3jd5 h 7.00 BS01 III z 1 F324 D326 R339 E343 F41 D43 R56 E60 P82925 24799711 PFQNGFEEMIQWTKEGKLWEFPINNEAGFDDDGSEFHEHIFLDKYLEGFPKQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKQDILKESGINFS 3jd5 k 7.00 BS01 III z 1 Y226 T229 V230 H233 Y176 T179 V180 H183 Q2YDF6 24799711 RRKALPPRTEKMSVDQDWPSVYPVAAPFKPSAVPLPVRMGYPVKRGVPMAKEGNLELLKIPNFLHLTPVAIKKHCEALKDFCTEWPAALDSDEKCEKHFPIEIDTADYISSGPSIRNPKARVVTLRVKLSSLNLDDHAKKKLIKLVGDRYCKSTDVLTIKTDRCPLKRQNYDYAMYLLTVLYHESWKTEEWEKKKTEADMEEYVWKDSASEKNILETLFQIKAAEKNTELSKEELLSTKEVEDYKNSVVSLKNEGDNENTISQYKESVKRLLHLM 3jd5 o 7.00 BS01 III s 1 K111 T444 G445 D446 K56 T276 G277 D278 Q2KI62 24799711 EVVIPKKKTWDKVAVLQALASTVHRDTTAAPYAFQDDPYLIPTSSVESHSFLLAKKSGENAAKFIINSYPKYFQKDIAEPHIPCLMPEGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSLATYHHIIQLFYGGGGGGGGGGGGGGMFFQSAMRVCSSLRDLELAYQVHGLLNTGDNRKFIGPDPRRNFYYSKFFSLLCLMEQIDVTLKWYKDLIPSVFFPHSQTLIDLLQALDVANRLEMIPQIWKDSKEYGHTFRSDLKEEILMLMARDQHPPELQAAFADCAADIKSEWPANSLNYIAILFLRAGRTQEAWKMLGLFRKHNKIPRNELLNEFMDSAKASSSPAQAVEVVKLANSFS 4y49 A 3.95 BS01 G4P A 1 R437 K468 R400 K431 P12945 AAKIALKKYNQYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIESASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLAEQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKNKRKETEAKSVAAYPSDQDNDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHDPILKKVVTKSLEKEYSENFPLNEISNNSFDWLNFYQEKFKNDINGLLFLYRYRDDVPGSSNLKEMIISSLSPLEPHSQNEILQYY 4y49 B 3.95 BS01 III E 1 E26 Y28 T116 Y180 Y181 E25 Y27 T76 Y140 Y141 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNF 4y49 B 3.95 BS02 CMC B 1 S117 L118 S119 V120 R125 R126 M127 G128 I129 A130 E131 R159 A160 L164 Y165 T168 S77 L78 S79 V80 R85 R86 M87 G88 I89 A90 E91 R119 A120 L124 Y125 T128 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNF 4y49 C 3.95 BS01 ACO C 1 T26 E94 F95 L96 G97 V98 R103 H104 K105 S106 G108 S109 W141 T24 E75 F76 L77 G78 V79 R84 H85 K86 S87 G89 S90 W122 2.3.1.- Q08689 RDICTLDNVYANNLGMLTKLAHVTVPNLYQDAFFSALFAKDVHFTQMAYYSEIPVGGLVAKLVPKELSLKGIQIEFLGVLPNYRHKSIGSKLLKFAEDKCSECHQHNVFVYLPAVDDLTKQWFIAHGFEQVGETVNNFIKGVNGDEQDAILLKKHI 4y49 G 3.95 BS01 G4P G 1 L406 R437 L368 R399 P12945 AAKIALKKYNYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIESASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLAQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKNKRKETEAKSVAAYPSDQDNDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHPFDPILKKVVTKSLEKEYSENFPLNEISNNSFDWLNFYQEKFGKNDINGLLFLYRYRDDVPGSSNLKEMIISSLSPLEPHSQNEILQYY 4y49 H 3.95 BS01 III K 1 E26 Y28 T116 S117 Y180 Y181 E25 Y27 T76 S77 Y140 Y141 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNF 4y49 H 3.95 BS02 CMC H 1 S117 L118 S119 V120 R125 R126 M127 G128 A130 E131 V154 N158 R159 A160 A161 L164 T168 S77 L78 S79 V80 R85 R86 M87 G88 A90 E91 V114 N118 R119 A120 A121 L124 T128 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNF 4y49 I 3.95 BS01 ACO I 1 T26 V27 E94 F95 L96 G97 V98 R103 H104 K105 S106 G108 S109 W141 T24 V25 E74 F75 L76 G77 V78 R83 H84 K85 S86 G88 S89 W121 2.3.1.- Q08689 RDICTLDNVYANNLGMLTKLAHVTVPNLYQDAFFSALFAKDVHFTQMAYYSEIPVGGLVAKLVPKLSLKGIQIEFLGVLPNYRHKSIGSKLLKFAEDKCSECHQHNVFVYLPAVDDLTKQWFIAHGFEQVGETVNNFIKGVNGDEQDAILLKKHI 4y49 M 3.95 BS01 G4P M 1 K360 L406 R437 K322 L368 R399 P12945 AAKIALKKYNYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIESASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLAQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKNKRKETEAKSVAAYPSDQDNDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHFDPILKKVVTKSLEKEYSENFPLNEISNNSFDWLNFYQEKFGKNDINGLLFLYRYRDDVPGSSNLKEMIISSLSPLEPHSQNEILQYY 4y49 N 3.95 BS01 III Q 1 E26 Y28 T116 S117 H153 Y180 E25 Y27 T76 S77 H113 Y140 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNF 4y49 N 3.95 BS02 CMC N 1 L24 S117 L118 S119 V120 R125 R126 M127 G128 A130 E131 V154 A160 A161 L164 Y165 T168 L23 S77 L78 S79 V80 R85 R86 M87 G88 A90 E91 V114 A120 A121 L124 Y125 T128 2.3.1.88 P07347 PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNF 4y49 O 3.95 BS01 ACO O 1 T26 I93 E94 F95 L96 G97 V98 H104 K105 S106 G108 S109 W141 T24 I74 E75 F76 L77 G78 V79 H83 K84 S85 G87 S88 W120 2.3.1.- Q08689 RDICTLDNVYANNLGMLTKLAHVTVPNLYQDAFFSALFAKDVHFTQMAYYSEIPVGGLVAKLVPKELSLKGIQIEFLGVLPNHKSIGSKLLKFAEDKCSECHQHNVFVYLPAVDDLTKQWFIAHGFEQVGETVNNFIKGVNGDEQDAILLKKHI 4zf6 A 2.77 BS01 HEM A 1 K69 L86 V87 W96 F107 F261 A264 G265 T268 L272 T327 A328 F331 P392 F393 G394 R398 C400 I401 G402 F405 A406 K69 L86 V87 W96 F107 F261 A264 G265 T268 L272 T327 A328 F331 P392 F393 G394 R398 C400 I401 G402 F405 A406 1.14.14.1,1.6.2.4 P14779 27267136 TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGLVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDIAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKQQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHVTTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPS 4zf8 A 2.77 BS02 MYT A 1 V87 L181 I263 A264 T268 A328 V87 L181 I263 A264 T268 A328 1.14.14.1,1.6.2.4 P14779 27267136 TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGLVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDIAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKQQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHVTTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPS 4zfb A 2.84 BS02 PLM A 1 V26 Y51 V78 V87 Q188 P329 A330 L437 T438 V26 Y51 V78 V87 Q188 P329 A330 L437 T438 1.14.14.1,1.6.2.4 P14779 27267136 TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGLVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDIAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKQQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHVTTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPS 5aaq A BS01 ZN A 1 C422 C425 H440 H444 C33 C36 H51 H55 Q13137 27370208 SPLSIKKCPICKADDICDHTLEQQQMQPLCFNCPICDKIFPATEKQIFEDHVFCHSL 5aaz A BS01 ZN A 1 C498 C501 H514 C518 C9 C12 H25 C29 Q96CV9 27370208 SRNIPIHSCPKCGEVLPDIDTLQIHVMDCII 5abs A 1.74 BS01 ZN A 1 E643 K646 E47 K50 Q96B97 27353366 GHMEPAASSQAAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKAL 5abs A 1.74 BS02 ZN A 2 E624 D628 E28 D32 Q96B97 27353366 GHMEPAASSQAAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKAL 5b2n A 1.58 BS01 RET A 1 Y96 W99 I103 L106 M135 G139 S160 T161 F164 W201 Y204 P205 Y208 S234 K235 Y95 W98 I102 L105 M134 G138 S159 T160 F163 W200 Y203 P204 Y207 S233 K234 W8VZW3 KNIESLFDYSAGQFEFIDHLLTMGVGVHFAALIFFLVVSQFVAPKYRIATALSCIVMVSAGLILNSQAVMWTDAYAYVDGSYQLQDLTFSNGYRYVNWMATIPCLLLQLLIVLNLKGKELFSTATWLILAAWGMIITGYVGQLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNRATMLGGTDSTITKVFWLMMFAWTLYPIAYLVPAFMNNADGVVLRQLLFTIADISSKVIYGLMITYIAIQQSAAAGYVPAQQALGR 5b2n A 1.58 BS02 CL A 1 A61 W99 K235 A60 W98 K234 W8VZW3 KNIESLFDYSAGQFEFIDHLLTMGVGVHFAALIFFLVVSQFVAPKYRIATALSCIVMVSAGLILNSQAVMWTDAYAYVDGSYQLQDLTFSNGYRYVNWMATIPCLLLQLLIVLNLKGKELFSTATWLILAAWGMIITGYVGQLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNRATMLGGTDSTITKVFWLMMFAWTLYPIAYLVPAFMNNADGVVLRQLLFTIADISSKVIYGLMITYIAIQQSAAAGYVPAQQALGR 5b72 A 1.98 BS01 OSM A 1 T23 I24 T25 T23 I24 T25 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEASDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDSRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQKKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKMSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 5b72 A 1.98 BS03 HEM A 1 M101 G104 Q105 D108 D112 A114 E258 Q259 T344 F347 R348 G350 H351 F380 L417 I436 R440 M101 G104 Q105 D108 D112 A114 E258 Q259 T344 F347 R348 G350 H351 F380 L417 I436 R440 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEASDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDSRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQKKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKMSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 5bmv B 2.50 BS02 VLB C 1 P175 K176 V177 D179 Y210 F214 T220 P222 T223 Y224 L227 P173 K174 V175 D177 Y208 F212 T218 P220 T221 Y222 L225 P02554 26660762 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 5bmv C 2.50 BS01 GTP C 1 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 G10 Q11 A12 Q15 D98 A99 A100 N101 S140 G143 G144 T145 G146 I171 V177 T179 E183 N206 Y224 N228 P81947 26660762 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5bmv C 2.50 BS03 VLB C 1 P325 N329 I332 F351 V353 I355 P325 N329 I332 F351 V353 I355 P81947 26660762 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 5bmv F 2.50 BS01 ACP F 1 K74 I148 Q183 K184 Y185 L186 K198 D200 R202 R222 L240 T241 N242 D318 E331 N333 K74 I128 Q155 K156 Y157 L158 K170 D172 R174 R194 L212 T213 N214 D288 E301 N303 E1BQ43 26660762 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTNTDEREVFLAAYNRRREGREGNVWIAKGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLADTSIFIKLHHHHHH 5buo A 2.31 BS01 III B 1 L398 E399 I402 L472 L89 E90 I93 L163 P05067 ENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKE 5buo A 2.31 BS04 ZN A 3 D429 H458 D120 H149 P05067 ENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKE 5buo A 2.31 BS05 MG A 1 H436 H439 H127 H130 P05067 ENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKE 5buo A 2.31 BS06 SGN A 1 R411 P412 R413 H414 R102 P103 R104 H105 P05067 ENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKE 5bwl A 1.55 BS01 III B 1 A86 Y102 R105 I142 V221 W222 F223 G224 E225 N226 L227 L232 Y255 M259 F260 A51 Y67 R70 I107 V186 W187 F188 G189 E190 N191 L192 L197 Y220 M224 F225 3.5.1.- Q9NXA8 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 5bwl A 1.55 BS03 MCM B 1 R71 F223 V254 Y255 R36 F188 V219 Y220 3.5.1.- Q9NXA8 PSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 5bwn A 1.94 BS01 III B 1 A146 S149 T150 I154 D156 F157 R158 E177 F180 E181 L199 N229 I230 D231 H248 I291 V292 F293 F294 G295 E296 P297 L298 E323 V324 E325 P326 A26 S29 T30 I34 D36 F37 R38 E57 F60 E61 L79 N109 I110 D111 H128 I171 V172 F173 F174 G175 E176 P177 L178 E203 V204 E205 P206 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5bwo A 2.38 BS01 III B 1 Y175 E177 E181 H248 V292 F293 F294 G295 E296 P297 L298 E323 V324 E325 P326 Y55 E57 E61 H128 V172 F173 F174 G175 E176 P177 L178 E203 V204 E205 P206 3.5.1.- Q9NTG7 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKL 5c2o A 2.35 BS03 TTP A 1 R21 T23 T42 G43 Y44 G46 G47 A49 D50 N53 N75 Q79 R17 T19 T38 G39 Y40 G42 G43 A45 D46 N49 N71 Q75 Q8DSE5 LSWQDYFMANAELISKRSTCNRAYVGAVLVKNNRIIATGYNGGVADTDNCDDVGHEMEDGHCIRTVHAEMNALIQCAKEGISANNTEIYVTHFPCINCTKALLQAGVKKITYNTAYRIHPFAIELMTQKEVEYVQHDVPRVKLG 5c6x A 1.50 BS01 CO A 1 Q8 H65 E117 Q5 H62 E105 D1A230 MSRVQLALRVPDLEASIGFYSKLFGTGPAKVRPGYANFAIAEPPLKLVLIEGAGEDATRLDHLGVEVEDSAQVGHAARRLKESGLATVEENDKVWVTGPGGEPWEVYVV 5c89 A 1.65 BS01 4YT A 1 I652 F653 V657 V662 Y707 N708 F714 I26 F27 V31 V36 Y81 N82 F88 P55201 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5cf0 A 1.80 BS01 FJS A 1 N51 A55 K58 D93 I96 G97 M98 L107 F138 V150 W162 T184 V186 N35 A39 K42 D77 I80 G81 M82 L91 F122 V134 W146 T168 V170 P07900 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 5cfv A 1.80 BS01 MAL A 1 D14 K15 W62 A63 D65 R66 E111 E153 P154 Y155 F156 W230 W340 D13 K14 W61 A62 D64 R65 E110 E152 P153 Y154 F155 W229 W339 P0AEX9 IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQAALYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTNAAAAYQNYIAKSQASEAFTLADGLKTTINTNLQAGTCFAGGATAVTAADKVSGKYGDAEIGGTAPNCTITYTFKSSGVSNKLTSTKIVMNVSETGILTKNSGTDTPVELLPQSFVASG 5cg4 A 2.50 BS01 6UV A 1 P1 M2 K32 P33 Y36 S63 I64 K66 F113 P1 M2 K32 P33 Y36 S63 I64 K66 F113 5.3.2.1,5.3.3.12 P14174 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 5cgq B 1.18 BS02 TRP B 1 K87 E109 T110 G111 A112 G113 Q114 H115 L166 T190 G233 F306 K86 E108 T109 G110 A111 G112 Q113 H114 L165 T189 G232 F305 4.2.1.20 P0A2K1 TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDIL 5dgm F 2.86 BS01 59Z F 1 Y10 K57 N59 R60 T63 S205 F206 F239 L344 K347 I348 Y3 K50 N52 R53 T56 S198 F199 F232 L337 K340 I341 2.5.1.10,2.5.1.1 P14324 26457482 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 5dgs F 2.62 BS01 5A7 F 1 Y10 G56 K57 Y58 N59 R60 T63 R113 S205 F206 F239 Q242 L344 K347 I348 K350 Y3 G49 K50 Y51 N52 R53 T56 R106 S198 F199 F232 Q235 L337 K340 I341 K343 2.5.1.10,2.5.1.1 P14324 26457482 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 5e8j A 2.35 BS01 SAH A 1 K180 G205 C206 G207 D227 I228 A260 D261 S262 Q284 F285 V286 Y289 M300 K14 G39 C40 G41 D61 I62 A94 D95 S96 Q118 F119 V120 Y123 M134 2.1.1.56 O43148 SRIFYLRNFNNWMKSVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKELLIDKFRDPQMCFDICSCQFVCHYSFESYEQADMMLRNACERLSPGGYFIGTTPNSFELIRRLEASETESFGNEIYTVKFQKKGDYPLFGCKYDFNLEGVVDVPEFLVYFPLLNEMAKKYNMKLVYKKTFLEFYEEKIKNNENKMLLKRMQALEPYPANESSKLVSEKVDDYEHAAKYMKNSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ 5e9j A 3.47 BS01 SAH A 1 K180 G205 C206 G207 D227 I228 D261 S262 Q284 F285 V286 Y289 K14 G39 C40 G41 D61 I62 D95 S96 Q118 F119 V120 Y123 2.1.1.56,2.1.1.56 O43148 SRIFYLRNFNNWMKSVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKELLIDKFRDPQMCFDICSCQFVCHYSFESYEQADMMLRNACERLSPGGYFIGTTPNSFELIRRLEASETESFGNEIYTVKFQKKGDYPLFGCKYDFNLEGVVDVPEFLVYFPLLNEMAKKYNMKLVYKKTFLEFYEEKIKNNENKMLLKRMQGGSGSKSEWEATSIYLVFAFEKQQ 5e9j B 3.47 BS01 SAH B 1 K180 G205 G207 D211 D227 I228 D261 S262 Q284 F285 V286 Y289 K14 G39 G41 D45 D61 I62 D95 S96 Q118 F119 V120 Y123 2.1.1.56,2.1.1.56 O43148 SRIFYLRNFNNWMKSVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKELLIDKFRDPQMCFDICSCQFVCHYSFESYEQADMMLRNACERLSPGGYFIGTTPNSFELIRRLEASETESFGNEIYTVKFQKKGDYPLFGCKYDFNLEGVVDVPEFLVYFPLLNEMAKKYNMKLVYKKTFLEFYEEKIKNNENKMLLKRMQGGSGSKSEWEATSIYLVFAFEKQQ 5eg4 A 1.32 BS02 5N7 A 1 H57 S96 N97 L99 D189 S190 C191 S195 V213 S214 W215 G216 S217 G219 C220 G226 H40 S78 N79 L81 D171 S172 C173 S177 V191 S192 W193 G194 S195 G196 C197 G204 3.4.21.4 P00760 27280436 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 5f38 B 1.90 BS01 COZ B 1 C88 L149 H157 M158 K221 S224 L229 L232 A235 F236 A244 G245 S248 G249 M289 A319 F320 H349 C88 L149 H157 M158 K219 S222 L227 L230 A233 F234 A242 G243 S246 G247 M287 A317 F318 H347 2.3.1.9 P76461 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTKTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERL 5f38 D 1.90 BS01 5UG D 1 C88 L149 H157 A244 S248 I250 M289 A319 F320 H349 C90 L151 H159 A246 S250 I252 M291 A321 F322 H351 2.3.1.9 P76461 ASMKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIER 5f38 C 1.90 BS01 5UG C 1 C88 L149 M158 F233 A241 S245 M286 A316 F317 H346 C90 L151 M160 F235 A243 S247 M288 A318 F319 H348 2.3.1.9 P76461 ASMKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERL 5fnb A 1.79 BS03 HEM A 1 R39 E40 L42 R43 T45 F46 P139 E140 P141 L165 L166 S168 H169 A172 A173 A174 D175 K176 V177 F186 L228 S230 R39 E40 L42 R43 T45 F46 P139 E140 P141 L165 L166 S168 H169 A172 A173 A174 D175 K176 V177 F186 L228 S230 1.11.1.16,1.11.1.7 O94753 27118867 ATCDDGRTTANAACCILFPILDDIQENLFDGAQCGEKVRESLRLTFHDAIGFSPTLGGGGADGSIIAFDTIETNFPANAGIDEIVSAQKPFVAKHNISAGDFIQFAGAVGVSNCPGGVRIPFFLGRPDAVAASPDHLVPEPFDSVDSILARMGDAGFSPAEVVWLLASHSIAAADKVDPSIPGMPFDSTPGVFDSQFFIETLLKGRLFPGTAANKGEAQSPLQGEIRLQSDHLLARDPQTACEWQSMVNNQPKIQNRFAATMSKMALLGQDKTKLIDCSDVIPTPPALVGAAHLPAGFSLSDVEQACAATPFPALTADPGPVTSVPPVP 5fnb B 1.79 BS03 HEM B 1 R39 E40 L42 R43 F46 P139 E140 P141 L165 L166 S168 H169 A172 A173 A174 F186 L228 S230 M262 R39 E40 L42 R43 F46 P139 E140 P141 L165 L166 S168 H169 A172 A173 A174 F178 L214 S216 M248 1.11.1.16,1.11.1.7 O94753 27118867 ATCDDGRTTANAACCILFPILDDIQENLFDGAQCGEKVRESLRLTFHDAIGFSPTLGGGGADGSIIAFDTIETNFPANAGIDEIVSAQKPFVAKHNISAGDFIQFAGAVGVSNCPGGVRIPFFLGRPDAVAASPDHLVPEPFDSVDSILARMGDAGFSPAEVVWLLASHSIAAAGMPFDSTPGVFDSQFFIETLLKGRLNKGEAQSPLQGEIRLQSDHLLARDPQTACEWQSMVNNQPKIQNRFAATMSKMALLGQDKTKLIDCSDVIPTPPALVGAAHLPAGFSLSDVEQACAATPFPALTADPGPVTSVPPVP 5g2g A 1.60 BS01 EQU A 1 Y16 D40 F86 M90 L99 D103 K116 W120 Y15 D39 F85 M89 L98 D102 K115 W119 P07445 27375051 NLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVEDPFGQPPIHGREQIAAFYRQGLGGGKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDVIDVMRFDEHGRIQTKQAYWSEVNLSVR 5g2g B 1.60 BS01 EQU B 1 Y16 D40 F86 V88 M90 L99 D103 K116 W120 Y14 D38 F84 V86 M88 L97 D101 K114 W118 P07445 27375051 LPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVEDPFGQPPIHGREQIAAFYRQGLGGGKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDVIDVMRFDEHGRIQTKQAYWSEVNLSVR 5hpy A 2.40 BS01 GDP B 1 R235 R340 R32 R137 Q13459 27363609 GHFGVCVSVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQL 5hpy B 2.40 BS03 GDP B 1 A15 C16 G17 K18 T19 C20 F30 Y34 K118 D120 L121 S160 A161 K162 A13 C14 G15 K16 T17 C18 F28 Y32 K116 D118 L119 S158 A159 K160 P61586 27363609 AIRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 5hpy F 2.40 BS02 GDP F 1 A15 G17 K18 T19 C20 F30 Y34 K118 D120 L121 S160 A161 K162 A13 G15 K16 T17 C18 F28 Y32 K116 D118 L119 S158 A159 K160 P61586 27363609 AIRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 5hpy F 2.40 BS04 MG F 2 T19 T37 E40 Y42 D59 T17 T35 E38 Y40 D57 P61586 27363609 AIRKKLVIVGDGACGKTCLLIVNSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 5hrm A 2.05 BS01 MN A 1 E201 H317 H389 E407 H475 E114 H230 H302 E320 H388 A0A077JBW9 27353520 QVVIGPGDRPETGLQGQTTIEDVVSGRSKLPYHAGVRLVGRTDIWNRGGNLQLSWVDQCAYVSTFKQAGPITANSRSALFLREPAGVAVIDVRDPRAPKPVRLLRDRGSIDAVETMHAIAAPGRKVLVAGAYSGGIAGRGEEDAAWLSIYDASNCLNPKLQSEFKWPANIHMVTISPNGRRVYGTEVVPGLGSGKGGLHVLDISDMKRPRYLGRFGVTRPNGLTAGFTPHEVSISHDERRIYAAVLASETGDVPVGASILASDGDVPVENGSVYILDNSDIVDGRSQPKMRLVGEAKQGGFHSVVPASINGVPHLVGAAELGACPGTWPRIINIADEKNPKIVGEFKLQMNIKENCDAIRFTPRKEDPYASFIPIPDITARLGAVGSHFNDVDDARNTRLGLFPFFAGGVRIVDLRDPTKPVEVGYYKPGANPDTPLSGNGLNWTGLNDQVTDGCMSHVRYVPESGHIWFACVTTGFHVVELNPDLRARLGFPT 5hrm A 2.05 BS02 MN A 2 E201 H258 H317 E114 H171 H230 A0A077JBW9 27353520 QVVIGPGDRPETGLQGQTTIEDVVSGRSKLPYHAGVRLVGRTDIWNRGGNLQLSWVDQCAYVSTFKQAGPITANSRSALFLREPAGVAVIDVRDPRAPKPVRLLRDRGSIDAVETMHAIAAPGRKVLVAGAYSGGIAGRGEEDAAWLSIYDASNCLNPKLQSEFKWPANIHMVTISPNGRRVYGTEVVPGLGSGKGGLHVLDISDMKRPRYLGRFGVTRPNGLTAGFTPHEVSISHDERRIYAAVLASETGDVPVGASILASDGDVPVENGSVYILDNSDIVDGRSQPKMRLVGEAKQGGFHSVVPASINGVPHLVGAAELGACPGTWPRIINIADEKNPKIVGEFKLQMNIKENCDAIRFTPRKEDPYASFIPIPDITARLGAVGSHFNDVDDARNTRLGLFPFFAGGVRIVDLRDPTKPVEVGYYKPGANPDTPLSGNGLNWTGLNDQVTDGCMSHVRYVPESGHIWFACVTTGFHVVELNPDLRARLGFPT 5hs6 A 2.02 BS01 NAD A 1 G16 R19 G20 I21 D40 K41 C61 D62 V63 N89 A90 G91 L113 I139 S140 S141 Y154 K158 P184 G185 N186 I187 T189 P190 L191 W192 G13 R16 G17 I18 D37 K38 C58 D59 V60 N86 A87 G88 L110 I136 S137 S138 Y151 K155 P181 G182 N183 I184 T186 P187 L188 W189 1.1.1.- Q9BPX1 27362750 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKAPSG 5hs6 A 2.02 BS02 J3Z A 1 H93 Q148 Y154 L191 W192 L195 M199 T205 H90 Q145 Y151 L188 W189 L192 M196 T202 1.1.1.- Q9BPX1 27362750 GTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKAPSG 5hu9 A 1.53 BS01 66K A 1 L248 V256 A269 V270 K271 E286 M290 I293 L298 V299 I313 T315 F317 M318 G321 I360 H361 L370 V379 A380 D381 F382 L24 V32 A45 V46 K47 E62 M66 I69 L74 V75 I89 T91 F93 M94 G97 I136 H137 L146 V155 A156 D157 F158 2.7.10.2 P00519 27322145 AMGSSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 5hu9 A 1.53 BS02 66K A 2 R386 L387 M388 F401 I403 A412 Y413 Y449 R162 L163 M164 F172 I174 A183 Y184 Y220 2.7.10.2 P00519 27322145 AMGSSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 5i6k A 1.07 BS04 NO2 A 2 W265 T267 G268 K269 N272 W259 T261 G262 K263 N266 1.7.2.1 P25006 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5i6k A 1.07 BS05 NO2 A 3 R250 D251 R244 D245 1.7.2.1 P25006 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5i6k A 1.07 BS06 NO2 A 4 T171 R240 T165 R234 1.7.2.1 P25006 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5i6k A 1.07 BS07 NO2 A 5 K125 T127 K119 T121 1.7.2.1 P25006 VDISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPASM 5i6l A 1.08 BS06 NO2 A 4 R250 R253 N307 E310 R243 R246 N300 E303 1.7.2.1 P25006 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5i6m A 1.09 BS08 NO2 A 5 G225 A226 T228 H231 G218 A219 T221 H224 1.7.2.1 P25006 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5i6n A 1.22 BS04 NO2 A 1 D188 K194 D181 K187 1.7.2.1 P25006 DISTLPRVKVDLVKPPFVHAHDQVAKTGPRVVEFTMTIEEKKLVIDREGTEIHAMTFNGSVPGPLMVVHENDYVELRLINPDTNTLLHNIDFHAATGALGGGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTYDKIYYVGEQDFYVPKDEAGNYKKYETPGEAYEDAVKAMRTLTPTHIVFNGAVGALTGDHALTAAVGERVLVVHSQANRDTRPHLIGGHGDYVWATGKFRNPPDLDQETWLIPGGTAGAAFYTFRQPGVYAYVNHNLIEAFELGAAGHFKVTGEWNDDLMTSVVKPAS 5icm A 1.68 BS02 F45 A 1 H93 P96 S141 V143 Q148 A149 Q150 Y154 N186 W192 L195 H89 P92 S137 V139 Q144 A145 Q146 Y150 N182 W188 L191 1.1.1.- Q9BPX1 27362750 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKPSG 5icm A 1.68 BS03 GLC A 1 G20 W188 T189 P190 E193 G16 W184 T185 P186 E189 1.1.1.- Q9BPX1 27362750 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKPSG 5ikd A 1.11 BS01 HEM A 1 E162 F164 F166 L167 D168 G169 I170 A171 L219 Q221 V253 R255 H304 I305 T308 R309 R311 I330 R332 L357 F370 L373 Q374 I397 I398 V426 E160 F162 F164 L165 D166 G167 I168 A169 L217 Q219 V251 R253 H302 I303 T306 R307 R309 I328 R330 L355 F368 L371 Q372 I395 I396 V424 1.11.1.19 I2DBY1 SLNTIDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNLGDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHEMFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPNLSAGANSIMRSGIPYGPEVTSAESASNTTTQERGLAGVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNNGQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA 5ikg A 1.95 BS01 HEM A 1 E162 F164 F166 L167 D168 G169 I170 A171 L219 Q221 V253 R255 H304 I305 T308 R309 R311 R332 F359 F370 L373 I397 I398 E159 F161 F163 L164 D165 G166 I167 A168 L216 Q218 V250 R252 H301 I302 T305 R306 R308 R329 F356 F367 L370 I394 I395 1.11.1.19 I2DBY1 LNTIDIQGDILVGMHKQKQLFYFFAINDPATFKTHLASDIAPVVASVTQLSNVATQPLVALNIAFSNTGLLALGVTDNLGDSLFANGQAKDATSFKESTSSWVPQFAGTGIHGVIILASDTTDLIDQQVASIESTFGSSISKLYSLSASIRPGNEAGHEMFGFLDGIAQPAINGFNTPLPGQNIVDAGVIITGATNDPITRPSWAVGGSFLAFRQLEQLVPEFNKYLLDNAPAGSGSLQARADLLGARMVGRWKSGAPIDLTPTADDPALGADAQRNNNFTYSHAGFDLGSDQSHCPFSAHIRKTRPRADLGGSLTPPNLSAGANSIMRSGIPYGPEVTSAESASNTTTQERGGAFVAYQAQLSQGFHFLQQTWADNANFPPGKTPATVGLDPIIGQNNGQPRVVNGLLPSNSSASLSIPQFVVSHGGEYFFSPPISAIGGRLSA 5iw4 A 2.60 BS02 NAD A 1 A128 C130 I132 F160 Q192 W194 F196 S199 M201 T239 V240 A241 A129 C131 I133 F161 Q193 W195 F197 S200 M202 T240 V241 A242 3.6.1.22 D6JHV3 SMDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEY 5iw4 B 2.60 BS02 NAD B 1 A128 C130 F160 W194 F196 M201 T239 V240 A241 A129 C131 F161 W195 F197 M202 T240 V241 A242 3.6.1.22 D6JHV3 SMDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE 5iw5 B 2.70 BS02 NMN B 1 R69 C130 W194 S199 M201 P235 P236 T239 V240 A241 R68 C129 W193 S198 M200 P234 P235 T238 V239 A240 3.6.1.22 D6JHV3 DRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE 5iw5 A 2.70 BS02 NMN A 1 R69 F160 W194 P197 S199 M201 P236 T239 A241 R69 F157 W191 P194 S196 M198 P233 T236 A238 3.6.1.22 D6JHV3 MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE 5j6g A 3.30 BS01 III F 1 M5 Y7 Y59 R62 E63 R66 N70 S73 F74 V76 S77 T80 L81 Y84 W97 Y99 Y116 Y123 T143 K146 W147 Y155 Y156 Y159 W167 Y171 M5 Y7 Y59 R62 E63 R66 N70 S73 F74 V76 S77 T80 L81 Y84 W97 Y99 Y116 Y123 T143 K146 W147 Y155 Y156 Y159 W167 Y171 P01898 GSHSMRYFETSVSRPGLGEPRFIIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQEGPEYWERETQRAKGNEQSFHVSLRTLLGYYNQSESGSHTIQWMYGCKVGSDGRFLRGYLQYAYDGRDYIALNEDLKTWTAADVAAIITRRKWEQAGAAEYYRAYLEAECVEWLLRYLELGKETLLRTDPPKTHVTHHPGSEGDVTLRCWALGFYPADITLTWQLNGTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVYHEGLPEPLTLRWE 5j6h A 2.30 BS01 III F 1 M5 Y7 Y59 E63 R66 N70 S73 F74 V76 S77 Y84 W97 Y99 Y116 Y123 T143 W147 Y155 Y156 Y159 W167 Y171 M5 Y7 Y59 E63 R66 N70 S73 F74 V76 S77 Y84 W97 Y99 Y116 Y123 T143 W147 Y155 Y156 Y159 W167 Y171 P01898 GSHSMRYFETSVSRPGLGEPRFIIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQEGPEYWERETQRAKGNEQSFHVSLRTLLGYYNQSESGSHTIQWMYGCKVGSDGRFLRGYLQYAYDGRDYIALNEDLKTWTAADVAAIITRRKWEQAGAAEYYRAYLEAECVEWLLRYLELGKETLLRTDPPKTHVTHHPGEGDVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVYHEGLPEPLTLRWEP 5j6h A 2.30 BS02 NCA A 1 P47 R48 P47 R48 P01898 GSHSMRYFETSVSRPGLGEPRFIIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQEGPEYWERETQRAKGNEQSFHVSLRTLLGYYNQSESGSHTIQWMYGCKVGSDGRFLRGYLQYAYDGRDYIALNEDLKTWTAADVAAIITRRKWEQAGAAEYYRAYLEAECVEWLLRYLELGKETLLRTDPPKTHVTHHPGEGDVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVYHEGLPEPLTLRWEP 5jab A 1.65 BS01 6J4 A 1 L23 H36 V38 A39 V40 G41 I54 T55 G58 Q60 K61 R67 L23 H36 V38 A39 V40 G41 I54 T55 G58 Q60 K61 R67 P9WLL7 27364382 MAMVNTTTRLSDDALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPKTHIARVITTGGSQKAVNADRSGLAVLSQVDGARWLSLEGRAAVNSDIDAVRDAELRYAQRYRTPRPNPRRVVIEVQIERVLGSADLLD 5jab A 1.65 BS02 6J4 B 1 M1 G78 A79 W81 M1 G78 A79 W81 P9WLL7 27364382 MAMVNTTTRLSDDALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPKTHIARVITTGGSQKAVNADRSGLAVLSQVDGARWLSLEGRAAVNSDIDAVRDAELRYAQRYRTPRPNPRRVVIEVQIERVLGSADLLD 5jab B 1.65 BS01 6J4 A 1 R9 G78 A79 W81 R126 L128 R1 G70 A71 W73 R118 L120 P9WLL7 27364382 RLSDDALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPKTHIARVITTGGSQKAVNADRSGLAVLSQVDGARWLSLEGRAAVNSDIDAVRDAELRYAQRYRTPRPNPRRVVIEVQIERVLGSADLLD 5jab C 1.65 BS02 6J4 D 1 G78 A79 W81 R126 L128 G70 A71 W73 R118 L120 P9WLL7 27364382 RLSDDALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPKTHIARVITTGGSQKAVNADRSGLAVLSQVDGARWLSLEGRAAVNSDIDAVRDAELRYAQRYRTPRPNPRRVVIEVQIERVLGSADLLD 5jbq A 2.01 BS01 III B 1 E215 F218 I220 R223 V226 T228 G257 E259 F261 R262 L264 N273 V274 G275 V276 L277 E214 F217 I219 R222 V225 T227 G256 E258 F260 R261 L263 N272 V273 G274 V275 L276 P0CE47 27355833 KEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG 5jdu D 1.70 BS01 III C 1 E23 I24 G25 M26 P28 W29 S115 D116 Y117 H119 P120 C122 L129C Y134 K135 G136 R137 N159 Y184A M201 K202 P204 N205 R206 W207 E8 I9 G10 M11 P13 W14 S112 D113 Y114 H116 P117 C119 L129 Y134 K135 G136 R137 N154 Y180 M201 K202 P204 N207 R208 W209 3.4.21.5 P00734 27347732 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGAACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 5jea B 2.65 BS01 NUC R 1 L14 F84 R119 L177 L12 F82 R117 L175 P46948 27345150 RLEIYSPEGLRLDGRRWNELRRFESSINTHPHAADGSSYMEQGNNKIITLVKGPKEPRLKSQMDTSKALLNVSVNITKFSKFERSKSSHKNERRVLEIQTSLVRMFEKNVMLNIYPRTVIDIEIHVLEQDGGIMGSLINGITLALIDAGISMFDYISGISVGLYDTTPLLDTNSLEENAMSTVTLGVVGKSEKLSLLLVEDKIPLDRLENVLAIGIAGAHRVRDLMDEELRKHAQKRVSNASA 5jea G 2.65 BS01 NUC R 1 T79 R110 T79 R110 Q08285 27345150 DSMSTFIFPGDSFPVDPTTPVKLGPGIYCDPNTQEIRPVNTGVLHVSAKGKVQTAYIDYSSKRYIPSVNDFVIGVIIGTFSDSYKVSLQNFSSSVSLSYMAFPNASKKNRPTLQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFARQLLFNNDFPLLKVLAAHTKFEVAIGLNGKIWVKCEELSNTLACYRTIMECCQKNDTAAFKDIAKRQFKEIL 5jea H 2.65 BS01 NUC R 1 R123 K125 M137 F177 Q178 D179 R73 K75 M87 F127 Q128 D129 P38792 27345150 DSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETGDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLLNAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNGYIWLRKTSQMDLARDTITRLEEESSWQIYSDENDPSISNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESIGSDILTAEKMR 5jea J 2.65 BS01 NUC R 1 K22 F24 R37 D543 P544 G546 C547 V548 D549 I550 N551 D552 Y595 K599 R600 Y654 L696 S698 E700 K702 K718 V727 E728 M731 L732 R753 H755 T810 R811 M813 A815 A816 H831 Y839 H841 T843 S844 R847 R889 R896 K14 F16 R29 D491 P492 G494 C495 V496 D497 I498 N499 D500 Y543 K547 R548 Y602 L644 S646 E648 K650 K661 V670 E671 M674 L675 R696 H698 T753 R754 M756 A758 A759 H774 Y782 H784 T786 S787 R790 R832 R839 3.1.13.-,3.1.26.- Q08162 27345150 RRKRLADGLSVTQKVFVRSRNGGATKIVREHYLRSDIPCLSRSCTKCPQIVVPDAQNELPKFILSDSPLELSAPIGKHYVVLDTNVVLQAIDLLENPNCFFDVIVPQIVLDEVRNKSYPVYTRLRTLCRDSDDHKRFIVFHNEFSEHTFVERLPNETINDRNNRAIRKTCQWYSEHLKPYDINVVLVTNDRLNREAANIITKSLVQYIELLPNADDIRDSIPQDFTFPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLPRFSKPVLIVGQKNLNRAFNGDQVIVELLPQSEWKAPSSIVLDSEHFDISDKQRRLLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCLPKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDINDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELTMGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSEEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNNESTETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKLTFVPTNSDKPRDVYVFDKVEVQVRSVMDELLLK 5jja A 2.35 BS01 III C 1 K183 H187 Y190 R197 S230 N233 G234 F235 A236 K240 H243 K141 H145 Y148 R155 S188 N191 G192 F193 A194 K198 H201 Q13362 27350047 GIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLY 5jja B 2.35 BS01 III D 1 D180 H187 Y190 L194 R197 S230 N233 G234 F235 A236 K240 H243 D137 H144 Y147 L151 R154 S187 N190 G191 F192 A193 K197 H200 Q13362 27350047 IRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYR 5jqh A 3.20 BS01 CAU A 1 W1109 D1113 V1114 F1193 S1203 S1204 S1207 W1286 F1289 F1290 N1293 N1312 Y1316 W188 D192 V193 F272 S282 S283 S286 W334 F337 F338 N341 N360 Y364 3.2.1.17 P07550 NIFEMLRIDEFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYAADEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLDKFALKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLR 5jqh A 3.20 BS02 CLR A 1 I1055 C1077 L1080 V1081 I134 C156 L159 V160 3.2.1.17 P07550 NIFEMLRIDEFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYAADEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLDKFALKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLR 5jqh B 3.20 BS01 CAU B 1 W1109 D1113 V1114 V1117 F1193 S1203 F1289 F1290 N1293 Y1308 N1312 Y1316 W197 D201 V202 V205 F281 S291 F347 F348 N351 Y366 N370 Y374 3.2.1.17 P07550 GNIFEMLRIDVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYAADEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLIDKFALKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRR 5jqh B 3.20 BS02 CLR B 1 I1055 L1080 V1081 I143 L168 V169 3.2.1.17 P07550 GNIFEMLRIDVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYAADEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLIDKFALKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRR 5jr1 H 1.60 BS01 ZN H 1 D100 E100I D106 E115 27299673 EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTTDYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCARTGKYYDFWSGYPPGEEYFQDWGRGTLVTVSSASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 5ju6 A 2.20 BS01 BGC A 1 V74 D92 L141 R156 K189 H190 R200 M242 Y245 D277 W278 S447 E505 V54 D72 L121 R136 K169 H170 R180 M222 Y225 D257 W258 S427 E485 3.2.1.21 Q8TGI8 NLAYSPPFYPSPWANGQGDWAEAYQKAVQFVSQLTLAEKVNLTTGTGWEQDRCVGQVGSIPRLGFPGLCMQDSPLGVRDTDYNSAFPAGVNVAATWDRNLAYRRGVAMGEEHRGKGVDVQLGPVAGPLGRSPDAGRNWEGFAPDPVLTGNMMASTIQGIQDAGVIACAKHFILYEQEHFRQGAQDGYDISDSISANADDKTMHELYLWPFADAVRAGVGSVMCSYNQVNNSYACSNSYTMNKLLKSELGFQGFVMTDWGGHHSGVGSALAGLDMSMPGDIAFDSGTSFWGTNLTVAVLNGSIPEWRVDDMAVRIMSAYYKVGRDRYSVPINFDSWTLDTYGPEHYAVGQGQTKINEHVDVRGNHAEIIHEIGAASAVLLKNKGGLPLTGTERFVGVFGKDAGSNPWGVNGCSDRGCDNGTLAMGWGSGTANFPYLVTPEQAIQREVLSRNGTFTGITDNGALAEMAAAASQADTCLVFANADSGEGYITVDGNEGDRKNLTLWQGADQVIHNVSANCNNTVVVLHTVGPVLIDDWYDHPNVTAILWAGLPGQESGNSLVDVLYGRVNPGKTPFTWGRARDDYGAPLIVKPNNGKGAPQQDFTEGIFIDYRRFDKYNITPIYEFGFGLSYTTFEFSQLNVQPINAPPYTPASGFTKAAQSFGQPSNASDNLYPSDIERVPLYIYPWLNSTDLKASANDPDYGLPTEKYVPPNATNGDPQPIDPAGGAPGGNPSLYEPVARVTTIITNTGKVTGDEVPQLYVSLGGPDDAPKVLRGFDRITLAPGQQYLWTTTLTRRDISNWDPVTQNWVVTNYTKTIYVGNSSRNLPLQAPLKPYP 5ju6 C 2.20 BS01 BGC C 1 D92 R98 L141 R156 K189 H190 R200 M242 Y245 D277 W278 S447 E505 D72 R78 L121 R136 K169 H170 R180 M222 Y225 D257 W258 S427 E485 3.2.1.21 Q8TGI8 NLAYSPPFYPSPWANGQGDWAEAYQKAVQFVSQLTLAEKVNLTTGTGWEQDRCVGQVGSIPRLGFPGLCMQDSPLGVRDTDYNSAFPAGVNVAATWDRNLAYRRGVAMGEEHRGKGVDVQLGPVAGPLGRSPDAGRNWEGFAPDPVLTGNMMASTIQGIQDAGVIACAKHFILYEQEHFRQGAQDGYDISDSISANADDKTMHELYLWPFADAVRAGVGSVMCSYNQVNNSYACSNSYTMNKLLKSELGFQGFVMTDWGGHHSGVGSALAGLDMSMPGDIAFDSGTSFWGTNLTVAVLNGSIPEWRVDDMAVRIMSAYYKVGRDRYSVPINFDSWTLDTYGPEHYAVGQGQTKINEHVDVRGNHAEIIHEIGAASAVLLKNKGGLPLTGTERFVGVFGKDAGSNPWGVNGCSDRGCDNGTLAMGWGSGTANFPYLVTPEQAIQREVLSRNGTFTGITDNGALAEMAAAASQADTCLVFANADSGEGYITVDGNEGDRKNLTLWQGADQVIHNVSANCNNTVVVLHTVGPVLIDDWYDHPNVTAILWAGLPGQESGNSLVDVLYGRVNPGKTPFTWGRARDDYGAPLIVKPNNGKGAPQQDFTEGIFIDYRRFDKYNITPIYEFGFGLSYTTFEFSQLNVQPINAPPYTPASGFTKAAQSFGQPSNASDNLYPSDIERVPLYIYPWLNSTDLKASANDPDYGLPTEKYVPPNATNGDPQPIDPAGGAPGGNPSLYEPVARVTTIITNTGKVTGDEVPQLYVSLGGPDDAPKVLRGFDRITLAPGQQYLWTTTLTRRDISNWDPVTQNWVVTNYTKTIYVGNSSRNLPLQAPLKPYP 5jvx A 1.70 BS01 6O0 A 1 A1 T2 N40 V41 E42 A1 T2 N40 V41 E42 P02883 27364343 ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTNGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMNFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA 5jvx A 1.70 BS02 6O0 A 2 K49 W51 F80 G81 T85 L87 K106 K49 W51 F80 G81 T85 L87 K106 P02883 27364343 ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTNGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMNFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA 5jvx A 1.70 BS03 6O0 A 3 R82 P83 K106 T150 R82 P83 K106 T150 P02883 27364343 ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTNGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMNFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA 5jvx A 1.70 BS05 6O0 A 5 F172 R175 F172 R175 P02883 27364343 ATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTNGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMNFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTA 5k0y P 5.80 BS01 NUC N 1 R57 S58 N60 K61 L62 I63 R64 R67 T103 K106 T107 R113 L119 E120 R182 R183 L184 T185 P186 Q187 A188 R192 I230 R234 R52 S53 N55 K56 L57 I58 R59 R62 T98 K101 T102 R108 L114 E115 R177 R178 L179 T180 P181 Q182 A183 R187 I225 R229 G1T2G4 27373335 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNV 5k0y S 5.80 BS01 NUC N 1 R81 F82 Y96 F275 D276 V277 K279 P280 G281 V291 S333 F335 G351 R362 A363 D364 R365 R30 F31 Y45 F224 D225 V226 K228 P229 G230 V240 S282 F284 G300 R311 A312 D313 R314 27373335 QATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIR 5k0y S 5.80 BS02 III d 1 Q202 I205 E210 A213 Y217 E230 P233 I234 P236 I237 S238 Y243 N244 E246 V247 Y251 Q151 I154 E159 A162 Y166 E179 P182 I183 P185 I186 S187 Y192 N193 E195 V196 Y200 27373335 QATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIR 5k0y U 5.80 BS01 NUC F 1 I128 G129 R130 A131 G132 Q137 R204 I115 G116 R117 A118 G119 Q124 R191 G1TFM5 27373335 TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR 5k0y V 5.80 BS01 NUC F 1 K125 K126 K51 K52 G1T8A2 27373335 KVHGSLARVGKVRGQTLKVAKQEKKKKRTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS 5k0y c 5.80 BS01 NUC F 1 G38 K39 A40 Q98 A133 R137 G1 K2 A3 Q61 A96 R100 27373335 GKAGDKEWLPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGAALKDKVLKIMPVQKQTQAGQRTRFKAFVAIGDYNGHVGLGMKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVRCKVTGRCGSVLVRLIPAPRGTGIISAPVPKKLLLMAGIDDCYTSAGGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHT 5k0y g 5.80 BS01 NUC F 1 T53 R54 T55 Q56 K90 R94 S104 K108 R116 R117 G121 R124 F125 R143 R146 K148 T53 R54 T55 Q56 K90 R94 S104 K108 R116 R117 G121 R124 F125 R143 R146 K148 27373335 MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIVEPKDEILPTTPISEQK 5k0y k 5.80 BS01 NUC F 1 R42 E46 R41 E45 G1TFE8 27373335 TKKRRNNGRAKKGRGHVQPIRCTNCACCVPKDKAIKKFVIRNIVEAAAVRDISEVSVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPR 5k0y l 5.80 BS01 NUC F 1 E64 R66 R67 E60 R62 R63 G1TIB4 27373335 RVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRL 5k8f A 2.45 BS01 ATP A 1 T289 S292 K297 W334 G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 I539 R542 K640 T280 S283 K288 W325 G403 E404 P405 D427 T428 Y429 W430 M431 T432 D518 I530 R533 K631 6.2.1.1 J9VFT1 VHHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSGSTGKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f A 2.45 BS02 6R9 A 1 W334 I335 V411 G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 I539 R542 K640 W325 I326 V402 G403 E404 P405 D427 T428 Y429 W430 M431 T432 D518 I530 R533 K631 6.2.1.1 J9VFT1 VHHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSGSTGKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f B 2.45 BS01 MG B 1 M440 E442 M430 E432 6.2.1.1 J9VFT1 HHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSGSTGKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f B 2.45 BS02 ATP B 1 T289 G291 S292 T293 G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 I539 R542 K640 T279 G281 S282 T283 G402 E403 P404 D426 T427 Y428 W429 M430 T431 D517 I529 R532 K630 6.2.1.1 J9VFT1 HHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSGSTGKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f B 2.45 BS03 6R9 B 1 I335 G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 I539 K640 I325 G402 E403 P404 D426 T427 Y428 W429 M430 T431 D517 I529 K630 6.2.1.1 J9VFT1 HHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSGSTGKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f C 2.45 BS01 ATP C 1 T289 S290 G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 I539 R542 K640 T279 S280 G398 E399 P400 D422 T423 Y424 W425 M426 T427 D513 I525 R528 K626 6.2.1.1 J9VFT1 HHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f C 2.45 BS02 6R9 C 1 I335 V411 G412 E413 P414 D436 T437 Y438 W439 M440 T441 D527 I539 R542 I321 V397 G398 E399 P400 D422 T423 Y424 W425 M426 T427 D513 I525 R528 6.2.1.1 J9VFT1 HHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5k8f C 2.45 BS03 MG C 1 E90 H91 E80 H81 6.2.1.1 J9VFT1 HHVHPLPDSVPESEDLFAPPPRMQGKEGRPKPHIGPNYESYVKEWAKTVGPNSDEWWAAKARETLDWYDDFKTVRAGGFEHGDVQWFPEGTLNAAYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAESLRDRVNDCECKVLITTDEGRRGGKTIATKQIVDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSKPKGVVHSTAGYLLGTALTLKYVFDAHPDDRFACMADIGWITGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRMGEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFAGKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVARRPWPSIARTVYRDHKRYLETYMKPYPGYFFFGDGAARDYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTGQAVYAFVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEPQIVEEVKQKVT 5kbe A 2.50 BS01 ZN A 1 C155 E178 C181 C189 C141 E164 C167 C175 Q43965 27362503 EQNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWDAVSDEIIALQAEL 5kbe A 2.50 BS02 IPH A 1 F99 G102 P103 H106 V114 F132 W134 Y161 Y165 S166 Y176 F85 G88 P89 H92 V100 F118 W120 Y147 Y151 S152 Y162 Q43965 27362503 EQNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWDAVSDEIIALQAEL 5kbg A 2.80 BS02 JZ0 A 1 G102 P103 H106 V114 F132 W134 Y161 A162 S166 Y176 G87 P88 H91 V99 F117 W119 Y146 A147 S151 Y161 Q43965 27362503 QNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWEFMSPDAVSDEIIALQAEL 5kbg B 2.80 BS02 JZ0 B 1 G102 P103 H106 V114 F132 W134 Y161 A162 Y165 I191 G88 P89 H92 V100 F118 W120 Y147 A148 Y151 I177 Q43965 27362503 EQNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWENFMSPDAVSDEIIALQ 5kbh A 2.55 BS02 3CH A 1 F99 G102 P103 H106 V114 F132 W134 A162 Y165 S166 Y176 I191 F85 G88 P89 H92 V100 F118 W120 A148 Y151 S152 Y162 I177 Q43965 27362503 EQNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWENDAVSDEIIALQAELN 5kbi A 2.90 BS02 CAQ A 1 F99 G102 P103 H106 V114 F132 W134 Y161 Y165 Y176 I191 F85 G88 P89 H92 V100 F118 W120 Y147 Y151 Y162 I177 Q43965 27362503 EQNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWEPDAVSDEIIALQAELN 5kby A 2.24 BS01 6RL A 1 R125 E205 E206 Y547 S630 Y631 V656 W659 Y662 Y666 V711 R84 E164 E165 Y506 S589 Y590 V615 W618 Y621 Y625 V670 3.4.14.5 P27487 27328054 RKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 5kby D 2.24 BS01 6RL D 1 R125 E205 E206 F357 Y547 S630 Y631 V656 W659 Y662 Y666 N710 V711 R84 E164 E165 F316 Y506 S589 Y590 V615 W618 Y621 Y625 N669 V670 3.4.14.5 P27487 27328054 RKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 5ke2 A 1.56 BS01 6S4 A 1 W358 W363 F379 D382 R384 C385 E386 W165 W170 F186 D189 R191 C192 E193 Q15047 ENLYFQGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFS 5kiv A 1.75 BS01 ZN A 1 C113 H118 C120 C112 H117 C119 3.2.1.- P67344 27345688 GSHMASMETLKSNKARLEYLINDMRRERMPSSFEDLWELYRGLANVRPALPVSDEYLAVQDAMLSDLNHQHVTDLKDLKPIKGDNIFVWQGDITTLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVGKAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVESYLKETNSTLKVVFNVFTDKDLQLYKEALNR 5kkn B 2.60 BS01 6U3 B 1 I270 K274 R277 R281 V587 P590 E593 M594 K678 N679 V680 W681 F704 S705 I30 K34 R37 R41 V336 P339 E342 M343 K411 N412 V413 W414 F426 S427 6.4.1.2,6.3.4.14 O00763 26976583 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFNPPLARGHVIAARITSTVQELNFRSSKNVWGYFSVAQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLI 5kkn C 2.60 BS01 6U3 C 1 I270 K274 R277 R281 V587 P590 E593 M594 V648 N679 W681 F704 S705 I30 K34 R37 R41 V334 P337 E340 M341 V392 N411 W413 F421 S422 6.4.1.2,6.3.4.14 O00763 26976583 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPPLARGHVIAARITSTVQELNFRSSKNVWGYFFGHCFSWGENREEAISNMVVALKELSTVEYLINLLETESFQNNDIDTGWLDYLI 5kl0 A 1.85 BS01 G16 A 1 S119 G324 H325 E342 S344 H346 R436 S438 N439 T440 R445 S97 G302 H303 E320 S322 H324 R414 S416 N417 T418 R423 Q8PGN7 MTLPAFKAYDIRGRVPDELNEDLARRIGVALAAQLDQGPVVLGHDVRLASPALQEALSAGLRASGRDVIDIGLCGTEEVYFQTDYLKAAGGVMVTASHNPMDYNGMKLVREQARPISSDTGLFAIRDTVAADTAAPGEPTASEQSRTDKTAYLEHLLSYVDRSTLKPLKLVVNAGNGGAGLIVDLLAPHLPFEFVRVFHEPDGNFPNGIPNPLLPENRDATAKAVKDNGADFGIAWDGDFDRCFFFDHTGRFIEGYYLVGLLAQAILAKQPGGKVVHDPRLTWNTVEQVEEAGGIPVLCKSGHAFIKEKMRSENAVYGGEMSAHHYFREFAYADSGMIPWLLIAELVSQSGRSLADLVEARMQKFPCSGEINFKVADAKASVARVMEHYASLSPELDYTDGISADFGQWRFNLRSSNTEPLLRLNVETRGDAALLETRTQEISNLLRG 5kob A 1.60 BS01 FE2 A 1 Q51 C99 H141 H145 Q53 C101 H143 H147 3.5.1.88 Q13XB1 HHMIREILKMGDPRLLRIADPVDHFDTPELHELVKDMFETMHDANGAGLAAPQIGVNLQVVIFGFGHNERYPDAPPVPETVLINPTITPVSQDMEEGWEGCLSVPGLRGAVSRFSMIKYHGFDQYGKPIDRVAEGFHARVVQHECDHLIGKLYPMRINDFAKFGFTEVLFP 5koi A 1.70 BS01 NAD A 1 G14 V15 A16 S20 L21 Q41 C64 D65 V66 A92 I93 G94 I120 L145 T146 Y147 K164 A190 G191 P192 V193 T195 L196 A197 G13 V14 A15 S19 L20 Q40 C63 D64 V65 A91 I92 G93 I119 L144 T145 Y146 K163 A189 G190 P191 V192 T194 L195 A196 1.3.1.9 Q57A95 EGLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVLPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYSFTEVAQRAEKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVTGEIHFVDSGYNIVSMPTLEELKSSDSERGE 5koi B 1.70 BS01 NAD B 1 G14 V15 A16 S20 L21 Q41 C64 D65 V66 A92 I93 G94 L145 T146 K164 A190 G191 P192 V193 G13 V14 A15 S19 L20 Q40 C63 D64 V65 A91 I92 G93 L144 T145 K163 A189 G190 P191 V192 1.3.1.9 Q57A95 EGLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVLPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYSFTEVAQRAEKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVRTLAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVTGEIHFVDSGYNIVSMPTLEELKSSDSERGE 5koi C 1.70 BS01 NAD C 1 G14 V15 A16 S20 L21 Q41 L45 C64 D65 V66 A92 I93 G94 F95 I120 L145 T146 Y147 K164 A190 G191 P192 V193 G13 V14 A15 S19 L20 Q40 L44 C63 D64 V65 A91 I92 G93 F94 I119 L144 T145 Y146 K163 A189 G190 P191 V192 1.3.1.9 Q57A95 EGLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVLPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYSFTEVAQRAEKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVRTGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVTGEIHFVDSGYNIVSMPTLEELKSSDSER