2n3y A BS01 MH0 A 1 K13 C14 Q16 C17 H18 T28 G29 P30 L35 T40 S47 F48 T49 W59 L64 Y67 L68 T78 K79 M80 F82 I85 L94 K13 C14 Q16 C17 H18 T28 G29 P30 L35 T40 S47 F48 T49 W59 L64 Y67 L68 T78 K79 M80 F82 I85 L94 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSFTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE 2n9x A BS01 III B 1 M1 P2 R11 D19 Q26 K30 K49 T50 K51 F52 L53 V54 P55 H57 L63 I66 I67 R70 M1 P2 R11 D19 Q26 K30 K49 T50 K51 F52 L53 V54 P55 H57 L63 I66 I67 R70 Q9GZQ8 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG 2nb9 A BS01 ZN A 1 C5 C8 C28 C31 C5 C8 C28 C31 Q9A679 MILTCPECASRYFVDDSKVGPDGRVVRCASCGNRWTAFKDEAELELVPR 5b7p A 1.49 BS01 MTA A 1 A36 M37 V78 T104 A105 G106 E198 W199 E218 M220 E221 R240 N244 A10 M11 V52 T78 A79 G80 E172 W173 E192 M193 E194 R213 N217 3.2.2.16,3.2.2.9 ASAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF 5b7p A 1.49 BS02 MTA B 1 F148 V150 F122 V124 3.2.2.16,3.2.2.9 ASAPILIQGAMDVEVETLVAALKDKQELTVGSWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHSSFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFVIDYAKALINGF 5eyo A 2.39 BS01 NUC B 1 R25 H28 N29 R33 R36 K40 S59 R60 R6 H9 N10 R14 R17 K21 S40 R41 27903915 HMADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKAR 5f2c A 1.90 BS01 NAP A 1 I151 T152 P153 W154 K178 A180 S181 P210 G211 G215 F229 T230 G231 E232 T235 E238 I239 G255 E382 F384 I148 T149 P150 W151 K175 A177 S178 P207 G208 G212 F226 T227 G228 E229 T232 E235 I236 G252 E379 F381 LNIMKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5f2c B 1.90 BS01 NAP B 1 I151 T152 P153 W154 K178 A180 S181 G211 G215 F229 G231 E232 T235 E238 G255 E382 F384 I145 T146 P147 W148 K172 A174 S175 G205 G209 F223 G225 E226 T229 E232 G249 E376 F378 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5f2c C 1.90 BS01 NAP C 1 I151 T152 P153 W154 K178 A180 S181 G211 G215 F229 T230 G231 E232 T235 I239 G255 E382 F384 I150 T151 P152 W153 K177 A179 S180 G210 G214 F228 T229 G230 E231 T234 I238 G254 E381 F383 G7VCG0 IDLNIMKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5f2c D 1.90 BS01 NAP D 1 I151 T152 P153 W154 K178 A180 S181 P210 G211 G215 F229 T230 G231 E232 T235 G255 C287 E382 F384 I144 T145 P146 W147 K171 A173 S174 P203 G204 G208 F222 T223 G224 E225 T228 G248 C280 E375 F377 KVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5f2c E 1.90 BS01 NAP E 1 I151 T152 P153 W154 K178 A180 S181 P210 G211 G215 F229 G231 E232 T235 I239 L254 G255 E382 F384 I145 T146 P147 W148 K172 A174 S175 P204 G205 G209 F223 G225 E226 T229 I233 L248 G249 E376 F378 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5f30 A 1.45 BS01 CU A 1 H206 D314 H381 H125 D233 H300 W0DP94 KYVKVQDFYDQLGKYVLVAPGKFSGTVAATDLSTGWTMAWLAAWNYGDTCPIMHHMAAFPSPDPYKEFEFVVNTQGGKNLFIYGVPVTVEDPGEGMKIYRIKYDGTRMNLQRDAAEVSGLGLGVHVTITPEADGYAVGDGQKDICAEFDRETDMVRYAWAFDWDPNVKDLKRAWLDGGTMTIKRLKPTLPGGRYDLQGSKGNKIDWELVPGGELAIEDGKVSGDRPLHSVANDALVFDPRGKWAVASMRLPGVCVVFDRENQVPVAVLAGPKGTPSQFQLVKVDDDTWTVDIPEVISAGHQAGFSPDGQSFLFMNSLRQNNIMVWDSSNHDDPTTWEKKAVVESPDWRGAYPNTFHMVFTPDAKKIYVTMWWPSPTPNGIAVIDAVNWEVLKEVDLGPDMHTLAITYDGKFVVGTLSGYQNTASAIVVMETETDEVLGFLPSPMGHHDNVIVPRTLEDLRISRSTTT 5f30 A 1.45 BS02 CU A 2 K103 H135 H528 K22 H54 H447 W0DP94 KYVKVQDFYDQLGKYVLVAPGKFSGTVAATDLSTGWTMAWLAAWNYGDTCPIMHHMAAFPSPDPYKEFEFVVNTQGGKNLFIYGVPVTVEDPGEGMKIYRIKYDGTRMNLQRDAAEVSGLGLGVHVTITPEADGYAVGDGQKDICAEFDRETDMVRYAWAFDWDPNVKDLKRAWLDGGTMTIKRLKPTLPGGRYDLQGSKGNKIDWELVPGGELAIEDGKVSGDRPLHSVANDALVFDPRGKWAVASMRLPGVCVVFDRENQVPVAVLAGPKGTPSQFQLVKVDDDTWTVDIPEVISAGHQAGFSPDGQSFLFMNSLRQNNIMVWDSSNHDDPTTWEKKAVVESPDWRGAYPNTFHMVFTPDAKKIYVTMWWPSPTPNGIAVIDAVNWEVLKEVDLGPDMHTLAITYDGKFVVGTLSGYQNTASAIVVMETETDEVLGFLPSPMGHHDNVIVPRTLEDLRISRSTTT 5f30 B 1.45 BS02 CU B 2 H135 H528 H54 H447 KYVKVQDFYDQLGKYVLVAPGKFSGTVAATDLSTGWTMAWLAAWNYGDTCPIMHHMAAFPSPDPYKEFEFVVNTQGGKNLFIYGVPVTVEDPGEGMKIYRIKYDGTRMNLQRDAAEVSGLGLGVHVTITPEADGYAVGDGQKDICAEFDRETDMVRYAWAFDWDPNVKDLKRAWLDGGTMTIKRLKPTLPGGRYDLQGSKGNKIDWELVPGGELAIEDGKVSGDRPLHSVANDALVFDPRGKWAVASMRLPGVCVVFDRENQVPVAVLAGPKGTPSQFQLVKVDDDTWTVDIPEVISAGHQAGFSPDGQSFLFMNSLRQNNIMVWDSSNHDDPTTWEKKAVVESPDWRGAYPNTFHMVFTPDAKKIYVTMWWPSPTPNGIAVIDAVNWEVLKEVDLGPDMHTLAITYDGKFVVGTLSGYQNTASAIVVMETETDEVLGFLPSPMGHHDNVIVPRTLEDLRISRSTTT 5f36 A 1.50 BS01 5UE A 1 V1008 V1013 A1060 Y1063 N1064 D1071 I1074 V30 V35 A82 Y85 N86 D93 I96 3.6.1.3 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 5f3a A 1.60 BS01 5U9 A 1 V1008 V1013 A1060 N1064 D1071 I1074 V30 V35 A82 N86 D93 I96 3.6.1.3 Q6PL18 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 5f6c A 3.00 BS01 NUC E 1 S121 A123 V128 M130 A136 G137 G138 I139 S140 R141 I167 R169 T170 R373 S123 A125 V130 M132 A138 G139 G140 I141 S142 R143 I169 R171 T172 R375 3.1.26.12 RHMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM 5f6c A 3.00 BS02 MG A 1 D26 L27 D28 R335 D338 D28 L29 D30 R337 D340 3.1.26.12 RHMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM 5f6c B 3.00 BS01 NUC C 1 S121 V128 G137 G138 I139 S140 R141 R142 I167 R169 T170 S122 V129 G138 G139 I140 S141 R142 R143 I168 R170 T171 3.1.26.12 P21513 HMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEA 5f6c B 3.00 BS03 MG B 1 D28 R216 S393 D29 R217 S394 3.1.26.12 P21513 HMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEA 5f76 B 1.95 BS01 MTA B 1 A88 C89 G90 F187 N205 M206 D230 D232 V246 A86 C87 G88 F185 N203 M204 D228 D230 V244 2.4.2.28 I0B503 KVKVGIIGGTGFDDPNLFKKVGVRQVTTPFGKPSDTLVEGFVGDVACVVLPRHGKGHLIPPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWKSEEEHVCVDMVLEQFRKSVVHVREILLEAVALIGAEDWTKTIEANKALVMSSRQDL 5f76 C 1.95 BS02 MTA C 1 T12 A88 C89 G90 F187 V204 N205 M206 T229 D230 D232 T10 A86 C87 G88 F185 V202 N203 M204 T227 D228 D230 2.4.2.28 I0B503 KVKVGIIGGTGFDDPNLFKKVGVRQVTTPFGKPSDTLVEGFVGDVACVVLPRHGKGHLIPPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWKVCVDMVLEQFRKSVVHVREILLEAVALIGAEDWTKTIEANKALVMSSRQDL 5f77 A 2.02 BS01 ADE A 1 A88 C89 G90 F187 V204 N205 T229 D230 D232 V241 V246 A86 C87 G88 F185 V202 N203 T227 D228 D230 V239 V244 2.4.2.28 I0B503 KVKVGIIGGTGFDDPNLFKKVGVRQVTTPFGKPSDTLVEGFVGDVACVVLPRHGKGHLIPPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWKSEEEHVCVDMVLEQFRKSVVHVREILLEAVALIGAEDWTKTIEANKALVMSSRQDL 5f77 C 2.02 BS01 ADE C 1 A88 C89 G90 F187 V204 N205 T229 D230 D232 A86 C87 G88 F185 V202 N203 T227 D228 D230 2.4.2.28 I0B503 KVKVGIIGGTGFDDPNLFKKVGVRQVTTPFGKPSDTLVEGFVGDVACVVLPRHGKGHLIPPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWKCVDMVLEQFRKSVVHVREILLEAVALIGAEDWTKTIEANKALVMSSRQDLL 5f7g A 1.48 BS01 RET A 1 F16 W19 M20 A33 T53 Y58 L77 W106 K108 F16 W19 M20 A33 T53 Y58 L77 W106 K108 P50120 TRDQNGTWEMESNENFEGWMKALDIDFATRKIAVRLTLTLVIDQDGDNFKVKTTSTFYNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5f7g B 1.48 BS01 RET B 1 W19 M20 A33 T53 Y58 Y60 L77 W106 K108 W19 M20 A33 T53 Y58 Y60 L77 W106 K108 TRDQNGTWEMESNENFEGWMKALDIDFATRKIAVRLTLTLVIDQDGDNFKVKTTSTFYNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5f7x A 1.77 BS01 TBN A 1 P63 A88 C89 G90 F187 V204 N205 M206 T229 D230 D232 V246 P56 A81 C82 G83 F180 V197 N198 M199 T222 D223 D225 V239 2.4.2.28 KVKVGIIGGSGFFKKVGVRQVTTPFGKPSDTLVEGFVGDVACVVLPRHGKGHLIPPSEVNYRANVWALKDLGCTHILATNACGSLQEDLVPGDFVVLNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWKSEEEHVCVDMVLEQFRKSVVHVREILLEAVALIGAEDWTKTIEANKALVMSSRLDL 5f8p A 2.20 BS01 FIJ A 1 V83 I85 L90 T92 P93 Y108 L109 S229 W230 H231 E234 V57 I59 L64 T66 P67 Y82 L83 S170 W171 H172 E175 1.14.11.- LESHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKTEAEIAAACETFLKLNDYLQIETIQALEELAAKEDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCELEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 5f8p A 2.20 BS02 AKG A 1 R96 Y108 N205 H231 V244 Y295 V309 R316 S318 T320 R70 Y82 N146 H172 V185 Y225 V239 R246 S248 T250 1.14.11.- LESHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKTEAEIAAACETFLKLNDYLQIETIQALEELAAKEDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCELEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 5f8z A 1.50 BS01 III B 1 H57 D60 V96 S97 E98 G99 Y174 K192 G193 S195 S214 W215 G216 H44 D47 V87 S88 E89 G90 Y165 K185 G186 S188 S207 W208 G209 3.4.21.34 P03952 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 5f9k A 2.18 BS01 DUP A 1 R64 S65 G66 R64 S65 G66 3.6.1.23 Q54BW5 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEID 5f9k B 2.18 BS01 DUP B 1 R64 S65 G66 R107 R64 S65 G66 R107 3.6.1.23 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEIDET 5f9k B 2.18 BS02 MG B 1 V79 D81 V79 D81 3.6.1.23 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEIDET 5f9k B 2.18 BS03 MG B 2 R64 S65 Q110 R64 S65 Q110 3.6.1.23 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEIDET 5f9k B 2.18 BS04 MG B 3 R60 I61 R60 I61 3.6.1.23 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEIDET 5f9k B 2.18 BS05 DUP C 1 A77 G78 V79 I80 D81 Y84 G89 A77 G78 V79 I80 D81 Y84 G89 3.6.1.23 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEIDET 5f9k C 2.18 BS02 MG C 1 R60 P63 R60 P63 3.6.1.23 Q54BW5 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEID 5f9k C 2.18 BS03 DUP C 1 R64 S65 G66 Q110 R64 S65 G66 Q110 3.6.1.23 Q54BW5 GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQIAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDFKVAVGDRVAQLIFERIVTPEPLEVDEID 5fak B 1.87 BS01 ADE B 1 A88 C89 G90 F187 V204 N205 T229 D232 A86 C87 G88 F185 V202 N203 T227 D230 2.4.2.28 I0B503 KVKVGIIGGTGFDDPNLFKKVGVRQVTTPFGKPSDTLVEGFVGDVACVVLPRHGKGHLIPPSEVNYRANVWALKDLGCTHILATTACGSLQEDLVPGDFVVLNQFMDKTWGRENTFYGSKPDSLKGVLHMPMAEPFCERTRQILIQAARNKSINVYDKKTMDKSACIHPCVHAEGSAVTINGPRFSTRCESFIHKAMGLDIVNMTLVPEVSLAREAGLSYASIAIVTDFDCWKEHVCVDMVLEQFRKSVVHVREILLEAVALIGAEDWTKTIEANKALVMSSRQDL 5faz A 1.40 BS01 RET A 1 F16 Q38 T53 F57 L77 W106 K108 F16 Q38 T53 F57 L77 W106 K108 P50120 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTLVIDQDGDNFKVKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5faz B 1.40 BS01 RET B 1 F16 Y19 M20 I25 A33 Q38 V51 T53 Y60 L77 K108 L117 L119 F16 Y19 M20 I25 A33 Q38 V51 T53 Y60 L77 K108 L117 L119 TRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTLVIDQDGDNFKVKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKKWIEGDKLYLELTCGDQVCRQVFKKK 5fb2 A 1.80 BS01 NUC B 1 K17 L24 N31 G34 H35 G38 Y39 Y41 A42 F104 F108 K16 L23 N30 G33 H34 G37 Y38 Y40 A41 F103 F107 Q5Y812 EFTYSYLFRMISHEMKQKADQKLEQLDITNEQGHTLGYLYAHQQDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVEAFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ 5fb7 A 1.50 BS01 ACD A 1 I18 F25 L41 G44 L47 T51 I83 N109 Q113 A117 L120 S121 S140 I147 I12 F19 L35 G38 L41 T45 I77 N103 Q107 A111 L114 S115 S134 I141 A0A093VKV7 DISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fb7 A 1.50 BS02 ACD A 2 F11 L72 V76 L79 V124 V128 I135 S136 L139 S140 I143 F5 L66 V70 L73 V118 V122 I129 S130 L133 S134 I137 A0A093VKV7 DISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fb7 B 1.50 BS01 ACD B 1 F25 G44 L47 T51 I83 N109 Q113 A117 L120 S121 S140 I147 F19 G38 L41 T45 I77 N103 Q107 A111 L114 S115 S134 I141 A0A093VKV7 DISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fb7 B 1.50 BS02 ACD B 2 F11 I15 L72 V76 L79 V124 I135 S136 L139 S140 F5 I9 L66 V70 L73 V118 I129 S130 L133 S134 A0A093VKV7 DISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fb7 C 1.50 BS01 ACD C 1 F25 L40 L47 T51 I83 L90 N109 L110 Q113 A117 L120 S121 V124 S140 I147 F23 L38 L45 T49 I81 L88 N107 L108 Q111 A115 L118 S119 V122 S138 I145 A0A093VKV7 KVKRDISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fb7 C 1.50 BS02 ACD C 2 V14 I15 L64 A69 L72 V73 V76 V124 S136 L139 S140 I143 V12 I13 L62 A67 L70 V71 V74 V122 S134 L137 S138 I141 A0A093VKV7 KVKRDISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fb7 D 1.50 BS01 ACD D 1 F25 L47 I83 L90 N109 L110 Q113 A117 S121 S140 I147 F23 L45 I81 L88 N107 L108 Q111 A115 S119 S138 I145 A0A093VKV7 KVKRDISAFQKVIQDISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGT 5fbj A 2.42 BS01 AKG A 1 Y272 W310 S318 H321 D323 N327 L329 K336 H400 V402 S412 W414 Y92 W130 S138 H141 D143 N147 L149 K156 H220 V222 S232 W234 1.14.11.27 Q8N371 GSTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 5fbj A 2.42 BS02 NMM A 1 E238 Y243 Y272 Q275 W310 S318 H321 D323 W414 E58 Y63 Y92 Q95 W130 S138 H141 D143 W234 1.14.11.27 Q8N371 GSTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 5fpf A 2.60 BS02 5ZI A 1 H1031 G1032 S1033 F1035 A1038 I1039 G1043 F1044 D1045 H1048 Y1050 I1059 Y1060 A1062 S1068 Y1071 I1075 H80 G81 S82 F84 A87 I88 G92 F93 D94 H97 Y99 I108 Y109 A111 S117 Y120 I124 Q9H2K2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQF 5fpf B 2.60 BS02 5ZI B 1 H1031 G1032 S1033 F1035 A1038 I1039 K1042 G1043 F1044 D1045 H1048 Y1050 I1059 Y1060 F1061 A1062 K1067 S1068 Y1071 H80 G81 S82 F84 A87 I88 K91 G92 F93 D94 H97 Y99 I108 Y109 F110 A111 K116 S117 Y120 Q9H2K2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQF 5fpg A 2.75 BS02 Q28 A 1 H1031 G1032 F1035 A1038 I1039 K1042 G1043 D1045 H1048 Y1050 I1059 Y1060 F1061 A1062 S1068 Y1071 I1075 E1138 H80 G81 F84 A87 I88 K91 G92 D94 H97 Y99 I108 Y109 F110 A111 S117 Y120 I124 E182 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 5fq4 A 1.90 BS01 CA A 1 R408 D411 D478 K480 R386 D389 D456 K458 Q8A5H6 TADLIFPSISASIASAVGGEIYNYAGFFAQYYEQKPESNQYNTLCEYTFTESSQQMDYSYRILFAGALEDAKQVLEKTTNPADRFATTILRAYAFQIMVDNTSDSPYSEALATPKWDTGETVYKGILGEIDAAEAALDGSGMDVPDLIFNKNIAQWKGFANALRLRMYLRFIDANIDAASYTEKVKTLVQNNEFFTGDVKLDCFLDETDKRNPWYNTNAVGLTGNHCAAYPLVSYLSSTGDPRIAYGISKTDADGKYVGQLPGGKTHMQSILGTDNWKNKNVSAIDYSIGATKPVYFFTQAELQFLIAEVYARFHNDDANAKSAYEAGVTADFAVRGFAGQENTILEGACAWSAASTQADKLNLIYMQKWVSLFYMDHMEAWSEIRRTDCPKLSSYSAAQIQASESVYTPGELVAPWTNGLEAGGLMKRMTYPLSARQQNVNTPAGVPGSTPVWWDIK 5gjh A 1.20 BS01 III B 1 R65 R83 S85 Q86 S87 S93 Q103 H104 F105 K106 M108 L117 W118 Q140 R10 R28 S30 Q31 S32 S38 Q48 H49 F50 K51 M53 L62 W63 Q85 GSWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTRED 5gjh C 1.20 BS01 III D 1 R65 R83 S85 S87 S93 Q103 H104 F105 K106 L117 W118 Q140 R9 R27 S29 S31 S37 Q47 H48 F49 K50 L61 W62 Q84 SWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTRED 5gji A 0.90 BS01 III B 1 R340 R358 A360 S361 T369 K379 L380 K382 F392 S393 D394 P395 Q415 Y416 N417 L420 R17 R35 A37 S38 T46 K56 L57 K59 F69 S70 D71 P72 Q92 Y93 N94 L97 P27986 SNMSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 5gl3 A 2.40 BS02 MG A 2 E115 D157 G158 N160 E161 E115 D157 G158 N160 E161 B6YTD8 27907125 MIAHLINTDIGNRGVLKVYLDYRRKNFNFLHNSTKMFLDNLERVLIVTGFPIPPMMVAETDGPPGALAIYRAVEMLGGKAEILTYSEVEKALEPFGVSLARTPEPEDYSLIISVETPGRAADGRYYSMSALEIKRDPLDGIFLKARALGIPTIGVGDGGNEIGMGKIRELVVGHVPHGEKIASVVETDELIVSAVSNWGAYGLVAQASIEVGRNLLEGWDERRVIEAISSAGLIDGVSKTLAPSVDGIRLMVHEGIVELLKAVVDEAIL 5gl3 C 2.40 BS02 MG C 2 E115 M128 D157 N160 E161 E114 M127 D156 N159 E160 27907125 IAHLINTDIGNRGVLKVYLDYRRKNFNFLHNSTKMFLDNLERVLIVTGFPIPPMMVAETDGPPGALAIYRAVEMLGGKAEILTYSEVEKALEPFGVSLARTPEPEDYSLIISVETPGRAADGRYYSMSALEIKRDPLDGIFLKARALGIPTIGVGDGGNEIGMGKIRELVVGHVPHGEKIASVVETDELIVSAVSNWGAYGLVAQASIEVGRNLLEGWDERRVIEAISSAGLIDGVSKTLAPSVDGIRLMVHEGIVELLKAVVDEAIL 5gl3 D 2.40 BS02 MG D 2 E115 M128 D157 G158 E161 E115 M128 D157 G158 E161 B6YTD8 27907125 