621 E622 I783 R787 Y819 M823 G824 A825 V559 V560 S595 G596 S597 G598 T600 E601 I762 R766 Y798 M802 G803 A804 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 A 4.00 BS04 AGS B 1 R333 R334 R312 R313 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 B 4.00 BS01 III P 1 Y257 K258 G661 V663 Y236 K237 G640 V642 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 B 4.00 BS02 AGS B 1 P185 V186 I187 R189 P214 G215 G217 K218 T219 A220 I351 L355 P389 D390 L393 P164 V165 I166 R168 P193 G194 G196 K197 T198 A199 I330 L334 P368 D369 L372 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 B 4.00 BS03 AGS B 2 V580 V581 S616 G617 S618 G619 K620 T621 E622 D686 L775 I783 A825 R826 N829 V559 V560 S595 G596 S597 G598 K599 T600 E601 D665 L754 I762 A804 R805 N808 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 C 4.00 BS01 III P 1 Y257 K258 G661 Y662 V663 Y665 Y236 K237 G512 Y513 V514 Y516 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 C 4.00 BS02 AGS C 1 P185 V186 I187 R189 P214 G215 I216 G217 K218 T219 A220 I351 L355 P389 L393 P164 V165 I166 R168 P193 G194 I195 G196 K197 T198 A199 I330 L334 P368 L372 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 C 4.00 BS03 AGS C 2 E579 V580 V581 S616 G617 S618 G619 K620 T621 E622 L775 I783 A825 N829 E430 V431 V432 S467 G468 S469 G470 K471 T472 E473 L626 I634 A676 N680 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 C 4.00 BS04 AGS D 1 I204 R334 I183 R313 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 D 4.00 BS01 III P 1 K256 Y257 K258 K649 Y662 V663 K235 Y236 K237 K500 Y513 V514 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 D 4.00 BS02 AGS D 1 D184 P185 V186 I187 R189 P214 G215 I216 G217 K218 T219 A220 I351 P389 D390 L393 D163 P164 V165 I166 R168 P193 G194 I195 G196 K197 T198 A199 I330 P368 D369 L372 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 D 4.00 BS03 AGS D 2 V580 V581 Q583 S616 G617 S618 G619 K620 T621 E622 E687 T726 L775 I783 R787 A825 N829 V431 V432 Q434 S467 G468 S469 G470 K471 T472 E473 E538 T577 L626 I634 R638 A676 N680 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 E 4.00 BS01 III P 1 K256 Y257 K258 K649 V663 K235 Y236 K237 K628 V642 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 E 4.00 BS02 AGS E 1 P185 V186 I187 G215 I216 G217 K218 T219 A220 I351 L355 D390 L393 P164 V165 I166 G194 I195 G196 K197 T198 A199 I330 L334 