3jd8 A 4.43 BS01 CLR A 1 N41 Q79 L83 N86 P90 F108 L111 T112 L176 Y192 M193 N198 A201 P202 F203 I205 N19 Q57 L61 N64 P68 F86 L89 T90 L154 Y170 M171 N176 A179 P180 F181 I183 O15118 QSCVWYGECGIAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFFFGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYI 4yus A 1.80 BS01 FMN A 1 Y6 I22 S26 K29 N30 L39 F46 Q48 L50 I60 R63 I64 D67 R69 M92 Y6 I22 S26 K29 N30 L39 F46 Q48 L50 I60 R63 I64 D67 R69 M92 4.6.1.1 K9TLZ5 MKRLTYISKFSRPLSGDEIEAIGRISSQKNQQANVTGVLLCLDGIFFQILEGEAEKIDRIYERILADERHTDILCLKSEVEVQERMFPDWSMQTINLDENTDFLIRPIKVLLQTLTESHRILEKYTQPSIFKIISQGTNPLNIRPKAVEKIVFFSDIVSFSTFAEKLPVEEVVSVVNSYFSVCTAIITRQGGEVTKFIGDCVMAYFDGDCADQAIQASLDILMELEILRNSAPEGSPLRVLYSGIGLAKGKVIEGNIGSELKRDYTILGDAVNVAARLEALTRQLSQALVFSSEVKNSATKSWNFIWLTDSELKGKSESIDIYSIDNEMTRKSSGGLEIARNIGHYLERV 4yut B 2.90 BS01 FMN B 1 Y6 I22 I25 S26 K29 N30 L39 F46 Q48 R63 D67 R69 H70 M92 Y7 I23 I26 S27 K30 N31 L40 F47 Q49 R64 D68 R70 H71 M93 4.6.1.1 K9TLZ5 HMKRLTYISKFSRPLSGDEIEAIGRISSQKNQQANVTGVLLCLDGIFFQILEGEAEKIDRIYERILADERHTDILCLKSEVEVQERMFPDWSMQTINLDENTDFLIRPIKVLLQTLTESHRILEKYTQPSIFKIISQGTNPLNIRPKAVEKIVFFSDIVSFSTFAEKLPVEEVVSVVNSYFSVCTAIITRQGGEVTKFIGDCVMAYFDGDCADQAIQASLDILMELEILRNSAPEGSPLRVLYSGIGLAKGKVIEGNIGSELKRDYTILGDAVNVAARLEALTRQLSQALVFSSEVKNSATKSWNFIWLTDSELKGKSESIDIYSIDNEMTRKSSGGLEIARNIGHYLERV 4zht A 2.69 BS01 UDP A 1 R19 A20 S23 K24 R113 L218 H220 L250 N253 H281 V282 F284 F287 S301 S302 C303 E307 R321 R13 A14 S17 K18 R107 L212 H214 L244 N247 H275 V276 F278 F281 S295 S296 C297 E301 R315 3.2.1.183 Q9Y223 NRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFP 4zht A 2.69 BS02 NCC A 1 D53 K259 V262 E271 A278 V279 K280 H281 D47 K253 V256 E265 A272 V273 K274 H275 3.2.1.183 Q9Y223 NRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFP 4zht B 2.69 BS02 NCC B 1 D53 F251 K259 V262 R266 E271 A278 V279 K280 H281 D46 F244 K252 V255 R259 E264 A271 V272 K273 H274 3.2.1.183 Q9Y223 RKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF 4zht C 2.69 BS01 UDP C 1 R19 S23 K24 R113 L218 H220 L250 N253 H281 V282 F284 F287 S301 S302 E307 R321 R14 S18 K19 R108 L213 H215 L245 N248 H276 V277 F279 F282 S296 S297 E302 R316 3.2.1.183 Q9Y223 NNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFC 4zht C 2.69 BS02 NCC C 1 D53 F251 K259 V262 E271 A278 V279 K280 H281 D48 F246 K254 V257 E266 A273 V274 K275 H276 3.2.1.183 Q9Y223 NNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFC 4zht C 2.69 BS03 BM7 C 1 R19 Y22 S23 A26 M60 D64 H281 P283 F284 D285 R14 Y17 S18 A21 M55 D59 H276 P278 F279 D280 3.2.1.183 Q9Y223 NNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFC 4zjx A 1.94 BS01 III B 1 V70 D159 I161 Q162 F163 E164 F194 H223 E224 H227 V245 L256 E257 V258 E262 R363 Y366 L367 N368 D370 F423 V70 D159 I161 Q162 F163 E164 F194 H223 E224 H227 V245 L250 E251 V252 E256 R357 Y360 L361 N362 D364 F417 3.4.24.69 P10845 MPFVNKQFNYKDPVNGVDIAYIKIPNVGQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLNPPPEAKQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTELKVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHEVLNLTRNGYGSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAGHRLYGIAINPNRVFKVNMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDIASTLNKAKSIVGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVKFFKVLNRKTYLNFDKAVFKINIVPKVNYTIYDGFNLRNTNLAANFNGQNTEINNMNFTKLKNFTGLF 4zte A 2.13 BS04 4RL A 1 I4 P6 I7 S8 C9 L21 I1 P3 I4 S5 C6 L18 P12830 27120112 IPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTD 4zte A 2.13 BS05 4RL B 1 P5 P6 S8 C9 P10 P2 P3 S5 C6 P7 P12830 27120112 IPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTD 4zte B 2.13 BS01 4RL A 1 P5 P6 I7 S8 P10 E13 P2 P3 I4 S5 P7 E10 P12830 27120112 IPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTD 4zte B 2.13 BS05 4RL B 1 I4 P5 P6 I7 S8 N20 L21 T97 T99 I1 P2 P3 I4 S5 N17 L18 T94 T96 P12830 27120112 IPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTD 4zub A 2.39 BS02 OB1 A 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 F404 V418 M421 I424 G521 H524 L525 M39 L42 T43 A46 E49 L83 M84 L87 R90 F100 V114 M117 I120 G210 H213 L214 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 4zub B 2.39 BS01 III D 1 I358 L372 V376 L379 E380 D538 L539 E542 I50 L64 V68 L71 E72 D216 L217 E220 P03372 NSLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKNVVPLSDLLLEMLDAHRL 4zub B 2.39 BS02 OB1 B 1 M343 L346 T347 A350 E353 L387 M388 R394 F404 V418 G420 M421 I424 G521 H524 L525 M528 L540 M35 L38 T39 A42 E45 L79 M80 R86 F96 V110 G112 M113 I116 G201 H204 L205 M208 L218 P03372 NSLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKNVVPLSDLLLEMLDAHRL 4zuc B 1.82 BS02 OB2 B 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 F404 V418 E419 M421 I424 G521 H524 L525 M528 L540 M39 L42 T43 A46 E49 L83 M84 L87 R90 F100 V114 E115 M117 I120 G204 H207 L208 M211 L223 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 4zw2 A 1.86 BS01 III B 1 M163 M164 K166 A167 K261 I262 V267 R270 L271 S274 R275 E307 N308 L310 A313 M149 M150 K152 A153 K247 I248 V253 R256 L257 S260 R261 E293 N294 L296 A299 Q8R3Z5 REALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSS 4zwh A 1.85 BS01 III D 1 I358 K362 V376 D538 L539 E542 M543 I47 K51 V65 D212 L213 E216 M217 P03372 KNSLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 4zwh A 1.85 BS02 OB3 A 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 F404 V418 G420 M421 I424 G521 H524 L525 M528 L536 M32 L35 T36 A39 E42 L76 M77 L80 R83 F93 V107 G109 M110 I113 G195 H198 L199 M202 L210 P03372 KNSLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 4zwk A 2.07 BS02 OB5 A 1 L346 T347 A350 E353 M388 R394 F404 M421 I424 F425 L428 G521 L525 L540 L44 T45 A48 E51 M86 R92 F102 M119 I122 F123 L126 G208 L212 L227 P03372 KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL 4zwk B 2.07 BS02 OB4 B 1 M343 L346 T347 A350 E353 W383 L387 M388 L391 R394 F404 M421 I424 G521 H524 L525 L536 L540 L544 M39 L42 T43 A46 E49 W79 L83 M84 L87 R90 F100 M111 I114 G207 H210 L211 L215 L219 L223 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSPLSDLLLEMLDAHR 4zzg E 3.00 BS01 III 4 1 G19 R20 E25 L28 E159 G12 R13 E18 L21 E145 3.4.25.1 P32379 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGELMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAAE 4zzg F 3.00 BS01 III 4 1 A28 Q31 G32 S33 R51 Q60 K62 L74 A75 G76 L77 A26 Q29 G30 S31 R49 Q58 K60 L72 A73 G74 L75 3.4.25.1 P40302 RNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 4zzg S 3.00 BS01 III 3 1 G19 R20 E25 L28 E159 Y165 G11 R12 E17 L20 E145 Y151 3.4.25.1 P32379 DRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAAE 5a2m H 1.40 BS03 WX5 H 1 H57 Y60A W60D I174 D189 A190 E192 S195 V213 S214 W215 G216 E217 G219 C220 G226 F227 Y228 H43 Y47 W50 I172 D192 A193 E195 S198 V218 S219 W220 G221 E222 G223 C224 G231 F232 Y233 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 5a2p A 2.50 BS01 III E 1 H210 V211 G212 F213 I214 F215 K216 D253 A254 A257 L260 H98 V99 G100 F101 I102 F103 K104 D141 A142 A145 L148 Q9JI92 GIREVILCKDQDGKIGLRLKSVDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPA 5a9s A 2.06 BS01 CA A 1 K220 A221 E222 A223 I226 K216 A217 E218 A219 I222 1.5.1.48 R4SNK4 TDQNLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADLYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 5a9s A 2.06 BS02 NAP A 1 G12 L13 G14 P15 M16 G17 N35 R36 S37 K40 C68 L69 A70 N95 I121 V123 P125 G11 L12 G13 P14 M15 G16 N34 R35 S36 K39 C67 L68 A69 N91 I117 V119 P121 1.5.1.48 R4SNK4 TDQNLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADLYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 5a9s B 2.06 BS01 CA B 1 K220 A221 Q222 A223 I226 K215 A216 Q217 A218 I221 1.5.1.48 R4SNK4 NLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADDALYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAQAPTIDYPGDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 5a9t A 1.50 BS01 YLG A 1 N241 Y282 N237 Y278 1.5.1.48 R4SNK4 NLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADYDALYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDEGVYPGDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 5b30 A 1.60 BS01 GNP A 1 G12 G13 V14 G15 K16 S17 A18 F28 V29 D30 Y32 A59 G60 N116 K117 D119 L120 S145 A146 G12 G13 V14 G15 K16 S17 A18 F28 V29 D30 Y32 A59 G60 N116 K117 D119 L120 S145 A146 P01112 27180801 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQH 5b56 A 2.30 BS01 III C 1 D280 G281 N283 R315 N319 V321 T322 G323 D325 T328 E354 W357 S360 N361 I362 T363 A364 G365 Q369 E396 W399 N403 S406 G407 D211 G212 N214 R246 N250 V252 T253 G254 D256 T259 E285 W288 S291 N292 I293 T294 A295 G296 Q300 E327 W330 N334 S337 G338 P52293 27181198 NQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSV 5b56 A 2.30 BS02 III E 1 S105 F138 W142 N146 A148 S149 G150 T151 S152 T155 Q181 W184 N188 D192 R227 N228 W231 N235 R238 E266 W273 S36 F69 W73 N77 A79 S80 G81 T82 S83 T86 Q112 W115 N119 D123 R158 N159 W162 N166 R169 E197 W204 P52293 27181198 NQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSV 5b56 B 2.30 BS02 III F 1 S105 W142 N146 S149 Q181 W184 N188 G191 W231 S234 N235 R238 D270 W273 Y277 R315 N350 S35 W72 N76 S79 Q111 W114 N118 G121 W161 S164 N165 R168 D200 W203 Y207 R245 N280 P52293 27181198 QGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFSVEEEE 5bmn A 1.27 BS01 MG A 1 S119 D259 D261 D263 S97 D237 D239 D241 5.4.2.2 Q8PGN7 MTLPAFKAYDIRGRVPDELNEDLARRIGVALAAQLDQGPVVLGHDVRLASPALQEALSAGLRASGRDVIDIGLCGTEEVYFQTDYLKAAGGVMVTASHNPMDYNGMKLVREQARPISSDTGLFAIRDTVAADTAAPGEPTASEQSRTDKTAYLEHLLSYVDRSTLKPLKLVVNAGNGGAGLIVDLLAPHLPFEFVRVFHEPDGNFPNGIPNPLLPENRDATAKAVKDNGADFGIAWDGDFDRCFFFDHTGRFIEGYYLVGLLAQAILAKQPGGKVVHDPRLTWNTVEQVEEAGGIPVLCKSGHAFIKEKMRSENAVYGGEMSAHHYFREFAYADSGMIPWLLIAELVSQSGRSLADLVEARMQKFPCSGEINFKVADAKASVARVMEHYASLSPELDYTDGISADFGQWRFNLRSSNTEPLLRLNVETRGDAALLETRTQEISNLLRG 5bmp A 1.85 BS01 G1P A 1 R302 G324 H325 E342 S344 H346 R436 S438 N439 T440 R445 R281 G303 H304 E321 S323 H325 R415 S417 N418 T419 R424 5.4.2.2 Q8PGN7 HMTLPAFKAYDIRGRVPDELNEDLARRIGVALAAQLDQGPVVLGHDVRLASPALQEALSAGLRASGRDVIDIGLCGTEEVYFQTDYLKAAGGVMVTASHNPMDYNGMKLVREQARPISSDTGLFAIRDTVAADTAAPGEPTASEQSRTDKTAYLEHLLSYVDRSTLKPLKLVVNAGNGGAGLIVDLLAPHLPFEFVRVFHEPDGNFPNGIPNPLLPENRDATAKAVKDNGADFGIAWDGDFDRCFFFDHTGRFIEGYYLVGLLAQAILAKQPGGKVVHDPRLTWNTVEQVEEAGGIPVLCKSGHAFIKEKMRSENAVYGGEMSAHHYFREFAYADSGMIPWLLIAELVSQSGRSLADLVEARMQKFPCSGEINFKVADAKASVARVMEHYASLSPELDYTDGISADFGQWRFNLRSSNTEPLLRLNVETRGDAALLETRTQEISNLLRG 5bmr A 1.85 BS02 MG A 1 D259 D261 D263 D236 D238 D240 Q8PGN7 MTLPAFKAYDIRGRVPDELNEDLARRIGVALAAQLDQGPVVLGHDVRLASPALQEALSAGLRASGRDVIDIGLCGTEEVYFQTDYLKAAGGVMVTAHNPMDYNGMKLVREQARPISSDTGLFAIRDTVAADTAAPGEPTASEQSRTDKTAYLEHLLSYVDRSTLKPLKLVVNAGNGGAGLIVDLLAPHLPFEFVRVFHEPDGNFPNGIPNPLLPENRDATAKAVKDNGADFGIAWDGDFDRCFFFDHTGRFIEGYYLVGLLAQAILAKQPGGKVVHDPRLTWNTVEQVEEAGGIPVLCKSGHAFIKEKMRSENAVYGGEMSAHHYFREFAYADSGMIPWLLIAELVSQSGRSLADLVEARMQKFPCSGEINFKVADAKASVARVMEHYASLSPELDYTDGISADFGQWRFNLRSSNTEPLLRLNVETRGDAALLETRTQEISNLLRG 5bnu A 1.60 BS02 OB7 A 1 M343 L346 T347 A350 E353 L387 M388 R394 F404 E419 G420 M421 I424 F425 L428 G521 H524 L525 L540 M41 L44 T45 A48 E51 L85 M86 R92 F102 E117 G118 M119 I122 F123 L126 G209 H212 L213 L228 P03372 KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5bnu B 1.60 BS02 OB6 B 1 L346 T347 A350 E353 W383 L387 M388 L391 R394 F404 M421 I424 G521 L525 L536 L540 L544 L41 T42 A45 E48 W78 L82 M83 L86 R89 F99 M112 I115 G206 L210 L214 L218 L222 P03372 LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYVPLSDLLLEMLDAHR 5bo2 A 2.00 BS01 7P1 A 1 N138 A179 P180 H183 Y186 R187 A190 R193 R194 G206 N108 A143 P144 H147 Y150 R151 A154 R157 R158 G170 2.4.2.18 A5U4M0 SWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGTVNLSTMAAIVVAAAGVPVVKHGNRAGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5bo2 B 2.00 BS01 7P1 B 1 M86 N138 A179 P180 H183 Y186 R187 A190 R193 G206 M62 N110 A149 P150 H153 Y156 R157 A160 R163 G176 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGTVNLSTMAAIVVAAAGVPVVKHGNRAASSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQ 5bo3 B 1.75 BS01 7P2 B 1 M86 N138 A179 P180 H183 P184 Y186 R187 A190 R193 R194 M62 N108 A142 P143 H146 P147 Y149 R150 A153 R156 R157 2.4.2.18 A5U4M0 PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGVNLSTMAAIVVAAAGVPVVKHGNRAADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 5bp6 A 2.03 BS01 III C 1 I358 K362 L372 V376 L379 E380 L539 E542 I49 K53 L63 V67 L70 E71 L217 E220 P03372 LALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNLSDLLLEMLDAHR 5bp6 B 2.03 BS01 III D 1 I358 K362 L372 V376 L379 L539 E542 M543 I54 K58 L68 V72 L75 L221 E224 M225 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSPLSDLLLEMLD 5bp6 B 2.03 BS02 OB8 B 1 L346 T347 A350 E353 L387 M388 R394 F404 V418 E419 M421 I424 G521 H524 L525 L540 L42 T43 A46 E49 L83 M84 R90 F100 V114 E115 M117 I120 G210 H213 L214 L222 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSPLSDLLLEMLD 5bpr A 1.91 BS02 OB9 A 1 M343 L346 T347 A350 E353 L387 M388 R394 E419 M421 I424 G521 H524 L525 M38 L41 T42 A45 E48 L82 M83 R89 E114 M116 I119 G206 H209 L210 P03372 NSLALSLTADQMVSALLDAEPPILYSEYTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5bpr B 1.91 BS02 OB9 B 1 M343 L346 T347 A350 E353 L387 M388 L391 R394 F404 M421 G521 H524 L525 L540 M39 L42 T43 A46 E49 L83 M84 L87 R90 F100 M115 G206 H209 L210 L217 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYPLSDLLLEMLDAHR 5bq4 A 1.78 BS02 OBT A 1 M343 L346 T347 A350 E353 L387 M388 R394 F404 M421 I424 G521 H524 L525 L540 M39 L42 T43 A46 E49 L83 M84 R90 F100 M117 I120 G208 H211 L212 L227 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR 5bq4 B 1.78 BS01 III D 1 I358 K362 L372 Q375 V376 D538 E542 M543 I54 K58 L68 Q71 V72 D220 E224 M225 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVVPLSDLLLEMLDAH 5bq4 B 1.78 BS02 OBT B 1 M343 L346 T347 A350 E353 W383 L387 M388 R394 F404 M421 I424 G521 L525 L540 L544 M39 L42 T43 A46 E49 W79 L83 M84 R90 F100 M117 I120 G208 L212 L222 L226 P03372 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSVVPLSDLLLEMLDAH 5br7 A 1.95 BS01 FAD A 1 V9 G10 G12 L13 F14 V33 E34 K35 R36 G41 N42 Y58 G59 A60 H61 L62 T219 D220 W221 F222 G241 Y325 Y326 G357 R358 Y364 L365 D366 M367 A370 V8 G9 G11 L12 F13 V32 E33 K34 R35 G40 N41 Y57 G58 A59 H60 L61 T218 D219 W220 F221 G240 Y324 Y325 G356 R357 Y363 L364 D365 M366 A369 5.4.99.9 Q6NER4 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 5br7 A 1.95 BS02 FLC A 1 A60 L62 Y187 R288 H290 A59 L61 Y186 R287 H289 5.4.99.9 Q6NER4 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 5c1u A 1.49 BS01 GHV A 1 R39 H40 E71 L127 S128 T142 K143 A144 C147 H161 I162 G163 G164 R40 H41 E72 L128 S129 T143 K144 A145 C148 H162 I163 G164 G165 3.4.22.28 A9XG43 27185390 MGPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNILDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKVIGIHIGGNGRQGFCAGLKRSYFA 5c1x A 1.86 BS01 GHX A 1 R39 H40 E71 L125 L127 S128 K130 T142 K143 C147 H161 I162 G163 G164 F170 R40 H41 E72 L126 L128 S129 K131 T143 K144 C148 H162 I163 G164 G165 F171 3.4.22.28 A9XG43 27185390 MGPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNILDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKVIGIHIGGNGRQGFCAGLKRSYFA 5c1x B 1.86 BS01 GHX B 1 R39 H40 E71 L125 N126 L127 S128 T142 K143 A144 C147 H161 I162 G163 G164 F170 R40 H41 E72 L126 N127 L128 S129 T143 K144 A145 C148 H162 I163 G164 G165 F171 3.4.22.28 A9XG43 27185390 MGPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNILDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKVIGIHIGGNGRQGFCAGLKRSYFA 5c66 B 2.03 BS04 WO4 B 1 D51 D101 S102 D153 R166 D327 H331 H370 H412 D43 D93 S94 D145 R158 D319 H323 H362 H404 3.1.3.1 P00634 27189921 NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK 5cp6 D 2.60 BS01 NUC I 1 T29 S52 S53 R83 S84 T85 T2 S25 S26 R56 S57 T58 P02281 27184539 KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 5cp6 E 2.60 BS02 NUC J 1 H39 R40 Y41 R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 H2 R3 Y4 R5 T8 R26 R35 R46 F47 Q48 S49 R79 V80 T81 M83 P84233 27184539 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE 5czv A 3.19 BS02 CA A 2 L1436 N1439 R1441 D1443 D1454 L46 N49 R51 D53 D64 Q9UM47 27157619 ACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYHIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEP 5dlx A 1.90 BS01 5D2 A 1 F79 W81 P82 F83 V87 L92 L94 N140 D145 I146 L148 M149 F38 W40 P41 F42 V46 L51 L53 N99 D104 I105 L107 M108 O60885 27219844 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPT 5dlz A 1.70 BS01 5D1 A 1 P82 F83 V87 V90 K91 L92 N93 L94 N140 I146 P41 F42 V46 V49 K50 L51 N52 L53 N99 I105 O60885 27219844 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 5dva A 2.50 BS01 5FL A 1 S70 W105 S118 T209 Y211 R250 S47 W82 S95 T186 Y188 R227 3.5.2.6 Q6XEC0 27165692 EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 5dva B 2.50 BS01 5FL B 1 S70 S118 V120 T209 Y211 R250 S47 S95 V97 T186 Y188 R227 3.5.2.6 Q6XEC0 27165692 EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 5dva C 2.50 BS01 5FL C 1 S70 V120 L158 T209 Y211 R250 S47 V97 L135 T186 Y188 R227 3.5.2.6 Q6XEC0 27165692 EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 5dva D 2.50 BS01 5FL D 1 S70 I102 W105 S118 T209 Y211 S244 L247 R250 S47 I79 W82 S95 T186 Y188 S221 L224 R227 3.5.2.6 Q6XEC0 27165692 EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP 5e40 A 2.05 BS03 DTY B 1 D10 V55 Y173 A174 D10 V55 Y173 A174 2.5.1.54 27128682 MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5e40 B 2.05 BS01 DTY A 1 W3 V55 Y173 A174 W3 V49 Y167 A168 2.5.1.54 27128682 MNWTVDIPIPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5e4n A 2.05 BS03 DTY B 1 L12 V55 Y173 A174 L12 V55 Y173 A174 2.5.1.54 27128682 MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5e7z A 2.40 BS02 DTR A 1 L107 A110 K123 A192 L194 N237 L238 T240 L104 A107 K120 A189 L191 N234 L235 T237 2.5.1.54 27128682 MNWTVDIPIDQLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5e7z A 2.40 BS04 DPN A 1 F91 R171 N175 F88 R168 N172 2.5.1.54 27128682 MNWTVDIPIDQLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5e7z B 2.40 BS03 DTR B 1 L107 A110 V111 K123 A192 L194 N237 L238 T240 L101 A104 V105 K117 A186 L188 N231 L232 T234 2.5.1.54 27128682 MNWTVDIPIPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5e7z B 2.40 BS04 TRP B 1 L107 A110 K123 A192 L194 N237 L238 T240 A241 L101 A104 K117 A186 L188 N231 L232 T234 A235 2.5.1.54 27128682 MNWTVDIPIPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5ej4 A 1.77 BS01 TD6 A 1 N390 S391 L392 R395 R413 S416 G417 I418 D419 G441 D442 L443 S444 Y447 N469 G471 G472 Q473 I474 F475 N390 S391 L392 R395 R413 S416 G417 I418 D419 G441 D442 L443 S444 Y447 N469 G471 G472 Q473 I474 F475 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5ej4 A 1.77 BS03 TD6 B 1 P30 E55 T78 T81 A82 N85 N117 Q118 P30 E55 T78 T81 A82 N85 N117 Q118 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5ej4 C 1.77 BS03 TD6 D 1 P30 E55 T81 A82 N85 N117 Q118 P30 E55 T81 A82 N85 N117 Q118 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5ej5 D 2.30 BS01 TD6 C 1 P30 E55 T81 A82 N117 Q118 P30 E55 T81 A82 N117 Q118 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5ej7 A 1.56 BS03 TD6 B 1 P30 E55 T78 T81 A82 N117 Q118 P30 E55 T78 T81 A82 N117 Q118 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5ej8 A 1.34 BS04 MG A 2 K70 D311 K70 D311 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5ej9 A 1.72 BS01 TPP A 1 S391 L392 S416 G417 I418 D419 G441 D442 L443 S444 Y447 N469 G471 G472 Q473 I474 F475 S391 L392 S416 G417 I418 D419 G441 D442 L443 S444 Y447 N469 G471 G472 Q473 I474 F475 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5eja C 1.60 BS03 TD6 D 1 P30 G31 E55 T81 A82 N85 N117 Q118 P30 G31 E55 T81 A82 N85 N117 Q118 2.2.1.9 P17109 27213829 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL 5eom A 2.55 BS01 TMO A 1 P188 L189 P190 I192 P195 P187 L188 P189 I191 P194 Q13394 DIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5eom A 2.55 BS02 CTP A 1 R23 K24 I27 I31 R62 Y63 L66 V68 K248 S252 K255 R23 K24 I27 I31 R61 Y62 L65 V67 K238 S242 K245 Q13394 DIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5eom F 2.55 BS01 TMO F 1 S144 Y145 S137 Y138 Q13394 GAMDIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQVFNFVDGSLPGCAVLKLSSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPIPWPGPNRVAEVKAEGFNLLSKESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5eom I 2.55 BS01 CTP I 1 R23 K24 A28 I31 R62 Y63 K248 S252 R23 K24 A28 I31 R59 Y60 K235 S239 Q13394 DIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNERYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5eom J 2.55 BS01 CTP J 1 R23 K24 I27 A28 I31 R32 Y63 L66 V68 K248 S252 K255 R25 K26 I29 A30 I33 R34 Y53 L56 V58 K175 S179 K182 Q13394 AMDIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPYEGLEVISPTEFEVVLYLLPGCAVFITAYLSARKIRSRFQTLVAQAVDKCSYRDVKLRIRDRYVVQITPAKCTGWPRSAAHWPLPHIGPNRVAEVKAEGFNLLSWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5eom C 2.55 BS01 TMO C 1 T72 R161 R165 V167 T75 R164 R168 V170 Q13394 GAMDIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5eom C 2.55 BS02 TMO C 2 P188 L189 P190 I192 P191 L192 P193 I195 Q13394 GAMDIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL 5esr A 1.48 BS01 CO A 1 D238 H303 H305 D238 H303 H305 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5esr A 1.48 BS02 CO A 2 H304 H306 H304 H306 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5esr A 1.48 BS03 MG A 1 N180 T183 R185 N180 T183 R185 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5esr A 1.48 BS04 CO A 3 E256 T273 E256 T273 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5esr A 1.48 BS05 CO A 4 D123 W124 D123 W124 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5esr A 1.48 BS06 CO A 5 H22 D40 E41 H22 D40 E41 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5esr A 1.48 BS07 MG A 2 H74 D293 H74 D293 3.8.1.5 Q9A919 26833751 MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQAHHHHHH 5ev8 A 2.30 BS02 ZN A 2 C158 H197 C156 H195 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5ev8 A 2.30 BS03 3R9 A 1 V31 H77 H79 D81 H139 C158 K161 N167 H197 V29 H75 H77 D79 H137 C156 K159 N165 H195 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5ev8 A 2.30 BS04 3R9 A 2 G110 K111 V112 G108 K109 V110 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5ev8 B 2.30 BS03 3R9 B 1 V31 H77 H79 D81 H139 C158 K161 L165 G166 N167 H197 V29 H75 H77 D79 H137 C156 K159 L163 G164 N165 H195 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5ev8 D 2.30 BS03 3R9 D 1 V31 H79 D81 H139 C158 K161 G166 N167 H197 V28 H76 D78 H136 C155 K158 G163 N164 H194 3.5.2.6 P52699 LPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5evb A 1.84 BS03 3R9 A 1 Y33 H116 H118 D120 H121 F156 I162 H196 P227 H263 Y10 H83 H85 D87 H88 F123 I127 H159 P188 H224 3.5.2.6 P52700 EVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAG 5evd A 1.80 BS01 VC2 A 1 H116 H118 D120 H121 F156 I162 H196 P227 H263 H84 H86 D88 H89 F124 I128 H160 P189 H225 3.5.2.6 P52700 AEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAG 5evk A 1.63 BS01 3C7 A 1 Y33 W39 H116 D120 H121 H196 S225 H263 Y10 W16 H83 D87 H88 H159 S186 H224 3.5.2.6 P52700 EVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAG 5ew0 A 1.30 BS02 3C7 A 1 W80 H109 T110 D111 F146 T147 H186 C205 N213 F216 H247 W40 H69 T70 D71 F106 T107 H146 C165 N173 F176 H207 3.5.2.6 Q9RMI1 NLTLTHFKGPLYIVEDKEYVQENSMVYIGTDGITIIGATWTPETAETLYKEIRKVSPLPINEVINTNYHTDRAGGNAYWKTLGAKIVATQMTYDLQKSQWGSIVNFTRQGNNKYPNLEKSLPDTVFPGDFNLQNGSIRAMYLGEAHTKDGIFVYFPAERVLYGNCILKENLGNMSFANRTEYPKTLEKLKGLIEQGELKVDSIIAGHDTPIHDVGLIDHYLTLLEKAP 5ewa A 2.30 BS03 9BZ A 1 W28 V31 H79 D81 H139 C158 K161 G166 N167 H197 W26 V29 H77 D79 H137 C156 K159 G164 N165 H195 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5ewa B 2.30 BS03 9BZ B 1 V25 W28 H79 D81 H139 C158 K161 G166 N167 H197 V23 W26 H77 D79 H137 C156 K159 G164 N165 H195 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5ewa C 2.30 BS03 9BZ C 1 W28 H77 H79 D81 H139 C158 K161 G166 N167 H197 W26 H75 H77 D79 H137 C156 K159 G164 N165 H195 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPS 5ewa D 2.30 BS03 9BZ D 1 K181 V214 K179 V212 3.5.2.6 P52699 SLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESK 5f09 A 1.85 BS04 BC8 A 1 R210 N257 A424 E425 G427 G518 N519 R534 Y552 H553 K699 Y700 R156 N203 A370 E371 G373 G464 N465 R480 Y498 H499 K645 Y646 3.4.17.21 Q04609 27208881 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAAEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA 5fh6 A 2.30 BS01 5XM A 1 I683 F684 L687 Y696 M704 D705 M731 A735 N739 I745 I31 F32 L35 Y44 M52 D53 M79 A83 N87 I93 Q86U86 27119626 KYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDL 5fh6 C 2.30 BS01 5XM C 1 I683 F684 L687 Y696 A735 Y738 N739 I29 F30 L33 Y42 A81 Y84 N85 Q86U86 27119626 MTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDL 5fh6 D 2.30 BS01 5XM D 1 I683 F684 R686 L687 P688 Y696 M704 A735 N739 I745 I27 F28 R30 L31 P32 Y40 M48 A79 N83 I89 Q86U86 27119626 PMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDL 5fh7 A 1.47 BS01 5XL A 1 I683 F684 L687 P688 L693 Y696 M704 M731 A735 Y738 N739 I745 I32 F33 L36 P37 L42 Y45 M53 M80 A84 Y87 N88 I94 Q86U86 27119626 SKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGD 5fh8 B 1.55 BS01 5XK B 1 I683 F684 R686 L687 L693 Y696 M704 D705 M731 A735 N739 I745 I31 F32 R34 L35 L41 Y44 M52 D53 M79 A83 N87 I93 Q86U86 27119626 KYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDL 5flh A 1.80 BS01 NI A 1 H69 H71 E76 H115 H67 H69 E74 H113 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTGSIEGRKL 5fli A 2.15 BS02 QUE A 1 L35 F56 C58 H69 H71 E76 V77 F78 Y117 G128 F137 F140 F141 F176 L33 F54 C56 H67 H69 E74 V75 F76 Y115 G126 F135 F138 F139 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fli B 2.15 BS02 QUE B 1 L35 F56 C58 I66 H69 H71 E76 V77 F78 V126 G128 F140 F141 L33 F54 C56 I64 H67 H69 E74 V75 F76 V124 G126 F138 F139 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fli C 2.15 BS02 QUE C 1 L35 C58 H69 H71 E76 V77 F78 Y117 V126 G128 F140 F141 F176 L33 C56 H67 H69 E74 V75 F76 Y115 V124 G126 F138 F139 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fli D 2.15 BS02 QUE D 1 L35 F36 F56 C58 I66 H69 H71 E76 V77 Y117 V126 G128 F137 F140 F141 F176 L33 F34 F54 C56 I64 H67 H69 E74 V75 Y115 V124 G126 F135 F138 F139 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fli G 2.15 BS02 QUE G 1 L35 C58 I66 H69 H71 E76 V77 F78 Y117 V126 G128 F137 F140 F141 F176 L33 C56 I64 H67 H69 E74 V75 F76 Y115 V124 G126 F135 F138 F139 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fli H 2.15 BS02 QUE H 1 L35 F36 F56 C58 H69 H71 E76 V77 F78 Y117 V126 G128 F137 F140 F141 V174 F176 L33 F34 F54 C56 H67 H69 E74 V75 F76 Y115 V124 G126 F135 F138 F139 V172 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fli J 2.15 BS02 QUE J 1 L35 F36 C58 I66 H69 H71 E76 V77 F78 Y117 V126 G128 F137 F140 F141 F176 L33 F34 C56 I64 H67 H69 E74 V75 F76 Y115 V124 G126 F135 F138 F139 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5flj A 1.82 BS02 QUE A 1 L35 F36 F56 I66 H69 H71 E76 V77 F78 Y117 V126 G128 F140 F141 F176 L33 F34 F54 I64 H67 H69 E74 V75 F76 Y115 V124 G126 F138 F139 F174 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHT 5flj C 1.82 BS03 OXY C 1 H69 E76 F78 H115 H67 E74 F76 H113 1.13.11.24 A2VA43 26846734 IEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5flj L 1.82 BS02 QUE L 1 L35 F56 I66 H69 H71 E76 V77 F78 Y117 V126 G128 F140 F141 F176 L34 F55 I65 H68 H70 E75 V76 F77 Y116 V125 G127 F139 F140 F175 1.13.11.24 A2VA43 26846734 TIEYATRHRARSFIPPEPGKPYFIEKGLGDRAHLFGDLITIYAGGEQTENTFNFFTCEGPKGEVIPAHSHADTYEVFYITQGAVRLFVEDLEGEQHEKLLTPGDFGFVPKNCVHAYRMERHHSQVVGVAAGPGGTFERFFESLGTPAEELGLPVRPFVPEPEKFRTVPEQYDVRFRPDHQWHTG 5fmi A 1.49 BS02 ZN A 2 E46 E50 E24 E28 Q16611 27198225 SEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRLLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLG 5fmj A 2.43 BS01 III B 1 A93 F97 R100 Y101 F105 L108 L112 S122 Q125 V126 E129 L130 D133 N136 W137 G138 R139 A142 L194 Y195 A200 S203 A38 F42 R45 Y46 F50 L53 L57 S67 Q70 V71 E74 L75 D78 N81 W82 G83 R84 A87 L139 Y140 A145 S148 Q07817 27198225 SMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQE 5fmk A 1.73 BS01 III B 1 E96 F97 R100 Y101 A104 F105 L108 Q111 L112 H113 S122 Q125 V126 E129 L130 N136 W137 G138 R139 A142 F146 T190 E193 L194 Y195 A200 S203 E39 F40 R43 Y44 A47 F48 L51 Q54 L55 H56 S65 Q68 V69 E72 L73 N79 W80 G81 R82 A85 F89 T133 E136 L137 Y138 A143 S146 Q07817 27198225 SQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQ 5fus A 1.87 BS01 DAO A 1 F44 V49 G83 F88 Y103 C107 G110 V111 G135 M167 W255 F36 V41 G75 F80 Y95 C99 G102 V103 G127 M159 W247 4.2.1.17 B4EKM5 27198181 CRPFYEAGELSQLTAFYEEGRNVMWMMLRSEPRPCFNQQLVTDIIHLARVARDSGLTFDFWVTGSLVPELFNVGGDLSFFVDAIRSGRRDQLMAYARSCIDGVYEIYTGFGTGAISIAMVEGSALGGGFEAALAHHYVLAQKGVKLGFPEIAFNLFPGMGGYSLVARKANRGLAESLIATGEAHAAEWYEDCGLIDETFDAGDAYLATRTFIDVTKPKLNGIRAMLRARERVFQLSRSELMDITEAWVHAAFTIEPKDLAYMERLVMLQ 5fvj A 1.70 BS01 ACO A 1 S21 E23 L26 L92 A93 V94 H99 G100 K101 G102 L103 G104 A105 V129 H130 L132 E135 N138 F139 F140 H142 H143 S26 E28 L31 L97 A98 V99 H104 G105 K106 G107 L108 G109 A110 V134 H135 L137 E140 N143 F144 F145 H147 H148 E8XFW6 GPGGTMGRVTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAARTFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNMPDPIPVIILARLAVDLSFHGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFFIHHGFKSSQTQQRTLFLRLP 5fvj B 1.70 BS01 ACO B 1 S21 E23 L26 L92 A93 V94 H99 G100 K101 G102 L103 G104 A105 A131 L132 E135 A136 N138 F139 F140 H142 H143 S18 E20 L23 L89 A90 V91 H96 G97 K98 G99 L100 G101 A102 A128 L129 E132 A133 N135 F136 F137 H139 H140 E8XFW6 VTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAARTFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNMPDPIPVIILARLAVDLSFHGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFFIHHGFKSSQTQQRTLFLRLPQ 5fwn A 2.14 BS01 NAP A 1 L13 G14 P15 M16 N35 R36 S37 K40 L69 A70 A74 S77 L11 G12 P13 M14 N33 R34 S35 K38 L67 A68 A72 S75 1.5.1.48 R4SNK4 DQNLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADYDALYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDYPGDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGSSYYSVIELWR 5fwn A 2.14 BS02 YLG B 1 I121 M122 L175 M178 I119 M120 L173 M176 1.5.1.48 R4SNK4 DQNLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADYDALYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDYPGDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGSSYYSVIELWR 5fwn B 2.14 BS01 YLG B 1 I218 A235 M240 N241 T244 I214 A227 M232 N233 T236 1.5.1.48 R4SNK4 NLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLADYDALYSALGPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIYPGDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 5g32 A 2.20 BS01 NUC C 1 T228 K229 T230 E231 E234 D240 N256 H258 A263 R264 M265 Q266 T41 K42 T43 E44 E47 D53 N69 H71 A76 R77 M78 Q79 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHR 5g32 A 2.20 BS02 NUC D 1 T239 P241 F262 R294 R301 T52 P54 F75 R107 R114 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHR 5g33 B 2.40 BS04 NUC F 1 T239 P241 F262 R294 K298 T52 P54 F75 R107 K111 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRR 5g34 B 1.90 BS04 NUC F 1 T239 P241 F262 T52 P54 F75 P28519 APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHR 5hgg S 1.97 BS01 TWN S 1 R45 Y95 W117 R45 Y95 W117 QVQLQESGGGLVQAGGSLRLSCAASGFTLDSYAIGWFRQAPGKEREGVSCISASGGSTNYADSVKGRFTISRDNAKNTVYLQMNSLKSEDTAVYYCAADHPGLCTSESGRRRYLEVWGQGTQVTVSSA 5hgg S 1.97 BS02 TWN S 2 F37 R45 G47 V48 Y60 H100 L103 E115 W117 F37 R45 G47 V48 Y60 H100 L103 E115 W117 QVQLQESGGGLVQAGGSLRLSCAASGFTLDSYAIGWFRQAPGKEREGVSCISASGGSTNYADSVKGRFTISRDNAKNTVYLQMNSLKSEDTAVYYCAADHPGLCTSESGRRRYLEVWGQGTQVTVSSA 5hgg T 1.97 BS01 TWN S 1 Q39 R45 Y95 W117 Q39 R45 Y95 W117 QVQLQESGGGLVQAGGSLRLSCAASGFTLDSYAIGWFRQAPGKEREGVSCISASGGSTNYADSVKGRFTISRDNAKNTVYLQMNSLKSEDTAVYYCAADHPGLCTSESGRRRYLEVWGQGTQVTVSS 5hgg T 1.97 BS02 TWN T 1 F37 R45 V48 C50 N59 Y60 A61 L103 E115 W117 F37 R45 V48 C50 N59 Y60 A61 L103 E115 W117 QVQLQESGGGLVQAGGSLRLSCAASGFTLDSYAIGWFRQAPGKEREGVSCISASGGSTNYADSVKGRFTISRDNAKNTVYLQMNSLKSEDTAVYYCAADHPGLCTSESGRRRYLEVWGQGTQVTVSS 5hhv A 2.20 BS01 III I 1 N108 S109 F110 R111 L112 K114 N69 S70 F71 R72 L73 K75 Q16552 27184415 SSDYYDRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHSPNSFRLEKILVSVGCTCVTPIVH 5hnk A 2.22 BS01 NUC X 1 F32 H36 R86 T152 K153 G154 T170 F13 H17 R67 T133 K134 G135 T151 3.1.11.3 P06229 RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTKGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ 5hnk A 2.22 BS02 NUC Y 1 L202 E210 G211 I212 G213 A214 K215 R216 L183 E191 G192 I193 G194 A195 K196 R197 3.1.11.3 P06229 RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTKGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ 5hnk B 2.22 BS01 NUC X 1 F32 R33 K35 E210 G211 G213 A214 K215 R216 F13 R14 K16 E191 G192 G194 A195 K196 R197 3.1.11.3 P06229 RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTKGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ 5hnk B 2.22 BS02 NUC Y 1 F32 D68 K69 G70 K71 L76 R86 Y90 F105 T152 K153 G154 T171 F13 D49 K50 G51 K52 L57 R67 Y71 F86 T133 K134 G135 T152 3.1.11.3 P06229 RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTKGDWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ 5hoo A 3.30 BS01 NUC C 1 R12 P41 T42 K44 T45 R48 W49 R52 D62 K63 E64 H65 G66 K67 P68 P69 T88 Q89 Q100 Q101 S104 R108 Q114 R10 P39 T40 K42 T43 R46 W47 R50 D60 K61 E62 H63 G64 K65 P66 P67 T86 Q87 Q98 Q99 S102 R106 Q112 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hoo A 3.30 BS02 NUC D 1 K8 T24 A25 A26 R30 K44 E47 Q51 H65 G66 K67 P68 K70 R71 V98 S99 Q101 A102 R106 R167 P174 G175 R183 N185 R186 F187 T213 V214 N215 A216 P252 A256 R257 K6 T22 A23 A24 R28 K42 E45 Q49 H63 G64 K65 P66 K68 R69 V96 S97 Q99 A100 R104 R165 P172 G173 R181 N183 R184 F185 T211 V212 N213 A214 P242 A246 R247 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hoo A 3.30 BS03 NUC E 1 Y171 R324 Y169 R314 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hoo A 3.30 BS04 NUC F 1 K115 V116 R118 P121 K158 W159 K166 R186 F187 K190 T213 V214 P278 D284 F288 A289 G292 H293 K113 V114 R116 P119 K156 W157 K164 R184 F185 K188 T211 V212 P268 D274 F278 A279 G282 H283 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hoo A 3.30 BS05 NUC G 1 D249 N250 P252 A275 Y276 D239 N240 P242 A265 Y266 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hoo B 3.30 BS01 NUC C 1 Y171 Y285 S290 H293 F321 K328 Y169 Y276 S281 H284 F312 K319 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRPRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hoo B 3.30 BS02 NUC D 1 K115 V116 R118 P121 H122 K158 W159 F187 K190 T213 V214 Y276 P278 D284 F288 A289 G292 H293 K113 V114 R116 P119 H120 K156 W157 F185 K188 T211 V212 Y267 P269 D275 F279 A280 G283 H284 3.1.-.- Q7JQ07 SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRPRVIFLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE 5hp1 A 2.90 BS01 NUC F 1 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 G152 K154 P157 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 R358 G359 A360 H361 R448 T473 Q475 K476 Q500 Y501 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 G152 K154 P157 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 R358 G359 A360 H361 R448 T473 Q475 K476 Q500 Y501 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5hp1 A 2.90 BS03 PPF A 1 K65 R72 D110 V111 G112 D113 A114 K65 R72 D110 V111 G112 D113 A114 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5hp1 A 2.90 BS07 ATM F 1 R72 D110 D113 A114 Y115 Q151 D185 R72 D110 D113 A114 Y115 Q151 D185 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5hp1 C 2.90 BS01 NUC E 1 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 G152 K154 P157 Q161 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 N265 W266 V276 S280 R284 G285 T286 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Q500 Y501 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 G152 K154 P157 Q161 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 N265 W266 V276 S280 R284 G285 T286 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Q500 Y501 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5hp1 C 2.90 BS02 PPF C 1 K65 R72 D110 V111 D113 K220 K65 R72 D110 V111 D113 K220 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5hp1 C 2.90 BS07 ATM E 1 D110 D113 A114 Y115 D185 D110 D113 A114 Y115 D185 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5hp4 A 1.86 BS01 NUC X 1 F32 R33 K35 H36 N37 N38 S39 L54 T94 E96 E97 L100 F167 F169 R172 E210 G211 G213 A214 K215 R216 F13 R14 K16 H17 N18 N19 S20 L35 T75 E77 E78 L81 F148 F150 R153 E191 G192 G194 A195 K196 R197 3.1.11.3 P06229 RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTDGKWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ 5hp4 A 1.86 BS02 CA A 1 E128 D130 D153 E109 D111 D134 3.1.11.3 P06229 RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDKGKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTFPTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTDGKWDTLLTDKVSRFSFTTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYNIIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDAIAAVGQDVLDKFTKDILEIAEQ 5hro A 2.75 BS01 NUC E 1 W24 L74 R78 N81 E89 Q91 I94 G152 W153 K154 P157 Q161 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 G285 K353 A355 R358 G359 A360 H361 K374 R448 T473 Q475 K476 Q500 Y501 W21 L71 R75 N78 E86 Q88 I91 G149 W150 K151 P154 Q158 Y180 M181 D182 D183 M227 G228 N252 Q255 K256 G259 K260 W263 S277 R281 G282 K350 A352 R355 G356 A357 H358 K371 R445 T470 Q472 K473 Q497 Y498 2.7.7.49 P03366 27192549 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 5hro A 2.75 BS04 3JY A 1 R72 D110 A114 Y115 M184 D185 R69 D107 A111 Y112 M181 D182 2.7.7.49 P03366 27192549 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 5hro C 2.75 BS05 3JY C 1 R72 D110 D113 A114 Y115 M184 D185 R69 D107 D110 A111 Y112 M181 D182 2.7.7.49 P03366 27192549 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 5hs1 A 2.10 BS01 HEM A 1 F113 Y126 Y140 L147 K151 V311 G315 T318 L374 H378 P379 L383 R385 P462 F463 G464 H468 C470 I471 G472 A476 F107 Y120 Y134 L141 K145 V305 G309 T312 L368 H372 P373 L377 R379 P456 F457 G458 H462 C464 I465 G466 A470 A6ZSR0 27188873 IVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNPEQKIGGRH 5hs1 A 2.10 BS02 VOR A 1 Y126 F134 I139 F236 G310 G314 T318 L380 S382 L383 Y120 F128 I133 F230 G304 G308 T312 L374 S376 L377 A6ZSR0 27188873 IVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNPEQKIGGRH 5hzq A 1.75 BS01 YWZ A 1 F15 A32 P39 T54 V76 L121 R132 Y134 F17 A34 P41 T56 V78 L123 R134 Y136 P29373 27191344 HMPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE 5hzq B 1.75 BS01 YWZ B 1 F15 A32 P39 V41 T54 V76 L121 R132 Y134 F14 A31 P38 V40 T53 V75 L120 R131 Y133 P29373 27191344 NFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE 5i2g A 2.35 BS01 PGO A 1 H166 H283 S284 F338 F344 G437 C438 E440 D452 V696 H164 H281 S282 F336 F342 G435 C436 E438 D450 V653 Q1A666 NYDSTPIAKSDRIKRLVDHLYAKMPEIEAARAELITESFKATEGQPVVMRKARAFEHILKNLPIIIRPEELIVGSTTIAPRGCQTYPEFSYEWLEAEFETVETRSADPFYISEETKKRLLAADAYWKGKTTSELATSYMAPETLRAMKHNFFTPGNYFYNGVGHVTVQYETVLAIGLNGVKEKVRKEMENCHFGDADYSTKMCFLESILISCDAVITYANRYAKMAEEMAEKETDAARRQELLTIARVCKNVPEFPAESFQEACQSFWFIQQVLQIESSGHSISPGRFDQYMYPYYEKDLKEGSLTREYAQELIDCIWVKLNDLNKCRDAASAEGFAGYSLFQNLIVGGQTVQGRDATNDLSFMCITASEHVFLPMPSLSIRVWHGSSKALLMRAAELTRTGIGLPAYYNDEVIIPALVHRGATMDEARNYNIIGCVEPQVPGKTDGWHDAAFFNMCRPLEMVFSNGYDNGEIASIQTGNVESFQSFDEFMEAYRKQMLYNIELMVNADNAIDYAHAKLAPLPFESCLVDDCIKRGMSAQEGGAIYNFTGPQGFGIANVADSLYTIKKLVFEEKRITMGELKKALEMNYGKGPEDVRKRYEEIHEMILELPKYGNDIDEVDELAREAAYFYTRPLETFKNPRGGMYQAGLYPVSANVPLGAQTGATPDGRLAHTPVADGVGPTSGFDISGPTASCNSVAKLDHAIASNGTLFNMKMHPTAMAGEKGLESFISLIRGYFDQQGMHMQFNVVDRATLLDAQAHPEKYSGLIVRVAGYSALFTTLSKSLQDDIIKRTEQ 5i3t A 2.10 BS01 BU2 A 1 Y95 W273 V322 Y64 W242 V291 4.2.1.127,5.4.4.4 E1XUJ2 ELPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPP 5i3t B 2.10 BS01 BU2 E 1 V92 V322 L370 V60 V290 L338 4.2.1.127,5.4.4.4 E1XUJ2 LPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPP 5i3t D 2.10 BS01 BU2 D 1 Y95 Y269 W273 L371 Y63 Y237 W241 L339 4.2.1.127,5.4.4.4 E1XUJ2 LPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPP 5i3t E 2.10 BS01 BU2 E 1 D68 F69 D36 F37 4.2.1.127,5.4.4.4 E1XUJ2 LPPGRLATTEDYFAQQAKQAVTPDVMAQLAYMNYIDFISPFYSRGCSFEAWELKHTPQRVIKYSIAFYAYGLASVALIDPKLRALAGHDLDIAVSKMKCKRVWGDWEEDGFGTDPIEKENIMYKGHLNLMYGLYQLVTGSRRYEAEHAHLTRIIHDEIAANPFAGIVCEPDNYFVQCNSVAYLSLWVYDRLHGTDYRAATRAWLDFIQKDLIDPERGAFYLSYHPESGAVKPWISAYTTAWTLAMVHGMDPAFSERYYPRFKQTFVEVYDEGRKARVRETAGTDDADGGVGLASAFTLLLAREMGDQQLFDQLLNHLEPPAKPSIVSASLRYEHPGSLLFDELLFLAKVHAGFGALLRMPPPA 5i3u A 3.00 BS01 NUC E 1 W24 F61 L74 V75 D76 R78 N81 E89 Q91 L92 I94 D113 Y115 Q151 G152 K154 P157 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 K353 A355 R358 G359 A360 H361 R448 T473 N474 Q475 K476 Q500 Y501 W21 F58 L71 V72 D73 R75 N78 E86 Q88 L89 I91 D110 Y112 Q148 G149 K151 P154 Y180 M181 D182 D183 M227 G228 N252 Q255 K256 G259 K260 W263 V273 S277 R281 G282 K350 A352 R355 G356 A357 H358 R445 T470 N471 Q472 K473 Q497 Y498 2.7.7.49 P03366 27192549 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5i3u C 3.00 BS01 NUC F 1 W24 F61 R72 L74 D76 R78 N81 E89 Q91 L92 I94 D110 D113 A114 Y115 F116 Q151 G152 K154 P157 Q161 Y183 D185 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 T286 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Q500 Y501 W24 F61 R72 L74 D76 R78 N81 E89 Q91 L92 I94 D110 D113 A114 Y115 F116 Q151 G152 K154 P157 Q161 Y183 D185 M230 G231 N255 Q258 K259 G262 K263 W266 V276 S280 R284 G285 T286 K353 A355 G359 A360 H361 K374 R448 T473 Q475 K476 Q500 Y501 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS 5i42 A 3.30 BS03 AZT A 1 K65 R72 D110 V111 G112 D113 A114 Y115 F116 Q151 D185 K220 K65 R72 D110 V111 G112 D113 A114 Y115 F116 Q151 D185 K220 2.7.7.49 P03366 27192549 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 5ih8 A 1.85 BS01 6BJ A 1 E15 I17 L27 A38 C70 L86 E87 Y88 C89 P90 L139 I149 E14 I16 L23 A34 C63 L79 E80 Y81 C82 P83 L132 I142 2.7.11.1 Q14680 27187609 MDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARG 5ih9 A 1.79 BS01 6BF A 1 I17 G18 T19 L27 A38 C70 L86 E87 Y88 C89 P90 E93 L139 I149 I16 G17 T18 L26 A37 C65 L81 E82 Y83 C84 P85 E88 L134 I144 2.7.11.1 Q14680 27187609 MDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARG 5iky A 2.50 BS01 MG A 1 H225 H227 E477 H220 H222 E472 A0A096YSN3 VKTFYITAAPVGAVPKFLDPLEPKFIPHALLELLPADRREATIKALEANGWEAVPAGGIVREYGYDAPIDLTDYASATVHDALRNNGWTPSGSVWHRTQTSPSLAQPPLITRNTLERLSSVDLVRQIVLQLTTFGWTATEDGSLTWAHDRIHTYLSPDFVERMRADNAAVLDSLFENGWRMCGAGHWQPGKARSPYLPITANGIVDASREALREGAAVVHLHTRATDDQATLAIPGLNTPIGIGSQRNHIVLDDYDRIMPTLLDLEPSAILNLSTSARGDRRASQSPLRRAHLKRYGHAQLAPDVASFSPGPVVFQAGGGYDNPNAFLADQLAHFAEVGVRPEIEVFNHTIVENSVTLYQSPLVKAGVPVLFMLVAAVDQYHRDPVSGDTSDDSLIDVPTRKAIAKLLQAGTDDAHEKAVELAATQLRPTVEKLRDNFPSCKISLLLPGPFQALLVDVAIALDLDGIRVGLEDALNVFDARVPGGVRKACGTGDQVRWLRRELERRGIGIVDAETLRDELGMSRPDVALFRQAEAALAHYPADERLVSADTILDALHPIVDTYRKIEDRLAAHLASAPADPAALAEHVLTAARSFGITIRSFVEELDRYEDHEYLVARYIQIPQALNFARELLVPRGYSIEAYDRALEDYSYSVRVDQFKPLPLRCLEYLVGIPCRYNSDYSNVVNLGLRQSPRYSATMALLYHALRELTLELRDRSNASRKACGPLWTVLETVRRDVAPDELAAAIASVDWVVLPSTPTTNYPLGIKLSNGMAQLFHGFVAQIAADPPLRLLAITHSGRRDDGETVIEASMLHNRFALNADPSGIYFSEESQLIYERLILPRLVDKPAKLAYTERQLRINAEQIERLPLLKCFAHSSGIATAQQLDVQACRDGERLGLTGDELRAFFDRALLVSFGSAADIHLDWLGTSVVDVTAFNDVRSLAGTTSRHYVIQPGEHADVLQHCLVHTQPADYRYDHATPVWQDGRQGKIVARLTGVFLLDDHARLDDGHSIRRYLAASPLWLRQWIARFHDAPADTGAHAILRELQ 5ikz A 2.80 BS01 MG A 1 H225 H227 E350 E477 H220 H222 E345 E472 A0A096YSN3 VKTFYITAAPVGAVPKFLDPLEPKFIPHALLELLPADRREATIKALEANGWEAVPAGGIVREYGYDAPIDLTDYASATVHDALRNNGWTPSGSVWHRTQTSPSLAQPPLITRNTLERLSSVDLVRQIVLQLTTFGWTATEDGSLTWAHDRIHTYLSPDFVERMRADNAAVLDSLFENGWRMCGAGHWQPGKARSPYLPITANGIVDASREALREGAAVVHLHTRATDDQATLAIPGLNTPIGIGSQRNHIVLDDYDRIMPTLLDLEPSAILNLSTSARGDRRASQSPLRRAHLKRYGHAQLAPDVASFSPGPVVFQAGGGYDNPNAFLADQLAHFAEVGVRPEIEVFNHTIVENSVTLYQSPLVKAGVPVLFMLVAAVDQYHRDPVSGDTSDDSLIDVPTRKAIAKLLQAGTDDAHEKAVELAATQLRPTVEKLRDNFPSCKISLLLPGPFQALLVDVAIALDLDGIRVGLEDALNVFDARVPGGVRKACGTGDQVRWLRRELERRGIGIVDAETLRDELGMSRPDVALFRQAEAALAHYPADERLVSADTILDALHPIVDTYRKIEDRLAAHLASAPADPAALAEHVLTAARSFGITIRSFVEELDRYEDHEYLVARYIQIPQALNFARELLVPRGYSIEAYDRALEDYSYSVRVDQFKPLPLRCLEYLVGIPCRYNSDYSNVVNLGLRQSPRYSATMALLYHALRELTLELRDRSNASRKACGPLWTVLETRRDVAPDELAAAIASVDWVVLPSTPTTNYPLGIKLSNGMAQLFHGFVAQIAADPPLRLLAITHSGRRDDGETVIEASMLHNRFALNADPSGIYFSEESQLIYERLILPRLVDKPAKLAYTERQLRINAEQIERLPLLKCFAHSSGIATAQQLDVQACRDGERLGLTGDELRAFFDRALLVSFGSAADIHLDWLGTSVVDVTAFNDVRSLAGTTSRHYVIQPGEHADVLQHCLVHTQPADYRYDHATPVWQDGRQGKIVARLTGVFLLDDHARLDDGHSIRRYLAASPLWLRQWIARFHDAPADTGAHAILRELQ 5ikz A 2.80 BS02 GOL A 1 S785 H934 H1069 I1071 S756 H875 H1010 I1012 A0A096YSN3 VKTFYITAAPVGAVPKFLDPLEPKFIPHALLELLPADRREATIKALEANGWEAVPAGGIVREYGYDAPIDLTDYASATVHDALRNNGWTPSGSVWHRTQTSPSLAQPPLITRNTLERLSSVDLVRQIVLQLTTFGWTATEDGSLTWAHDRIHTYLSPDFVERMRADNAAVLDSLFENGWRMCGAGHWQPGKARSPYLPITANGIVDASREALREGAAVVHLHTRATDDQATLAIPGLNTPIGIGSQRNHIVLDDYDRIMPTLLDLEPSAILNLSTSARGDRRASQSPLRRAHLKRYGHAQLAPDVASFSPGPVVFQAGGGYDNPNAFLADQLAHFAEVGVRPEIEVFNHTIVENSVTLYQSPLVKAGVPVLFMLVAAVDQYHRDPVSGDTSDDSLIDVPTRKAIAKLLQAGTDDAHEKAVELAATQLRPTVEKLRDNFPSCKISLLLPGPFQALLVDVAIALDLDGIRVGLEDALNVFDARVPGGVRKACGTGDQVRWLRRELERRGIGIVDAETLRDELGMSRPDVALFRQAEAALAHYPADERLVSADTILDALHPIVDTYRKIEDRLAAHLASAPADPAALAEHVLTAARSFGITIRSFVEELDRYEDHEYLVARYIQIPQALNFARELLVPRGYSIEAYDRALEDYSYSVRVDQFKPLPLRCLEYLVGIPCRYNSDYSNVVNLGLRQSPRYSATMALLYHALRELTLELRDRSNASRKACGPLWTVLETRRDVAPDELAAAIASVDWVVLPSTPTTNYPLGIKLSNGMAQLFHGFVAQIAADPPLRLLAITHSGRRDDGETVIEASMLHNRFALNADPSGIYFSEESQLIYERLILPRLVDKPAKLAYTERQLRINAEQIERLPLLKCFAHSSGIATAQQLDVQACRDGERLGLTGDELRAFFDRALLVSFGSAADIHLDWLGTSVVDVTAFNDVRSLAGTTSRHYVIQPGEHADVLQHCLVHTQPADYRYDHATPVWQDGRQGKIVARLTGVFLLDDHARLDDGHSIRRYLAASPLWLRQWIARFHDAPADTGAHAILRELQ 5ina B 1.79 BS01 ZN B 1 H96 F119 T124 H64 F87 T92 P77754 FKDLNLTDAQKQQIREIMKGQRMRPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT 5ioa B 1.87 BS01 ZN B 1 E87 K90 E52 K55 P77754 FKDLNLTDAQKQQIREIMKGQRLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLALMETQNKIYNILTPEQKKQFNANFEKR 5ioe A 1.87 BS01 GLU A 1 D74 K77 D38 K41 P77754 SFKDLNLTDAQKQQIREIMKPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLALMETQNKIYNILTPEQKKQFNANFEKRL 5ioe B 1.87 BS01 ZN B 1 R62 D66 R27 D31 P77754 FKDLNLTDAQKQQIREIMKRPPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLALMETQNKIYNILTPEQKKQFNANFEKRL 5ioe B 1.87 BS02 ZN B 2 K84 E87 K49 E52 P77754 FKDLNLTDAQKQQIREIMKRPPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLALMETQNKIYNILTPEQKKQFNANFEKRL 5iog B 1.77 BS01 ZN B 1 H96 T124 H61 T89 P77754 FKDLNLTDAQKQQIREIMKGQPLEERRAMHDIIASDTFDKVKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLT 5itz A 2.20 BS01 III D 1 H406 W407 G410 H398 W399 G402 P81947 27219064 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 5itz A 2.20 BS02 GTP A 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 V177 S178 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D90 A91 N93 S132 G135 G136 T137 G138 V169 S170 E175 N198 Y216 N220 I223 P81947 27219064 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVD 5itz B 2.20 BS01 III D 1 Y108 H192 Q193 E196 P263 G412 D414 M416 E417 E420 S423 N424 D427 Y102 H186 Q187 E190 P257 G392 D394 M396 E397 E400 S403 N404 D407 Q6B856 27219064 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNAKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 5itz B 2.20 BS03 LOC B 1 C241 L242 L248 A250 K254 L255 N258 M259 T314 V315 A316 I318 N350 K352 I378 C235 L236 L242 A244 K248 L249 N252 M253 T302 V303 A304 I306 N338 K340 I358 Q6B856 27219064 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNAKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 5j5s A 2.15 BS01 6G3 A 1 F278 V281 A293 I294 K295 L297 M302 F307 E310 A311 M314 I336 T338 E339 Y340 M341 G344 L393 D404 F21 V24 A36 I37 K38 L40 M45 F50 E53 A54 M57 I79 T81 E82 Y83 M84 G87 L136 D147 2.7.10.2 P00523 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5j5s B 2.15 BS01 6G3 B 1 L273 V281 A293 I294 K295 L297 F307 M314 I336 T338 E339 M341 L393 A403 D404 L18 V24 A36 I37 K38 L40 F50 M57 I79 T81 E82 M84 L136 A146 D147 2.7.10.2 P00523 AKDAWEIPRESLRLEVKLGQFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 5jaj A 1.50 BS01 NUC X 1 K138 E139 A140 V257 Q260 R261 H406 S407 N408 M457 N459 R486 R490 M573 H574 F595 M619 S632 I633 K634 K649 W650 S651 K137 E138 A139 V245 Q248 R249 H388 S389 N390 M439 N441 R468 R472 M555 H556 F577 M601 S614 I615 K616 K631 W632 S633 G0YYQ5 27203181 ELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQD 5jaj A 1.50 BS02 NUC Y 1 N55 K56 V57 G82 S85 T103 Q105 I106 N109 Q256 E259 Q260 V263 E264 N267 R285 K373 T374 R375 T402 G403 S404 G405 Q409 T436 S437 V438 E571 M573 H574 R597 F599 W602 K645 K648 N54 K55 V56 G81 S84 T102 Q104 I105 N108 Q244 E247 Q248 V251 E252 N255 R273 K355 T356 R357 T384 G385 S386 G387 Q391 T418 S419 V420 E553 M555 H556 R579 F581 W584 K627 K630 G0YYQ5 27203181 ELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQD 5jaj A 1.50 BS03 ZN A 1 C554 C557 C610 C613 C536 C539 C592 C595 G0YYQ5 27203181 ELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQD 5jaj A 1.50 BS04 ADP A 1 E2 L3 H4 Q7 G27 A28 G29 K30 T31 R32 E67 D444 R471 E1 L2 H3 Q6 G26 A27 G28 K29 T30 R31 E66 D426 R453 G0YYQ5 27203181 ELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQD 5jaj A 1.50 BS05 ALF A 1 T26 G27 K30 E132 G442 R469 R471 T25 G26 K29 E131 G424 R451 R453 G0YYQ5 27203181 ELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQD 5jb8 S 1.45 BS02 0GJ S 1 H57 Y99 D189 S190 C191 Q192 G193 S195 I213 S214 W215 G216 E217 E219 C220 G226 H41 Y86 D179 S180 C181 Q182 G183 S185 I203 S204 W205 G206 E207 E208 C209 G216 3.4.21.22 P00740 27208168 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINTYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT 5jba S 1.40 BS02 0G6 S 1 C42 H57 Y99 F174 D189 S190 C191 Q192 G193 S195 I213 S214 W215 G216 E217 E219 C220 G226 C26 H41 Y86 F162 D179 S180 C181 Q182 G183 S185 I203 S204 W205 G206 E207 E208 C209 G216 3.4.21.22 P00740 27208168 IVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINTYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTITNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGVISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT 5jbc S 1.90 BS02 0G6 S 1 H57 Y99 F174 D189 S190 C191 Q192 G193 S195 V213 S214 W215 G216 E217 E219 C220 G226 H41 Y86 F162 D179 S180 C181 Q182 G183 S185 V203 S204 W205 G206 E207 E208 C209 G216 3.4.21.22 P00740 27208168 IVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINTYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTITNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIVSWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT 5jbg A 2.00 BS01 NUC X 1 N55 K56 V57 A79 V80 S81 G82 S84 H86 K87 C88 F89 F90 L93 T103 Q105 I106 N109 K138 E139 A140 Q256 E259 Q260 R261 V263 E264 N267 R285 K373 T374 R375 T402 G403 S404 G405 H406 S407 N408 T436 S437 V438 M457 N459 R486 R490 M573 H574 I593 F595 R597 T598 F599 R600 R607 M619 S632 K634 K645 K648 K649 W650 S651 N55 K56 V57 A79 V80 S81 G82 S84 H86 K87 C88 F89 F90 L93 T103 Q105 I106 N109 K138 E139 A140 Q248 E251 Q252 R253 V255 E256 N259 R277 K361 T362 R363 T390 G391 S392 G393 H394 S395 N396 T424 S425 V426 M445 N447 R474 R478 M561 H562 I581 F583 R585 T586 F587 R588 R595 M607 S620 K622 K633 K636 K637 W638 S639 G0YYQ5 27203181 SELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQEVPQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQPGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQDES 5jbg A 2.00 BS04 ALF A 1 T26 G27 K30 E132 A168 G442 R469 R471 T26 G27 K30 E132 A168 G430 R457 R459 G0YYQ5 27203181 SELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAQEVPQPTKQYDLCQEREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQPGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANSREVYREQLNESLVGLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQDES 5jbj A 3.58 BS01 NUC X 1 K138 E139 A140 Q256 V257 Q260 R261 H406 K411 M573 H574 F595 W602 R607 G618 M619 I630 S632 K634 K649 W650 K138 E139 A140 Q233 V234 Q237 R238 H378 K383 M530 H531 F552 W559 R564 G575 M576 I587 S589 K591 K606 W607 G0YYQ5 27203181 SELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYNPRLSKLEEILQEHFQPPGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQ 5jbj A 3.58 BS02 NUC Y 1 N55 K56 V57 G82 S85 T103 Q105 N109 E259 Q260 R285 K373 T374 R375 T402 G403 S404 Q409 Q415 T436 S437 V438 E571 M573 H574 R597 F599 W602 K648 N55 K56 V57 G82 S85 T103 Q105 N109 E236 Q237 R262 K345 T346 R347 T374 G375 S376 Q381 Q387 T408 S409 V410 E528 M530 H531 R554 F556 W559 K605 G0YYQ5 27203181 SELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYNPRLSKLEEILQEHFQPPGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQ 5jbj A 3.58 BS03 ZN A 1 C554 C557 C610 C613 C511 C514 C567 C570 G0YYQ5 27203181 SELHGYQLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLEGRRGGRVAVLVNKVHLVQQHLEKEFHVLRDAFKVTAVSGDSSHKCFFGQLAKGSDVVICTAQILQNALLSGEEEARVELTDFSLLVIDECHHTQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTASPGTGGETSFEGAVEHILQICANLDTEVIASAREQDPFGQRLKKIMAQIQEHMEMPELPQNFGTQVYEQRIVELENRAAERFCRKTRVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENRATLQALAGDQRYNPRLSKLEEILQEHFQPPGSSRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRARAQNSMYSVLAKANLMERAIRAVQAMPERKYRLKIVELQRNAVLSWQVKEARSSERRQLHDPDDVYFHCVNCNVAVCRGSDIRTVEAMHHVNINPNFRFYYTVSSGKIHFERTFRDWEPGCRIVCSECRQEWGMEMIYRNVTLPILSIKNFVVVTPDEKKKYKKWSTVTFPIEEFSYLEYCSSTQ 5jc3 A 2.60 BS01 NUC X 1 Q441 K442 E443 G444 Q568 Q572 H733 T785 N786 R817 K861 M900 K978 W979 G980 Q143 K144 E145 G146 Q267 Q271 H427 T479 N480 R511 K555 M592 K658 W659 G660 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRKTKNPSLITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENYQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jc3 A 2.60 BS02 NUC Y 1 N357 K358 V359 S384 G385 D386 T406 Q408 N412 E571 I575 K700 T701 R702 I729 G730 A731 S735 E736 Q745 T763 T764 V765 K977 N61 K62 V63 S88 G89 D90 T110 Q112 N116 E270 I274 K394 T395 R396 I423 G424 A425 S429 E430 Q439 T457 T458 V459 K657 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRKTKNPSLITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENYQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jc3 A 2.60 BS03 ADP A 1 T300 R302 Q305 T324 G325 S326 G327 K328 R330 E369 R798 T4 R6 Q9 T28 G29 S30 G31 K32 R34 E73 R492 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRKTKNPSLITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENYQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jc3 A 2.60 BS04 ZN A 1 C881 C884 C936 C939 C573 C576 C619 C622 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRKTKNPSLITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENYQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jc3 B 2.60 BS01 NUC C 1 Q441 K442 E443 G444 Q568 Q572 H733 T785 N786 R817 K861 M900 H901 W979 Q143 K144 E145 G146 Q267 Q271 H427 T479 N480 R511 K555 M585 H586 W652 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENYQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jc7 A 2.75 BS01 NUC X 1 K442 E443 G444 K562 Q568 P569 Q572 H733 V784 T785 N786 R817 K861 M900 H901 K958 K978 K140 E141 G142 K250 Q256 P257 Q260 H413 V464 T465 N466 R497 K541 M571 H572 K614 K630 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETKEIFKKWGELPIIFPDF 5jc7 A 2.75 BS02 NUC Y 1 N357 V359 G385 T406 Q408 I409 N412 E571 I575 K700 T701 R702 I729 G730 A731 S735 Q742 T763 T764 V765 R864 E898 K977 N60 V62 G88 T109 Q111 I112 N115 E259 I263 K380 T381 R382 I409 G410 A411 S415 Q422 T443 T444 V445 R544 E569 K629 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETKEIFKKWGELPIIFPDF 5jc7 A 2.75 BS03 ZN A 1 C881 C884 C936 C939 C552 C555 C592 C595 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETKEIFKKWGELPIIFPDF 5jc7 A 2.75 BS04 ADP A 1 R302 Q305 P323 G325 G327 K328 R330 E369 R798 R5 Q8 P26 G28 G30 K31 R33 E72 R478 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETKEIFKKWGELPIIFPDF 5jc7 B 2.75 BS01 NUC X 1 N357 K358 V359 S384 G385 T406 Q408 N412 E571 Q572 K700 T701 R702 I729 G730 A731 S735 Q742 T763 T764 V765 R864 E898 K977 N60 K61 V62 S87 G88 T109 Q111 N115 E259 Q260 K383 T384 R385 I412 G413 A414 S418 Q425 T446 T447 V448 R547 E572 K633 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESPLVSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETTKEIFKKWGELPIIFPDFDY 5jc7 B 2.75 BS02 NUC Y 1 Q441 K442 E443 G444 K562 Q568 P569 Q572 H733 V784 T785 N786 R817 K861 M900 H901 K978 Q139 K140 E141 G142 K250 Q256 P257 Q260 H416 V467 T468 N469 R500 K544 M574 H575 K634 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESPLVSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETTKEIFKKWGELPIIFPDFDY 5jc7 B 2.75 BS04 ADP B 1 T300 R302 Q305 P323 G325 G327 K328 R330 E369 R798 T3 R5 Q8 P26 G28 G30 K31 R33 E72 R481 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESPLVSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKREEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFETTKEIFKKWGELPIIFPDFDY 5jcf A 2.60 BS01 NUC X 1 Q441 K442 E443 G444 Q568 Q572 H733 T785 N786 R817 K861 M900 Q143 K144 E145 G146 Q267 Q271 H427 T479 N480 R511 K555 M585 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jcf A 2.60 BS03 ADP A 1 T300 R302 Q305 T324 G325 G327 K328 R330 R798 T4 R6 Q9 T28 G29 G31 K32 R34 R492 D9N195 27203181 GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jch A 2.95 BS02 NUC Y 1 N357 K358 V359 P360 G385 T406 Q408 N412 E571 K700 T701 R702 G730 A731 S735 Q745 T763 T764 V765 R864 K977 N60 K61 V62 P63 G88 T109 Q111 N115 E266 K389 T390 R391 G419 A420 S424 Q434 T452 T453 V454 R553 K650 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRKKNPSLITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jch A 2.95 BS04 ADP A 1 T300 R302 Q305 G325 G327 K328 T329 R330 E369 T3 R5 Q8 G28 G30 K31 T32 R33 E72 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRKKNPSLITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jch B 2.95 BS01 NUC U 1 K442 E443 G444 Q568 Q572 H733 T785 N786 R817 M900 H901 W979 K140 E141 G142 Q263 Q267 H422 T474 N475 R506 M580 H581 W646 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jch B 2.95 BS02 NUC V 1 N357 K358 V359 P360 S384 G385 D386 T406 Q408 N412 E571 K700 T701 R702 I729 G730 A731 S735 Q745 T763 T764 V765 R864 K977 N60 K61 V62 P63 S87 G88 D89 T109 Q111 N115 E266 K389 T390 R391 I418 G419 A420 S424 Q434 T452 T453 V454 R553 K644 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jch B 2.95 BS04 ADP B 1 T300 R302 Q305 G325 S326 G327 K328 T329 R330 E369 T3 R5 Q8 G28 S29 G30 K31 T32 R33 E72 D9N195 27203181 DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDSKQDETDEFLMRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELPIIFPD 5jp4 A 2.04 BS01 III B 1 V90 R97 V89 R96 Q9P805 EDENILRNAVNLQVLKFHYPEIESIIDIASHVAVYQFDVGSQKWLKTSIEGTFFLVKDQRARVGYVILNRNSPENLYLFINHPSNVHLVDRYLIHRTENQHVVGLWMFDPNDMSRIFNIVKESLLR 5jp4 A 2.04 BS02 III B 2 A34 Y36 F38 W45 L46 K47 V90 Y93 R97 Q101 V103 W107 A33 Y35 F37 W44 L45 K46 V89 Y92 R96 Q100 V102 W106 Q9P805 EDENILRNAVNLQVLKFHYPEIESIIDIASHVAVYQFDVGSQKWLKTSIEGTFFLVKDQRARVGYVILNRNSPENLYLFINHPSNVHLVDRYLIHRTENQHVVGLWMFDPNDMSRIFNIVKESLLR 5jp6 A 1.50 BS01 ZN A 1 D177 H227 Y280 D155 H205 Y240 3.5.1.- Q6MI90 27211869 MSQIGSSVRQAVSDNQSAQTLVEWENSEANPEALFANWRHEFMVDSSKRESMKTELCKELQALPAQDLTLFENEIRDENNRALVSGCKEELLAQVDEHFDEQRESMSVPGHALKAVQSRNSFRFPDNTQKRDMSNGYMAVRGDVARKEVVLTFDDGPHGLYTDAILRALKEVNAKAMFFATGKSVRTNPEALKRVAADGHVIGSHSITLTFDEAAAEVRGGHQAVFDVLGWVDPVFRFPYGETSKDLKAFLKTKSTGEFAWNIESDDWRTQSNEQLLARVLANVESQGRGIVLFHDIQRRTAEIMPQFLRELYNRGYSVVLLTAADPSAKYNSKLVKRK 5jp6 A 1.50 BS02 MG A 1 M155 A364 A365 D366 M133 A324 A325 D326 3.5.1.- Q6MI90 27211869 MSQIGSSVRQAVSDNQSAQTLVEWENSEANPEALFANWRHEFMVDSSKRESMKTELCKELQALPAQDLTLFENEIRDENNRALVSGCKEELLAQVDEHFDEQRESMSVPGHALKAVQSRNSFRFPDNTQKRDMSNGYMAVRGDVARKEVVLTFDDGPHGLYTDAILRALKEVNAKAMFFATGKSVRTNPEALKRVAADGHVIGSHSITLTFDEAAAEVRGGHQAVFDVLGWVDPVFRFPYGETSKDLKAFLKTKSTGEFAWNIESDDWRTQSNEQLLARVLANVESQGRGIVLFHDIQRRTAEIMPQFLRELYNRGYSVVLLTAADPSAKYNSKLVKRK 5jr3 A 1.84 BS01 SAH A 1 Y143 R153 L160 G187 G189 E210 M211 G236 D237 F238 S252 F253 N257 W258 Y133 R143 L150 G177 G179 E200 M201 G226 D227 F228 S242 F243 N247 W248 2.1.1.292 Q06528 PQQIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRLPDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLPRKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPAA 5jr3 A 1.84 BS02 4MU A 1 F156 L160 F253 L300 R303 F146 L150 F243 L290 R293 2.1.1.292 Q06528 PQQIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRLPDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLPRKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPAA 5jr3 B 1.84 BS02 4MU B 1 F156 F253 L300 R303 F144 F241 L288 R291 2.1.1.292 Q06528 QIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRLPDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLPRKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPA 5jr3 C 1.84 BS02 4MU C 1 F156 L160 L300 R303 M304 F147 L151 L291 R294 M295 2.1.1.292 Q06528 RPQQIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRLPDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLPRKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPAA 5jwz A 1.70 BS01 CA A 1 D435 L479 D428 L472 G2NK78 DTYTWKNARIDGGGFVPGIVFNRSEKNLAYARTDIGGAYRWDQSGKQWKPLLDWVDWDRWGWTGVVSLASDTVDPDNVYAAVGTYTNSWDPTDGAVLRSSDRGASWKAATLPFKLGGNMPGRGMGERLAVDPNKNSVLYLGAPSGNGLWRSTDAGVSWSEVTAFPNPGNYAQDPSDTSGYGNDNQGIVWVTFDERSGSAGSATQDIYVGVADKENTVYRSTDGGATWSRIPGQPTGYLAHKGVLDSATGHLYLTLSDTGGPYDGGKGRIWRYDTASGAWQDVSPVAEADAYYGFSGLSVDRQKPGTLMATAYSSWWPDTQIFRSTDSGATWTQAWDYTGYPNRSNRYTLDVSSVPWLSWGASPAPPETAPKLGWMTEALEIDPFDSDRMMYGTGATVYGTEDLTSWDSGGTFRITPMVKGIEETAVNDLASPPSGAPLLSALGDIGGFRHTDLDAVPDLMYTSPNLDSTTSLDFAESSPGTVVRVGNSDAAPHIGFSTDNGANWFQGSEPSGVTGGGTVAAAADGSGFVWSPEGAGVHHTTGFGTSWTASTGIPAGATVESDRKNPEKFYGFEAGTFYVSTDGGATFTAEATGLPAEGNVRFQALPGTEGDIWLAGGSDTGAYGLWRSTDSGATFTKSAGVEQADSVGFGKAAPGASYRTVFVSAKIGGVRGIFRSTDAGASWTRINDDAHQWGWTGAAITGDPRVYGRVYVSTNGRGIQVGET 5jwz A 1.70 BS02 CA A 2 D180 S182 D173 S175 G2NK78 DTYTWKNARIDGGGFVPGIVFNRSEKNLAYARTDIGGAYRWDQSGKQWKPLLDWVDWDRWGWTGVVSLASDTVDPDNVYAAVGTYTNSWDPTDGAVLRSSDRGASWKAATLPFKLGGNMPGRGMGERLAVDPNKNSVLYLGAPSGNGLWRSTDAGVSWSEVTAFPNPGNYAQDPSDTSGYGNDNQGIVWVTFDERSGSAGSATQDIYVGVADKENTVYRSTDGGATWSRIPGQPTGYLAHKGVLDSATGHLYLTLSDTGGPYDGGKGRIWRYDTASGAWQDVSPVAEADAYYGFSGLSVDRQKPGTLMATAYSSWWPDTQIFRSTDSGATWTQAWDYTGYPNRSNRYTLDVSSVPWLSWGASPAPPETAPKLGWMTEALEIDPFDSDRMMYGTGATVYGTEDLTSWDSGGTFRITPMVKGIEETAVNDLASPPSGAPLLSALGDIGGFRHTDLDAVPDLMYTSPNLDSTTSLDFAESSPGTVVRVGNSDAAPHIGFSTDNGANWFQGSEPSGVTGGGTVAAAADGSGFVWSPEGAGVHHTTGFGTSWTASTGIPAGATVESDRKNPEKFYGFEAGTFYVSTDGGATFTAEATGLPAEGNVRFQALPGTEGDIWLAGGSDTGAYGLWRSTDSGATFTKSAGVEQADSVGFGKAAPGASYRTVFVSAKIGGVRGIFRSTDAGASWTRINDDAHQWGWTGAAITGDPRVYGRVYVSTNGRGIQVGET 5jxs A 2.80 BS01 NUC B 1 L108 D109 T115 A116 R128 F162 L163 D165 V181 V183 I189 R193 H204 A216 A217 N218 S298 G299 C300 S301 A302 T303 S304 Y336 R416 L108 D109 T115 A116 R128 F162 L163 D165 V181 V183 I189 R193 H204 A216 A217 N218 S298 G299 C300 S301 A302 T303 S304 Y336 R416 2.7.7.48 P03311 27194768 GLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGVVLDEVIFSKHKGDTKMSAEDKALFRRCAADYASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFACQTFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTRMMIGRFCAQMHSNNGPQIGSAVAANPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCSDAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVEGGMPSGCSATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYKPVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDAAAALEH 5jxs A 2.80 BS02 NUC C 1 D114 Y336 G337 D338 D339 L386 K387 R388 M403 I411 R416 T419 E422 K423 S426 V427 L430 D114 Y336 G337 D338 D339 L386 K387 R388 M403 I411 R416 T419 E422 K423 S426 V427 L430 2.7.7.48 P03311 27194768 GLIVDTRDVEERVHVMRKTKLAPTVAHGVFNPEFGPAALSNKDPRLNEGVVLDEVIFSKHKGDTKMSAEDKALFRRCAADYASRLHSVLGTANAPLSIYEAIKGVDGLDAMEPDTAPGLPWALQGKRRGALIDFENGTVGPEVEAALKLMEKREYKFACQTFLKDEIRPMEKVRAGKTRIVDVLPVEHILYTRMMIGRFCAQMHSNNGPQIGSAVAANPDVDWQRFGTHFAQYRNVWDVDYSAFDANHCSDAMNIMFEEVFRTEFGFHPNAEWILKTLVNTEHAYENKRITVEGGMPSGCSATSIINTILNNIYVLYALRRHYEGVELDTYTMISYGDDIVVASDYDLDFEALKPHFKSLGQTITPADKSDKGFVLGHSITDVTFLKRHFHMDYGTGFYKPVMASKTLEAILSFARRGTIQEKLISVAGLAVHSGPDEYRRLFEPFQGLFEIPSYRSLYLRWVNAVCGDAAAALEH 5k5q B 2.65 BS02 NUC N 1 G2 K3 I4 S5 K29 A30 Y41 Q42 I45 R49 I66 Y68 G1 K2 I3 S4 K28 A29 Y40 Q41 I44 R48 I65 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