MIAHLINTDIGNRGVLKVYLDYRRKNFNFLHNSTKMFLDNLERVLIVTGFPIPPMMVAETDGPPGALAIYRAVEMLGGKAEILTYSEVEKALEPFGVSLARTPEPEDYSLIISVETPGRAADGRYYSMSALEIKRDPLDGIFLKARALGIPTIGVGDGGNEIGMGKIRELVVGHVPHGEKIASVVETDELIVSAVSNWGAYGLVAQASIEVGRNLLEGWDERRVIEAISSAGLIDGVSKTLAPSVDGIRLMVHEGIVELLKAVVDEAIL 5gl3 E 2.40 BS01 MG E 1 E59 D61 E115 D157 D246 E59 D61 E115 D157 D246 B6YTD8 27907125 MIAHLINTDIGNRGVLKVYLDYRRKNFNFLHNSTKMFLDNLERVLIVTGFPIPPMMVAETDGPPGALAIYRAVEMLGGKAEILTYSEVEKALEPFGVSLARTPEPEDYSLIISVETPGRAADGRYYSMSALEIKRDPLDGIFLKARALGIPTIGVGDGGNEIGMGKIRELVVGHVPHGEKIASVVETDELIVSAVSNWGAYGLVAQASIEVGRNLLEGWDERRVIEAISSAGLIDGVSKTLAPSVDGIRLMVHEGIVELLKAVVDEAIL 5gl4 A 2.20 BS02 MN A 2 E115 D157 G158 E161 E115 D157 G158 E161 B6YTD8 27907125 MIAHLINTDIGNRGVLKVYLDYRRKNFNFLHNSTKMFLDNLERVLIVTGFPIPPMMVAETDGPPGALAIYRAVEMLGGKAEILTYSEVEKALEPFGVSLARTPEPEDYSLIISVETPGRAADGRYYSMSALEIKRDPLDGIFLKARALGIPTIGVGDGGNEIGMGKIRELVVGHVPHGEKIASVVETDELIVSAVSNWGAYGLVAQASIEVGRNLLEGWDERRVIEAISSAGLIDGVSKTLAPSVDGIRLMVHEGIVELLKAVVDEAIL 5gn8 A 2.81 BS01 CA A 1 E27 E62 H65 E107 V110 E18 E53 H56 E98 V101 1.16.3.1 P02794 QNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGD 5gn8 B 2.81 BS01 CA B 1 Q58 E61 K140 D144 Q55 E58 K137 D141 1.16.3.1 STSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLIKELGDHV 5gqr B 3.50 BS01 III C 1 R138 S162 G186 S187 A209 G210 E231 Y234 F279 F281 D303 S305 W325 W353 D375 S377 K397 F401 R421 R423 R102 S126 G150 S151 A173 G174 E195 Y198 F243 F245 D267 S269 W289 W317 D339 S341 K361 F365 R385 R387 2.7.11.1 Q9FII5 27449136 FSPQLLSLLSLKTSLSGPPSAFQDWKVPDAVWCSWSGVVCDNVTAQVISLDLSHRNLSGRIPIQIRYLSSLLYLNLSGNSLEGSFPTSIFDLTKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNGFTGEIPESYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIPNYVGCKSFYRIELQGNSLNGTIPWDIGHCEKLLCLNLSQNHLNGIIPWEISTLPSIADVDLSHNLLTGTIPSDFGSSKTITTFNVSYNQLIGPIPSGSFAHLNPSFFSSNEGLCGDLVGKPCN 5gqr K 3.50 BS01 III C 1 T53 L54 V55 T27 L28 V29 2.7.11.1 27449136 NMEGDALHSLRANLVDPNNVLQSWDPTLVNPCTWFHVTCNNENSVIRVDLGNADLSGQLVPQLGQLKNLQYLELYSNNITGPVPSDLGNLTNLVSLDLYLNSFTGPIPDSLGKLFKLRFLRLNNNSLTGPIPMSLTNIMTLQVLDLSNNRLSGSVPDNGSFSLFTPISFANNLDLCGPVTSRPCP 5gr8 A 2.59 BS01 III J 1 Y153 Y155 V175 Y177 D179 V198 E199 Y203 Y225 H227 F249 T271 D273 S275 V297 N321 K345 D348 F371 Y395 F419 D441 I443 I463 N465 R487 I489 Y125 Y127 V147 Y149 D151 V170 E171 Y175 Y197 H199 F221 T243 D245 S247 V269 N293 K317 D320 F343 Y367 F391 D413 I415 I435 N437 R459 I461 2.7.11.1 Q9SSL9 25475059 LNSDGLTLLSLLKHLDRVPPQVTSTWKINASEATPCNWFGITCDDSKNVASLNFTRSRVSGQLGPEIGELKSLQILDLSTNNFSGTIPSTLGNCTKLATLDLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFRIPKLQVLYLDYNNLTGPIPQSIGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHRNKLVGSLPESLNLLGNLTTLFVGNNSLQGPVRFGSPNCKNLLTLDLSYNEFEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLSGSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLRKLESLELFENRFSGEIPIEIWKSQSLTQLLVYQNNLTGELPVEMTEMKKLKIATLFNNSFYGAIPPGLGVNSSLEEVDFIGNKLTGEIPPNLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFILRENNLSGLLPEFSQDHSLSFLDFNSNNFEGPIPGSLGSCKNLSSINLSRNRFTGQIPPQLGNLQNLGYMNLSRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQFLPELKKLSTLQIARNAFGGEIPSSIGLIEDLIYDLDLSGNGLTGEIPAKLGDLIKLTRLNISNNNLTGSLSVLKGLTSLLHVDVSNNQFTGPIPDNLEGQLLSEPSSFSGNPNLCIP 5gr8 D 2.59 BS01 III P 1 Y155 D179 Y203 Y225 H227 F249 D273 S275 V297 N321 K345 D348 F371 Y395 F419 E439 D441 I443 I463 N465 R487 Y127 D151 Y175 Y197 H199 F221 D245 S247 V269 N293 K317 D320 F343 Y367 F391 E411 D413 I415 I435 N437 R459 2.7.11.1 25475059 LNSDGLTLLSLLKHLDRVPPQVTSTWKINASEATPCNWFGITCDDSKNVASLNFTRSRVSGQLGPEIGELKSLQILDLSTNNFSGTIPSTLGNCTKLATLDLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFRIPKLQVLYLDYNNLTGPIPQSIGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHRNKLVGSLPESLNLLGNLTTLFVGNNSLQGPVRFGSPNCKNLLTLDLSYNEFEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLSGSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLRKLESLELFENRFSGEIPIEIWKSQSLTQLLVYQNNLTGELPVEMTEMKKLKIATLFNNSFYGAIPPGLGVNSSLEEVDFIGNKLTGEIPPNLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFILRENNLSGLLPEFSQDHSLSFLDFNSNNFEGPIPGSLGSCKNLSSINLSRNRFTGQIPPQLGNLQNLGYMNLSRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQFLPELKKLSTLQIARNAFGGEIPSSIGLIEDLIYDLDLSGNGLTGEIPAKLGDLIKLTRLNISNNNLTGSLSVLKGLTSLLHVDVSNNQFTGPIPDNLEGQLLSEPSSFSGNPNLCIP 5h2v A 2.80 BS01 III B 1 Q350 D353 E396 C429 N430 Q434 H470 A473 A474 N477 Q335 D338 E381 C414 N415 Q419 H455 A458 A459 N462 P32337 ALPEEVNRTLLQIVQAFASNQIRSVAEKALSEEWITENNIEYLLTFLAEQAAFSQDTTVAALSAVLFRKLALKAPITHIRKEVLAQIRSSLLKGFLSERADSIRHKLSDAIAECVQDDLPAWPELLQALIESLKSGNPNFRESSFRILTTVPYLITAVDINSILPIFQSGFTDASDNVKIAAVTAFVGYFKQLPKSEWSKLGILLPSLLNSLPRFLDDGKDDALASVFESLIELVELAPKLFKDMFDQIIQFTDMVIKNKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVSIDDDDAAEWIESDDTDDEEEVTYDHARQALDRVALKLGGEYLAAPLFQYLQQMITSTEWRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAAKNKFIKYYDTLMPLLLNVLKVNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDALRSYLEQSWSRICRILGDDFVPLLPIVIPPLLITAKATQDVGLIEEEEAANFQQYPDWDVVKHIAIHTSVLDDKVSAMELLQSYATLLRGQFAVYVKEVMEEIALPSLDFYLHDGVRAAGATLIPILLSCLLAANEELVLLWHKASSKLIGGLMSEPMPEITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDDEYNEDFTDEDLLDEINKSIAAVLKTTNGHYLKNLENIWPMINTFLLDNEPILVIFALVVIGDLIQYGGEQTASMKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAPSTYADVCIPTLDTLVQIVDGSKLEENRSSTENASAAIAKILYAYDTYTANWFKTLPTITDKEAASFNYQFLSQLIEPIVCAQSNISAVVDSVIQALNERSLEGQTVISSVKKLLGFLDAMAIFNRYPADIMEKVHKWF 5h2w A 2.50 BS01 III B 1 D286 R321 N325 V327 T328 G329 T334 K359 E360 W363 S366 N367 A370 E402 W405 D198 R233 N237 V239 T240 G241 T246 K271 E272 W275 S278 N279 A282 E314 W317 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEANENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 5h2w A 2.50 BS02 III B 2 L115 S116 R117 P121 W153 N157 A159 S160 G161 T162 T166 Q192 W195 N199 G202 D203 W237 N241 R244 K246 K247 D276 L27 S28 R29 P33 W65 N69 A71 S72 G73 T74 T78 Q104 W107 N111 G114 D115 W149 N153 R156 K158 K159 D188 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEANENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 5h2w C 2.50 BS01 III D 1 L115 S116 R117 E118 P121 W153 N157 A159 S160 G161 T162 T166 E188 Q192 W195 N199 G202 D203 W237 N241 R244 K246 K247 D276 D286 R321 N325 V327 T328 G329 T334 K359 E360 W363 S366 N367 A370 E402 W405 L27 S28 R29 E30 P33 W65 N69 A71 S72 G73 T74 T78 E100 Q104 W107 N111 G114 D115 W149 N153 R156 K158 K159 D188 D198 R233 N237 V239 T240 G241 T246 K271 E272 W275 S278 N279 A282 E314 W317 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKNENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF 5h2x A 2.20 BS01 III B 1 S116 R117 E118 P121 W153 N157 A159 S160 G161 T162 T166 Q192 W195 N199 G202 D203 W237 N241 R244 K247 D276 R321 N325 V327 T328 G329 T334 K359 E360 W363 S366 N367 E402 W405 S29 R30 E31 P34 W66 N70 A72 S73 G74 T75 T79 Q105 W108 N112 G115 D116 W150 N154 R157 K160 D189 R234 N238 V240 T241 G242 T247 K272 E273 W276 S279 N280 E315 W318 ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEANENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYFG 5h4i B 2.00 BS01 7HQ B 1 D129 Y130 S135 Y150 G151 Y161 D113 Y114 S119 Y134 G135 Y145 ETTDGVYRVMTRRLLGSTQVGVGVMQEGVFHTMWHVTKGAALRSGEGRLDPYWGDVKQDLVSYCGPWKLDAAWDGLSEVQLLAVPPGERAKNIQTLPGIFKTKDGDIGAVALDYPAGTSGSPILDKCGRVIGLYGNGVVIKNGSYVSAITQGKRE 5hl9 A 2.70 BS01 AIX A 1 S510 K513 D553 S572 N574 T682 T699 G700 T701 T702 N703 Y734 S408 K411 D451 S470 N472 T580 T597 G598 T599 T600 N601 Y632 2.4.1.129,3.4.-.- P02919 27899450 LLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISNGEQRLFVPRSGFPDLLVDTLLATEDRHFYTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPRGISPQPAFMQLVRQELQAKLVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQS 5hl9 A 2.70 BS02 M0E A 1 E233 Q271 K274 N275 R286 Y315 E323 V354 K355 G356 A357 S358 I359 E164 Q174 K177 N178 R189 Y218 E226 V257 K258 G259 A260 S261 I262 2.4.1.129,3.4.-.- P02919 27899450 LLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISNGEQRLFVPRSGFPDLLVDTLLATEDRHFYTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPRGISPQPAFMQLVRQELQAKLVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQS 5hlb A 2.42 BS01 M0E A 1 E233 V262 G264 Q271 K274 N275 R286 Y315 Q318 E323 V354 K355 G356 A357 S358 I359 E167 V196 G198 Q205 K208 N209 R220 Y249 Q252 E257 V288 K289 G290 A291 S292 I293 2.4.1.129,3.4.-.- P02919 27899450 WLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSEM 5hlb A 2.42 BS02 AZR A 1 S507 S510 D553 N574 L611 G612 T682 T699 G700 T701 T702 N703 S441 S444 D487 N508 L545 G546 T616 T633 G634 T635 T636 N637 2.4.1.129,3.4.-.- P02919 27899450 WLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSEM 5hld A 2.31 BS01 63V A 1 S510 K513 D553 N574 T682 T699 T701 T702 N703 S361 K364 D404 N425 T533 T550 T552 T553 N554 2.4.1.129,3.4.-.- 27899450 AIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATETQQLVKNLFLSKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVLALERRNLVLRLLYDMLSARPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSE 5hld A 2.31 BS02 M0E A 1 E233 Q271 K274 N275 Y315 E323 V354 E161 Q164 K167 N168 Y201 E209 V240 2.4.1.129,3.4.-.- 27899450 AIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATETQQLVKNLFLSKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVLALERRNLVLRLLYDMLSARPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSE 5hot A 4.40 BS01 2SQ A 1 Q168 A169 E170 H171 T174 M178 Q107 A108 E109 H110 T113 M117 2.7.7.- CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQM 5hot A 4.40 BS02 2SQ B 1 Q95 A98 T124 T125 A128 A129 W132 Q40 A43 T69 T70 A73 A74 W77 2.7.7.- CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQM 5hot B 4.40 BS01 2SQ A 1 A98 L102 T124 T125 A129 W132 A43 L47 T69 T70 A74 W77 2.7.7.- Q72498 CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQENPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMA 5hot B 4.40 BS02 2SQ B 1 A169 E170 H171 T174 M178 A109 E110 H111 T114 M118 2.7.7.- Q72498 CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQENPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMA 5hwk A 1.34 BS01 BEZ A 1 G12 Y13 G14 S15 L16 L111 R114 E115 Y119 Y161 G7 Y8 G9 S10 L11 L106 R109 E110 Y114 Y156 2.3.2.- P32656 27913623 SGIWVLGYGSLIYKPPSHYTHRIPAIIHGFARRFWQSSTDHRGTPANPGRVATLIPYEDIIRQTAFLKNVNLYSESAPIQDPDDLVTIGVVYYIPPEHAQEVREYLNVREQNGYTLHEVEVHLETNREHEAELGEALEQLPRHNKSGKRVLLTSVYIGTIDNEAFVGPETVDETAKVIAVSHGPSGSNYEYLAKLEQALAQMPIRITDHYLTALLETVNKYRH 5hz6 A 1.14 BS01 65Y A 1 F17 M21 V26 T30 A34 A37 P39 S54 E55 S56 F58 K59 T61 A76 D77 I105 R107 C118 R127 F16 M20 V25 T29 A33 A36 P38 S53 E54 S55 F57 K58 T60 A75 D76 I104 R106 C117 R126 P15090 27658368 AGAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA 5hz8 A 1.12 BS01 65Z A 1 F17 Y20 M21 L24 T30 A34 A37 S56 F58 A76 D77 R79 R107 L116 L118 R127 Y129 F20 Y23 M24 L27 T33 A37 A40 S59 F61 A79 D80 R82 R110 L119 L121 R130 Y132 P15090 27658368 GSHMCDAFVGTWKLVSSENFDDYMKELGVGFATRKVAGMAKPNTIISVNGDVITLKTESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTLKRKREDDKLVLELVMKGVTCTRVYERA 5hz9 A 2.30 BS01 5M8 A 1 F17 M21 P39 T54 S56 F58 A76 D77 L105 Y129 F19 M23 P41 T56 S58 F60 A78 D79 L107 Y131 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 A 2.30 BS02 5M8 A 2 K22 G27 F28 R31 K24 G29 F30 R33 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 B 2.30 BS02 5M8 B 2 G25 G27 F28 R31 G27 G29 F30 R33 P05413 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 C 2.30 BS01 5M8 C 1 F17 M21 T37 T54 S56 F58 K59 A76 D77 L105 F19 M23 T39 T56 S58 F60 K61 A78 D79 L107 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 C 2.30 BS02 5M8 C 2 V26 G27 F28 R31 V28 G29 F30 R33 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 D 2.30 BS01 5M8 D 1 F17 M21 T37 T54 S56 F58 A76 D77 L105 F19 M23 T39 T56 S58 F60 A78 D79 L107 P05413 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 E 2.30 BS01 5M8 E 1 M21 T30 T54 S56 F58 K59 A76 D77 L105 L118 M23 T32 T56 S58 F60 K61 A78 D79 L107 L120 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 E 2.30 BS02 5M8 E 2 V33 M36 T57 F58 V35 M38 T59 F60 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 F 2.30 BS01 5M8 F 1 F17 M21 A34 T54 S56 F58 A76 D77 L105 F18 M22 A35 T55 S57 F59 A77 D78 L106 P05413 27658368 HMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 G 2.30 BS01 5M8 G 1 F17 M21 V26 T30 A34 T54 S56 F58 K59 A76 D77 L105 F19 M23 V28 T32 A36 T56 S58 F60 K61 A78 D79 L107 P05413 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 G 2.30 BS02 5M8 G 2 F58 K59 D78 F60 K61 D80 P05413 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 H 2.30 BS01 5M8 H 1 F17 M21 T54 S56 F58 A76 D77 L105 F19 M23 T56 S58 F60 A78 D79 L107 P05413 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5hz9 H 2.30 BS02 5M8 H 2 A29 T30 F58 K59 A76 D78 A31 T32 F60 K61 A78 D80 P05413 27658368 SHMVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 5i0b A 3.09 BS01 67U A 1 I327 A348 K350 M395 E396 L398 E399 G401 A402 L447 I27 A48 K50 M95 E96 L98 E99 G101 A102 L147 2.7.11.1 27117431 HEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNR 5i0d A 1.77 BS08 GLC A 6 A442 T443 Y496 A411 T412 Y465 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d A 1.77 BS10 GLC A 8 E428 K563 D565 R614 W627 D630 F663 H689 E397 K532 D534 R583 W596 D599 F632 H658 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d A 1.77 BS12 GLC A 10 T664 G665 K692 T633 G634 K661 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d A 1.77 BS13 GLC A 11 Y303 E691 Y272 E660 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d A 1.77 BS14 GLC A 12 Q429 E433 K490 S693 Q398 E402 K459 S662 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d B 1.77 BS06 GLC B 4 A442 T443 A411 T412 Q8Y4J2 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d B 1.77 BS10 GLC B 8 Y303 E691 K692 Y272 E660 K661 Q8Y4J2 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d B 1.77 BS13 GLC B 11 D78 W80 G130 D47 W49 G99 Q8Y4J2 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d B 1.77 BS14 GLC B 12 D78 T94 D47 T63 Q8Y4J2 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0d B 1.77 BS15 GLC B 13 W80 E82 N92 W49 E51 N61 Q8Y4J2 MDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK 5i0e B 2.30 BS01 GLC B 1 N302 E330 A331 E335 F338 W430 N273 E301 A302 E306 F309 W401 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEAKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0e B 2.30 BS02 GLC B 2 N302 E330 W430 K465 D467 R516 W529 D532 F565 H591 N273 E301 W401 K436 D438 R487 W500 D503 F536 H562 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEAKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0f B 1.85 BS01 GLC B 1 H78 E198 Y200 W429 W430 R516 D532 F565 E593 H78 E198 Y200 W426 W427 R513 D529 F562 E590 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0f B 1.85 BS02 GLC B 2 H78 E593 F594 H78 E590 F591 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0f B 1.85 BS04 BGC B 1 E330 W387 W430 K465 D467 R516 W529 D532 F565 H591 E327 W384 W427 K462 D464 R513 W526 D529 F562 H588 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0f B 1.85 BS05 CA B 1 N349 D358 N346 D355 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0f B 1.85 BS06 CA B 2 E76 L79 E76 L79 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0f B 1.85 BS07 CA B 3 D253 L254 G255 D486 D253 L254 G255 D483 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0g B 2.15 BS01 GLC B 1 H78 E198 W429 W430 R516 E593 H78 E198 W427 W428 R514 E591 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGAEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0g B 2.15 BS02 GLC B 2 N302 E330 A331 E335 F431 N300 E328 A329 E333 F429 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGAEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0g B 2.15 BS03 GLC B 3 E330 W387 W430 K465 D467 R516 F565 H591 E328 W385 W428 K463 D465 R514 F563 H589 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGTDSDAALLAGGEGHLAAAQQAALDADNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGAEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVGAA 5i0r A 1.35 BS02 DCY A 1 Y58 L75 S83 H86 H88 L95 H140 H155 Y157 Y54 L71 S79 H82 H84 L91 H136 H151 Y153 1.13.11.20 P21816 27477048 ELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTP 5i0s A 1.30 BS02 THJ A 1 R60 H86 H88 H140 H155 Y157 R56 H82 H84 H136 H151 Y153 1.13.11.20 27477048 ELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTP 5idk A 1.50 BS01 6A8 A 1 D82 G83 N84 A1036 H1051 D1129 Y1130 T1132 G1133 T1134 S1135 G1151 N1152 G1153 I1155 Y1161 D32 G33 N34 A71 H86 D164 Y165 T167 G168 T169 S170 G186 N187 G188 I190 Y196 3.4.21.91,3.6.1.15,3.6.4.13,2.1.1.56,2.1.1.57,2.7.7.48 P06935 DMWIERTADITWESDAEITGSSERVDVRLDDDGNFQLMGGVLWDTPSPKKGDTTTGVYRIMTRGLLGSYQAGAGVMVEGVFHTLWHTTKGAALMSGEGRLDPYWGSVKEDRLCYGGPWKLQHKWNGHDEVQMIVVEPGKNVKNVQTKPGVFKTPEGEIGAVTLDYPTGTSGSPIVDKNGDVIGLYGNGVIMPNGSYISAIVQGE 5jm1 C 1.95 BS02 III D 1 A8 T72 F104 L106 D125 Y126 F127 S128 M129 Y130 L131 A8 T72 F104 L106 D125 Y126 F127 S128 M129 Y130 L131 P18670 27808459 GKAFDDGAFTGIREINLSYNKETAIGDFQVVYDLNGSPYVGQNHKSFITGFTPVKISLDFPSEYIMEVSGYTGNVSGYVVVRSLTFKTNKKTYGPYGVTSGTPFNLPIENGLIVGFKGSIGYWLDYFSMYLSL 5jm1 E 1.95 BS05 GAL E 2 S76 Y122 W123 S76 Y122 W123 P18670 27808459 GKAFDDGAFTGIREINLSYNKETAIGDFQVVYDLNGSPYVGQNHKSFITGFTPVKISLDFPSEYIMEVSGYTGNVSGYVVVRSLTFKTNKKTYGPYGVTSGTPFNLPIENGLIVGFKGSIGYWLDYFSMYLSL 5k3w A 2.50 BS01 PLP A 1 H72 R75 K174 Y178 E207 P209 T210 S211 N212 L231 T234 T235 S270 S271 H62 R65 K164 Y168 E197 P199 T200 S201 N202 L221 T224 T225 S260 S261 27905516 TRATLLTVTAPTRPRAAGDAGFVLADFGAPQVRITDLGITRGDGVFETIAVIDGHPQALELHLGRLAHSAALLDLPEPDAAVWREAVLAGVADYRSRNGDGGELFAKLILTRGIEGEGRPSGWVFVDEGEDFSQQRLGIRVVTLDRGYRHDVAETSPWLLAGAKSLSYATNRAAGREAARRGADDVIFVSSDGYALEGPTSNVIVLADGVVRTPQTDQGILAGTTQAAVFDFFEERGYPTEYRRISADELRDAEALWLVSSVRQAAPITALDDREYPVDAALTADLNAYLLARTDLEH 5koy A 3.85 BS01 ATP A 1 D160 Y397 S399 R400 I405 S425 G426 G428 K429 S430 Q552 D130 Y367 S369 R370 I375 S395 G396 G398 K399 S400 Q522 3.6.3.44 P21447 27864369 PAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDQATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTDVPPASFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDQATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQAG 5koy B 3.85 BS01 ATP B 1 D160 Y397 S399 I405 S425 G426 C427 G428 K429 S430 Q552 R901 D130 Y367 S369 I375 S395 G396 C397 G398 K399 S400 Q522 R811 3.6.3.44 27864369 PAVSVLTMFRYAGWLDRLYMLVGTLAAIIHGVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKELHAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFLLIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYEVFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVALVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTIAENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDQATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKGIYFKLVMTQTDVPPASFWRILKLNSTEWPYFVVGIFCAIINGGLQPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEILTKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLGTGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLVTQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDQATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQA 5kpq A 2.55 BS01 6X2 A 1 D766 L769 H862 G863 R878 Y889 I895 Y896 F897 S904 Y907 E988 D104 L107 H200 G201 R216 Y227 I233 Y234 F235 S242 Y245 E326 2.4.2.30 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5kpq B 2.55 BS01 6X2 B 1 D766 D770 H862 G863 R878 Y889 G894 I895 Y896 F897 S904 Y907 E988 D104 D108 H200 G201 R216 Y227 G232 I233 Y234 F235 S242 Y245 E326 2.4.2.30 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5l57 A 2.70 BS01 NDP A 1 T75 I76 T77 R82 N96 D279 S280 L288 E306 H309 G310 T311 V312 T313 R314 H315 N328 T73 I74 T75 R80 N94 D274 S275 L283 E301 H304 G305 T306 V307 T308 R309 H310 N323 1.1.1.42 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDAARVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAYGDQYRATDFVVPGPGKVEITYTPSDGTTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFAAAAIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 5l57 A 2.70 BS02 6N3 A 1 A111 R119 W124 I130 V255 Y285 A109 R117 W122 I128 V250 Y280 1.1.1.42 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDAARVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAYGDQYRATDFVVPGPGKVEITYTPSDGTTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFAAAAIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 5l58 A 3.04 BS01 NDP A 1 K72 T75 T77 N96 L288 G289 E306 H309 G310 T311 V312 T313 R314 H315 N328 D375 K70 T73 T75 N94 L250 G251 E268 H271 G272 T273 V274 T275 R276 H277 N290 D337 1.1.1.42 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDAARVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAYGATDFVVPGPEITTYLVGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKKYDGRFKDIFQEIYDKQYKSQFAAAAIWYEHRLIDDMVAQAMKSEGGFIWACKNYVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 5l58 A 3.04 BS02 6MX A 1 A111 R119 W124 I130 I251 V255 W267 N271 Y285 A109 R117 W122 I128 I221 V225 W237 N241 Y247 1.1.1.42 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDAARVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHAYGATDFVVPGPEITTYLVGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKKYDGRFKDIFQEIYDKQYKSQFAAAAIWYEHRLIDDMVAQAMKSEGGFIWACKNYVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 5lf5 A 3.80 BS01 FUC A 1 T330 S348 T311 S329 27922006 GHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSNPEPSVAFELPSTVNETEREFVYSERSGLLLTSILTIRGQAQAPPRVICTSRNLYGTQSLELPFQGA 5lf5 A 3.80 BS02 GAL A 1 P66 K67 P47 K48 27922006 GHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSNPEPSVAFELPSTVNETEREFVYSERSGLLLTSILTIRGQAQAPPRVICTSRNLYGTQSLELPFQGA 5lf5 A 3.80 BS03 SIA A 1 Y65 R118 Y124 Q126 Y127 T128 Y46 R99 Y105 Q107 Y108 T109 27922006 GHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSNPEPSVAFELPSTVNETEREFVYSERSGLLLTSILTIRGQAQAPPRVICTSRNLYGTQSLELPFQGA 5lfv B 2.30 BS01 SIA B 1 W22 Y65 R118 Y124 Q126 Y127 T128 W4 Y47 R100 Y106 Q108 Y109 T110 P20917 27922006 SGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAAAAH 5lfv B 2.30 BS02 GAL B 1 Y65 P66 K67 Y47 P48 K49 P20917 27922006 SGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAAAAH 5lkr A 2.52 BS02 6YC A 1 N68 I69 D70 G117 T120 S198 W231 F329 N66 I67 D68 G115 T118 S196 W229 F327 3.1.1.8 27908752 DIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 5lkr B 2.52 BS02 6YC B 1 N68 D70 G117 T120 S198 W231 F329 Y332 N65 D67 G114 T117 S195 W228 F326 Y329 3.1.1.8 27908752 IIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 5lxy M 2.85 BS01 III N 1 E28 Q32 Y76 E20 Q24 Y57 Q9Y580 27905398 EADRTLFVGNLTKVTELLFELFHQAGPVIKVQFAFVNFKHEVSVPYAMNLLNGIKLYPIKIQFR 5lxy M 2.85 BS02 III N 2 L29 H31 Q32 A33 G34 P35 H59 V61 Y65 L70 L21 H23 Q24 A25 G26 P27 H40 V42 Y46 L51 Q9Y580 27905398 EADRTLFVGNLTKVTELLFELFHQAGPVIKVQFAFVNFKHEVSVPYAMNLLNGIKLYPIKIQFR 5lz6 A 2.60 BS01 BGC A 1 D426 R484 Y512 S513 K518 D61 R82 Y110 S111 K116 Q9H3P7 LPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR 5lzq A 3.50 BS02 MG A 2 E217 D218 D228 D465 E216 D217 D227 D464 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq A 3.50 BS05 MG A 5 D488 N492 D660 D487 N491 D659 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq A 3.50 BS06 2PN A 1 K199 D202 E217 D232 D465 N492 D660 D692 K198 D201 E216 D231 D464 N491 D659 D691 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq A 3.50 BS07 NA A 1 D243 E246 S247 D703 I704 K707 D242 E245 S246 D702 I703 K706 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq A 3.50 BS08 2PN A 2 K269 E272 K268 E271 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq A 3.50 BS09 2PN A 3 L533 V534 L536 L532 V533 L535 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq B 3.50 BS01 MG B 1 K199 D202 D688 D692 K198 D201 D687 D691 3.6.1.1 Q9S5X0 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzq B 3.50 BS06 2PN B 1 D202 E217 D465 D488 N492 D660 K663 D692 K695 D201 E216 D464 D487 N491 D659 K662 D691 K694 3.6.1.1 Q9S5X0 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQAREIPGLLEGKAKPDYNRCIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5lzr B 4.00 BS01 MG B 1 D465 N492 D451 N478 3.6.1.1 27922000 YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLAHETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRANVRVAEAARTTKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKWMGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAADMAADLVRNPATIADNVGDNVGDVAGLGADLLESFVGAIVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCSMLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLDVLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSIEGTGMVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVATSVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAIGSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAAITYYFSGYLISAVTKAAMKMVDEIRRQARECIEITSDNALKQMGYPAFIAILTPLVTGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGYGKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVHLF 5m93 B 1.79 BS01 RIB B 1 D39 R42 R72 D43 R46 R76 P0CG47 27912065 GPLGSQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRL 5m96 A 1.77 BS01 Q6Y A 1 L287 C320 H323 L324 M365 A368 V376 F377 F378 F388 L391 L396 I400 F401 S404 H479 R482 F486 L23 C56 H59 L60 M101 A104 V112 F113 F114 F124 L127 L132 I136 F137 S140 H215 R218 F222 27902884 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHL 5m96 A 1.77 BS02 Q6Y A 2 T325 I328 Q329 E333 K336 K354 A357 M358 V480 T61 I64 Q65 E69 K72 K90 A93 M94 V216 27902884 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHL 5m96 B 1.77 BS01 Q6Y B 1 L287 C320 H323 L324 M365 A368 V376 F377 F378 F388 L391 L396 I397 I400 F401 S404 H479 F486 L23 C56 H59 L60 M101 A104 V112 F113 F114 F124 L127 L132 I133 I136 F137 S140 H215 F222 P51449 27902884 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQ 5m96 B 1.77 BS02 Q6Y B 2 V332 Q346 I350 L353 K354 V68 Q82 I86 L89 K90 P51449 27902884 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLSKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQ 5mdn A 2.80 BS01 MG A 1 D7 S269 D363 D7 S269 D363 2.7.7.7 A3MV07 MRFWPLDATYSVVGGVPEVRVFGVDGEGRRVVLVDRRFRPYFYAKCDKCDASLAKSYLSRVAPVEAVEVVERRFFGRPTIFLKVVAKVPEDVRKLREAALGAPGVVDVYEADIRYYMRYMIDKGVVPCAWNVVEAREAGKLGPLPLYEVVEWAGVEEGFPPPLRVLAFDIEVYNERGSPDPLRDPVVMLAVKTSDGREEVFEAEGRDDRRVIRGFVDFVKEFDPDVIVGYNSNGFDWPYLSERAKALGVPLRVDRLGGVPQQSVYGHWSVVGRANVDLYNIVDEFPEIKVKTLDRVAEYFGVMKRSERVLIPGHKVYEYWNDPAKRPTLMRYVLDDVRSTLGLAEKLLPFLIQLSSVSGLPLDQVAAASVGNRVEWMLLRYAYRMGEVAPNREEREYEPYKGAIVLEPKPGLYSDVLVLDFSSMYPNIMMKYNLSPDTYLEPHEPDPPEGVVVAPEVGHRFRKAPTGFIPAVLKHLVELRRAVREEAKKYPPDSPEYRLLDERQRALKVMANAMYGYLGWVGARWYKKEVAESVTAFARAILLDVVEYAKRLGIEVIYGDTDSLFVKKSGAVDRLVKYVEERHGIEIKVDKDYERVLFTEAKKRYAGLLRDGRIDIVGFDWCELAKEVQLNVVELILKSKSVGEARERVVKYVREVVERLKAYKFDLDDLIIWKTLDKELDEYKAYGPHVHAALELKRRGYKVGKGTTVGYVIVRGPGKVSERAMPYIFVDDASKVDVDYYIEKQVIPAALRIAEVLGVKE 5mgy H 2.60 BS01 MG H 1 S183 D297 T301 S155 D265 T269 2.7.1.180 27864152 MDLFQDKVEAFTGPTMGSTYTVKYVRSGDGPAKEVLHGEVEAILGQLDKQLSTYRSDSDVERFNALPAGSCEPMPDMVRELVAAGSQLSADSDGAFDLTLEPLLNLWGFGPQGRGERVPSAEDISAARALTGQQHLSIDGDRLCKAVALQLDFNSIAAGYAVDLVIDRLKALGVQSYLVEITGELKAEGRKPDGSPWRIAIEAPRVAQKIVELDGMGVSTSGDYRNYFERDGRRYSHTLDPQSGQPIEHHLAAVTVIDKSTLRADGLSTALMVLGPEKGLALAERNGIAAFFVVREGQGFVTTSTKAFDELFGAGV 5mgy E 2.60 BS01 MG E 1 D297 S300 T301 D265 S268 T269 2.7.1.180 27864152 MDLFQDKVEAFTGPTMGSTYTVKYVRSGDGPAKEVLHGEVEAILGQLDKQLSTYRSDSDVERFNALPAGSCEPMPDMVRELVAAGSQLSADSDGAFDLTLEPLLNLWGFGPQGRGERVPSAEDISAARALTGQQHLSIDGDRLCKAVALQLDFNSIAAGYAVDLVIDRLKALGVQSYLVEITGELKAEGRKPDGSPWRIAIEAPRVAQKIVELDGMGVSTSGDYRNYFERDGRRYSHTLDPQSGQPIEHHLAAVTVIDKSTLRADGLSTALMVLGPEKGLALAERNGIAAFFVVREGQGFVTTSTKAFDELFGAGV 5mkg A 2.44 BS04 C2E A 1 Q25 E39 L41 M42 R43 R53 P54 D55 I58 L74 N98 S100 D160 D161 Q184 G218 E220 G238 Y239 Q21 E35 L37 M38 R39 R49 P50 D51 I54 L70 N94 S96 D156 D157 Q172 G206 E208 G226 Y227 ASPSSELRRALEANEFIPYYQPLSPGQGGRWIGVEVLMRWRHPREGLIRPDLFIPFAERSGLIVPMTRALMRQVAEDLGGHAGKLEPGFHIGFNISATHCHELALVDDCRELLAAFPPGHITLVLELTERELIESSEVTDRLFDELHALGVKIAIDDFGTRKFQVDCLKIDQSFVARIGIDTLSGHILDSIVELSAKLDLDIVAEGVETPEQRDYLAARGVDYLQGYLIGRPMPLESLLSSLTVQEGQ 5svi A 1.61 BS01 III C 1 S0 D407 Q408 T409 W410 V411 Q412 W419 D424 L429 P430 E431 W433 E453 S1 D2 Q3 T4 W5 V6 Q7 W14 D19 L22 P23 E24 W26 E46 27653685 SDQTWVQCDACLKWRKLPDGMLPEKWYCSNNPDPQFRNCEVPEEPE 5svi B 1.61 BS01 III D 1 P-3 L-2 S0 D1 Q2 T3 W4 V5 Q6 W13 D18 L23 P24 E25 W27 E47 P2 L3 S5 D6 Q7 T8 W9 V10 Q11 W18 D23 L28 P29 E30 W32 E52 A0A0P6K566 27653685 GPLGSDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPED 5swi B 2.15 BS01 CA B 1 N557 Q558 D600 N556 Q557 D599 A0A0Y0HIE3 KPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSDQDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDKACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKRTLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFISPSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTFYEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADPLGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAEQLTFTLSWLPSH 5swi B 2.15 BS02 BMA B 1 W70 E489 H540 E541 W69 E488 H539 E540 A0A0Y0HIE3 KPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSDQDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDKACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKRTLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFISPSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTFYEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADPLGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAEQLTFTLSWLPSH 5swi A 2.15 BS02 CA A 1 N557 Q558 D598 D600 N556 Q557 D597 D599 A0A0Y0HIE3 KPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSDQDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDKACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKRTLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFISPSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTFYEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADPLGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAEQLTFTLSWLPS 5swi C 2.15 BS01 BMA C 1 W70 H540 E541 W69 H527 E528 KPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSDQDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDKACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKRTLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFISPSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTFYEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAASQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQLMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYLFRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAEQLTFTLSWLPS 5szt A 1.80 BS02 NUC C 1 N483 N485 S486 Q489 I503 G504 S513 S515 A517 V518 S543 T544 T569 A570 T571 R573 S575 S576 S577 D578 N580 T664 G668 Y671 G672 M673 S674 R677 Q680 R728 R746 M747 N750 Q754 N191 N193 S194 Q197 I211 G212 S221 S223 A225 V226 S251 T252 T277 A278 T279 R281 S283 S284 S285 D286 N288 T372 G376 Y379 G380 M381 S382 R385 Q388 R436 R454 M455 N458 Q462 2.7.7.7 P19821 27901305 ALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 5szt A 1.80 BS05 72J A 1 R573 R587 D610 Y611 S612 Q613 I614 E615 H639 R659 R660 A661 K663 T664 F667 D785 R281 R295 D318 Y319 S320 Q321 I322 E323 H347 R367 R368 A369 K371 T372 F375 D493 2.7.7.7 P19821 27901305 ALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 5t1a A 2.81 BS01 73R A 1 V37 G41 L44 L45 Y49 W98 T117 Y120 C190 Q288 V289 E291 T292 M295 V1 G5 L8 L9 Y13 W62 T81 Y84 C154 Q413 V414 E416 T417 M420 3.2.1.17 27926736 VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRINIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF 5t1a A 2.81 BS02 VT5 A 1 V63 T77 L81 R237 A241 V244 Y305 G309 E310 K311 F312 V27 T41 L45 R362 A366 V369 Y430 G434 E435 K436 F437 3.2.1.17 27926736 VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRINIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF 5t1a A 2.81 BS03 ZN A 1 H144 E1005 E238 H108 E201 E363 3.2.1.17 27926736 VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGISRASKSRINIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF 5t3r A 3.10 BS01 MG A 1 E262 Y273 S399 N401 E262 Y273 S399 N401 CDDFLDRQVPQGIVTGDQIASPEYVDNLVISAYAIWATGDDINSSFSLWNYDVRSDDCYKGGSGTEDGGVFNALEISKGINTTDWNINDIWKRLYQCITRANTALQSLDQMDEKTYPLKNQRIAEMRFLRGHAHFMLKQLFKKIVIVNDENMEPDAYNELSNTTYTNDEQWQKIADDFQFAYDNLPEVQIEKGRPAQAAAAAYLAKTYLYKAYRQDGADNALTGINEEDLKQVVKYTDPLIMAKGGYGLETDYSMNFLPQYENGAESVWAIQYSINDGTYNGNLNWGMGLTTPQILGCCDFHKPSQNLVNAFKTDSQGKPLFSTYDNENYEVATDNVDPRLFHTVGMPGFPYKYNEGYIIQKNDDWSRSKGLYGYYVSLKENVDPDCDCLKKGSYWASSLNHIVIRYADVLLMRAEALIQLNDGRITDAISLINEVRSRAAGSTMLIFNYKEDYGVNFKVTPYDLKAYAQDEAMKMLKWERRVEFGMESSRFFDLVRWGEAKDVINAYYVTEASRCSIYKNAGFTENKNEYLPVPFEQISASNGNYTQNFGWH 5t3r D 3.10 BS01 MG D 1 D837 D839 N841 V843 I844 D848 D627 D629 N631 V633 I634 D638 Q8A6W3 QIKINFDASVSASMYQSKMNVLNTEQYGRAMWQAYVNDGENPNGNALGYAYNWGYNADGNPVLYGMTLSKYLDSKNTMPVADTDWFDEITRTGVIQQYNLSVSNGSEKGSSFFSLGYYKNLGVIKDTDFDRFSARMNSDYKLIDDILTIGQHFTLNRTSEVQAPGGIIETALDIPSAIPVYASDGSWGGPVGGWPDRRNPRAVLEYNKDNRYTYWRMFGDAYVNLTPFKGFNLRSTFGLDYANKQARYFTYPYQEGTQTNNGKSAVEAKQEHWTKWMWNAIATYQLEVGKHRGDVMIGMELNREDDSHFSGYKEDFSILTPDYMWPDAGSGTAQAYGAGEGYSLVSFFGKMNYSYADRYLLSLTLRRDGSSRFGKNHRYATFPSVSLGWRITQENFMKELTWLDDLKLRASWGQTGNQEISNLARYTIYAPNYGTTDSFGGQSYGTAYDITGSNGGGVLPSGFKRNQIGNDNIKWETTTQTNVGIDFSLFKQSLYGSLEYYYKKATDILTEMAGVGVLGEGGSRWINSGAMKNQGFEFNLGYRNKTAFGLTYDLNGNISTYRNEILELPETVAANGKFGGNGVKSVVGHTYGAQVGYIADGIFKSQDEVDNHATQEGAAVGRIRYRDIDHNGVIDERDQNWIYDPTPSFSYGLNIYLEYKNFDLTMFWQGVQGVDIISDVKKKSDFWSASNVGFLNKGTRLLNAWSPTNPNSDIPALTRSDTNNEQRVSTYFVENGSFLKLRNIQLGYTVPAVISKKMRMDRLRFYCSAQNLLTIKSKNFTGEDPENPNFSYPIPVNITFGLNIGF 5t4y A 3.10 BS02 MG A 2 V53 R54 S55 C58 E75 Y508 Y519 V53 R54 S55 C58 E75 Y508 Y519 CDDFLDRQVPQGIVTGDQIASPEYVDNLVISAYAIWATGDDINSSFSLWNYDVRSDDCYKGGSGTEDGGVFNALEISKGINTTDWNINDIWKRLYQCITRANTALQSLDQMDEKTYPLKNQRIAEMRFLRGHAHFMLKQLFKKIVIVNDENMEPDAYNELSNTTYTNDEQWQKIADDFQFAYDNLPEVQIEKGRPAQAAAAAYLAKTYLYKAYRQDGADNALTGINEEDLKQVVKYTDPLIMAKGGYGLETDYSMNFLPQYENGAESVWAIQYSINDGTYNGNLNWGMGLTTPQILGCCDFHKPSQNLVNAFKTDSQGKPLFSTYDNENYEVATDNVDPRLFHTVGMPGFPYKYNEGYIIQKNDDWSRSKGLYGYYVSLKENVDPDCDCLKKGSYWASSLNHIVIRYADVLLMRAEALIQLNDGRITDAISLINEVRSRAAGSTMLIFNYKEDYGVNFKVTPYDLKAYAQDEAMKMLKWERRVEFGMESSRFFDLVRWGEAKDVINAYYVTEASRCSIYKNAGFTENKNEYLPVPFEQISASNGNYTQNFGW 5t4y C 3.10 BS01 MG C 1 D837 D839 N841 V843 I844 D845 D848 D628 D630 N632 V634 I635 D636 D639 GQIKINFDASVSASMYQSKMNVLNTEQYGRAMWQAYVNDGENPNGNALGYAYNWGYNADGNPVLYGMTLSKYLDSKNTMPVADTDWFDEITRTGVIQQYNLSVSNGSEKGSSFFSLGYYKNLGVIKDTDFDRFSARMNSDYKLIDDILTIGQHFTLNRTSEVQAPGGIIETALDIPSAIPVYASDGSWGGPVGGWPDRRNPRAVLEYNKDNRYTYWRMFGDAYVNLTPFKGFNLRSTFGLDYANKQARYFTYPYQEGTQTNNGKSAVEAKQEHWTKWMWNAIATYQLEVGKHRGDVMIGMELNREDDSHFSGYKEDFSILTPDYMWPDAGSGTAQAYGAGEGYSLVSFFGKMNYSYADRYLLSLTLRRDGSSRFGKNHRYATFPSVSLGWRITQENFMKELTWLDDLKLRASWGQTGNQEISNLARYTIYAPNYGTTDSFGGQSYGTAYDITGSNGGGVLPSGFKRNQIGNDNIKWETTTQTNVGIDFSLFKQSLYGSLEYYYKKATDILTEMAGVGVLGEGGSRWINSGAMKNQGFEFNLGYRNKTAFGLTYDLNGNISTYRNEILELPETVAANGKFGGNGVKSVVGHTYGAQVGYIADGIFKSQDEVDNHATQEGAAVGRIRYRDIDHNGVIDERDQNWIYDPTPSFSYGLNIYLEYKNFDLTMFWQGVQGVDIISDVKKKSDFWSASNVGFLNKGTRLLNAWSPTNPNSDIPALTRSDTNNEQRVSTYFVENGSFLKLRNIQLGYTVPAVISKKMRMDRLRFYCSAQNLLTIKSKNFTGEDPENPNFSYPIPVNITFGLNIGF 5t7b A 2.53 BS01 NUC R 1 S220 A221 H271 F294 L296 Y311 F312 H316 K335 H336 T337 Y338 L339 R351 I353 T361 M364 I365 T368 G524 K525 T526 Y529 K533 Q545 C546 V547 Q548 N551 T559 N562 L563 K566 K570 P602 R635 K709 R710 R714 H753 I756 Q757 T759 S760 R761 Y790 R792 C793 R795 S798 Y804 S189 A190 H237 F257 L259 Y274 F275 H279 K298 H299 T300 Y301 L302 R314 I316 T324 M327 I328 T331 G487 K488 T489 Y492 K496 Q508 C509 V510 Q511 N514 T522 N525 L526 K529 K533 P565 R594 K668 R669 R673 H712 I715 Q716 T718 S719 R720 Y749 R751 C752 R754 S757 Y763 3.1.26.- Q9UKV8 FKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEKPLTDSQRVKFTKEIKGLKVEITHCKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGANVTHPPKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRNGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKRDHQALAKAVQVHQDTLRTMYFA 5tc4 A 1.89 BS01 NAD A 1 T176 G200 R201 S202 N204 V205 H232 R233 A253 A254 G255 I256 V274 G275 I276 G313 T316 T141 G165 R166 S167 N169 V170 H197 R198 A218 A219 G220 I221 V239 G240 I241 G273 T276 1.5.1.15,3.5.4.9 27899380 EAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVL 5tc4 A 1.89 BS02 L34 A 1 Y84 N87 K88 V131 Q132 L133 D155 F157 I276 R278 L289 P309 G310 G313 P314 T316 V317 Y49 N52 K53 V96 Q97 L98 D120 F122 I241 R243 L249 P269 G270 G273 P274 T276 V277 1.5.1.15,3.5.4.9 27899380 EAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVL 5tj6 A 3.40 BS01 MG A 1 E363 T385 E388 E307 T329 E332 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS02 CA A 1 D356 R503 S504 G523 E525 E591 D300 R447 S448 G467 E469 E530 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS03 CA A 2 Q899 D902 D905 D907 Q729 D732 D735 D737 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS04 PGW A 1 A112 T137 T138 A65 T81 T82 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS05 PGW A 2 W16 W192 S248 W3 W136 S192 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS06 PGW A 3 I299 F300 I243 F244 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS07 PGW A 4 T291 I295 T235 I239 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS08 PGW A 5 W264 E265 W208 E209 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS09 PGW A 6 I119 T123 I72 T76 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tj6 A 3.40 BS10 PGW A 7 L170 M204 L234 L114 M148 L178 RQWYSFLASSLVTFGSGLVVIIIYRIVLWLCGWMTEAKDWAGELISGQTTTGRILVGLVFLLSIASLIIYFIDASTNSSSTTQQVDLAFNVFFMIYFFIRFVAANDKLWFWVELFSFVDYFTIPPSFVAIYLDRNWLGLRFLRALRLMSIPDILTYLNVLKTSTLIRLVQLVVSFVSLWLTAAGFLHLLENSGDPFFDFGNAQHLTYWECLYFLMVTMSTVGFGDIFATTVLGRTFVVIFIMIFIGLFASFIPEIAEILGKRQKYGGSYKKERGKRHVVVCGYITFDSVSNFLKDFLHKDREDVDVEIVFLHKGLPGLELEGLLKRHFTQVEYFWGSVMDANDLERVKIQEADACLVLANKYCQDPDQEDAANIMRVISIKNYHSDIKVIVQLLQYHNKAYLLNIPSWDWKRGDDAVCVAELKLGFIAQSCLAPGFSTLMANLFTMRSYKPTPEMSQWQTDYMRGTGMEMYTEYLSSAFNALTFPEAAELCFSKLKLLLLAIEVRESTLAINPGPKVKIENATQGFFIAESAEEVKRAFYYCKNCHANVSDVRQIKKCKCRKFDSTGMFHWCPDRPLNDCLQDRSQASASGLRNHVVVCLFADAASPLIGLRNLVMPLRASNFHYHELKPTIIVGNLDYLHREWKTLQNFPKLSILPGSPLNRANLRAVNINLCDMCVIVSAKDRNMEDPNLVDKEAILCSLNIKAMTFDDAGANVPLITELANDSNVQFLDQDDDDDPDTELYMTQPFACGTAFAVSVLDSLMSTSYFNDNALTLIRTLITGGATPELEQILAEGAGMRGGYCSPAVLANRDRCRVAQISLFDGPLAQFGQGGHYGELFVYALRHFGILCIGLYRFRDTNPSSKRYVITNPPEDFPLLPTDQVYVLTYK 5tpw B 2.91 BS01 ZN B 1 H44 H128 E266 D282 H11 H78 E216 D232 LNIAVLLGHSHDVTEDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSQTFIPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGYRDFISFIKTTVDNSFVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGLGILTTAASSMLEKFSYIPEAKASCYGTPLHTLHQFMVNVTWDGKDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENQTLSLRH 5tq2 A 3.29 BS01 ZN A 1 H67 H94 D100 H44 H71 D77 Q91977 PKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLQATSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEGKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETEGTLV 5tsq A 1.53 BS01 CA A 1 D10 D15 N39 T126 D241 D9 D14 N38 T125 D240 3.2.2.1 A4H9Q9 PRKIILDCDPGIDDAVAILLAYGNPEIELLAITTVVGNQTLEKVTRNAQLVADVAGIVGVPIAAGCCKPLVRKVRTAPQIHGETGLGTVSYPSEFKTKLDKRHAVHLIIELIMSHEPKSITLVPTGGLTNIAMAARLEPRIVERVKEVVLMGGSCCIGNASPVAEFNIFVDPEAAHIVFNESWDVTMVGLDLTSQALATPEVLQRVKEVRTKPADFILKILEFYTKVYETQRNTYAKVHDPCAVAYVIDPTVMTTNRVPVNIELNGELTAGMTVTDFRYPRPEQCHTQVASKLDFSKYWDLVIDALQRIGDP 5tsq A 1.53 BS02 BDR A 1 D14 D15 N39 H82 T126 M152 N160 E166 F167 N168 H240 D241 D13 D14 N38 H81 T125 M151 N159 E165 F166 N167 H239 D240 3.2.2.1 A4H9Q9 PRKIILDCDPGIDDAVAILLAYGNPEIELLAITTVVGNQTLEKVTRNAQLVADVAGIVGVPIAAGCCKPLVRKVRTAPQIHGETGLGTVSYPSEFKTKLDKRHAVHLIIELIMSHEPKSITLVPTGGLTNIAMAARLEPRIVERVKEVVLMGGSCCIGNASPVAEFNIFVDPEAAHIVFNESWDVTMVGLDLTSQALATPEVLQRVKEVRTKPADFILKILEFYTKVYETQRNTYAKVHDPCAVAYVIDPTVMTTNRVPVNIELNGELTAGMTVTDFRYPRPEQCHTQVASKLDFSKYWDLVIDALQRIGDP 5tti A 2.20 BS01 FAD A 1 I8 G9 G11 P12 S13 E32 R33 Q34 R42 R44 A45 Q102 C158 D159 G160 G163 I164 Y222 G285 D286 P293 G298 L299 I10 G11 G13 P14 S15 E34 R35 Q36 R44 R46 A47 Q104 C160 D161 G162 G165 I166 Y224 G287 D288 P295 G300 L301 1.14.13.2 Q88H28 NAMKTQVAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQGTVDLLREAGVAERMDREGLVHEGVELLVGGRRQRLDLKALTGGKTVMVYGQTEVTRDLMQAREASGAPIIYSAANVQPHELKGEKPYLTFEKDGRVQRIDCDYIAGCDGFHGISRQSIPEGVLKQYERVYPFGWLGLLSDTPPVNHELIYAHHERGFALCSQRSQTRSRYYLQVPLQDRVEEWSDERFWDELKARLPAEVAADLVTGPALEKSIAPLRSLVVEPMQYGHLFLVGDAAHIVPPTGAKGLNLAASDVNYLYRILVKVYHEGRVDLLAQYSPLALRRVWKGERFSWFMTQLLHDFGSHKDAWDQKMQEADREYFLTSPAGLVNIAENYVGLPFEEVA 5tv7 A 2.05 BS01 HGA A 1 V130 D180 I182 G184 P185 A186 T187 V88 D138 I140 G142 P143 A144 T145 LDSFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYASYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSFGSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS 5tv7 B 2.05 BS01 HGA B 1 D180 I182 G184 P185 A186 T187 D138 I140 G142 P143 A144 T145 LDSFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYASYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSFGSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS 5u1o A 2.31 BS01 FAD A 1 G15 G17 S18 G19 I37 E38 A39 G44 T45 C46 V49 G50 C51 K54 G117 F118 A119 A142 V143 G144 Y181 I182 R267 I274 G306 D307 E314 L315 T316 P317 G10 G12 S13 G14 I32 E33 A34 G39 T40 C41 V44 G45 C46 K49 G112 F113 A114 A137 V138 G139 Y176 I177 R262 I269 G301 D302 E309 L310 T311 P312 Q87TK1 ATHFDYICIGGGSGGIASANRAAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWHGAQIAEAMNLYAEDYGFDVDVKGFDWSKLVESRQAYIGRIHQSYDRVLGNNKVNVIKGFAKFVDEKTVEVNGEHYTADHILIAVGGRPTIPNIPGAEYGIDSNGFFDLAEQPKRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLHTHSVPKEVVKEADGSLTLHLENGESQNVDQLIWAIGRHPATDAINLASTGVATNEKGYIKVDEYQETNVKGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKPNAKMDYDLVPTVVFSHPPIGTIGLTTQEAEEKYGKDNIKVYTSGFTAMYTAVTKHRQPCKMKLVCAGEEETVVGLHGIGFTVDEMIQGFGVAMKMGATKADFDSVVAIHPTGSEEFVTMR 5u1o A 2.31 BS02 FAD B 1 H444 P445 H439 P440 Q87TK1 ATHFDYICIGGGSGGIASANRAAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWHGAQIAEAMNLYAEDYGFDVDVKGFDWSKLVESRQAYIGRIHQSYDRVLGNNKVNVIKGFAKFVDEKTVEVNGEHYTADHILIAVGGRPTIPNIPGAEYGIDSNGFFDLAEQPKRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLHTHSVPKEVVKEADGSLTLHLENGESQNVDQLIWAIGRHPATDAINLASTGVATNEKGYIKVDEYQETNVKGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKPNAKMDYDLVPTVVFSHPPIGTIGLTTQEAEEKYGKDNIKVYTSGFTAMYTAVTKHRQPCKMKLVCAGEEETVVGLHGIGFTVDEMIQGFGVAMKMGATKADFDSVVAIHPTGSEEFVTMR 5u4h A 1.05 BS01 0V5 A 1 M91 R92 C116 I118 R398 M93 R94 C118 I120 R400 2.5.1.7 NAMDKFLITGGVKLEGEVRISGAKNAALPLLAAMILADSPITLTNVPNLKDVNTLVKLIGGLGVTISYENDTVKADTSTLDNQFAPYELVKTMRASILVLGPLLARYGNAKVSLPGGCAIGSRPVDQHLKALEALGAHIEVENGYVHATVDGRLKGGEVVFDMVTVGGTENILMAAALADGVTTIRNAAREPEITDLAQMLIKMGAKIEGLDTDTLVVTGVESLHGCEYAVVADRIETGSYLAAAAITGGRVKTTHTDPSLLEAVLDKFEEMGAEVTRGDDWIELDMLGKRPKAVSFRTLPHPEFPTDMQAQIMAVNAIGRGFATISETIFENRFMHVPELSRMGANIQVEGHDAVVTGVEKLQAAPVMATDLRASFSLVLAALVAEGDTLIDRIYHIDRGYEHVEEKLQGLGAKIKRVS 5u4h B 1.05 BS01 0V5 B 1 R92 C116 I118 R398 R94 C118 I120 R400 2.5.1.7 NAMDKFLITGGVKLEGEVRISGAKNAALPLLAAMILADSPITLTNVPNLKDVNTLVKLIGGLGVTISYENDTVKADTSTLDNQFAPYELVKTMRASILVLGPLLARYGNAKVSLPGGCAIGSRPVDQHLKALEALGAHIEVENGYVHATVDGRLKGGEVVFDMVTVGGTENILMAAALADGVTTIRNAAREPEITDLAQMLIKMGAKIEGLDTDTLVVTGVESLHGCEYAVVADRIETGSYLAAAAITGGRVKTTHTDPSLLEAVLDKFEEMGAEVTRGDDWIELDMLGKRPKAVSFRTLPHPEFPTDMQAQIMAVNAIGRGFATISETIFENRFMHVPELSRMGANIQVEGHDAVVTGVEKLQAAPVMATDLRASFSLVLAALVAEGDTLIDRIYHIDRGYEHVEEKLQGLGAKIKRVS 5u4q A 1.50 BS01 NAD A 1 G7 A9 G10 F11 I12 D31 N32 N34 Y37 K42 L59 D60 L61 L82 A83 A84 A86 A101 A124 Y151 K155 F178 F179 T180 V181 R187 G8 A10 G11 F12 I13 D32 N33 N35 Y38 K43 L60 D61 L62 L83 A84 A85 A87 A95 A118 Y145 K149 F172 F173 T174 V175 R181 4.2.1.46 A0A169YGX7 AMKFLVTGAAGFIGFHIAQRLLNEGHNVVGIDNMNDYYDVSLKQARLDRLAYPAFHFQQLDLADREGMAKLFATEQFDRVIHLAAQANPYAYADANLMGYLNILEGCRHTKVKHLVYASSSSVYGLNRKMPFSTEDSVDHPVSLYAATKKANELMAHTYSHLYGIPTTGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIVEAVVRVLDVIPQANADWTVESGSPATSSAPYRVYNIGNSSPVELMDYITALEEALGMEAQKNMMPITSADTQPLYDLVGFKPQTSVKDGVKNFVDWYKDYYQI 5u4q B 1.50 BS01 NAD B 1 G7 G10 F11 I12 D31 N32 N34 Y37 K42 L59 D60 L61 L82 A83 A84 A124 Y151 K155 F178 F179 V181 R187 M190 G8 G11 F12 I13 D32 N33 N35 Y38 K43 L60 D61 L62 L83 A84 A85 A123 Y150 K154 F177 F178 V180 R186 M189 4.2.1.46 AMKFLVTGAAGFIGFHIAQRLLNEGHNVVGIDNMNDYYDVSLKQARLDRLAYPAFHFQQLDLADREGMAKLFATEQFDRVIHLAAQAGVRLENPYAYADANLMGYLNILEGCRHTKVKHLVYASSSSVYGLNRKMPFSTEDSVDHPVSLYAATKKANELMAHTYSHLYGIPTTGLRFFTVYGPWGRPDMALFKFTKAMLEGRDFTYIDDIVEAVVRVLDVIPQANADWTVESGSPATSSAPYRVYNIGNSSPVELMDYITALEEALGMTSADTQPLYDLVGFKPQTSVKDGVKNFVDWYKDYYQ 5wrn B 2.39 BS01 DC B 1 C195 H196 Q214 R215 S216 D218 G222 N226 H256 Y258 C167 H168 Q186 R187 S188 D190 G194 N198 H228 Y230 2.1.1.45 P04818 MPPHGELQYLGQIQHILRCGVRKDTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME 5wrn A 2.39 BS02 DC A 1 R50 C195 H196 Q214 R215 S216 D218 N226 H256 Y258 R26 C171 H172 Q190 R191 S192 D194 N202 H232 Y234 2.1.1.45 P04818 MPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIK 5wrn D 2.39 BS02 DC D 1 C195 H196 R215 S216 D218 G222 N226 H256 Y258 C171 H172 R191 S192 D194 G198 N202 H232 Y234 2.1.1.45 MPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME 5wrn F 2.39 BS02 DC F 1 C195 H196 R215 S216 G217 D218 N226 H256 Y258 C166 H167 R186 S187 G188 D189 N197 H227 Y229 2.1.1.45 P04818 MPPHGELQYLGQIQHILRCGVRKDGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPT