5b1z A 2.15 BS01 III C 1 E40 F41 Y45 F49 L52 V70 E73 R76 D77 N80 G82 R83 V85 A86 L138 Y139 E40 F41 Y45 F49 L52 V70 E73 R76 D77 N80 G82 R83 V85 A86 L138 Y139 Q07817 MSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAA 5b1z B 2.15 BS01 III D 1 E40 F41 R44 Y45 F49 L52 V70 E73 L74 R76 D77 G82 R83 V85 A86 F90 L138 Y139 E40 F41 R44 Y45 F49 L52 V70 E73 L74 R76 D77 G82 R83 V85 A86 F90 L138 Y139 Q07817 MSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAA 5b4w A 2.60 BS01 III G 1 V292 F294 P325 T395 P396 I397 E399 D414 G415 H416 T417 L433 G434 P435 S437 V261 F263 P278 T348 P349 I350 E352 D367 G368 H369 T370 L386 G387 P388 S390 O43157 27984026 TAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSAGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVAS 5f3o B 2.05 BS01 MN B 1 E51 D55 D116 E119 E51 D55 D111 E114 C4LU64 MSSTTLHNAMQYTAFDVLSSILNLMKADPLYDLLQLNQAYSSQDQEYEKNEFYGDSYLEERASSLVLKFLRKYEQIPFEMYSGLRIHTVKNQTLGEIFDLLHLGEKKKKGDLVESLIGGCVLLSQRENATLFLLFAHALIDYIFYHSSYIYFNANPPKLVKEEIITDIQNWFKDKLFYYRSSLEKYQTD 5f3o B 2.05 BS02 MN B 2 E51 D55 E51 D55 C4LU64 MSSTTLHNAMQYTAFDVLSSILNLMKADPLYDLLQLNQAYSSQDQEYEKNEFYGDSYLEERASSLVLKFLRKYEQIPFEMYSGLRIHTVKNQTLGEIFDLLHLGEKKKKGDLVESLIGGCVLLSQRENATLFLLFAHALIDYIFYHSSYIYFNANPPKLVKEEIITDIQNWFKDKLFYYRSSLEKYQTD 5f4s A 1.72 BS01 P6F A 1 A25 D27 Q28 R29 G30 A31 L68 T94 K125 L127 E163 K205 L248 S249 A250 L275 C276 G277 R278 A24 D26 Q27 R28 G29 A30 L67 T93 K124 L126 E162 K204 L247 S248 A249 L274 C275 G276 R277 4.1.2.40 P63705 ITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEK 5f4s B 1.72 BS01 CA B 1 E238 T241 D242 M326 E237 T240 D241 M325 4.1.2.40 P63705 ITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM 5fb9 A 1.50 BS01 ZN A 1 W21 H26 D139 W1 H6 D119 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fb9 A 1.50 BS02 ZN A 2 D65 H80 H135 D139 D45 H60 H115 D119 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fb9 A 1.50 BS03 ZN A 3 H145 H168 D172 H125 H148 D152 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fba A 1.80 BS04 PO4 A 1 W21 H26 D65 K68 H135 D139 H145 D172 W1 H6 D45 K48 H115 D119 H125 D152 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQP 5fbb A 1.75 BS05 AMP A 1 F81 D83 L144 E147 A151 G152 H168 F61 D63 L124 E127 A131 G132 H148 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbb A 1.75 BS06 CA A 1 D209 D213 D189 D193 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbb B 1.75 BS06 CA B 1 D209 S210 D213 D189 S190 D193 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbc A 1.75 BS04 AS A 1 K68 Y69 F81 D83 L144 H145 E147 A151 G152 N154 H168 D172 K48 Y49 F61 D63 L124 H125 E127 A131 G132 N134 H148 D152 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbd A 1.75 BS04 PO4 A 1 W21 D65 K68 H80 D139 H145 H168 D172 W1 D45 K48 H60 D119 H125 H148 D152 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbd A 1.75 BS05 DCZ A 1 K68 Y69 F81 D83 H145 A151 N154 H168 K48 Y49 F61 D63 H125 A131 N134 H148 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbf A 1.04 BS05 DCM A 2 W21 G22 D65 K68 Y69 H80 D139 H145 H168 D172 W1 G2 D45 K48 Y49 H60 D119 H125 H148 D152 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbg A 1.97 BS02 ZN A 2 N65 H80 H135 D139 N45 H60 H115 D119 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWANTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbg A 1.97 BS04 PO4 A 1 W21 H26 N65 K68 H80 H135 D139 H145 D172 W1 H6 N45 K48 H60 H115 D119 H125 D152 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWANTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbg A 1.97 BS06 DCZ A 2 E177 Y183 E157 Y163 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWANTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQPS 5fbg B 1.97 BS05 GNG B 1 F81 D83 H145 A151 N154 H168 F61 D63 H125 A131 N134 H148 3.1.30.1 P24021 WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWANTYKYTDAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLESPNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHIWDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDPVSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAKAGYRLAAWLDLIASQ 5fbl A 3.37 BS01 5W9 A 1 L374 P381 L383 I562 K564 Y598 I610 E611 P612 V613 V614 N615 A616 L678 I688 L174 P181 L183 I238 K240 Y274 I286 E287 P288 V289 V290 N291 A292 L354 I364 2.7.1.67,2.7.1.67 Q9UBF8 SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 5fbl B 3.37 BS01 GSP B 1 S20 G21 V22 G23 K24 S25 N26 F36 N37 L38 S40 T43 D66 T67 N124 K125 D127 L128 A155 L156 S12 G13 V14 G15 K16 S17 N18 F28 N29 L30 S32 T35 D58 T59 N110 K111 D113 L114 A141 L142 P62491 DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIV 5fbq A 3.79 BS01 5W6 A 1 L374 Y385 W537 I562 K564 Y598 I610 E611 P612 V613 V614 A616 G675 N676 L678 I688 L176 Y187 W215 I240 K242 Y276 I288 E289 P290 V291 V292 A294 G353 N354 L356 I366 2.7.1.67,2.7.1.67 Q9UBF8 SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSDERLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 5fbq B 3.79 BS01 GDP B 1 G21 V22 G23 K24 S25 N26 F36 L38 S40 N124 D127 L128 S154 A155 L156 G13 V14 G15 K16 S17 N18 F28 L30 S32 N110 D113 L114 S140 A141 L142 P62491 DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIV 5fbr A 3.28 BS01 5W7 A 1 L374 P381 I562 K564 Y598 I610 E611 P612 V613 V614 A616 G675 L678 I688 D689 L174 P181 I238 K240 Y274 I286 E287 P288 V289 V290 A292 G351 L354 I364 D365 2.7.1.67,2.7.1.67 Q9UBF8 SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 5fbr B 3.28 BS01 GSP B 1 D19 S20 G21 V22 G23 K24 S25 N26 F36 N37 L38 E39 S40 S42 T43 A68 G69 N124 K125 D127 L128 S154 A155 L156 D12 S13 G14 V15 G16 K17 S18 N19 F29 N30 L31 E32 S33 S35 T36 A61 G62 N113 K114 D116 L117 S143 A144 L145 P62491 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQ 5fbv A 3.29 BS02 GSP B 1 E153 G155 Y159 E26 G28 Y32 2.7.1.67,2.7.1.67 Q9UBF8 SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 5fbv B 3.29 BS01 GSP B 1 S20 G21 V22 G23 K24 S25 N26 F36 N37 L38 S40 K41 S42 T43 A68 G69 N124 K125 D127 L128 S154 A155 L156 S13 G14 V15 G16 K17 S18 N19 F29 N30 L31 S33 K34 S35 T36 A61 G62 N113 K114 D116 L117 S143 A144 L145 P62491 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQ 5fbw A 3.49 BS01 5W8 A 1 L374 P381 I562 K564 Y598 I610 E611 P612 V613 N615 A616 L678 I688 D689 L174 P181 I238 K240 Y274 I286 E287 P288 V289 N291 A292 L354 I364 D365 2.7.1.67,2.7.1.67 Q9UBF8 SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 5fbw A 3.49 BS02 GSP B 1 G155 Y159 G28 Y32 2.7.1.67,2.7.1.67 Q9UBF8 SWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSRGTKLRKLILSRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRS 5fbw B 3.49 BS01 GSP B 1 D19 S20 G21 V22 G23 K24 S25 N26 N37 L38 E39 S40 T43 N124 K125 D127 L128 S154 A155 L156 D12 S13 G14 V15 G16 K17 S18 N19 N30 L31 E32 S33 T36 N110 K111 D113 L114 S140 A141 L142 P62491 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQK 5fd6 A 2.48 BS01 ZN A 1 H36 E84 H91 H93 H32 E80 H87 H89 O07315 AKTLEELATERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYRTVKLFEDAGIIARHDFRDGRSRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIAREHGFRLVDHRLELYGVPLKK 5fd6 A 2.48 BS02 ZN A 2 H90 D92 E111 H128 H86 D88 E107 H124 O07315 AKTLEELATERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYRTVKLFEDAGIIARHDFRDGRSRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIAREHGFRLVDHRLELYGVPLKK 5fg8 A 1.96 BS01 III B 1 R53 K57 E97 F99 E100 I102 V103 D136 K138 E140 L160 W171 F172 G173 F174 A175 G176 T177 P178 G179 Y180 I206 G210 P212 W215 R47 K51 E91 F93 E94 I96 V97 D130 K132 E134 L154 W165 F166 G167 F168 A169 G170 T171 P172 G173 Y174 I200 G204 P206 W209 2.7.11.17 Q00168 CTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQR 5fg8 A 1.96 BS02 ADP A 1 L20 G23 S26 V28 A41 K43 D91 V93 E97 E140 N141 L143 D157 L14 G17 S20 V22 A35 K37 D85 V87 E91 E134 N135 L137 D151 2.7.11.17 Q00168 CTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQR 5fg8 A 1.96 BS03 MG A 1 N141 D157 N135 D151 2.7.11.17 Q00168 CTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQR 5fh1 A 1.55 BS03 GTP A 1 H264 P285 S286 A287 G289 K290 T291 N292 D311 V335 R405 R436 W516 F517 G529 F530 N533 H260 P281 S282 A283 G285 K286 T287 N288 D307 V331 R401 R432 W506 F507 G519 F520 N523 4.1.1.32 P07379 26709450 LHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIDSKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM 5fm2 A 3.30 BS01 PP1 A 1 L730 F735 V738 A756 K758 E775 L779 V804 E805 A807 L881 S891 L21 F26 V29 A47 K49 E66 L70 V95 E96 A98 L147 S157 2.7.10.1 P07949 KILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK 5g3y A 1.18 BS01 ZN A 1 C130 C133 C150 C153 C130 C133 C150 C153 2.7.4.3 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 5g3y A 1.18 BS02 ADP A 1 G10 A11 G12 K13 G14 T15 R123 R127 T136 Y137 H138 F141 Q199 I201 G10 A11 G12 K13 G14 T15 R123 R127 T136 Y137 H138 F141 Q199 I201 2.7.4.3 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 5g3y A 1.18 BS03 ADP A 2 P9 T31 G32 F35 R36 M53 E57 L58 V59 T64 G85 F86 R88 Q92 R127 R160 D162 R171 P9 T31 G32 F35 R36 M53 E57 L58 V59 T64 G85 F86 R88 Q92 R127 R160 D162 R171 2.7.4.3 MNLILLGPPGAGKGTQAEKIVEEYGIPHISTGDMFRAAIKEGTELGLKAKEYMDKGELVPDEVTIGLVKERLSQPDCKKGFLLDGFPRTVAQAEALDKILKELGIKLDAVINIEVPREELLERLTGRRVCRQCGATYHVIFNPPKVEGVCDKCGGELYQRSDDNEETVSNRLDVYEDQTAPLIDYYEKKGLLKNIDGDQDIDAVFADIKAALG 5g3z A 1.89 BS01 ZN A 1 C130 C133 C150 C153 C130 C133 C150 C153 2.7.4.3 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVPDEVTIGIVRERLSKDDCKKGFLLDGFPRTVAQAEALDNILKELGKKLDYVINIEVPKEELMERLTGRRICKTCGATYHLIFNPPKVEGVCDKCGGELYQRADDNEETVANRLDVNMKQTQPLLDFYEEKGYLRNIDGQQDINKVFADIDALLGGL 5g3z A 1.89 BS02 AP5 A 1 P9 G10 A11 G12 K13 G14 T15 T31 G32 F35 R36 M53 E57 L58 V59 T64 G85 F86 R88 Q92 R123 L124 R127 T136 Y137 H138 F141 R160 R171 Q199 I201 P9 G10 A11 G12 K13 G14 T15 T31 G32 F35 R36 M53 E57 L58 V59 T64 G85 F86 R88 Q92 R123 L124 R127 T136 Y137 H138 F141 R160 R171 Q199 I201 2.7.4.3 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVPDEVTIGIVRERLSKDDCKKGFLLDGFPRTVAQAEALDNILKELGKKLDYVINIEVPKEELMERLTGRRICKTCGATYHLIFNPPKVEGVCDKCGGELYQRADDNEETVANRLDVNMKQTQPLLDFYEEKGYLRNIDGQQDINKVFADIDALLGGL 5g40 A 1.69 BS01 ZN A 1 C130 C133 C150 D153 C130 C133 C150 D153 2.7.4.3 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVPDEVTIGIVRERLSKDDCKKGFLLDGFPRTVAQAEALDNILSELGKKLDYVINIEVPKEELMERLTGRRICKTCGATYHLIFNPPKVEGICDKDGGELYQRADDNPETVANRLDVNMKQTQPLLDFYEEKGVLRNIDGQQDINKVFADIKALLGGL 5g40 A 1.69 BS02 ADP A 1 G10 A11 G12 K13 G14 T15 R123 R127 T136 Y137 H138 F141 G197 Q199 I201 G10 A11 G12 K13 G14 T15 R123 R127 T136 Y137 H138 F141 G197 Q199 I201 2.7.4.3 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVPDEVTIGIVRERLSKDDCKKGFLLDGFPRTVAQAEALDNILSELGKKLDYVINIEVPKEELMERLTGRRICKTCGATYHLIFNPPKVEGICDKDGGELYQRADDNPETVANRLDVNMKQTQPLLDFYEEKGVLRNIDGQQDINKVFADIKALLGGL 5g40 A 1.69 BS03 AMP A 1 T31 G32 F35 R36 M53 E57 L58 V59 T64 G85 F86 R88 Q92 R160 T31 G32 F35 R36 M53 E57 L58 V59 T64 G85 F86 R88 Q92 R160 2.7.4.3 MNLVLMGLPGAGKGTQAEKIVEKYGIPHISTGDMFRAAIKEGTELGLKAKSFMDKGELVPDEVTIGIVRERLSKDDCKKGFLLDGFPRTVAQAEALDNILSELGKKLDYVINIEVPKEELMERLTGRRICKTCGATYHLIFNPPKVEGICDKDGGELYQRADDNPETVANRLDVNMKQTQPLLDFYEEKGVLRNIDGQQDINKVFADIKALLGGL 5gmd A 1.50 BS01 DP6 A 1 A14 K17 Y18 W19 K21 N28 S139 G140 S141 R144 S194 R195 M198 D281 A282 A14 K17 Y18 W19 K21 N28 S139 G140 S141 R144 S194 R195 M198 D281 A282 4.1.1.33 Q97UL5 MLKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gmd A 1.50 BS02 AGS A 1 V59 E68 Y72 S94 S106 S107 G110 K190 S194 V59 E68 Y72 S94 S106 S107 G110 K190 S194 4.1.1.33 Q97UL5 MLKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gmd A 1.50 BS03 AMP A 1 R22 G23 L31 K155 E157 E159 L212 R22 G23 L31 K155 E157 E159 L212 4.1.1.33 Q97UL5 MLKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gme A 1.70 BS02 ADP A 1 V59 L64 E68 Y72 S94 S106 S107 G110 K190 V58 L63 E67 Y71 S93 S105 S106 G109 K189 4.1.1.33 Q97UL5 LKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gme A 1.70 BS03 AMP A 1 R22 G23 L31 K155 E157 E159 R21 G22 L30 K154 E156 E158 4.1.1.33 Q97UL5 LKSVTVSAPSNIAVVKYWGKRGDERLNLPLNNSLSITLDDQLSVITKVTLNDKNIVIVNDRILSEDEMKEYAGRVLDTFKKIVGKEFHVKVESKSKFPINAGLASSAAGIAALAFSLNELLELNLKSEELSKIARLGSGSACRSMFGGFVVWNKGEREDGEDSYCYQIFRHDYWSELVDIIPILSEKEKKISSRKGMIRSAETSELMECRLKYIEKTFNEVIEAIRNRDEKKFYYLMMRHSNSMHAVILDSWPSFFYLNDTSIRIMEWIHDYGKAGYTFDAGPNPHIFTTERNIGDILEFLKSLEIKRIIVSKVGDGPKVLSRE 5gpe A 2.01 BS01 PB A 1 C78 V81 N82 C72 V75 N76 Q1LKZ5 27989185 MMRIGELGKKADCLVQTVRFYESEGLLPEPFRLYDEVHLQRLLFIRRCRAKDMTLDEIRQLLNLRDRPELGCGEVNALVDAHIAQVRTKMKELRALERELMDLRRSCDSARTSRECGILNSLA 5gpe A 2.01 BS02 PB B 1 C113 C122 C107 C116 Q1LKZ5 27989185 MMRIGELGKKADCLVQTVRFYESEGLLPEPFRLYDEVHLQRLLFIRRCRAKDMTLDEIRQLLNLRDRPELGCGEVNALVDAHIAQVRTKMKELRALERELMDLRRSCDSARTSRECGILNSLA 5gpj A 3.50 BS01 MG A 1 K250 D253 D723 D727 K730 K223 D226 D689 D693 K696 3.6.1.1 P21616 27922000 AILPDLGTEILIPVCAVIGIAFALFQWLLVSKVKLEGINDHNVVVKCAEIQNAISEGATSFLFTEYKYVGIFMVAFAILIFLFLGSVEGFSTSPQACSYDKTKTCKPALATAIFSTVSFLLGGVTSLVSGFLGMKIATYANARTTLEARKGVGKAFITAFRSGAVMGFLLAANGLLVLYIAINLFKIYYGDDWGGLFEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGKDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAESSCAALVVASISSFGLNHELTAMLYPLIVSSVGILVCLLTTLFATDFFEIKAVKEIEPALKKQLVISTVLMTIGVAVVSFVALPTSFTIFNFGVQKDVKSWQLFLCVAVGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALGYKSVIIPIFAIAISIFVSFTFAAMYGIAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHRIRERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFVSRASITTVDVLTPKVFIGLIVGAMLPYWFSAMTMKSVGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGALVMLTPLVVGILFGVETLSGVLAGSLVSGVQIAISASNTGGAWDNAKKYIEAGASEHARSLGPKGSDCHKAAVIGDTIGDPLKDTSGPSLNILIKLMAVESLVFAPFFATHGGLLFKIF 5gpj C 3.50 BS01 MG C 1 D253 D691 D723 D727 D225 D653 D685 D689 3.6.1.1 P21616 27922000 AAILPDLGTEILIPVCAVIGIAFALFQWLLVSKVKLINDHNVVVKCAEIQNAISEGATSFLFTEYKYVGIFMVAFAILIFLFLGSVEGFSTSPQACSYDKTKTCKPALATAIFSTVSFLLGGVTSLVSGFLGMKIATYANARTTLEARKGVGKAFITAFRSGAVMGFLLAANGLLVLYIAINLFKIYYGDDWGGLFEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGKDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAESSCAALVVASISSFGLNHELTAMLYPLIVSSVGILVCLLTTLFATDFFEVKEIEPALKKQLVISTVLMTIGVAVVSFVALPTSFTIFNFGVQKDVKSWQLFLCVAVGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALGYKSVIIPIFAIAISIFVSFTFAAMYGIAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHRIRERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFVSRASITTVDVLTPKVFIGLIVGAMLPYWFSAMTMKSVGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGALVMLTPLVVGILFGVETLSGVLAGSLVSGVQIAISASNTGGAWDNAKKYIEAGASEHARSLGPKGSDCHKAAVIGDTIGDPLKDTSGPSLNILIKLMAVESLVFAPFFATHGGLLFKIF 5gpj D 3.50 BS01 MG D 1 D279 D283 D507 D242 D246 D469 3.6.1.1 P21616 27922000 AILPDLGTEILIPVCAVIGIAFALFQWLLVSKVKLINDHNVVVKCAEIQNAISEGATSFLFTEYKYVGIFMVAFAILIFLFLGSVEGFSTSPQACSYDKTKTCKPALATAIFSTVSFLLGGVTSLVSGFLGMKIATYANARTTLEARKGVGKAFITAFRSGAVMGFLLAANGLLVLYIAINLFKIYYGDDWGGLFEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAESSCAALVVASISSFGLNHELTAMLYPLIVSSVGILVCLLTTLFATDFFEIAVKEIEPALKKQLVISTVLMTIGVAVVSFVALPTSFTIFNFGVQKDVKSWQLFLCVAVGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALGYKSVIIPIFAIAISIFVSFTFAAMYGIAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHRIRERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFVSRASITTVDVLTPKVFIGLIVGAMLPYWFSAMTMKSVGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGALVMLTPLVVGILFGVETLSGVLAGSLVSGVQIAISASNTGGAWDNAKKYIEAGASEHARSLGPKGSDCHKAAVIGDTIGDPLKDTSGPSLNILIKLMAVESLVFAPFFATHGGLLFKIF 5gpj D 3.50 BS02 MG D 2 K250 D253 D727 K730 K221 D224 D689 K692 3.6.1.1 P21616 27922000 AILPDLGTEILIPVCAVIGIAFALFQWLLVSKVKLINDHNVVVKCAEIQNAISEGATSFLFTEYKYVGIFMVAFAILIFLFLGSVEGFSTSPQACSYDKTKTCKPALATAIFSTVSFLLGGVTSLVSGFLGMKIATYANARTTLEARKGVGKAFITAFRSGAVMGFLLAANGLLVLYIAINLFKIYYGDDWGGLFEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYAESSCAALVVASISSFGLNHELTAMLYPLIVSSVGILVCLLTTLFATDFFEIAVKEIEPALKKQLVISTVLMTIGVAVVSFVALPTSFTIFNFGVQKDVKSWQLFLCVAVGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALGYKSVIIPIFAIAISIFVSFTFAAMYGIAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHRIRERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFVSRASITTVDVLTPKVFIGLIVGAMLPYWFSAMTMKSVGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGALVMLTPLVVGILFGVETLSGVLAGSLVSGVQIAISASNTGGAWDNAKKYIEAGASEHARSLGPKGSDCHKAAVIGDTIGDPLKDTSGPSLNILIKLMAVESLVFAPFFATHGGLLFKIF 5h3t A 2.57 BS01 MGT A 1 Y474 T540 E541 L580 N582 K641 T643 Y660 Y416 T470 E471 L510 N512 K571 T573 Y590 Q8TEQ6 27834343 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPCYLATGSKDQTIRIWSCSRGRGVMILKLPRLWLTLHWPSNQPTQLVSSCFGGELLQWDLTRKYTLFSQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ 5h3t B 2.57 BS01 MGT B 1 Y474 T540 E541 L580 N582 K641 Y660 L686 Y416 T471 E472 L510 N512 K571 Y590 L616 Q8TEQ6 27834343 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGCYLATGSKDQTIRIWSCSRGRGVMILKLPRLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQRRKYTLFSQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQINLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ 5h3t C 2.57 BS01 MGT C 1 Y474 T540 E541 N582 K641 Y660 R684 L686 Y420 T475 E476 N517 K576 Y595 R619 L621 Q8TEQ6 27834343 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGCYLATGSKDQTIRIWSCSRGRGVMILKLPLKRLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ 5h3t D 2.57 BS01 MGT D 1 Y474 T540 E541 L580 N582 K641 Y660 R684 L686 Y421 T476 E477 L515 N517 K576 Y595 R619 L621 Q8TEQ6 27834343 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGCYLATGSKDQTIRIWSCSRGRGVMILKLPRLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQINLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ 5h3u A 2.50 BS01 NUC C 1 N13 W14 Y15 R33 R66 R284 R335 M357 R359 G380 F381 Y383 G400 W422 K428 F705 N11 W12 Y13 R31 R64 R243 R292 M314 R316 G337 F338 Y340 G357 W379 K385 F653 Q8TEQ6 27834343 QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQ 5h9d A 2.68 BS01 III K 1 I159 L162 R163 M196 H199 V283 K286 Y287 K290 I158 L161 R162 M195 H198 V282 K285 Y286 K289 2.5.1.1,2.5.1.30 A0A0D6HKK2 AKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLEMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT 5i2l A 1.85 BS01 CA A 1 D105 D109 F111 E116 D26 D30 F32 E37 Q96C19 27974828 FNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLARLSEIDVSS 5i2l A 1.85 BS02 CA A 2 D141 D143 D145 K147 E152 D62 D64 D66 K68 E73 Q96C19 27974828 FNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLARLSEIDVSS 5inf B 2.75 BS01 HXC B 1 F107 L110 G111 S113 G143 G144 A145 R146 I147 Q148 Y157 G161 A182 G183 G184 Y187 S188 G208 E210 F88 L91 G92 S94 G124 G125 A126 R127 I128 Q129 Y138 G142 A163 G164 G165 Y168 S169 G189 E191 A0ACI9 TSTADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGARFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5inf F 2.75 BS01 HXC B 1 F399 G419 G420 A423 P453 F378 G398 G399 A402 P432 A0ACI9 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGANSAVPILHNLVDDYRRRFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini A 2.85 BS01 HXC A 1 G111 S113 G143 G144 A145 R146 I147 Q148 Y157 G161 A182 G183 G184 Y187 S188 L191 T207 G208 G92 S94 G124 G125 A126 R127 I128 Q129 Y138 G142 A163 G164 G165 Y168 S169 L172 T188 G189 A0ACI9 TSTADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGARRRFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini B 2.85 BS01 HXC B 1 L110 G111 S113 G143 A145 R146 I147 Q148 Y157 G161 A182 G183 G184 Y187 S188 E210 L92 G93 S95 G125 A127 R128 I129 Q130 Y139 G143 A164 G165 G166 Y169 S170 E192 A0ACI9 PTSTADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGARFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini B 2.85 BS02 HXC F 1 F399 G419 G420 A423 V445 F381 G401 G402 A405 V427 A0ACI9 PTSTADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGARFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini C 2.85 BS01 HXC E 1 F399 G419 G420 A423 F379 G399 G400 A403 A0ACI9 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGAFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini D 2.85 BS01 HXC A 1 F399 G419 G420 A423 I454 F382 G402 G403 A406 I437 A0ACI9 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTVGIPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGANSAVPILLVDDYRRRFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini E 2.85 BS01 HXC E 1 G111 S113 G143 G144 A145 R146 I147 Q148 I154 Y157 G161 A182 G183 G184 Y187 T207 G208 E210 G94 S96 G126 G127 A128 R129 I130 Q131 I137 Y140 G144 A165 G166 G167 Y170 T190 G191 E193 A0ACI9 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRTVGIPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGANSAVPLVDDYRRRFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini F 2.85 BS01 HXC B 1 F399 G419 G420 M446 P453 I454 L455 R457 R458 F378 G398 G399 M425 P432 I433 L434 R436 R437 A0ACI9 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGANSAVPILHRRELAAVPPEERAAVKENLVDDYRRRFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5ini F 2.85 BS02 HXC F 1 G111 G143 A145 R146 I147 Q148 I154 Y157 G161 A182 G183 G184 Y187 S188 G90 G122 A124 R125 I126 Q127 I133 Y136 G140 A161 G162 G163 Y166 S167 A0ACI9 STADRIADLAARHEEAVVLAEKKAADRQHLKGKLTARARIDLLLDPGSFVELDEFVRHRPRPYGDGVVTGHGTIDGRQVCVFSHDFTTLGGSMGEAFGSKVVKIYDFAMSVGCPVIGINDSGGARIQEGVMSIAYYTELGVRNVHSSGVIPQISLIMGPCAGGSVYSPALTDFTVMVKDISYMFVTGPEVVSAVMGEQVTAEQLGGPAVHAEVSGNAHYVGDDEQDAISWVQTLLGYLPPNNLDPAPVYDHDCAPGITEADLALDTVIPDSEQQVYDMADVITAVLDDGDYLEIHPDFARNIICALGRVEGHSVAVVANQPRHLAGVLDIDASEKAARFIRFCDSFNIPVLTFMDVPGYLPGVGQEHQGIIRRGIKLFYAYAESTVPKITVITRKAYGGGYAVMGSRQIGADRVMAWPTAEIAVMGANSAVPILHRRELAAVPPEERAAVKENLVDDYRRRFGNPYEAAAHGYVDMVISPSRTRYEVARALASLRNKRQARPARKHGNIPL 5jjv A 2.40 BS01 NUC E 1 K62 R65 N66 N73 L77 L120 S121 A123 T124 N127 K170 S193 K195 V196 R199 R213 N277 Q278 A282 L283 T284 A286 Y287 K290 K305 H309 R312 H313 T340 K62 R65 N66 N73 L77 L112 S113 A115 T116 N119 K162 S185 K187 V188 R191 R205 N269 Q270 A274 L275 T276 A278 Y279 K282 K297 H301 R304 H305 T332 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQSAGNKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEE 5jjv A 2.40 BS02 NUC F 1 K26 L30 S31 R65 L70 G71 N73 T74 Y75 R129 I130 K158 N164 R213 S214 N215 Q285 A286 Y289 E304 K305 N306 G307 A308 H309 K26 L30 S31 R65 L70 G71 N73 T74 Y75 R121 I122 K150 N156 R205 S206 N207 Q277 A278 Y281 E296 K297 N298 G299 A300 H301 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQSAGNKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEE 5jjv B 2.40 BS01 NUC C 1 K62 R65 N66 N73 L77 L120 S121 A123 T124 N127 Y128 S193 K195 V196 R199 R213 K239 N277 Q278 A282 L283 T284 A286 Y287 K290 K305 H309 R312 H313 H335 I343 Y344 K63 R66 N67 N74 L78 L121 S122 A124 T125 N128 Y129 S188 K190 V191 R194 R208 K234 N272 Q273 A277 L278 T279 A281 Y282 K285 K300 H304 R307 H308 H330 I338 Y339 O25386 SMKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGNKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEE 5jjv B 2.40 BS02 NUC D 1 K26 L30 S31 L70 G71 N73 T74 Y75 R129 I130 N159 S214 N215 K239 G240 Q285 A286 Y289 E304 K305 N306 G307 A308 H309 K27 L31 S32 L71 G72 N74 T75 Y76 R130 I131 N160 S209 N210 K234 G235 Q280 A281 Y284 E299 K300 N301 G302 A303 H304 O25386 SMKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGNKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEE 5jk0 A 2.10 BS02 NUC F 1 K26 L30 S31 Q34 R65 L70 G71 N73 T74 Y75 K126 R129 I130 R213 S214 N215 Q285 Y289 E304 K305 N306 G307 A308 H309 K26 L30 S31 Q34 R65 L70 G71 N73 T74 Y75 K122 R125 I126 R198 S199 N200 Q270 Y274 E289 K290 N291 G292 A293 H294 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLIAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN 5jk0 B 2.10 BS01 NUC E 1 K223 K270 N271 K208 K255 N256 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWE 5jk0 B 2.10 BS02 NUC G 1 K62 R65 N66 N73 L77 L120 S121 A123 T124 N127 Y128 S193 V196 R199 R213 N277 Q278 A282 L283 T284 A286 Y287 K290 K305 H309 R312 H313 H335 A336 T340 K62 R65 N66 N73 L77 L116 S117 A119 T120 N123 Y124 S178 V181 R184 R198 N262 Q263 A267 L268 T269 A271 Y272 K275 K290 H294 R297 H298 H320 A321 T325 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWE 5jk0 B 2.10 BS03 NUC H 1 K26 L30 S31 L70 G71 N73 T74 Y75 K126 R129 I130 K158 S214 N215 Q285 Y289 E304 K305 N306 G307 A308 H309 K26 L30 S31 L70 G71 N73 T74 Y75 K122 R125 I126 K154 S199 N200 Q270 Y274 E289 K290 N291 G292 A293 H294 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWE 5jk0 C 2.10 BS01 NUC E 1 K26 L30 S31 Q34 G71 N73 T74 Y75 R213 S214 N215 Q285 Y289 E304 K305 N306 G307 A308 H309 K26 L30 S31 Q34 G71 N73 T74 Y75 R204 S205 N206 Q276 Y280 E295 K296 N297 G298 A299 H300 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNIKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFRLEEAASIWE 5jk0 C 2.10 BS02 NUC F 1 K62 R65 N66 N73 L77 S121 A123 T124 N127 S193 V196 R199 N277 Q278 L283 T284 A286 Y287 H309 H335 A336 S337 T340 K62 R65 N66 N73 L77 S121 A123 T124 N127 S184 V187 R190 N268 Q269 L274 T275 A277 Y278 H300 H326 A327 S328 T331 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNIKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFRLEEAASIWE 5jk0 D 2.10 BS01 NUC G 1 K26 L30 S31 L70 N73 T74 Y75 I130 R213 S214 N215 Q285 Y289 E304 K305 N306 G307 A308 H309 K26 L30 S31 L70 N73 T74 Y75 I130 R205 S206 N207 Q277 Y281 E296 K297 N298 G299 A300 H301 O25386 MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFNSLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHRLEEAASIWEE 5k7z A 2.92 BS01 NUC E 1 T34 S35 M36 K47 A48 Y51 N56 K57 T22 S23 M24 K35 A36 Y39 N44 K45 Q1D4I5 ERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z A 2.92 BS02 NUC F 1 R14 M45 T46 A48 G49 H52 H53 R2 M33 T34 A36 G37 H40 H41 Q1D4I5 ERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z A 2.92 BS03 IVC A 1 W169 K172 W173 F174 K175 G178 L180 W157 K160 W161 F162 K163 G166 L168 Q1D4I5 ERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z A 2.92 BS04 IVC B 1 M69 F72 V109 I112 L113 D128 K131 K132 V135 T157 F161 L164 L168 M57 F60 V97 I100 L101 D116 K119 K120 V123 T145 F149 L152 L156 Q1D4I5 ERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z B 2.92 BS01 NUC E 1 M45 T46 A48 G49 H52 H53 M32 T33 A35 G36 H39 H40 Q1D4I5 RYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z B 2.92 BS02 NUC F 1 T34 S35 M36 K47 Y51 N56 K57 T21 S22 M23 K34 Y38 N43 K44 Q1D4I5 RYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z C 2.92 BS02 IVC D 1 M69 F72 V109 I112 L113 D128 K131 K132 Y134 V135 F161 L164 L168 M57 F60 V97 I100 L101 D116 K119 K120 Y122 V123 F149 L152 L156 Q1D4I5 ERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5k7z D 2.92 BS01 IVC C 1 M69 F72 D128 K131 K132 F161 L164 L168 M56 F59 D115 K118 K119 F148 L151 L155 Q1D4I5 RYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPF 5kmi A 1.87 BS01 6UE A 1 L486 G488 H489 I490 F521 K544 E560 L564 L567 I572 M587 F589 H648 G667 D668 F669 G670 L1 G3 H4 I5 F31 K54 E67 L71 L74 I79 M94 F96 H152 G171 D172 F173 G174 2.7.10.1 P04629 LQGHIIENPQCVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG 5kmj A 2.04 BS01 6UF A 1 G488 H489 I490 N493 L564 L567 I572 V573 F589 V647 H648 G667 D668 G670 G3 H4 I5 N8 L73 L76 I81 V82 F98 V152 H153 G172 D173 G175 2.7.10.1 P04629 LQGHIIENPQACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVL 5kmk A 2.24 BS01 6UG A 1 S484 G485 L486 K544 E560 L564 L567 I572 M587 F589 L641 F646 H648 I666 G667 D668 G670 S1 G2 L3 K55 E68 L72 L75 I80 M95 F97 L147 F152 H154 I172 G173 D174 G176 2.7.10.1 P04629 SGLQGHIIENACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLGHH 5kml A 2.01 BS01 6UH A 1 S474 S475 L476 K544 E560 L564 L567 I572 M587 F589 H648 I666 D668 F669 G670 S1 S2 L3 K50 E65 L69 L72 I77 M92 F94 H148 I166 D168 F169 G170 2.7.10.1 P04629 SSLSPTDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPDKMLVAVKALKESESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG 5kmm A 2.12 BS01 6UJ A 1 L486 F521 K544 E560 L564 M587 F646 H648 D668 G670 L3 F30 K53 E66 L70 M93 F150 H152 D172 G174 2.7.10.1 P04629 SGLQGHIIACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLGH 5kmn A 2.14 BS01 6UK A 1 S474 S475 L476 F521 K544 E560 L564 L567 I572 M587 F589 H648 I666 G667 D668 F669 G670 S1 S2 L3 F29 K50 E65 L69 L72 I77 M92 F94 H148 I166 G167 D168 F169 G170 2.7.10.1 P04629 SSLSPTDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPDKMLVAVKALKESESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG 5kmo A 2.67 BS01 6UM A 1 G517 V524 A542 F589 E590 Y591 M592 G595 L657 F669 G18 V25 A43 F87 E88 Y89 M90 G93 L153 F165 2.7.10.1 P04629 ACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLGH 5kx5 A 2.50 BS01 GTP A 1 G10 Q11 A12 Q15 D69 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D69 D98 A99 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 I231 D0VWZ0 27882198 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDGEE 5kx5 A 2.50 BS04 CA E 1 S158 K166 E196 H197 S158 K166 E196 H197 D0VWZ0 27882198 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDGEE 5kx5 B 2.50 BS03 6YK B 1 Q11 Q15 P175 K176 V177 D179 T221 P222 T223 Y224 G225 R278 Q11 Q15 P173 K174 V175 D177 T219 P220 T221 Y222 G223 R276 D0VWY9 27882198 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 5kx5 B 2.50 BS04 MG B 2 D297 S298 D292 S293 D0VWY9 27882198 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 5kx5 D 2.50 BS01 GDP D 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V177 E183 N206 Y224 L227 N228 G9 Q10 C11 Q14 S137 G140 G141 T142 G143 V174 E180 N203 Y221 L224 N225 D0VWY9 27882198 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5kx5 D 2.50 BS02 MG D 1 S178 T180 E183 S175 T177 E180 D0VWY9 27882198 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5kx5 D 2.50 BS04 6YK D 1 Q11 Q15 K176 V177 D179 T221 P222 T223 Y224 G225 R278 Q10 Q14 K173 V174 D176 T218 P219 T220 Y221 G222 R275 D0VWY9 27882198 REIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 5kx5 F 2.50 BS01 ADP F 1 K74 I148 K150 Q183 K184 Y185 L186 K198 D200 H239 L240 T241 N242 M320 I330 E331 K74 I126 K128 Q151 K152 Y153 L154 K166 D168 H207 L208 T209 N210 M288 I298 E299 E1BQ43 27882198 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNRRREGREGNVWIAKSSILISSEASELLDFIDEVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKLHH 5kzn A 2.80 BS01 MG A 1 I72 D75 L78 L79 I50 D53 L56 L57 Q14416 KKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNA 5kzq A 2.80 BS01 6YS A 1 R57 R61 S143 Y144 S145 A166 S167 T168 D188 Y216 R271 D295 G296 R32 R36 S96 Y97 S98 A119 S120 T121 D141 Y169 R224 D248 G249 Q14416 KVLTLEGDLVLGGLFPVHQKPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLT 5l6l A 2.70 BS01 NUC M 1 K7 F9 R18 R21 K8 F10 R19 R22 Q9AC34 HHARATGKTFRSGNSEAVRLPRDLAFGADVELTLIRSGDVLTIYPSKGSIADLVATLNQMPRPDS 5l6l A 2.70 BS02 NUC N 1 G12 N13 S14 G13 N14 S15 Q9AC34 HHARATGKTFRSGNSEAVRLPRDLAFGADVELTLIRSGDVLTIYPSKGSIADLVATLNQMPRPDS 5l6l D 2.70 BS01 NUC M 1 S11 G12 N13 S14 S16 G17 N18 S19 Q9AC34 HHHHHHARATGKTFRSGNSEAVRLPRDLAFGADVELTLIRSGDVLTIYPSKGSIADLVATLNQMPRPDSVEIRDEDLFPERPGL 5l6l D 2.70 BS02 NUC N 1 R10 R18 P20 R21 R15 R23 P25 R26 Q9AC34 HHHHHHARATGKTFRSGNSEAVRLPRDLAFGADVELTLIRSGDVLTIYPSKGSIADLVATLNQMPRPDSVEIRDEDLFPERPGL 5l6l E 2.70 BS02 NUC N 1 F9 R10 S11 G12 N13 R18 P20 R21 F10 R11 S12 G13 N14 R19 P21 R22 Q9AC34 HHARATGKTFRSGNSEAVRLPRDLAFGADVELTLIRSGDVLTIYPSKGSIADLVATLNQMPRPD 5l6l H 2.70 BS01 NUC M 1 R18 R21 R21 R24 Q9AC34 HHHHARATGKTFRSGNSEAVRLPRDLAFGADVELTLIRSGDVLTIYPSKGSIADLVATLNQMPRPDSVEIRDEDLFPERPG 5lqq A 2.40 BS04 72P A 1 S81 F210 Y214 K248 F249 H251 W254 W260 F274 W275 V277 S26 F155 Y159 K193 F194 H196 W199 W205 F219 W220 V222 3.1.4.39 Q64610 27982588 GSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPLDFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCKGSTKERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCASSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 5m1z A 2.00 BS01 6LW A 1 W169 E170 Q195 R223 G225 M226 E242 Y337 W148 E149 Q174 R202 G204 M205 E221 Y316 3.2.1.55 B8ZY56 GKTFSNVEIFDPPTNYRDPQVLYARPLELSDGTLLGTWENYSPEPPNVWFPIVKSKDGGKTWKEISKVKDTQNNWGLRYQPQLYELPRAFGKYPKGTVLCSGSSIPSDLSETLIEVYASRDKGYTWEFVSHVALGGEALPNPGLTPVWEPFLMTYKEKLILYYSDQRDNATHSQKLVHQTTTDLKKWSKVVDDTKYANYYARPGMPTVAKLPNNEYIYVYEYGGGPNPPAGSDYWFPVYYRLSKDPQKFLNKAHHQIVSNDGTTPAGSPYVVWTPYGGKNGTIVVSCGTRSEIFTNQALGDASAWKKWDVPQPTAYTRSLLTFQKDPDLLMIMGAGILPPAGGKNTVSASVVRLSEVMK 5m5b A 2.01 BS01 SAM A 1 S62 G64 G87 C88 G89 G92 W93 T110 K111 H116 E117 V136 D137 V138 F139 D152 I153 S51 G53 G76 C77 G78 G81 W82 T99 K100 H105 E106 V125 D126 V127 F128 D141 I142 H9A910 ETLGEKWKARLNQMSALEFYSYKKSGITEVCREEARRALKDGVATGGHAVSRGSAKLRWLVERGYLQPYGKVIDLGCGRGGWSYYAATIRKVQEVKGYTKGGPGHEEPMLVQSYGWNIVRLKSGVDVFHMAAEPCDTLLCDIGESSSSPEVEEARTLRVLSMVGDWLEKRPGAFCIKVLCPYTSTMMETLERLQRRYGGGLVRVPLSRNSTHEMYWVSGAKSNTIKSVSTTSQLLLGRMDGPRRPVKYEEDVNLGSGTRAV 5mb9 A 3.20 BS01 ATP A 1 G21 N22 S23 N24 G213 G214 S215 R216 G242 E282 K285 R286 S289 G352 G353 T354 N356 G11 N12 S13 N14 G203 G204 S205 R206 G232 E272 K275 R276 S279 G342 G343 T344 N346 G0RZX9 GERVVIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYVDGDEYYGQQAKNFLVRNPKNTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNVVFTIKDKAEEDAEPSTLTVSEIATRYLRRLVGAASEYLGKKVTSAVITIPTNFTEKQKAALIAAAAAADLEVLQLISEPAAAVLAYDARPEATISDKIIVVADLGGSRSDVTVLASRSGMYTILATVHDYEYHGIALDKVLIDHFSKEFLKKNPGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLIDGLDFASTINRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTPRIAANFRYIFPESTRILAPSTDPSALNPSELQARGAALQASLIQEFETEDIEQSTHAAVTTMPHVTNAIGVVSVSKFVPIIAPETAVPARRTVHGGDVLVKVVEGSTHINVIKREKVWKIGSTLAEAAVRGVKKGAKVEVTINVNTDLTVIVTAREV 5mb9 B 3.20 BS01 III C 1 Q182 I184 S185 I202 S226 M228 Y229 T230 I231 Q397 L400 F404 D408 S412 A416 V417 T418 T419 M420 P421 H422 V423 T424 E447 L557 Q171 I173 S174 I191 S215 M217 Y218 T219 I220 Q386 L389 F393 D397 S401 A405 V406 T407 T408 M409 P410 H411 V412 T413 E430 L482 G0RZX9 ERVVIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYVDGDEYYGQQAKNFLVRNPKNTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNVVFTIKDKAEEDAEPSTLTVSEIATRYLRRLVGAASEYLGKKVTSAVITIPTNFTEKQKAALIAAAAAADLEVLQLISEPAAAVLAYDARPEATISDKIIVVADLGGSRSDVTVLASRSGMYTILATVHDYEYHGIALDKVLIDHFSKEFLKKNPGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLIDGLDFASTINRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTPRIAANFRYIFPESTRILAPSTDPSALNPSELQARGAALQASLIQEFETEDIEQSTHAAVTTMPHVTNAIGVVSVSFVPIIAPETAVPARRTVHVLVKVVEGSTHINVREKVWKIGSTLAEAAVKVEVTINVNTDLTVIVTAREV 5mb9 B 3.20 BS03 MG B 1 D211 Q390 D200 Q379 G0RZX9 ERVVIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYVDGDEYYGQQAKNFLVRNPKNTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNVVFTIKDKAEEDAEPSTLTVSEIATRYLRRLVGAASEYLGKKVTSAVITIPTNFTEKQKAALIAAAAAADLEVLQLISEPAAAVLAYDARPEATISDKIIVVADLGGSRSDVTVLASRSGMYTILATVHDYEYHGIALDKVLIDHFSKEFLKKNPGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLIDGLDFASTINRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTPRIAANFRYIFPESTRILAPSTDPSALNPSELQARGAALQASLIQEFETEDIEQSTHAAVTTMPHVTNAIGVVSVSFVPIIAPETAVPARRTVHVLVKVVEGSTHINVREKVWKIGSTLAEAAVKVEVTINVNTDLTVIVTAREV 5mf6 A 1.87 BS03 7M2 A 1 I61 P62 F64 F82 F86 V115 M157 I52 P53 F55 F73 F77 V106 M148 3.5.1.- Q8N6T7 27990725 PFTADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLE 5mf6 B 1.87 BS01 AR6 B 1 G52 A53 G54 T57 D63 F64 R65 Q113 H133 W188 G214 T215 S216 I219 N240 L241 Q242 G256 Y257 V258 G38 A39 G40 T43 D49 F50 R51 Q99 H119 W167 G193 T194 S195 I198 N219 L220 Q221 G235 Y236 V237 3.5.1.- Q8N6T7 27990725 KGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPK 5mf6 B 1.87 BS03 7M2 B 1 I61 P62 F82 F86 V115 M157 I47 P48 F68 F72 V101 M143 3.5.1.- Q8N6T7 27990725 KGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPK 5mfp A 1.98 BS03 7M5 A 1 I61 P62 F64 F86 V115 M157 I185 I52 P53 F55 F77 V106 M148 I169 3.5.1.- Q8N6T7 27990725 PFTADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLE 5mfz A 2.10 BS03 7M9 A 1 I61 P62 F64 V70 W71 P80 F86 V115 M157 I52 P53 F55 V61 W62 P71 F77 V106 M148 3.5.1.- Q8N6T7 27990725 PFTADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLE 5mgn A 2.07 BS03 7N2 A 1 K15 I61 P62 F64 V70 W71 F86 V115 M136 M157 I185 W188 K6 I52 P53 F55 V61 W62 F77 V106 M127 M148 I169 W172 3.5.1.- Q8N6T7 27990725 PFTADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLE 5mji A 2.00 BS01 7O6 A 1 T11 R13 S19 Q20 T21 P90 I91 T92 L93 N94 C132 G133 N134 E135 D136 T10 R12 S18 Q19 T20 P89 I90 T91 L92 N93 C131 G132 N133 E134 D135 K4REZ6 27981706 ALKALILNTTLRRSPSRSQTQGLIDKAVPLYEKEGIETEVVRVIDHDIEQEYWDDYDDWNAGEKARREDEWPWLLEKIREADILVIATPITLNMCTSAAHVILEKLNLMDELNGDTKQFPLYNKVAGLLMCGNEDGAHHVAGTVLNNLGRLGYSVPPNAAAYWLGPAGTGPGYIEGKGDRHFHTNKLIRFMVANTSHLARMLQETPYTTDLEACAQAAREESDDVFAIRVNVNTPAIRYKRFQKLGEVKVEE 5mlc E 3.90 BS01 NUC C 1 K148 T150 M151 R166 I204 G205 K206 G207 F208 R253 K285 P286 K64 T66 M67 R82 I120 G121 K122 G123 F124 R169 K201 P202 A0A0K9QEC7 27986857 SVDAGIGVMGTKLGMMSFFEEDGTVVPVTVIGFKEGNIVTQVKTESTDGYNAVQVGYERLRDRKLTMPERGHLNKAGVIPMRHLQEFRLVSVDDFTPSQKLLFEELFKEGDMVDISGTTIGKGFQGGIKRHNFKRGLMTHGSKSHRALGSIGAGTTPGHVYKGKKMPGRMGGTKTKIRKLKIMKIDTDLRVVMIKGAVPGKPGNLLRLAPAKIVGKNIP 5mlc G 3.90 BS01 NUC B 1 N39 L41 E42 Q78 R79 V81 K82 T105 R107 N24 L26 E27 Q63 R64 V66 K67 T90 R92 P82192 27986857 INRLKTNYIEKMVPLLKEEFSYSNILEVPKVVKIVVNCGIGDASQNAKGLDAAINELALITGQRPVKTKAKTSIAGFKVREGMTLGIAVTLRGNLMYSFLDRLINLALPRTRDFQGVNPNSFDGHGNYSVGFREQSVFPEIKPEIVGKARGMDVCITTTAKTDKEAYKLLSLMGMPFRE 5mlc L 3.90 BS01 NUC C 1 T110 A233 Q235 T56 A179 Q181 P12629 27986857 TKCTEEWRQLKEAVKKEFAIPHVPLDQRWMFTLEEATGPDIWNTTWYPKSADHVPTDKKWYVVDATDLILGRMASTIAIHIRGKNLASYTPSVDMGAFVIVVNADKVAVSGKKRTQKLYRRHSGRPGGLKEETFDQLQKRIPERIIEHAVRGMLPKGRLGRYLFNHLKVYKGAEHPHQAQQPIDLPLRDKRIRVEK 5mlc O 3.90 BS01 NUC B 1 R16 M17 K18 G19 Y22 E38 R16 M17 K18 G19 Y22 E38 P17353 27986857 MLSPKRTRFRKQHRGRMKGISYRGNRICFGRYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTVRPAETRMGSGKGSPEYWVAVVKPGRILYEISGVAENIARRAVAIAASKMPIRTQFIISG 5mlc P 3.90 BS01 NUC C 1 K12 H13 G14 R15 K16 I17 R55 K56 D59 K60 T63 H71 K72 R74 Q75 R100 N101 G102 G103 T105 R106 R109 K2 H3 G4 R5 K6 I7 R45 K46 D49 K50 T53 H61 K62 R64 Q65 R90 N91 G92 G93 T95 R96 R99 A0A0K9RLJ4 27986857 MKHGRKIHRLSRPADQRRALLRGLTTQLLKHGRIKTTRAKASAMRKYVDKMITLAKEGSLHKRRQALGFIYEKQIVHALFAEVPERYGDRNGGYTRIIRTLPRRGDNAPMAYIELV 5mlc Q 3.90 BS01 NUC B 1 R49 R50 H57 R61 E65 R72 F76 R77 S78 N79 K80 H81 Y83 Q85 M92 H93 T94 M101 Q102 Y111 T116 V117 H149 G150 R151 R1 R2 H9 R13 E17 R24 F28 R29 S30 N31 K32 H33 Y35 Q37 M44 H45 T46 M53 Q54 Y63 T68 V69 H101 G102 R103 A0A0K9QQ60 27986857 RREDRTARHVRIRKKVEGTPERPRLCVFRSNKHLYVQVIDDTKMHTLAAASTMQKAISENIDYSAGPTVEVAQKIGEMIAKSCLEKGITKVAFDRGGYPYHGRVKALADAAREHGLVF 5mlc R 3.90 BS01 NUC C 1 K118 G120 D121 R144 N174 R215 K216 A217 R218 K2 G4 D5 R28 N58 R99 K100 A101 R102 P82413 27986857 VKLGDIMGILNKKAVHAAEELRPVPGIRTGDIVQIRLEVPENKRRLSVYKGIVISRQNAGIHTTIRIRRIIAGVGVEIVFPLYSPNIKEIKVVSHRKVRKARLYYLRDKLPRLS 5mlc X 3.90 BS01 NUC B 1 G129 P130 G71 P72 A0A0K9R4I2 27986857 HKKGAGSTKNGRDSKGQRLGVKIYGDQVAKPGAIIIRQRGTKFHPGKNVGIGKDHTIFALIDGLVKFEKYGPDKKKVSVYPREIQPENPNSYRARKRENFRLQREKKK 5mlc 2 3.90 BS01 NUC C 1 K30 F32 S33 K36 S37 T40 N42 S43 K29 F31 S32 K35 S36 T39 N41 S42 P28804 27986857 AVPKKRTSIYKKRIRKNIWKKKGYWAALKAFSLAKSLSTGNS 5mlc 8 3.90 BS01 NUC B 1 R50 P51 K53 K61 R63 K65 T67 R3 P4 K6 K14 R16 K18 T20 P82411 27986857 SSRPQKKGTAHHMKTRPKKTARWDIKRGPAVYPPLPPLPAEWTIVSS 5sww A 3.15 BS01 NUC E 1 I26 G27 R28 H29 K30 T31 N57 A59 K60 H70 A71 W98 S99 P100 Y130 D131 Y132 I17 G18 R19 H20 K21 T22 N45 A47 K48 H58 A59 W86 S87 P88 Y118 D119 Y120 3.5.4.- P31941 27991903 RHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDSVKMDQHRGFLHNQAKNLLCGFYGRHAALRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQ 5sww C 3.15 BS01 NUC G 1 G27 R28 H29 T31 N57 A59 K60 H70 A71 W98 S99 P100 Y130 D131 Y132 G20 R21 H22 T24 N46 A48 K49 H59 A60 W87 S88 P89 Y119 D120 Y121 3.5.4.- P31941 27991903 GPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGMDQHRGFLHNQAKNLLCGFYGRHAALRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQN 5sz5 A 1.27 BS02 72E A 1 H94 H96 H119 V121 V131 V135 L141 L198 T199 T200 W209 H91 H93 H116 V118 V127 V131 L137 L194 T195 T196 W205 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5t4o A 6.90 BS01 ATP A 1 D170 R171 Q172 T173 G174 K175 T176 A177 F360 G363 I364 R365 Q435 D170 R171 Q172 T173 G174 K175 T176 A177 F360 G363 I364 R365 Q435 3.6.3.14 B7MGF4 MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRNQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 5t4o B 6.90 BS01 ATP B 1 D170 R171 Q172 T173 G174 K175 T176 A177 I364 R365 Q435 D169 R170 Q171 T172 G173 K174 T175 A176 I363 R364 Q434 3.6.3.14 B7MGF4 QLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRNQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 5t4o C 6.90 BS01 ATP C 1 D170 R171 Q172 T173 G174 K175 T176 A177 R365 Q433 K434 Q435 D167 R168 Q169 T170 G171 K172 T173 A174 R362 Q430 K431 Q432 3.6.3.14 B7MGF4 NSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRNQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 5t4o F 6.90 BS01 ADP F 1 A151 G152 V153 G154 K155 T156 V157 N158 Y331 A158 G159 V160 G161 K162 T163 V164 N165 Y338 3.6.3.14 B7MGF2 HHHHHGMATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 5t4p B 6.90 BS01 ATP B 1 D170 R171 Q172 T173 G174 K175 T176 A177 L178 R365 K434 Q435 D169 R170 Q171 T172 G173 K174 T175 A176 L177 R364 K433 Q434 3.6.3.14 B7MGF4 QLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRNQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 5t4p C 6.90 BS01 ATP C 1 G169 D170 R171 Q172 T173 G174 K175 T176 A177 T332 F360 G363 I364 R365 P366 A367 Q435 G166 D167 R168 Q169 T170 G171 K172 T173 A174 T329 F357 G360 I361 R362 P363 A364 Q432 3.6.3.14 B7MGF4 NSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRNQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQ 5t4p E 6.90 BS01 ADP E 1 G150 A151 G152 V153 G154 K155 T156 V157 N158 Y331 P332 F410 G157 A158 G159 V160 G161 K162 T163 V164 N165 Y338 P339 F417 3.6.3.14 B7MGF2 HHHHHGMATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL 5t50 A 1.43 BS01 CA A 1 E118 D120 E129 H134 E118 D120 E129 H134 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t50 A 1.43 BS02 CA A 2 D120 W122 N124 E129 D120 W122 N124 E129 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t52 A 1.70 BS03 NGA A 1 D78 G95 G96 Y97 W122 N124 E126 W127 G211 Q212 D78 G95 G96 Y97 W122 N124 E126 W127 G211 Q212 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t52 B 1.70 BS03 A2G B 1 D78 G95 G96 W122 N124 E126 W127 G211 Q212 D78 G95 G96 W122 N124 E126 W127 G211 Q212 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t54 A 1.65 BS03 FUC A 1 W122 V123 N124 T125 E126 W122 V123 N124 T125 E126 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t55 B 1.43 BS03 BGC B 1 T125 E126 T125 E126 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t5o A 2.75 BS02 CA A 1 E118 D120 E129 H134 S144 E118 D120 E129 H134 S144 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t5o C 2.75 BS01 III c 1 Y97 W122 T125 E126 Y97 W122 T125 E126 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t5o I 2.75 BS01 III i 1 Y97 T125 E126 Y97 T125 E126 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t5p A 1.66 BS01 III a 1 W122 T125 E126 W122 T125 E126 P86993 SELSFNYPNFQSVEDITFQGGASPRNETLQLTPTDSNGIPIRQRAGHAVYSQPFQLRDTSFYTTFTFVIRTTSNSPADGFAIFIAPPDFPVKRYGGYLGLFEPNTATNTSANKVVAVEFDTWVNTEWKEPRYRHIGIDVNSIVSVRVTRWQDKDVFSRSIATAHVGYDGISKILTAFVTYPDGGNYVLSHVVDLAEIFPGDVRIGFSGATGQYETQYIHSWSFSSTSTN 5t77 A 2.00 BS01 ZN A 1 H210 H213 H207 H210 B7IE18 LFSSILFSIATFFSRILGLFRDVLFAKYFGVSYELDAYFIAIMFPFFLRKVFGEGAMSSAFVPLYSEKSGEEKDKFLSSVINGFSLIILALVILSYFFPELIINLFGAGSSHETKILAKKLLLITSPSIYFIFLWAISYSILNTNNKFFWPALTPSISNITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIKHKYYFTIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSFYDKGSISYLQYASRFYLLPYGLFAVSVSTVVLSKISNDRKNFNYHLNDALKTTLFFTIPSMVGLIFLSTPIIRFFYEHGAFTSKDTLITSKILIAYTLGLPFYGIYSTISRSYHAIKNTKTPFIAATIVSLSNIILDIIFGLKYGPIGVALATSIAGIIGVLYLLFSVKTFPIKDFLKISLNSLIMLFVIYLTDFTDNEFWFLIQILIGILVYLIFSSIFYRDLIRRFL 5t77 A 2.00 BS02 CA A 1 E74 D77 E71 D74 B7IE18 LFSSILFSIATFFSRILGLFRDVLFAKYFGVSYELDAYFIAIMFPFFLRKVFGEGAMSSAFVPLYSEKSGEEKDKFLSSVINGFSLIILALVILSYFFPELIINLFGAGSSHETKILAKKLLLITSPSIYFIFLWAISYSILNTNNKFFWPALTPSISNITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIKHKYYFTIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSFYDKGSISYLQYASRFYLLPYGLFAVSVSTVVLSKISNDRKNFNYHLNDALKTTLFFTIPSMVGLIFLSTPIIRFFYEHGAFTSKDTLITSKILIAYTLGLPFYGIYSTISRSYHAIKNTKTPFIAATIVSLSNIILDIIFGLKYGPIGVALATSIAGIIGVLYLLFSVKTFPIKDFLKISLNSLIMLFVIYLTDFTDNEFWFLIQILIGILVYLIFSSIFYRDLIRRFL 5t77 A 2.00 BS03 CA A 2 E318 H319 E315 H316 B7IE18 LFSSILFSIATFFSRILGLFRDVLFAKYFGVSYELDAYFIAIMFPFFLRKVFGEGAMSSAFVPLYSEKSGEEKDKFLSSVINGFSLIILALVILSYFFPELIINLFGAGSSHETKILAKKLLLITSPSIYFIFLWAISYSILNTNNKFFWPALTPSISNITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIKHKYYFTIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSFYDKGSISYLQYASRFYLLPYGLFAVSVSTVVLSKISNDRKNFNYHLNDALKTTLFFTIPSMVGLIFLSTPIIRFFYEHGAFTSKDTLITSKILIAYTLGLPFYGIYSTISRSYHAIKNTKTPFIAATIVSLSNIILDIIFGLKYGPIGVALATSIAGIIGVLYLLFSVKTFPIKDFLKISLNSLIMLFVIYLTDFTDNEFWFLIQILIGILVYLIFSSIFYRDLIRRFL 5t7f A 2.60 BS01 76C A 1 T750 F751 M752 P758 W760 I777 Y813 I825 E826 V828 S831 D832 T833 M900 I910 T553 F554 M555 P561 W563 I580 Y616 I628 E629 V631 S634 D635 T636 M703 I713 2.7.1.153 O35904 VKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNLWSLEQPFSIELIEGRKVNAMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPVYFPALEKILELLREILERELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNRVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES 5t8i A 2.60 BS01 77C A 1 T750 F751 M752 P758 L759 W760 I777 Y813 I825 E826 V827 V828 S831 D832 T833 N836 M900 I910 T550 F551 M552 P558 L559 W560 I577 Y613 I625 E626 V627 V628 S631 D632 T633 N636 M700 I710 2.7.1.153 O35904 VKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNLWSLEQPFSIELIEGRKVNAMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPVYFPALEKILELLREILEYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALR 5td5 A 1.72 BS01 NUC C 1 I209 G210 R211 H212 K213 T214 N240 H253 A254 W281 S282 P283 Y313 D314 Y315 I17 G18 R19 H20 K21 T22 N48 H53 A54 W81 S82 P83 Y113 D114 Y115 3.5.4.- Q9UH17 27991903 RYLMDPDTFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHMGFLCNESGRHAALRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIKAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQL 5tkb A 2.16 BS02 7DJ A 1 H326 M439 L485 N487 I502 M523 Q535 F538 H77 M190 L233 N235 I250 M271 Q283 F286 3.1.4.53 Q08499 VKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 5tkb B 2.16 BS02 7DJ B 1 M439 L485 N487 Y495 I502 M523 Q535 F538 M187 L230 N232 Y240 I247 M268 Q280 F283 3.1.4.53 Q08499 EQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVTKVTSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 5tkb C 2.16 BS02 7DJ C 1 M439 L485 N487 I502 M523 Q535 F538 M188 L230 N232 I247 M268 Q280 F283 3.1.4.53 Q08499 TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 5tkb D 2.16 BS02 7DJ D 1 M439 D484 L485 N487 Y495 I502 M523 Q535 F538 M186 D231 L232 N234 Y242 I249 M270 Q282 F285 3.1.4.53 Q08499 QEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 5tkd A 1.92 BS01 7GL A 1 L595 G596 Q597 V603 V640 K642 E688 Y689 V690 E691 G693 P694 V697 R738 L741 L15 G16 Q17 V23 V33 K35 E81 Y82 V83 E84 G86 P87 V90 R131 L134 2.7.10.2 P29597 FHRVDQKEITQLSHLGQGTRTNVYEGRLRLRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPSTAMDKWGFGATLLEICFDGEAPLRSPSEKEHFYQRQHRLPEPSLATLTSQCLTYEPTQRPSFRTILRDL 5tvo A 1.48 BS01 PYR A 1 S87 I98 T99 S249 H262 S1 I12 T13 S147 H160 4.1.1.50 Q587A7 SLFVMKDRVILITCGTITLLNCVPLICEAVSTVCGEVEWVSFMHKNYSFPWEHLSMAEEFKTLRSHFPPFIFGPIDSDHYFLYFHSDAQLSMTMYGLDRNQTKHWYSDKMLPTGPETAVIREATGLSEVVDDSWILHDLQYEPCGYSINAIRGSEYQTIHITPEEHCSFASYETNTCALNYSKCICGVLRVFDPERFSVIVFIDPDSAVGKSYHSGGTIGVEPEYYPNYEAHHRTVNEYTPGHWVLKVNYVKRA 5tvo B 1.48 BS01 PYR A 1 F28 V82 L83 F2 V56 L57 4.1.1.50 Q587A7 SFEGPEKRLEVIMRVVDGTHVSGLLAHDDDVWQKVIDAICAHIVSREFNEYIRSYVLSE 5u9c A 1.90 BS01 BDF A 1 F165 I169 Q172 K181 A182 F247 F165 I169 Q172 K181 A182 F247 Q56905 MKRKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHFAAETDVDLCEREPARAGIYNHLATEQIAQAAKFCGAWLLYLSSSNVFGGEGKLSYNELDIPLPMNYYGRSKLIGESSVRNACTNNHLIIRAGWMIGGGPDKDHKFVGKIIQQIKAGSTSIKAVSDRLGSITSAMQLCNFIIWAINKRHTGTLHFASSGTISRFDIACAIGDLLNFKGDIIPVHSSVFPLSAPRPYSEGIESIYMSILSDAPKPSLWKSDLAKYVGTFL 5u9c C 1.90 BS02 BDF C 2 E117 D119 P121 R139 R150 E116 D118 P120 R138 R149 Q56905 KRKILITGGTGMLGAYVTSALKDTDYNVIVTERNTLNLSVPEAIFSYITAEKPDVILHFAAETDVDLCEREPARAGIYNHLATEQIAQAAKFCGAWLLYLSSSNVFGGEGKLSYNELDIPLPMNYYGRSKLIGESSVRNACTNNHLIIRAGWMIGGGPDKDHKFVGKIIQQIKAGSTSIKAVSDRLGSITSAMQLCNFIIWAINKRHTGTLHFASSGTISRFDIACAIGDLLNFKGDIIPVHSSVFPLSAPRPYSEGIESIYMSILSDAPKPSLWKSDLAKYVGTFLV 5wsj A 1.65 BS01 RIB A 1 E269 K270 I272 E268 K269 I271 Q7YS85 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVPAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGQEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGKSYTLASSKTDVGAPISGPGIPGQFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLAFPLTNAIKDVLAGV 5wsj A 1.65 BS02 RIB A 2 F37 W78 L119 Y185 W331 F37 W78 L119 Y185 W330 Q7YS85 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVPAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGQEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGKSYTLASSKTDVGAPISGPGIPGQFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLAFPLTNAIKDVLAGV