5b57 A 2.80 BS01 DMU A 1 L78 D79 L90 W219 A223 A226 L55 D56 L67 W190 A194 A197 B4EKB4 TSRRFAPFVLAALAILMGAMSVVALCVGAYRIPLAEAWAALSGDPAAQQARAVLLDIRAPRVVLALLVGGGFGATGAAMQALFRNPLADPGLVGVSSGAALGATTLIVLGPASAAALPVAAFAGGLAVAALVYRLAASRGRLALPLLLLAGIAINALVGAAIGLLTFVADDAQLRSLTFWSLGSLGGAQWPTLAAVAPCVALGGVLLVRERDALNALQLGETEALHLGVPVQRLKRRVLVAVALAVGALVSCAGIIGFIGLVAPHCVRLACGPDQRIVLPGAALLGALLTLAADLAARTVAAPADIPLGVLTALLGAPFFLALLWKNRGA 5b57 B 2.80 BS01 DMU B 1 V86 W219 L222 A223 V62 W189 L192 A193 B4EKB4 SRRFAPFVLAALAILMGAMSVVALCVGAYRIPLAEAWAALSGDPAAQQARAVLLDIRAPRVVLALLVGGGFGATGAAMQALFRNPLADPGLVGVSSGAALGATTLIVLGHASAAALPVAAFAGGLAVAALVYRLAASRGRLALPLLLLAGIAINALVGAAIGLLTFVADDAQLRSLTFWSLGSLGGAQWPTLAAVAPCVALGGVLLVRERDALNALQLGETEALHLGVPVQRLKRRVLVAVALAVGALVSCAGIIGFIGLVAPHCVRLACGPDQRIVLPGAALLGALLTLAADLAARTVAAPADIPLGVLTALLGAPFFLALLWKNRG 5eic B 1.50 BS01 5J5 B 1 P1110 F1111 V1115 L1120 I1122 P1123 A1164 Y1167 N1168 R1173 V1174 P32 F33 V37 L42 I44 P45 A86 Y89 N90 R95 V96 2.3.1.48 Q92793 SMRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL 5ek6 A 2.66 BS01 NAP A 1 I151 T152 P153 W154 N155 I160 K178 A180 S181 P210 G211 G215 F229 T230 G231 E232 T235 I239 E253 L254 G255 C287 E382 F384 F449 I143 T144 P145 W146 N147 I152 K170 A172 S173 P202 G203 G207 F221 T222 G223 E224 T227 I231 E245 L246 G247 C279 E374 F376 F441 G7VCG0 VANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5ek6 A 2.66 BS02 5OZ A 1 I160 K163 T230 E253 E443 F449 E460 I152 K155 T222 E245 E435 F441 E452 G7VCG0 VANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5ek6 B 2.66 BS01 NAP B 1 I151 T152 P153 W154 N155 I160 K178 A180 S181 P210 G211 P212 G215 E216 F229 T230 G231 E232 T235 E253 L254 G255 C287 E382 F384 F449 I145 T146 P147 W148 N149 I154 K172 A174 S175 P204 G205 P206 G209 E210 F223 T224 G225 E226 T229 E247 L248 G249 C281 E376 F378 F443 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5ek6 C 2.66 BS01 NAP C 1 I151 T152 P153 W154 N155 I160 K178 P179 A180 S181 P210 G211 P212 G215 E216 F229 T230 G231 E232 T235 E238 I239 E253 L254 G255 C287 E382 F384 F449 I145 T146 P147 W148 N149 I154 K172 P173 A174 S175 P204 G205 P206 G209 E210 F223 T224 G225 E226 T229 E232 I233 E247 L248 G249 C281 E376 F378 F443 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSALK 5ek6 D 2.66 BS02 5OZ D 1 I160 K163 T230 E253 E443 F449 I154 K157 T224 E247 E437 F443 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSALK 5ek9 A 2.08 BS01 5P4 A 1 W370 P371 F372 L381 L383 C425 N429 H433 D434 V435 M438 W23 P24 F25 L34 L36 C78 N82 H86 D87 V88 M91 P25440 EQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 5ek9 B 2.08 BS01 5P4 B 1 W370 P371 F372 V376 L381 L383 C425 N429 V435 W23 P24 F25 V29 L34 L36 C78 N82 V88 P25440 EQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP 5ekc A 1.90 BS01 NAP A 1 I151 T152 P153 W154 K178 A180 S181 D182 G211 G215 F229 T230 G231 E232 T235 I239 N332 R334 Q335 I145 T146 P147 W148 K172 A174 S175 D176 G205 G209 F223 T224 G225 E226 T229 I233 N326 R328 Q329 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5ekc B 1.90 BS01 NAP B 1 I151 T152 P153 W154 K178 A180 S181 P210 G211 G215 F229 G231 E232 T235 I239 N332 Q335 I146 T147 P148 W149 K173 A175 S176 P205 G206 G210 F224 G226 E227 T230 I234 N327 Q330 G7VCG0 IMKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5ekc C 1.90 BS01 NAP C 1 I151 T152 P153 W154 K178 A180 S181 P210 G211 G215 F229 T230 G231 E232 T235 E238 I239 N332 R334 Q335 I143 T144 P145 W146 K170 A172 S173 P202 G203 G207 F221 T222 G223 E224 T227 E230 I231 N324 R326 Q327 G7VCG0 VANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSALK 5ekc G 1.90 BS01 NAP G 1 I151 T152 P153 W154 K178 A180 S181 G211 G215 F229 T230 G231 E232 T235 I239 N332 Q335 I145 T146 P147 W148 K172 A174 S175 G205 G209 F223 T224 G225 E226 T229 I233 N326 Q329 G7VCG0 MKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSAFEALKAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVVFTERLIQNAAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTLRTRRFPIPSAL 5ekd A 1.82 BS01 5BX A 1 F38 S39 G40 Q42 V74 H77 Y160 Q164 D167 I168 V176 V178 Q182 F5 S6 G7 Q9 V41 H44 Y127 Q131 D134 I135 V143 V145 Q149 6.1.1.2 Q9UGM6 KKRVFSGIQPTGILHLGNYLGAIESWVRLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEHTQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL 5ekd A 1.82 BS02 ATP A 1 G40 I41 Q42 H48 G50 N51 G54 V178 G179 D181 Q182 M214 K215 K216 V217 K218 K226 M227 S228 K229 S230 G7 I8 Q9 H15 G17 N18 G21 V145 G146 D148 Q149 M181 K182 K183 V184 K185 K193 M194 S195 K196 S197 6.1.1.2 Q9UGM6 KKRVFSGIQPTGILHLGNYLGAIESWVRLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEHTQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTARYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL 5elg A 1.81 BS01 GSH A 1 C20 F22 L44 K47 K59 V60 P61 D72 S73 C19 F21 L43 K46 K58 V59 P60 D71 S72 2.5.1.18 Q9FWR4 ALEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDDKWVTDSDVIVGILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWAPKVNP 5eln A 1.90 BS01 LYS A 1 G249 A250 E273 E311 Y313 N467 Y469 E471 G516 W517 G205 A206 E229 E267 Y269 N423 Y425 E427 G472 W473 6.1.1.6 Q5CR27 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 5eln B 1.90 BS01 LYS B 1 G249 A250 A271 E273 E311 Y313 N467 Y469 E471 G516 W517 G518 G205 A206 A227 E229 E267 Y269 N423 Y425 E427 G472 W473 G474 6.1.1.6 Q5CR27 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 5elo A 1.90 BS01 LYS A 1 G249 E273 R295 E311 Y313 N467 Y469 E471 G516 W517 G518 G206 E230 R252 E268 Y270 N424 Y426 E428 G473 W474 G475 6.1.1.6 Q5CR27 GSHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 5elo A 1.90 BS02 KRS A 1 R295 E297 H303 N304 F307 A309 E464 L465 C466 N467 G518 G520 R523 R252 E254 H260 N261 F264 A266 E421 L422 C423 N424 G475 G477 R480 6.1.1.6 Q5CR27 GSHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMRN 5elo C 1.90 BS01 LYS C 1 G249 A250 A271 E273 R295 E311 Y313 N467 A468 Y469 E471 G516 G518 G201 A202 A223 E225 R247 E263 Y265 N419 A420 Y421 E423 G468 G470 6.1.1.6 Q5CR27 SHYTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDKDTTLSLSGRVTSIRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGELSLFSKSVVLLSPCYHMLPTAIDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFLADKNNIKEVILFPAMR 5enn A 2.70 BS01 5QS A 1 F612 S614 I634 K636 Y670 M682 Q683 F684 I685 S687 L750 I760 D761 F266 S268 I288 K290 Y324 M336 Q337 F338 I339 S341 L404 I414 D415 2.7.1.137 Q8NEB9 RDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLELEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFA 5enn B 2.70 BS01 5QS B 1 F612 I634 K636 Y670 M682 Q683 F684 I685 S687 L750 I760 D761 F272 I294 K296 Y330 M342 Q343 F344 I345 S347 L410 I420 D421 2.7.1.137 Q8NEB9 MGSGIRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALF 5erw A 2.90 BS01 III C 1 I52 F55 M59 S102 R103 G104 I53 F56 M60 S103 R104 G105 MQVQLVQSGAEVKKPGSSVKVSCEASGGTLSNYVITWVRQAPGQGLEWMGGFIPTFRTAMYAQGFQGRVTITADESTSIAYMELTNLRSEDTAVYYCARGPLSRGYYDYWGQGTLVTVSSAKTTAPSVYPLAPVCSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKI 5erw B 2.90 BS01 III C 1 G28 K30 S31 D50 W90 S92 S93 G28 K30 S31 D50 W90 S92 S93 SYVLTQPPSVSVAPGKTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSVVFGGWTKLTVLRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 5f9y A 2.80 BS01 PRO A 1 T300 E302 R331 W348 H352 F395 H421 W450 G451 T112 E114 R143 W160 H164 F207 H233 W262 G263 Q7YZ69 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETSPEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9y A 2.80 BS02 AMP A 1 R331 F340 I341 R342 T343 F346 Q416 T453 R455 R143 F152 I153 R154 T155 F158 Q228 T265 R267 Q7YZ69 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETSPEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9y A 2.80 BS03 ZN A 1 C621 C626 C671 F673 C433 C438 C471 F473 Q7YZ69 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETSPEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9y B 2.80 BS01 PRO B 1 T300 E302 R331 W348 E350 H352 F395 H421 S449 W450 T97 E99 R128 W145 E147 H149 F192 H218 S246 W247 Q7YZ69 SLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLEEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARGAMKSLCIPNDQIFTKCFFCDKLAKKFTLFGRSY 5f9y B 2.80 BS02 AMP B 1 R331 F340 I341 R342 T343 F346 Q416 A418 T419 G451 T453 R455 R128 F137 I138 R139 T140 F143 Q213 A215 T216 G248 T250 R252 Q7YZ69 SLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLEEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARGAMKSLCIPNDQIFTKCFFCDKLAKKFTLFGRSY 5f9y B 2.80 BS03 ZN B 1 C621 C626 C671 C674 C418 C423 C450 C453 Q7YZ69 SLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLEEVAWVTKSSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARGAMKSLCIPNDQIFTKCFFCDKLAKKFTLFGRSY 5f9z A 2.40 BS01 ANP A 1 R331 E333 F340 I341 R342 T343 F346 Q416 T419 T453 R455 R148 E150 F157 I158 R159 T160 F163 Q233 T236 T270 R272 Q7YZ69 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEGFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9z A 2.40 BS02 HFG A 1 L266 E274 G275 F276 E279 V280 P299 T300 E302 R331 W348 F395 T419 H421 W450 G451 L88 E91 G92 F93 E96 V97 P116 T117 E119 R148 W165 F212 T236 H238 W267 G268 Q7YZ69 AHHHHHHSKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEGFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5f9z B 2.40 BS02 HFG B 1 L266 F276 S277 E279 V280 P299 T300 E302 R331 W348 F395 T419 H421 W450 G451 L76 F86 S87 E89 V90 P109 T110 E112 R141 W158 F205 T229 H231 W260 G261 Q7YZ69 SLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEKDHVEGFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLSGAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5fjo A 2.08 BS01 NPQ A 1 F19 T21 Q26 R29 M50 S135 K161 K163 D189 N191 D239 K263 D291 M292 I293 Y323 F19 T21 Q26 R29 M50 S135 K161 K163 D189 N191 D239 K263 D291 M292 I293 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTQSVRELLLLRAVTPAGEGWGECVTMAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fjo A 2.08 BS02 MG A 1 K161 D189 N191 E214 D239 K161 D189 N191 E214 D239 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTQSVRELLLLRAVTPAGEGWGECVTMAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fjp A 2.58 BS01 NPQ A 1 F19 Q26 M50 S135 K161 K163 N191 K263 D291 M292 D316 Y323 F19 Q26 M50 S135 K161 K163 N191 K263 D291 M292 D316 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTQSVRELLLLRAVTPAGEGWGECVTMAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMGETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIGS 5fjp B 2.58 BS01 NPQ B 1 F19 Q26 R29 M50 S135 K161 K163 D189 N191 D239 K263 D291 M292 D316 Y323 F19 Q26 R29 M50 S135 K161 K163 D189 N191 D239 K263 D291 M292 D316 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTQSVRELLLLRAVTPAGEGWGECVTMAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMGETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIGS 5fjp C 2.58 BS01 NPQ C 1 F19 Q26 R29 M50 S135 K161 K163 N191 D239 K263 D291 M292 Y323 F19 Q26 R29 M50 S135 K161 K163 N191 D239 K263 D291 M292 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTQSVRELLLLRAVTPAGEGWGECVTMAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMGETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fjr A 2.44 BS01 NPQ A 1 F19 F23 A26 R29 I50 S135 K161 K163 D189 N191 K263 D291 M292 I293 Y323 F19 F23 A26 R29 I50 S135 K161 K163 D189 N191 K263 D291 M292 I293 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIGS 5fjr B 2.44 BS01 NPQ B 1 F19 F23 A26 R29 I50 S135 K161 K163 N191 D239 K263 D291 M292 I293 Y323 F19 F23 A26 R29 I50 S135 K161 K163 N191 D239 K263 D291 M292 I293 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fjr C 2.44 BS01 NPQ C 1 F19 T21 F23 R29 I50 S135 K161 K163 N191 D239 K263 D291 M292 I293 F19 T21 F23 R29 I50 S135 K161 K163 N191 D239 K263 D291 M292 I293 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fjr D 2.44 BS01 NPQ D 1 F19 A26 I50 S135 K161 K163 N191 D239 K263 D291 M292 I293 D316 F19 A26 I50 S135 K161 K163 N191 D239 K263 D291 M292 I293 D316 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fju A 2.52 BS02 5CR A 1 F19 F23 I50 Y55 S135 K161 K163 D189 N191 E214 D239 K263 D291 M292 I293 Y323 F19 F23 I50 Y55 S135 K161 K163 D189 N191 E214 D239 K263 D291 M292 I293 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIGS 5fju A 2.52 BS03 5CR A 2 F23 G24 T25 A26 V28 E30 I50 A51 G52 F23 G24 T25 A26 V28 E30 I50 A51 G52 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIGS 5fju B 2.52 BS03 5CR B 2 F23 G24 T25 A26 V28 I50 A51 G52 F23 G24 T25 A26 V28 I50 A51 G52 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fju C 2.52 BS03 5CR C 2 F19 I50 S135 K161 K163 D189 N191 E214 D239 K263 D291 M292 I293 Y323 F19 I50 S135 K161 K163 D189 N191 E214 D239 K263 D291 M292 I293 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fju D 2.52 BS01 MG D 1 D189 N191 E214 Q215 D239 E240 D189 N191 E214 Q215 D239 E240 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5fju D 2.52 BS03 5CR D 2 F19 I50 S135 K161 K163 D189 N191 K263 D291 M292 I293 Y323 F19 I50 S135 K161 K163 D189 N191 K263 D291 M292 I293 Y323 4.2.1.113 Q44244 MKLSGVELRRVQMPLVAPFRTSFGTASVRELLLLRAVTPAGEGWGECVTIAGPLYSSEYNDGAEHVLRHYLIPALLAAEDITAAKVTPLLAKFKGHRMAKGALEMAVLDAELRAHERSFAAELGSVRDSVPCGVSVGIMDTIPQLLDVVGGYLDEGYVRIKLKIEPGWDVEPVRAVRERFGDDVLLQVDANTAYTLGDAPQLARLDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDESIVSARAAADAIKLGAVQIVNIKPGRVGGYLEARRVHDVCAAHGIPVWCGDMIETGLGRAANVALASLPNFTLPGDTSASDRYYKTDITEPFVLSGGHLPVPTGPGLGVAPIPELLDEVTTAKVWIG 5flg A 2.04 BS01 PML A 1 R170 I171 A174 C192 S194 Y199 Y211 R213 R165 I166 A169 C187 S189 Y194 Y206 R208 6.2.1.14 P53559 EETFYSVRMRASMNGSDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEEDHD 5flg A 2.04 BS02 ANP A 1 H26 S28 G29 E31 K49 H53 V122 R123 G124 A125 V144 R145 V146 L177 S194 D195 D196 R227 H21 S23 G24 E26 K44 H48 V117 R118 G119 A120 V139 R140 V141 L172 S189 D190 D191 R222 6.2.1.14 P53559 EETFYSVRMRASMNGSDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEEDHD 5flg A 2.04 BS03 MG A 1 D195 D196 D190 D191 6.2.1.14 P53559 EETFYSVRMRASMNGSDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEEDHD 5flg B 2.04 BS01 PML B 1 R170 I171 S194 D196 Y199 T201 Y203 Y211 R213 R166 I167 S190 D192 Y195 T197 Y199 Y207 R209 6.2.1.14 P53559 ETFYSVRMRASMNGSHEDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEED 5fll A 2.34 BS01 WAQ A 1 E31 V122 R123 G124 A125 V144 R145 V146 R170 I171 A174 L177 C192 S194 D195 D196 Y199 T201 Y203 Y211 R213 R227 E25 V116 R117 G118 A119 V138 R139 V140 R164 I165 A168 L171 C186 S188 D189 D190 Y193 T195 Y197 Y205 R207 R221 6.2.1.14 P53559 EETFYSVRMRASMNGSGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEEDH 5fm0 B 2.44 BS01 WAQ B 1 E31 V122 R123 G124 A125 V144 R145 V146 R170 I171 L177 C192 W193 S194 D195 D196 Y199 T201 Y203 Y211 R213 R227 E22 V113 R114 G115 A116 V135 R136 V137 R161 I162 L168 C183 W184 S185 D186 D187 Y190 T192 Y194 Y202 R204 R218 6.2.1.14 P53559 ETFYSVRMRASMNGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEED 5g1x A 1.72 BS01 