3j9d A 3.50 BS01 ZN A 1 C162 H164 C617 C851 C162 H164 C402 C636 B7U676 MDELGIPVYKRGFPEHLLRGYEFIIDVGTKIESVGGRHDVTKIPEMNAYDIKQESIRTALWYNPIRNDGFVLPRVLDITLRGYDERRAVVESTRHKSFHTNDQWVQWMMKDSMDAQPLKVGLDDQSRNVAHSLHNCVVKIDSKKADTMSYHVEPIEDASKGCLHTRTMMWNHLVRIETFHAAQEVAYTLKYIYGRVNLFDFVAEPGIKIVHWEYRLNHSTREITYAQGNPCDLYPEDDDVIVTKFDDVAYGQMINEMINGGWNQEQFKMHKILKSEGNVLTIDFEKDAKLTTNEGVTMPEYFNKWIIAPMFNAKLRIKHEEIAQRQSDDPMVKRTLSPITADPIELQRLTLARFYDIRPALRGQALSRQQAQSTYDEEISKRQDYAEILKRRGIVQIPKKPCPTVTAQYTLERYALFIISILQQHVVRDCDEEAVYEHPKADHELEIFGESIVDISQVIILAFDLIFERRRRVRDVYESRHIIARIRRMRGKERLNVIAEFFPTYGGLLNGLNSATVVQNIMYLNFLPLYFLVGDNMIYSHRQWSIPLLLYTHEVMVVPLEVGSYNDRCGLIAYLEYMVFFPSKAIRFSKLNEAQPKIAREMLKYYANTTVYDGGVNYNVVTTKQLLYETYLASLCGGISDGIVWYLPITHPNKCIVAIEVSDERVPASIRAGRIRLRFPLSARHLKGVVIIQIDEEGEFTVYSEGIVSHRVCKKNLLKYMCDIILLKFSGHVFGNDEMLTKLLNV 3jbw A 4.63 BS01 NUC E 1 G408 G409 R410 P411 S496 C497 S498 Q499 K502 R523 M996 N997 A998 R999 D1008 K1011 G1 G2 R3 P4 S89 C90 S91 Q92 K95 R116 M589 N590 A591 R592 D601 K604 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw A 4.63 BS02 NUC F 1 G409 R410 R412 L418 R421 K424 H425 R426 H501 K508 H520 K628 H629 G630 S631 Q1000 G2 R3 R5 L11 R14 K17 H18 R19 H94 K101 H113 K221 H222 G223 S224 Q593 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw A 4.63 BS03 NUC G 1 N462 E463 D620 G623 D624 K638 D730 A742 G744 S745 T746 R795 M869 R870 N872 G873 N874 R878 E981 E984 S985 K988 R991 N55 E56 D213 G216 D217 K231 D323 A335 G337 S338 T339 R388 M462 R463 N465 G466 N467 R471 E574 E577 S578 K581 R584 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw A 4.63 BS04 NUC H 1 R459 K667 N669 S670 R877 P913 R916 S917 D923 E981 S985 R52 K260 N262 S263 R470 P506 R509 S510 D516 E574 S578 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw A 4.63 BS05 NUC J 1 D730 E731 K732 S743 G744 R756 H817 R845 R870 K953 T955 N956 Y957 D323 E324 K325 S336 G337 R349 H410 R438 R463 K546 T548 N549 Y550 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw A 4.63 BS06 ZN A 1 C749 C752 H959 H964 C342 C345 H552 H557 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw B 4.63 BS01 NUC G 1 K38 R39 S40 N117 R118 K38 R39 S40 N117 R118 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbw B 4.63 BS02 NUC J 1 N10 K56 R58 K119 N10 K56 R58 K119 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbw C 4.63 BS01 NUC E 1 R459 A460 K667 N669 S670 E671 L672 R877 P913 R916 E981 S985 R52 A53 K260 N262 S263 E264 L265 R470 P506 R509 E574 S578 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw C 4.63 BS02 NUC F 1 H464 K465 D620 G621 M622 G623 K638 A742 S745 T746 R795 I820 R870 N872 G873 N874 R878 E981 E984 S985 K988 R991 H57 K58 D213 G214 M215 G216 K231 A335 S338 T339 R388 I413 R463 N465 G466 N467 R471 E574 E577 S578 K581 R584 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw C 4.63 BS03 NUC G 1 G409 R410 R412 L418 R421 A422 R426 K508 H520 K628 H629 G630 S631 Q1000 S1001 G2 R3 R5 L11 R14 A15 R19 K101 H113 K221 H222 G223 S224 Q593 S594 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw C 4.63 BS04 NUC H 1 G409 R410 P411 R420 R421 K424 R428 S496 C497 S498 Q499 K502 R523 M996 A998 R999 Q1000 K1011 G2 R3 P4 R13 R14 K17 R21 S89 C90 S91 Q92 K95 R116 M589 A591 R592 Q593 K604 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw C 4.63 BS05 NUC I 1 D730 E731 K732 S743 G744 R756 H817 R870 R949 K953 T955 N956 Y957 D323 E324 K325 S336 G337 R349 H410 R463 R542 K546 T548 N549 Y550 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw C 4.63 BS06 ZN C 1 C749 C752 H959 H964 C342 C345 H552 H557 3.1.-.-,6.3.2.- O13033 26548953 GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbw D 4.63 BS01 NUC F 1 K38 R39 S40 R118 K38 R39 S40 R118 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbw D 4.63 BS02 NUC I 1 N10 R49 K56 R58 N117 K119 N10 R49 K56 R58 N117 K119 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbx A 3.40 BS01 NUC E 1 S496 C497 S498 Q499 K502 R523 M996 N997 A998 R999 Q1000 D1008 K1011 S17 C18 S19 Q20 K23 R44 M517 N518 A519 R520 Q521 D529 K532 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS02 NUC F 1 H501 Y504 K508 H520 K628 H629 G630 S631 K995 Q1000 S1001 H22 Y25 K29 H41 K149 H150 G151 S152 K516 Q521 S522 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS03 NUC G 1 L816 N872 G873 N874 R878 E981 E984 S985 N987 K988 R991 L337 N393 G394 N395 R399 E502 E505 S506 N508 K509 R512 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS04 NUC H 1 K667 N669 S670 L672 N874 R877 P913 R916 S917 T918 D923 E981 S985 K188 N190 S191 L193 N395 R398 P434 R437 S438 T439 D444 E502 S506 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS05 NUC I 1 A742 S745 T746 M869 R870 A263 S266 T267 M390 R391 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS06 NUC J 1 D730 E731 K732 S743 G744 R756 H817 R845 R870 K953 T955 N956 Y957 D251 E252 K253 S264 G265 R277 H338 R366 R391 K474 T476 N477 Y478 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS07 ZN A 1 C749 C752 H959 H964 C270 C273 H480 H485 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS08 MG A 1 D620 G621 E984 D141 G142 E505 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx A 3.40 BS09 MG A 2 G621 E684 D730 G142 E205 D251 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx B 3.40 BS01 NUC I 1 K38 R39 S40 R118 K38 R39 S40 R118 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbx B 3.40 BS02 NUC J 1 R49 K56 R58 C116 N117 K119 R49 K56 R58 C116 N117 K119 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbx C 3.40 BS01 NUC E 1 K667 N669 S670 L672 N874 R877 P913 R916 S917 T918 D923 E981 S985 K188 N190 S191 L193 N395 R398 P434 R437 S438 T439 D444 E502 S506 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS02 NUC F 1 M622 L816 R870 N872 G873 N874 E981 E984 S985 N987 K988 R991 M143 L337 R391 N393 G394 N395 E502 E505 S506 N508 K509 R512 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS03 NUC G 1 H501 Y504 K508 H520 S626 K628 H629 G630 S631 R994 K995 Q1000 S1001 H22 Y25 K29 H41 S147 K149 H150 G151 S152 R515 K516 Q521 S522 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS04 NUC H 1 S496 C497 S498 Q499 K502 R523 M996 N997 A998 R999 Q1000 K1011 S17 C18 S19 Q20 K23 R44 M517 N518 A519 R520 Q521 K532 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS05 NUC K 1 E741 A742 S745 T746 R795 M869 R870 E262 A263 S266 T267 R316 M390 R391 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS06 NUC L 1 D730 E731 K732 S743 G744 R756 H817 R845 R870 K953 I954 T955 N956 Y957 D251 E252 K253 S264 G265 R277 H338 R366 R391 K474 I475 T476 N477 Y478 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS07 ZN C 1 C749 C752 H959 H964 C270 C273 H480 H485 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS08 MG C 1 D620 G621 D730 E984 D141 G142 D251 E505 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx C 3.40 BS09 MG C 2 G621 E684 D730 G142 E205 D251 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jbx D 3.40 BS01 NUC K 1 K38 R39 R118 K38 R39 R118 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jbx D 3.40 BS02 NUC L 1 N10 R49 R58 C116 N117 K119 N10 R49 R58 C116 N117 K119 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jby A 3.70 BS01 NUC E 1 S496 C497 S498 Q499 K502 R523 M996 N997 A998 R999 Q1000 D1008 K1011 S17 C18 S19 Q20 K23 R44 M517 N518 A519 R520 Q521 D529 K532 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS02 NUC F 1 Y504 K508 H520 K628 H629 G630 Q1000 Y25 K29 H41 K149 H150 G151 Q521 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS03 NUC G 1 G623 K638 A742 S745 T746 R795 L816 M869 R870 N872 G873 N874 R878 E981 E984 S985 K988 R991 G144 K159 A263 S266 T267 R316 L337 M390 R391 N393 G394 N395 R399 E502 E505 S506 K509 R512 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS04 NUC H 1 K667 N669 S670 L672 R877 P913 R916 S917 D923 E981 S985 K188 N190 S191 L193 R398 P434 R437 S438 D444 E502 S506 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS05 NUC I 1 D730 E731 K732 S743 G744 R756 H817 R870 K953 T955 N956 Y957 D251 E252 K253 S264 G265 R277 H338 R391 K474 T476 N477 Y478 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS06 ZN A 1 C749 C752 H959 H964 C270 C273 H480 H485 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS07 CA A 1 D620 G621 E984 N987 D141 G142 E505 N508 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby A 3.70 BS08 CA A 2 D620 E684 D730 D141 E205 D251 3.1.-.-,6.3.2.- O13033 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby B 3.70 BS01 NUC G 1 K38 R39 S40 N117 R118 K38 R39 S40 N117 R118 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jby B 3.70 BS02 NUC I 1 N10 K56 R58 N117 K119 N10 K56 R58 N117 K119 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jby C 3.70 BS01 NUC E 1 K667 N669 S670 L672 R877 P913 R916 S917 E981 S985 K188 N190 S191 L193 R398 P434 R437 S438 E502 S506 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS02 NUC F 1 M622 G623 K638 A742 S745 T746 R795 M869 R870 N872 G873 N874 E981 E984 S985 K988 M143 G144 K159 A263 S266 T267 R316 M390 R391 N393 G394 N395 E502 E505 S506 K509 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS03 NUC G 1 Y504 K508 H520 K628 H629 G630 Q1000 Y25 K29 H41 K149 H150 G151 Q521 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS04 NUC H 1 S496 C497 S498 Q499 K502 R523 M996 N997 A998 R999 Q1000 K1011 S17 C18 S19 Q20 K23 R44 M517 N518 A519 R520 Q521 K532 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS05 NUC J 1 D730 E731 K732 S743 H817 R870 T955 N956 Y957 D251 E252 K253 S264 H338 R391 T476 N477 Y478 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS06 ZN C 1 C749 C752 H959 H964 C270 C273 H480 H485 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS07 CA C 1 D620 G621 E984 N987 D141 G142 E505 N508 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby C 3.70 BS08 CA C 2 D620 E684 D730 D141 E205 D251 3.1.-.-,6.3.2.- 26548953 GLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAHK 3jby D 3.70 BS01 NUC F 1 K38 R39 S40 R118 K38 R39 S40 R118 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3jby D 3.70 BS02 NUC J 1 N10 R49 K56 R58 N117 K119 N10 R49 K56 R58 N117 K119 Q1RLW7 26548953 MSLQPLTAVNCGSLVQPGFSLLDLEGDVYLFGQKGWPKRSCPTGIFGVRIKKGELKLRAISFSNNSSYLPPLRCPAIAHFEAQDGKPECYLIHGGRTPNNELSSSLYMLSVDSRGCNRKVTLRCEEKELVGDVPSARYGHTLSVINSRGKTACVLFGGRSYMPPTERTTQNWNSVVDCPPQVYLIDLEFGCCTAHTLPELTDGQSFHVALARQDCVYFLGGHILSSDCRPSRLIRLHVELLLGSPVLTCTILHEGLTITSAIASPIGYHEYIIFGGYQSETQKRMECTYVGLDDVGVHMESREPPQWTSEISHSRTWFGGSLGKGTALVAIPSEGNPTPPEAYHFYQVSFQ 3x3m A 1.90 BS01 CA A 1 S106 H295 S109 H298 I6Y4Q7 26396239 PHMGTSLFTDRATNQLYVLLSGQLHPVYNLTSARLVLGNPANPATVKSSELSKLPMGQTVGIPGAPYATPVSAGSTSIWTLCDTVARADSTSPVVQTAVIAMPLEIDASIDPLQSHEAVLVSYQGETWIVTTKGRHAIDLTDRALTSSMGIPVTARPTPISEGMFNALPDMGPWQLPPIPAAGAPNSLGLPDDLVIGSVFQIHTDKGPQYYVVLPDGIAQVNATTAAALRATQAHGLVAPPAMVPSLVVRIAERVYPSPLPDEPLKIVSRPQDPALCWSWQRSAGDQSPQSTVLSGRHLPISPSAMNMGIKQIHGTATVYLDGGKFVALQSPDPRYTESMYYIDPQGVRYGVPNAETAKSLGLSSPQNAPWEIVRLLVDGPVLSKDAALLEHDTLPA 3x3n A 2.00 BS01 CA A 1 S106 H295 S113 H302 I6Y4Q7 26396239 LFQGPHMGTSLFTDRATNQLYVLLSGQLHPVYNLTSARLVLGNPANPATVKSSELSKLPMGQTVGIPGAPYATPVSAGSTSIWTLCDTVARADSTSPVVQTAVIAMPLEIDASIDPLQSHEAVLVSYQGETWIVTTKGRHAIDLTDRALTSSMGIPVTARPTPISEGMFNALPDMGPWQLPPIPAAGAPNSLGLPDDLVIGSVFQIHTDKGPQYYVVLPDGIAQVNATTAAALRATQAHGLVAPPAMVPSLVVRIAERVYPSPLPDEPLKIVSRPQDPALCWSWQRSAGDQSPQSTVLSGRHLPISPSAMNMGIKQIHGTATVYLDGGKFVALSMYYIDPQGVRYGVPNAETAKSLGLSSPQNAPWEIVRLLVDGPVLSKDAAL 4p5a A 1.76 BS01 FAD A 1 R86 H87 R88 T89 H188 L192 R193 H204 R73 H74 R75 T76 H175 L179 R180 H191 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTAGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a A 1.76 BS02 5BU A 1 M85 E94 E95 S96 A97 R98 R166 M72 E81 E82 S83 A84 R85 R153 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTAGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a A 1.76 BS03 5BU B 1 R82 H83 R86 Y124 R193 R69 H70 R73 Y111 R180 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTAGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a A 1.76 BS04 FAD B 1 N93 E94 N80 E81 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTAGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a A 1.76 BS05 FAD C 1 H61 S63 E66 T89 N182 R184 H48 S50 E53 T76 N169 R171 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTAGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a B 1.76 BS01 FAD A 1 N93 E94 S96 N81 E82 S84 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a B 1.76 BS02 5BU A 1 R82 H83 R86 Y124 R193 R70 H71 R74 Y112 R181 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a B 1.76 BS03 5BU B 1 E94 E95 S96 A97 R98 R166 E82 E83 S84 A85 R86 R154 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a B 1.76 BS04 FAD B 1 R86 H87 R88 T89 H188 L192 R193 H204 R74 H75 R76 T77 H176 L180 R181 H192 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a B 1.76 BS05 FAD D 1 H61 S63 E66 T89 N182 R184 H49 S51 E54 T77 N170 R172 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a C 1.76 BS01 FAD A 1 H61 S63 E66 T89 N182 R184 H45 S47 E50 T73 N166 R168 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a C 1.76 BS02 FAD C 1 R86 H87 R88 T89 H188 L192 R193 H204 R70 H71 R72 T73 H172 L176 R177 H188 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a C 1.76 BS03 5BU C 1 M85 E94 E95 S96 A97 R98 R166 M69 E78 E79 S80 A81 R82 R150 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a C 1.76 BS04 5BU D 1 R82 H83 R86 Y124 R193 R66 H67 R70 Y108 R177 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a C 1.76 BS05 FAD D 1 N93 E94 S96 N77 E78 S80 2.1.1.148 C1IC19 PRIELRSDITVELVDSSASDLAVVKAARVSTSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a D 1.76 BS01 FAD B 1 H61 S63 E66 T89 N182 R184 H47 S49 E52 T75 N168 R170 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a D 1.76 BS02 FAD C 1 N93 E94 N79 E80 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a D 1.76 BS03 5BU C 1 R82 H83 R86 Y124 R193 R68 H69 R72 Y110 R179 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a D 1.76 BS04 5BU D 1 M85 E94 E95 S96 A97 R98 R166 M71 E80 E81 S82 A83 R84 R152 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5a D 1.76 BS05 FAD D 1 R86 H87 R88 T89 H188 L192 R193 R72 H73 R74 T75 H174 L178 R179 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b A 2.27 BS01 FAD A 1 R86 H87 R88 H188 L192 R193 S203 H204 R77 H78 R79 H178 L182 R183 S193 H194 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLREGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b A 2.27 BS02 BRU A 1 M85 E94 E95 S96 A97 R98 Y99 R166 M76 E85 E86 S87 A88 R89 Y90 R156 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLREGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b A 2.27 BS03 BRU B 1 H83 R86 R193 H74 R77 R183 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLREGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b A 2.27 BS04 FAD B 1 N93 E94 N84 E85 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLREGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b A 2.27 BS05 FAD C 1 S33 H61 S63 E66 T89 N182 R184 S28 H52 S54 E57 T80 N172 R174 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLREGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b B 2.27 BS01 FAD A 1 N93 E94 S96 N89 E90 S92 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b B 2.27 BS02 BRU A 1 H83 R86 R193 H79 R82 R189 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b B 2.27 BS03 BRU B 1 M85 E94 E95 S96 A97 R98 Y99 R166 M81 E90 E91 S92 A93 R94 Y95 R162 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b B 2.27 BS04 FAD B 1 R86 H87 R88 T89 H188 L192 R193 S203 H204 R82 H83 R84 T85 H184 L188 R189 S199 H200 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b B 2.27 BS05 FAD D 1 S33 H61 S63 E66 T89 N182 R184 S29 H57 S59 E62 T85 N178 R180 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b C 2.27 BS01 FAD A 1 S33 S63 E66 T89 N182 R184 S28 S58 E61 T84 N177 R179 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b C 2.27 BS02 FAD C 1 R86 H87 R88 T89 H188 L192 R193 R81 H82 R83 T84 H183 L187 R188 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b C 2.27 BS03 BRU C 1 M85 E94 E95 S96 A97 R98 Y99 R166 M80 E89 E90 S91 A92 R93 Y94 R161 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b C 2.27 BS04 BRU D 1 H83 R86 R193 H78 R81 R188 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b C 2.27 BS05 FAD D 1 N93 E94 N88 E89 2.1.1.148 C1IC19 IELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b D 2.27 BS01 FAD B 1 S33 S63 T89 N182 R184 S29 S59 T85 N178 R180 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b D 2.27 BS02 FAD C 1 N93 E94 S96 N89 E90 S92 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b D 2.27 BS03 BRU C 1 H83 R86 R193 H79 R82 R189 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b D 2.27 BS04 BRU D 1 M85 E94 E95 S96 A97 R98 Y99 R166 M81 E90 E91 S92 A93 R94 Y95 R162 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4p5b D 2.27 BS05 FAD D 1 R86 H87 R88 H188 L192 R193 H204 R82 H83 R84 H184 L188 R189 H200 2.1.1.148 C1IC19 RIELRSDITVELVDSSASDLAVVKAARVSTAGEDANDELYDGGSTRGLIRYLMRSRHGSPFEHNSMTFLVRAPIFTVRHLMRHRTWSFNEESARYREVGAAFYVPDATRLLRQEGKPGDYRYVGGSTDDHQQVVRSATRAYEVAFEEYQRLLDSGIAREIARLVLPVSTYSVLYATCNARALMHFLSLRTHRPDAAYVSHPQREIEMVAEQMETAWAKLMPVTHEAFTAFGRVSP 4rij A 2.12 BS01 GDP A 1 A272 C273 G274 K275 T276 N277 R420 W501 F502 F510 G514 F515 N518 A261 C262 G263 K264 T265 N266 R409 W490 F491 F499 G503 F504 N507 4.1.1.32 I6Y334 APTNHQGLLSWVEEVAELTQPDRVVFTDGSEEEFQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNWMDPGEMRSIMKDLYRGCMRGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMTRMGKAALEKMGDDGFFVKALHSVGAPLEPGQKDVAWPCSETKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKTNLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMRTIAAGNTVFTNVALTDDGDVWWEGLEGDPQHLIDWKGNDWYFRETETNAAHPNSRYCTPMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQHGVFIGATLGSEQTAAAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADESKLPKVFFVNWFRRGDDGRFLWPGFGENSRVLKWIVDRIEHKAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALAVDADEWRQELPLIEEWLQFVGEKLPTGVKDEFDALKERLG 4rij A 2.12 BS02 ZN A 1 K229 H249 D296 K218 H238 D285 4.1.1.32 I6Y334 APTNHQGLLSWVEEVAELTQPDRVVFTDGSEEEFQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNWMDPGEMRSIMKDLYRGCMRGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMTRMGKAALEKMGDDGFFVKALHSVGAPLEPGQKDVAWPCSETKYITHFPETREIWSYGSGYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKTNLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMRTIAAGNTVFTNVALTDDGDVWWEGLEGDPQHLIDWKGNDWYFRETETNAAHPNSRYCTPMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQHGVFIGATLGSEQTAAAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADESKLPKVFFVNWFRRGDDGRFLWPGFGENSRVLKWIVDRIEHKAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALAVDADEWRQELPLIEEWLQFVGEKLPTGVKDEFDALKERLG 4rlh A 2.26 BS01 0WE A 1 F94 A95 R97 I100 Y146 N155 Y156 M159 F203 F94 A95 R97 I100 Y146 N155 Y156 M159 F198 1.3.1.9 Q63SW7 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPISGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAVVGGM 4rlh B 2.26 BS01 0WE B 1 F94 A95 I100 Y146 N155 Y156 M159 P191 I200 F203 I206 F94 A95 I100 Y146 N155 Y156 M159 P191 I200 F203 I206 1.3.1.9 Q63SW7 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAVVGGM 4rlh D 2.26 BS01 0WE D 1 F94 A95 R97 I100 Y146 N155 Y156 M159 K163 F203 F94 A95 R97 I100 Y146 N155 Y156 M159 K163 F198 1.3.1.9 Q63SW7 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPISGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAVVGGM 4rlh C 2.26 BS01 0WE C 1 F94 A95 R97 I100 Y146 N155 Y156 M159 K163 A196 I200 F94 A95 R97 I100 Y146 N155 Y156 M159 K163 A196 I200 1.3.1.9 Q63SW7 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSGFNAVVGGM 4rpu A 2.27 BS01 ZN A 1 H104 H108 E205 H73 H77 E174 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSRPVRPHTVEKPVPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rpu A 2.27 BS02 3UE A 1 G382 Y383 I432 Q435 F443 M446 Y450 L467 G351 Y352 I401 Q404 F412 M415 Y419 L436 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSRPVRPHTVEKPVPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rpu A 2.27 BS03 3UE A 2 I337 T340 A343 F344 S347 L348 S351 Y380 G382 L428 K431 I432 Y450 E463 L464 L467 Q470 I306 T309 A312 F313 S316 L317 S320 Y349 G351 L397 K400 I401 Y419 E432 L433 L436 Q439 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSRPVRPHTVEKPVPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rpu B 2.27 BS01 ZN B 1 H104 H108 E205 H73 H77 E174 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rpu B 2.27 BS02 3UE B 1 L60 G382 Y383 I432 Q435 M446 Y450 L467 L29 G347 Y348 I397 Q400 M411 Y415 L432 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rpu B 2.27 BS03 3UE B 2 I337 T340 A343 F344 S347 L348 Y380 L428 K431 Y450 E463 L464 L467 Q470 I302 T305 A308 F309 S312 L313 Y345 L393 K396 Y415 E428 L429 L432 Q435 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rpu B 2.27 BS04 CA B 1 L629 E634 L594 E599 3.4.24.- Q5JRX3 AACERALQYKLGDKIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILQHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFSKQTTVSVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIVEKDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVEDFLRSIGRSPVRTVEKPVIRKLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIAKDPSWIIR 4rv6 A 3.19 BS01 RPB A 1 Q759 E763 H862 G863 Y889 Y896 F897 A898 S904 Y907 E988 Q98 E102 H199 G200 Y226 Y233 F234 A235 S241 Y244 E325 2.4.2.30 P09874 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4rv6 B 3.19 BS01 RPB B 1 Q759 E763 H862 G863 T887 G888 Y889 Y896 F897 A898 K903 S904 Y907 Q98 E102 H201 G202 T226 G227 Y228 Y235 F236 A237 K242 S243 Y246 2.4.2.30 P09874 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 4ryv A 1.38 BS01 ZEA A 1 N7 Q9 Y19 L22 T23 Y80 Y82 S101 I103 G113 I115 G138 L139 F142 N7 Q9 Y19 L22 T23 Y80 Y82 S101 I103 G113 I115 G138 L139 F142 P52778 GIFAFENEQSSTVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKLDAIDEANLTYNYSIIGGEGLDESLEKISYESKILPGPDGGSIGKINVKFHTKGDVLSETVRDQAKFKGLGLFKAIEGYVLAHPDY 4ryv A 1.38 BS02 ZEA A 2 F5 N7 V117 F119 R131 D132 K135 F5 N7 V117 F119 R131 D132 K135 P52778 GIFAFENEQSSTVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKLDAIDEANLTYNYSIIGGEGLDESLEKISYESKILPGPDGGSIGKINVKFHTKGDVLSETVRDQAKFKGLGLFKAIEGYVLAHPDY 4ryv A 1.38 BS03 ZEA A 3 S26 D27 V30 K53 I55 H68 I84 Y99 G138 L141 S26 D27 V30 K53 I55 H68 I84 Y99 G138 L141 P52778 GIFAFENEQSSTVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKLDAIDEANLTYNYSIIGGEGLDESLEKISYESKILPGPDGGSIGKINVKFHTKGDVLSETVRDQAKFKGLGLFKAIEGYVLAHPDY 4ryv A 1.38 BS04 ZEA A 4 H62 T63 E88 H62 T63 E88 P52778 GIFAFENEQSSTVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKLDAIDEANLTYNYSIIGGEGLDESLEKISYESKILPGPDGGSIGKINVKFHTKGDVLSETVRDQAKFKGLGLFKAIEGYVLAHPDY 4ryv A 1.38 BS05 ZEA A 5 V33 I34 G140 K143 A144 V33 I34 G140 K143 A144 P52778 GIFAFENEQSSTVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKLDAIDEANLTYNYSIIGGEGLDESLEKISYESKILPGPDGGSIGKINVKFHTKGDVLSETVRDQAKFKGLGLFKAIEGYVLAHPDY 4txw A 1.40 BS01 CA A 1 K15 D18 D20 T23 N147 E148 K18 D21 D23 T26 N150 E151 3.2.1.35 VYEPSLVDAYVGDDGAKKAVDGDLKTRVKFLGAPSTGDTIVYDLGQEILVDNLKYVVLDTEVDHVRDGKIQLSLDGETWTDAINIGDGVENGVDDMFSTPLKNGYKHGNQSGGIVPIDSAYVEGDNLNQKARYVRILFTAPYRHRWTVINELMINNGEY 4txw A 1.40 BS02 CA A 2 D64 D84 V86 N88 D67 D87 V89 N91 3.2.1.35 VYEPSLVDAYVGDDGAKKAVDGDLKTRVKFLGAPSTGDTIVYDLGQEILVDNLKYVVLDTEVDHVRDGKIQLSLDGETWTDAINIGDGVENGVDDMFSTPLKNGYKHGNQSGGIVPIDSAYVEGDNLNQKARYVRILFTAPYRHRWTVINELMINNGEY 4uwq A 3.28 BS01 MN A 1 D47 H49 D143 H297 H299 D22 H24 D118 H272 H274 Q72IT0 EDPRSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq A 3.28 BS02 MN A 2 D47 D143 H174 H274 H297 D22 D118 H149 H249 H272 Q72IT0 EDPRSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq D 3.28 BS01 MN D 1 D47 H49 D143 H274 H297 H299 D19 H21 D115 H246 H269 H271 Q72IT0 RSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq D 3.28 BS02 MN D 2 D47 D143 H174 H274 H297 D19 D115 H146 H246 H269 Q72IT0 RSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq G 3.28 BS01 MN G 1 D47 H49 D143 H299 D22 H24 D118 H274 Q72IT0 EDPRSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq G 3.28 BS02 MN G 2 D47 D143 H174 H274 H297 D22 D118 H149 H249 H272 Q72IT0 EDPRSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq H 3.28 BS01 III I 1 L103 A104 L61 A62 Q72IS6 EGEDLEHLEQALKEVFGKGFKDLTPSDAVKLNMPAIAESGANVPAEVEHLFADKNPTPHILAPYYATRVRLAETTAIRAVVETQDGKLLLASASTRVTVGGCG 4uwq H 3.28 BS02 III I 2 Y113 Y114 A115 T116 R117 Y64 Y65 A66 T67 R68 Q72IS6 EGEDLEHLEQALKEVFGKGFKDLTPSDAVKLNMPAIAESGANVPAEVEHLFADKNPTPHILAPYYATRVRLAETTAIRAVVETQDGKLLLASASTRVTVGGCG 4uwq J 3.28 BS01 MN J 1 D47 H49 D143 H297 H299 D21 H23 D117 H271 H273 Q72IT0 DPRSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4uwq J 3.28 BS02 MN J 2 D47 D143 H174 H274 H297 D21 D117 H148 H248 H271 Q72IT0 DPRSLYDLPPYGDATLLYFSDLHGQAFPHYFMEPPNLIAPKPLMGRPGYLTGEAILRYYGVERGTPLAYLLSYVDFVELARTFGPIGGMGALTALIRDQKARVEAEGGKALVLDGGDTWTNSGLSLLTRGEAVVRWQNLVGVDHMVSHCEWTLGRERVEELLGLFRGEFLSYNIVDDLFGDPLFPAYRIHRVGPYALAVVGASYPYVKVSHPESFTEGLSFALDERRLQEAVDKARAEGANAVVLLSHNGMQLDAALAERIRGIDLILSGHTHDLTPRPWRVGKTWIVAGSAAGKALMRVDLKLWKGGIANLRVRVLPVLAEHLPKAEDVEAFLKAQLAPHQDHLFTPLAVSETLLYKRDTLYSTWDQLVGEAVKAIYPEVEVVFSPAVRWGTTILPGQAITWDHLYAYTGFTYPELYLFYLRGAQIKAVLEDIASNVFTSDPFYQQGGDVSRVFGLRYVLDPDAPTGERVREVEVGGRPLDPNRRYLAAAYGGRLQRVGEAKPGYEPRPIYEVLAEYLRSVGRVRVRPEPNVKVIGRNYRLPEVTG 4v2o B 2.13 BS01 CLQ B 1 A58 M65 E69 L73 A61 M68 E72 L76 P07602 26616259 GASGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQPKEICALVGFCD 4v2o C 2.13 BS01 CLQ C 1 M61 M65 E69 L73 M64 M68 E72 L76 P07602 26616259 GASGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQPKEICALVGFCD 4wu3 A 2.20 BS01 4IP A 1 K296 K297 Y305 K250 K251 Y259 3.1.3.8 A3QMF6 PAVVKNPPKLALKIDRADVNQLPRNFRMGSDKYVGVTKTGIMPTRKGMDTMNVSASSCFSEKELEAILKKVPVKPSQFYDVDLRGESHGYLNGTAVSWFANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKDAWLHYHSYAGMGRTTIFMVMHDILKNAKDVSFDDIIQRQKLIGIVDLSEIPDKKKNYGRKAYIERYQFVQHFYDYVKENPDLKTPYSVWAKKNKVNSWEPDYNGYIWRLDTKDRNQLPRNFRTMNSAFRTDVNVKKTGKGFTPTPTRKGLDTLYMSGSAEFSNGELQAMLPVLKQQAKGPIYIMDLRQETHGVFNGNAVSWYGLRDWGNLGKNKAEVLKDENSRLNAARGKSLIVAELDKDKMPIDPKPVKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANAWLHFHSQAGAGRTTAYMAMYDMMKNPDVSLGDILSRQYLLGGNYVAYEIAKPKPDQWKADYYHQKAHMIEKFYQYVQENHADGFKTSWSQWLAA 4wu3 A 2.20 BS02 4IP A 2 R351 D449 K485 D519 H520 S548 Q549 A550 G551 A552 G553 R554 K600 Y604 R305 D403 K439 D473 H474 S502 Q503 A504 G505 A506 G507 R508 K554 Y558 3.1.3.8 A3QMF6 PAVVKNPPKLALKIDRADVNQLPRNFRMGSDKYVGVTKTGIMPTRKGMDTMNVSASSCFSEKELEAILKKVPVKPSQFYDVDLRGESHGYLNGTAVSWFANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKDAWLHYHSYAGMGRTTIFMVMHDILKNAKDVSFDDIIQRQKLIGIVDLSEIPDKKKNYGRKAYIERYQFVQHFYDYVKENPDLKTPYSVWAKKNKVNSWEPDYNGYIWRLDTKDRNQLPRNFRTMNSAFRTDVNVKKTGKGFTPTPTRKGLDTLYMSGSAEFSNGELQAMLPVLKQQAKGPIYIMDLRQETHGVFNGNAVSWYGLRDWGNLGKNKAEVLKDENSRLNAARGKSLIVAELDKDKMPIDPKPVKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANAWLHFHSQAGAGRTTAYMAMYDMMKNPDVSLGDILSRQYLLGGNYVAYEIAKPKPDQWKADYYHQKAHMIEKFYQYVQENHADGFKTSWSQWLAA 4wu3 B 2.20 BS01 4IP B 1 K296 K297 Y305 K250 K251 Y259 3.1.3.8 A3QMF6 PAVVKNPPKLALKIDRADVNQLPRNFRMGSDKYVGVTKTGIMPTRKGMDTMNVSASSCFSEKELEAILKKVPVKPSQFYDVDLRGESHGYLNGTAVSWFANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKDAWLHYHSYAGMGRTTIFMVMHDILKNAKDVSFDDIIQRQKLIGIVDLSEIPDKKKNYGRKAYIERYQFVQHFYDYVKENPDLKTPYSVWAKKNKVNSWEPDYNGYIWRLDTKDRNQLPRNFRTMNSAFRTDVNVKKTGKGFTPTPTRKGLDTLYMSGSAEFSNGELQAMLPVLKQQAKGPIYIMDLRQETHGVFNGNAVSWYGLRDWGNLGKNKAEVLKDENSRLNAARGKSLIVAELDKDKMPIDPKPVKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANAWLHFHSQAGAGRTTAYMAMYDMMKNPDVSLGDILSRQYLLGGNYVAYEIAKPKPDQWKADYYHQKAHMIEKFYQYVQENHADGFKTSWSQWLAA 4wu3 C 2.20 BS01 4IP C 1 K296 K297 Y305 K250 K251 Y259 3.1.3.8 A3QMF6 PAVVKNPPKLALKIDRADVNQLPRNFRMGSDKYVGVTKTGIMPTRKGMDTMNVSASSCFSEKELEAILKKVPVKPSQFYDVDLRGESHGYLNGTAVSWFANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKDAWLHYHSYAGMGRTTIFMVMHDILKNAKDVSFDDIIQRQKLIGIVDLSEIPDKKKNYGRKAYIERYQFVQHFYDYVKENPDLKTPYSVWAKKNKVNSWEPDYNGYIWRLDTKDRNQLPRNFRTMNSAFRTDVNVKKTGKGFTPTPTRKGLDTLYMSGSAEFSNGELQAMLPVLKQQAKGPIYIMDLRQETHGVFNGNAVSWYGLRDWGNLGKNKAEVLKDENSRLNAARGKSLIVAELDKDKMPIDPKPVKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANAWLHFHSQAGAGRTTAYMAMYDMMKNPDVSLGDILSRQYLLGGNYVAYEIAKPKPDQWKADYYHQKAHMIEKFYQYVQENHADGFKTSWSQWLAA 4wu3 C 2.20 BS02 4IP C 2 R351 D449 K485 D519 H520 S548 Q549 A550 G551 A552 G553 R554 K600 Y604 R305 D403 K439 D473 H474 S502 Q503 A504 G505 A506 G507 R508 K554 Y558 3.1.3.8 A3QMF6 PAVVKNPPKLALKIDRADVNQLPRNFRMGSDKYVGVTKTGIMPTRKGMDTMNVSASSCFSEKELEAILKKVPVKPSQFYDVDLRGESHGYLNGTAVSWFANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKDAWLHYHSYAGMGRTTIFMVMHDILKNAKDVSFDDIIQRQKLIGIVDLSEIPDKKKNYGRKAYIERYQFVQHFYDYVKENPDLKTPYSVWAKKNKVNSWEPDYNGYIWRLDTKDRNQLPRNFRTMNSAFRTDVNVKKTGKGFTPTPTRKGLDTLYMSGSAEFSNGELQAMLPVLKQQAKGPIYIMDLRQETHGVFNGNAVSWYGLRDWGNLGKNKAEVLKDENSRLNAARGKSLIVAELDKDKMPIDPKPVKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANAWLHFHSQAGAGRTTAYMAMYDMMKNPDVSLGDILSRQYLLGGNYVAYEIAKPKPDQWKADYYHQKAHMIEKFYQYVQENHADGFKTSWSQWLAA 4wu3 D 2.20 BS01 4IP D 1 K296 K297 Y305 K250 K251 Y259 3.1.3.8 A3QMF6 PAVVKNPPKLALKIDRADVNQLPRNFRMGSDKYVGVTKTGIMPTRKGMDTMNVSASSCFSEKELEAILKKVPVKPSQFYDVDLRGESHGYLNGTAVSWFANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKDAWLHYHSYAGMGRTTIFMVMHDILKNAKDVSFDDIIQRQKLIGIVDLSEIPDKKKNYGRKAYIERYQFVQHFYDYVKENPDLKTPYSVWAKKNKVNSWEPDYNGYIWRLDTKDRNQLPRNFRTMNSAFRTDVNVKKTGKGFTPTPTRKGLDTLYMSGSAEFSNGELQAMLPVLKQQAKGPIYIMDLRQETHGVFNGNAVSWYGLRDWGNLGKNKAEVLKDENSRLNAARGKSLIVAELDKDKMPIDPKPVKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTMPANAWLHFHSQAGAGRTTAYMAMYDMMKNPDVSLGDILSRQYLLGGNYVAYEIAKPKPDQWKADYYHQKAHMIEKFYQYVQENHADGFKTSWSQWLAA 4wzf A 1.70 BS01 CA A 1 E61 S112 D289 E8 S59 D232 O07242 26469317 GGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVFGSH 4wzf B 1.70 BS01 CA B 1 E61 S112 D289 E8 S59 D232 O07242 26469317 GGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVFGSHH 4x4k A 2.30 BS01 CU A 1 H426 C489 I491 H494 H408 C471 I473 H476 H8ZRU2 26625287 YSIDTNWYDVTPTGVTREYWLSVENSTITPDGYTRSAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVTQCPIAPGDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFLQDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTKYRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAADNYWIRGNWGTTCSTNNEAANATGILRYDSSSIANPTSVGTTPRGTCEDEPVASLVPHLALDVGGYSLVDEQVSSAFTNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYNVVALEQEEWVVYVIEDLTGFGIWHPIHLHGHDFFIVAQETDVFNSDESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQSSIAVKMTDTAIFEDTCANWNAYTPTQLFAEDDSGI 4x4k A 2.30 BS02 CU A 2 H133 H429 H431 H488 H119 H411 H413 H470 H8ZRU2 26625287 YSIDTNWYDVTPTGVTREYWLSVENSTITPDGYTRSAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVTQCPIAPGDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFLQDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTKYRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAADNYWIRGNWGTTCSTNNEAANATGILRYDSSSIANPTSVGTTPRGTCEDEPVASLVPHLALDVGGYSLVDEQVSSAFTNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYNVVALEQEEWVVYVIEDLTGFGIWHPIHLHGHDFFIVAQETDVFNSDESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQSSIAVKMTDTAIFEDTCANWNAYTPTQLFAEDDSGI 4x4k A 2.30 BS03 CU A 3 H89 W129 H131 H490 H75 W115 H117 H472 H8ZRU2 26625287 YSIDTNWYDVTPTGVTREYWLSVENSTITPDGYTRSAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVTQCPIAPGDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFLQDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTKYRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAADNYWIRGNWGTTCSTNNEAANATGILRYDSSSIANPTSVGTTPRGTCEDEPVASLVPHLALDVGGYSLVDEQVSSAFTNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYNVVALEQEEWVVYVIEDLTGFGIWHPIHLHGHDFFIVAQETDVFNSDESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQSSIAVKMTDTAIFEDTCANWNAYTPTQLFAEDDSGI 4x4k A 2.30 BS04 CU A 4 H87 H429 H431 H73 H411 H413 H8ZRU2 26625287 YSIDTNWYDVTPTGVTREYWLSVENSTITPDGYTRSAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVTQCPIAPGDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFLQDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTKYRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAADNYWIRGNWGTTCSTNNEAANATGILRYDSSSIANPTSVGTTPRGTCEDEPVASLVPHLALDVGGYSLVDEQVSSAFTNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYNVVALEQEEWVVYVIEDLTGFGIWHPIHLHGHDFFIVAQETDVFNSDESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQSSIAVKMTDTAIFEDTCANWNAYTPTQLFAEDDSGI 4x4k A 2.30 BS05 CU A 5 E80 H81 E66 H67 H8ZRU2 26625287 YSIDTNWYDVTPTGVTREYWLSVENSTITPDGYTRSAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVTQCPIAPGDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFLQDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTKYRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAADNYWIRGNWGTTCSTNNEAANATGILRYDSSSIANPTSVGTTPRGTCEDEPVASLVPHLALDVGGYSLVDEQVSSAFTNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYNVVALEQEEWVVYVIEDLTGFGIWHPIHLHGHDFFIVAQETDVFNSDESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQSSIAVKMTDTAIFEDTCANWNAYTPTQLFAEDDSGI 4xc0 A 1.77 BS01 ACP A 1 E36 N40 A44 D82 M87 N95 L96 G122 G125 V126 G127 F128 T174 E35 N39 A43 D81 M86 N94 L95 G121 G124 V125 G126 F127 T173 P54651 26599366 AESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIK 4xcj A 1.75 BS01 ADP A 1 N40 A44 D82 M87 N95 L96 G125 V126 G127 F128 T174 N40 A44 D82 M87 N95 L96 G125 V126 G127 F128 T174 P54651 26599366 MAESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKE 4xcl A 1.21 BS01 AGS A 1 N40 A44 D82 M87 N95 L96 V126 G127 F128 T174 N40 A44 D82 M87 N95 L96 V126 G127 F128 T174 P54651 26599366 MAESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIK 4xd8 A 1.55 BS01 ANP A 1 N40 A44 D82 M87 N95 L96 V126 G127 F128 T174 N40 A44 D82 M87 N95 L96 V126 G127 F128 T174 P54651 26599366 MAESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEK 4xdm A 1.50 BS01 GDM A 1 N40 A41 D43 A44 K47 D82 I85 M87 N95 L96 R101 G125 V126 G127 F128 T174 I176 N40 A41 D43 A44 K47 D82 I85 M87 N95 L96 R101 G125 V126 G127 F128 T174 I176 P54651 26599366 MAESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKE 4xka A 2.00 BS01 GOL A 1 N40 L96 F128 I176 N36 L92 F124 I172 P54651 26599366 QVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKEVD 4xka A 2.00 BS02 GOL A 2 A44 K47 I85 G86 M87 T174 A40 K43 I81 G82 M83 T170 P54651 26599366 QVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKEVD 4xrx A 3.20 BS01 NDP A 1 K72 T75 T77 R82 L288 H309 G310 T311 V312 T313 R314 H315 T327 N328 D375 K70 T73 T75 R80 L265 H286 G287 T288 V289 T290 R291 H292 T304 N305 D352 1.1.1.42 O75874 26280302 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 4xrx A 3.20 BS02 42V A 1 T77 S94 N96 G97 R100 N101 T75 S92 N94 G95 R98 N99 1.1.1.42 O75874 26280302 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 4xrx B 3.20 BS01 NDP B 1 K72 T75 T77 R82 N96 L288 G289 E306 H309 G310 T311 V312 T313 R314 H315 T327 N328 D375 K70 T73 T75 R80 N94 L262 G263 E280 H283 G284 T285 V286 T287 R288 H289 T301 N302 D349 1.1.1.42 O75874 26280302 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGHHATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 4xt2 A BS01 43L A 1 F244 S246 H248 M252 A277 F280 Y281 M289 S292 H293 L296 V302 V303 S304 Y307 M309 L319 T321 G323 I337 C339 N341 F11 S13 H15 M19 A44 F47 Y48 M56 S59 H60 L63 V69 V70 S71 Y74 M76 L86 T88 G90 I104 C106 N108 Q99814 26226049 GEFKGLDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEK 4xt2 C BS01 43L C 1 F244 S246 H248 M252 F254 A277 F280 Y281 M289 S292 H293 L296 V302 V303 S304 Y307 M309 L319 T321 G323 I337 C339 N341 F9 S11 H13 M17 F19 A42 F45 Y46 M54 S57 H58 L61 V67 V68 S69 Y72 M74 L84 T86 G88 I102 C104 N106 Q99814 26226049 FKGLDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEK 4xtq A 1.64 BS01 BL8 A 1 M168 Y197 T201 V202 P203 A206 Y210 R216 R248 M250 S251 C253 H254 Y257 A268 V282 H284 M156 Y185 T189 V190 P191 A194 Y198 R204 R236 M238 S239 C241 H242 Y245 A256 V270 H272 RSMVAGHASGEEIHLAGSIQPHGALLVVSEHDHRVIQASANAAEFLNLGSVLGVPLAEIDGDLLIKILPHLDPTAEGMPVAVRCRIGNPSTEYCGLMHRPPEGGLIIELERAGPSIDLSGTLAPALERIRTAGSLRALCDDTVLLFQQCTGYDRVMVYRFDEQGHGLVFSECHVPGLESYFGNRYPSSTVPQMARQLYVRQRVRVLVDVTYQPVPLEPRLSPLTGRDLDMSGCFLRSMSPCHLQYLKDMGVRATLAVSLVVGGKLWGLVVCHHYLPRFIRFELRAICKRLAERIATRITALES 4xzu A 2.61 BS01 MG A 1 V130 C131 T134 T135 V129 C130 T131 T132 26598467 IQLVQSGPELKKPGKTVKISCKASDYTFTDYSLHWVKQAPGKGLKWMGWINTETGDPAYADDFKGRFAFSLETSVRTAYLQINNLKNEDTAIYFCAREDDGLASWGQGTTLTVSSAKTTAPSVYPLAPVCTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPR 4xzu M 2.61 BS01 MG M 1 Y2195 Q2222 Y22 Q49 P00451 26598467 CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 4xzu F 2.61 BS01 MG F 1 S120 S121 E122 S120 S121 E122 26598467 QIVLTQSPAIMSASPGEKVTMTCSASSTVSYMYWYQQKPGSSPRFLISDTSNLASGVPVRFSGSGSGTSYSLTISRIEAEDAATYYCQHWSSYPLTFGGGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYETCEATHIVKSFNRNE 4y6m A 2.27 BS01 48Q A 1 I32 D34 G36 S37 V78 F111 T114 S118 I123 Y192 D214 G216 T217 S218 T221 I290 L292 F294 I300 I32 D34 G36 S37 V78 F111 T114 S118 I123 Y192 D214 G216 T217 S218 T221 I290 L292 F294 I300 3.4.23.39 P46925 26625296 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4y6m B 2.27 BS01 48Q B 1 M15 I32 D34 G36 V78 S79 F111 I123 Y192 D214 G216 T217 S218 L292 I300 M14 I31 D33 G35 V77 S78 F110 I122 Y191 D213 G215 T216 S217 L291 I299 3.4.23.39 P46925 26625296 SNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4y6m C 2.27 BS01 48Q C 1 M15 I32 D34 G36 S37 F111 T114 Y192 D214 G216 T217 S218 I300 M15 I32 D34 G36 S37 F111 T114 Y192 D214 G216 T217 S218 I300 3.4.23.39 P46925 26625296 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4ya8 A 3.30 BS01 49W A 1 I32 D34 G36 Y77 V78 S79 F111 T114 I123 Y192 D214 G216 T217 S218 I290 L292 I300 I32 D34 G36 Y77 V78 S79 F111 T114 I123 Y192 D214 G216 T217 S218 I290 L292 I300 3.4.23.39 P46925 26625296 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4ya8 B 3.30 BS01 49W B 1 M15 I32 D34 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 L292 I300 M15 I32 D34 Y77 V78 S79 F111 I123 Y192 D214 G216 T217 S218 L292 I300 3.4.23.39 P46925 26625296 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4ya8 C 3.30 BS01 49W C 1 I32 D34 G36 Y77 V78 S79 F111 T114 I123 Y192 D214 G216 T217 S218 I290 L292 I300 I32 D34 G36 Y77 V78 S79 F111 T114 I123 Y192 D214 G216 T217 S218 I290 L292 I300 3.4.23.39 P46925 26625296 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4ya8 D 3.30 BS01 49W D 1 M15 I32 D34 G36 Y77 V78 S79 F111 T114 S118 I123 Y192 D214 G216 T217 S218 I290 I300 M14 I31 D33 G35 Y76 V77 S78 F110 T113 S117 I122 Y191 D213 G215 T216 S217 I289 I299 3.4.23.39 P46925 26625296 SNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPLTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAKKNL 4yo2 A 3.07 BS01 NUC C 1 R113 K116 S117 L118 E153 R156 R313 Y316 N320 V333 R4 K7 S8 L9 E44 R47 R158 Y161 N165 V178 A0AVK6 QPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKP 4yo2 A 3.07 BS02 NUC D 1 S112 R113 K114 R154 R155 Y158 N162 R172 K175 N176 K264 L266 R267 K307 T310 R313 R314 S3 R4 K5 R45 R46 Y49 N53 R63 K66 N67 K109 L111 R112 K152 T155 R158 R159 A0AVK6 QPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKP 4zm6 A 2.80 BS01 ACO A 1 R520 I560 F561 L615 L616 M617 V618 Q623 G624 K625 G626 G628 T629 G650 S667 A670 F673 K676 R506 I546 F547 L601 L602 M603 V604 Q609 G610 K611 G612 G614 T615 G636 S653 A656 F659 K662 3.2.1.52,2.3.1.3 V9M3A9 NLDKEIGQLLMCGFDGLEPTPGIIDLIENHNLGSIILFSRNIATPKQVQKLTHSLQQIARNAGHKRPLFIAVDQENGVVRRLGDSGTYLPGNMALGALGSSTAARNVAMAISKELLTLGMNWNLAPVLDVNNNPLNPVIGVRSYGQDPELVARMGLAQVEGYQRGKVATSIKHFPGHGDTATDSHLDVPVINKTLEELDKTELVPFKKALEAGGIACPTSVMVGHMLLPHFNKDVVSSIAPEIVRDLLRRRFGYKGVIITDCLEMDAVKETVGTPKGALMALQAGNDMAMISHTLAFQKDAFKVLYSALQEGQLDKDEIRQSLQRVAQLKDQFLNWDDVLQQADLKTMGSEAHATLSKELYDRVPTVVTNRKNTLPIRPAQTDKILFLAAHVPEKEPFNSFHASLLKRHTNLEYIIYNEETPDLSQKIQEADWVIIGTANANLYPFQVRMVQQAQKLAKRLVVAAVMNPYDQMCFPQVDTYLVTYEYTPPAHEAAVRLIFGEIETRSRLPISIPNVDDAIAPATFIVDDYRNDDDLDHVTAMWDDIFGKDWPLRKDKINLGLQRAKLQKHKVARDSQGKIVGFVATQIVVVDNKKHGQLMLLMVSPSYQGKGVGTLLHDAALEHFREQGADCIKLGSTYPRFFPGVPDDDAQSRKAQAFFSKKGWRMDDNLVHDLIGDLQDYKVPDKIQARMLKEKIWFGRIKPSETWELYAFQQRNFPHWLSTYQHHVELGDYQDLIVARQDDENGRVIASLILNTTHVSHEYRSDLIWTDDKLFGERSGGMACVGVAQEERGRGIGIGIVAHANWLLKQRGVTKSYVDWVELLDFYSRVGYKTWRSYRLGHF 4zm6 B 2.80 BS01 ACO B 1 R520 I560 F561 L613 M614 L615 L616 V618 Q623 G624 K625 G626 G628 T629 G650 P661 A670 F673 K676 R506 I546 F547 L599 M600 L601 L602 V604 Q609 G610 K611 G612 G614 T615 G636 P647 A656 F659 K662 3.2.1.52,2.3.1.3 V9M3A9 NLDKEIGQLLMCGFDGLEPTPGIIDLIENHNLGSIILFSRNIATPKQVQKLTHSLQQIARNAGHKRPLFIAVDQENGVVRRLGDSGTYLPGNMALGALGSSTAARNVAMAISKELLTLGMNWNLAPVLDVNNNPLNPVIGVRSYGQDPELVARMGLAQVEGYQRGKVATSIKHFPGHGDTATDSHLDVPVINKTLEELDKTELVPFKKALEAGGIACPTSVMVGHMLLPHFNKDVVSSIAPEIVRDLLRRRFGYKGVIITDCLEMDAVKETVGTPKGALMALQAGNDMAMISHTLAFQKDAFKVLYSALQEGQLDKDEIRQSLQRVAQLKDQFLNWDDVLQQADLKTMGSEAHATLSKELYDRVPTVVTNRKNTLPIRPAQTDKILFLAAHVPEKEPFNSFHASLLKRHTNLEYIIYNEETPDLSQKIQEADWVIIGTANANLYPFQVRMVQQAQKLAKRLVVAAVMNPYDQMCFPQVDTYLVTYEYTPPAHEAAVRLIFGEIETRSRLPISIPNVDDAIAPATFIVDDYRNDDDLDHVTAMWDDIFGKDWPLRKDKINLGLQRAKLQKHKVARDSQGKIVGFVATQIVVVDNKKHGQLMLLMVSPSYQGKGVGTLLHDAALEHFREQGADCIKLGSTYPRFFPGVPDDDAQSRKAQAFFSKKGWRMDDNLVHDLIGDLQDYKVPDKIQARMLKEKIWFGRIKPSETWELYAFQQRNFPHWLSTYQHHVELGDYQDLIVARQDDENGRVIASLILNTTHVSHEYRSDLIWTDDKLFGERSGGMACVGVAQEERGRGIGIGIVAHANWLLKQRGVTKSYVDWVELLDFYSRVGYKTWRSYRLGHF 4ztx A 2.10 BS01 ZN A 1 H652 C654 E676 C737 H651 C653 E675 C736 2.1.1.14 Q8X1E4 VQSSVLGFPRMGVLRDLKKANEAYWADKISQEALLAEGKRLRLAHWKIQKDAGVDIIPSNDFAHYDHVLDHIQLFNAVPERYTSQKLSPLDEYFAMGRGHQKGGVDVPALEMVKWFDSNYHYVKPTLQDNQTFSLAKDPKPVREFLEAKEAGFQTRPVLVGPVSFLALGKADRGSSVDPITLLDKLVPVYVELLKQLKAAGAESVQIDEPVLVFDLRPEVKAAFKPAYEAIAAAGDAVPKVVVATYFGDIVHNFDVLPAFSGAAGLHVDLVRNPEQLEPVLKQLGPNQILSAGVVDGRNIWKNDFAKSLEILQTAVKALGSERVIVATSSSLIHTPHTLASEKKLPSDVYEWFSFAVEKVKEVATLAKAVTEPEAVKAELEANAAAIKARTDSKRTNDPAVKERQAQVTPEQHNRKAPFNTRYAEQKKHLSLPLFPTTTIGSFPQTSEIRVQRNKFTKGEISAEEYERFIEKEIELAVKIQDELDLDVYVHGEPERNDMVQYFGERLNGYVFTTHAWVQSYGSRCVRPPIIVGDISRPAPMTVKESKYAASISKKPMKGMLTGPVTCLRWSFPRVDVHQSVQCQQLALALRDEVVDLEKNGIYVIQVDEPALREGLPLRKGQEREAYLKWAVDSFKLATAGVENSTQIHSHFCYSEFQDFFHAIAALDADVLSIENSKSDAKLLKVFIDEEYPRHIGPGVYDIHSPRVPTLEEFKQRIEEMLAYLKPEQLWINPDCGLKTRKWDEVKGALSHMVEAAKYFREKYANKA 5a24 A 1.50 BS01 E64 A 1 Q20 G24 C25 C26 W27 G68 G69 D164 H165 Q19 G23 C24 C25 W26 G67 G68 D163 H164 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNGNDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPANNEQALQQAAATQPISVAIDASDPSFQSYSSGIYSGPCNTNLDHAVTVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPTA 5a88 A 2.08 BS01 ADP A 1 V193 R195 G196 A197 G198 G201 K202 P207 T208 A209 N210 S269 V271 R274 D275 A276 L278 Y279 V9 R11 G12 A13 G14 G17 K18 P23 T24 A25 N26 S79 V81 R84 D85 A86 L88 Y89 2.7.1.26,2.7.7.2 Q59263 RHFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAE 5a88 A 2.08 BS02 CA A 1 T208 N210 T24 N26 2.7.1.26,2.7.7.2 Q59263 RHFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAE 5a88 B 2.08 BS01 ADP B 1 V193 G196 A197 G198 P207 T208 A209 N210 S269 V271 R274 D275 A276 L278 Y279 V8 G11 A12 G13 P17 T18 A19 N20 S72 V74 R77 D78 A79 L81 Y82 2.7.1.26,2.7.7.2 Q59263 HFYVTGPVVRGAGLGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFSVEQLLEVMAKDVQKTRTLLAQDVQAETYFLQA 5a88 B 2.08 BS02 CA B 1 T208 N210 E268 T18 N20 E71 2.7.1.26,2.7.7.2 Q59263 HFYVTGPVVRGAGLGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFSVEQLLEVMAKDVQKTRTLLAQDVQAETYFLQA 5a88 C 2.08 BS01 ADP C 1 V193 R195 G196 G198 G201 K202 P207 T208 A209 N210 S269 V271 R274 D275 A276 L278 Y279 V8 R10 G11 G13 G16 K17 P22 T23 A24 N25 S78 V80 R83 D84 A85 L87 Y88 2.7.1.26,2.7.7.2 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVTYFLQAE 5a88 C 2.08 BS02 CA C 1 T208 N210 T23 N25 2.7.1.26,2.7.7.2 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVTYFLQAE 5a88 D 2.08 BS01 ADP D 1 V193 R195 G196 P207 T208 A209 N210 S269 V271 R274 D275 A276 L278 Y279 V8 R10 G11 P14 T15 A16 N17 S70 V72 R75 D76 A77 L79 Y80 2.7.1.26,2.7.7.2 Q59263 HFYVTGPVVRGGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQA 5a88 D 2.08 BS02 CA D 1 T208 N210 T15 N17 2.7.1.26,2.7.7.2 Q59263 HFYVTGPVVRGGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQA 5a89 A 1.65 BS01 FMN A 1 G196 A197 G198 R199 G200 T208 N210 V224 A251 S253 N257 P258 T259 F260 E268 R292 M294 E295 F297 L303 M307 D310 G11 A12 G13 R14 G15 T23 N25 V39 A66 S68 N72 P73 T74 F75 E83 R107 M109 E110 F112 L118 M122 D125 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQA 5a89 A 1.65 BS02 MG A 1 T208 N210 T23 N25 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQA 5a89 A 1.65 BS03 ZN A 1 H186 D321 H325 H1 D136 H140 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQA 5a89 A 1.65 BS04 ADP A 1 V193 R195 G196 A197 G198 G200 G201 P207 T208 A209 N210 S269 V271 R274 D275 A276 D277 L278 Y279 V8 R10 G11 A12 G13 G15 G16 P22 T23 A24 N25 S84 V86 R89 D90 A91 D92 L93 Y94 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQA 5a89 B 1.65 BS01 FMN B 1 G196 A197 G198 R199 G200 L204 T208 N210 V224 A251 S253 N257 P258 T259 F260 E268 R292 M294 E295 F297 L303 M307 D310 G11 A12 G13 R14 G15 L19 T23 N25 V39 A66 S68 N72 P73 T74 F75 E83 R107 M109 E110 F112 L118 M122 D125 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a89 B 1.65 BS02 ADP B 1 V193 R195 G196 A197 G198 G200 G201 P207 T208 A209 N210 S269 V271 R274 D275 A276 D277 L278 Y279 V8 R10 G11 A12 G13 G15 G16 P22 T23 A24 N25 S84 V86 R89 D90 A91 D92 L93 Y94 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a89 B 1.65 BS03 MG B 1 T208 N210 T23 N25 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a89 B 1.65 BS04 ZN B 1 H186 D321 H325 H1 D136 H140 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a8a A 1.80 BS01 FMN A 1 G196 A197 G198 R199 G200 L204 T208 N210 V224 A251 S253 N257 P258 T259 F260 E268 R292 M294 E295 F297 L303 M307 D310 G13 A14 G15 R16 G17 L21 T25 N27 V41 A68 S70 N74 P75 T76 F77 E85 R109 M111 E112 F114 L120 M124 D127 2.7.1.26 Q59263 GRHFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a8a A 1.80 BS02 ADP A 1 V193 R195 G196 A197 G198 G200 G201 P207 T208 A209 N210 S269 V271 R274 D275 A276 L278 Y279 V10 R12 G13 A14 G15 G17 G18 P24 T25 A26 N27 S86 V88 R91 D92 A93 L95 Y96 2.7.1.26 Q59263 GRHFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a8a A 1.80 BS03 MG A 1 T208 N210 T25 N27 2.7.1.26 Q59263 GRHFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a8a A 1.80 BS04 ZN A 1 H186 D321 H325 H3 D138 H142 2.7.1.26 Q59263 GRHFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAES 5a8a B 1.80 BS01 FMN B 1 G196 A197 G198 R199 G200 L204 T208 N210 V224 A251 S253 N257 P258 T259 F260 E268 R292 M294 E295 F297 L303 M307 D310 G11 A12 G13 R14 G15 L19 T23 N25 V39 A66 S68 N72 P73 T74 F75 E83 R107 M109 E110 F112 L118 M122 D125 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAE 5a8a B 1.80 BS02 ADP B 1 V193 R195 G196 A197 G198 G200 G201 P207 T208 A209 N210 S269 V271 R274 D275 A276 L278 Y279 V8 R10 G11 A12 G13 G15 G16 P22 T23 A24 N25 S84 V86 R89 D90 A91 L93 Y94 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAE 5a8a B 1.80 BS03 MG B 1 T208 N210 T23 N25 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAE 5a8a B 1.80 BS04 ZN B 1 H186 D321 H325 H1 D136 H140 2.7.1.26 Q59263 HFYVTGPVVRGAGRGGKELGFPTANQYFHDTVALPADGVYAGWLTILPTEAPVSGNMEPEVAYAAAISVGTNPTFGDEQRSVESFVLDRDADLYGHDVKVEFVDHVRAMEKFDSVEQLLEVMAKDVQKTRTLLAQDVQAHKMAPETYFLQAE 5aa7 A 1.55 BS01 CU1 A 1 H32 H109 F164 H1 H78 F133 3.2.1.14 C7R4I0 HGWVTDPPSRQALCASGETSFDCGQISYEPQSVEAPKGATTCSGGNEAFAILDDNSKPWPTTEIASTVDLTWKLTAPHNTSTWEYFVDGQLHQTFDQKGQQPPTSLTHTLTDLPTGEHTILARWNVSNTNNAFYNCMDVVVS 5aa7 B 1.55 BS01 CU1 B 1 H32 H109 F164 H1 H78 F133 3.2.1.14 C7R4I0 HGWVTDPPSRQALCASGETSFDCGQISYEPQSVEAPKGATTCSGGNEAFAILDDNSKPWPTTEIASTVDLTWKLTAPHNTSTWEYFVDGQLHQTFDQKGQQPPTSLTHTLTDLPTGEHTILARWNVSNTNNAFYNCMDVVVS 5amm A 2.09 BS01 HEM A 1 P60 S61 R64 W67 P162 D163 G164 F175 L188 I189 A191 H192 G195 E196 C197 H198 F201 S202 Y204 W208 L250 S252 F284 P27 S28 R31 W34 P129 D130 G131 F142 L155 I156 A158 H159 G162 E163 C164 H165 F168 S169 Y171 W175 L217 S219 F251 1.11.1.11,1.11.1.5 Q4Q3K2 26598276 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHNKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5amm A 2.09 BS02 CA A 1 E69 S72 G80 S81 P82 S86 E92 E36 S39 G47 S48 P49 S53 E59 1.11.1.11,1.11.1.5 Q4Q3K2 26598276 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHNKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5amm B 2.09 BS01 HEM B 1 P60 S61 I63 R64 W67 P162 G164 V171 L188 I189 A191 H192 G195 E196 C197 H198 F201 S202 Y204 W208 L250 S252 F284 P27 S28 I30 R31 W34 P129 G131 V138 L155 I156 A158 H159 G162 E163 C164 H165 F168 S169 Y171 W175 L217 S219 F251 1.11.1.11,1.11.1.5 Q4Q3K2 26598276 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHNKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5amm B 2.09 BS02 CA B 1 E69 S72 G80 S81 P82 S86 E92 E36 S39 G47 S48 P49 S53 E59 1.11.1.11,1.11.1.5 Q4Q3K2 26598276 SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHNKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPA 5aob A 1.79 BS01 BUA A 1 G53 G54 S126 A127 H248 G49 G50 S122 A123 H244 3.1.1.1 RLRYPPEMPGAEVKVYKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQCEYFAGRGMVAMAADYRVGSRHNVKVADCVADAKSAIRWVRQHAAELGVDPQKIVASGGSAGGHLAACTVMVPDLEAPEEDHTISSQANAAILFNPVLILSREGLKDHVPRQDWEERLRERLGTEPKAVSPYHHIRAGLPPMIIFHGTADNTVPFETIRLFAEAMKKAGNRCELVPFEGAAHGFFNFGRGDNLAYQKTLELADEFLVEIGFLAPKG 5aoc A 1.79 BS01 LEA A 1 G53 G54 S126 A127 H248 G53 G54 S126 A127 H243 3.1.1.1 AEVGRLRYPPEMPGAEVKVYKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQCEYFAGRGMVAMAADYRVGSRHNVKVADCVADAKSAIRWVRQHAAELGVDPQKIVASGGSAGGHLAACTVMVPDLEAPEEDHTISSQANAAILFNPVLILSREGLRQDWEERLRERLGTEPKAVSPYHHIRAGLPPMIIFHGTADNTVPFETIRLFAEAMKKAGNRCELVPFEGAAHGFFNFGRGDNLAYQKTLELADEFLVEIGFLAPKG 5boe A 1.60 BS01 PEP A 1 G40 A41 S42 D244 D318 K343 H371 R372 S373 K394 G40 A41 S42 D244 D318 K343 H371 R372 S373 K394 4.2.1.11 O69174 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLD 5boe A 1.60 BS02 MG A 1 D244 E291 D318 D244 E291 D318 4.2.1.11 O69174 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLD 5boe B 1.60 BS01 PEP B 1 D244 D318 K343 H371 R372 S373 K394 D244 D318 K343 H371 R372 S373 K394 4.2.1.11 O69174 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLD 5boe B 1.60 BS02 MG B 1 D244 E291 D318 D244 E291 D318 4.2.1.11 O69174 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLD 5bof A 2.45 BS01 MG A 1 D244 E291 D318 D244 E291 D318 4.2.1.11 O69174 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK 5bof B 2.45 BS01 MG B 1 D244 E291 D318 K394 D242 E289 D316 K392 4.2.1.11 O69174 MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK 5bwa A 3.20 BS01 PLP A 1 A67 K69 D88 A111 H197 G237 E274 G276 R277 Y389 A41 K43 D62 A85 H165 G205 E235 G237 R238 Y332 4.1.1.17 P11926 26443277 TAKDILDQKINDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDKFEEITGVINPALDKYFPSRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVATFNGFQRPTIYYVMS 5c3u A 1.76 BS01 PLP A 1 K52 N80 S147 P178 G180 G181 G182 G183 L184 S234 L235 S281 T312 K37 N65 S132 P163 G165 G166 G167 G168 L169 S219 L220 S266 T297 4.3.1.17 26367174 QSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQTRGTNIQFVCGSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSHLILYGENWTAAEVHARKLVRRNGIYVPSSDHALIWQGHSTIVQELKTQLNDNPPAAIICPVGGGGLLNGVIMGLQEADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLISKAVSSKSLELSLNHPVVPFAVSDAMAADAVRLFAEDFKMLVEASAGAALSLCYTHLIRDILPSLSPAKDVVVLVTGGSDISLAHLDEYRKKYM 5c4n D 1.63 BS01 NAP D 1 G8 S30 Y31 A32 R46 G48 G49 F50 G51 G52 H73 F75 A76 A77 Q78 M79 N82 I134 Q137 K196 G8 S30 Y31 A32 R40 G42 G43 F44 G45 G46 H67 F69 A70 A71 Q72 M73 N76 I128 Q131 K190 1.3.1.54 O68098 MTRLLVLGGTTEASRLAKTLADQGFEAVFSYAGAQPLPTRIGGFGGVAGLVDYLTREGVSHVIDATHPFAAQMSANAVAACAQTGVALCAFERAPWTAQAGDRWTHVPDLAAAVAALPQAPARVFLAIGKQHLRDFSAAPQHHYLLRLVDPPEGPLPLPDARAVIARGPFTVQGDTELLRSETITHVVAKNAGGAGAEAKLIAARSLGLPVILIDRPAVPARDICATLEGVMGWLADHGATPRG 5ced A 2.02 BS01 PNM A 1 A69 S70 Q250 N292 T342 K357 T358 G359 S360 K365 A32 S33 Q193 N235 T285 K300 T301 G302 S303 K308 3.4.16.4 Q6MHT0 MVYLNSMCHMAANSKTQQIQGDDNKDDKFPLASISKVVTTLWAVDRLGPDYRFKTKLHVTPTANGSYDIHIEGSRDPLFGRNMSYFLISELNRMKITKIEKLTFDENFLLAWQASIVRATLTSSFATAISPGYYTILKTKAARIGVQMSNRPKIDVRTISFVKKAEFQKNEKSTTMVLMSAPLKTILKRMNNQSNNYIADNLYWNLGGTEAFNAYIAGKMQADTSDIEFHNGSGNNEGSVAKPVYNEATCEMMIKVLYSLDKSLSAKGYDLSDVMAVAAKDKASTVGSYGGVMAGSTTAKTGSVNKAKTLMGSVSTKNGEIYFAVLMHTDYDKSRSDWGVASQQIKNKVSQLINQNGGPKAIKYTEQLPLPFDKYSYLTKA 5cg1 A 2.07 BS01 NAD A 1 G13 A15 S19 I20 Q40 L44 C63 D64 V65 S91 I92 L144 S145 Y146 K163 A189 G190 P191 I192 G12 A14 S18 I19 Q39 L43 C62 D63 V64 S90 I91 L143 S144 Y145 K162 A188 G189 P190 I191 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg1 A 2.07 BS02 BBN A 1 G93 Y146 Y156 M159 K163 G92 Y145 Y155 M158 K162 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg1 B 2.07 BS01 NAD B 1 G13 A15 S19 I20 Q40 C63 D64 V65 S91 I92 L144 S145 Y146 K163 A189 G190 P191 I192 T194 G12 A14 S18 I19 Q39 C62 D63 V64 S90 I91 L143 S144 Y145 K162 A188 G189 P190 I191 T193 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg1 B 2.07 BS02 BBN B 1 G93 Y146 Y156 M159 K163 G92 Y145 Y155 M158 K162 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg2 A 2.11 BS01 NAD A 1 G13 A15 S19 I20 Q40 L44 C63 D64 V65 S91 I92 I119 L144 S145 Y146 K163 A189 G190 P191 I192 G12 A14 S18 I19 Q39 L43 C62 D63 V64 S90 I91 I118 L143 S144 Y145 K162 A188 G189 P190 I191 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIREAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg2 A 2.11 BS02 CJ3 A 1 G93 F94 Y146 Y156 M159 K163 G92 F93 Y145 Y155 M158 K162 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIREAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg2 B 2.11 BS01 NAD B 1 G13 A15 S19 I20 Q40 C63 D64 V65 S91 I92 L144 S145 Y146 K163 A189 G190 P191 I192 G12 A14 S18 I19 Q39 C62 D63 V64 S90 I91 L143 S144 Y145 K162 A188 G189 P190 I191 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPICEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cg2 B 2.11 BS02 CJ3 B 1 G93 F94 Y146 Y156 M159 K163 G92 F93 Y145 Y155 M158 K162 1.3.1.9 P0AEK4 26625295 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPICEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 5cgm A 1.95 BS01 MAL A 1 K283 N287 S298 W300 A301 Q343 Y376 D378 R411 D413 N414 E442 D498 K552 Y553 K260 N264 S275 W277 A278 Q320 Y349 D351 R384 D386 N387 E415 D471 K525 Y526 2.4.99.16 G7CL00 26616850 GSVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPPGPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLQGESELNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAEKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cgm A 1.95 BS02 PO4 A 1 G96 H97 T98 H103 R694 E696 G76 H77 T78 H83 R667 E669 2.4.99.16 G7CL00 26616850 GSVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPPGPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLQGESELNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAEKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cgm A 1.95 BS03 PO4 A 2 T445 R446 R449 T418 R419 R422 2.4.99.16 G7CL00 26616850 GSVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPPGPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLQGESELNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAEKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cgm B 1.95 BS01 MAL B 1 K283 N287 S298 W300 A301 Q343 Y376 D378 I379 R411 D413 N414 E442 D498 K552 Y553 K254 N258 S269 W271 A272 Q314 Y347 D349 I350 R382 D384 N385 E413 D469 K523 Y524 2.4.99.16 G7CL00 26616850 GSVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPKPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLLNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAENPPKKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cgm B 1.95 BS02 PO4 B 1 G96 H97 T98 H103 R694 E696 G75 H76 T77 H82 R665 E667 2.4.99.16 G7CL00 26616850 GSVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPKPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLLNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAENPPKKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cgm B 1.95 BS03 PO4 B 2 T445 R446 R449 T416 R417 R420 2.4.99.16 G7CL00 26616850 GSVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPKPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLLNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAENPPKKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cim B 3.32 BS01 MAL B 1 K283 N287 S298 W300 Q343 Y376 D378 I379 R411 D413 N414 E442 D498 K552 Y553 K262 N266 S277 W279 Q322 Y355 D357 I358 R390 D392 N393 E421 D477 K531 Y532 2.4.99.16 G7CL00 26616850 SVAGRIVIDDVQPVVSNGRYPAKAVVGEVVPVAATVWREGHDAVAATLVVRYHGTTYPDLADPPPGVPGAVKPQRLPMSPGHTPDVFHGHFTPDRVGLWTYRVDGWGDPIASWRHNVTAKLSELNNDLLVGARLLERAATGVPRELREALLEAAAALRAPGDPFTRAGAALSAEVSDLLAEYPLREFVTRGEQYGVWVDRPEARFSSWYEMFPRSTGGWDAEGRPVHGTFATAAEALPRIARMGFDVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPQLGTIEDFDEFVASARDLGLEVALDLALQCAPDHPWAREHPEWFTVLPDGSIAYAENPPKKYQDIYPLNFDNDPAGIYQEVLRVVRFWISHGVNIFRVDNPHTKPPNFWAWLIGQIKNENPDVLFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTSKWELTEFGQEIAAKADIARPNLFVNTPDILHESLQHGGPGMFAIRAVLAATMGPAWGVYSGYELFENQPVRPGSEEYLNSEKYELRPRDFESALARGESLEPFLTRLNEIRRLHPALRELRTIRFHHVDNDALLAYSKFDPGTGDTVLVVVTLNPFGAEEATLWLDMPELGMEPYDRFWVRDEITGEEYQWGQANYVRLDPAKAVAHVLNMPLIPADKRLQLLRRE 5cxk A 1.90 BS01 ZN A 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk A 1.90 BS02 BCT A 1 W39 V47 A49 R64 C96 Y181 W39 V47 A49 R64 C96 Y181 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk B 1.90 BS01 ZN B 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk B 1.90 BS02 BCT B 1 W39 G41 V47 A49 L52 R64 Y181 W39 G41 V47 A49 L52 R64 Y181 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk H 1.90 BS01 ZN H 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk H 1.90 BS02 BCT H 1 W39 G41 V47 P48 A49 L52 R64 Y181 W39 G41 V47 P48 A49 L52 R64 Y181 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk G 1.90 BS01 ZN G 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk G 1.90 BS02 BCT G 1 W39 G41 V47 P48 A49 R64 Y181 W39 G41 V47 P48 A49 R64 Y181 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk D 1.90 BS01 ZN D 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk D 1.90 BS02 BCT D 1 W39 V47 A49 L52 R64 Y181 W39 V47 A49 L52 R64 Y181 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk C 1.90 BS01 ZN C 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk C 1.90 BS02 BCT C 1 W39 G41 V47 A49 R64 Y181 W39 G41 V47 A49 R64 Y181 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk F 1.90 BS01 ZN F 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5cxk E 1.90 BS01 ZN E 1 C42 D44 H98 C101 C42 D44 H98 C101 4.2.1.1 A0A086SLX8 MPEIKQLFENNSKWSASIKAETPEYFAKLAKGQNPDFLWIGCADSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLQVKHIIVCGHYGCGGVTAAIDNPQLGLINNWLLHIRDYYLKHREYLDKMPAEDRSDKLAEINVAEQVYNLANSTVLQNAWERGQAVEVHGFVYGIEDGRLEYLGVRCASRSAVEDNYHKALEKILNPNHRLLCR 5d0i A 1.90 BS01 ZN A 1 C312 H314 C331 C334 C35 H37 C54 C57 Q6ZSG1 NTIERFTFPHKYKDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIE 5d0i A 1.90 BS02 ZN A 2 C294 C297 H317 C320 C17 C20 H40 C43 Q6ZSG1 NTIERFTFPHKYKDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIE 5d0i B 1.90 BS01 ZN B 1 C312 H314 C331 C334 C19 H21 C38 C41 Q6ZSG1 EKCTICLSMLEEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGA 5d0i B 1.90 BS02 ZN B 2 C294 C297 H317 C320 C3 C6 H24 C27 Q6ZSG1 EKCTICLSMLEEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGA 5d0k C 2.65 BS01 ZN C 1 C312 H314 C331 C334 C39 H41 C58 C61 Q6ZSG1 VQNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k C 2.65 BS02 ZN C 2 C294 C297 H317 C320 C21 C24 H44 C47 Q6ZSG1 VQNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k F 2.65 BS01 ZN F 1 C312 H314 C331 C334 C38 H40 C57 C60 Q6ZSG1 QNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k F 2.65 BS02 ZN F 2 C294 C297 H317 C320 C20 C23 H43 C46 Q6ZSG1 QNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k I 2.65 BS01 ZN I 1 C312 H314 C331 C334 C38 H40 C57 C60 Q6ZSG1 QNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k I 2.65 BS02 ZN I 2 C294 C297 H317 C320 C20 C23 H43 C46 Q6ZSG1 QNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k L 2.65 BS01 ZN L 1 C312 H314 C331 C334 C38 H40 C57 C60 Q6ZSG1 QNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0k L 2.65 BS02 ZN L 2 C294 C297 H317 C320 C20 C23 H43 C46 Q6ZSG1 QNTIERFTFPHKYKKTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL 5d0m C 1.91 BS01 ZN C 1 C312 H314 C331 C334 C33 H35 C52 C55 Q6ZSG1 QNTIERFTFPHKYKEKCTICLSMLGEDVRRLPCAHLFHQLCVDQWLAMSKKCPICRVDIE 5d0m C 1.91 BS02 ZN C 2 C294 C297 H317 C320 C17 C20 H38 C41 Q6ZSG1 QNTIERFTFPHKYKEKCTICLSMLGEDVRRLPCAHLFHQLCVDQWLAMSKKCPICRVDIE 5d3k A 1.70 BS01 CA A 1 D49 D52 D35 D38 2.3.1.94 Q03133 26592346 SSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGSDGFSLDLVDMADGPGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEPLPSSMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPPGHQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAGEPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQEHADAIARHIDAWLGGGNS 5d3k A 1.70 BS02 CA A 2 E108 D199 T201 E94 D185 T187 2.3.1.94 Q03133 26592346 SSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGSDGFSLDLVDMADGPGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEPLPSSMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPPGHQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAGEPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQEHADAIARHIDAWLGGGNS 5d3z A 2.10 BS01 57H A 1 S142 A143 M179 H259 S128 A129 M163 H243 2.3.1.94 Q03133 26592346 SSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGSDGFSLDLVDMADGPGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEPLPSSMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPPQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAGEPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQEHADAIARHIDAWLG 5d6o C 1.80 BS01 MG C 1 D73 H74 D73 H74 2.3.1.-,2.3.1.31 Q8NS43 MLDNSFYTAEVQGPYETASIGRLELEEGGVIEDCWLAYATAGTLNEDKSNAILIPTWYSGTHQTWFQQYIGTDHALDPSKYFIISINQIGNGLSVSPANTADDSISMSKFPNVRIGDDVVAQDRLLRQEFGITELFAVVGGSMGAQQTYEWIVRFPDQVHRAAPIAGTAKNTPHDFIFTQTLNETVEADPGFNGGEYSSHEEVADGLRRQSHLWAAMGFSTEFWKQEAWRRLGLESKESVLADFLDPLFMSMDPNTLLNNAWKWQHGDVSRHTGGDLAAALGRVKAKTFVMPISEDMFFPVRDCAAEQALIPGSELRVIEDIAGHLGLFNVSENYIPQIDKNLKELFES 5d6o D 1.80 BS01 MG D 1 V11 Q63 V11 Q63 2.3.1.-,2.3.1.31 Q8NS43 MLDNSFYTAEVQGPYETASIGRLELEEGGVIEDCWLAYATAGTLNEDKSNAILIPTWYSGTHQTWFQQYIGTDHALDPSKYFIISINQIGNGLSVSPANTADDSISMSKFPNVRIGDDVVAQDRLLRQEFGITELFAVVGGSMGAQQTYEWIVRFPDQVHRAAPIAGTAKNTPHDFIFTQTLNETVEADPGFNGGEYSSHEEVADGLRRQSHLWAAMGFSTEFWKQEAWRRLGLESKESVLADFLDPLFMSMDPNTLLNNAWKWQHGDVSRHTGGDLAAALGRVKAKTFVMPISEDMFFPVRDCAAEQALIPGSELRVIEDIAGHLGLFNVSENYIPQIDKNLKELFES 5d8g A 1.89 BS01 MG A 1 Q119 E293 Q113 E287 4.1.99.1 P0A853 KHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAMTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV 5d8g A 1.89 BS02 MG A 2 D53 R334 H358 T421 I422 D49 R328 H352 T415 I416 4.1.99.1 P0A853 KHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAMTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV 5d8g A 1.89 BS03 CA A 1 A66 R69 E316 A319 V320 A62 R65 E310 A313 V314 4.1.99.1 P0A853 KHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAMTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV 5dfa A 2.50 BS01 ZN A 1 C124 C164 C166 C169 C122 C162 C164 C167 3.2.1.23 F8TRX0 PKYERTYTTQANFILHGGDYNPDQWLDRPDILQADLELMKLSHTNTFTVGVFAWSALEPEEGVYRFEWLDKVFDDIYRIGGRVILATPSGARPAWLSQKYPEVLRVNAARVRQLHGGRHNHCFTSSVYREKTQHINRLLAERYGDHPALLMWHVSNEYGGECHCNLCQEAFREWLKKKYNHDLDALNAAWWTSFWSHTYTDWSQIESPSPIGEHTIHGLNLDWKRFVTDQTISFFENEIVPLRELTPHIPITTNFMADTHDLIPFQGLDYSKFAKHLDVISWDAYPAWHNDWESTADLAMKVGFINDLYRSLKQQPFLLMACTPSLVNWHKVNKAKRPGMHFLSSMQMIAHGSDSILYFQWRKSRGSFEKFHGAVVDHDNRTDSRVFQEVAEVGKALKKMSGIVGTNRPAEVAILYDWENNWALNDAQGFAAETKRYPQTLVQHYRPFWERDIPVDVITKEHDFSRYKLLIAPMLYLVSEETIARLKEFVANGGTLVMTYISGIVDEHDLAYLGGWHQDLREMFGMEPIETDTLYPRDRNSVHYRGRSYELKDYATVIKIHAATVEGVYEDDFYADTPAVTSNQYGKGQAYYIGGRLEDQFHRDFYQELMEKLDLRPVLFVKHEKGVSVQARQAPECDYVFIMNFTEEKQAVVLEEKVKDLFTGEEIVGEIMLDKYEVRVVEKRR 5dfa B 2.50 BS01 ZN B 1 C124 C164 C166 C169 C121 C161 C163 C166 3.2.1.23 F8TRX0 KYERTYTTQANFILHGGDYNPDQWLDRPDILQADLELMKLSHTNTFTVGVFAWSALEPEEGVYRFEWLDKVFDDIYRIGGRVILATPSGARPAWLSQKYPEVLRVNAARVRQLHGGRHNHCFTSSVYREKTQHINRLLAERYGDHPALLMWHVSNEYGGECHCNLCQEAFREWLKKKYNHDLDALNAAWWTSFWSHTYTDWSQIESPSPIGEHTIHGLNLDWKRFVTDQTISFFENEIVPLRELTPHIPITTNFMADTHDLIPFQGLDYSKFAKHLDVISWDAYPAWHNDWESTADLAMKVGFINDLYRSLKQQPFLLMACTPSLVNWHKVNKAKRPGMHFLSSMQMIAHGSDSILYFQWRKSRGSFEKFHGAVVDHDNRTDSRVFQEVAEVGKALKKMSGIVGTNRPAEVAILYDWENNWALNDAQGFAAETKRYPQTLVQHYRPFWERDIPVDVITKEHDFSRYKLLIAPMLYLVSEETIARLKEFVANGGTLVMTYISGIVDEHDLAYLGGWHQDLREMFGMEPIETDTLYPRDRNSVHYRGRSYELKDYATVIKIHAATVEGVYEDDFYADTPAVTSNQYGKGQAYYIGGRLEDQFHRDFYQELMEKLDLRPVLFVKHEKGVSVQARQAPECDYVFIMNFTEEKQAVVLEEKVKDLFTGEEIVGEIMLDKYEVRVVEKRR 5dfa C 2.50 BS01 ZN C 1 C124 C164 C166 C169 C122 C162 C164 C167 3.2.1.23 F8TRX0 PKYERTYTTQANFILHGGDYNPDQWLDRPDILQADLELMKLSHTNTFTVGVFAWSALEPEEGVYRFEWLDKVFDDIYRIGGRVILATPSGARPAWLSQKYPEVLRVNAARVRQLHGGRHNHCFTSSVYREKTQHINRLLAERYGDHPALLMWHVSNEYGGECHCNLCQEAFREWLKKKYNHDLDALNAAWWTSFWSHTYTDWSQIESPSPIGEHTIHGLNLDWKRFVTDQTISFFENEIVPLRELTPHIPITTNFMADTHDLIPFQGLDYSKFAKHLDVISWDAYPAWHNDWESTADLAMKVGFINDLYRSLKQQPFLLMACTPSLVNWHKVNKAKRPGMHFLSSMQMIAHGSDSILYFQWRKSRGSFEKFHGAVVDHDNRTDSRVFQEVAEVGKALKKMSGIVGTNRPAEVAILYDWENNWALNDAQGFAAETKRYPQTLVQHYRPFWERDIPVDVITKEHDFSRYKLLIAPMLYLVSEETIARLKEFVANGGTLVMTYISGIVDEHDLAYLGGWHQDLREMFGMEPIETDTLYPRDRNSVHYRGRSYELKDYATVIKIHAATVEGVYEDDFYADTPAVTSNQYGKGQAYYIGGRLEDQFHRDFYQELMEKLDLRPVLFVKHEKGVSVQARQAPECDYVFIMNFTEEKQAVVLEEKVKDLFTGEEIVGEIMLDKYEVRVVEKRR 5dgr A 1.90 BS01 GCS A 1 D143 Y147 H150 W219 W446 Q448 N524 W551 E555 W557 D138 Y142 H145 W214 W441 Q443 N519 W546 E550 W552 Q6LUT2 26621872 MQLLTNHLGYERLGAKQAILQAQHHADIICCQSGQSIMQLPLQACGPVAQWHIGDTYSIDFTALNICGDYRIRVGDTESASFCVAEGLLMQNTFSDVLHYFKSQRCSGIYECADKKVPLFGTNETVDVHGGWYDASGDVSKYFSHLSYGNYLNPQQTPMVVWNMLTAYEVLEDEESIADFTRVRLVEEALYGADFLLRMQHPQGYFYMTVFDKWSKSTEQREVCAFSTQDGHKSADYQAGFRQGAGVAIAALAAASRLSNLASTSRIPQCGDIKADTYLEAAKKGYWHLKEMNHQYLDNGKENIIDEYCALLASVELYRSTQENNFLAEARMWADKLMARQMSDHNFAHYWAANDDGSRPYFHAAEAGLPAIALMQYLQIETHAQRAEQCQSVLLNALNFELSITHEVNNPFGYPRQYTKAVNGDKQSAFFMPHDNETGYWWQGENARIASLITMAYMAQNTINDNEIKSQLMIYAHRLTDWILGLNPFDMCMLDGHGRNNPDYLPELGFSNAKGGVCNGITSGFENEQGIAFKPEKQKDDMLQNWRWGEQWIPHGAWYLLAITMQFKERNHV 5dgr B 1.90 BS01 GCS B 1 D143 Y147 H150 W219 W446 Q448 N524 W551 E555 W557 D138 Y142 H145 W214 W439 Q441 N517 W544 E548 W550 Q6LUT2 26621872 MQLLTNHLGYERLGAKQAILQAQHHADIICCQSGQSIMQLPLQACGPVAQWHIGDTYSIDFTALNICGDYRIRVGDTESASFCVAEGLLMQNTFSDVLHYFKSQRCSGIYECADKKVPLFGTNETVDVHGGWYDASGDVSKYFSHLSYGNYLNPQQTPMVVWNMLTAYEVLEDEESIADFTRVRLVEEALYGADFLLRMQHPQGYFYMTVFDKWSKSTEQREVCAFSTQDGHKSADYQAGFRQGAGVAIAALAAASRLSNLASTSRIPQCGKADTYLEAAKKGYWHLKEMNHQYLDNGKENIIDEYCALLASVELYRSTQENNFLAEARMWADKLMARQMSDHNFAHYWAANDDGSRPYFHAAEAGLPAIALMQYLQIETHAQRAEQCQSVLLNALNFELSITHEVNNPFGYPRQYTKAVNGDKQSAFFMPHDNETGYWWQGENARIASLITMAYMAQNTINDNEIKSQLMIYAHRLTDWILGLNPFDMCMLDGHGRNNPDYLPELGFSNAKGGVCNGITSGFENEQGIAFKPEKQKDDMLQNWRWGEQWIPHGAWYLLAITMQFKERNHV 5dou A 2.60 BS01 MG A 1 E714 N716 E672 N674 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou A 2.60 BS02 MG A 2 Q700 E714 Q658 E672 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou A 2.60 BS03 PO4 A 1 L592 G593 H659 Q700 E714 N716 R718 R721 L550 G551 H617 Q658 E672 N674 R676 R679 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou A 2.60 BS04 ADP A 1 R547 M585 R587 A591 L592 G593 G594 E623 K624 S625 V626 T627 E631 M656 G657 V658 H659 Q700 I713 E714 S790 R505 M543 R545 A549 L550 G551 G552 E581 K582 S583 V584 T585 E589 M614 G615 V616 H617 Q658 I671 E672 S748 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou A 2.60 BS05 ADP A 2 A1104 L1127 M1139 K1168 F1169 V1170 E1175 A1199 G1200 V1201 H1202 S1203 Q1243 L1245 I1254 E1255 A1062 L1085 M1088 K1101 F1102 V1103 E1108 A1132 G1133 V1134 H1135 S1136 Q1176 L1178 I1187 E1188 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou A 2.60 BS06 NLG A 1 I1366 Q1367 T1391 A1393 T1394 W1410 L1438 P1439 T1443 K1444 F1445 N1449 I1299 Q1300 T1324 A1326 T1327 W1343 L1371 P1372 T1376 K1377 F1378 N1382 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou A 2.60 BS07 MG A 3 Q1243 E1255 Q1176 E1188 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou B 2.60 BS01 MG B 1 A591 L592 E714 N716 A542 L543 E665 N667 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou B 2.60 BS02 MG B 2 H659 Q700 E714 H610 Q651 E665 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou B 2.60 BS03 PO4 B 1 L592 G593 H659 Q700 E714 N716 R718 R721 L543 G544 H610 Q651 E665 N667 R669 R672 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou B 2.60 BS04 ADP B 1 R547 M585 R587 L592 G593 G594 E623 K624 S625 V626 T627 E631 M656 G657 V658 H659 T660 Q700 I713 E714 S790 R498 M536 R538 L543 G544 G545 E574 K575 S576 V577 T578 E582 M607 G608 V609 H610 T611 Q651 I664 E665 S741 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou B 2.60 BS05 ADP B 2 A1104 L1127 M1139 K1168 F1169 V1170 E1175 A1199 G1200 V1201 H1202 S1203 Q1243 L1245 I1254 E1255 A1055 L1078 M1083 K1106 F1107 V1108 E1113 A1137 G1138 V1139 H1140 S1141 Q1181 L1183 I1192 E1193 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou B 2.60 BS06 NLG B 1 I1366 Q1367 T1391 A1393 T1394 W1410 L1438 T1443 K1444 F1445 N1449 I1304 Q1305 T1329 A1331 T1332 W1348 L1376 T1381 K1382 F1383 N1387 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou B 2.60 BS07 MG B 3 Q1243 E1255 Q1181 E1193 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLSRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDEMKKFLEEAHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSKSLFHYRQ 5dou C 2.60 BS01 MG C 1 A591 E714 N716 R718 A546 E669 N671 R673 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou C 2.60 BS02 MG C 2 H659 Q700 E714 H614 Q655 E669 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou C 2.60 BS03 PO4 C 1 L592 G593 H659 Q700 E714 N716 R718 R721 L547 G548 H614 Q655 E669 N671 R673 R676 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou C 2.60 BS04 ADP C 1 R547 M585 R587 A591 L592 G593 G594 E623 K624 S625 V626 T627 E631 M656 G657 V658 H659 T660 Q700 I713 E714 S790 R502 M540 R542 A546 L547 G548 G549 E578 K579 S580 V581 T582 E586 M611 G612 V613 H614 T615 Q655 I668 E669 S745 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou C 2.60 BS05 ADP C 2 L1127 R1129 K1168 F1169 V1170 E1175 A1199 G1200 V1201 H1202 S1203 Q1243 L1245 E1255 L1082 R1084 K1100 F1101 V1102 E1107 A1131 G1132 V1133 H1134 S1135 Q1175 L1177 E1187 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou C 2.60 BS06 NLG C 1 I1366 Q1367 T1391 A1393 T1394 W1410 L1438 T1443 K1444 F1445 N1449 I1298 Q1299 T1323 A1325 T1326 W1342 L1370 T1375 K1376 F1377 N1381 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou C 2.60 BS07 MG C 3 Q1243 E1255 Q1175 E1187 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPAMNVVFSEDPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS01 MG D 1 E714 N716 E672 N674 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS02 MG D 2 Q700 E714 Q658 E672 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS03 PO4 D 1 L592 G593 H659 Q700 E714 N716 R718 R721 L550 G551 H617 Q658 E672 N674 R676 R679 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS04 ADP D 1 R547 M585 R587 A591 L592 G593 G594 E623 K624 S625 V626 T627 E631 M656 G657 V658 H659 Q700 I713 E714 S790 R505 M543 R545 A549 L550 G551 G552 E581 K582 S583 V584 T585 E589 M614 G615 V616 H617 Q658 I671 E672 S748 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS05 ADP D 2 L1127 R1129 K1168 F1169 V1170 E1175 A1199 G1200 V1201 H1202 S1203 Q1243 L1245 I1254 E1255 L1085 R1087 K1109 F1110 V1111 E1116 A1140 G1141 V1142 H1143 S1144 Q1184 L1186 I1195 E1196 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS06 NLG D 1 I1366 Q1367 T1391 A1393 T1394 W1410 L1438 P1439 T1443 K1444 F1445 N1449 I1307 Q1308 T1332 A1334 T1335 W1351 L1379 P1380 T1384 K1385 F1386 N1390 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dou D 2.60 BS07 MG D 3 Q1243 E1255 Q1184 E1196 6.3.4.16 P31327 26592762 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRMNVVFSEDEMKKFLEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKDSKSLFHYRQ 5dw8 A 2.40 BS01 CA A 1 E65 D83 I85 E56 D74 I76 3.1.3.25 A0A0C5I0W4 MALYGFAQGLIQEAGIRIKQLMEQNNDLVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPHHDALIQLHEQR 5dw8 A 2.40 BS02 2AM A 1 I85 D86 G87 T88 G182 A184 R203 D208 I76 D77 G78 T79 G173 A175 R194 D199 3.1.3.25 A0A0C5I0W4 MALYGFAQGLIQEAGIRIKQLMEQNNDLVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPHHDALIQLHEQR 5dw8 A 2.40 BS03 CA A 2 D83 D86 W207 D208 D74 D77 W198 D199 3.1.3.25 A0A0C5I0W4 MALYGFAQGLIQEAGIRIKQLMEQNNDLVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPHHDALIQLHEQR 5dw8 B 2.40 BS01 CA B 1 D83 D86 D208 D72 D75 D197 3.1.3.25 A0A0C5I0W4 SMALYGFAQGLIQEAGIRIKQLMEQNVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPHHDALIQLHEQRF 5dw8 B 2.40 BS02 CA B 2 E65 D83 I85 T88 E54 D72 I74 T77 3.1.3.25 A0A0C5I0W4 SMALYGFAQGLIQEAGIRIKQLMEQNVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPHHDALIQLHEQRF 5dw8 B 2.40 BS03 2AM B 1 I85 D86 G87 T88 A184 R203 L204 I74 D75 G76 T77 A173 R192 L193 3.1.3.25 A0A0C5I0W4 SMALYGFAQGLIQEAGIRIKQLMEQNVTNVDKATEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNSILVGNRGLHQEISNDYLEPHHDALIQLHEQRF 5dz2 A 2.11 BS01 MG A 1 N229 S233 E237 N222 S226 E230 4.2.3.22,4.2.3.75,4.1.99.16 Q9X839 26598179 QPFQLPHFYLPHPARLNPHLDEARAHSTTWAREMGMLEGSGVWEQSDLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLEKYKRSQDRLAGKAHLDRLPLFMPLGMPEPRNPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESMWELSNINEGRVANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGTRPLRVLMETFSDAVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAADLVNDVLTSRLHQFEHTAFTEVPAVALEKGLTPLEVAAVGAYTKGLQDWQSGGHEWHMRSSRYMNK 5dz2 A 2.11 BS02 212 A 1 V82 F83 D86 R184 N229 S233 R236 E237 R325 Y326 V79 F80 D83 R177 N222 S226 R229 E230 R318 Y319 4.2.3.22,4.2.3.75,4.1.99.16 Q9X839 26598179 QPFQLPHFYLPHPARLNPHLDEARAHSTTWAREMGMLEGSGVWEQSDLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLEKYKRSQDRLAGKAHLDRLPLFMPLGMPEPRNPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESMWELSNINEGRVANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGTRPLRVLMETFSDAVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAADLVNDVLTSRLHQFEHTAFTEVPAVALEKGLTPLEVAAVGAYTKGLQDWQSGGHEWHMRSSRYMNK 5dz2 B 2.11 BS01 MG B 1 N229 S233 E237 N222 S226 E230 4.2.3.22,4.2.3.75,4.1.99.16 Q9X839 26598179 QPFQLPHFYLPHPARLNPHLDEARAHSTTWAREMGMLEGSGVWEQSDLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLEKYKRSQDRLAGKAHLDRLPLFMPLGMPEPRNPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESMWELSNINEGRVANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGTRPLRVLMETFSDAVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAADLVNDVLTSRLHQFEHTAFTEVPAVALEKGLTPLEVAAVGAYTKGLQDWQSGGHEWHMRSSRYMNK 5dz2 B 2.11 BS02 212 B 1 V82 F83 D86 R184 N229 S233 R236 E237 R325 Y326 V79 F80 D83 R177 N222 S226 R229 E230 R318 Y319 4.2.3.22,4.2.3.75,4.1.99.16 Q9X839 26598179 QPFQLPHFYLPHPARLNPHLDEARAHSTTWAREMGMLEGSGVWEQSDLEAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLEKYKRSQDRLAGKAHLDRLPLFMPLGMPEPRNPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESMWELSNINEGRVANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGTRPLRVLMETFSDAVHLRNDLFSYQREVEDEGELSNGVLVLETFFGCTTQEAADLVNDVLTSRLHQFEHTAFTEVPAVALEKGLTPLEVAAVGAYTKGLQDWQSGGHEWHMRSSRYMNK 5e0i A 1.95 BS01 5J6 A 1 F23 P25 D29 L30 T33 L37 W102 I105 S106 T109 F110 Y118 I139 L140 F24 P26 D30 L31 T34 L38 W103 I106 S107 T110 F111 Y119 I140 L141 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i A 1.95 BS02 5J6 F 1 V124 R127 T128 A132 P134 V125 R128 T129 A133 P135 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i B 1.95 BS01 5J6 B 1 F23 P25 D29 L30 T33 L37 W102 I105 S106 T109 F110 Y118 I139 L140 F24 P26 D30 L31 T34 L38 W103 I106 S107 T110 F111 Y119 I140 L141 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVGTNLEDPASRDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i C 1.95 BS01 5J6 B 1 V124 W125 R127 T128 A132 P134 V117 W118 R120 T121 A125 P127 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVGTDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i C 1.95 BS02 5J6 C 1 F23 P25 D29 L30 T33 L37 W102 I105 S106 T109 F110 Y118 L140 F24 P26 D30 L31 T34 L38 W95 I98 S99 T102 F103 Y111 L133 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVGTDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i D 1.95 BS01 5J6 D 1 F23 P25 D29 L30 T33 L37 W102 I105 S106 T109 F110 Y118 L140 F23 P25 D29 L30 T33 L37 W94 I97 S98 T101 F102 Y110 L132 P03147 26598693 MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVSRDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i E 1.95 BS01 5J6 D 1 V124 W125 R127 T128 A132 P134 V115 W116 R118 T119 A123 P125 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWRDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i E 1.95 BS02 5J6 E 1 F23 P25 L30 T33 L37 W102 I105 S106 T109 F110 Y118 I139 L140 F24 P26 L31 T34 L38 W93 I96 S97 T100 F101 Y109 I130 L131 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWRDLVVSYVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e0i F 1.95 BS01 5J6 F 1 F23 P25 D29 L30 T33 L37 W102 I105 S106 T109 F110 Y118 I139 L140 F24 P26 D30 L31 T34 L38 W86 I89 S90 T93 F94 Y102 I123 L124 P03147 26598693 SMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTAAALYRDALESPEHCSPHHTALRQAILCWGDLMTLATWVNTNVGLKFRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAARPPNAPILSTLPETTVENLYF 5e2o A 2.08 BS01 5JM A 1 H40 L41 C42 H57 C58 Y143 L147 I151 D189 A190 C191 K192 G193 D194 S195 T213 S214 W215 G216 G218 C219 G226 V227 Y228 H27 L28 C29 H44 C45 Y134 L137 I141 D182 A183 C184 K185 G186 D187 S188 T206 S207 W208 G209 G211 C212 G219 V220 Y221 3.4.21.27 P03951 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV 5e2p A 2.11 BS01 7P0 A 1 R39 H40 L41 C42 H57 Y143 L147 I151 D189 A190 C191 K192 G193 D194 S195 T213 S214 W215 G216 G218 C219 G226 V227 Y228 R26 H27 L28 C29 H44 Y134 L137 I141 D182 A183 C184 K185 G186 D187 S188 T206 S207 W208 G209 G211 C212 G219 V220 Y221 3.4.21.27 P03951 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV 5e5e A 1.98 BS01 DMS A 1 N62 V63 A64 T70 N62 V63 A64 T70 3.1.27.5 P61823 26609781 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 5e6t A 2.27 BS01 ZN A 1 D304 H306 D85 H87 E6Y5B1 26599362 GSPPFTLPNLPVNNLSHSRVMEPIAQMMSSRNFPASVQFQNGRCTLSGDLLGTTPSSPSDLGAFVGLIAEPGSRVVELSQPNQEDFHAGSAPAPFGFPDFSDCSLTFVVASATTVGERTVNARSPQNFTPALGHITFDEEAPADLFRAHLRNLWDPTEHSFWRIPDYRADVLGSEFAPSVSAPGVGETLLFFMCNVPRLNGANPNPCPCLLPQEWITHFVSERAALQSDVALLNYVNPNTGRVLFEAKLYANGFLTVNLGASDQATLPVDGIFKFVSWVSFYYQLRPV 5e6t B 2.27 BS01 ZN B 1 E296 H353 E73 H130 E6Y5B1 26599362 FTLPNLPVNNLSHSRVMEPIAQMMSSRNFPASVQFQNGRCTLSGDLLGTTPSSPSDLGAFVGLIAEPGSRVVELSQPNQEDFHAGSAPAPFGFPDFSDCSLTFVVASATTVGERTVNARSPQNFTPALGHITFDEEAPADLFRAHLRNLWDPTEHSFWRIPDYRADVLGSEFAPSVSAPGVGETLLFFMCNVPRLNGANPNPCPCLLPQEWITHFVSERAALQSDVALLNYVNPNTGRVLFEAKLYANGFLTVNLGASDQATLPVDGIFKFVSWVSFYYQLRPV 5e6t B 2.27 BS02 ZN B 2 D304 H306 D81 H83 E6Y5B1 26599362 FTLPNLPVNNLSHSRVMEPIAQMMSSRNFPASVQFQNGRCTLSGDLLGTTPSSPSDLGAFVGLIAEPGSRVVELSQPNQEDFHAGSAPAPFGFPDFSDCSLTFVVASATTVGERTVNARSPQNFTPALGHITFDEEAPADLFRAHLRNLWDPTEHSFWRIPDYRADVLGSEFAPSVSAPGVGETLLFFMCNVPRLNGANPNPCPCLLPQEWITHFVSERAALQSDVALLNYVNPNTGRVLFEAKLYANGFLTVNLGASDQATLPVDGIFKFVSWVSFYYQLRPV 5e8g A 2.70 BS01 CO A 1 D361 H363 D83 H85 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8g B 2.70 BS01 CO B 1 D361 H363 D83 H85 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8g C 2.70 BS01 CO C 1 D361 H363 D83 H85 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8g D 2.70 BS01 CO D 1 D361 H363 D83 H85 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i A 3.45 BS01 NUC B 1 Y332 R337 R340 Y341 Y343 K350 R355 Y356 Y54 R59 R62 Y63 Y65 K72 R77 Y78 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i A 3.45 BS02 NUC C 1 Q282 L283 W321 K325 K327 M330 K334 R337 A338 Y341 Y342 K345 Q4 L5 W43 K47 K49 M52 K56 R59 A60 Y63 Y64 K67 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i D 3.45 BS01 NUC E 1 Y332 R337 R340 Y341 Y343 K350 R355 Y356 Y54 R59 R62 Y63 Y65 K72 R77 Y78 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i D 3.45 BS02 NUC F 1 Q282 L283 W321 K325 K327 N329 M330 K334 R337 Y341 Y342 Q4 L5 W43 K47 K49 N51 M52 K56 R59 Y63 Y64 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i G 3.45 BS01 NUC H 1 Y332 R337 R340 Y341 Y343 K350 R355 Y356 Y54 R59 R62 Y63 Y65 K72 R77 Y78 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i G 3.45 BS02 NUC I 1 Q282 L283 W321 K325 K327 N329 M330 K334 R337 Y341 Y342 K345 Q4 L5 W43 K47 K49 N51 M52 K56 R59 Y63 Y64 K67 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i J 3.45 BS01 NUC K 1 Y332 R337 R340 Y341 Y343 K350 R355 Y356 Y54 R59 R62 Y63 Y65 K72 R77 Y78 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8i J 3.45 BS02 NUC L 1 Q282 L283 W321 K325 K327 M330 K334 R337 A338 Y341 Y342 K345 Q4 L5 W43 K47 K49 M52 K56 R59 A60 Y63 Y64 K67 Q01543 GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 5e8r A 2.55 BS01 SAH A 1 Y47 Y48 Y51 M60 R66 G90 A91 L96 E112 A113 P139 V140 E141 E155 M166 S169 Y6 Y7 Y10 M19 R25 G49 A50 L55 E71 A72 P98 V99 E100 E114 M125 S128 2.1.1.-,2.1.1.125 Q96LA8 26598975 ERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED 5e8r A 2.55 BS02 5L6 A 1 Y47 C50 Y51 V56 E59 M60 E155 M157 Y159 H163 E164 H317 W318 Y6 C9 Y10 V15 E18 M19 E114 M116 Y118 H122 E123 H274 W275 2.1.1.-,2.1.1.125 Q96LA8 26598975 ERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED 5e8r B 2.55 BS01 SAH B 1 Y47 Y51 M60 R66 G90 A91 G92 L96 E112 A113 P139 V140 E141 E155 M166 S169 Y8 Y12 M21 R27 G51 A52 G53 L57 E73 A74 P100 V101 E102 E116 M127 S130 2.1.1.-,2.1.1.125 Q96LA8 26598975 KRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAME 5e8r B 2.55 BS02 5L6 B 1 C50 Y51 V56 E59 M60 E155 M157 Y159 H163 E164 H317 W318 C11 Y12 V17 E20 M21 E116 M118 Y120 H124 E125 H276 W277 2.1.1.-,2.1.1.125 Q96LA8 26598975 KRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAME 5ea3 F 2.75 BS01 5NK F 1 F140 D486 E487 F488 D489 F66 D399 E400 F401 D402 P03420 NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKKVKLIKQELDKYKNAVTELQLLMFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFI 5ea4 F 2.30 BS01 5NM F 1 F137 F140 M396 T397 S398 D486 F488 F74 F77 M333 T334 S335 D423 F425 P03420 QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFI 5ea5 F 3.05 BS01 TM3 F 1 F140 D486 E487 F488 K498 F74 D406 E407 F408 K418 P03420 NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIDAKVKLIKQELDKYKNAVTELQLLMQSTPATNFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLTVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFI 5ea6 F 2.75 BS01 5NP F 1 F137 F140 M396 F488 F65 F68 M312 F404 P03420 NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKAKVKLIKQELDKYKNAVTELQLLMQFLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFI 5elh A 1.80 BS01 ZN A 1 C45 C53 C61 H65 C15 C23 C31 H35 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEAL 5elh A 1.80 BS02 ZN A 2 C90 C100 C106 H110 C60 C70 C76 H80 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEAL 5elh A 1.80 BS03 ZN A 3 C130 C140 C147 H151 C100 C110 C117 H121 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAMEAL 5elh B 1.80 BS01 NUC R 1 D115 R118 R119 Y120 Y124 K126 T127 G128 I129 C130 I131 H132 N143 H146 C147 A148 F149 D85 R88 R89 Y90 Y94 K96 T97 G98 I99 C100 I101 H102 N113 H116 C117 A118 F119 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAME 5elh B 1.80 BS02 ZN B 1 C45 C53 C61 H65 C15 C23 C31 H35 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAME 5elh B 1.80 BS03 ZN B 2 C90 C100 C106 H110 C60 C70 C76 H80 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAME 5elh B 1.80 BS04 ZN B 3 C130 C140 C147 H151 C100 C110 C117 H121 Q8BL48 PQHYTYLKEFRTEQCPLFVQHKCTQHRPYTCFHWHFVNQRRRRSIRRRDGTFNYSPDVYCTKYDEATGLCPEGDECPFLHRTTGDTERRYHLRYYKTGICIHETDSKGNCTKNGLHCAFAHGPHDLRSPVYDIRELQAME 5elk A 2.30 BS01 NUC R 1 Y216 Y232 S254 S255 R284 Q287 Q288 F289 I293 K295 S296 T297 K298 N300 D301 R310 F313 C314 A315 F316 Y13 Y29 S51 S52 R81 Q84 Q85 F86 I90 K92 S93 T94 K95 N97 D98 R107 F110 C111 A112 F113 Q8BL48 PRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPL 5elk A 2.30 BS02 ZN A 1 C221 C228 C234 H238 C18 C25 C31 H35 Q8BL48 PRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPL 5elk A 2.30 BS03 ZN A 2 C257 C272 C278 H282 C54 C69 C75 H79 Q8BL48 PRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPL 5elk A 2.30 BS04 ZN A 3 C299 C308 C314 H318 C96 C105 C111 H115 Q8BL48 PRWQETAYVLGNYKTEPCKKPPRLCRQGYACPYYHNSKDRRRSPRKHKYRSSPCPNVKHGDEWGDPGKCENGDACQYCHTRTEQQFHPEIYKSTKCNDMQQAGSCPRGPFCAFAHIEPPPL 5ex7 A 2.60 BS01 NUC B 1 E782 N800 Y829 R847 S848 R875 C890 K891 M893 E915 F916 P917 N933 R934 Y959 I961 N976 H977 N978 H1001 Q1003 C1004 E25 N43 Y72 R90 S91 R118 C133 K134 M136 E158 F159 P160 N176 R177 Y202 I204 N219 H220 N221 H244 Q246 C247 Q8MQJ9 QIKRQKMIYHCKFGEFGVMEGQFTEPSGVAVNAQNDIIVADTNNHRIQIFDKEGRFKFQFGECGKRDSQLLYPNRVAVVRNSGDIIVTERSPTHQIQIYNQYGQFVRKFGATILQHPRGVTVDNKGRIIVVECKVMRVIIFDQNGNVLHKFGCSKHLEFPNGVVVNDKQEIFISDNRAHCVKVFNYEGQYLRQIGGEGITNYPIGVGINSNGEILIADNHNNFNLTIFTQDGQLISALESKVKHAQCFDVALMDDGSVVLASKDYRLYIYRYVQ 5eyu A 1.72 BS01 NAD A 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 G257 C289 H336 E390 F392 I148 T149 P150 W151 N152 K175 S177 E178 G208 G212 F226 G228 G229 T232 H235 I236 E250 G252 C284 H331 E385 F387 1.2.1.8 Q9L4P8 HLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5eyu B 1.72 BS01 NAD B 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 D218 F231 G233 G234 T237 H240 I241 E255 G257 C289 H336 E390 F392 I148 T149 P150 W151 N152 K175 S177 E178 G208 G212 D213 F226 G228 G229 T232 H235 I236 E250 G252 C284 H331 E385 F387 1.2.1.8 Q9L4P8 HLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5eyu C 1.72 BS01 NAD C 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 G257 C289 H336 E390 F392 I148 T149 P150 W151 N152 K175 S177 E178 G208 G212 F226 G228 G229 T232 H235 I236 E250 G252 C284 H331 E385 F387 1.2.1.8 Q9L4P8 HLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5eyu D 1.72 BS01 NAD D 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 D218 F231 G233 G234 T237 H240 I241 E255 G257 C289 H336 E390 F392 I148 T149 P150 W151 N152 K175 S177 E178 G208 G212 D213 F226 G228 G229 T232 H235 I236 E250 G252 C284 H331 E385 F387 1.2.1.8 Q9L4P8 HLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5ez3 A 2.15 BS01 FAD A 1 M190 M192 T193 G197 G198 T199 F224 S226 K268 V429 W433 E434 S436 N438 L442 M179 M181 T182 G186 G187 T188 F213 S215 K257 V418 W422 E423 S425 N427 L431 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPA 5ez3 A 2.15 BS02 FAD B 1 R332 V334 F335 L339 Q342 M345 E407 C408 G410 G411 R321 V323 F324 L328 Q331 M334 E396 C397 G399 G400 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPA 5ez3 B 2.15 BS01 FAD A 1 R332 V334 F335 L339 Q342 M345 E407 C408 G410 G411 R321 V323 F324 L328 Q331 M334 E396 C397 G399 G400 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS 5ez3 B 2.15 BS02 FAD B 1 M190 M192 T193 G197 G198 T199 F224 S226 K268 V429 W433 E434 S436 N438 L442 M179 M181 T182 G186 G187 T188 F213 S215 K257 V418 W422 E423 S425 N427 L431 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS 5ez3 C 2.15 BS01 FAD C 1 M190 M192 T193 G197 G198 T199 F224 S226 K268 V429 I432 W433 E434 S436 N438 L442 M179 M181 T182 G186 G187 T188 F213 S215 K257 V418 I421 W422 E423 S425 N427 L431 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS 5ez3 C 2.15 BS02 FAD D 1 R332 V334 F335 L339 Q342 M345 E407 C408 G410 G411 Y414 R321 V323 F324 L328 Q331 M334 E396 C397 G399 G400 Y403 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS 5ez3 D 2.15 BS01 FAD C 1 R332 V334 F335 L339 Q342 M345 E407 C408 G410 G411 R321 V323 F324 L328 Q331 M334 E396 C397 G399 G400 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS 5ez3 D 2.15 BS02 FAD D 1 M190 M192 T193 G197 G198 T199 F224 S226 K268 V429 W433 E434 S436 N438 V439 L442 M179 M181 T182 G186 G187 T188 F213 S215 K257 V418 W422 E423 S425 N427 V428 L431 1.3.8.- Q8YC61 KTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS 5ez4 A 2.11 BS01 NAD A 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 G257 C289 K339 E390 F392 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 G257 C289 K339 E390 F392 1.2.1.8 Q9L4P8 MELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5ez4 B 2.11 BS01 NAD B 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 L256 G257 C289 H336 K339 E390 F392 I152 T153 P154 W155 N156 K179 S181 E182 G212 G216 F230 G232 G233 T236 H239 I240 E254 L255 G256 C288 H335 K338 E389 F391 1.2.1.8 Q9L4P8 ELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5ez4 C 2.11 BS01 NAD C 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 G257 C289 K339 E390 F392 I155 T156 P157 W158 N159 K182 S184 E185 G215 G219 F233 G235 G236 T239 H242 I243 E257 G259 C291 K341 E392 F394 1.2.1.8 Q9L4P8 QGMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5ez4 D 2.11 BS01 NAD D 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 G233 G234 T237 H240 I241 E255 L256 G257 C289 H336 K339 E390 F392 I150 T151 P152 W153 N154 K177 S179 E180 G210 G214 F228 G230 G231 T234 H237 I238 E252 L253 G254 C286 H333 K336 E387 F389 1.2.1.8 Q9L4P8 LKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHMLFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 5fp2 A 2.97 BS01 III X 1 E132 L134 Y142 N152 I154 E71 L73 Y81 N91 I93 Q9I527 KQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTRQIDIRGMGPENTLILVDGKPVSNWVPPEEVERIEVLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPLTEALSFRAYGSANKTDSDDGVRNRDLSGMLSWQVTPDQVVDFEAGFSRQGNTNRMYRENYAITHNGTWSFGTSRFVAQYDSTRNNRLSASKLENYRLSGELNLPLHALFEQVLTVGAEWNKETLNDPSSSPKSKAEIRALYVEDNIELRPGTMLTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLLYYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKIVAPNILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSPEYTLNSTLDWQASERLSTQLTSTIYGGTYGIWGVSAGYTFSENLSVRGGVSNLFDKRLEPGRAYYVSMTTSFL 5fp2 B 2.97 BS01 III Z 1 E132 L134 Y142 N152 I154 M426 E76 L78 Y86 N96 I98 M295 Q9I527 KQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTQIDIRGMGPENTLILVDGKPVSSRNSVRNWVPPEEVERIEVLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPLTEALSFRAYGSANKTDSDDGVRNRDLSGMLSWQVTPDQVVDFEAGFSRQGNIAETNRMYRENYAITHNGTWSFGTSRFVAQYDSTRNNRLFSASKLENYRLSGELNLPLHALFEQVLTVGAEWNKETLNDPSSLRSPKSKAEIRALYVEDNIELRPGTMLTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLLYTRGNGCPIQTSSGGCYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKIVAPLDVMGQTGTGNNILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSKDPEYTLNSTLDWQASERLSTQLTSTIYGGTYGIWGVSAGYTFSENLSVRGGVSNLFDKRLEPGRAYYVSMTTSFL 5fp5 A 2.16 BS01 1Y6 A 1 I10 A31 K33 V64 F80 E81 L83 L134 A144 D145 I10 A30 K32 V52 F65 E66 L68 L119 A129 D130 2.7.11.22 P24941 MENFQKVEKIGEGYGVVYKARNKLTGEVVALKKITAIREISLLKELNHPNIVKLLDVIHTLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPH 5fp5 A 2.16 BS02 1Y6 A 2 V226 R245 H268 Y269 V195 R214 H237 Y238 2.7.11.22 P24941 MENFQKVEKIGEGYGVVYKARNKLTGEVVALKKITAIREISLLKELNHPNIVKLLDVIHTLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPH