2n8l A BS01 NUC B 1 V34 G35 A36 I38 G39 K40 K41 G42 K46 K57 I58 R69 V34 G35 A36 I38 G39 K40 K41 G42 K46 K57 I58 R69 O42254 GAMGPSSVSGAAPFSSFMPPEQETVHVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVVITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGDDGKTVNELQNLTAAEVVVPRDQTPDENEQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSGQLQA 2n8m A BS01 NUC B 1 G117 R118 I120 K122 G123 G124 V127 V139 V140 P141 R142 D143 Q180 G117 R118 I120 K122 G123 G124 V127 V139 V140 P141 R142 D143 Q180 O42254 GAMGPSSVSGAAPFSSFMPPEQETVHVFIPAQAVGAIIGDDGQHIKQLSRFASASIKIAPPETPDSKVRMVVITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENEQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSGQLQA 5aan A 1.60 BS01 CA A 1 D73 N75 D77 A79 E84 D71 N73 D75 A77 E82 Q9VWX8 KKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5aan A 1.60 BS02 CA A 2 D156 N158 D160 R162 E167 D154 N156 D158 R160 E165 Q9VWX8 KKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5aan A 1.60 BS03 CA A 3 D109 D111 D113 Y115 E120 D107 D109 D111 Y113 E118 Q9VWX8 KKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5aan A 1.60 BS04 XOC A 1 W30 Y52 F85 L89 T92 W103 L182 W28 Y50 F83 L87 T90 W101 L180 Q9VWX8 KKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5b6d A 1.65 BS01 C5P A 1 R31 Y104 C155 R175 A176 N177 D178 D186 H216 Y218 R27 Y100 C151 R171 A172 N173 D174 D182 H212 Y214 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6d A 1.65 BS02 C5P B 1 K133 R134 K129 R130 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6d B 1.65 BS01 C5P A 1 K133 R134 K129 R130 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6d B 1.65 BS02 C5P B 1 R31 Y104 C155 R175 A176 N177 D178 D186 H216 Y218 R27 Y100 C151 R171 A172 N173 D174 D182 H212 Y214 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6e A 1.80 BS01 5HM A 1 R31 T102 Y104 C155 R175 A176 N177 D178 D186 H216 Y218 R27 T98 Y100 C151 R171 A172 N173 D174 D182 H212 Y214 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAARPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6e A 1.80 BS02 5HM B 1 K133 R134 K129 R130 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAARPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6e B 1.80 BS01 5HM A 1 K133 R134 K129 R130 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAAPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b6e B 1.80 BS02 5HM B 1 R31 T102 Y104 C155 R175 A176 N177 D178 D186 H216 Y218 R27 T98 Y100 C151 R171 A172 N173 D174 D182 H212 Y214 B4Y380 28000775 TFGTFQDAYLSQLRDIYHSPEFRNAPRGQASRERIGAGFRLLDPVQRHISVPARRANVVFNFAEALWYLSGSDRLDFIQYYAPGIAAYSADGRTLRGTAYGPRIFRHPAGGVNQWENVVKTLTDDPDSKRAVIQIFDPRELAVADNIDVACTLALQFLIRDGLLCGIGYMRANDAFRGAVSDVFSFTFLQEFTARYLGLGIGTYHHVVGSVHIYDSDARWAERVLDAAPGFPAMPDGDNWPHVRRVLEWEERLRTNAARLSADALDALDLPAYWKHVVALFEAHRQVRHEDTPDRALLAALPEVYRQSLAVKWPGHFG 5b7g A 1.40 BS01 ADE A 1 T104 A105 G106 E198 W199 E218 E219 M220 S243 N244 T78 A79 G80 E172 W173 E192 E193 M194 S217 N218 3.2.2.16,3.2.2.9 A0KGU9 ASAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF 5b7g B 1.40 BS01 ADE B 1 T104 A105 G106 E198 W199 E218 M220 S243 N244 T77 A78 G79 E171 W172 E191 M193 S216 N217 3.2.2.16,3.2.2.9 A0KGU9 SAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF 5cpr B 2.22 BS01 ZN B 1 C275 C319 C321 C324 C173 C217 C219 C222 2.1.1.43 Q4FZB7 MSAKELCENDDLATSLVLDPYLGFQTHKMNRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKS 5cpr B 2.22 BS02 SAM B 1 H98 Y203 S205 E206 G209 A210 F250 A269 F270 I271 N272 H273 Y307 F312 C319 E320 C321 H27 Y101 S103 E104 G107 A108 F148 A167 F168 I169 N170 H171 Y205 F210 C217 E218 C219 2.1.1.43 Q4FZB7 MSAKELCENDDLATSLVLDPYLGFQTHKMNRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKS 5cpr B 2.22 BS03 539 B 1 G229 S251 V252 M253 W264 A268 A269 F281 S283 A289 Y307 G127 S149 V150 M151 W162 A166 A167 F179 S181 A187 Y205 2.1.1.43 Q4FZB7 MSAKELCENDDLATSLVLDPYLGFQTHKMNRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKS 5e7y A 2.00 BS01 HEM A 1 K69 L86 A87 W96 A264 G265 T268 T269 T327 A328 F331 P392 F393 G394 R398 A399 C400 I401 G402 F405 A406 K65 L82 A83 W92 A260 G261 T264 T265 T323 A324 F327 P388 F389 G390 R394 A395 C396 I397 G398 F401 A402 1.14.14.1,1.6.2.4 P14779 MPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLGKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELSVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 5e7y B 2.00 BS01 HEM B 1 K69 L86 A87 W96 F107 A264 G265 T268 T269 L272 T327 A328 F331 P392 F393 G394 R398 A399 C400 I401 G402 F405 A406 K66 L83 A84 W93 F104 A261 G262 T265 T266 L269 T324 A325 F328 P389 F390 G391 R395 A396 C397 I398 G399 F402 A403 1.14.14.1,1.6.2.4 P14779 EMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLGKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELSVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 5ed3 B 1.31 BS01 AMP B 1 F19 F41 H42 D43 I44 S45 L53 N99 G105 Q106 S107 V108 H112 H114 F8 F30 H31 D32 I33 S34 L42 N88 G94 Q95 S96 V97 H101 H103 3.-.-.- P49773 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG 5ed6 B 1.52 BS01 AMP B 1 I18 F19 F41 H42 D43 I44 S45 L53 N99 G105 Q106 S107 V108 H112 I7 F8 F30 H31 D32 I33 S34 L42 N88 G94 Q95 S96 V97 H101 3.-.-.- P49773 RPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLAVLGGRQMHWPPG 5ffg A 2.25 BS01 CA A 1 D284 I285 N286 D288 Y290 D292 D281 I282 N283 D285 Y287 D289 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHIL 5ffg A 2.25 BS02 CA A 2 D349 D351 D353 F355 D357 N377 D346 D348 D350 F352 D354 N374 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHIL 5ffg A 2.25 BS03 CA A 3 D414 D416 N418 Y420 D422 D411 D413 N415 Y417 D419 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHIL 5ffg A 2.25 BS04 CA A 4 D230 N232 D234 I236 D238 D257 D227 N229 D231 I233 D235 D254 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHIL 5ffg B 2.25 BS01 CA B 1 S127 M128 D130 D131 K338 S15 M16 D18 D19 K226 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVEL 5ffg B 2.25 BS02 CA B 2 D123 S125 S127 E223 D254 A255 D11 S13 S15 E111 D142 A143 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVEL 5ffo A 3.49 BS01 CA A 1 D284 I285 N286 D288 Y290 D292 D281 I282 N283 D285 Y287 D289 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLD 5ffo A 3.49 BS02 CA A 2 D349 D351 D353 F355 D357 N377 D346 D348 D350 F352 D354 N374 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLD 5ffo A 3.49 BS03 CA A 3 D414 D416 N418 Y420 D422 D411 D413 N415 Y417 D419 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLD 5ffo A 3.49 BS04 CA A 4 D230 N232 D234 I236 D238 D227 N229 D231 I233 D235 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLD 5ffo B 3.49 BS01 MN B 1 S127 D130 D131 D254 S15 D18 D19 D142 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL 5ffo B 3.49 BS02 MN B 2 D123 S125 A126 S127 T221 E223 D254 D11 S13 A14 S15 T109 E111 D142 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL 5ffo B 3.49 BS03 MN B 3 E162 N218 D220 T221 P222 E223 E50 N106 D108 T109 P110 E111 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL 5ffo E 3.49 BS01 CA E 1 D284 I285 N286 D288 Y290 D292 D284 I285 N286 D288 Y290 D292 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQA 5ffo E 3.49 BS02 CA E 2 D349 D351 D353 F355 D357 N377 D349 D351 D353 F355 D357 N377 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQA 5ffo E 3.49 BS03 CA E 3 D414 D416 N418 Y420 D422 D414 D416 N418 Y420 D422 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQA 5ffo E 3.49 BS04 CA E 4 D230 N232 D234 I236 D238 D257 D230 N232 D234 I236 D238 D257 P06756 FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQA 5ffo F 3.49 BS01 MN F 1 S127 D130 D131 D254 S15 D18 D19 D142 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL 5ffo F 3.49 BS02 MN F 2 D123 S125 S127 T221 E223 D11 S13 S15 T109 E111 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL 5ffo F 3.49 BS03 MN F 3 E162 N218 D220 P222 E223 E50 N106 D108 P110 E111 P18564 DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL 5fyx A 1.80 BS01 CA A 1 D73 N75 D77 A79 E84 D67 N69 D71 A73 E78 Q9VWX8 KLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5fyx A 1.80 BS02 CA A 2 D156 N158 D160 R162 E167 D140 N142 D144 R146 E151 Q9VWX8 KLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5fyx A 1.80 BS03 CA A 3 D109 D111 D113 Y115 E120 D103 D105 D107 Y109 E114 Q9VWX8 KLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5fyx A 1.80 BS04 FD6 A 1 I51 Y52 F64 F72 F85 L89 T92 W103 L107 L182 I45 Y46 F58 F66 F79 L83 T86 W97 L101 L166 Q9VWX8 KLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSLG 5g08 A 1.52 BS01 CA A 1 D73 N75 D77 A79 E84 D70 N72 D74 A76 E81 Q9VWX8 KNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 5g08 A 1.52 BS02 CA A 2 D156 N158 D160 R162 E167 D153 N155 D157 R159 E164 Q9VWX8 KNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 5g08 A 1.52 BS03 CA A 3 D109 D111 D113 Y115 E120 D106 D108 D110 Y112 E117 Q9VWX8 KNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 5g08 A 1.52 BS04 Z80 A 1 Y52 F72 F85 T92 W103 Y49 F69 F82 T89 W100 Q9VWX8 KNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALS 5ghy B 2.10 BS01 CED B 1 A69 S70 Y105 S130 N132 H166 N170 K234 T235 G236 A237 R244 A38 S39 Y72 S97 N99 H133 N137 K201 T202 G203 A204 R210 3.5.2.6 P00808 DDFAKLEEQFDAKLGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFHPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMKALN 5ghy A 2.10 BS01 CED A 1 A69 S70 Y105 S130 N132 H166 N170 T235 G236 A237 R244 A38 S39 Y72 S97 N99 H133 N137 T202 G203 A204 R210 3.5.2.6 P00808 DDFAKLEEQFDAKLGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFHPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMKALN 5ghz B 1.93 BS01 CED B 1 A69 S70 Y105 S130 N132 N170 T235 G236 A237 R244 A38 S39 Y72 S97 N99 N137 T202 G203 A204 R210 3.5.2.6 P00808 DDFAKLEEQFDAKLGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFHPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMKALN 5ghz A 1.93 BS01 CED A 1 A69 S70 Y105 S130 N132 N170 K234 T235 G236 A237 R244 A38 S39 Y72 S97 N99 N137 K201 T202 G203 A204 R210 3.5.2.6 P00808 DDFAKLEEQFDAKLGIFALDTGTNRTVAYRPDERFAFASTIKALTVGVLLQQKSIEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGPESLKKELRKIGDEVTNPERFHPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRELLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSRDKKDAKYDDKLIAEATKVVMKALN 5goe A 1.80 BS01 GDP A 1 S85 S86 G87 K88 S89 S90 G106 N237 R238 D240 S284 A285 K286 S82 S83 G84 K85 S86 S87 G103 N220 R221 D223 S267 A268 K269 3.6.5.-,3.6.5.- Q8IWA4 PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFLP 5gof A 1.60 BS01 GTP A 1 T84 S85 S86 G87 K88 S89 S90 G106 N237 R238 D240 S284 A285 K286 T81 S82 S83 G84 K85 S86 S87 G103 N225 R226 D228 S272 A273 K274 3.6.5.-,3.6.5.- Q8IWA4 PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHAGCLVRVFWPKAKCALLRDDLVLVDSPGTDELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFLPS 5gof A 1.60 BS02 ZN A 1 C111 H144 H147 C156 C108 H141 H144 C147 3.6.5.-,3.6.5.- Q8IWA4 PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHAGCLVRVFWPKAKCALLRDDLVLVDSPGTDELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFLPS 5gxu A 2.30 BS01 FMN A 1 T111 Q112 T113 G114 T115 A116 A166 T167 Y168 G169 G171 L204 G205 N206 Y209 H211 F212 N213 D239 T9 Q10 T11 G12 T13 A14 A64 T65 Y66 G67 G69 L102 G103 N104 Y107 H109 F110 N111 D137 1.6.2.4 Q9SUM3 KKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILYTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 5gxu A 2.30 BS02 FAD A 1 H351 L414 S416 Q458 R489 F490 Y491 S492 T507 C508 A509 V511 E513 M515 R519 H521 G523 V524 C525 S526 T570 D709 W711 H208 L255 S257 Q299 R330 F331 Y332 S333 T348 C349 A350 V352 E354 M356 R360 H362 G364 V365 C366 S367 T411 D550 W552 1.6.2.4 Q9SUM3 KKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILYTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 5gxu B 2.30 BS01 FAD B 1 H351 L414 S415 S416 Q458 R489 F490 Y491 S492 T507 C508 A509 V511 E513 M515 R519 H521 G523 V524 C525 S526 T570 W711 H48 L97 S98 S99 Q141 R172 F173 Y174 S175 T190 C191 A192 V194 E196 M198 R202 H204 G206 V207 C208 S209 T253 W394 1.6.2.4 Q9SUM3 YTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 5h0r F 3.90 BS01 NUC H 1 N912 A962 S964 Q1095 K1098 N881 A931 S933 Q1056 K1059 A0A0S1LIW6 27914893 LHNTIFSETRKFTRESFKEIEHLTARLANDSVARHDFLFNTSIALISDYSGEDSNGNQLQATITIPNEIINPKEYDPSDYPLAEDESFFKQGHKYDYLVTFRAGSLTNTYEPKTKMYKLHAALDKLMHVRQRKSRFADLWRELCAVIASLDVWYQTTNYPLRTYVKLLFHRGDEFPFYESPSQDRIIFNDKSVASILPTFVYTCCQVGTAIMSGILTHVESIVAMNHFLHCAKDSYIDEKLKIKGIGRSWYQEALHNVGQATVPVWSQFNEVIGHRRKSTSEPHFVSSTFISLRAKRAELLYPEFNAYINRAIQLSKTQNDVANYYAACRAMTNDGTFLATLTELSLDAAVFPRIEQRLVTRPAVLMSNTRHESLKQKYTNGVGSIAQSYLSSFTDEIAKRVNGIHHDEAWLNFLTTSIVMQAVFAREYRTPERIFKSLKAPIKLVERQQSDRRQRAISGLDNDRLFLSFMPYTIGKQIYELNDNAAQGKQAGNAFDIGEMLYWTSQRNVLLSSIDVAGMDASVTTNTKDIYNTFVLDVASKCTVPRFGPYYAKNMEVFEVGKRQSQVRYVNAAWQACALEAADSQTSTSYESEIFGQVKNAEGTYPSGRADTSTHHTVLLQGLVRGNELKRASDGKNSCLATIKILGDDIMEIFQGSESDTYDHAMSNANILNESGFATTAELSQNSIVLLQQLVVNGTFWGFADRISLWTREDTKDIGRLNLAMMELNALIDDLVFRVRRPEGLKMLGFFCGAICLRRFTLSVDNKLYDSTYNNLSKYMTLIKYDKNPDFDSTLMSLILPLAWLFMPRGGEYPAYPFERRDGTFTEDESMFTARGAYKRRLLYDVSNIREMIQQNSMALDDDLLHEYGFTGALLLIDLNILDLIDEVKKEDISPVKVSELATSLEQLGKLGEREKSRRAASDLKIRGHALSNDIVYGYGLQEKIQKSAMAKRVSSRLHDVIVAKTRDYKISTIPADALRLHEFEVEDVTVDLLPHAKHTSYSSLAYNMSFGSDGWFAFALLGGLDRSANLLRLDVASIRGNYHKFSYDDPVFKQGYKIYKSDATLLNDFFTAISAGPKEQGILLRAFAYYSLYGNVEYHYVLSPRQLFFLSDNPVSAERLVRIPPKYYVSTQCRALYNIFSYLHILRSIANNWGKRLKMVLHPGLIAYVRGTSQGAILPEA 5h0r F 3.90 BS02 NUC I 1 R993 S995 R997 K1098 K1101 R954 S956 R958 K1059 K1062 A0A0S1LIW6 27914893 LHNTIFSETRKFTRESFKEIEHLTARLANDSVARHDFLFNTSIALISDYSGEDSNGNQLQATITIPNEIINPKEYDPSDYPLAEDESFFKQGHKYDYLVTFRAGSLTNTYEPKTKMYKLHAALDKLMHVRQRKSRFADLWRELCAVIASLDVWYQTTNYPLRTYVKLLFHRGDEFPFYESPSQDRIIFNDKSVASILPTFVYTCCQVGTAIMSGILTHVESIVAMNHFLHCAKDSYIDEKLKIKGIGRSWYQEALHNVGQATVPVWSQFNEVIGHRRKSTSEPHFVSSTFISLRAKRAELLYPEFNAYINRAIQLSKTQNDVANYYAACRAMTNDGTFLATLTELSLDAAVFPRIEQRLVTRPAVLMSNTRHESLKQKYTNGVGSIAQSYLSSFTDEIAKRVNGIHHDEAWLNFLTTSIVMQAVFAREYRTPERIFKSLKAPIKLVERQQSDRRQRAISGLDNDRLFLSFMPYTIGKQIYELNDNAAQGKQAGNAFDIGEMLYWTSQRNVLLSSIDVAGMDASVTTNTKDIYNTFVLDVASKCTVPRFGPYYAKNMEVFEVGKRQSQVRYVNAAWQACALEAADSQTSTSYESEIFGQVKNAEGTYPSGRADTSTHHTVLLQGLVRGNELKRASDGKNSCLATIKILGDDIMEIFQGSESDTYDHAMSNANILNESGFATTAELSQNSIVLLQQLVVNGTFWGFADRISLWTREDTKDIGRLNLAMMELNALIDDLVFRVRRPEGLKMLGFFCGAICLRRFTLSVDNKLYDSTYNNLSKYMTLIKYDKNPDFDSTLMSLILPLAWLFMPRGGEYPAYPFERRDGTFTEDESMFTARGAYKRRLLYDVSNIREMIQQNSMALDDDLLHEYGFTGALLLIDLNILDLIDEVKKEDISPVKVSELATSLEQLGKLGEREKSRRAASDLKIRGHALSNDIVYGYGLQEKIQKSAMAKRVSSRLHDVIVAKTRDYKISTIPADALRLHEFEVEDVTVDLLPHAKHTSYSSLAYNMSFGSDGWFAFALLGGLDRSANLLRLDVASIRGNYHKFSYDDPVFKQGYKIYKSDATLLNDFFTAISAGPKEQGILLRAFAYYSLYGNVEYHYVLSPRQLFFLSDNPVSAERLVRIPPKYYVSTQCRALYNIFSYLHILRSIANNWGKRLKMVLHPGLIAYVRGTSQGAILPEA 5h13 A 1.90 BS01 LQA A 1 Q94 P95 F97 N146 Y148 N194 Y365 R367 R414 Q29 P30 F32 N75 Y77 N123 Y286 R288 R335 O75530 28072869 GILENLYFQGKKCKYSFKCVNSLKEDHNQPLFGVQFNWHLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h14 A 1.90 BS01 III D 1 W103 H104 S105 K106 E107 D109 V112 L123 E125 Y154 S159 H160 P161 P177 R201 L246 L247 L315 G316 