III B 1 K143 A172 G173 H176 R180 E183 W277 V279 H280 P282 R286 T288 L289 A290 G291 L293 L296 T333 Y334 Q335 Y338 K17 A46 G47 H50 R54 E57 W151 V153 H154 P156 R160 T162 L163 A164 G165 L167 L170 T207 Y208 Q209 Y212 2.7.11.1 O14965 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 5gjd A 2.79 BS01 6V3 A 1 V42 V50 A61 K63 E77 Q80 L81 I89 V90 M104 E105 Y106 A107 L144 I153 H154 L163 C174 D175 F176 V17 V25 A36 K38 E52 Q55 L56 I64 V65 M79 E80 Y81 A82 L119 I128 H129 L138 C149 D150 F151 2.7.11.25 Q15750 27803473 GPLHMIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPGRVEPYVDFAEFYRLWSVDH 5gjf A 2.89 BS01 6V4 A 1 V42 V50 A61 K63 E77 Q80 L81 V90 M104 E105 Y106 A107 L163 C174 D175 F176 V17 V25 A36 K38 E47 Q50 L51 V60 M74 E75 Y76 A77 L133 C144 D145 F146 2.7.11.25 Q15750 27803473 GPLHMIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIRKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPGRVEPYVDFAEFYRLWSVDHG 5gjg A 2.61 BS01 6V5 A 1 V42 G43 F47 A61 K63 V90 M104 E105 Y106 A107 E108 G110 S111 L163 C174 D175 F176 V17 G18 F22 A36 K38 V65 M79 E80 Y81 A82 E83 G85 S86 L138 C149 D150 F151 2.7.11.25 Q15750 27803473 GPLHMIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQHSLPGRVEPYVDFAEFYRLWSVDHG 5heb A 1.65 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 E331 S339 H372 E373 A376 L379 K380 F400 G26 L27 G28 F29 N30 I31 V32 E35 S43 H76 E77 A80 L83 K84 F104 P31016 27321669 GSPEFLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hed A 1.70 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 G329 G330 E331 S339 H372 E373 A376 L379 K380 R399 G25 L26 G27 F28 N29 I30 V31 G32 G33 E34 S42 H75 E76 A79 L82 K83 R102 P31016 27321669 SPEFLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hev A 3.19 BS01 MG A 1 D8 D9 D54 V56 M57 D8 D9 D54 V56 M57 S4FAU8 27670715 MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLISEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGL 5hev A 3.19 BS02 BEF A 1 D54 V56 T82 S83 F84 K104 D54 V56 T82 S83 F84 K104 S4FAU8 27670715 MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLISEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGL 5hev F 3.19 BS02 BEF F 1 D9 D54 L55 V56 T82 S83 F84 K104 D9 D54 L55 V56 T82 S83 F84 K104 S4FAU8 27670715 MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLISEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK 5hev B 3.19 BS01 MG B 1 D8 D9 D54 V56 D8 D9 D54 V56 S4FAU8 27670715 MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLISEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLV 5hev B 3.19 BS02 BEF B 1 D54 L55 V56 T82 S83 K104 D54 L55 V56 T82 S83 K104 S4FAU8 27670715 MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAMALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYLLKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLISEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLV 5hey A 1.50 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 G329 T330 S339 H372 A376 L379 K380 F400 G26 L27 G28 F29 N30 I31 V32 G33 T34 S43 H76 A80 L83 K84 F104 P31016 27321669 GSPEFLGEEDIPREPRRIVIHRGSTGLGFNIVGTEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hf1 A 1.75 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 G329 T330 E331 D332 S339 H372 E373 A376 L379 K380 F400 G24 L25 G26 F27 N28 I29 V30 G31 T32 E33 D34 S41 H74 E75 A78 L81 K82 F102 P31016 27321669 PEFLGEEDIPREPRRIVIHRGSTGLGFNIVGTEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hfb A 1.62 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 G329 E331 S339 A372 A376 L379 K380 G24 L25 G26 F27 N28 I29 V30 G31 E33 S41 A74 A78 L81 K82 P31016 27321669 PEFLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASAEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hfc A 1.85 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 E331 S339 A372 E373 A376 L379 K380 G24 L25 G26 F27 N28 I29 V30 E33 S41 A74 E75 A78 L81 K82 P31016 27321669 PEFLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASAEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hff A 1.75 BS01 III B 1 G322 L323 G324 F325 N326 I327 V328 G329 T330 E331 S339 A372 E373 A376 L379 K380 G25 L26 G27 F28 N29 I30 V31 G32 T33 E34 S42 A75 E76 A79 L82 K83 P31016 27321669 SPEFLGEEDIPREPRRIVIHRGSTGLGFNIVGTEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASAEQAAIALKNAGQTVTIIAQYKPEEYSRFEANSRVDSSGRIVTD 5hfj A 3.10 BS01 SAM A 1 D8 A9 D29 P30 P31 K165 K167 H168 P194 F195 M196 G197 S198 T200 E216 S217 E218 Y221 D8 A9 D29 P30 P31 K139 K141 H142 P164 F165 M166 G167 S168 T170 E186 S187 E188 Y191 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPYNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPVVSGLEKTKHSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRLNL 5hfj B 3.10 BS01 SAM B 1 A7 D8 A9 D29 P30 H168 T170 Q171 K172 P194 F195 M196 G197 S198 G199 E216 S217 Y221 A7 D8 A9 D29 P30 H133 T135 Q136 K137 P159 F160 M161 G162 S163 G164 E181 S182 Y186 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKKTKHPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRL 5hfj C 3.10 BS01 SAM C 1 D8 A9 D29 P31 H168 T170 Q171 K172 P194 F195 M196 G197 S198 G199 T200 E216 S217 E218 Y221 D8 A9 D29 P31 H141 T143 Q144 K145 P167 F168 M169 G170 S171 G172 T173 E189 S190 E191 Y194 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPDKNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPSGLEKTKHPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRLNL 5hfj D 3.10 BS01 SAM D 1 A7 D8 A9 D29 P31 F195 M196 G197 S198 E216 S217 E218 Y221 A7 D8 A9 D29 P31 F152 M153 G154 S155 E173 S174 E175 Y178 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRLNL 5hfj E 3.10 BS01 SAM E 1 D8 A9 D29 P169 K172 F195 G197 S198 G199 T200 E216 S217 D8 A9 D29 P132 K135 F158 G160 S161 G162 T163 E179 S180 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSHPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRLN 5hfj F 3.10 BS01 SAM F 1 D8 A9 D29 P31 T170 Q171 K172 P194 F195 M196 G197 S198 E216 S217 Y221 D8 A9 D29 P31 T133 Q134 K135 P157 F158 M159 G160 S161 E179 S180 Y184 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRLNL 5hfj G 3.10 BS01 SAM G 1 A7 D8 A9 D29 H168 T170 Q171 K172 F195 M196 G197 S198 G199 T200 E216 S217 E218 Y221 A7 D8 A9 D29 H139 T141 Q142 K143 F166 M167 G168 S169 G170 T171 E187 S188 E189 Y192 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPYDKNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPEKTKHPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRL 5hfj H 3.10 BS01 SAM H 1 A7 D8 A9 D29 P31 T170 Q171 P194 F195 M196 G197 S198 G199 T200 E216 S217 Y221 A7 D8 A9 D29 P31 T133 Q134 P157 F158 M159 G160 S161 G162 T163 E179 S180 Y184 O24891 27259995 MIQIYHADAFEIIKDFYQQNLKVDAIITDPPNFKLLEWIARYAPLVNPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPPTQKSLALMEKIISIHTNPNDIVLDPFMGSGTTGLACKNLERNFIGIESEKEYFQTAKKRLN 5hgr A 1.68 BS01 45D A 1 L37 T40 W41 F44 L107 W110 N111 G114 M117 I151 T152 R155 V158 Y203 L207 F242 C247 L250 L252 V275 T277 W279 F280 M286 M288 W290 I305 L35 T38 W39 F42 L105 W108 N109 G112 M115 I149 T150 R153 V156 Y201 L205 F240 C245 L248 L250 V273 T275 W277 F278 M284 M286 W288 I303 Q8YSD9 27208286 ITIDSARRIFPNTLQADAVPALTARFNQLSAEDQLAWTWFAFLEMGKTITVAAPGAASMQFAEGILKQIKEMTFEEQTQVMCDLANHTDTPICRTYATWSPNIKLGFWNQLGEWMEQGAVAPIPAGYQLSANANAVLETLKSLDQGQQITVLRSSVVDMGFDAAKLDGYTRVAEPLVAPKDISQRVQVTIEGINNSTVLNYMNNLNANDFDELIKLFVEDGALQPPFQRPIVGKDAILRFFREECQNLNLLPERGVAEPADDGYTQVKVTGKVQTPWFGAAVGMNMAWRFLLNPQGKIFFVAIDLLASPKELLNL 5hgr B 1.68 BS01 45D B 1 L37 T40 W41 F44 L107 W110 N111 G114 M117 I151 T152 L154 R155 V158 Y203 L207 P227 P228 F242 C247 L250 L252 V275 T277 W279 F280 M286 M288 W290 I305 L35 T38 W39 F42 L105 W108 N109 G112 M115 I149 T150 L152 R153 V156 Y195 L199 P219 P220 F234 C239 L242 L244 V267 T269 W271 F272 M278 M280 W282 I297 Q8YSD9 27208286 ITIDSARRIFPNTLQADAVPALTARFNQLSAEDQLAWTWFAFLEMGKTITVAAPGAASMQFAEGILKQIKEMTFEEQTQVMCDLANHTDTPICRTYATWSPNIKLGFWNQLGEWMEQGAVAPIPAGYQLSANANAVLETLKSLDQGQQITVLRSSVVDMGFDAAKVAEPLVAPKDISQRVQVTIEGINNSTVLNYMNNLNANDFDELIKLFVEDGALQPPFQRPIVGKDAILRFFREECQNLNLLPERGVAEPADDGYTQVKVTGKVQTPWFGAAVGMNMAWRFLLNPQGKIFFVAIDLLASPKELLNL 5hr5 A 1.82 BS01 F6P A 1 R257 H258 N264 I269 G270 E327 Y338 R352 K356 Y367 Q393 A394 R397 R230 H231 N237 I242 G243 E300 Y311 R325 K329 Y340 Q366 A367 R370 2.7.1.105,3.1.3.46 P26285 27802586 KCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTEESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPT 5hr5 A 1.82 BS02 FLC A 1 L75 G76 R79 F92 R103 A130 T131 Y198 L48 G49 R52 F65 R76 A103 T104 Y171 2.7.1.105,3.1.3.46 P26285 27802586 KCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTEESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPT 5hr5 A 1.82 BS03 ADP A 1 A49 R50 G51 K52 T53 Y54 V55 S157 N168 E171 V172 K173 V219 V222 V248 Y429 A22 R23 G24 K25 T26 Y27 V28 S130 N141 E144 V145 K146 V192 V195 V221 Y402 2.7.1.105,3.1.3.46 P26285 27802586 KCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTEESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPT 5htk A 2.01 BS02 ATP A 1 P47 A48 R49 G50 K51 T52 N73 V76 R79 E170 V171 S174 S175 P176 F190 A427 Y428 P17 A18 R19 G20 K21 T22 N43 V46 R49 E140 V141 S144 S145 P146 F160 A397 Y398 2.7.1.105,3.1.3.46 O60825 27802586 ASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPK 5ifu A 2.45 BS01 GBM A 1 F262 Y266 I276 L287 E404 R514 I516 G517 I520 M521 Y746 F12 Y16 I26 L37 E103 R213 I215 G216 I219 M220 Y438 6.1.1.15 Q8I5R7 27798837 ILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTSETIMYSVFPKWIRSYRDLPLKLNQWNTVTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 5ifu B 2.45 BS01 GBM B 1 Y266 I276 L287 E404 T513 R514 I516 G517 Y22 I32 L43 E117 T226 R227 I229 G230 6.1.1.15 Q8I5R7 27798837 HHHHSNILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY 5ilg A 2.40 BS01 MG A 1 G92 I93 M189 G96 I97 M193 1.1.1.1,1.1.1.105 Q7KNR7 HHVGTSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNKQSAADVSRCILNVLEKDKNGAVYVIEGKRVYPLEIKPQWTGKEQAL 5ilg A 2.40 BS02 NAD A 1 G12 G15 G16 I17 D37 L38 M62 D63 V64 V90 A91 G92 I93 V105 M135 S136 S137 Y150 K154 P182 G183 A184 T185 T187 M189 F190 G16 G19 G20 I21 D41 L42 M66 D67 V68 V94 A95 G96 I97 V109 M139 S140 S141 Y154 K158 P186 G187 A188 T189 T191 M193 F194 1.1.1.1,1.1.1.105 Q7KNR7 HHVGTSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNKQSAADVSRCILNVLEKDKNGAVYVIEGKRVYPLEIKPQWTGKEQAL 5ilg B 2.40 BS01 MG B 1 G16 T187 D188 G15 T186 D187 1.1.1.1,1.1.1.105 Q7KNR7 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNKQSAADVSRCILNVLEKDKNGAVYVIEGKRVYPLEIKPQWTGKEQ 5ilo A 2.71 BS01 NAD A 1 G12 G15 G16 I17 D37 L38 Q39 M62 D63 V64 V90 A91 G92 I93 V105 M135 S137 Y150 K154 G183 T185 T187 M189 G16 G19 G20 I21 D41 L42 Q43 M66 D67 V68 V94 A95 G96 I97 V109 M139 S141 Y154 K158 G187 T189 T191 M193 1.1.1.1,1.1.1.105 Q7KNR7 HHVGTSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSLNKQSAADVSRCILNVLEKDKNGAVYVIEGKRVYPLEIKPQWTGKEQAL 5jd2 B 1.90 BS01 BYY B 1 N23 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 D128 N8 S12 Y28 S30 V32 G33 N34 W64 A71 S73 T75 W77 W93 D113 P22629 27811937 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVK 5jd2 D 1.90 BS01 BYY D 1 N23 S27 Y43 V47 W79 S88 T90 W92 W108 D128 N8 S12 Y28 V32 W61 S70 T72 W74 W90 D110 P22629 27811937 GITGTWYNQLGSTFIVTAGADGALTGTYESAVESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVK 5jji A 2.60 BS01 NUC G 1 V284 L285 G287 G288 K326 V273 L274 G276 G277 K315 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jji A 2.60 BS03 BEF A 1 P180 K181 K184 R212 L320 P169 K170 K173 R201 L309 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jji B 2.60 BS01 NUC G 1 V284 L285 T286 G287 G288 K326 V276 L277 T278 G279 G280 K318 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMMK 5jji E 2.60 BS01 NUC G 1 V284 L285 T286 G287 G288 V268 L269 T270 G271 G272 3.6.4.- P0AG32 NLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jji E 2.60 BS05 BEF E 1 P180 K184 R212 P164 K168 R196 3.6.4.- P0AG32 NLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jji F 2.60 BS01 NUC G 1 T286 K326 T273 K310 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMMRKQDIIFAILKQHAKSGEIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jjk A 3.15 BS01 NUC G 1 V284 L285 G287 G288 V273 L274 G276 G277 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jjk A 3.15 BS05 ADP F 1 R366 K367 E369 R355 K356 E358 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jjk C 3.15 BS01 NUC G 1 G282 V284 L285 T286 G287 G288 K326 G276 V278 L279 T280 G281 G282 K320 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMGMRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMMK 5jjk D 3.15 BS01 NUC G 1 G282 V284 L285 T286 G287 G288 G271 V273 L274 T275 G276 G277 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMGKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jjk E 3.15 BS05 BEF E 1 K181 K184 R212 K121 K124 R152 3.6.4.- P0AG32 IFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jjl F 3.20 BS02 BEF F 1 P180 K181 K184 L320 P167 K168 K171 L306 3.6.4.- P0AG32 MNLTELKNTPVSELITLGENMMRKQDIIFAILKQHAKSGEIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM 5jpc A 2.50 BS01 FMC A 1 A9 M10 I52 V78 G80 Q152 F153 V154 V172 E173 M174 E175 R194 D198 A200 F208 A8 M9 I51 V77 G79 Q151 F152 V153 V171 E172 M173 E174 R193 D197 A199 F207 3.2.2.30,3.2.2.9 Q9ZMY2 QKIGILGAMREEITPILELFGVDFEEIPLGGNVFHKGVYHNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVAGSLVKDLKINDLLVATQLVQHDVDLSAFDHPLGFIPESAIFIETSGSLNALAKKIANEQHIALKEGVIASGDQFVHSKERKEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEKAGMSFDEFLEKSAHTSAKFLKSMVDEL 5k1z A 2.60 BS01 4CT A 1 A9 M10 I52 G53 V78 A79 G80 Q152 F153 V154 V172 E173 M174 E175 S197 D198 A200 A204 F208 A8 M9 I51 G52 V77 A78 G79 Q151 F152 V153 V171 E172 M173 E174 S196 D197 A199 A203 F207 3.2.2.30,3.2.2.9 Q9ZMY2 QKIGILGAMREEITPILELFGVDFEEIPLGGNVFHKGVYHNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVAGSLVKDLKINDLLVATQLVQHDVDLSAFDHPLGFIPESAIFIETSGSLNALAKKIANEQHIALKEGVIASGDQFVHSKERKEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEKAGMSFDEFLEKSAHTSAKFLKSMVDEL 5kcc B 2.39 BS01 III D 1 I358 L372 Q375 V376 L379 E380 D538 L539 E542 I50 L64 Q67 V68 L71 E72 D216 L217 E220 P03372 NSLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKNVVPLSDLLLEMLDAHRL 5kcd A 1.82 BS02 OB2 A 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 F404 V418 E419 G420 M421 I424 G521 H524 L525 L540 M39 L42 T43 A46 E49 L83 M84 L87 R90 F100 V114 E115 G116 M117 I120 G204 H207 L208 L223 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5kce A 1.85 BS01 III D 1 I358 K362 V376 E380 D538 L539 E542 M543 I47 K51 V65 E69 D212 L213 E216 M217 P03372 KNSLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 5kce B 1.85 BS01 III C 1 I358 L372 V376 E380 D538 L539 E542 M543 I54 L68 V72 E76 D229 L230 E233 M234 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKPLSDLLLEMLDAHR 5kce B 1.85 BS02 OB3 B 1 M343 L346 T347 A350 E353 L387 M388 R394 F404 V418 E419 G420 M421 I424 G521 H524 L525 M39 L42 T43 A46 E49 L83 M84 R90 F100 V114 E115 G116 M117 I120 G217 H220 L221 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKPLSDLLLEMLDAHR 5kcu A 2.03 BS02 OB8 A 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 F404 E419 G420 M421 I424 G521 H524 L525 M528 M34 L37 T38 A41 E44 L78 M79 L82 R85 F95 E110 G111 M112 I115 G202 H205 L206 M209 P03372 LALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNLSDLLLEMLDAHR 5kcu B 2.03 BS02 OB8 B 1 L346 T347 A350 E353 L387 M388 R394 F404 V418 M421 I424 G521 H524 L525 L540 L42 T43 A46 E49 L83 M84 R90 F100 V114 M117 I120 G210 H213 L214 L222 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSPLSDLLLEMLD 5kcw A 1.91 BS02 OB9 A 1 M343 L346 T347 A350 E353 L387 M388 R394 I424 G521 L525 M38 L41 T42 A45 E48 L82 M83 R89 I119 G206 L210 P03372 NSLALSLTADQMVSALLDAEPPILYSEYTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5knj A 2.88 BS01 6UX A 1 L217 A228 E250 T253 M254 L263 M283 E284 Y285 C286 G289 E293 L338 A348 G349 L25 A36 E52 T55 M56 L65 M85 E86 Y87 C88 G91 E95 L140 A150 G151 Q8NB16 IKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLST 5knj B 2.88 BS01 6UX B 1 L209 L217 A228 E250 M254 L263 M283 E284 Y285 C286 G289 E293 L320 L338 L347 A348 G349 L18 L26 A37 E59 M63 L72 M92 E93 Y94 C95 G98 E102 L129 L147 L156 A157 G158 Q8NB16 QIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTF 5ko1 A 2.16 BS01 6UY A 1 R210 E211 N212 S215 L217 A228 K230 E250 M283 E284 C286 S335 N336 L338 A348 G349 R19 E20 N21 S24 L26 A37 K39 E59 M92 E93 C95 S144 N145 L147 A157 G158 Q8NB16 QIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFS 5kod A 2.20 BS01 AMP A 1 S109 S110 I312 T314 M337 A339 S340 S341 Y360 D427 F443 R446 S92 S93 I295 T297 M320 A322 S323 S324 Y343 D392 F408 R411 6.3.2.- O81829 DQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHRQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDGNTPIPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWVPGHKQ 5kod A 2.20 BS02 IAC A 1 K160 P173 V174 L175 F232 K143 P156 V157 L158 F215 6.3.2.- O81829 DQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHRQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDGNTPIPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWVPGHKQ 5kod C 2.20 BS02 IAC C 1 K160 P173 V174 L175 F232 A339 K145 P158 V159 L160 F213 A320 6.3.2.- O81829 TLDQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHRNALTEKEQQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLDPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPK 5kod D 2.20 BS01 AMP D 1 S109 S110 I312 T314 G315 M337 Y338 A339 S340 S341 Y360 D427 F443 R446 S94 S95 I297 T299 G300 M322 Y323 A324 S325 S326 Y345 D392 F408 R411 6.3.2.- O81829 TLDQKNKQKLQLIEELTSNADQVQRQVLEEILTRNADVEYLRRHDLNGRTDRETFKNIMPVITYEDIEPEINRIANGDKSPILSSKPISEFLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKTPGGLPARPVLTSYYKSSHFKERPYDPYTNYTSPNETILCSDSYQSMYSQMLCGLCQHQEVLRVGAVFASGFIRAIKFLEKHWIELVRDIRTGTLSSLITDPSVREAVAKILKPSPKLADFVEFECKKSSWQGIITRLWPNTKYVDVIVTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTLIPSMAYFEFLPVHQELVDLVDVKLGQEYELVVTTYAGLCRYRVGDLLRVTGFKNKAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNAVTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCPIPPSVFEDCCLAVEESFNTVYRQGRVSDKSIGPLEIKIVEPGTFDKLMDYAISLGASINQYKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWVPGH 5kos A 2.41 BS01 6VS A 1 T18 Q19 Y20 V36 D38 G40 Y83 S84 T85 P118 F124 V127 Y162 L224 D226 T227 G228 A229 S230 T309 T15 Q16 Y17 V33 D35 G37 Y80 S81 T82 P115 F121 V124 Y159 L215 D217 T218 G219 A220 S221 T300 3.4.23.15 P00797 27774132 GNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 5kos B 2.41 BS01 6VS B 1 T18 Q19 Y20 V36 D38 G40 Y83 S84 T85 P118 L121 A122 F124 V127 Y162 L224 D226 T227 G228 A229 I305 T309 T15 Q16 Y17 V33 D35 G37 Y80 S81 T82 P115 L118 A119 F121 V124 Y159 L216 D218 T219 G220 A221 I297 T301 3.4.23.15 P00797 27774132 GNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 5kvh A 2.27 BS01 FAD A 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 L175 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 L311 L406 G437 D438 E453 H454 H455 A458 F482 W483 G13 G14 G15 T16 A17 V37 E39 D40 R47 P48 L50 S51 K52 K106 K107 V108 A134 T135 G136 F159 R160 L186 L281 G312 D313 E328 H329 H330 A333 F357 W358 1.1.1.- O95831 27818101 DKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQANGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHE 5kvi A 2.00 BS01 FAD A 1 G138 G139 G140 T141 A142 V162 E164 D165 R172 P173 L175 S176 K177 K231 K232 V233 A259 T260 G261 F284 R285 K286 L311 G437 D438 E453 H454 H455 A458 F482 W483 G10 G11 G12 T13 A14 V34 E36 D37 R44 P45 L47 S48 K49 K103 K104 V105 A131 T132 G133 F156 R157 K158 L183 G309 D310 E325 H326 H327 A330 F354 W355 1.1.1.- O95831 27818101 PSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLAIDSDFGGFAVNAELQAASNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHEDLEVLFQ 5l2j A 1.65 BS01 NAG A 1 N57 F58 R168 N54 F55 R165 P29016 27807341 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGLN 5l2j A 1.65 BS03 70E A 1 F10 H38 L66 V72 Y73 G76 F77 E80 A100 V126 C131 I148 Q152 I154 M155 T157 V158 L161 C166 Y169 F7 H35 L63 V69 Y70 G73 F74 E77 A97 V123 C128 I145 Q149 I151 M152 T154 V155 L158 C163 Y166 P29016 27807341 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRGSGLN 5l2k A 3.20 BS01 NAG A 1 N57 F58 R168 L171 N54 F55 R165 L168 P29016 27807341 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRALLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRG 5l2k A 3.20 BS02 NAG A 2 N20 T22 W23 N17 T19 W20 P29016 27807341 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRALLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRG 5l2k A 3.20 BS03 70E E 1 F10 V12 H38 L66 F70 V72 Y73 G76 F77 A100 L124 V126 C131 I148 G153 M155 L161 L162 Y169 F7 V9 H35 L63 F67 V69 Y70 G73 F74 A97 L121 V123 C128 I145 G150 M152 L158 L159 Y166 P29016 27807341 FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRALLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRG 5l2k D 3.20 BS01 70E E 1 N31 R107 G111 G112 N30 R91 G94 G95 27807341 GQNIDQPTEMTATEGAIVQINCTYQTSGFNGLFWYQQHAGEAPTFLSYNVLDGLEEKGRFSSFLSRSKGYSYLLLKELQMKDSASYLCAVRNTGGFKTIFGAGTRLFVKANIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACAN 5l2k E 3.20 BS01 70E E 1 Y31 R109 L110 A111 G112 D113 Y30 R95 L96 A97 G98 D99 27807341 AGVTQTPKFRVLKTGQSMTLLCAQDMNHEYMYWYRQDPGMGLRLIHYSVGEGTTAKGEVPDGYNVSRLKKQNFLLGLESAAPSQTSVYFCASSPRLAGDEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 5ljv A 3.65 BS02 ADP A 1 G19 T20 S21 H22 G163 A164 G189 N190 K218 E219 S222 G289 G290 R292 G10 T11 S12 H13 G154 A155 G180 N181 K209 E210 S213 G280 G281 R283 Q2W8Q6 27821762 NRLFLGVDLGTSHTAVMSSRGKKFLLKSVVGYPKDVIGLKLLGRPYVVGDEAFEMRSYLDIRYPLQDGVLSEISDRDIEVARHLLTHVVKSAEPGPNDEICAVIGVPARASAANKALLLKMAQEVVHTALVVSEPFMVGYGLDKLINTIIVDIGAGTTDICALKGTVPGPEDQVTLTKAGNYVDERLQNAILERHPELQMNVNVACAVKEQFSFVGTPTEVASFEFRAAGKPVRADVTEPVKIACEALMPDIIESIETLLRSFQPEYQATVLQNIVFAGGGSRIRGLAAYVKEKLRPFGDANVTCVKDPTFDGCRGALRLAEELP 5ljw A 1.80 BS01 ANP A 1 T20 S21 D76 G163 A164 G165 T166 G189 C215 K218 E219 S222 G288 G289 R292 I293 T17 S18 D73 G160 A161 G162 T163 G186 C212 K215 E216 S219 G285 G286 R289 I290 Q2W8Q6 27821762 GEGQAKNRLFLGVDLGTSHTAVMSSRGKKFLLKSVVGYPKDVIGLKLLGRPYVVGDEAFEMRSYLDIRYPLQDGVLSEISDRDIEVARHLLTHVVKSAEPGPNDEICAVIGVPARASAANKALLLKMAQEVVHTALVVSEPFMVGYGLDKLINTIIVDIGAGTTDICALKGTVPGPEDQVTLTKAGNYVDERLQNAILERHPELQMNVNVACAVKEQFSFVGTPTEVASFEFRAAGKPVRADVTEPVKIACEALMPDIIESIETLLRSFQPEYQDTVLQNIVFAGGGSRIRGLAAYVKEKLRPFGDANVTCVKDPTFDGCRGALRLAEELP 5ljw B 1.80 BS01 ANP B 1 G163 A164 G165 T166 G189 C215 K218 E219 S222 G288 G289 R292 I293 G156 A157 G158 T159 G182 C208 K211 E212 S215 G281 G282 R285 I286 Q2W8Q6 27821762 AKNRLFLGVDLGTSHTAVMSSRGKKFLLKSVVGYPKDVIGLKLLGRPYVVGDEAFEMRSYLDIRYPLQDGVLSEISDRDIEVARHLLTHVVKSAEPGPNDEICAVIGVPARASAANKALLLKMAQEVVHTALVVSEPFMVGYGLDKLINTIIVDIGAGTTDICALKGTVPGPEDQVTLTKAGNYVDERLQNAILERHPELQMNVNVACAVKEQFSFVGTPTEVASFEFRAAGKPVRADVTEPVKIACEALMPDIIESIETLLRSFQPEYQDTVLQNIVFAGGGSRIRGLAAYVKEKLRPFGDANVTCVKDPTFDGCRGALRLAEE 5lqx A 7.90 BS01 ATP A 1 R173 Q174 T178 A179 R364 P365 R167 Q168 T172 A173 R358 P359 27791192 PTEVSSILESKIRGVSDEANLDETGRVLSVGDGIARVFGLNNCQAEELVEFASGVKGMALNLEPGQVGIVLFGSDREVKEGEIVKRTGKIVDVPIGPGMLGRVVDALGNPIDGKGPIEATGYAIAQLKAPGILPRRSVFEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNDGNDESKKLYCVYVAVGQKRSTVAQLVQTLEQNDAMKYSIVVAATASEAAPLQYLAPFTACAIAEWFRDNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDANGGGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLSRGERLTQLLKQKQYSPQASEEQVPVIYAGVNGFLDNIPIERIPEFEEQFIAYLKANEGDILEAIRTKGELSSELLDKLKSATETFVAT 5lqx B 7.90 BS01 ADP B 1 D172 R173 Q174 T175 G176 K177 T178 A179 R364 Q432 K433 Q434 D168 R169 Q170 T171 G172 K173 T174 A175 R360 Q423 K424 Q425 27791192 KAAPTEVSSILESKIRVSDEANLDETGRVLSVGDGIARVFGLNNCQAEELVEFASGVKGMALNLEPGQVGIVLFGSDREVKEGEIVKRTGKIVDVPIGPGMLGRVVDALGNPIDGKGPIEATGYAIAQLKAPGILPRRSVFEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNDGNDESKKLYCVYVAVGQKRSTVAQLVQTLEQNDAMKYSIVVAATASEAAPLQYLAPFTACAIAEWFRDNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDANGGGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFALDASTKQTLSRGERLTQLLKQKQYSPQASEEQVPVIYAGVNGFLDNIPIERIPEFEEQFIAYLKANEGDILEAIRTKGELSSELLDKLKSATETFVAT 5lqx D 7.90 BS01 ADP D 1 G159 A160 G161 V162 G163 K164 T165 V166 Y346 A422 G154 A155 G156 V157 G158 K159 T160 V161 Y341 A417 27791192 AGPASGKIRAVIGAVVDVQFEQGELPAILNALTIDQGNNQKLVLEVAQHLGENAVRAIAMDGTEGLVRGQTVVDTGAPISVPVGRGTLGRIINVVGEPIDERGPIECKQRNPIHADPPSFVEQSTEAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFTGVGERTREGNDLYREMKETGVINLEGESKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERITTTRKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDVSVVGQEHYDVATGVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFAVAEVFTGIEGKLVRLKDTIASFKAVLEGKYDHLPENAFYMVGGIEDVVAKAEKIAA 5lqx E 7.90 BS01 ADP E 1 G159 A160 G161 G163 K164 T165 V166 Y346 A422 G152 A153 G154 G156 K157 T158 V159 Y339 A415 27791192 PASGKIRAVIGAVVDVQFEQGELPAILNALTIDQGNNQKLVLEVAQHLGENAVRAIAMDGTEGLVRGQTVVDTGAPISVPVGRGTLGRIINVVGEPIDERGPIECKQRNPIHADPPSFVEQSTEAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFTGVGERTREGNDLYREMKETGVINLEGESKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERITTTRKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDVSVVGQEHYDVATGVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFAVAEVFTGIEGKLVRLKDTIASFKAVLEGKYDHLPENAFYMVGGIEDVVAKAEKIAA 5lqx V 7.90 BS01 III X 1 L167 V171 D186 L119 V123 D138 27791192 DESILLVTFLGFIALISKTVAPLYGEMAKNRTDHVVGLLNQARADHVNAVKTRIDQVSNLKDVVSTTKALFEMSKETAALEAEAFELKQKVAVASEAKSVLDSWVRYEAQVRQHEQEQLASTVISKVQSELQNAKFQDKVLAQAVEEVERLFAK 5lqy V 7.80 BS01 III X 1 L167 V171 D186 L189 L119 V123 D138 L141 27791192 DESILLVTFLGFIALISKTVAPLYGEMAKNRTDHVVGLLNQARADHVNAVKTRIDQVSNLKDVVSTTKALFEMSKETAALEAEAFELKQKVAVASEAKSVLDSWVRYEAQVRQHEQEQLASTVISKVQSELQNAKFQDKVLAQAVEEVERLFAK 5lqz V 7.00 BS01 III X 1 L167 V171 D186 L189 V193 L119 V123 D138 L141 V145 27791192 DESILLVTFLGFIALISKTVAPLYGEMAKNRTDHVVGLLNQARADHVNAVKTRIDQVSNLKDVVSTTKALFEMSKETAALEAEAFELKQKVAVASEAKSVLDSWVRYEAQVRQHEQEQLASTVISKVQSELQNAKFQDKVLAQAVEEVERLFAK 5lsj A 3.25 BS01 III P 1 Q18 T19 L22 Y25 Q29 D30 F33 Q37 R61 L68 F79 S80 E83 Q17 T18 L21 Y24 Q28 D29 F32 Q36 R60 L67 F78 S79 E82 Q9H081 SVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQIRKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKEIEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVSLVQNSRKLQNIRDNVEKESK 5lsj D 3.25 BS01 III P 1 S203 S207 V208 S1 S5 V6 Q9H410 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVS 5lsj N 3.25 BS01 III P 1 I108 K109 E112 D113 F115 D116 I5 K6 E9 D10 F12 D13 Q96IY1 MDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGFSQV 5lsj C 3.25 BS01 III Q 1 Q18 T19 L22 Q29 F33 Q37 R61 K72 F79 E83 Q17 T18 L21 Q28 F32 Q36 R60 K71 F78 E82 Q9H081 SVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQIRKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKEIEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVSLVQNSRKLQNIRDNVEKESK 5lsj F 3.25 BS01 III Q 1 S203 L204 S207 M211 S1 L2 S5 M9 Q9H410 SLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVS 5lsj G 3.25 BS01 III Q 1 I108 K109 E112 D113 F115 I6 K7 E10 D11 F13 Q96IY1 FMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGFSQV 5lsk A 3.50 BS01 III P 1 Q18 L22 Y25 Q29 F33 Q37 E40 L68 K72 D76 F79 E83 Q17 L21 Y24 Q28 F32 Q36 E39 L67 K71 D75 F78 E82 Q9H081 SVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQIRKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKEIEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVSLVQNSRKLQNIRDNVEKESK 5lsk A 3.50 BS02 III P 2 F70 H74 K81 M82 L85 F69 H73 K80 M81 L84 Q9H081 SVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQIRKCTEKFLCFMKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKEIEQLQEKYKTELCTKQALLAELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVSLVQNSRKLQNIRDNVEKESK 5lsk B 3.50 BS01 III P 3 T31 L37 T40 M41 T44 K48 R57 T1 L7 T10 M11 T14 K18 R27 Q6P1K2 TISRVKLLDTMVDTFLQKLVAAGSYQRFTDCYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKEPAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQVQAQQQAWQALHREQRELVAVLRE 5lsk D 3.50 BS01 III P 1 L204 S207 M211 L77 S80 M84 Q9H410 GITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDFSLESFRAKASSLSEELKHFADGLETDGTLQKCFESLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVS 5lsk N 3.50 BS01 III P 1 D105 I108 K109 E112 D113 F115 D116 D74 I77 K78 E81 D82 F84 D85 Q96IY1 PREDFRVRCTSKRAVTEMLQLCGRFVQKLGDALPEEIREPALRDAQWTFESAVQENISINGQAWQEASDNCFMDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKAKQEILKQYHPVVHPLDLKYDPDPAPHMENLKCRGETVAKEISEAMKSLPALIEQGEGFSQV 5lw7 B 17.00 BS01 SF4 B 1 R6 I50 C55 T56 G57 C58 G59 C61 I72 R6 I50 C55 T56 G57 C58 G59 C61 I72 Q9UZA4 27824037 MVRKMRIAVIDYDKCNPDKCGHFLCERVCPVNRMGGEAIIIDEENYKPIIQEASCTGCGICVHKCPFNAISIVNLPEQLDEDCVHRYGVNAFVLYRLPIVKDGMVVGIVGPNGTGKTTAVKILAGQLIPNLCEDNDSWDNVIRAFRGNELQNYFERLKNGEIRPVVKPQYVDLLPKAVKGKVRELLKKVDEVGKFEEVVKELELENVLDRELHQLSGGELQRVAIAAALLRKAHFYFFDEPSSYLDIRQRLKVARVIRRLANEGKAVLVVEHDLAVLDYLSDVIHVVYGEPGVYGIFSKPKGTRNGINEFLQGYLKDENVRFRPYEIRFTKLSERVDVERETLVEYPRLVKDYGSFKLEVEPGEIRKGEVIGIVGPNGIGKTTFVKMLAGVEEPTEGKVEWDLTVAYKPQYIKAEYEGTVYELLSKIDSSKLNSNFYKTELLKPLGIIDLYDRNVEDLSGGELQRVAIAATLLRDADIYLLDEPSAYLDVEQRLAVSRAIRHLMEKNEKTALVVEHDVLMIDYVSDRLIVFEGEPGRHGRALPPMGMREGMNRFLASVGITFRRDPDSGRPRANKEGSVKDREQKARGEYYYA 5lw7 B 17.00 BS02 SF4 B 2 C15 N16 P17 C20 F23 L24 C25 P48 C65 A69 I70 C15 N16 P17 C20 F23 L24 C25 P48 C65 A69 I70 Q9UZA4 27824037 MVRKMRIAVIDYDKCNPDKCGHFLCERVCPVNRMGGEAIIIDEENYKPIIQEASCTGCGICVHKCPFNAISIVNLPEQLDEDCVHRYGVNAFVLYRLPIVKDGMVVGIVGPNGTGKTTAVKILAGQLIPNLCEDNDSWDNVIRAFRGNELQNYFERLKNGEIRPVVKPQYVDLLPKAVKGKVRELLKKVDEVGKFEEVVKELELENVLDRELHQLSGGELQRVAIAAALLRKAHFYFFDEPSSYLDIRQRLKVARVIRRLANEGKAVLVVEHDLAVLDYLSDVIHVVYGEPGVYGIFSKPKGTRNGINEFLQGYLKDENVRFRPYEIRFTKLSERVDVERETLVEYPRLVKDYGSFKLEVEPGEIRKGEVIGIVGPNGIGKTTFVKMLAGVEEPTEGKVEWDLTVAYKPQYIKAEYEGTVYELLSKIDSSKLNSNFYKTELLKPLGIIDLYDRNVEDLSGGELQRVAIAATLLRDADIYLLDEPSAYLDVEQRLAVSRAIRHLMEKNEKTALVVEHDVLMIDYVSDRLIVFEGEPGRHGRALPPMGMREGMNRFLASVGITFRRDPDSGRPRANKEGSVKDREQKARGEYYYA 5lwp A 2.40 BS01 79U A 1 W317 L324 T325 I328 Q329 L353 K354 M358 C476 V480 L483 Q484 A496 A497 F498 L501 Y502 L505 F506 W55 L62 T63 I66 Q67 L91 K92 M96 C214 V218 L221 Q222 A234 A235 F236 L239 Y240 L243 F244 P51449 27815118 HMASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELF 5lx2 A 2.58 BS01 III B 1 S47 V48 K51 R58 F122 K125 R132 Y133 L177 N178 V181 E185 L225 N229 L232 W233 S44 V45 K48 R55 F119 K122 R129 Y130 L174 N175 V178 E182 L222 N226 L229 W230 C5DN49 SREDSVYLAKLAEQAERYEEMVDSMKAVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEEAKDKSEHQVKLIRDYRSKIETELTKICDDILSVLDTHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGEVRDKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMS 5m05 A 2.68 BS01 52E A 1 M89 A90 V100 S117 G118 L119 F120 F493 M497 E501 F517 G709 V710 E712 G713 I714 C717 P722 R724 M57 A58 V68 S85 G86 L87 F88 F446 M450 E454 F470 G629 V630 E632 G633 I634 C637 P642 R644 P10587 27815532 KLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSPYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGAAVVEKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKFQKSDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEE 5m05 A 2.68 BS02 MG A 1 T184 S246 T152 S199 P10587 27815532 KLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSPYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGAAVVEKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKFQKSDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEE 5m05 A 2.68 BS03 ADP A 1 N125 P126 Y127 K128 Y133 G180 A181 G182 K183 T184 E185 N242 N93 P94 Y95 K96 Y101 G148 A149 G150 K151 T152 E153 N195 P10587 27815532 KLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSPYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGAAVVEKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKFQKSDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEE 5m5s A 1.88 BS01 III E 1 R64 P65 I66 S67 L82 K83 A84 T87 Q89 F91 K96 K98 R61 P62 I63 S64 L79 K80 A81 T84 Q86 F88 K93 K95 P49951 27813245 ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL 5m5s A 1.88 BS02 III G 1 L183 S185 V190 Q192 F216 H229 I231 E232 V233 K245 K246 A247 L180 S182 V187 Q189 F213 H226 I228 E229 V230 K242 K243 A244 P49951 27813245 ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL 5m5t A 1.70 BS02 III G 1 L5 I7 F9 Q10 E11 H12 N296 R297 I298 S299 G300 L2 I4 F6 Q7 E8 H9 N293 R294 I295 S296 G297 P49951 27813245 ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL 5m5t A 1.70 BS03 III I 1 L183 S185 R188 V190 Q192 F216 I231 E232 V233 K245 L180 S182 R185 V187 Q189 F213 I228 E229 V230 K242 P49951 27813245 ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL 5m5t B 1.70 BS02 III H 1 L5 I7 R8 F9 Q10 E11 H12 Y281 N296 R297 I298 S299 G300 Q323 L2 I4 R5 F6 Q7 E8 H9 Y278 N293 R294 I295 S296 G297 Q320 P49951 27813245 ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL 5m5t B 1.70 BS03 III J 1 L183 S185 R188 V190 Q192 F216 I231 V233 K245 L180 S182 R185 V187 Q189 F213 I228 V230 K242 P49951 27813245 ILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEEL 5m9n A 1.95 BS01 III C 1 F551 E553 D554 Q556 Y558 Y575 Y578 N580 F78 E80 D81 Q83 Y85 Y102 Y105 N107 Q9BXT4 NIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGFAVGE 5m9n B 1.95 BS01 2MR B 1 H501 F551 Y558 Y575 Y578 N580 H29 F79 Y86 Y103 Y106 N108 Q9BXT4 NNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSEHVSVSKVLLDAGFA 5t41 A 3.15 BS01 EDO A 1 Q18 G20 T22 Q14 G16 T18 3.1.3.3 A0QJI1 PKVSVLITVTGVDQPGVTATLFEVLSRHGVELLNVEQVVIRHRLTLGVLVCCPADVADGPALRHDVEAAIRKVGLDVSIERSDDVPIIREPSTHTIFVLGRPITAAAFGAVAREVAALGVNIDLIRGVSDYPVIGLELRVSVPPGADGALRTALNRVSSEEHVDVAVEDYTLERRAKRLIVFDVDSTLVQGEVIEMLAAKAGAEGQVAAITDAAMRGELDFAQSLQQRVATLAGLPATVIDEVAGQLELMPGARTTLRTLRRLGYACGVVAGGFARIIEPLAEELMLDYVAANELEIVDGTLTGRVVGPIIDRAGKATALREFAQRAGVPMAQTVAVGDGANDIDMLAAAGLGIAFNAKPALREVADASLSHPYLDTVLFLLGVTRGEIEAADAID 5t45 A 2.80 BS03 BEF A 1 S179 K183 N242 S245 S246 S147 K151 N195 S198 S199 27815532 KLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSPYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKFQKSKDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEE 5t45 A 2.80 BS04 ADP A 1 I113 N125 P126 Y127 K128 Y133 S179 G180 A181 G182 K183 T184 E185 N242 I81 N93 P94 Y95 K96 Y101 S147 G148 A149 G150 K151 T152 E153 N195 27815532 KLVWVPSEKHGFEAASIKEEKGDEVTVELQENGKKVTLSKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKQLPIYSEKIIDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSPYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAKDERTFHIFYYLIAGASEQMRNDLLLEGFNNYTFLSNGHVPIPAQQDDEMFQETLEAMTIMGFTEEEQTSILRVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAIEALAKAKFERLFRWILTRVNKALDKTKRQGASFLGILDIAGFEIFEINSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPTNPPGVLALLDEECWFPKATDTSFVEKLIQEQGNHAKFQKSKDKTEFCILHYAGKVTYNASAWLTKNMDPLNDNVTSLLNQSSDKFVADLWKDRTVGQLYKEQLTKLMTTLRNTNPNFVRCIIPNHEKRAGKLDAHLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEE 5tj3 A 1.70 BS01 ZN A 1 D38 T79 D352 H353 D15 T56 D329 H330 3.1.3.1 Q9KJX5 27670607 NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVTAIGHTSIFTGSVPSIHGIAGNDWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLKDRASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFDMKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSAYSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG 5tj3 A 1.70 BS02 ZN A 2 T79 D305 H309 H486 T56 D282 H286 H461 3.1.3.1 Q9KJX5 27670607 NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVTAIGHTSIFTGSVPSIHGIAGNDWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLKDRASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFDMKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSAYSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG 5tj3 A 1.70 BS03 ZN A 3 D233 E238 P247 E317 D210 E215 P224 E294 3.1.3.1 Q9KJX5 27670607 NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVTAIGHTSIFTGSVPSIHGIAGNDWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLKDRASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFDMKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSAYSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG 5tj3 A 1.70 BS04 ZN A 4 D291 I293 D295 D268 I270 D272 3.1.3.1 Q9KJX5 27670607 NAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPTVTAIGHTSIFTGSVPSIHGIAGNDWYDKELGKSVYCTSDETVQPVGTTSNSVGQHSPRNLWSTTVTDQLGLATNFTSKVVGVSLKDRASILPAGHNPTGAFWFDDTTGKFITSTYYTKELPKWVNDFNNKNVPAQLVANGWNTLLPINQYTESSEDNVEWEGLLGSKKTPTFPYTDLAKDYEAKKGLIRTTPFGNTLTLQMADAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKVGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFDMKKEMNAKLKQKFGADNIIAAAMNYQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGYNWKRSGDIQIISKDGYLSAYSKKGTTHSVWNSYDSHIPLLFMGWGIKQGESNQPYHMTDIAPTVSSLLKIQFPSGAVGKPITEVIG 5tk7 A 1.90 BS01 MG A 1 H31 H66 D67 D132 H30 H65 D66 D131 O24769 SSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRY 5tk7 A 1.90 BS02 7D4 A 1 R16 W17 H75 I77 S78 K81 D132 I154 R15 W16 H74 I76 S77 K80 D131 I153 O24769 SSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRY 5tk8 A 1.64 BS01 7D5 A 1 R16 W17 H75 I77 S78 P79 K81 I154 R15 W16 H74 I76 S77 P78 K80 I153 O24769 SSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRY 5tk8 A 1.64 BS02 MG A 1 H31 D67 D132 H30 D66 D131 O24769 SSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRY 5tk9 A 1.84 BS02 7D7 A 1 R16 W17 H75 I77 S78 P79 R15 W16 H74 I76 S77 P78 O24769 SSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHIISPVKKNSILKDPFNAFREQIKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNYRY 5tka A 2.05 BS01 MG A 1 H31 H66 D67 D132 H30 H65 D66 D109 O24769 SSLLDIIYQLRQVPRWDGSFQFEKEDVSQHSFSVIAISHILCELKETLEGKKINKEKLLLYALYHDVTEVVSTHKNSLFDNLPITLSDTLSTILNNNDLEIQEIVEHADHVDAYCKSCIEVHRGNKDFISIQRSLGDKLDNLTKEYPYLKEFQNLFLKDFPLENKNY 5tky A 2.60 BS01 ATP A 1 G15 T16 T17 Y18 K74 G205 G206 G207 A208 E272 K275 R276 S279 G342 G343 S344 R346 I347 G12 T13 T14 Y15 K71 G202 G203 G204 A205 E269 K272 R273 S276 G339 G340 S341 R343 I344 G0SCU5 EVYDGAIGIDLGTTYSCVAVYEGTNVEIIANEQGNFTTPSFVSFTENCRLIGEAAKNQAAMNPANTIFDVKRLIGRRFDDPTVKKDMESWPFKVVDDNGNPKVEVQYLGQTHTFSPQEISAMVLTKMKEIAETKLGKKVEKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGSGKSDKERNVLIYDLGGGAFDVSLLNIQGGVFTVKATAGDTHLGGQDFDTNLLEYCKKEFTRKTKKDLSGDARALRRLRTACERAKRTLSSGAQTTIEIDSLFDGEDFNIQITRARFEDLNAKAFAGTLEPVAQVLKDAGIEKHQVDEIVLVGGSTRIPRIQKLLSEFFDGKKLEKSINPDEAVAYGAAVQAGILSGKATSADDLLLLDVVPLSLGVAMEGNIFAPVVPRGQTVPTIKKRTFTTVADNQQTVQFPVYQGERVNCEDNTLLGEFTLAPIPPMKAGEPVLEVVFEVDVNGILKVTATEKTSGRSANITIANSVGKLSTDEIEKMISDAEKFKSKCEAFSKRFEAKQQLESYISRVEEIISDKDKIEQALSEAMAQLEIEDSTADELKKKELALKRLVTKAMAS 5trt A 1.85 BS01 NAD A 1 G13 L15 I20 V40 C63 D64 V65 S91 I92 G93 L144 S145 Y146 K163 A189 G190 P191 I192 G13 L15 I20 V40 C63 D64 V65 S91 I92 G93 L144 S145 Y146 K163 A189 G190 P191 I192 1.3.1.9 Q3JQY0 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAVVGGMA 5trt B 1.85 BS01 NAD B 1 G13 L15 S19 I20 V40 C63 D64 V65 S91 I92 G93 I119 L144 S145 Y146 K163 A189 G190 P191 I192 G13 L15 S19 I20 V40 C63 D64 V65 S91 I92 G93 I119 L144 S145 Y146 K163 A189 G190 P191 I192 1.3.1.9 Q3JQY0 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAVVGGMA 5tsd A 1.90 BS01 NDP A 1 A74 R92 M102 G146 L147 G148 I149 L150 W168 S169 R170 T171 K173 L199 L200 P201 A232 G233 R234 D258 H282 A285 Y319 A71 R89 M99 G143 L144 G145 I146 L147 W165 S166 R167 T168 K170 L196 L197 P198 A229 G230 R231 D255 H279 A282 Y316 Q2KDT2 RPPVLVDIKFNPEGVDRVLKTAFADRGSINLADPANRERDFSETEYALLWKPDADLFRRAPNLKVIFSGGAGVDHIIGMAGLPDIPIVRFVDRSLTTRMSEWVVMQCLMHLRGQYGHDSHQRRREWAKLIAPEAAEVTVGVMGLGILGQDAVAKLKVMGFNVIGWSRTRKTIEGVETFDAGELDRFLAKTDILVGLLPLTPETTGFYDSELFKKLRRDGALGQPVFINAGRGKSQIETDIVSAVREGTLGGASLDVFEVEPLATDSPLWELENVFITPHDAAVSEENALFRHVEMQIARFERGEPLQFVIDRAAGY 5tsd A 1.90 BS02 OXD A 1 W53 G73 A74 G75 R234 H282 W50 G70 A71 G72 R231 H279 Q2KDT2 RPPVLVDIKFNPEGVDRVLKTAFADRGSINLADPANRERDFSETEYALLWKPDADLFRRAPNLKVIFSGGAGVDHIIGMAGLPDIPIVRFVDRSLTTRMSEWVVMQCLMHLRGQYGHDSHQRRREWAKLIAPEAAEVTVGVMGLGILGQDAVAKLKVMGFNVIGWSRTRKTIEGVETFDAGELDRFLAKTDILVGLLPLTPETTGFYDSELFKKLRRDGALGQPVFINAGRGKSQIETDIVSAVREGTLGGASLDVFEVEPLATDSPLWELENVFITPHDAAVSEENALFRHVEMQIARFERGEPLQFVIDRAAGY 5tu0 A 1.90 BS01 MAL A 1 D99 Y193 W270 D65 Y159 W236 Q929P4 SDEKTLTVSVDAGYKDYVNKIKGDFEKDNDVKVKVVEKDMFETLEALPLDGPAGTAPDVMMSAFDRIGSLGQQGHLAEVKLGNKDDYDEKDQKQVTIDDKIYGAPAIIETLVLYYNKDLLDKAPATFKDLETLSKDSRFAFTSEKGKNTGFLAKWTDFYFSYGLLAGYGGYVFGDEGTNPKDIGLNNKGSVEGITYATKWFQDVWPKGMQDNKSADDFIQDQFVKGKAAAILGGPWSAANYKEAKINYGVAKIPTLNNGKEYSPFAGGKGWVVSNYSKNKDVAQKWLDYVTNQKNQETLYDMTNEVPANLKARDTAKSKNDELTNAVIEQYKNAQPMPNIPEMSEVWTGAENLKFDAASGSKTPQPSADDAVKVIEDNVTQKYTK 5tu0 A 1.90 BS02 TTN A 1 S311 K312 N313 K314 D315 S277 K278 N279 K280 D281 Q929P4 SDEKTLTVSVDAGYKDYVNKIKGDFEKDNDVKVKVVEKDMFETLEALPLDGPAGTAPDVMMSAFDRIGSLGQQGHLAEVKLGNKDDYDEKDQKQVTIDDKIYGAPAIIETLVLYYNKDLLDKAPATFKDLETLSKDSRFAFTSEKGKNTGFLAKWTDFYFSYGLLAGYGGYVFGDEGTNPKDIGLNNKGSVEGITYATKWFQDVWPKGMQDNKSADDFIQDQFVKGKAAAILGGPWSAANYKEAKINYGVAKIPTLNNGKEYSPFAGGKGWVVSNYSKNKDVAQKWLDYVTNQKNQETLYDMTNEVPANLKARDTAKSKNDELTNAVIEQYKNAQPMPNIPEMSEVWTGAENLKFDAASGSKTPQPSADDAVKVIEDNVTQKYTK 5tvg A 2.30 BS01 UDP A 1 V263 R265 K270 P300 K341 R344 L347 N367 L368 V369 E372 V268 R270 K275 P305 K346 R349 L352 N372 L373 V374 E377 2.4.1.15 A4JGS8 HHHHHMSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKQTGGVWFGWNGEIVGTPDAAPAVRRDGNVTYATLGLTRRDYDQYYRGFSNATLWPVFHYRSDLARFDRQEYAGYLRVNAMLARQLAALLRPDDLIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPDMLRVVPPHDELVKFMCAYDIAGFQTDADKRAFSDYIERRGIGTASDDGMLHAHGRVVKVAAYPIGVYPDAIAEAAVQYGGRKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQSFERMLAGAPDWQGRVSFVQIAPPTRSDVQTYQRIRETLEREAGRINGRFAQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELGGALLVNPYDHAQMADALARALAMPLAERQARHEENLAQLRNNDLSVWRDTFVADLRSVAAAASVT 5tvg A 2.30 BS02 MG A 1 F351 R352 M353 S354 Q377 F356 R357 M358 S359 Q382 2.4.1.15 A4JGS8 HHHHHMSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKQTGGVWFGWNGEIVGTPDAAPAVRRDGNVTYATLGLTRRDYDQYYRGFSNATLWPVFHYRSDLARFDRQEYAGYLRVNAMLARQLAALLRPDDLIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPDMLRVVPPHDELVKFMCAYDIAGFQTDADKRAFSDYIERRGIGTASDDGMLHAHGRVVKVAAYPIGVYPDAIAEAAVQYGGRKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQSFERMLAGAPDWQGRVSFVQIAPPTRSDVQTYQRIRETLEREAGRINGRFAQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELGGALLVNPYDHAQMADALARALAMPLAERQARHEENLAQLRNNDLSVWRDTFVADLRSVAAAASVT 5tvg B 2.30 BS01 UDP B 1 V263 R265 K270 Y342 R344 L347 L368 V369 E372 V253 R255 K260 Y332 R334 L337 L358 V359 E362 2.4.1.15 A4JGS8 HMSRLIVVSNRVAGGLAVGVMDALKQTGGVWFGWNGEIVGTPDAAPAVRRDGNVTYATLGLTRRDYDQYYRGFSNATLWPVFHYRSDLARFDRQEYAGYLRVNAMLARQLAALLRPDDLIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPDMLRVVPPHDELVKFMCAYDIAGFQTDADKRAFSDYIERRGIGTASGMLHAHGRVVKVAAYPIGVYPDAIAEAAVQYGGRKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQSFERMLAGAPDWQGRVSFVQIAPPTRSDVQTYQRIRETLEREAGRINGRFAQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELGGALLVNPYDHAQMADALARALAMPLAERQARHEENLAQLRNNDLSVWRDTFVADLRSVAAAASVTQ 5tvg C 2.30 BS01 UDP C 1 V263 R265 K270 Y342 R344 L347 N367 L368 V369 E372 V253 R255 K260 Y332 R334 L337 N357 L358 V359 E362 2.4.1.15 A4JGS8 MSRLIVVSNRVAPSAGGLAVGVMDALKQTGGVWFGWNGEIVGTPDAAPAVRRDGNVTYATLGLTRRDYDQYYRGFSNATLWPVFHYRSDLARFDRQEYAGYLRVNAMLARQLAALLRPDDLIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPDMLRVVPPHDELVKFMCAYDIAGFQTDADKRAFSDYIERRGIGTGMLHAHGRVVKVAAYPIGVYPDAIAEAAVQYGGRKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQSFERMLAGAPDWQGRVSFVQIAPPTRSDVQTYQRIRETLEREAGRINGRFAQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELGGALLVNPYDHAQMADALARALAMPLAERQARHEENLAQLRNNDLSVWRDTFVADLRSVAAAASVTQRAGR 5tvg D 2.30 BS01 UDP D 1 V263 R265 K270 K341 Y342 R344 L347 N367 L368 V369 E372 V263 R265 K270 K341 Y342 R344 L347 N367 L368 V369 E372 2.4.1.15 A4JGS8 HHHHMSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKQTGGVWFGWNGEIVGTPDAAPAVRRDGNVTYATLGLTRRDYDQYYRGFSNATLWPVFHYRSDLARFDRQEYAGYLRVNAMLARQLAALLRPDDLIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPDMLRVVPPHDELVKFMCAYDIAGFQTDADKRAFSDYIERRGIGTGMLHAHGRVVKVAAYPIGVYPDAIAEAAVQYGGRKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQSFERMLAGAPDWQGRVSFVQIAPPTRSDVQTYQRIRETLEREAGRINGRFAQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELGGALLVNPYDHAQMADALARALAMPLAERQARHEENLAQLRNNDLSVWRDTFVADLRSV 5tvg D 2.30 BS02 MG D 1 F351 R352 S354 Q377 G383 F351 R352 S354 Q377 G383 2.4.1.15 A4JGS8 HHHHMSRLIVVSNRVAAGEDTRPSAGGLAVGVMDALKQTGGVWFGWNGEIVGTPDAAPAVRRDGNVTYATLGLTRRDYDQYYRGFSNATLWPVFHYRSDLARFDRQEYAGYLRVNAMLARQLAALLRPDDLIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPDMLRVVPPHDELVKFMCAYDIAGFQTDADKRAFSDYIERRGIGTGMLHAHGRVVKVAAYPIGVYPDAIAEAAVQYGGRKPVKMLRDALGGRKLVMSVDRLDYSKGLVERFQSFERMLAGAPDWQGRVSFVQIAPPTRSDVQTYQRIRETLEREAGRINGRFAQLDWTPIQYLNRKYERNLLMAFFRMSQVGYVTPLRDGMNLVAKEYVASQDPADPGVLVLSEFAGAAAELGGALLVNPYDHAQMADALARALAMPLAERQARHEENLAQLRNNDLSVWRDTFVADLRSV