D369 L372 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 E 4.00 BS03 AGS E 2 E579 V580 V581 S616 G617 S618 G619 K620 T621 E622 D686 N728 I783 R787 A825 R826 E558 V559 V560 S595 G596 S597 G598 K599 T600 E601 D665 N707 I762 R766 A804 R805 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 F 4.00 BS01 AGS A 1 G329 E332 R333 G308 E311 R312 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 F 4.00 BS02 AGS F 1 V186 I187 R189 G215 I216 G217 K218 T219 A220 I351 D390 V165 I166 R168 G194 I195 G196 K197 T198 A199 I330 D369 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5vy9 F 4.00 BS03 AGS F 2 E579 V580 V581 S616 G617 S618 G619 K620 T621 E622 L775 I783 R787 A825 R826 E558 V559 V560 S595 G596 S597 G598 K599 T600 E601 L754 I762 R766 A804 R805 P31539 28619716 QFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLEECLEVLPNHE 5w3f A 3.70 BS02 GTP A 1 G10 Q11 A12 Q15 A101 N103 S141 G144 G145 T146 N207 F225 L228 N229 I232 G10 Q11 A12 Q15 A101 N103 S141 G144 G145 T146 N207 F225 L228 N229 I232 P09733 28652389 MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADS 5w3f B 3.70 BS01 GDP B 1 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 D177 N204 N226 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 D177 N204 N226 P02557 28652389 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQE 5w3h A 4.00 BS01 GTP A 1 G10 Q11 A12 Q15 E72 A101 S141 G144 T146 T180 E184 N207 F225 N229 G10 Q11 A12 Q15 E72 A101 S141 G144 T146 T180 E184 N207 F225 N229 P09733 28652389 MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADS 5w3h B 4.00 BS01 GTP A 1 L246 K252 L246 K252 P02557 28652389 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQE 5w3h B 4.00 BS02 GDP B 1 Q11 C12 Q15 N99 S138 G141 T143 G144 D177 E181 N204 Y222 N226 Q11 C12 Q15 N99 S138 G141 T143 G144 D177 E181 N204 Y222 N226 P02557 28652389 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQE 5w3h B 4.00 BS03 EP B 1 C211 L215 L217 D224 L228 P272 L273 T274 A275 I276 Q279 R282 C211 L215 L217 D224 L228 P272 L273 T274 A275 I276 Q279 R282 P02557 28652389 MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQE 5w3j A 4.00 BS01 GTP A 1 G10 Q11 A12 Q15 A101 S141 G143 G144 T146 T180 N207 F225 L228 G10 Q11 A12 Q15 A101 S141 G143 G144 T146 T180 N207 F225 L228 P09733 28652389 MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADS 5w3j A 4.00 BS02 MG A 1 Q11 D70 E72 Q11 D70 E72 P09733 28652389 MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADS 5w3j B 4.00 BS01 GDP B 1 Q11 C12 G98 N99 G141 G142 T143 G144 D177 N204 L207 N226 Q11 C12 G98 N99 G141 G142 T143 G144 D177 N204 L207 N226 P02557 28652389 MREIIHISTGQCGNQIGAKFWEVICDEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNHLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGFAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQE 5w3j B 4.00 BS02 TA1 B 1 V23 D26 E27 H227 Q359 G360 L361 V23 D26 E27 H227 Q359 G360 L361 P02557 28652389 MREIIHISTGQCGNQIGAKFWEVICDEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNHLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGFAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQE 5w5h A 2.79 BS01 NUC B 1 R38 Q42 L46 T48 Y50 W147 L150 K151 G153 G154 Y157 E176 I183 Y186 R187 G190 F191 L193 A194 N216 Y218 Y252 R255 Y256 K259 R262 L286 H289 Q290 L293 K336 F339 V341 L344 D345 V372 D379 R30 Q34 L38 T40 Y42 W133 L136 K137 G139 G140 Y143 E162 I169 Y172 R173 G176 F177 L179 A180 N202 Y204 Y238 R241 Y242 K245 R248 L272 H275 Q276 L279 K318 F321 V323 L326 D327 V354 D361 P09914 QVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQENVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEAPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAAD 5w7g A 4.50 BS01 NUC q 1 R15 Y16 W23 R24 S41 A44 D45 Q48 Y49 I75 A79 E82 H86 R10 Y11 W18 R19 S36 A39 D40 Q43 Y44 I70 A74 E77 H81 Q70LC6 28639939 RKLRQDSTDRYKTKLYLWRNLGGLIPEDMAISVTESITADWKQYNDMMSKVRNETLDILKTNKVATEDYIGYIAFAEELAHQVWKNKNSSPDPNTANEASKTDLESKYSDVYGLDVTVLDAIYNAVIPIIM 5w7g A 4.50 BS02 NUC r 1 L8 R9 S12 R15 Y16 K19 Y49 M53 R57 T71 I75 K90 N93 M136 L3 R4 S7 R10 Y11 K14 Y44 M48 R52 T66 I70 K85 N88 M131 Q70LC6 28639939 RKLRQDSTDRYKTKLYLWRNLGGLIPEDMAISVTESITADWKQYNDMMSKVRNETLDILKTNKVATEDYIGYIAFAEELAHQVWKNKNSSPDPNTANEASKTDLESKYSDVYGLDVTVLDAIYNAVIPIIM 5w7g B 4.50 BS01 NUC q 1 Q8 K11 D12 Q15 Y16 Y19 F48 H52 R55 K59 W72 K88 A91 Q2 K5 D6 Q9 Y10 Y13 F42 H46 R49 K53 W66 K82 A85 Q70LC7 28639939 RQDSKDRYQYKQYIYRSIGGIVPPEMAETVTANQTAQWEAGFTPYHKLRLAIKEICKTDGIPNIKWGMYIAFGEKLLKSYLKMKAGSASSDMIAEYINNAISAFSSRTGISQETAQKIADFITSNY 5w7g B 4.50 BS02 NUC r 1 Y16 Q40 Q43 W44 G47 Y51 A77 E80 K81 Y10 Q34 Q37 W38 G41 Y45 A71 E74 K75 Q70LC7 28639939 RQDSKDRYQYKQYIYRSIGGIVPPEMAETVTANQTAQWEAGFTPYHKLRLAIKEICKTDGIPNIKWGMYIAFGEKLLKSYLKMKAGSASSDMIAEYINNAISAFSSRTGISQETAQKIADFITSNY 5w7g D 4.50 BS01 NUC q 1 Q8 K11 D12 Q15 Y19 F48 H52 R55 K59 N69 W72 K88 A91 Q2 K5 D6 Q9 Y13 F42 H46 R49 K53 N63 W66 K82 A85 Q70LC7 28639939 RQDSKDRYQYKQYIYRSIGGIVPPEMAETVTANQTAQWEAGFTPYHKLRLAIKEICKTDGIPNIKWGMYIAFGEKLLKSYLKMKAGSASSDMIAEYINNAISAFSSRTGISQETAQKIADFITSNY 5w7g D 4.50 BS02 NUC r 1 K11 Q15 Y16 Q40 Q43 W44 G47 Y51 A77 E80 K81 K5 Q9 Y10 Q34 Q37 W38 G41 Y45 A71 E74 K75 Q70LC7 28639939 RQDSKDRYQYKQYIYRSIGGIVPPEMAETVTANQTAQWEAGFTPYHKLRLAIKEICKTDGIPNIKWGMYIAFGEKLLKSYLKMKAGSASSDMIAEYINNAISAFSSRTGISQETAQKIADFITSNY 5w7g o 4.50 BS02 NUC r 1 L8 R9 S12 R15 Y16 K19 Y49 M53 R57 K90 N93 M136 L3 R4 S7 R10 Y11 K14 Y44 M48 R52 K85 N88 M131 Q70LC6 28639939 RKLRQDSTDRYKTKLYLWRNLGGLIPEDMAISVTESITADWKQYNDMMSKVRNETLDILKTNKVATEDYIGYIAFAEELAHQVWKNKNSSPDPNTANEASKTDLESKYSDVYGLDVTVLDAIYNAVIPIIM 5w80 A 2.00 BS01 9XJ A 1 L57 V65 A78 K80 M112 L126 E129 V130 Y131 E135 E178 L181 I194 D195 L198 L14 V22 A35 K37 M69 L83 E86 V87 Y88 E92 E135 L138 I151 D152 L155 Q9BJF5 TAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 5w80 A 2.00 BS02 CA A 1 D451 S455 K457 D397 S401 K403 Q9BJF5 TAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 5w81 A 3.37 BS01 ATP A 1 W402 M459 G460 G462 K463 S464 S465 Q492 Y1345 N1349 W402 M428 G429 G431 K432 S433 S434 Q461 Y1060 N1064 3.6.3.49 Q1LX78 MQRSPVEDANCLSRYFFWWTNPIMRKGFKEKLRPSDVYQAPSQDAADILAERLEKEWDREVASGKKKPSLLRAMARCYIKPFLLFGFLLYIGEATKTVQPQLLGRIIASFDPAHEPERANGYFLAFGLGLLFTARFLLLQPAMFGLHHLGMQIRIALFSIIYKKTLKLSSRVLDKISTGQLVSLMSANLGKFDQSLGMAHFIWISPLQCILCTGLIWELIDVNSFCALAAISLLGVLQAFLSHKMGPYKAQKVLLTNKRLALTSEIMENLHSVKAYGWEEIMETLIKNIRQDEVKLTRKIGSLRYFYSSAYFFSAIFVIVAAVVPHALSRGINLRRIFTTLSYCMVLRMTVTRQLPGSIQMWYDTMRLIWKIEEFLSKEEYKLMEYDLSITELELQDVTASWDEGAPVLKDISLKLKKGEMLAVTGSMGSGKSSLLMTILGELVPSSGKIRHSGRISYSSQTAWIMPGTIRDNILFGLTYDEYRYKSVVKACQLEEDLAALPEKDKTPMAEGGLNLSGGQKARVALARAVYRDADLYLLDAPFTHLDIATEKEIFDKCLCKLMASKTRILVTNKIEHLKRADKILLLHNGESFFYGTFPELQSERPDFSSWNTYVRYVSNNKSLLYVLIFILFIAAIEIAGSVAGIFLITDELTSSYYILYIYVATSESLLAMGFFRGLPFVHTTITISKKLHQKMLHAVLSAPMSVLNTMKTGRIMNRFTKDMATIDDMLPLLMFDFVQLTVVVVGCILVVSIVRPYIFLAATPLAIIFIVMRKYFLRTGQQLKQLETEARSPIFSHLIMSLKGLWTIRAFERQAYFEALFHKTLNTHTATWFLYLSTLRWFLFRADILFVFFFTLAAWIAVGTNQDKPGEIGIIICLAMLILGTFQWCVATSIAVDGMMRSVDRVFKFIDLPSETSSWPHRGQIEVRNLTVKYTEAGHAVLKNLSFSAEGRQRVGILGRTGSGKSSLFNALLKLVYTDGEISIDGVNWNKMPLQKWRKAFGVVPQKVFIFTGPLRMNLDPYGCHSDEELWRVAEEVGLKTVIEQFPDKLDFQLEYGGYVLSNGHKQLICLARSILSGARILLLDQPSAHLDPVTIKVLKKTLRQSFSTCTILLSEHKVEPLLECQSFLMMDKGQVKTYDSIQKLLNETSHLKQAISPAERLKLFPRRNSSM 5w81 A 3.37 BS02 ATP A 2 L545 N546 S548 G550 Q551 Y1220 T1247 G1248 G1250 K1251 S1252 S1253 Q1292 L514 N515 S517 G519 Q520 Y935 T962 G963 G965 K966 S967 S968 Q1007 3.6.3.49 Q1LX78 MQRSPVEDANCLSRYFFWWTNPIMRKGFKEKLRPSDVYQAPSQDAADILAERLEKEWDREVASGKKKPSLLRAMARCYIKPFLLFGFLLYIGEATKTVQPQLLGRIIASFDPAHEPERANGYFLAFGLGLLFTARFLLLQPAMFGLHHLGMQIRIALFSIIYKKTLKLSSRVLDKISTGQLVSLMSANLGKFDQSLGMAHFIWISPLQCILCTGLIWELIDVNSFCALAAISLLGVLQAFLSHKMGPYKAQKVLLTNKRLALTSEIMENLHSVKAYGWEEIMETLIKNIRQDEVKLTRKIGSLRYFYSSAYFFSAIFVIVAAVVPHALSRGINLRRIFTTLSYCMVLRMTVTRQLPGSIQMWYDTMRLIWKIEEFLSKEEYKLMEYDLSITELELQDVTASWDEGAPVLKDISLKLKKGEMLAVTGSMGSGKSSLLMTILGELVPSSGKIRHSGRISYSSQTAWIMPGTIRDNILFGLTYDEYRYKSVVKACQLEEDLAALPEKDKTPMAEGGLNLSGGQKARVALARAVYRDADLYLLDAPFTHLDIATEKEIFDKCLCKLMASKTRILVTNKIEHLKRADKILLLHNGESFFYGTFPELQSERPDFSSWNTYVRYVSNNKSLLYVLIFILFIAAIEIAGSVAGIFLITDELTSSYYILYIYVATSESLLAMGFFRGLPFVHTTITISKKLHQKMLHAVLSAPMSVLNTMKTGRIMNRFTKDMATIDDMLPLLMFDFVQLTVVVVGCILVVSIVRPYIFLAATPLAIIFIVMRKYFLRTGQQLKQLETEARSPIFSHLIMSLKGLWTIRAFERQAYFEALFHKTLNTHTATWFLYLSTLRWFLFRADILFVFFFTLAAWIAVGTNQDKPGEIGIIICLAMLILGTFQWCVATSIAVDGMMRSVDRVFKFIDLPSETSSWPHRGQIEVRNLTVKYTEAGHAVLKNLSFSAEGRQRVGILGRTGSGKSSLFNALLKLVYTDGEISIDGVNWNKMPLQKWRKAFGVVPQKVFIFTGPLRMNLDPYGCHSDEELWRVAEEVGLKTVIEQFPDKLDFQLEYGGYVLSNGHKQLICLARSILSGARILLLDQPSAHLDPVTIKVLKKTLRQSFSTCTILLSEHKVEPLLECQSFLMMDKGQVKTYDSIQKLLNETSHLKQAISPAERLKLFPRRNSSM 5w81 A 3.37 BS03 MG A 1 S464 Q492 S433 Q461 3.6.3.49 Q1LX78 MQRSPVEDANCLSRYFFWWTNPIMRKGFKEKLRPSDVYQAPSQDAADILAERLEKEWDREVASGKKKPSLLRAMARCYIKPFLLFGFLLYIGEATKTVQPQLLGRIIASFDPAHEPERANGYFLAFGLGLLFTARFLLLQPAMFGLHHLGMQIRIALFSIIYKKTLKLSSRVLDKISTGQLVSLMSANLGKFDQSLGMAHFIWISPLQCILCTGLIWELIDVNSFCALAAISLLGVLQAFLSHKMGPYKAQKVLLTNKRLALTSEIMENLHSVKAYGWEEIMETLIKNIRQDEVKLTRKIGSLRYFYSSAYFFSAIFVIVAAVVPHALSRGINLRRIFTTLSYCMVLRMTVTRQLPGSIQMWYDTMRLIWKIEEFLSKEEYKLMEYDLSITELELQDVTASWDEGAPVLKDISLKLKKGEMLAVTGSMGSGKSSLLMTILGELVPSSGKIRHSGRISYSSQTAWIMPGTIRDNILFGLTYDEYRYKSVVKACQLEEDLAALPEKDKTPMAEGGLNLSGGQKARVALARAVYRDADLYLLDAPFTHLDIATEKEIFDKCLCKLMASKTRILVTNKIEHLKRADKILLLHNGESFFYGTFPELQSERPDFSSWNTYVRYVSNNKSLLYVLIFILFIAAIEIAGSVAGIFLITDELTSSYYILYIYVATSESLLAMGFFRGLPFVHTTITISKKLHQKMLHAVLSAPMSVLNTMKTGRIMNRFTKDMATIDDMLPLLMFDFVQLTVVVVGCILVVSIVRPYIFLAATPLAIIFIVMRKYFLRTGQQLKQLETEARSPIFSHLIMSLKGLWTIRAFERQAYFEALFHKTLNTHTATWFLYLSTLRWFLFRADILFVFFFTLAAWIAVGTNQDKPGEIGIIICLAMLILGTFQWCVATSIAVDGMMRSVDRVFKFIDLPSETSSWPHRGQIEVRNLTVKYTEAGHAVLKNLSFSAEGRQRVGILGRTGSGKSSLFNALLKLVYTDGEISIDGVNWNKMPLQKWRKAFGVVPQKVFIFTGPLRMNLDPYGCHSDEELWRVAEEVGLKTVIEQFPDKLDFQLEYGGYVLSNGHKQLICLARSILSGARILLLDQPSAHLDPVTIKVLKKTLRQSFSTCTILLSEHKVEPLLECQSFLMMDKGQVKTYDSIQKLLNETSHLKQAISPAERLKLFPRRNSSM 5wan A 1.80 BS01 URA A 1 F7 W15 M49 F10 W18 M52 1.14.99.46 A0A1R1KFF4 20369853 ERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTDPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLP 5wan A 1.80 BS02 FMN A 1 F7 M49 I50 T87 V118 G120 R141 Y142 A188 G189 Q190 S191 G194 F206 F208 L329 F10 M52 I53 T90 V121 G123 R144 Y145 A191 G192 Q193 S194 G197 F209 F211 L313 1.14.99.46 A0A1R1KFF4 20369853 ERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTDPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLP 5wbv A 2.30 BS03 9ZY A 1 G229 S251 V252 M253 W264 A268 A269 F281 A289 Y307 F311 G129 S151 V152 M153 W164 A168 A169 F181 A189 Y207 F211 2.1.1.43 Q4FZB7 MSAKELCENDDLATSLVLDPYLGFQTHKMNKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFK 5wcj A 1.70 BS01 SAH A 1 V500 G501 G503 E524 I525 M529 D551 G552 D575 V576 D577 F592 V31 G32 G34 E55 I56 M60 D82 G83 D106 V107 D108 F122 2.1.1.- Q8N6R0 CCEHHKAMIAGLALLRNPELLLEIPLALLVVGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQSDRMKVHIADGLDYIASLAGGGEARPCYDVIMFDVDSDPTLGMSCPPPAFVEQSFLQKVKSILTPEGVFILNLVCRDLGLKDSVLAGLKAVFPLLYVRRIEGEVNEILFCQLHPEQKLATPELLETAQALERTLRKPRGWDDTYVLSDML 5wcl A BS01 9XG A 1 F27 I36 L41 M60 E63 V72 F77 M80 R83 T142 F27 I36 L41 M60 E63 V72 F77 M80 R83 T97 P19429 27825981 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKFKRPTLRRVRISADAMMQALLGARAKGH 5wdr A 1.60 BS01 MG A 1 S17 T35 S17 T35 3.6.5.2 F2UBE5 28686159 MTEYRLVVVGTGGVGKSALTIQLIQQHFVTEYDPTIEDSYRKHVSIDDEACLLDILDTAGQEDYSAMRDQYMRTGEGFLCVYSIDSQQSLDEIHSFREQILRVKDQDEVPMILVGNKCDLEEHREVSTEAGQAVAKSYSIPFMETSAKKRINVEEAFYQLVREIRKY 5wdr A 1.60 BS02 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 V29 T30 E31 Y32 P34 T35 G60 N116 K117 D119 L120 S146 A147 K148 G12 G13 V14 G15 K16 S17 A18 F28 V29 T30 E31 Y32 P34 T35 G60 N116 K117 D119 L120 S146 A147 K148 3.6.5.2 F2UBE5 28686159 MTEYRLVVVGTGGVGKSALTIQLIQQHFVTEYDPTIEDSYRKHVSIDDEACLLDILDTAGQEDYSAMRDQYMRTGEGFLCVYSIDSQQSLDEIHSFREQILRVKDQDEVPMILVGNKCDLEEHREVSTEAGQAVAKSYSIPFMETSAKKRINVEEAFYQLVREIRKY 5wds A 1.85 BS01 GDP A 1 G13 G15 K16 S17 A18 F28 V29 T30 N116 K117 D119 L120 S146 A147 K148 G15 G17 K18 S19 A20 F30 V31 T32 N118 K119 D121 L122 S148 A149 K150 3.6.5.2 F2UBE5 28686159 MAMTEYRLVVVGTGGVGKSALTIQLIQQHFVTEYDPTIEDSYRKHVSIDDEACLLDILDTAGQEDYSAMRDQYMRTGEGFLCVYSIDSQQSLDEIHSFREQILRVKDQDEVPMILVGNKCDLEEHREVSTEAGQAVAKSYSIPFMETSAKKRINVEEAFYQLVREIRKY 5wds B 1.85 BS01 GDP B 1 G13 V14 G15 K16 S17 A18 F28 V29 T30 N116 K117 D119 L120 S146 A147 K148 G14 V15 G16 K17 S18 A19 F29 V30 T31 N117 K118 D120 L121 S147 A148 K149 3.6.5.2 F2UBE5 28686159 AMTEYRLVVVGTGGVGKSALTIQLIQQHFVTEYDPTIEDSYRKHVSIDDEACLLDILDTAGQEDYSAMRDQYMRTGEGFLCVYSIDSQQSLDEIHSFREQILRVKDQDEVPMILVGNKCDLEEHREVSTEAGQAVAKSYSIPFMETSAKKRINVEEAFYQLVREIRKY 5wtb D 3.30 BS01 III H 1 H299 D300 G301 P332 S333 D334 L335 T336 N339 D340 Y387 Q419 M422 H424 F433 L436 L557 Y574 N575 Y576 G578 Y579 S580 N581 F582 I583 V584 T585 S586 N587 D588 H24 D25 G26 P57 S58 D59 L60 T61 N64 D65 Y112 Q144 M147 H149 F158 L161 L272 Y289 N290 Y291 G293 Y294 S295 N296 F297 I298 V299 T300 S301 N302 D303 Q932F7 28258151 NNVNDLITVTKQTIKVGDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTINYDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKYEDIKARLTLYSYIDKQAVPNETSLNLTFATAGKETSQNVSVDYQDPMVHGDSNIQSIFTKLDENKQTIEQQIYVNPLKKTATNTKVDIAGSGNGSTIIDQNTEMKVYKVNPNQQLPQSNRIYDFSQYEDVTSQFDNKKSFSNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDKYGYYNYAGYSNFIVTSNDTGGGDGTVKP 5wtb B 3.30 BS01 III F 1 H299 D300 G301 P332 S333 D334 L335 T336 N339 D340 Y387 Q419 S431 I432 F433 L436 L557 Y579 S580 N581 F582 I583 V584 T585 S586 N587 D588 H24 D25 G26 P57 S58 D59 L60 T61 N64 D65 Y112 Q144 S156 I157 F158 L161 L282 Y300 S301 N302 F303 I304 V305 T306 S307 N308 D309 Q932F7 28258151 NNVNDLITVTKQTIKVGDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTINYDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKYEDIKARLTLYSYIDKQAVPNETSLNLTFATAGKETSQNVSVDYQDPMVHGDSNIQSIFTKLDENKQTIEQQIYVNPLKKTATNTKVDIAGSQVDDYGNIKLGNGSTIIDQNTEMKVYKVNPNQQLPQSNRIYDFSQYEDVTSQFDNKKSFSNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDYNYAGYSNFIVTSNDTGGGDGTVKP 5xh8 A 2.10 BS01 GOL A 1 D64 L82 F121 D122 D194 D41 L59 F98 D99 D171 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xh8 A 2.10 BS02 GOL A 2 F121 I146 H147 R193 F98 I123 H124 R170 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xh8 A 2.10 BS03 GOL A 3 G113 I114 N115 D175 G90 I91 N92 D152 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xh8 A 2.10 BS04 GOL A 4 W148 H223 E224 T253 W125 H200 E201 T230 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xh8 A 2.10 BS05 GOL A 5 Y30 T48 K477 S590 W591 Y7 T25 K454 S567 W568 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xha A 2.10 BS01 FRU A 1 I146 H147 R193 E271 E296 I123 H124 R170 E248 E273 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xha A 2.10 BS02 FRU A 2 D64 L82 F121 D122 R193 D194 E271 Y342 D41 L59 F98 D99 R170 D171 E248 Y319 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xha A 2.10 BS03 FRU A 3 W148 T190 L222 H223 E224 T253 F268 W125 T167 L199 H200 E201 T230 F245 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xha A 2.10 BS04 FRU A 4 I441 K446 Y577 A578 N579 G580 I418 K423 Y554 A555 N556 G557 G7XM46 MSVVIDYNVAPPNLSTLPNGSLFETWRPRAHVLPPNGQIGDPCLHYTDPATGLFHVGFLHDGSGISSATTDDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYTRGSETQSLAVSSDGGSNFTKLDQGPVIPGPPFAYNVTAFRDPYVFQNPTLDSLLHSKNNTWYTVISGGLHEKGPAQFLYRQYDSDFQYWEYLGQWWHEPTNSTWGNGTWAGRWAFNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSFNPNMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAEGFPTNQQNWTGTLLLPRELRVLYIPNVVDNALARESGASWQVVSSDGSAGTVELQTLGISIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSGFQILSSEHESTTVYYQFSNESIIVDRSNTSAAARTTDGIDSSAEAGKLRLFDVLNGGEQAIETLDLTLVVDNSVLEVYANGRFALSTWVRSWYANSTNISFFHNGVGGVAFSKVTVSEGLYDAWPDRQY 5xnx A 3.70 BS01 MG A 1 H56 D81 D145 H34 D59 D103 2.7.6.5,3.1.7.2 P9WHG9 28672070 LEPLVAVHREIYPKADLSILQRAYEVADQRYITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKDDMAWMRQLLDWQREAA 5xun A 2.00 BS01 ACO A 1 C23 E25 L28 L94 G95 R96 L97 A98 I99 Q104 G105 Q106 G107 W108 G109 E110 V134 E135 L137 K140 A141 A143 F144 F145 R147 C21 E23 L26 L92 G93 R94 L95 A96 I97 Q102 G103 Q104 G105 W106 G107 E108 V132 E133 L135 K138 A139 A141 F142 F143 R145 A0A081LU80 QQLTIEMIADAFSYDITGFDCGEEALNTFLKEHLKRQHDGQILRGYALVSGDTVPRLLGYYTLSGSCFERGMLPSKTQQKKIPYQNAPSVTLGRLAIDKSVQGQGWGEMLVAHVMRVVWGASKAVGIYGLFVEALNEKAKAFFLRLGFIQLVDENSNLLFYPTKSIEQLF 5xun B 2.00 BS01 ACO B 1 C23 L28 G95 L97 A98 I99 Q104 G105 Q106 G107 G109 E110 V134 E135 A136 L137 A141 R147 C21 L26 G93 L95 A96 I97 Q102 G103 Q104 G105 G107 E108 V132 E133 A134 L135 A139 R145 A0A081LU80 QQLTIEMIADAFSYDITGFDCGEEALNTFLKEHLKRQHDGQILRGYALVSGDTVPRLLGYYTLSGSCFERGMLPSKTQQKKIPYQNAPSVTLGRLAIDKSVQGQGWGEMLVAHVMRVVWGASKAVGIYGLFVEALNEKAKAFFLRLGFIQLVDENSNLLFYPTKSIEQLFT