D317 L318 K332 M336 F372 W373 Q374 L391 E392 E394 R420 W28 H29 S30 K31 E32 D34 V37 L48 E50 Y79 S84 H85 P86 P102 R126 L171 L172 L240 G241 D242 L243 K257 M261 F297 W298 Q299 L316 E317 E319 R345 O75530 28072869 KKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h14 A 1.90 BS02 LQB A 1 F97 Y148 N194 L240 D310 Y365 R367 R414 F22 Y73 N119 L165 D235 Y290 R292 R339 O75530 28072869 KKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h14 B 1.90 BS01 III C 1 W103 H104 S105 K106 E107 D109 V112 L135 Y154 T158 S159 H160 P161 P177 I178 P200 R201 L246 L247 L315 G316 D317 L318 K332 M336 L353 F372 W373 Q374 L391 E392 E394 R420 W27 H28 S29 K30 E31 D33 V36 L59 Y78 T82 S83 H84 P85 P101 I102 P124 R125 L170 L171 L232 G233 D234 L235 K249 M253 L270 F289 W290 Q291 L308 E309 E311 R337 O75530 28072869 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h14 B 1.90 BS02 LQB B 1 F97 Y148 N194 L240 D310 Y365 R367 F21 Y72 N118 L164 D227 Y282 R284 O75530 28072869 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h15 A 2.27 BS01 III C 1 W103 H104 S105 E107 D109 V112 L123 Y154 T158 S159 H160 P161 P177 I178 R201 L246 L315 G316 D317 L318 M336 L353 F372 W373 Q374 L391 E392 E394 R420 W26 H27 S28 E30 D32 V35 L46 Y77 T81 S82 H83 P84 P100 I101 R124 L169 L231 G232 D233 L234 M252 L269 F288 W289 Q290 L307 E308 E310 R336 O75530 28072869 CKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h15 A 2.27 BS02 LQD A 1 F97 Y148 N194 E238 L240 D310 Y365 R367 R414 F20 Y71 N117 E161 L163 D226 Y281 R283 R330 O75530 28072869 CKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h15 B 2.27 BS01 III D 1 W103 H104 S105 K106 E107 D109 V112 L123 E125 Y154 T158 S159 H160 P161 P177 P200 R201 L246 L247 L315 G316 D317 L318 K332 M336 F372 W373 Q374 L391 E392 E394 R420 W27 H28 S29 K30 E31 D33 V36 L47 E49 Y78 T82 S83 H84 P85 P101 P124 R125 L170 L171 L239 G240 D241 L242 K256 M260 F296 W297 Q298 L315 E316 E318 R344 O75530 28072869 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h15 B 2.27 BS02 LQD B 1 F97 Y148 N194 E238 L240 D310 Y365 R367 R414 F21 Y72 N118 E162 L164 D234 Y289 R291 R338 O75530 28072869 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h17 A 2.30 BS01 III B 1 W103 H104 S105 K106 E107 Y154 T158 S159 H160 R201 L246 L247 L315 G316 D317 L318 F372 W373 Q374 L391 E392 E394 R420 W27 H28 S29 K30 E31 Y78 T82 S83 H84 R125 L170 L171 L232 G233 D234 L235 F289 W290 Q291 L308 E309 E311 R337 O75530 28072869 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h17 A 2.30 BS02 LQE A 1 F97 Y148 N194 E238 M256 D310 Y365 R367 R414 F21 Y72 N118 E162 M180 D227 Y282 R284 R331 O75530 28072869 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h19 A 1.90 BS01 III B 1 W103 H104 S105 K106 E107 D109 L123 W152 Y154 S159 H160 P161 P177 I178 R201 L246 L247 L315 G316 D317 L318 C330 M336 F372 W373 Q374 V393 E394 R420 W26 H27 S28 K29 E30 D32 L46 W75 Y77 S82 H83 P84 P100 I101 R124 L169 L170 L233 G234 D235 L236 C248 M254 F290 W291 Q292 V311 E312 R335 O75530 28072869 CKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h19 A 1.90 BS02 LQF A 1 P95 F97 Y148 N194 K211 L240 D310 Y365 R367 R414 D430 P18 F20 Y71 N117 K134 L163 D228 Y283 R285 R329 D345 O75530 28072869 CKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h24 A 2.50 BS01 III C 1 W103 H104 S105 K106 E107 D109 V112 L123 E125 Y154 T158 S159 H160 P161 P177 I178 P200 R201 L246 L247 L315 G316 D317 L318 K332 M336 L353 F372 W373 Q374 L391 E392 E394 R420 W27 H28 S29 K30 E31 D33 V36 L47 E49 Y78 T82 S83 H84 P85 P101 I102 P124 R125 L170 L171 L239 G240 D241 L242 K256 M260 L277 F296 W297 Q298 L315 E316 E318 R344 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h24 A 2.50 BS02 LQG A 1 F97 Y148 N194 K211 L240 D310 Y365 R367 F21 Y72 N118 K135 L164 D234 Y289 R291 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h24 B 2.50 BS01 III D 1 W103 H104 S105 E107 D109 L123 Y154 S159 H160 P161 P177 I178 R201 L246 L247 L315 G316 D317 L318 M336 L353 F372 W373 Q374 L391 E392 E394 R420 W27 H28 S29 E31 D33 L47 Y78 S83 H84 P85 P101 I102 R125 L170 L171 L234 G235 D236 L237 M255 L272 F291 W292 Q293 L310 E311 E313 R339 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h24 B 2.50 BS02 LQG B 1 F97 Y148 N194 K211 L240 D310 Y365 R367 F21 Y72 N118 K135 L164 D229 Y284 R286 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h25 A 2.88 BS01 III C 1 W103 H104 S105 K106 E107 D109 P110 V112 L123 L135 Y154 S159 H160 P161 I178 P200 R201 L246 L247 L315 G316 D317 L318 K332 M336 L353 F372 W373 Q374 L391 E392 V393 E394 R420 W27 H28 S29 K30 E31 D33 P34 V36 L47 L59 Y78 S83 H84 P85 I102 P124 R125 L170 L171 L239 G240 D241 L242 K256 M260 L277 F296 W297 Q298 L315 E316 V317 E318 R344 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h25 A 2.88 BS02 LQH A 1 F97 N146 Y148 N194 Y365 R414 F21 N70 Y72 N118 Y289 R338 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h25 B 2.88 BS01 III D 1 W103 H104 S105 K106 E107 D109 L123 L135 Y154 T158 S159 H160 P161 P177 I178 R201 L246 L247 L315 G316 D317 L318 K332 M336 L353 F372 W373 Q374 L391 E392 V393 E394 R420 W27 H28 S29 K30 E31 D33 L47 L59 Y78 T82 S83 H84 P85 P101 I102 R125 L170 L171 L232 G233 D234 L235 K249 M253 L270 F289 W290 Q291 L308 E309 V310 E311 R337 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h25 B 2.88 BS02 LQH B 1 F97 N146 Y148 N194 Y365 R367 F21 N70 Y72 N118 Y282 R284 O75530 28092155 KCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5h3o A 3.50 BS01 PCG A 1 G559 E560 L561 S562 R575 T576 V579 K619 G449 E450 L451 S452 R465 T466 V469 K509 Q03611 RKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 5h3o B 3.50 BS01 PCG B 1 G559 E560 L561 S562 R575 T576 V579 K619 G449 E450 L451 S452 R465 T466 V469 K509 Q03611 RKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 5h3o C 3.50 BS01 PCG C 1 G559 E560 L561 S562 R575 T576 V579 K619 G449 E450 L451 S452 R465 T466 V469 K509 Q03611 RKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 5h3o D 3.50 BS01 PCG D 1 G559 E560 L561 S562 R575 T576 V579 K619 G449 E450 L451 S452 R465 T466 V469 K509 Q03611 RKYLANYTQDPSTDNFYYWTCVVTVAYIYNLLFVIARQVFNDLIGPSSQSLCRFYNTTQVECTYNMLTNMKEMPTYSQYPDLGWSKYWHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLDYILGWPIPYINWRGLPILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHWNACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNIEYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWFDYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKD 5h47 A 2.30 BS01 FSW A 1 R25 E37 L69 I72 Y88 W94 R24 E36 L68 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 A 2.30 BS02 FSW A 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 A 2.30 BS03 FSW A 3 R126 E138 M140 G149 T150 Y192 W198 R125 E137 M139 G148 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 A 2.30 BS04 FSW A 4 W166 R177 Q189 Y199 I227 M229 W245 W165 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 A 2.30 BS05 FSW A 5 R230 Q242 C244 D253 R255 P274 L276 W294 R229 Q241 C243 D252 R254 P273 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 A 2.30 BS06 FSW A 6 N22 L24 Y40 W44 W271 R277 E291 G303 N21 L23 Y39 W43 W270 R276 E290 G302 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 B 2.30 BS01 FSW B 1 R25 E37 L69 I72 Y88 W94 R24 E36 L68 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 B 2.30 BS02 FSW B 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 B 2.30 BS03 FSW B 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 B 2.30 BS04 FSW B 4 R177 Q189 Y199 I227 M229 W245 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 B 2.30 BS05 FSW B 5 R230 Q242 C244 R255 P274 L276 W294 R229 Q241 C243 R254 P273 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 B 2.30 BS06 FSW B 6 N22 L24 Y40 W44 R277 E291 N21 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 C 2.30 BS01 FSW C 1 R25 E37 L69 I72 Y88 W94 R24 E36 L68 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 C 2.30 BS02 FSW C 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 C 2.30 BS03 FSW C 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 C 2.30 BS04 FSW C 4 R177 Q189 T203 I227 W245 R176 Q188 T202 I226 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 C 2.30 BS05 FSW C 5 F220 R230 Q242 C244 D253 P274 L276 W294 F219 R229 Q241 C243 D252 P273 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 C 2.30 BS06 FSW C 6 L24 Y40 W44 R277 E291 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 D 2.30 BS01 FSW D 1 R25 E37 L39 L69 Y88 W94 R24 E36 L38 L68 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 D 2.30 BS02 FSW D 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 D 2.30 BS03 FSW D 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 D 2.30 BS04 FSW D 4 R177 Q189 Y199 I227 M229 W245 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 D 2.30 BS05 FSW D 5 R230 Q242 C244 D253 R255 L276 W294 R229 Q241 C243 D252 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 D 2.30 BS06 FSW D 6 L24 Y40 W44 W271 R277 E291 L23 Y39 W43 W270 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 E 2.30 BS01 FSW E 1 R25 E37 L69 Y88 W94 R24 E36 L68 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 E 2.30 BS02 FSW E 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 E 2.30 BS03 FSW E 3 R126 E138 M140 T150 I176 Y192 W198 R125 E137 M139 T149 I175 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 E 2.30 BS04 FSW E 4 R177 Q189 Y199 I227 M229 W245 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 E 2.30 BS05 FSW E 5 R230 Q242 C244 R255 P274 L276 W294 R229 Q241 C243 R254 P273 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 E 2.30 BS06 FSW E 6 L24 Y40 W44 R277 E291 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 F 2.30 BS01 FSW F 1 R25 E37 N46 L69 Y88 W94 R24 E36 N45 L68 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 F 2.30 BS02 FSW F 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 F 2.30 BS03 FSW F 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 F 2.30 BS04 FSW F 4 R177 Q189 E201 I227 M229 W245 R176 Q188 E200 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 F 2.30 BS05 FSW F 5 R230 Q242 R255 L276 W294 R229 Q241 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 F 2.30 BS06 FSW F 6 L24 Y40 W44 R277 E291 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 G 2.30 BS01 FSW G 1 R25 E37 N46 Y88 W94 R24 E36 N45 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 G 2.30 BS02 FSW G 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 G 2.30 BS03 FSW G 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 G 2.30 BS04 FSW G 4 Y168 R177 Q189 Y199 I227 M229 W245 Y167 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 G 2.30 BS05 FSW G 5 F220 R230 Q242 R255 P274 L276 W294 F219 R229 Q241 R254 P273 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 G 2.30 BS06 FSW G 6 L24 Y40 W44 W271 R277 E291 G303 L23 Y39 W43 W270 R276 E290 G302 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 H 2.30 BS01 FSW H 1 R25 E37 L69 I72 Y88 W94 R24 E36 L68 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 H 2.30 BS02 FSW H 2 R73 E85 Y95 G97 A98 L125 W141 W146 R72 E84 Y94 G96 A97 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 H 2.30 BS03 FSW H 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 H 2.30 BS04 FSW H 4 R177 Q189 Y199 I227 M229 W245 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 H 2.30 BS05 FSW H 5 R230 Q242 C244 R255 L276 W294 R229 Q241 C243 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 H 2.30 BS06 FSW H 6 N22 L24 Y40 W44 R277 E291 N21 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 I 2.30 BS01 FSW I 1 R25 E37 N46 L69 I72 Y88 W94 R24 E36 N45 L68 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 I 2.30 BS02 FSW I 2 R73 E85 Y95 G97 A98 L125 W141 W146 R72 E84 Y94 G96 A97 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 I 2.30 BS03 FSW I 3 R126 E138 M140 T150 Y192 W198 R125 E137 M139 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 I 2.30 BS04 FSW I 4 R177 Q189 T203 I227 M229 W245 R176 Q188 T202 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 I 2.30 BS05 FSW I 5 R230 Q242 C244 R255 L276 W294 R229 Q241 C243 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 I 2.30 BS06 FSW I 6 L24 Y40 W44 W271 R277 E291 L23 Y39 W43 W270 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 J 2.30 BS01 FSW J 1 R25 E37 L69 I72 Y88 W94 R24 E36 L68 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 J 2.30 BS02 FSW J 2 R73 E85 Y95 A98 L123 L125 W141 W146 R72 E84 Y94 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 J 2.30 BS03 FSW J 3 R126 E138 M140 T150 I176 Y192 W198 R125 E137 M139 T149 I175 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 J 2.30 BS04 FSW J 4 R177 Q189 I227 M229 W245 R176 Q188 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 J 2.30 BS05 FSW J 5 R230 Q242 D253 R255 L276 W294 R229 Q241 D252 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 J 2.30 BS06 FSW J 6 L24 Y40 W44 R277 E291 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 K 2.30 BS01 FSW K 1 R25 E37 Y88 W94 R24 E36 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 K 2.30 BS02 FSW K 2 R73 E85 Y95 G97 A98 L123 L125 W141 W146 R72 E84 Y94 G96 A97 L122 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 K 2.30 BS03 FSW K 3 R126 E138 M140 T150 I176 Y192 W198 R125 E137 M139 T149 I175 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 K 2.30 BS04 FSW K 4 R177 Q189 I227 M229 W245 R176 Q188 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 K 2.30 BS05 FSW K 5 F220 R230 Q242 C244 D253 R255 L276 W294 F219 R229 Q241 C243 D252 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 K 2.30 BS06 FSW K 6 L24 Y40 W44 W271 R277 E291 L23 Y39 W43 W270 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 L 2.30 BS01 FSW L 1 R25 E37 I72 Y88 W94 R24 E36 I71 Y87 W93 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 L 2.30 BS02 FSW L 2 R73 E85 Y95 G97 A98 L125 W141 W146 R72 E84 Y94 G96 A97 L124 W140 W145 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 L 2.30 BS03 FSW L 3 R126 E138 M140 G149 T150 Y192 W198 R125 E137 M139 G148 T149 Y191 W197 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 L 2.30 BS04 FSW L 4 R177 Q189 Y199 I227 M229 W245 R176 Q188 Y198 I226 M228 W244 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 L 2.30 BS05 FSW L 5 R230 Q242 D253 R255 L276 W294 R229 Q241 D252 R254 L275 W293 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5h47 L 2.30 BS06 FSW L 6 L24 Y40 W44 R277 E291 L23 Y39 W43 R276 E290 Q2UNX8 28041800 STPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE 5hcl A 1.50 BS01 5Y9 A 1 P82 F83 V87 L92 L94 N140 I146 P41 F42 V46 L51 L53 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5hhy A 1.70 BS01 PLR A 1 S81 G82 H83 W108 G156 S158 D183 V185 A186 Q208 K209 S76 G77 H78 W103 G151 S153 D178 V180 A181 Q203 K204 2.6.1.51,2.6.1.44 P21549 LLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKK 5hhy A 1.70 BS02 PLR B 1 Y260 T263 Y255 T258 2.6.1.51,2.6.1.44 P21549 LLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKK 5hhy B 1.70 BS01 PLR A 1 Y260 H262 T263 Y255 H257 T258 2.6.1.51,2.6.1.44 P21549 LLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKKK 5hhy B 1.70 BS02 PLR B 1 S81 G82 H83 W108 G156 S158 D183 V185 A186 Q208 K209 S76 G77 H78 W103 G151 S153 D178 V180 A181 Q203 K204 2.6.1.51,2.6.1.44 P21549 LLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKKK 5hje A 1.40 BS01 TPP A 1 A30 H66 G114 P115 L116 D155 G156 E160 N185 I187 S188 I189 I248 H261 A29 H65 G113 P114 L115 D154 G155 E159 N184 I186 S187 I188 I247 H260 2.2.1.1 P34736 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5hje A 1.40 BS02 CA A 1 D155 N185 I187 D154 N184 I186 2.2.1.1 P34736 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5hje A 1.40 BS03 I22 A 1 H27 H66 H100 I189 H261 G262 H26 H65 H99 I188 H260 G261 2.2.1.1 P34736 SSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF 5hjh A 1.88 BS01 FE A 1 H78 E82 H73 E77 B2J981 TLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh A 1.88 BS02 FE A 2 H51 H63 H46 H58 B2J981 TLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh B 1.88 BS01 FE A 1 H51 H63 H46 H58 B2J981 TLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh B 1.88 BS02 FE A 3 H78 E82 H73 E77 B2J981 TLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh C 1.88 BS01 FE C 1 H78 E82 H73 E77 B2J981 TLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh C 1.88 BS02 FE C 2 H51 H63 H46 H58 B2J981 TLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh D 1.88 BS01 FE C 1 H51 H63 H47 H59 B2J981 QTLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hjh D 1.88 BS02 FE C 3 H78 E82 H74 E78 B2J981 QTLLRNFGNVYDNPVLLDRSVTAPVTEGFNVVLASFQALYLQYQKHHFVVEGSEFYSLHEFFNESYNQVQDHIHEIGERLDGLGGVPVATFSKLAELTCFEQESEGVYSSRQMVENDLAAEQAIIGVIRRQAAQAESLGDRGTRYLYEKILLKTEERAYHLSHFLAKDSLTLGFVQAA 5hkf A 2.25 BS01 PRP A 1 R38 L71 G72 K95 E120 D121 T122 T124 T125 G126 N127 S128 R31 L64 G65 K88 E104 D105 T106 T108 T109 G110 N111 S112 2.4.2.10 P9WHK9 PDRAELAELVRRLSVVRVTLSSGREYYVDLRRATLHHRASALIGRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAIEAEGLRYRSVLGLADLGL 5hkf B 2.25 BS01 PRP B 1 R38 L71 G72 K95 E120 D121 T122 S123 T124 T125 G126 S128 R33 L66 G67 K90 E109 D110 T111 S112 T113 T114 G115 S117 2.4.2.10 P9WHK9 HHHHHIEGRHMAGPDRAELAELVRRLSVYVDLRRATLHHRASALIGRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKSARLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAIEAEGLRYRSVLGLADLG 5hki B 2.40 BS01 6ZJ B 1 L25 V35 T124 S128 L22 V32 T114 S118 2.4.2.10 P9WHK9 PDRAELAELVRRLSVVHGRVTLSSGREADYYVDLRRATLHHRASALIGRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKSRLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAIEAEGLRYRSVLGLADLGL 5hki C 2.40 BS01 6ZJ C 1 S26 T124 S128 S23 T114 S118 2.4.2.10 P9WHK9 PDRAELAELVRRLSVVHGRVTLSSGREADYYVDLRRATLHHRASALIGRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKSRLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAIEAEGLRYRSVLGLADLGL 5hkl A 1.90 BS01 PO4 A 1 T124 T125 G126 S128 T114 T115 G116 S118 2.4.2.10 P9WHK9 GPDRAELAELVRRLSVVHGRVTLSSGREADYYVDLRRATLHHRASALIGRLMRELTADWDYSVVGGLTLGADPVATAIMHAPGRPIDAFVVRKSLIEGSEVTGQRVLVVEDTSTTGNSALTAVHAVQDVGGEVVGVATVVDRATGAAEAIEAEGLRYRSVLGLADLGL 5hle A 2.90 BS01 ADP A 1 R32 P33 Q102 S104 S105 G106 K107 T108 H109 K114 R17 P18 Q87 S89 S90 G91 K92 T93 H94 K99 P20480 NTVMDLRGNIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFAIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKSNRHVAEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVKNINKSLSALGNVISALAEGTTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFAA 5hlg A 3.00 BS01 NUC I 1 Y17 R21 K32 L55 N56 S66 N67 T70 K74 R84 R92 Q93 Y15 R19 K30 L53 N54 S64 N65 T68 K72 R82 R90 Q91 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLETKYVFEELEQTLKHLIEK 5hlg A 3.00 BS02 NUC J 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 T35 S37 Q38 N65 T66 M70 R73 D88 K89 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLETKYVFEELEQTLKHLIEK 5hlg B 3.00 BS01 NUC I 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPQEFTEYDETKYVFEELEQTLKHLIE 5hlg B 3.00 BS02 NUC J 1 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPQEFTEYDETKYVFEELEQTLKHLIE 5hlg C 3.00 BS01 NUC K 1 Y17 R21 Q25 K32 L55 N56 S66 N67 T70 K74 R84 R92 L94 Y14 R18 Q22 K29 L52 N53 S63 N64 T67 K71 R81 R89 L91 28086264 EQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlg C 3.00 BS02 NUC L 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T34 S36 Q37 N64 T65 M69 R72 D87 K88 R89 28086264 EQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlg D 3.00 BS01 NUC K 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T39 S41 Q42 N69 T70 M74 R77 D92 K93 R94 28086264 CNMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPQDETKYVFEELEQTLKHLI 5hlg D 3.00 BS02 NUC L 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 Y19 R23 Q27 L57 N58 S68 N69 T72 K76 R86 R94 Q95 L96 28086264 CNMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPQDETKYVFEELEQTLKHLI 5hlg E 3.00 BS01 NUC M 1 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 L94 Y18 R22 L56 N57 S67 N68 T71 K75 R85 R87 R93 L95 28086264 NMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLDETKYVFEELEQTLKHLIE 5hlg E 3.00 BS02 NUC N 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T38 S40 Q41 N68 T69 M73 R76 D91 K92 R93 28086264 NMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLDETKYVFEELEQTLKHLIE 5hlg F 3.00 BS01 NUC M 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T38 S40 Q41 N68 T69 M73 R76 D91 K92 R93 28086264 NMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlg F 3.00 BS02 NUC N 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 Y18 R22 Q26 L56 N57 S67 N68 T71 K75 R85 R87 R93 Q94 L95 28086264 NMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlg G 3.00 BS01 NUC O 1 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 Y15 R19 L53 N54 S64 N65 T68 K72 R82 R90 Q91 L92 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLEYDETKYVFEELEQTLKHLIE 5hlg G 3.00 BS02 NUC P 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T35 S37 Q38 N65 T66 M70 R73 D88 K89 R90 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLEYDETKYVFEELEQTLKHLIE 5hlg H 3.00 BS01 NUC O 1 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T37 S39 Q40 N67 T68 M72 R75 D90 K91 R92 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPYDETKYVFEELEQTLKHLIE 5hlg H 3.00 BS02 NUC P 1 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPYDETKYVFEELEQTLKHLIE 5hlh A 3.00 BS01 NUC I 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 Y15 R19 Q23 L53 N54 S64 N65 T68 K72 R82 R90 Q91 L92 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCYDETKYVFEELEQTLKHLIEK 5hlh A 3.00 BS02 NUC J 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 T35 Y36 S37 Q38 N65 T66 M70 R73 D88 K89 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCYDETKYVFEELEQTLKHLIEK 5hlh B 3.00 BS01 NUC I 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLEYDETKYVFEELEQTLKHLIE 5hlh B 3.00 BS02 NUC J 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLEYDETKYVFEELEQTLKHLIE 5hlh C 3.00 BS01 NUC K 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R86 R92 L94 Y14 R18 Q22 L52 N53 S63 N64 T67 K71 R81 R83 R89 L91 28086264 EQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLI 5hlh C 3.00 BS02 NUC L 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T34 Y35 S36 Q37 N64 T65 M69 R72 D87 K88 R89 28086264 EQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLI 5hlh D 3.00 BS01 NUC K 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPDETKYVFEELEQTLKHLI 5hlh D 3.00 BS02 NUC L 1 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 Y17 R21 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPDETKYVFEELEQTLKHLI 5hlh E 3.00 BS01 NUC M 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 Y18 R22 Q26 L56 N57 S67 N68 T71 K75 R85 R93 Q94 L95 28086264 AMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPDETKYVFEELEQTLKHLI 5hlh E 3.00 BS02 NUC N 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T38 Y39 S40 Q41 N68 T69 M73 R76 D91 K92 R93 28086264 AMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPDETKYVFEELEQTLKHLI 5hlh F 3.00 BS01 NUC M 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlh F 3.00 BS02 NUC N 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlh G 3.00 BS01 NUC O 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R92 Q93 L94 Y15 R19 Q23 L53 N54 S64 N65 T68 K72 R82 R90 Q91 L92 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLTKYVFEELEQTLKHLI 5hlh G 3.00 BS02 NUC P 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T35 Y36 S37 Q38 N65 T66 M70 R73 D88 K89 R90 28086264 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLTKYVFEELEQTLKHLI 5hlh H 3.00 BS01 NUC O 1 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 T37 Y38 S39 Q40 N67 T68 M72 R75 D90 K91 R92 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hlh H 3.00 BS02 NUC P 1 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 Y17 R21 Q25 L55 N56 S66 N67 T70 K74 R84 R86 R92 Q93 L94 28086264 MKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYVFEELEQTLKHLIE 5hli A 2.05 BS01 CU A 1 Q-2 S-1 Q1 S2 28086264 QSNMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPDTTEYDETKYVFEELEQTLKHLIEK 5hli B 2.05 BS01 CU B 1 Q-2 S-1 Q1 S2 28086264 QSNMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLPQVFEELEQTLKHLIE 5hm1 A 2.96 BS01 III D 1 D32 A33 A34 F37 P47 T50 I51 L52 T53 N58 Y59 A60 P95 M96 Y100C D32 A33 A34 F37 P47 T50 I51 L52 T53 N58 Y59 A60 P98 M99 Y106 DVQLQESGGGLVQPGGSLRLSCAASGNIVSIDAAGWFRQAPGKQREPVATILTGGATNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCYAPMIYYGGRYSDYWGQGTQVTVS 5hm1 B 2.96 BS01 III E 1 D32 A33 A34 F37 P47 T50 I51 L52 T53 N58 Y59 A60 P95 M96 D32 A33 A34 F37 P47 T50 I51 L52 T53 N58 Y59 A60 P98 M99 DVQLQESGGGLVQPGGSLRLSCAASGNIVSIDAAGWFRQAPGKQREPVATILTGGATNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCYAPMIYYGGRYSDYWGQGTQVTVS 5hm1 C 2.96 BS01 III F 1 D32 A33 A34 F37 P47 T50 I51 L52 T53 N58 Y59 A60 Y93 M96 D32 A33 A34 F37 P47 T50 I51 L52 T53 N58 Y59 A60 Y96 M99 DVQLQESGGGLVQPGGSLRLSCAASGNIVSIDAAGWFRQAPGKQREPVATILTGGATNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCYAPMIYYGGRYSDYWGQGTQVTVS 5hnu A 2.00 BS01 NAP A 1 G22 T23 Y24 D50 Y55 H117 S166 N167 Q190 Y216 S217 L219 G220 S221 Q222 L236 A253 L268 A269 K270 S271 Y272 R276 Q279 N280 F306 G17 T18 Y19 D45 Y50 H112 S161 N162 Q185 Y211 S212 L214 G215 S216 Q217 L231 A248 L263 A264 K265 S266 Y267 R271 Q274 N275 F301 1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64,1.3.1.20 P42330 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYS 5hnu C 2.00 BS01 65D C 1 Y24 L54 Y55 H117 W227 F306 F311 Y19 L49 Y50 H112 W222 F301 F306 1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64,1.3.1.20 P42330 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYS 5hnu C 2.00 BS02 NAP C 1 G22 T23 Y24 D50 Y55 H117 S166 N167 Q190 Y216 S217 L219 G220 S221 Q222 L236 A253 L268 A269 K270 S271 Y272 R276 Q279 N280 F306 G17 T18 Y19 D45 Y50 H112 S161 N162 Q185 Y211 S212 L214 G215 S216 Q217 L231 A248 L263 A264 K265 S266 Y267 R271 Q274 N275 F301 1.1.1.357,1.1.1.112,1.1.1.188,1.1.1.239,1.1.1.64,1.3.1.20 P42330 QCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYS 5hnv A 1.41 BS01 ATP A 1 I29 G30 E31 V37 A50 L102 T118 Q119 F120 Y121 T125 K127 N128 Q172 I19 G20 E21 V27 A40 L92 T108 Q109 F110 Y111 T115 K117 N118 Q162 SNSLPSGYRFNEFEIQEAIGEGGFGIVYRAYDHQLERTIAIKEYMPTSLAKRNDDLSIGLRGERFGKTFQAGLNSFIQEARLLARFSHPGLLHVLRFWEENGTAYMGTQFYSGTTLKNLQAQQPEKIDEAWIRRLLPPLFSAINTIHQEGYLHRDISLDNIQIQESQLPVLLDFGSARKEIGNLSDETEIVLKPGFAPIEQYTEQGPWTDIYALGAVLHTLIVGSPPPVSVVRSIEDSYQPLTERRPAGYSPELLRTVDRALALKPEDRPQTIDEMAELLEHH 5hpb A 1.65 BS01 NDP A 1 V8 A9 I16 G17 G20 D21 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 S92 V115 G116 G117 S118 S119 Y121 T146 V8 A9 I16 G17 G20 D21 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 S92 V115 G116 G117 S118 S119 Y121 T146 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hpb A 1.65 BS02 63W A 1 I7 V8 A9 L22 E30 F31 F34 I60 P61 N64 L67 V115 Y121 T136 I7 V8 A9 L22 E30 F31 F34 I60 P61 N64 L67 V115 Y121 T136 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hpo A 1.80 BS01 CA A 1 E939 E941 T958 G961 D1054 E938 E940 T957 G960 D1053 Q8Y4J2 28089449 DGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hpo A 1.80 BS02 CEX A 1 D767 N770 G772 H774 Y782 Y783 F942 D766 N769 G771 H773 Y781 Y782 F941 Q8Y4J2 28089449 DGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hpo A 1.80 BS03 CEX A 2 E43 N44 G45 Q46 Y66 N69 W76 E42 N43 G44 Q45 Y65 N68 W75 Q8Y4J2 28089449 DGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hpo A 1.80 BS04 CEX A 3 Y5 W40 N72 N73 Y4 W39 N71 N72 Q8Y4J2 28089449 DGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hpq A 2.05 BS01 ACT A 1 W71 S91 R96 G142 T143 W59 S79 R84 G130 T131 4.2.1.51,4.2.1.91 Q01269 ESRLDRILESGVLRVATTGDYKPFSYRTEEGGYAGFDVDMAQRLAESLGAKLVVVPTSWPNLMRDFADDRFDIAMSGISINLERQRQAYFSIPYLRDGKTPITLCSEEARFQTLEQIDQPGVTAIVNPGGTNEKFARANLKKARILVHPDNVTIFQQIVDGKADLMMTDAIEARLQSRLHPELCAVHPQQPFDFAEKAYLLPRDEAFKRYVDQWLHIAEQSGLLRQRMEHWLEYRWPT 5hpr B 1.33 BS01 III A 1 V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 T30 V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28 T30 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hq5 A 1.60 BS01 64Q A 1 W81 P82 F83 V87 L92 L94 Y139 N140 I146 W40 P41 F42 V46 L51 L53 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5hq6 A 1.95 BS01 64R A 1 P82 V87 L92 L94 N140 I146 P41 V46 L51 L53 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPT 5hq7 A 1.90 BS01 64S A 1 W81 P82 F83 Q85 V87 L92 C136 Y139 N140 I146 W39 P40 F41 Q43 V45 L50 C94 Y97 N98 I104 O60885 MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTE 5hql A 2.53 BS01 CAP A 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 G394 G395 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 G394 G395 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKL 5hql A 2.53 BS02 MG A 1 K169 K192 D194 E195 K169 K192 D194 E195 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKL 5hql A 2.53 BS03 CAP B 1 E49 T54 N112 E49 T54 N112 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKL 5hql B 2.53 BS01 CAP A 1 T54 N112 T54 N112 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLK 5hql B 2.53 BS02 CAP B 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 A393 G394 G395 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 A393 G394 G395 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLK 5hql B 2.53 BS03 MG B 1 K167 K169 K192 D194 E195 K167 K169 K192 D194 E195 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLK 5hql C 2.53 BS01 CAP C 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 G394 G395 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 G394 G395 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKL 5hql C 2.53 BS02 MG C 1 K169 K192 D194 E195 K169 K192 D194 E195 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKL 5hql C 2.53 BS03 CAP E 1 T54 N112 T54 N112 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKL 5hql D 2.53 BS01 CAP D 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 A393 G394 G395 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 A393 G394 G395 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAK 5hql D 2.53 BS02 MG D 1 K169 K192 D194 E195 K169 K192 D194 E195 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAK 5hql D 2.53 BS03 CAP F 1 E49 T54 N112 E49 T54 N112 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAK 5hql E 2.53 BS01 CAP C 1 T54 N112 T54 N112 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLK 5hql E 2.53 BS02 CAP E 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 A393 G394 G395 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 S369 G370 G371 A393 G394 G395 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLK 5hql E 2.53 BS03 MG E 1 K169 K192 D194 E195 K169 K192 D194 E195 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLK 5hql F 2.53 BS01 CAP D 1 T54 N112 T54 N112 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFADHREFARAFESFPQDADKLYPNWRAK 5hql F 2.53 BS02 CAP F 1 I165 K167 K169 K192 E195 H288 R289 H292 H322 K330 S369 G370 G371 G394 G395 I165 K167 K169 K192 E195 H288 R289 H292 H322 K330 S369 G370 G371 G394 G395 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFADHREFARAFESFPQDADKLYPNWRAK 5hql F 2.53 BS03 MG F 1 K169 K192 D194 E195 H288 K169 K192 D194 E195 H288 4.1.1.39 Q6N0W9 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFVAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKAEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFADHREFARAFESFPQDADKLYPNWRAK 5hqm A 1.95 BS01 CAP A 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 M331 S369 G370 G371 G394 G395 I163 K165 K167 K190 D192 E193 H286 R287 H320 K328 M329 S367 G368 G369 G392 G393 4.1.1.39 P04718 QSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLGVEDT 5hqm A 1.95 BS02 MG A 1 K169 K192 D194 E195 K167 K190 D192 E193 4.1.1.39 P04718 QSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLGVEDT 5hqm A 1.95 BS03 CAP B 1 T54 N112 T52 N110 4.1.1.39 P04718 QSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRAKLGVEDT 5hqm B 1.95 BS01 CAP A 1 E49 T54 N112 E49 T54 N112 4.1.1.39 P04718 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRA 5hqm B 1.95 BS02 CAP B 1 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 M331 S369 G370 G371 G394 G395 I165 K167 K169 K192 D194 E195 H288 R289 H322 K330 M331 S369 G370 G371 G394 G395 4.1.1.39 P04718 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRA 5hqm B 1.95 BS03 MG B 1 K169 K192 D194 E195 H288 K169 K192 D194 E195 H288 4.1.1.39 P04718 MDQSNRYANLNLKESELIAGGRHVLCAYIMKPKAGFGNFIQTAAHFAAESSTGTNVEVSTTDDFTRGVDALVYEVDEANSLMKIAYPIELFDRNVIDGRAMIASFLTLTIGNNQGMGDVEYAKMYDFYVPPAYLKLFDGPSTTIKDLWRVLGRPVINGGFIVGTIIKPKLGLRPQPFANACYDFWLGGDFIKNDEPQGNQVFAPFKDTVRAVADAMRRAQDKTGEAKLFSFNITADDHYEMLARGEFILETFADNADHIAFLVDGYVAGPAAVTTARRAFPKQYLHYHRAGHGAVTSPQSKRGYTAFVLSKMARLQGASGIHTGTMGFGKMEGEAADRAIAYMITEDAADGPYFHQEWLGMNPTTPIISGGMNALRMPGFFDNLGHSNLIMTAGGGAFGHVDGGAAGAKSLRQAEQCWKQGADPVEFAKDHREFARAFESFPQDADKLYPNWRA 5hqy A 1.46 BS01 NDP A 1 V8 A9 I16 G17 G20 D21 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 S92 V115 G116 G117 S118 S119 V120 Y121 T146 V8 A9 I16 G17 G20 D21 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 S92 V115 G116 G117 S118 S119 V120 Y121 T146 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hqy A 1.46 BS02 63Y A 1 I7 V8 A9 L22 E30 F31 F34 P61 N64 V115 I7 V8 A9 L22 E30 F31 F34 P61 N64 V115 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hqy A 1.46 BS03 63Y A 2 I7 V8 A9 D21 L22 E30 F31 F34 S59 V115 I7 V8 A9 D21 L22 E30 F31 F34 S59 V115 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hqz A 1.46 BS01 NDP A 1 V8 A9 I16 G17 G20 D21 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 S92 V115 G116 G117 S118 S119 V120 Y121 T146 V8 A9 I16 G17 G20 D21 L22 G53 K54 K55 T56 S59 L75 S76 R77 E78 R91 S92 V115 G116 G117 S118 S119 V120 Y121 T146 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hqz A 1.46 BS02 64J A 1 I7 V8 A9 L22 E30 F31 F34 P61 N64 L67 V115 Y121 I7 V8 A9 L22 E30 F31 F34 P61 N64 L67 V115 Y121 1.5.1.3 P00374 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 5hrq B 1.28 BS01 III A 1 Q4 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 T30 Q4 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 T30 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq B 1.28 BS02 III C 1 F25 T27 F25 T27 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq B 1.28 BS03 III I 1 F1 V2 H5 F1 V2 H5 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq D 1.28 BS01 III C 1 Q4 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 T27 K29 T30 Q4 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 T27 K29 T30 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq D 1.28 BS02 III G 1 F1 V2 H5 F1 V2 H5 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq H 1.28 BS01 III E 1 F25 Y26 F25 Y26 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq H 1.28 BS02 III G 1 Q4 C7 L11 A14 L15 V18 C19 R22 G23 F25 Y26 T30 Q4 C7 L11 A14 L15 V18 C19 R22 G23 F25 Y26 T30 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5hrq H 1.28 BS03 III K 1 V2 H5 V2 H5 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 5huh A 2.50 BS01 MG A 1 D60 E173 D52 E165 6.3.1.5 A0A0H3BZ89 MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYELADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFADFWK 5huh B 2.50 BS01 MG B 1 D60 E173 D52 E165 6.3.1.5 A0A0H3BZ89 MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFADFWK 5hxm A 1.90 BS01 MG A 1 E370 D372 D376 E370 D372 D376 3.2.1.177 28089449 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hxm A 1.90 BS02 CA A 1 E939 E941 T958 G961 D1054 E939 E941 T958 G961 D1054 3.2.1.177 28089449 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hxm A 1.90 BS03 GLC A 1 H954 G965 W1020 N1052 H954 G965 W1020 N1052 3.2.1.177 28089449 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hxm A 1.90 BS04 GLC A 2 D967 V996 E997 G1050 D967 V996 E997 G1050 3.2.1.177 28089449 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hxm A 1.90 BS05 GLC A 3 D767 N770 H774 Y782 Y783 D767 N770 H774 Y782 Y783 3.2.1.177 28089449 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hxm A 1.90 BS06 GLC A 4 N770 E941 T950 T960 N770 E941 T950 T960 3.2.1.177 28089449 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5hz5 A 1.40 BS01 65X A 1 F19 M23 L32 M35 A39 P41 T56 A78 D79 I107 R109 V118 C120 R129 Y131 F18 M22 L31 M34 A38 P40 T55 A77 D78 I106 R108 V117 C119 R128 Y130 Q01469 27658368 ATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE 5itc A 2.00 BS01 RET A 1 Y91 W94 T97 T98 L101 M126 W146 S149 T150 M153 W190 Y193 P194 W197 D220 A223 K224 Y81 W84 T87 T88 L91 M116 W136 S139 T140 M143 W180 Y183 P184 W187 D210 A213 K214 Q18DH8 28089451 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5itc B 2.00 BS01 RET B 1 Y91 W94 T98 M126 G130 W146 S149 T150 M153 W190 Y193 P194 W197 D220 A223 K224 Y81 W84 T88 M116 G120 W136 S139 T140 M143 W180 Y183 P184 W187 D210 A213 K214 Q18DH8 28089451 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5itc C 2.00 BS01 RET C 1 Y91 W94 T98 L101 M126 G130 W146 S149 T150 M153 W190 Y193 P194 W197 D220 K224 Y81 W84 T88 L91 M116 G120 W136 S139 T140 M143 W180 Y183 P184 W187 D210 K214 Q18DH8 28089451 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5ite A 2.18 BS01 RET A 1 Y91 W94 T97 T98 L101 M126 G130 W146 S149 T150 M153 W190 Y193 P194 W197 A223 K224 Y81 W84 T87 T88 L91 M116 G120 W136 S139 T140 M143 W180 Y183 P184 W187 A213 K214 Q18DH8 28089451 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5ite B 2.18 BS01 RET B 1 Y91 W94 T98 L101 M126 G130 W146 S149 T150 M153 W190 Y193 P194 W197 A223 K224 Y81 W84 T88 L91 M116 G120 W136 S139 T140 M143 W180 Y183 P184 W187 A213 K214 Q18DH8 28089451 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5ite C 2.18 BS01 RET C 1 Y91 W94 T98 L101 M126 W146 S149 T150 M153 W190 Y193 P194 W197 D220 A223 K224 Y81 W84 T88 L91 M116 W136 S139 T140 M143 W180 Y183 P184 W187 D210 A213 K214 Q18DH8 28089451 LGVEGEGIWLALGTIGMLLGMLYFIADGLDVQDPRQKEFYVITILIPAIAAASYLSMFFGFGLTEVSLANGRVVDVYWARYADWLFTTPLLLLDIGLLAGASQRDIGALVGIDAFMIVTGLVATLTKVVVARYAFWTISTISMVFLLYYLVAVFGEAVSDADEDTRSTFNALRNIILVTWAIYPVAWLVGTEGLALTGLYGETLLFMVLDLVAKVGFGFILLRSRAIM 5j58 A 2.80 BS01 MET A 1 P247 I248 Y250 D287 W474 A477 L478 Y481 I519 H523 T549 K550 P10 I11 Y13 D50 W237 A240 L241 Y244 I282 H286 T312 K313 6.1.1.10 Q38C91 27788467 VEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDESFLTPQNITDGVDKDGNPCKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRARATLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLVDDFNELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEGEVLFSKRST 5j58 B 2.80 BS01 N56 B 1 I248 Y250 D287 H289 G290 L456 V471 Y472 V473 W474 D476 A477 F522 H523 I17 Y19 D56 H58 G59 L220 V235 Y236 V237 W238 D240 A241 F286 H287 6.1.1.10 Q38C91 27788467 GPGSMKVEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDESFLTPQNITDGNPCKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRARATLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLVDDFNELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKDRKKISKSLGNVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEGEVLFSKRST 5j59 A 2.40 BS01 MET A 1 P247 I248 Y250 D287 W474 A477 L478 Y481 I519 H523 K550 P10 I11 Y13 D50 W237 A240 L241 Y244 I282 H286 K313 6.1.1.10 Q38C91 27788467 VEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDESFLTPQNITDGVDKDGNPCKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRARATLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLVDDFNELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKNVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEVLFSKRS 5j59 B 2.40 BS01 N93 B 1 I248 Y250 D287 H289 G290 L456 Y472 V473 W474 A477 Y481 F522 H523 I17 Y19 D56 H58 G59 L222 Y238 V239 W240 A243 Y247 F288 H289 6.1.1.10 Q38C91 27788467 GPGSMKVEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDESFLTPQNITDGVDNPCKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRARATLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLVDDFNELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKDRKKISKSLGNVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEGEVLFSKRST 5j5a A 2.70 BS01 MET A 1 I248 Y250 D287 W474 A477 L478 Y481 I519 H523 K550 I11 Y13 D50 W237 A240 L241 Y244 I282 H286 K313 6.1.1.10 Q38C91 27788467 VEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDESFLTPQNITDGVDKDGNPCKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRARATLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLVDDFNELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKNVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEVLFSKRST 5j5a B 2.70 BS01 756 B 1 I248 Y250 D287 H289 G290 Y472 V473 D476 L478 Y481 F522 H523 I17 Y19 D56 H58 G59 Y228 V229 D232 L234 Y237 F278 H279 6.1.1.10 Q38C91 27788467 GPGSMKVEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCFEQMDYSIDYFIRTTNEQHKAVVKELWTKLEQKGDIYLGRYEGWYSISDEFLTPQNKVSLESGHVVTWVSEENYMFRLSAFRERLLEWYHANPGCIVPEFRRREVIRAVEKGLPDLSVSRARATLHNWAIPVPGNPDHCVYVWLDALTNYLTGSRLRVDESGKEVSLVDDFNELERFPADVHVIGKDILKFHAIYWPAFLLSAGLPLPKKIVAHGWWTKDRKKISKSLGNVFDPVEKAEEFGYDALKYFLLRESGFSDDGDYSDKNMIARLNGELADTLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAPWKLVKTDPERLRTVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHRKGIENFEFGAVPPGTRLGPAVEGEVLFSKRST 5j6a A 2.05 BS01 P46 A 1 L252 N255 R258 A259 E262 S263 E265 D290 G294 V295 L303 L346 T354 L230 N233 R236 A237 E240 S241 E243 D268 G272 V273 L281 L310 T318 2.7.11.2 Q15119 28085286 ASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSCEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPV 5j71 A 1.65 BS01 P35 A 1 L252 N255 R258 A259 E262 S263 D290 G294 V295 L303 T354 L224 N227 R230 A231 E234 S235 D262 G266 V267 L275 T307 2.7.11.2 Q15119 28085286 SLAGAPKYIEHFSKFSPSPLSMKQFLDCEKTSFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYDWC 5ja0 F 1.90 BS01 FPP F 1 Y10 K57 N59 R60 L62 T63 V66 S205 F206 F239 V340 G343 L344 K347 Y1 K43 N45 R46 L48 T49 V52 S191 F192 F225 V321 G324 L325 K328 2.5.1.10,2.5.1.1 P14324 YAQEKQDFVQHFSQIVRVLTEPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY 5jiw A 1.73 BS01 BGC A 1 Y250 E373 Y250 E372 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS02 GLC A 1 E373 N374 P375 E372 N373 P374 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS03 GLC A 2 G343 F366 D369 N374 F376 G343 F366 D369 N373 F375 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS04 GLC A 3 F251 G343 F366 F251 G343 F366 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS05 GLC A 4 Q256 W258 H294 E340 Q256 W258 H294 E340 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS06 GLC A 5 Y59 H394 N395 W473 Y59 H393 N394 W472 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS07 GLC A 6 S57 Y59 Q60 N464 P466 S57 Y59 Q60 N463 P465 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS08 GLC A 7 Y54 Q60 Y54 Q60 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS09 GLC A 8 F62 K148 G153 D221 F62 K148 G153 D221 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS10 GLC A 9 G53 Y54 Y101 G53 Y54 Y101 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS11 GLC A 10 G53 Y54 G55 D56 G98 G53 Y54 G55 D56 G98 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS12 GLC A 11 Y54 P469 S470 Y54 P468 S469 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jiw A 1.73 BS13 CO3 A 1 W316 K318 W316 K318 2.4.1.25 O87172 28097217 MELPRAFGLLLHPTSLPGPYGVGVLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGALKAEAEALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKALELFHLVRIAHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQKIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDGMENPFLPHNYPAHGRVVVYTGTHNNDTTLGWYRTATPHEKAFMARYLADWGITFREEEEVPWALMHLGMKSVARLAVYPVQDVLALGSEARMNYPGRPSGNWAWRLLPGELSPEHGARLRAMAEATERL 5jrw B 3.30 BS01 MG B 1 D175 R253 H257 D159 R237 H241 Q9WZ31 LVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLERILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRRVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGMNFEYMPELRWKWGYPVVLAVMGVIAVIMVVYFKKKK 5jrw C 3.30 BS01 MG B 2 G312 N314 G297 N299 Q9WZ31 TLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLERILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRRVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGMNFEYMPELRWKWGYPVVLAVMGVIAVIMVVYFKKKK 5jrw E 3.30 BS01 MG D 1 D175 D179 D164 D168 Q9WZ31 LPPGTLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLERILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRRVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGMNFEYMPELRWKWGYPVVLAVMGVIAVIMVVYFKKKK 5jrw E 3.30 BS02 MG E 1 L12 P14 L1 P3 Q9WZ31 LPPGTLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLERILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRRVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGMNFEYMPELRWKWGYPVVLAVMGVIAVIMVVYFKKKK 5jtg B 3.05 BS01 MG B 1 D189 D193 D175 D179 Q9WZ31 GTLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLEKILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRKVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGYPVVLAVMGVIAVIMVVYFKKKK 5jtg E 3.05 BS01 MG E 1 D175 D179 D160 D164 Q9WZ31 TLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSSTPTWINITGIHRTDVVQRVGEFFGIHPLVLEKILNVHQRPKVEFFENYVFIVLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNRGIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETVQRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRKVYDHTIQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIAGIYGYPVVLAVMGVIAVIMVVYFKKKK 5k0m A 1.83 BS01 6PU A 1 P95 F97 Y148 N194 E238 L240 D310 Y365 R367 R414 D430 P14 F16 Y67 N113 E157 L159 D229 Y284 R286 R333 D349 O75530 FKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRL 5kmp A 3.20 BS01 FAD A 1 G10 G12 Y13 N37 K38 Y43 T45 T46 D79 T80 V81 L107 G108 I126 F165 T166 N265 I267 G298 D299 T315 A316 Q317 A319 G8 G10 Y11 N35 K36 Y41 T43 T44 D77 T78 V79 L105 G106 I124 F163 T164 N263 I265 G296 D297 T313 A314 Q315 A317 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAEFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKK 5kmp B 3.20 BS01 FAD B 1 G10 G12 Y13 N37 K38 Y43 T45 T46 H49 V81 L107 G108 I126 F165 T166 N265 I267 G298 D299 P314 T315 A316 Q317 T349 K376 G8 G10 Y11 N35 K36 Y41 T43 T44 H47 V79 L105 G106 I124 F163 T164 N263 I265 G296 D297 P312 T313 A314 Q315 T347 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAEFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKKG 5kmq A 2.70 BS01 FAD A 1 G10 G12 Y13 G14 N37 K38 Y43 T45 T46 H49 V81 L107 G108 I126 F165 T166 N265 I267 G298 D299 P314 T315 A316 Q317 K376 G8 G10 Y11 G12 N35 K36 Y41 T43 T44 H47 V79 L105 G106 I124 F163 T164 N263 I265 G296 D297 P312 T313 A314 Q315 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLEDMRYLYLIGGLSLVLK 5kmq B 2.70 BS01 FAD B 1 G10 G12 Y13 G14 N37 K38 Y43 T45 T46 H49 D79 T80 V81 G106 L107 G108 I126 F165 T166 N265 I267 G298 D299 P314 T315 A316 Q317 T349 K376 G8 G10 Y11 G12 N35 K36 Y41 T43 T44 H47 D77 T78 V79 G104 L105 G106 I124 F163 T164 N263 I265 G296 D297 P312 T313 A314 Q315 T347 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLEDMRYLYLIGGLSLVLK 5kmq C 2.70 BS01 FAD C 1 G10 G12 Y13 N37 K38 Y43 T45 T46 D79 T80 V81 L107 G108 I126 F165 T166 G298 D299 P314 T315 A316 Q317 A319 G8 G10 Y11 N35 K36 Y41 T43 T44 D77 T78 V79 L105 G106 I124 F163 T164 G296 D297 P312 T313 A314 Q315 A317 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRMTPFKPHIRGTVASLGRNDAIVYGHAASWLKKLEDMRYLYLIGGLSLVLKK 5kmq D 2.70 BS01 FAD D 1 G10 G12 Y13 N37 K38 Y43 T45 T46 H49 D79 T80 V81 L107 G108 I126 I267 G298 D299 P314 T315 A316 Q317 A319 K376 G8 G10 Y11 N35 K36 Y41 T43 T44 H47 D77 T78 V79 L105 G106 I124 I265 G296 D297 P312 T313 A314 Q315 A317 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLEDMRYLYLIGGLSLVLKK 5kmr B 3.00 BS01 FAD B 1 G10 G12 Y13 G14 N37 K38 Y43 T45 T46 H49 D79 T80 V81 L107 G108 I126 T166 N265 I267 G298 D299 P314 T315 A316 Q317 A319 K376 G8 G10 Y11 G12 N35 K36 Y41 T43 T44 H47 D77 T78 V79 L105 G106 I124 T164 N263 I265 G296 D297 P312 T313 A314 Q315 A317 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKK 5kmr A 3.00 BS01 FAD A 1 G10 G12 Y13 G14 N37 K38 Y43 T45 T46 H49 D79 T80 V81 L107 G108 I126 N265 I267 G298 D299 P314 T315 A316 Q317 A319 K376 G8 G10 Y11 G12 N35 K36 Y41 T43 T44 H47 D77 T78 V79 L105 G106 I124 N263 I265 G296 D297 P312 T313 A314 Q315 A317 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLK 5kmr A 3.00 BS02 NAD A 1 I116 G162 G164 F165 T166 V197 E198 A199 P205 I232 W258 G260 G261 V262 P313 P314 V350 A351 I114 G160 G162 F163 T164 V195 E196 A197 P203 I230 W256 G258 G259 V260 P311 P312 V348 A349 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLK 5kmr C 3.00 BS01 FAD C 1 G10 G12 Y13 G14 N37 K38 Y43 T45 T46 H49 V81 L107 G108 I126 I267 G298 D299 P314 T315 A316 Q317 A319 G8 G10 Y11 G12 N35 K36 Y41 T43 T44 H47 V79 L102 G103 I121 I262 G293 D294 P309 T310 A311 Q312 A314 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKK 5kmr C 3.00 BS02 NAD C 1 F114 G162 F165 T166 V197 E198 A199 P205 I232 W258 G260 G261 P313 P314 T315 F109 G157 F160 T161 V192 E193 A194 P200 I227 W253 G255 G256 P308 P309 T310 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKK 5kmr D 3.00 BS01 FAD D 1 G10 G12 Y13 G14 N37 K38 Y43 T45 T46 H49 D79 V81 L107 G108 I126 T166 N265 I267 G298 D299 P314 T315 A316 Q317 A319 K376 G8 G10 Y11 G12 N35 K36 Y41 T43 T44 H47 D77 V79 L105 G106 I124 T164 N263 I265 G296 D297 P312 T313 A314 Q315 A317 K374 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKK 5kmr D 3.00 BS02 NAD D 1 F114 I116 G162 G164 F165 T166 E169 V197 E198 A199 P205 P231 I232 W258 G260 G261 V262 P313 P314 V350 F112 I114 G160 G162 F163 T164 E167 V195 E196 A197 P203 P229 I230 W256 G258 G259 V260 P311 P312 V348 F5L3B8 28067272 KPSIVILGAGYGGIVAALGLQKRLNYNEADITLVNKNDYHYITTELHQPAAGTMHHDQARVGIKELIDEKKIKFVKDTVVAIDREQQKVTLQNGELHYDYLVVGLGSEPETFGIEGLREHAFSINSINSVRIIRQHIEYQFAKFAAEPERTDYLTIVVGGAGFTGIEFVGELADRMPELCAEYDVDPKLVRIINVEAAPTVLPGFDPALVNYAMDVLGGKGVEFKIGTPIKRCTPEGVVIEVDGEEEEIKAATVVWTGGVRGNSIVEKSGFETMRGRIKVDPYLRAPGHENIFIVGDCALIINEENNRPYPPTAQIAIQHGENVAANLAALIRGGSMTPFKPHIRGTVASLGRNDAIGIVGGRKVYGHAASWLKKLIDMRYLYLIGGLSLVLKK 5ko3 A 1.95 BS01 ZN A 1 C191 C194 C226 C228 C129 C132 C164 C166 A0A023J538 28079137 DETKALKELYGPVDPTFLHRFYSLKAAVHGWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHKGGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVLQGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQLVEHTTPWLLLSGTPNEKLVTTSTAPDFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSS 5koa B 2.67 BS01 III D 1 W77 G82 V83 D84 L174 Q177 S178 W76 G81 V82 D83 L173 Q176 S177 B7MAM4 QTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDSENGQVPERLDFELACC 5l01 A 1.90 BS01 FE A 1 H272 H277 E317 H161 H166 E206 1.14.16.4 P17752 28041831 TVPWFPKKISDLDHCANRVLMYGGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIK 5l01 A 1.90 BS02 6Z4 A 1 Y235 L236 P238 R257 Y264 T265 P266 E267 P268 H272 A309 Y312 F313 E317 G333 S336 S337 C364 I366 Y124 L125 P127 R146 Y153 T154 P155 E156 P157 H161 A198 Y201 F202 E206 G222 S225 S226 C253 I255 1.14.16.4 P17752 28041831 TVPWFPKKISDLDHCANRVLMYGGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIK 5lc8 A 1.80 BS01 FE2 A 1 H377 H382 H555 N559 I685 H348 H353 H526 N530 I656 1.13.11.12,1.13.11.13 28093240 SIFFSPLKYLGAEQQRSIDASRSLLDNLIPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFANVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIAAGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIALLTRVGLLVDDILKSASNLGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGGARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 5lc8 A 1.80 BS02 ZPE A 1 W105 T109 I113 L182 V185 D190 E373 H377 H382 F415 I416 G419 G420 I423 L424 N607 Y609 L612 I685 W84 T88 I92 L161 V164 D169 E344 H348 H353 F386 I387 G390 G391 I394 L395 N578 Y580 L583 I656 1.13.11.12,1.13.11.13 28093240 SIFFSPLKYLGAEQQRSIDASRSLLDNLIPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFANVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIAAGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIALLTRVGLLVDDILKSASNLGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGGARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 5lmk A 2.40 BS01 6ZK A 1 I10 E12 A31 F80 E81 F82 L83 H84 Q85 K129 Q131 L134 I11 E13 A32 F79 E80 F81 L82 H83 Q84 K128 Q130 L133 2.7.11.22 P24941 28039837 SMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 5lmk B 2.40 BS01 MG B 1 M200 Q203 I206 M26 Q29 I32 P20248 28039837 VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 5lmk C 2.40 BS01 6ZK C 1 I10 E12 A31 F80 E81 F82 L83 H84 Q85 D86 K89 Q131 L134 I11 E13 A32 F81 E82 F83 L84 H85 Q86 D87 K90 Q132 L135 2.7.11.22 P24941 28039837 SMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 5lta A 2.62 BS01 NUC E 1 P151 R152 R153 I179 R180 T195 G197 Q198 R201 T314 G315 E316 E317 Y348 G349 T350 T381 N382 I383 K403 L416 P526 S555 V556 P557 R562 Q627 H688 P689 S690 T708 R714 P91 R92 R93 I119 R120 T135 G137 Q138 R141 T254 G255 E256 E257 Y288 G289 T290 T321 N322 I323 K343 L356 P466 S495 V496 P497 R502 Q567 H628 P629 S630 T648 R654 3.6.4.13 G0RY84 28092261 TTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQA 5lta A 2.62 BS02 ADP A 1 L96 G122 S123 G124 K125 T126 T127 R162 T389 R435 L36 G62 S63 G64 K65 T66 T67 R102 T329 R375 3.6.4.13 G0RY84 28092261 TTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQA 5lta A 2.62 BS03 BEF A 1 T121 K125 E219 A251 R432 R435 T61 K65 E159 A191 R372 R375 3.6.4.13 G0RY84 28092261 TTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQA 5ltj A 1.78 BS01 ADP A 1 L96 G122 S123 G124 K125 T126 T127 R162 T389 R435 T436 L37 G63 S64 G65 K66 T67 T68 R103 T330 R376 T377 G0RY84 28092261 ATTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAMKAS 5ltj A 1.78 BS02 BEF A 1 T121 G122 K125 E219 R432 R435 T62 G63 K66 E160 R373 R376 G0RY84 28092261 ATTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAMKAS 5ltj A 1.78 BS03 MG A 1 T126 E219 T67 E160 G0RY84 28092261 ATTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAMKAS 5ltk A 3.24 BS01 ADP A 1 L96 G122 S123 G124 K125 T126 T127 R162 T389 R435 L36 G62 S63 G64 K65 T66 T67 R102 T329 R375 G0RY84 28092261 TTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAMK 5ltk A 3.24 BS02 BEF A 1 T121 G122 K125 E219 R432 R435 T61 G62 K65 E159 R372 R375 G0RY84 28092261 TTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYPEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAMK 5m2b G 2.70 BS01 MG G 1 T8 Y119 R122 A123 M125 T7 Y118 R121 A122 M124 3.4.25.1 P21243 28098422 GYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ 5m2b J 2.70 BS01 MG J 1 Q118 D120 T124 Q118 D120 T124 3.4.25.1 P22141 28098422 MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF 5m2b K 2.70 BS01 7DX K 1 T1 V31 K33 M45 G47 A49 Q53 G129 S130 T1 V31 K33 M45 G47 A49 Q53 G129 S130 3.4.25.1,3.4.25.1 P30656 28098422 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5m2b K 2.70 BS02 MG K 1 R19 A164 D167 A168 S170 R19 A164 D167 A168 S170 3.4.25.1,3.4.25.1 P30656 28098422 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5m2b L 2.70 BS01 7DX K 1 S124 F125 R137 S124 F125 R137 3.4.25.1,3.4.25.1,3.4.25.1,3.4.25.1,3.4.25.1 P23724 28098422 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYSRRFFPYYVYNIIAGLDEDGKGAVYSFDPVGSYQREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5m2b N 2.70 BS01 MG N 1 R19 I163 D166 S169 R19 I163 D166 S169 3.4.25.1 P38624 28098422 TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL 5m2b V 2.70 BS01 MG L 1 I163 D166 L167 S169 I163 D166 L167 S169 3.4.25.1 P25043 28098422 TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVNICDIQEE 5m2b Y 2.70 BS01 MG I 1 R19 A164 D167 A168 S170 R19 A164 D167 A168 S170 3.4.25.1,3.4.25.1 P30656 28098422 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5m2b Y 2.70 BS02 7DX Y 1 T1 V31 K33 M45 S46 G47 A49 Q53 S130 T1 V31 K33 M45 S46 G47 A49 Q53 S130 3.4.25.1,3.4.25.1 P30656 28098422 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 5m2b Z 2.70 BS01 7DX Y 1 S124 F125 R137 S124 F125 R137 3.4.25.1,3.4.25.1,3.4.25.1,3.4.25.1,3.4.25.1 P23724 28098422 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYSRRFFPYYVYNIIAGLDEDGKGAVYSFDPVGSYQREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5m2b Z 2.70 BS02 MG Z 1 T192 H195 I196 V198 T192 H195 I196 V198 3.4.25.1,3.4.25.1,3.4.25.1,3.4.25.1,3.4.25.1 P23724 28098422 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYSRRFFPYYVYNIIAGLDEDGKGAVYSFDPVGSYQREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5m7n A 2.90 BS01 MG A 1 D9 D10 D53 D9 D10 D53 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRLELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7n A 2.90 BS02 ATP A 1 L142 V143 M149 G173 A174 G175 K176 E177 L178 L319 L355 R356 L136 V137 M143 G167 A168 G169 K170 E171 L172 L308 L344 R345 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRLELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7n A 2.90 BS03 ATP B 1 A331 R370 A320 R359 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRLELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7n B 2.90 BS01 ATP A 1 A331 R370 A319 R358 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRTGELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7n B 2.90 BS02 MG B 1 D9 D10 D53 K105 D9 D10 D53 K99 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRTGELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7n B 2.90 BS03 ATP B 1 L142 V143 M149 G173 A174 G175 K176 E177 L178 F322 L355 R356 R359 L133 V134 M140 G164 A165 G166 K167 E168 L169 F310 L343 R344 R347 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRTGELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7o A 2.20 BS01 MG A 1 D9 D10 E11 D53 K105 D9 D10 E11 D53 K105 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRTGLVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMDGGERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLG 5m7o B 2.20 BS01 MG B 1 D9 D10 E11 D53 K105 D9 D10 E11 D53 K105 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMDGGERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7p A 2.36 BS01 MG A 1 D9 D10 D53 D9 D10 D53 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRLVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMDKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7p A 2.36 BS02 ADP A 1 L142 V143 M149 G173 A174 G175 K176 E177 L178 F322 L355 R356 L134 V135 M141 G165 A166 G167 K168 E169 L170 F310 L343 R344 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRLVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMDKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7p B 2.36 BS01 MG B 1 D9 D10 E11 D53 K105 D9 D10 E11 D53 K100 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRTGDQLELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEITESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5m7p B 2.36 BS02 ADP B 1 E141 L142 V143 M149 G173 A174 G175 K176 E177 L178 F322 L355 R356 E136 L137 V138 M144 G168 A169 G170 K171 E172 L173 F314 L347 R348 C4IRH0 28088479 MAADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLDGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKLKREVSDLRKRTGDQLELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVARAIHAQSSRANGPFVTVNAATITPERMEIELFGTEMERKVGALEEAHGGILYLDEVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFHRLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQLRNNVERLMILTRGDDPDELVTADLLPAEITESDQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSLGV 5miz B BS01 III A 1 C7 G8 S9 V12 L15 C19 G20 C7 G8 S9 V12 L15 C19 G20 P01317 FVNQHLCGSHLVEALYLVCGERGFFYTPKA 5mn9 A 2.05 BS01 III C 1 L8 R42 I44 F45 A46 G47 H68 V70 L71 R72 L73 L8 R42 I44 F45 A46 G47 H68 V70 L71 R72 L73 P62992 28082312 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRL 5mn9 B 2.05 BS01 III C 1 L8 R42 I44 G47 H68 V70 R72 L8 R42 I44 G47 H68 V70 R72 P62992 28082312 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 5mq4 A 2.70 BS01 ZN A 1 C1089 C1090 H1108 C1112 C88 C89 H107 C111 Q9ULU4 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 A 2.70 BS02 ZN A 2 C1078 C1081 C1096 C1100 C77 C80 C95 C99 Q9ULU4 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 B 2.70 BS01 ZN B 1 C1078 C1081 C1096 C1100 C75 C78 C93 C97 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 B 2.70 BS02 ZN B 2 C1089 C1090 H1108 C1112 C86 C87 H105 C109 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 C 2.70 BS01 ZN C 1 C1089 C1090 H1108 C1112 C92 C93 H111 C115 Q9ULU4 MSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 C 2.70 BS02 ZN C 2 C1078 C1081 C1096 C1100 C81 C84 C99 C103 Q9ULU4 MSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 D 2.70 BS01 ZN D 1 C1089 C1090 H1108 C1112 C86 C87 H105 C109 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 D 2.70 BS02 ZN D 2 C1078 C1081 C1096 C1100 C75 C78 C93 C97 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 E 2.70 BS01 ZN E 1 C1089 C1090 H1108 C1112 C86 C87 H105 C109 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 E 2.70 BS02 ZN E 2 C1078 C1081 C1096 C1100 C75 C78 C93 C97 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 F 2.70 BS01 ZN F 1 C1089 C1090 H1108 C1112 C86 C87 H105 C109 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mq4 F 2.70 BS02 ZN F 2 C1078 C1081 C1096 C1100 C75 C78 C93 C97 Q9ULU4 GSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQ 5mrk A 1.90 BS01 SFG A 1 S56 G58 G81 C82 G83 G86 W87 T104 K105 H110 E111 V130 D131 V132 F133 D146 S52 G54 G77 C78 G79 G82 W83 T100 K101 H106 E107 V126 D127 V128 F129 D142 A0A1B0YUR2 GETLGEKWKARLNQMSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGKVIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPMLVQSYGWNIVRLKSGVDVFHMAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMMETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRPVKYEEDVNLGSGTR 5mrk B 1.90 BS01 SFG B 1 S56 G58 G81 C82 G83 G86 W87 T104 K105 H110 E111 V130 D131 V132 F133 D146 S37 G39 G62 C63 G64 G67 W68 T85 K86 H91 E92 V111 D112 V113 F114 D127 A0A1B0YUR2 GETLGEKWKARLNQMSALEFYSYKKSGITEVCRHAVSRGSAKLRWLVERGYLQPYGKVIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPMLVQSYGWNIVRLKSGVDVFHMAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMMETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRPVKYEEDVNLGSGTR 5t0q A 2.15 BS01 III B 1 Q53 W92 G93 D94 Y97 N126 E142 E143 V144 E148 F151 M155 T156 Q9 W48 G49 D50 Y53 N72 E75 E76 V77 E81 F84 M88 T89 Q9FIP9 PQFNEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGENTAEQEHRKRVIRELNSLEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNFN 5t63 A 2.50 BS01 III C 1 Y288 I289 G290 V291 Q292 M293 Q357 Y183 I184 G185 V186 Q187 M188 Q252 P72780 27956128 SESFVAAAVSRSGPAVVRIDTEQGSGFIIDNSGIILTNAHVVDGASKVVVTLRDGRTFDGQVRGTDEVTDLAVVKIEPQGSALPVAPLGTSSNLQVGDWAIAVGNPVGLDNTVTLGIISTLGEFIQTDAAINPGNSGGPLLNARGEVIGINTAITGIGFAIPIDQAKAIQNTLAAGGTVPHPYIGVQMMNITVDQAQQNNRNPNSPFIIPEVDGILVMRVLPGTPAERAGIRRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLLRRRLSLTVQTAQLR 5t9u A 2.30 BS01 7HG A 1 R55 I57 M61 Q63 T73 A101 N102 A103 Q111 F113 L122 H126 R54 I56 M60 Q62 T72 A100 N101 A102 Q110 F112 L121 H125 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL 5t9u B 2.30 BS01 7HG B 1 R55 I57 M61 Q63 G72 T73 A101 N102 A103 Q111 F113 L122 H126 R54 I56 M60 Q62 G71 T72 A100 N101 A102 Q110 F112 L121 H125 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL 5t9u C 2.30 BS01 7HG C 1 R55 I57 M61 Q63 G72 A101 N102 A103 Q111 F113 L122 H126 R54 I56 M60 Q62 G71 A100 N101 A102 Q110 F112 L121 H125 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL 5t9u D 2.30 BS01 7HG D 1 R55 I57 M61 Q63 G72 T73 A101 N102 A103 Q111 F113 L122 H126 R55 I57 M61 Q63 G72 T73 A101 N102 A103 Q111 F113 L122 H126 5.2.1.8 P62937 28075591 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL 5t9w A 2.00 BS01 78E A 1 R55 I57 F60 M61 Q63 A101 N102 A103 Q111 F113 L122 K125 H126 R54 I56 F59 M60 Q62 A100 N101 A102 Q110 F112 L121 K124 H125 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 5t9z A 1.40 BS01 78R A 1 R55 I57 F60 M61 Q63 G72 A101 N102 A103 Q111 F113 H126 R54 I56 F59 M60 Q62 G71 A100 N101 A102 Q110 F112 H125 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL 5ta2 A 1.48 BS01 78X A 1 R55 I57 F60 M61 Q63 G72 T73 A101 N102 A103 Q111 F113 H126 N149 R54 I56 F59 M60 Q62 G71 T72 A100 N101 A102 Q110 F112 H125 N148 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL 5ta4 A 1.50 BS01 838 A 1 R55 I57 F60 M61 Q63 A101 N102 A103 Q111 F113 H126 N149 R54 I56 F59 M60 Q62 A100 N101 A102 Q110 F112 H125 N148 5.2.1.8 P62937 28075591 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 5tc0 A 2.24 BS01 79Y A 1 G596 V601 A617 K619 M650 L671 P672 F673 M674 G677 D678 N728 M730 A740 D741 G19 V24 A40 K42 M53 L74 P75 F76 M77 G80 D81 N131 M133 A143 D144 2.7.10.1 Q12866 28082036 EDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKDFSHPNVMRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFMPVKWIAIETSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESL 5td2 A 2.68 BS01 7AE A 1 E595 G596 V601 A617 K619 M650 L671 P672 F673 M674 K675 G677 D678 N728 M730 A740 D741 E19 G20 V25 A41 K43 M58 L74 P75 F76 M77 K78 G80 D81 N131 M133 A143 D144 2.7.10.1 Q12866 28082036 LEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMAACMKDFSHPNVMRLLGVCIEMSSPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFPVKWIAIESLYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESL 5tdi A 1.40 BS01 7AS A 1 Q19 G23 S24 C25 W26 E59 N60 D61 G64 G65 G66 Y67 M68 A134 L160 N161 H162 A163 Q19 G23 S24 C25 W26 E59 N60 D61 G64 G65 G66 Y67 M68 A134 L160 N161 H162 A163 3.4.22.38 P43235 28049758 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 5tpg A 1.50 BS01 FE A 1 H272 H277 E317 H149 H154 E194 1.14.16.4 P17752 28041831 TVPWFPKKISDLDHCNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIK 5tpg A 1.50 BS02 7H5 A 1 Y235 L236 P238 F241 L242 R257 Y264 T265 P266 E267 P268 H272 A309 Y312 F313 E317 S336 S337 C364 I366 Y112 L113 P115 F118 L119 R134 Y141 T142 P143 E144 P145 H149 A186 Y189 F190 E194 S213 S214 C241 I243 1.14.16.4 P17752 28041831 TVPWFPKKISDLDHCNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIK 5tqh A 2.20 BS01 7J2 A 1 R109 A111 I113 R119 L120 W124 P127 I128 I130 V255 A258 M259 S278 V281 A282 Y285 S287 M291 R107 A109 I111 R117 L118 W122 P125 I126 I128 V250 A253 M254 S267 V270 A271 Y274 S276 M280 1.1.1.42 O75874 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 5tqh A 2.20 BS02 NDP A 1 K72 A74 T75 I76 T77 R82 N96 Q283 L288 H309 G310 T311 V312 T313 R314 H315 T327 N328 K70 A72 T73 I74 T75 R80 N94 Q272 L277 H298 G299 T300 V301 T302 R303 H304 T316 N317 1.1.1.42 O75874 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 5tqh B 2.20 BS01 7J2 B 1 R109 E110 A111 I113 R119 L120 W124 I128 I130 V255 M259 W267 Y272 Q277 S278 V281 Y285 S287 M291 R107 E108 A109 I111 R117 L118 W122 I126 I128 V250 M254 W262 Y267 Q272 S273 V276 Y280 S282 M286 1.1.1.42 O75874 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 5tqh B 2.20 BS02 NDP B 1 K72 A74 T75 T77 R82 N96 Q283 L288 G289 H309 G310 T311 V312 T313 R314 H315 N328 D375 K70 A72 T73 T75 R80 N94 Q278 L283 G284 H304 G305 T306 V307 T308 R309 H310 N323 D370 1.1.1.42 O75874 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 5tqh C 2.20 BS01 7J2 C 1 R109 A111 I113 R119 L120 W124 I128 I130 V255 M259 W267 Q277 S278 V281 Y285 S287 M291 R107 A109 I111 R117 L118 W122 I126 I128 V249 M253 W261 Q271 S272 V275 Y279 S281 M285 1.1.1.42 O75874 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 5tqh C 2.20 BS02 NDP C 1 K72 A74 T75 I76 T77 R82 N96 L288 E306 H309 G310 T311 V312 T313 R314 H315 T327 N328 K70 A72 T73 I74 T75 R80 N94 L282 E300 H303 G304 T305 V306 T307 R308 H309 T321 N322 1.1.1.42 O75874 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 5tqh D 2.20 BS01 7J2 D 1 R109 A111 I113 R119 L120 W124 P127 I128 I130 M259 W267 V281 A282 Y285 S287 M291 R106 A108 I110 R116 L117 W121 P124 I125 I127 M256 W264 V271 A272 Y275 S277 M281 1.1.1.42 O75874 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 5tqh D 2.20 BS02 NDP D 1 K72 A74 T75 I76 T77 R82 N96 L288 G289 E306 H309 G310 T311 V312 T313 R314 H315 T327 N328 K69 A71 T72 I73 T74 R79 N93 L278 G279 E296 H299 G300 T301 V302 T303 R304 H305 T317 N318 1.1.1.42 O75874 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 5ttk A 2.51 BS01 FAD A 1 V59 G60 G62 F63 A64 E83 A84 R85 G89 G90 R91 T92 F104 G105 G106 W108 V279 T307 V308 P309 I316 W417 F422 A426 W427 G452 A453 A461 N462 I463 A466 V9 G10 G12 F13 A14 E33 A34 R35 G39 G40 R41 T42 F54 G55 G56 W58 V229 T257 V258 P259 I266 W367 F372 A376 W377 G402 A403 A411 N412 I413 A416 F8G0P2 27933790 GFDYDVVVVGGGFAGATAARECGLQGYRTLLLEARSRLGGRTFTSRFAGQEIEFGGAWVHWLQPHVWAEMQRYGLGVVEDPLTNLDKTLIMYNDGSVESISPDEFGKNIRIAFEKLCHDAWEVFPRPHEPMFTERARELDKSSVLDRIKTLGLSRLQQAQINSYMALYAGETTDKFGLPGVLKLFACGGWNYDAFMDTETHYRIQGGTIGLINAMLTDSGAEVRMSVPVTAVEQVNGGVKIKTDDDEIITAGVVVMTVPLNTYKHIGFTPALSKGKQRFIKEGQLSKGAKLYVHVKQNLGRVFAFADEQQPLNWVQTHDYSDELGTILSITIARKETIDVNDRDAVTREVQKMFPGVEVLGTAAYDWTADPFSLGAWAAYGVGQLSRLKDLQAAEGRILFAGAETSNGWHANIDGAVESGLRAGREVKQLLS 5ttk B 2.51 BS01 FAD B 1 V59 G60 G62 F63 A64 E83 A84 R85 G90 R91 T92 F104 G105 G106 A107 W108 P278 V279 T307 V308 P309 W417 F422 A426 W427 G452 A453 A461 N462 I463 A466 V9 G10 G12 F13 A14 E33 A34 R35 G40 R41 T42 F54 G55 G56 A57 W58 P228 V229 T257 V258 P259 W367 F372 A376 W377 G402 A403 A411 N412 I413 A416 F8G0P2 27933790 GFDYDVVVVGGGFAGATAARECGLQGYRTLLLEARSRLGGRTFTSRFAGQEIEFGGAWVHWLQPHVWAEMQRYGLGVVEDPLTNLDKTLIMYNDGSVESISPDEFGKNIRIAFEKLCHDAWEVFPRPHEPMFTERARELDKSSVLDRIKTLGLSRLQQAQINSYMALYAGETTDKFGLPGVLKLFACGGWNYDAFMDTETHYRIQGGTIGLINAMLTDSGAEVRMSVPVTAVEQVNGGVKIKTDDDEIITAGVVVMTVPLNTYKHIGFTPALSKGKQRFIKEGQLSKGAKLYVHVKQNLGRVFAFADEQQPLNWVQTHDYSDELGTILSITIARKETIDVNDRDAVTREVQKMFPGVEVLGTAAYDWTADPFSLGAWAAYGVGQLSRLKDLQAAEGRILFAGAETSNGWHANIDGAVESGLRAGREVKQLLS 5ttk C 2.51 BS01 FAD C 1 V59 G60 G61 G62 F63 A64 E83 A84 R85 G90 R91 T92 F104 G105 G106 A107 W108 V279 T307 V308 P309 I316 W417 F422 A426 W427 G452 A453 A461 N462 I463 A466 V9 G10 G11 G12 F13 A14 E33 A34 R35 G40 R41 T42 F54 G55 G56 A57 W58 V229 T257 V258 P259 I266 W367 F372 A376 W377 G402 A403 A411 N412 I413 A416 F8G0P2 27933790 GFDYDVVVVGGGFAGATAARECGLQGYRTLLLEARSRLGGRTFTSRFAGQEIEFGGAWVHWLQPHVWAEMQRYGLGVVEDPLTNLDKTLIMYNDGSVESISPDEFGKNIRIAFEKLCHDAWEVFPRPHEPMFTERARELDKSSVLDRIKTLGLSRLQQAQINSYMALYAGETTDKFGLPGVLKLFACGGWNYDAFMDTETHYRIQGGTIGLINAMLTDSGAEVRMSVPVTAVEQVNGGVKIKTDDDEIITAGVVVMTVPLNTYKHIGFTPALSKGKQRFIKEGQLSKGAKLYVHVKQNLGRVFAFADEQQPLNWVQTHDYSDELGTILSITIARKETIDVNDRDAVTREVQKMFPGVEVLGTAAYDWTADPFSLGAWAAYGVGQLSRLKDLQAAEGRILFAGAETSNGWHANIDGAVESGLRAGREVKQLLSLEH 5ttk D 2.51 BS01 FAD D 1 V59 G60 G62 A64 E83 A84 R85 G89 G90 R91 F104 G105 G106 W108 P278 V279 T307 V308 P309 F422 A426 W427 G452 A453 A461 N462 I463 A466 V9 G10 G12 A14 E33 A34 R35 G39 G40 R41 F54 G55 G56 W58 P228 V229 T257 V258 P259 F372 A376 W377 G402 A403 A411 N412 I413 A416 F8G0P2 27933790 GFDYDVVVVGGGFAGATAARECGLQGYRTLLLEARSRLGGRTFTSRFAGQEIEFGGAWVHWLQPHVWAEMQRYGLGVVEDPLTNLDKTLIMYNDGSVESISPDEFGKNIRIAFEKLCHDAWEVFPRPHEPMFTERARELDKSSVLDRIKTLGLSRLQQAQINSYMALYAGETTDKFGLPGVLKLFACGGWNYDAFMDTETHYRIQGGTIGLINAMLTDSGAEVRMSVPVTAVEQVNGGVKIKTDDDEIITAGVVVMTVPLNTYKHIGFTPALSKGKQRFIKEGQLSKGAKLYVHVKQNLGRVFAFADEQQPLNWVQTHDYSDELGTILSITIARKETIDVNDRDAVTREVQKMFPGVEVLGTAAYDWTADPFSLGAWAAYGVGQLSRLKDLQAAEGRILFAGAETSNGWHANIDGAVESGLRAGREVKQLLSLEH 5twa A 1.85 BS01 III D 1 T91 G93 I94 F103 G106 W108 E118 E121 V122 R125 T126 H132 G134 R135 A138 F142 Y190 T193 L194 T54 G56 I57 F66 G69 W71 E81 E84 V85 R88 T89 H95 G97 R98 A101 F105 Y153 T156 L157 Q967D2 28079890 GPLGSSRLYLQNTAVMEELYRRNLEYWREDGLSEEERRTAADAAERMTAVIAGTPGIAVERNVRDFRRGGWDVTPDNVESEFREVERRTFSDGVHWGRVIAFLAFSMSFAAYVNSRGIDGGAYSVFNWTLRVLNDSLADFIQRENGWRGFIVYADTLLRAQ 5twa B 1.85 BS01 III C 1 T91 G93 I94 F103 W108 E118 E121 V122 R125 T126 H132 G134 R135 A138 F142 Y190 T193 L194 A197 T52 G54 I55 F64 W69 E79 E82 V83 R86 T87 H93 G95 R96 A99 F103 Y151 T154 L155 A158 Q967D2 28079890 GPLGSSRLYLQNTAVMEELYRRNLSEYWRLSEEERRTAADAAERMTAVIAGTPGIAVERNVRDFRRGGWDVTPDNVESEFREVERRTFSDGVHWGRVIAFLAFSMSFAAYVNSRGIDGGAYSVFNWTLRVLNDSLADFIQRENGWRGFIVYADTLLRA 5twt A 1.30 BS01 HEM A 1 R31 A34 S35 L37 R38 F41 S71 P137 P138 P139 L146 F150 L160 L163 S164 A166 H167 I169 G170 Q171 A172 Q173 N176 L210 L233 S235 M267 R31 A34 S35 L37 R38 F41 S71 P137 P138 P139 L146 F150 L160 L163 S164 A166 H167 I169 G170 Q171 A172 Q173 N176 L210 L233 S235 M267 1.11.1.7 27879392 QLSSTFYDTSCPNALSTIRSAVNAAVAQENRMGASLLRLHFHDCFVQGCDASVLLNDTNGGEQNALPNAGSLRGFGVIDNIKAQVEALCPQTVSCADILAVAARDSVVALGGPSWTVPLGRRDSTNSSAALANSDLPPPQFNLSQLITAFGNKNLDPTDLVALSGAHTIGQAQCLNFRAHITEPNINPTFAASLRANCPATGGDTNLAPLDVTTPNTFDNAYYTNLLNQRGLLHSDQELFNNASTDSTVRNFASNAAAFTTAFTTAMIKMGNLQPLTGTQGQIRRNCWRVN 5twt A 1.30 BS02 CA A 1 T168 D211 T214 T217 D219 T168 D211 T214 T217 D219 1.11.1.7 27879392 QLSSTFYDTSCPNALSTIRSAVNAAVAQENRMGASLLRLHFHDCFVQGCDASVLLNDTNGGEQNALPNAGSLRGFGVIDNIKAQVEALCPQTVSCADILAVAARDSVVALGGPSWTVPLGRRDSTNSSAALANSDLPPPQFNLSQLITAFGNKNLDPTDLVALSGAHTIGQAQCLNFRAHITEPNINPTFAASLRANCPATGGDTNLAPLDVTTPNTFDNAYYTNLLNQRGLLHSDQELFNNASTDSTVRNFASNAAAFTTAFTTAMIKMGNLQPLTGTQGQIRRNCWRVN 5twt A 1.30 BS03 CA A 2 D43 V46 Q47 G48 D50 S52 D43 V46 Q47 G48 D50 S52 1.11.1.7 27879392 QLSSTFYDTSCPNALSTIRSAVNAAVAQENRMGASLLRLHFHDCFVQGCDASVLLNDTNGGEQNALPNAGSLRGFGVIDNIKAQVEALCPQTVSCADILAVAARDSVVALGGPSWTVPLGRRDSTNSSAALANSDLPPPQFNLSQLITAFGNKNLDPTDLVALSGAHTIGQAQCLNFRAHITEPNINPTFAASLRANCPATGGDTNLAPLDVTTPNTFDNAYYTNLLNQRGLLHSDQELFNNASTDSTVRNFASNAAAFTTAFTTAMIKMGNLQPLTGTQGQIRRNCWRVN 5twv A 6.30 BS01 ATP A 1 N48 I49 R50 N17 I18 R19 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv A 6.30 BS02 ATP G 1 I182 F183 K185 L205 F333 G334 I151 F152 K154 L174 F302 G303 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv C 6.30 BS01 ATP A 1 I182 F183 K185 L205 F333 G334 I151 F152 K154 L174 F302 G303 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv C 6.30 BS02 ATP C 1 N48 I49 R50 N17 I18 R19 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv E 6.30 BS01 ATP C 1 I182 F183 K185 L205 F333 G334 I151 F152 K154 L174 F302 G303 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv E 6.30 BS02 ATP E 1 N48 I49 R50 N17 I18 R19 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv G 6.30 BS01 ATP E 1 I182 F183 K185 L205 F333 G334 I151 F152 K154 L174 F302 G303 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5twv G 6.30 BS02 ATP G 1 N48 I49 R50 N17 I18 R19 28092267 RARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITPRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLL 5u2i B 1.40 BS01 MG B 1 R5 K33 E78 R5 K33 E78 MSNERTFIALKPDAVQRGLVGTIIARFEQKGFKLVALKLITPSADLAKKHYAEHDGKPFFNGLVEFLTSGPVAAMVWEGKGVVAAARKMIGATKPLESAPGTIRGDFAIDVGRNIIHGSDAVETAQREIALWFQDSELNEWTPTQNKWIYE 5u2i D 1.40 BS01 MG D 1 D55 G56 D55 G56 MSNERTFIALKPDAVQRGLVGTIIARFEQKGFKLVALKLITPSADLAKKHYAEHDGKPFFNGLVEFLTSGPVAAMVWEGKGVVAAARKMIGATKPLESAPGTIRGDFAIDVGRNIIHGSDAVETAQREIALWFQDSELNEWTPTQNKWIYE 5u30 A 2.92 BS01 NUC B 1 V3 K4 S5 K9 R11 R227 W234 V238 P279 R294 K323 Q326 R327 H336 D337 K370 A374 K375 A378 T379 T381 H388 P389 W391 R415 S442 M443 S444 Q446 Y466 Q482 R484 R485 H490 H492 R494 Y501 N503 R597 F600 H614 S617 Q618 L619 K621 K629 D630 I634 R653 R657 R665 W723 R724 G727 V730 R731 R734 V737 R738 S739 R742 P743 K744 I745 R746 G747 V753 G754 G755 N756 Q760 Y763 L764 Q767 K769 K772 S773 W774 S775 F776 G782 Q783 V784 I785 R792 F793 A794 I795 T796 L797 H800 H803 D807 K810 K811 D814 R815 E819 V824 Y825 K832 W835 Y839 F855 N856 N857 P861 N864 N865 M868 N881 Q882 R904 R914 A917 R918 D949 F971 H972 Q973 H975 L978 Q982 V4 K5 S6 K10 R12 R226 W233 V237 P278 R293 K322 Q325 R326 H335 D336 K369 A373 K374 A377 T378 T380 H387 P388 W390 R414 S441 M442 S443 Q445 Y465 Q481 R483 R484 H489 H491 R493 Y498 N500 R594 F597 H611 S614 Q615 L616 K618 K626 D627 I631 R650 R654 R662 W720 R721 G724 V727 R728 R731 V734 R735 S736 R739 P740 K741 I742 R743 G744 V750 G751 G752 N753 Q757 Y760 L761 Q764 K766 K769 S770 W771 S772 F773 G779 Q780 V781 I782 R789 F790 A791 I792 T793 L794 H797 H800 D804 K807 K808 D811 R812 E816 V821 Y822 K829 W832 Y836 F852 N853 N854 P858 N861 N862 M865 N878 Q879 R901 R911 A914 R915 D946 F968 H969 Q970 H972 L975 Q979 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u30 A 2.92 BS02 NUC C 1 V3 S5 Q109 A117 Q118 Q119 A142 G143 N144 K145 Q222 E226 S230 S233 W234 R237 G280 L281 E282 S283 K284 E285 A288 H289 T292 R294 A295 R297 T330 R331 R332 F333 G334 S335 K396 N400 G478 S505 R507 L573 R574 R643 R646 R766 V784 R786 A787 E788 K789 G790 S791 R792 F793 R798 K805 L850 E852 Y853 F855 R859 P860 P861 S862 Q866 M868 W870 S871 R873 G874 A895 A896 F897 S898 S899 R900 R911 R913 W930 K934 G955 E956 W1097 V4 S6 Q110 A118 Q119 Q120 A143 G144 N145 K146 Q221 E225 S229 S232 W233 R236 G279 L280 E281 S282 K283 E284 A287 H288 T291 R293 A294 R296 T329 R330 R331 F332 G333 S334 K395 N399 G477 S502 R504 L570 R571 R640 R643 R763 V781 R783 A784 E785 K786 G787 S788 R789 F790 R795 K802 L847 E849 Y850 F852 R856 P857 P858 S859 Q863 M865 W867 S868 R870 G871 A892 A893 F894 S895 S896 R897 R908 R910 W927 K931 G952 E953 W1068 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u30 A 2.92 BS03 NUC D 1 Q119 R122 S126 A133 V134 G135 G136 L137 A140 A142 G143 N144 R147 R150 R208 G210 Q211 A212 V213 T215 R218 Q403 Q120 R123 S127 A134 V135 G136 G137 L138 A141 A143 G144 N145 R148 R151 R207 G209 Q210 A211 V212 T214 R217 Q402 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u31 A 2.89 BS01 NUC B 1 V3 K4 S5 K9 R11 W234 V238 P279 R294 K323 Q326 R327 H336 D337 K370 A374 K375 A378 T379 T381 H388 P389 W391 R415 S442 M443 S444 Q446 Y466 K480 Q482 R484 R485 H490 H492 Y501 N503 K595 R597 F600 H614 S617 Q618 L619 K621 K629 D630 I634 R653 R657 R665 W723 R724 G727 V730 R731 R734 V737 R738 S739 R742 P743 K744 I745 R746 G747 Y748 V753 G754 G755 Q760 Y763 L764 Q767 K769 L771 K772 S773 W774 S775 F776 G782 Q783 V784 I785 R792 F793 A794 I795 T796 L797 H800 H803 D807 K810 K811 D814 R815 E819 V824 Y825 K832 W835 K838 Y839 F855 N856 N857 P861 N864 N865 M868 N881 R904 R914 P916 A917 R918 D949 F971 H972 Q973 H975 L978 Q982 V4 K5 S6 K10 R12 W233 V237 P278 R293 K322 Q325 R326 H335 D336 K369 A373 K374 A377 T378 T380 H387 P388 W390 R414 S441 M442 S443 Q445 Y465 K479 Q481 R483 R484 H489 H491 Y498 N500 K592 R594 F597 H611 S614 Q615 L616 K618 K626 D627 I631 R650 R654 R662 W720 R721 G724 V727 R728 R731 V734 R735 S736 R739 P740 K741 I742 R743 G744 Y745 V750 G751 G752 Q757 Y760 L761 Q764 K766 L768 K769 S770 W771 S772 F773 G779 Q780 V781 I782 R789 F790 A791 I792 T793 L794 H797 H800 D804 K807 K808 D811 R812 E816 V821 Y822 K829 W832 K835 Y836 F852 N853 N854 P858 N861 N862 M865 N878 R901 R911 P913 A914 R915 D946 F968 H969 Q970 H972 L975 Q979 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u31 A 2.89 BS02 NUC C 1 V3 S5 Q109 A117 Q118 Q119 R122 A142 G143 N144 K145 Q222 E226 S230 S233 W234 R237 G280 L281 E282 K284 E285 H289 T292 R294 A295 R297 T330 R331 F333 G334 S335 K396 N400 G478 S505 R507 R646 V784 R786 A787 E788 K789 G790 S791 R792 F793 R798 K805 F855 P860 P861 S862 M868 S871 R873 G874 Q877 V4 S6 Q110 A118 Q119 Q120 R123 A143 G144 N145 K146 Q221 E225 S229 S232 W233 R236 G279 L280 E281 K283 E284 H288 T291 R293 A294 R296 T329 R330 F332 G333 S334 K395 N399 G477 S502 R504 R643 V781 R783 A784 E785 K786 G787 S788 R789 F790 R795 K802 F852 P857 P858 S859 M865 S868 R870 G871 Q874 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u31 A 2.89 BS03 NUC D 1 Q119 R122 S126 A133 V134 G135 G136 L137 A140 A142 G143 N144 R147 R150 R208 G210 Q211 A212 V213 R218 Q403 Q120 R123 S127 A134 V135 G136 G137 L138 A141 A143 G144 N145 R148 R151 R207 G209 Q210 A211 V212 R217 Q402 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u31 A 2.89 BS04 NUC E 1 R331 R332 L573 R574 L850 E852 Y853 R859 E863 Q866 W870 A895 A896 F897 S898 S899 R900 I910 R911 R913 W930 G955 E956 Q1093 W1097 N1101 R330 R331 L570 R571 L847 E849 Y850 R856 E860 Q863 W867 A892 A893 F894 S895 S896 R897 I907 R908 R910 W927 G952 E953 Q1064 W1068 N1072 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u33 A 3.75 BS01 NUC B 1 V3 K4 S5 K9 R11 R227 W234 V238 P279 R294 K323 Q326 R327 H336 D337 K370 A374 K375 T379 T381 H388 P389 W391 R415 S442 M443 S444 Q446 Y466 K480 Q482 R484 R485 H490 H492 Y501 N503 S594 K595 R597 F600 H614 E615 R616 S617 Q618 L619 K621 K629 D630 I634 R653 R657 R665 W723 R724 G727 V730 R731 R734 V737 R738 S739 R742 P743 K744 I745 R746 G747 Y748 V752 V753 G754 G755 Q760 Y763 L764 Q767 K769 L771 K772 S773 W774 S775 F776 G782 Q783 V784 I785 R792 F793 A794 I795 T796 L797 H800 H803 D807 K810 K811 D814 R815 E819 V824 Y825 K832 W835 K838 Y839 F855 N856 N857 P861 N864 N865 M868 N881 Q882 R904 R914 P916 A917 R918 D949 H972 Q973 H975 L978 Q982 V4 K5 S6 K10 R12 R226 W233 V237 P278 R293 K322 Q325 R326 H335 D336 K369 A373 K374 T378 T380 H387 P388 W390 R414 S441 M442 S443 Q445 Y465 K479 Q481 R483 R484 H489 H491 Y498 N500 S591 K592 R594 F597 H611 E612 R613 S614 Q615 L616 K618 K626 D627 I631 R650 R654 R662 W720 R721 G724 V727 R728 R731 V734 R735 S736 R739 P740 K741 I742 R743 G744 Y745 V749 V750 G751 G752 Q757 Y760 L761 Q764 K766 L768 K769 S770 W771 S772 F773 G779 Q780 V781 I782 R789 F790 A791 I792 T793 L794 H797 H800 D804 K807 K808 D811 R812 E816 V821 Y822 K829 W832 K835 Y836 F852 N853 N854 P858 N861 N862 M865 N878 Q879 R901 R911 P913 A914 R915 D946 H969 Q970 H972 L975 Q979 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u33 A 3.75 BS02 NUC C 1 V3 S5 A117 Q118 A142 G143 N144 K145 K209 Q222 E226 S230 S233 W234 R237 G280 L281 E282 S283 K284 E285 A288 H289 T292 R294 R297 T330 R331 F333 G334 S335 R393 D395 K396 N400 G478 S505 R507 R646 V784 R786 A787 E788 K789 S791 R792 F793 R798 K805 F855 P860 P861 S862 M868 S871 R873 G874 V4 S6 A118 Q119 A143 G144 N145 K146 K208 Q221 E225 S229 S232 W233 R236 G279 L280 E281 S282 K283 E284 A287 H288 T291 R293 R296 T329 R330 F332 G333 S334 R392 D394 K395 N399 G477 S502 R504 R643 V781 R783 A784 E785 K786 S788 R789 F790 R795 K802 F852 P857 P858 S859 M865 S868 R870 G871 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u33 A 3.75 BS03 NUC D 1 Q119 R122 K123 S126 V134 G135 G136 L137 A140 A142 G143 N144 P146 R147 R150 K165 R169 R208 Q211 A212 V213 T215 R218 R332 Q403 G572 L573 R574 L850 Y853 Q866 W870 A895 F897 S899 R900 R911 G955 E956 Q120 R123 K124 S127 V135 G136 G137 L138 A141 A143 G144 N145 P147 R148 R151 K164 R168 R207 Q210 A211 V212 T214 R217 R331 Q402 G569 L570 R571 L847 Y850 Q863 W867 A892 F894 S896 R897 R908 G952 E953 3.1.-.- T0D7A2 27984729 SMAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPNGDGEQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVGGLGIAKAGNKPRWVRMREAGEWEEEKEKAETRKSADRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASPGLESKEQTAHYVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHRRRRDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVALGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPARCTQEHNPEPFPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHAALNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYERERGREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u34 A 3.26 BS01 NUC B 1 V3 K4 S5 K9 R11 R227 W234 T379 T381 H388 W391 R415 S442 M443 S444 Q446 Q482 Y501 N503 P599 F600 H614 S617 Q618 L619 R632 I634 W723 G727 V730 R731 R734 V737 R738 S739 R742 P743 K744 I745 R746 G747 Y748 V753 G754 G755 N756 Q760 Y763 L764 Q767 L771 W774 S775 R792 F793 A794 I795 T796 L797 H800 H803 D807 K810 K811 D814 R815 E819 V824 Y825 W835 K838 Y839 N881 Q882 Q884 R904 R914 P916 D949 H972 Q973 H975 L978 Q982 V3 K4 S5 K9 R11 R174 W181 T314 T316 H323 W326 R350 S377 M378 S379 Q381 Q417 Y421 N423 P515 F516 H530 S533 Q534 L535 R548 I550 W622 G626 V629 R630 R633 V636 R637 S638 R641 P642 K643 I644 R645 G646 Y647 V652 G653 G654 N655 Q659 Y662 L663 Q666 L670 W673 S674 R677 F678 A679 I680 T681 L682 H685 H688 D692 K695 K696 D699 R700 E704 V709 Y710 W716 K719 Y720 N762 Q763 Q765 R785 R795 P797 D818 H841 Q842 H844 L847 Q851 3.1.-.- T0D7A2 27984729 MAVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRCDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLARTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEASVTGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVDLGLRTSASISVFRVARKDELKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIANHMTPDWREAFENELQKLKSDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALKGKWVAKYPPCQLILLAELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVPPWWLNKFVVEHTLDACPLRADDLIPTGEGEIFVSPFSAEEGDFHQIHADLNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYEREEADEAREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRS 5u35 A 1.80 BS01 MXE A 1 E3 E4 E6 E7 GSHMTEEEVRKIMEKLKKAFKQGNPEQIVSLLSPDVKVDVGNQSFSGSEEAEKAARKLMKFVDRVEVRDVRVFENAVMIAVEFEVNGQRYKMIFTFYVENGKVSMVSIYISPTMKKLMKQILNYG 5u35 A 1.80 BS02 MXE A 2 F58 L114 Q117 F61 L117 Q120 GSHMTEEEVRKIMEKLKKAFKQGNPEQIVSLLSPDVKVDVGNQSFSGSEEAEKAARKLMKFVDRVEVRDVRVFENAVMIAVEFEVNGQRYKMIFTFYVENGKVSMVSIYISPTMKKLMKQILNYG 5u35 A 1.80 BS03 MXE A 3 D60 E81 D63 E84 GSHMTEEEVRKIMEKLKKAFKQGNPEQIVSLLSPDVKVDVGNQSFSGSEEAEKAARKLMKFVDRVEVRDVRVFENAVMIAVEFEVNGQRYKMIFTFYVENGKVSMVSIYISPTMKKLMKQILNYG 5u35 B 1.80 BS01 MXE B 1 F17 K18 V62 E63 V64 F20 K21 V65 E66 V67 GSHMTEEEVRKIMEKLKKAFKQGNPEQIVSLLSPDVKVDVGNQSFSGSEEAEKAARKLMKFVDRVEVRDVRVFENAVMIAVEFEVNGQRYKMIFTFYVENGKVSMVSIYISPTMKKLMKQI 5u6p A 3.51 BS01 CMP A 1 M530 F538 G539 E540 I541 C542 R549 T550 A551 R590 M426 F434 G435 E436 I437 C438 R445 T446 A447 R486 O60741 28086084 MQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGRALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKD 5u6p B 3.51 BS01 CMP B 1 M530 F538 G539 E540 I541 C542 R549 T550 A551 R590 M426 F434 G435 E436 I437 C438 R445 T446 A447 R486 O60741 28086084 MQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGRALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKD 5u6p C 3.51 BS01 CMP C 1 M530 F538 G539 E540 I541 C542 R549 T550 A551 R590 M426 F434 G435 E436 I437 C438 R445 T446 A447 R486 O60741 28086084 MQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGRALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKD 5u6p D 3.51 BS01 CMP D 1 M530 F538 G539 E540 I541 C542 R549 T550 A551 R590 M426 F434 G435 E436 I437 C438 R445 T446 A447 R486 O60741 28086084 MQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGRALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKD 5u8l A 1.60 BS01 O44 A 1 L718 G719 S720 G721 A722 F723 G724 V726 A743 K745 M790 Q791 L792 M793 G796 L844 T854 F856 L17 G18 S19 G20 A21 F22 G23 V25 A42 K44 M89 Q90 L91 M92 G95 L143 T153 F155 2.7.10.1 P00533 28051857 ALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLP 5u8o A 2.40 BS01 ZN A 1 H94 H96 H205 D224 H97 H99 H199 D218 A0A0H3KRR5 HHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAAGGAAAADHFARHGLTDAASLEKLRNYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRRELDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIA 5u8o A 2.40 BS02 ZN A 2 D98 H99 D224 H269 D101 H102 D218 H263 A0A0H3KRR5 HHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAAGGAAAADHFARHGLTDAASLEKLRNYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRRELDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIA 5u8o A 2.40 BS03 CA A 1 L123 G124 E208 L126 G127 E202 A0A0H3KRR5 HHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAAGGAAAADHFARHGLTDAASLEKLRNYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRRELDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIA 5u8o B 2.40 BS01 CA A 1 L123 G124 E208 L127 G128 E209 A0A0H3KRR5 HHHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAASNAGGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRRELDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIAR 5u8o B 2.40 BS02 ZN B 1 H94 H96 H205 D224 H98 H100 H206 D225 A0A0H3KRR5 HHHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAASNAGGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRRELDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIAR 5u8o B 2.40 BS03 ZN B 2 D98 H99 D224 H269 D102 H103 D225 H270 A0A0H3KRR5 HHHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAASNAGGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRRELDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIAR 5u8o C 2.40 BS01 ZN C 1 H94 H96 H205 D224 H97 H99 H201 D220 A0A0H3KRR5 HHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAAGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIA 5u8o C 2.40 BS02 ZN C 2 D98 H99 D224 H269 D101 H102 D220 H265 A0A0H3KRR5 HHHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAAGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRRHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIA 5u8o D 2.40 BS01 ZN D 1 H94 H96 H205 D224 H96 H98 H203 D222 A0A0H3KRR5 HHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAANAGGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRLDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIAR 5u8o D 2.40 BS02 ZN D 2 D98 H99 D224 H269 D100 H101 D222 H267 A0A0H3KRR5 HHMNALEHQLDYPFADTLPAAGDTFEVAPGVRWLRMPLPFSLDHINLWLLRDEIDGQAGWTVVDCGIASDAIRTHWEQIFDAHLDGLPVLRVIVTHCHPDHFGLANWLCEGGDKRRWNVRLWMTLGEYMFGCLMAANAGGAAAADHFARHGLTDAASLEKLRNRRSYYSDLVPAVPPRYRRLRDGDAVTIGTRTWRVVTGYGHSPEHCALHSEADGVLISGDMVLPRISTNVSVFDLEPEANPLALYLQSLGRYETMAPDTLVLPSHGKPFRGVRTRIAQLRAHHDARLDEVRVACAEQPMSAADIVPIMFRLDIHQMTFALGEAIAHLNLLWLAGELVREQGDDGVLRFRIAR 5u8s 2 6.10 BS01 NUC F 1 S579 R581 K633 A634 S366 R368 K420 A421 3.6.4.12 P29469 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 5u8s 2 6.10 BS02 ATP 2 1 I505 G507 D544 P545 G546 T547 A548 K549 S550 Q551 E608 L695 I292 G294 D331 P332 G333 T334 A335 K336 S337 Q338 E395 L482 3.6.4.12 P29469 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 5u8s 2 6.10 BS03 ATP 5 1 H621 E625 R676 V807 R808 H408 E412 R463 V545 R546 3.6.4.12 P29469 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 5u8s 3 6.10 BS01 NUC F 1 S438 A444 A445 T447 T448 K499 S371 A377 A378 T380 T381 K432 3.6.4.12 P24279 PDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNLIGFKTLILGNTVYPLHAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 5u8s 3 6.10 BS02 ATP 3 1 S370 I371 Y372 P411 S412 T413 A414 K415 S416 Q417 N517 S303 I304 Y305 P344 S345 T346 A347 K348 S349 Q350 N450 3.6.4.12 P24279 PDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNLIGFKTLILGNTVYPLHAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 5u8s 4 6.10 BS01 NUC G 1 Q450 R451 Q266 R267 3.6.4.12 P30665 LRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDERDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKVSVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVIVLGEGVRRSVRL 5u8s 5 6.10 BS01 NUC F 1 V453 R455 R460 K506 A507 V360 R362 R367 K413 A414 3.6.4.12 P29496 NTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISINSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNTGNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNSGVAIRTPYIKILGIQSDVETVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS 5u8s 5 6.10 BS02 ATP 3 1 E498 Q499 I650 R651 E405 Q406 I554 R555 3.6.4.12 P29496 NTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISINSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNTGNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNSGVAIRTPYIKILGIQSDVETVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS 5u8s 5 6.10 BS03 ATP 5 1 S377 I378 F379 P418 G419 T420 A421 K422 S423 Q424 N524 S284 I285 F286 P325 G326 T327 A328 K329 S330 Q331 N431 3.6.4.12 P29496 NTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISINSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNTGNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNSGVAIRTPYIKILGIQSDVETVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS 5u8s 6 6.10 BS01 NUC F 1 A611 K665 A666 A375 K429 A430 3.6.4.12 P53091 VDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKGLRRVVRKYAPERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTGVRDLTYKISFLACHVISIGSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDV 5u8s 6 6.10 BS02 ATP 2 1 H653 E657 P704 R708 R798 H417 E421 P468 R472 R562 3.6.4.12 P53091 VDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKGLRRVVRKYAPERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTGVRDLTYKISFLACHVISIGSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDV 5uao A 1.88 BS01 FAD A 1 G36 G37 G38 T39 A40 S62 I65 I67 I68 V70 G71 E72 A73 A199 T200 V201 C231 T232 G233 L237 W285 V326 N346 F350 P353 S356 G358 L359 G16 G17 G18 T19 A20 S42 I45 I47 I48 V50 G51 E52 A53 A179 T180 V181 C211 T212 G213 L217 W265 V306 N326 F330 P333 S336 G338 L339 W2EQU4 28032983 PADDDPGAIRTVGVIGGGTAGYLTALALKAKRPWLDVALVESADIPIIGVGEATVSYMVMFLHHYLGIDPAEFYQHVRPTWKLGIRFEWGSRPEGFVAPFDWGTGSVGLVGSLRETGNVNEATLQAMLMTEDRVPVYRGEGGHVSLMKYLPFAYHMDNARLVRYLTELAARRGVRHVDATVAEVRLDGPDHVGGLITTDGRRLHYDFYVDCTGFRSLLLEKALGIPFESYASSLFTDAAVTGTLAHGGHLKPYTTATTMNAGWCWTIPTPESDHLGYVFSSAAIDPDDAAAEMARRFPGVTREALVRFRSGRHREAWRGNVMAVGNSYAFVEPLESSGLLMIATAVQILVSLLPSSRRDPLPSDAANQALAHRWDAIRWFLSIHYRFNGRLDTPFWKEARAETDISGIEPLLRLFAAGAPLTGRDSFTRYLADGAAPLFYGLEGVDTLLLGQEVPARLLPPREPPEQWRARAAAARSLASRGLRQSEALDAYAADPCLNAELLSDSDSWAGERVAVRAG 5uao D 1.88 BS01 FAD D 1 G36 G37 G38 T39 A40 S62 I65 I67 I68 V70 G71 E72 A73 A199 T200 V201 C231 T232 G233 R235 L237 W285 V326 G345 N346 F350 P353 G358 L359 G11 G12 G13 T14 A15 S37 I40 I42 I43 V45 G46 E47 A48 A174 T175 V176 C206 T207 G208 R210 L212 W260 V301 G320 N321 F325 P328 G333 L334 W2EQU4 28032983 PGAIRTVGVIGGGTAGYLTALALKAKRPWLDVALVESADIPIIGVGEATVSYMVMFLHHYLGIDPAEFYQHVRPTWKLGIRFEWGSRPEGFVAPFDWGTGSVGLVGSLRETGNVNEATLQAMLMTEDRVPVYRGEGGHVSLMKYLPFAYHMDNARLVRYLTELAARRGVRHVDATVAEVRLDGPDHVGGLITTDGRRLHYDFYVDCTGFRSLLLEKALGIPFESYASSLFTDAAVTGTLAHGGHLKPYTTATTMNAGWCWTIPTPESDHLGYVFSSAAIDPDDAAAEMARRFPGVTREALVRFRSGRHREAWRGNVMAVGNSYAFVEPLESSGLLMIATAVQILVSLLPSSRRDPLPSDAANQALAHRWDAIRWFLSIHYRFNGRLDTPFWKEARAETDISGIEPLLRLFAAGAPLTGRDSFTRYLADGAAPLFYGLEGVDTLLLGQEVPARLLPPREPPEQWRARAAAARSLASRGLRQSEALDAYAADPCLNAELLSDSDSWAGERVAVRAG 5uf8 A 1.87 BS01 GDP A 1 A27 A28 G29 K30 T31 T32 N126 K127 D129 L130 C159 A160 T161 A11 A12 G13 K14 T15 T16 N110 K111 D113 L114 C143 A144 T145 Q5AND9 EMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRDRIAEAREELQQMLNEDELRDALLLVFANKQDLPNAMNAAEITEKLGLHSIRQRPWYIQATCATTGDGLYEGLEWLSTNL 5uf8 B 1.87 BS01 GDP B 1 A27 A28 G29 K30 T31 T32 N126 K127 D129 L130 C159 A160 T161 A11 A12 G13 K14 T15 T16 N108 K109 D111 L112 C141 A142 T143 Q5AND9 EMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDRPLWRYYFQNTQGIIFVVDSNDRDRIAEAREELQQMLNEDELRDALLLVFANKQDLPNAMNAAEITEKLGLHSIRQRPWYIQATCATTGDGLYEGLEWLSTNL 5uf8 C 1.87 BS01 GDP C 1 A27 A28 G29 K30 T31 T32 N126 K127 D129 L130 C159 A160 T161 A11 A12 G13 K14 T15 T16 N110 K111 D113 L114 C143 A144 T145 Q5AND9 EMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRDRIAEAREELQQMLNEDELRDALLLVFANKQDLPNAMNAAEITEKLGLHSIRQRPWYIQATCATTGDGLYEGLEWLSTNL 5uf8 D 1.87 BS01 GDP D 1 A27 A28 G29 K30 T31 T32 N126 K127 D129 L130 C159 A160 T161 A14 A15 G16 K17 T18 T19 N109 K110 D112 L113 C142 A143 T144 Q5AND9 GNKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGIRPLWRYYFQNTQGIIFVVDSNDRDRIAEAREELQQMLNEDELRDALLLVFANKQDLPNAMNAAEITEKLGLHSIRQRPWYIQATCATTGDGLYEGLEWLSTNL 5ufp A 1.90 BS01 86D A 1 F244 H248 M252 A277 F280 Y281 M289 S292 H293 L296 S304 Y307 M309 T321 I337 C339 N341 F6 H10 M14 A39 F42 Y43 M51 S54 H55 L58 S66 Y69 M71 T83 I95 C97 N99 Q99814 27595393 LDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPPQCIMCVNYVLSE 5ug4 A 2.15 BS01 CA A 1 E33 E75 E32 E74 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNR 5ug4 A 2.15 BS02 CA A 2 E34 P35 E41 E33 P34 E40 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNR 5ug4 A 2.15 BS03 CA C 1 E33 E75 E32 E74 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNR 5ug4 B 2.15 BS01 CA B 1 E33 E75 E32 E74 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLN 5ug4 B 2.15 BS02 CA B 2 E33 E75 E32 E74 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLN 5ug4 B 2.15 BS03 CA B 3 E34 P35 Y36 E41 E33 P34 Y35 E40 2.3.1.57 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLN 5ug4 C 2.15 BS01 CA C 1 E33 E75 E31 E73 2.3.1.57 Q9KL03 SQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 5ug4 C 2.15 BS02 CA C 2 E33 E75 E31 E73 2.3.1.57 Q9KL03 SQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 5ug4 C 2.15 BS03 CA C 3 E34 P35 Y36 E41 E32 P33 Y34 E39 2.3.1.57 Q9KL03 SQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 5uhw A 2.24 BS01 NAD A 1 G12 G14 F15 F16 D37 R38 D39 R42 A74 T75 S79 Q97 K98 P99 N126 Q165 G9 G11 F12 F13 D34 R35 D36 R39 A71 T72 S76 Q94 K95 P96 N123 Q162 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uhw A 2.24 BS02 MG A 1 W24 K25 V27 A30 W21 K22 V24 A27 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uhw B 2.24 BS01 NAD B 1 G12 G14 F15 F16 D37 R38 D39 A74 T75 S79 Q97 K98 P99 N126 Q165 G9 G11 F12 F13 D34 R35 D36 A71 T72 S76 Q94 K95 P96 N123 Q162 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uhw B 2.24 BS02 MG B 1 W24 K25 V27 A30 W21 K22 V24 A27 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5ui2 A 2.10 BS01 EQ3 A 1 L37 I40 W41 Y44 I53 L107 W110 Y111 G114 I151 T152 R155 V158 Y203 L207 C247 L250 L252 V275 T277 W279 F280 M286 W290 I305 L36 I39 W40 Y43 I52 L106 W109 Y110 G113 I150 T151 R154 V157 Y202 L206 C246 L249 L251 V274 T276 W278 F279 M285 W289 I304 P83689 PFTIDTARSIFPETLAADVVPATIARFKQLSAEDQLALIWFAYLEMGKTITIAAPGAANMQFAENTLQEIRQMTPLQQTQAMCDLANRTDTPICRTYASWSPNIKLGFWYELGRFMDQGLVAPIPEGYKLSANANAILVTIQGIDPGQQITVLRNCVVDMGFDTSKLGSYQRVAEPVVPPQEMSQRTKVQIEGVTNSTVLQYMDNLNANDFDNLISLFAEDGALQPPFQKPIVGKENTLRFFREECQNLKLIPERGVSEPTEDGYTQIKVTGKVQTPWFGGNVGMNIAWRFLLNPENKVFFVAIDLLASPKELLNL 5ui2 B 2.10 BS01 EQ3 B 1 L37 I40 W41 Y44 I53 L107 W110 Y111 G114 I151 T152 R155 V158 Y203 L207 P227 F242 C247 L250 L252 V275 T277 W279 F280 M286 W290 I305 L36 I39 W40 Y43 I52 L106 W109 Y110 G113 I150 T151 R154 V157 Y202 L206 P226 F241 C246 L249 L251 V274 T276 W278 F279 M285 W289 I304 P83689 PFTIDTARSIFPETLAADVVPATIARFKQLSAEDQLALIWFAYLEMGKTITIAAPGAANMQFAENTLQEIRQMTPLQQTQAMCDLANRTDTPICRTYASWSPNIKLGFWYELGRFMDQGLVAPIPEGYKLSANANAILVTIQGIDPGQQITVLRNCVVDMGFDTSKLGSYQRVAEPVVPPQEMSQRTKVQIEGVTNSTVLQYMDNLNANDFDNLISLFAEDGALQPPFQKPIVGKENTLRFFREECQNLKLIPERGVSEPTEDGYTQIKVTGKVQTPWFGGNVGMNIAWRFLLNPENKVFFVAIDLLASPKELL 5uib A 2.65 BS01 NAD A 1 I11 G12 G14 F15 F16 D37 R38 D39 A74 T75 T76 S79 Q97 K98 P99 N126 Q165 Y167 H182 I8 G9 G11 F12 F13 D34 R35 D36 A71 T72 T73 S76 Q94 K95 P96 N123 Q162 Y164 H179 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uib A 2.65 BS02 TLA A 1 K98 V161 Q165 D178 L179 H182 Y232 K95 V158 Q162 D175 L176 H179 Y229 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uib A 2.65 BS03 MG A 1 W24 K25 V27 A30 W21 K22 V24 A27 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uib B 2.65 BS01 NAD B 1 G12 G14 F15 F16 D37 R38 T75 T76 S79 Q97 K98 P99 N126 Q165 Y167 I291 G9 G11 F12 F13 D34 R35 T72 T73 S76 Q94 K95 P96 N123 Q162 Y164 I288 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uib B 2.65 BS02 TLA B 1 K98 F127 V161 Q165 D178 L179 H182 Y232 I291 K95 F124 V158 Q162 D175 L176 H179 Y229 I288 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5uib B 2.65 BS03 MG B 1 W24 K25 V27 A30 W21 K22 V24 A27 B9JK80 TELKGALIGCGFFAVNQMHAWKDVKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGFDFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFRWQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIARFILGDVATLTARTKRVNPKIKGEDVATILLDHQNGATSIVDVSYATKLGTEPFPETLIDIDGTQGTIRLSQGYRLEVTGPNGMTISDASPQLLSWASRPWHNIQESVLAIQQHWTDRLSSGGETSTSGADNLKTFALVEAAYESAANGRTVDIGAML 5wqe A 3.13 BS01 NUC B 1 V3 K4 S5 K7 K9 R11 W234 W391 S442 M443 S444 Q446 K480 R484 R485 Y501 N503 R597 F600 H614 E615 S617 Q618 L619 I634 W723 G727 V730 R731 R734 R738 R742 P743 K744 I745 R746 G747 V752 V753 G754 G755 N756 Q767 L771 W774 S775 V784 S791 R792 F793 A794 I795 T796 L797 H800 H803 D807 K810 K811 D814 R815 E819 Y825 G831 W835 Y839 N881 Q882 H972 Q973 Q982 V2 K3 S4 K6 K8 R10 W189 W332 S383 M384 S385 Q387 K421 R425 R426 Y439 N441 R535 F538 H552 E553 S555 Q556 L557 I572 W661 G665 V668 R669 R672 R676 R680 P681 K682 I683 R684 G685 V690 V691 G692 G693 N694 Q705 L709 W712 S713 V722 S729 R730 F731 A732 I733 T734 L735 H738 H741 D745 K748 K749 D752 R753 E757 Y763 G769 W773 Y777 N819 Q820 H878 Q879 Q888 3.1.-.- T0D7A2 27989439 AVKSIKVKLRLDDMPEIRAGLWKLHKEVNAGVRYYTEWLSLLRQENLYRRSPQECDKTAEECKAELLERLRARQVENGHRGPAGSDDELLQLARQLYELLVPQAIGAKGDAQQIARKFLSPLADKDAVRTADVLRALADFGLKPLMRVYTDSEMSSVEWKPLRKGQAVRTWDRDMFQQAIERMMSWESWNQRVGQEYAKLVEQKNRFEQKNFVGQEHLVHLVNQLQQDMKEATGRALRGSDKVFEKWGKLAPDAPFDLYDAEIKNVQRRNTRRFGSHDLFAKLAEPEYQALWREDASFLTRYAVYNSILRKLNHAKMFATFTLPDATAHPIWTRFDKLGGNLHQYTFLFNEFGERRHAIRFHKLLKVENGVAREVDDVTVPISMSEQLDNLLPRDPNEPIALYFRDYGAEQHFTGEFGGAKIQCRRDQLAHMHGARDVYLNVSVRVQSQSEARGERRPPYAAVFRLVGDNHRAFVHFDKLSDYLAEHPDDGKLGSEGLLSGLRVMSVDLGLRTSASISVFRVARKDELKPNSKGRVPFFFPIKGNDNLVAVHERSQLLKLPGETESKDLRAIREERQRTLRQLRTQLAYLRLLVRCGSEDVGRRERSWAKLIEQPVDAANHMTPDWREAFENELQKLKSLHGICSDKEWMDAVYESVRRVWRHMGKQVRDWRKDVRSGERPKIRGYAKDVVGGNSIEQIEYLERQYKFLKSWSFFGKVSGQVIRAEKGSRFAITLREHIDHAKEDRLKKLADRIIMEALGYVYALDERGKGKWVAKYPPCQLILLEELSEYQFNNDRPPSENNQLMQWSHRGVFQELINQAQVHDLLVGTMYAAFSSRFDARTGAPGIRCRRVADDLIPTGEGEIFVSPFSAEEGDFHQIHADLNAAQNLQQRLWSDFDISQIRLRCDWGEVDGELVLIPRLTGKRTADSYSNKVFYTNTGVTYYEREREKLSEEEAELLVEADEAREKSVVLMRDPSGIINRGNWTRQKEFWSMVNQRIEGYLVKQIRSR 5wrq A 2.65 BS01 7TX A 1 D766 L769 H862 G863 R878 G894 I895 Y896 F897 S904 Y907 E988 D106 L109 H202 G203 R218 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wrq B 2.65 BS01 7TX B 1 L769 H862 G863 R878 I879 A880 G894 I895 Y896 F897 S904 Y907 E988 L109 H202 G203 R218 I219 A220 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wry A 2.30 BS01 4YR A 1 D766 L769 H862 G863 R878 A880 Y889 G894 I895 Y896 F897 S904 Y907 E988 D106 L109 H202 G203 R218 A220 Y229 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wry B 2.30 BS01 4YR B 1 E763 D766 L769 D770 H862 G863 R878 A880 Y889 G894 I895 Y896 F897 S904 Y907 E988 E104 D107 L110 D111 H203 G204 R219 A221 Y230 G235 I236 Y237 F238 S245 Y248 E329 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wrz A 2.20 BS01 7U3 A 1 E763 H862 G863 Y889 Y896 F897 A898 K903 S904 Y907 E988 E103 H202 G203 Y229 Y236 F237 A238 K243 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wrz B 2.20 BS01 7U3 B 1 E763 H862 G863 Y896 F897 A898 S904 Y907 E988 E103 H202 G203 Y236 F237 A238 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5ws0 A 2.60 BS01 7U6 A 1 E763 D766 H862 G863 Y896 F897 A898 S904 Y907 E988 E103 D106 H202 G203 Y236 F237 A238 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5ws0 B 2.60 BS01 7U6 B 1 E763 D766 H862 G863 Y889 Y896 F897 S904 Y907 E988 E103 D106 H202 G203 Y229 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5ws1 A 1.90 BS01 7U9 A 1 E763 D766 H862 G863 Y896 F897 S904 Y907 E988 E103 D106 H202 G203 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5ws1 B 1.90 BS01 7U9 B 1 D766 H862 G863 Y896 F897 A898 S904 Y907 E988 D106 H202 G203 Y236 F237 A238 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wtc A 2.20 BS01 7UL A 1 D766 L769 H862 G863 R878 I879 A880 Y889 G894 I895 Y896 F897 S904 Y907 E988 D106 L109 H202 G203 R218 I219 A220 Y229 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wtc B 2.20 BS01 7UL B 1 D766 H862 G863 R878 I879 A880 Y889 G894 I895 Y896 F897 S904 Y907 E988 D106 H202 G203 R218 I219 A220 Y229 G234 I235 Y236 F237 S244 Y247 E328 2.4.2.30 P09874 HMKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5wty B 2.79 BS01 NUC D 1 S107 K108 E111 K140 Y141 S143 H144 E147 Y201 H204 R207 K298 P302 Q305 V347 S349 H350 E353 F388 R391 P480 T481 A482 R485 R486 S488 E492 G524 V525 S527 H528 E531 V562 Y563 S565 H566 D569 Y601 Q604 N608 S60 K61 E64 K93 Y94 S96 H97 E100 Y143 H146 R149 K212 P216 Q219 V261 S263 H264 E267 F302 R305 P394 T395 A396 R399 R400 S402 E406 G438 V439 S441 H442 E445 V476 Y477 S479 H480 D483 Y515 Q518 N522 P47077 28053123 GPEASFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPNNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIF 5wty A 2.79 BS01 NUC C 1 S107 K108 E111 K140 S143 H144 E147 Y201 H204 R207 K298 P302 Q305 V347 S349 H350 E353 T384 F388 P480 T481 A482 R485 R486 S488 V489 E492 G524 V525 S527 H528 E531 V562 Y563 S565 H566 D569 Y601 Q604 N608 S57 K58 E61 K90 S93 H94 E97 Y140 H143 R146 K209 P213 Q216 V258 S260 H261 E264 T295 F299 P391 T392 A393 R396 R397 S399 V400 E403 G435 V436 S438 H439 E442 V473 Y474 S476 H477 D480 Y512 Q515 N519 P47077 28053123 ASFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPNNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIF 5wum A 2.00 BS01 III B 1 R315 N319 V321 G323 T328 E354 W357 S360 N361 A364 E396 W399 R244 N248 V250 G252 T257 E283 W286 S289 N290 A293 E325 W328 P52293 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5wum A 2.00 BS02 III C 1 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 D192 W231 N235 R238 D270 W71 N75 A77 S78 G79 T80 T84 Q110 W113 N117 D121 W160 N164 R167 D199 P52293 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5wun A 2.20 BS01 III B 1 R315 N319 V321 G323 T328 E354 W357 S360 N361 E396 W399 R244 N248 V250 G252 T257 E283 W286 S289 N290 E325 W328 P52293 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5wun A 2.20 BS02 III C 1 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 D192 W231 N235 R238 D270 W71 N75 A77 S78 G79 T80 T84 Q110 W113 N117 D121 W160 N164 R167 D199 P52293 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 5wv1 A 1.90 BS01 RIB A 1 G109 N110 Y111 I155 R163 G109 N110 Y111 I155 R163 3.2.2.22 D9J2T9 DVSFRLSGADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLMHLFNYDGNTITVAVDVTNVYIMGYLALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDTAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSSATISLENSWSGLSKQIQLAQGNNGVFRTPTVLVDSKGNRVQITNVTSNVVTSNIQLLLNTKNI