2mx6 A BS01 III B 1 F261 L262 G263 I264 S265 I266 M284 D315 V318 L321 R322 V325 F14 L15 G16 I17 S18 I19 M37 D68 V71 L74 R75 V78 P51141 NIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAK 3jbr A 4.20 BS01 CA A 1 F1013 G1322 F769 G1026 P07293 26680202 FCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLTVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYYIGTDIVATVENEKPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAQQLEEDLRGYMSWITQCHDLVKSRVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDIANRVLLSLFTIEMLLKMYGLGLRQYFMSIFNRFDCFVVCSGILELLLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSTISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDLSKMTEEECRGYYYVYKDGDPTQMELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYRAIDSNEEDMGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYHQSEEMNHISDILNVAFTIIFTLEMILKLLAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTRISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTNRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4roc A 1.90 BS01 NUC N 1 S66 S68 R107 A108 A109 R110 L111 K114 D147 S150 M154 S246 S2 S4 R43 A44 A45 R46 L47 K50 D83 S86 M90 S182 Q9HAW0 26638071 VSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQA 4roc A 1.90 BS02 NUC T 1 G105 A108 A109 R110 K113 G219 R220 H221 Y260 P261 R265 C361 G41 A44 A45 R46 K49 G155 R156 H157 Y196 P197 R201 C256 Q9HAW0 26638071 VSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQA 4roc B 1.90 BS01 NUC N 1 V169 T171 F197 F214 S216 K218 V220 Q256 N257 V259 F288 R294 V301 L303 T313 G314 V13 T15 F41 F58 S60 K62 V64 Q100 N101 V103 F132 R138 V145 L147 T157 G158 P20226 26638071 GPSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKG 4roc B 1.90 BS02 NUC T 1 Q166 N167 V169 R196 F197 R203 R208 T210 L212 T222 G223 V259 F288 P289 L303 F305 S307 K309 V311 Q10 N11 V13 R40 F41 R47 R52 T54 L56 T66 G67 V103 F132 P133 L147 F149 S151 K153 V155 P20226 26638071 GPSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKG 4rod A 2.70 BS01 NUC N 1 S66 S68 R107 A108 A109 R110 L111 K114 D147 S1 S3 R42 A43 A44 R45 L46 K49 D82 Q9HAW0 26638071 SRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDGLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQA 4rod A 2.70 BS02 NUC T 1 G105 A108 R110 K113 G219 R220 H221 Y260 P261 R265 C361 G40 A43 R45 K48 G154 R155 H156 Y195 P196 R200 C256 Q9HAW0 26638071 SRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDGLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQA 4roe A 2.20 BS01 NUC N 1 R107 A109 R110 L111 K114 D147 S150 M154 R44 A46 R47 L48 K51 D84 S87 M91 Q9HAW0 26638071 QVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQAARQA 4roe A 2.20 BS02 NUC T 1 K113 G219 R220 H221 Y260 P261 R265 C361 K50 G156 R157 H158 Y197 P198 R202 C257 Q9HAW0 26638071 QVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLANVDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQSLVRSAFRDLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTPQEVRDFQRAQAARQA 4rx6 A 2.60 BS01 ATP A 1 V16 G44 R67 P95 G96 G98 K99 V12 G40 R55 P83 G84 G86 K87 Q07428 25691471 AMSGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 4rx6 A 2.60 BS02 ATP B 1 T35 S36 L37 T38 E71 V73 L121 T31 S32 L33 T34 E59 V61 L109 Q07428 25691471 AMSGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 4rx6 B 2.60 BS01 ATP B 2 S36 L37 T38 E71 I72 V73 R112 S30 L31 T32 E65 I66 V67 R106 Q07428 25691471 SGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAHTELYRGVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 4rx6 B 2.60 BS02 ATP B 1 V16 G44 R67 P95 G96 D97 G98 K99 V10 G38 R61 P89 G90 D91 G92 K93 Q07428 25691471 SGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKAHTELYRGVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 4rx6 D 2.60 BS01 ATP A 1 T35 S36 L37 T38 E71 V73 T29 S30 L31 T32 E57 V59 Q07428 25691471 SGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 4rx6 D 2.60 BS02 ATP B 3 V16 G44 R67 G98 K99 F101 V10 G38 R53 G84 K85 F87 Q07428 25691471 SGQMFKVEIVTRPANFEKLKQELGKIGVTSLTFSNVHGCGLQKVKIESNVYERLKIEIVVSKVPVDQVTETAKRVLKTGSPGDGKIFVYEISNTINIRTGEEGPEAL 4rzu B 2.80 BS01 ADP B 1 G14 S15 G16 K17 S18 S19 R138 K192 P194 I197 G12 S13 G14 K15 S16 S17 R136 K190 P192 I195 2.7.4.9 Q970Q8 KGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTPLTFSLIHATDFSDRYERYILPMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAIKPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLSPEEGFLKYQGLITEVYDKLVKDENFIVIDGTKTPKEIQIQIRKFVGELI 4rzu B 2.80 BS02 MG B 1 S18 D92 S16 D90 2.7.4.9 Q970Q8 KGVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSSDWIHDIIKEAKKKDLLTPLTFSLIHATDFSDRYERYILPMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAIKPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLSPEEGFLKYQGLITEVYDKLVKDENFIVIDGTKTPKEIQIQIRKFVGELI 4rzu A 2.80 BS01 ADP A 1 D13 G14 S15 G16 K17 S18 S19 R138 S142 K192 P194 D10 G11 S12 G13 K14 S15 S16 R134 S138 K188 P190 2.7.4.9 Q970Q8 GVLIAFEGIDGSGKSSQATLLKDWIELKRDVYLTEWNSDWIHDIIKEAKKKDLLTPLTFSLIHATDFSDRYERYILPMLKSGFIVISDRYIYTAYARDSVRGVDIDWVKKLYSFAIKPDITFYIRVSPDIALERIKKSKRKIKPQEAGADIFPGLSPEEGFLKYQGLITEVYDKLVKDENFIVIDGTKTPKEIQIQIRKFVGELI 4wuu A 3.05 BS01 III C 1 Y7 M45 E63 K66 V67 H70 T73 V76 D77 T80 L81 Y84 R97 Y99 Y116 Y123 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 Y7 M45 E63 K66 V67 H70 T73 V76 D77 T80 L81 Y84 R97 Y99 Y116 Y123 T143 K146 W147 V152 Q155 L156 Y159 T163 W167 Y171 P01892 26688548 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE 4wuu D 3.05 BS01 III C 1 N32 W92 D94 N31 W91 D93 26688548 AVVTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQVPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGWVFGGGTKLTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT 4wuu E 3.05 BS01 III C 1 S102 G103 Y104 S102 G103 Y104 26688548 QMQLVQSGAEVKEPGESLRISCKGSGYSFTNFWISWVRQMPGKGLEWMGRVDPGYSYSTYSPSFQGHVTISADKSTSTAYLQWNSLKASDTAMYYCARVQYSGYYDWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS 4xek A 1.79 BS01 III C 1 K911 G914 L915 L917 R918 I921 D925 K944 N947 L950 M957 R958 K43 G46 L47 L49 R50 I53 D57 K76 N79 L82 M89 R90 2.7.10.2 Q14289 HMANLDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAH 4xeo A 1.38 BS01 A5A A 1 A44 R77 Y93 H94 H95 F98 M100 W176 E213 I214 N216 V218 D239 T240 G241 G243 R246 A41 R74 Y89 H90 H91 F94 M96 W172 E209 I210 N212 V214 D235 T236 G237 G239 R242 6.1.1.7 P49588 TLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILHRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSR 4xeo A 1.38 BS02 MG A 1 E189 E213 E185 E209 6.1.1.7 P49588 TLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILHRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSR 4xev A 2.01 BS01 III C 1 V907 V910 K911 G914 L915 L917 R918 I921 D925 N947 L950 A951 M957 R958 V36 V39 K40 G43 L44 L46 R47 I50 D54 N76 L79 A80 M86 R87 2.7.10.2 Q14289 NLDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHGGEELDALLEELER 4xev D 2.01 BS01 III F 1 K911 G914 L915 L917 R918 I921 D925 N947 L950 I954 M957 R958 Q961 K39 G42 L43 L45 R46 I49 D53 N75 L78 I82 M85 R86 Q89 2.7.10.2 Q14289 LDRTDDLVYLNVMELVRAVLELKNELSQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEAKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHGMEELDALLEELER 4xg3 A 2.30 BS01 X3G A 1 L377 V385 A400 V433 M448 E449 M450 A451 G454 P455 K458 R498 N499 L501 D512 L15 V18 A33 V61 M76 E77 M78 A79 G82 P83 K86 R126 N127 L129 D140 2.7.10.2 P43405 VYLDRKLLTLEDKELGTVKKGYYQMKKVVKTVAVKILKPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVV 4xg5 A 2.80 BS01 X5G A 1 L377 A400 M448 E449 M450 A451 G454 P455 R498 N499 L501 D512 L15 A38 M82 E83 M84 A85 G88 P89 R132 N133 L135 D146 2.7.10.2 P43405 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN 4xg8 A 2.40 BS01 X8G A 1 L377 G378 V385 A400 M448 E449 M450 A451 G454 P455 R498 N499 L501 D512 L12 G13 V18 A31 M74 E75 M76 A77 G80 P81 R124 N125 L127 D138 2.7.10.2 P43405 DRKLLTLEDKELGSGGTVKKGYYQMVVKTVAVKILDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN 4ylq L 1.40 BS09 XYS L 1 Q49 Q66 S67 Y68 Q49 Q66 S67 Y68 3.4.21.21 P08709 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEK 4ylq L 1.40 BS10 XYS L 2 Q66 S67 Y68 R79 Q66 S67 Y68 R79 3.4.21.21 P08709 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEK 4ylq L 1.40 BS11 FUC L 1 G58 G59 S60 F71 C72 L73 G58 G59 S60 F71 C72 L73 3.4.21.21 P08709 ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEK 4ylq H 1.40 BS01 0Z7 H 1 H57 G97 T98 T99 D102 D189 S190 C191 K192 G193 D194 S195 S214 W215 G216 G218 C219 G226 H41 G85 T86 T87 D90 D181 S182 C183 K184 G185 D186 S187 S206 W207 G208 G210 C211 G218 3.4.21.21 P08709 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASFPGKITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP 4z68 A 1.86 BS01 III E 1 R525 S527 F532 G535 Y536 N537 L560 N565 Y569 G570 H571 D589 W591 F593 E598 K602 R36 S38 F43 G46 Y47 N48 L71 N76 Y80 G81 H82 D100 W102 F104 E109 K113 2.4.2.30 Q9H2K2 SEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLR 4z6a H 2.25 BS01 0Z6 H 1 H57 G97 T98 T99 D189 S190 C191 K192 G193 D194 S195 V213 S214 W215 G216 Q217 G218 C219 G226 H41 G85 T86 T87 D181 S182 C183 K184 G185 D186 S187 V205 S206 W207 G208 Q209 G210 C211 G218 3.4.21.21 P08709 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP 4zma H 2.30 BS01 0Z6 H 1 H57 C58 G97 T98 T99 D189 S190 C191 K192 D194 S195 V213 S214 W215 G216 Q217 G218 C219 G226 H41 C42 G85 T86 T87 D179 S180 C181 K182 D184 S185 V203 S204 W205 G206 Q207 G208 C209 G216 3.4.21.21 P08709 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASGKITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP 4zxh A 2.70 BS01 PNS A 1 G23 Y37 P279 T298 F333 S334 V337 R344 N349 F357 Q398 L399 H1005 S1006 G25 Y39 P281 T300 F335 S336 V339 R346 N351 F359 Q400 L401 H1001 S1002 GHMNNLARLEPEVLSRHAISSEQLGIWYIQRLEPTCSAYNMVVAFDVKVNQSLGNKPIEILEAVMHDYPLLRVSMPANDQGIEQLIWDRVYPNIIFSDARHIEASDLTQLVEQDTKQPFDLTQPPLWRIHCYECGQNHYVIAFVIHHALMDFWSIGLLLRDVSKRFGLVAESDAVNGIEFVQYADKQQSSVIDDTDESLIFWKNALKHAPHVHSIPLDYPRPAVQQHKGSSLVFRVSESVSSGLVNLAKDYEITLFGLVLSGFYVLLHKLSNENNLVIATPVAGRLERSLRNALGQFVNTIAIHMDIDADQTLRQFTQQVQEQLRQSLKHQKIAFSRVVEAVSPKRDGSINPLAQIGMFWERLGGMDEFKELLLPIQTPATLVGQDLTLGSFPVRQQEGQLDITLEMGGEYQGELVGVLKYNTDLFSAQSAENMVQLLQAVLSEMVAHPERKIVELDIAPDYKDGIQFEALRGKATDYAQHDLFAMILKQIDERGDNHALTSHTVSYRELGQHIAGIAEYLRAHGITQGDRVGLMLDRTALLPAAILGIWAAGAAYVPLDPNFPTERLQNIIEDAEPKVILTQTELMDGLNVSVPRLDINQAGVVALEQVRETLAFGDIAYVMYTSKPKGVRIGHPSIINFLLSMNDRLQVTTETQLLAITTYAFDISILELLIPLMYGGVVHVCPREVSQDGIQLVDYLNAKSINVLQATPATWKMLLDSEWSGNAGLTALCGGEALDTILAEKLLGKVGCLWNVYGPTETTVWSSAARITDAKYIDLGEPLANTQLYVLDEQQRLVPPGVMGELWIGGDGLAVDYWQRPELTDAQFRTLPSLPNAGRLYRTGDKVCLRTDGRLTHHGRLDFQVKIRGFRIELGEIENVLKQIDGITDAVVLVKTTGDNDQKLVAYVTGQELDIAGLKKNLQIHLPAYMVPSAFIRLDEFPMTANKKLDRKAFPEPIFEQSNDYVAPRDPIEIELCTTFEQILSVKRVGIHDDFFELGGHSLLAVKLVNHLKKAFGTELSVALLAQYSTVERLGEIIRENKEIKPSIVIELRRGTYEQPLWLFHPIGGSTFCYMELSRHLNPNRTLRAIQSPGLIEADAAEVAIEEMATLYIAEMQKMQPQGPYFLGGWCFGGAIAYEISRQLRQMGQQVTGIVMIDTRAPIPENVPEDADDAMLLSWFARDLAAPYGKKLTIPAQYLRELSPDQMFDHVLKEAKAINVLPLDADPSDFRLYFDTYLANGIALQTYFPEPEDFPILLVKAKDEQEDFGESLGWDQLVKDTLTQVDLPGDHSSIMYAENVVAVAQTIDQMYPIP 4zxi A 2.90 BS01 PNS A 1 G23 I27 Y37 H145 T298 F333 S334 V337 R344 N349 P350 H1005 S1006 G25 I29 Y39 H147 T300 F335 S336 V339 R346 N351 P352 H1001 S1002 GHMNNLARLEPEVLSRHAISSEQLGIWYIQRLEPTCSAYNMVVAFDVKVNQSLGNKPIEILEAVMHDYPLLRVSMPANDQGIEQLIWDRVYPNIIFSDARHIEASDLTQLVEQDTKQPFDLTQPPLWRIHCYECGQNHYVIAFVIHHALMDFWSIGLLLRDVSKRFGLVAESDAVNGIEFVQYADKQQSSVIDDTDESLIFWKNALKHAPHVHSIPLDYPRPAVQQHKGSSLVFRVSESVSSGLVNLAKDYEITLFGLVLSGFYVLLHKLSNENNLVIATPVAGRLERSLRNALGQFVNTIAIHMDIDADQTLRQFTQQVQEQLRQSLKHQKIAFSRVVEAVSPKRDGSINPLAQIGMFWERLGGMDEFKELLLPIQTPATLVGQDLTLGSFPVRQQEGQLDITLEMGGEYQGELVGVLKYNTDLFSAQSAENMVQLLQAVLSEMVAHPERKIVELDIAPDYKDGIQFEALRGKATDYAQHDLFAMILKQIDERGDNHALTSHTVSYRELGQHIAGIAEYLRAHGITQGDRVGLMLDRTALLPAAILGIWAAGAAYVPLDPNFPTERLQNIIEDAEPKVILTQTELMDGLNVSVPRLDINQAGVVALEQVRETLAFGDIAYVMYTSKPKGVRIGHPSIINFLLSMNDRLQVTTETQLLAITTYAFDISILELLIPLMYGGVVHVCPREVSQDGIQLVDYLNAKSINVLQATPATWKMLLDSEWSGNAGLTALCGGEALDTILAEKLLGKVGCLWNVYGPTETTVWSSAARITDAKYIDLGEPLANTQLYVLDEQQRLVPPGVMGELWIGGDGLAVDYWQRPELTDAQFRTLPSLPNAGRLYRTGDKVCLRTDGRLTHHGRLDFQVKIRGFRIELGEIENVLKQIDGITDAVVLVKTTGDNDQKLVAYVTGQELDIAGLKKNLQIHLPAYMVPSAFIRLDEFPMTANKKLDRKAFPEPIFEQSNDYVAPRDPIEIELCTTFEQILSVKRVGIHDDFFELGGHSLLAVKLVNHLKKAFGTELSVALLAQYSTVERLGEIIRENKEIKPSIVIELRRGTYEQPLWLFHPIGGSTFCYMELSRHLNPNRTLRAIQSPGLIEADAAEVAIEEMATLYIAEMQKMQPQGPYFLGGWCFGGAIAYEISRQLRQMGQQVTGIVMIDTRAPIPENVPEDADDAMLLSWFARDLAAPYGKKLTIPAQYLRELSPDQMFDHVLKEAKAINVLPLDADPSDFRLYFDTYLANGIALQTYFPEPEDFPILLVKAKDEQEDFGESLGWDQLVKDTLTQVDLPGDHSSIMYAENVVAVAQTIDQMYPIP 4zxi A 2.90 BS02 GLY A 1 F669 D670 I671 G739 G762 P763 T764 V768 W769 K952 F665 D666 I667 G735 G758 P759 T760 V764 W765 K948 GHMNNLARLEPEVLSRHAISSEQLGIWYIQRLEPTCSAYNMVVAFDVKVNQSLGNKPIEILEAVMHDYPLLRVSMPANDQGIEQLIWDRVYPNIIFSDARHIEASDLTQLVEQDTKQPFDLTQPPLWRIHCYECGQNHYVIAFVIHHALMDFWSIGLLLRDVSKRFGLVAESDAVNGIEFVQYADKQQSSVIDDTDESLIFWKNALKHAPHVHSIPLDYPRPAVQQHKGSSLVFRVSESVSSGLVNLAKDYEITLFGLVLSGFYVLLHKLSNENNLVIATPVAGRLERSLRNALGQFVNTIAIHMDIDADQTLRQFTQQVQEQLRQSLKHQKIAFSRVVEAVSPKRDGSINPLAQIGMFWERLGGMDEFKELLLPIQTPATLVGQDLTLGSFPVRQQEGQLDITLEMGGEYQGELVGVLKYNTDLFSAQSAENMVQLLQAVLSEMVAHPERKIVELDIAPDYKDGIQFEALRGKATDYAQHDLFAMILKQIDERGDNHALTSHTVSYRELGQHIAGIAEYLRAHGITQGDRVGLMLDRTALLPAAILGIWAAGAAYVPLDPNFPTERLQNIIEDAEPKVILTQTELMDGLNVSVPRLDINQAGVVALEQVRETLAFGDIAYVMYTSKPKGVRIGHPSIINFLLSMNDRLQVTTETQLLAITTYAFDISILELLIPLMYGGVVHVCPREVSQDGIQLVDYLNAKSINVLQATPATWKMLLDSEWSGNAGLTALCGGEALDTILAEKLLGKVGCLWNVYGPTETTVWSSAARITDAKYIDLGEPLANTQLYVLDEQQRLVPPGVMGELWIGGDGLAVDYWQRPELTDAQFRTLPSLPNAGRLYRTGDKVCLRTDGRLTHHGRLDFQVKIRGFRIELGEIENVLKQIDGITDAVVLVKTTGDNDQKLVAYVTGQELDIAGLKKNLQIHLPAYMVPSAFIRLDEFPMTANKKLDRKAFPEPIFEQSNDYVAPRDPIEIELCTTFEQILSVKRVGIHDDFFELGGHSLLAVKLVNHLKKAFGTELSVALLAQYSTVERLGEIIRENKEIKPSIVIELRRGTYEQPLWLFHPIGGSTFCYMELSRHLNPNRTLRAIQSPGLIEADAAEVAIEEMATLYIAEMQKMQPQGPYFLGGWCFGGAIAYEISRQLRQMGQQVTGIVMIDTRAPIPENVPEDADDAMLLSWFARDLAAPYGKKLTIPAQYLRELSPDQMFDHVLKEAKAINVLPLDADPSDFRLYFDTYLANGIALQTYFPEPEDFPILLVKAKDEQEDFGESLGWDQLVKDTLTQVDLPGDHSSIMYAENVVAVAQTIDQMYPIP 4zxi A 2.90 BS03 AMP A 1 T625 S626 G739 E740 A741 N759 V760 Y761 P763 D849 H861 R864 K952 T625 S626 G735 E736 A737 N755 V756 Y757 P759 D845 H857 R860 K948 GHMNNLARLEPEVLSRHAISSEQLGIWYIQRLEPTCSAYNMVVAFDVKVNQSLGNKPIEILEAVMHDYPLLRVSMPANDQGIEQLIWDRVYPNIIFSDARHIEASDLTQLVEQDTKQPFDLTQPPLWRIHCYECGQNHYVIAFVIHHALMDFWSIGLLLRDVSKRFGLVAESDAVNGIEFVQYADKQQSSVIDDTDESLIFWKNALKHAPHVHSIPLDYPRPAVQQHKGSSLVFRVSESVSSGLVNLAKDYEITLFGLVLSGFYVLLHKLSNENNLVIATPVAGRLERSLRNALGQFVNTIAIHMDIDADQTLRQFTQQVQEQLRQSLKHQKIAFSRVVEAVSPKRDGSINPLAQIGMFWERLGGMDEFKELLLPIQTPATLVGQDLTLGSFPVRQQEGQLDITLEMGGEYQGELVGVLKYNTDLFSAQSAENMVQLLQAVLSEMVAHPERKIVELDIAPDYKDGIQFEALRGKATDYAQHDLFAMILKQIDERGDNHALTSHTVSYRELGQHIAGIAEYLRAHGITQGDRVGLMLDRTALLPAAILGIWAAGAAYVPLDPNFPTERLQNIIEDAEPKVILTQTELMDGLNVSVPRLDINQAGVVALEQVRETLAFGDIAYVMYTSKPKGVRIGHPSIINFLLSMNDRLQVTTETQLLAITTYAFDISILELLIPLMYGGVVHVCPREVSQDGIQLVDYLNAKSINVLQATPATWKMLLDSEWSGNAGLTALCGGEALDTILAEKLLGKVGCLWNVYGPTETTVWSSAARITDAKYIDLGEPLANTQLYVLDEQQRLVPPGVMGELWIGGDGLAVDYWQRPELTDAQFRTLPSLPNAGRLYRTGDKVCLRTDGRLTHHGRLDFQVKIRGFRIELGEIENVLKQIDGITDAVVLVKTTGDNDQKLVAYVTGQELDIAGLKKNLQIHLPAYMVPSAFIRLDEFPMTANKKLDRKAFPEPIFEQSNDYVAPRDPIEIELCTTFEQILSVKRVGIHDDFFELGGHSLLAVKLVNHLKKAFGTELSVALLAQYSTVERLGEIIRENKEIKPSIVIELRRGTYEQPLWLFHPIGGSTFCYMELSRHLNPNRTLRAIQSPGLIEADAAEVAIEEMATLYIAEMQKMQPQGPYFLGGWCFGGAIAYEISRQLRQMGQQVTGIVMIDTRAPIPENVPEDADDAMLLSWFARDLAAPYGKKLTIPAQYLRELSPDQMFDHVLKEAKAINVLPLDADPSDFRLYFDTYLANGIALQTYFPEPEDFPILLVKAKDEQEDFGESLGWDQLVKDTLTQVDLPGDHSSIMYAENVVAVAQTIDQMYPIP 4zxj A 2.80 BS01 4T8 A 1 F647 D648 V649 R673 V693 S722 G723 E724 A725 N744 L745 Y746 G747 P748 T749 V753 D754 I775 D840 Y852 K861 R863 G864 Q865 R866 S1006 F644 D645 V646 R670 V690 S719 G720 E721 A722 N741 L742 Y743 G744 P745 T746 V750 D751 I772 D837 Y849 K858 R860 G861 Q862 R863 S1003 2.7.7.- P11454 HLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDSPLLARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALTFELPEIIDLRTNIDPHGTAQALMQADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTWLRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGRSASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFMRRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRDSGRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLELALFPDVHGDLSIEILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQLNATQVEIPETTLSALVAEQAAKTPDAPALADARYLFSYREMREQVVALANLLRERGVKPGDSVAVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRFSDVPNLTSLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRLLWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFFAEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSDDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSGLPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQAPGRAPKAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQVARQVTPGQVMVASTVAKLATIIDAE 5a0e A 1.25 BS01 III C 1 R55 F60 Q63 G72 A101 N102 A103 G104 P105 Q111 F113 W121 L122 H126 R55 F60 Q63 G72 A101 N102 A103 G104 P105 Q111 F113 W121 L122 H126 5.2.1.8 26679998 SGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5a0e B 1.25 BS01 III E 1 R55 F60 M61 Q63 G72 A101 N102 Q111 F113 W121 L122 H126 R54 F59 M60 Q62 G71 A100 N101 Q110 F112 W120 L121 H125 5.2.1.8 26679998 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 5a0q H 3.50 BS01 KNM H 1 T1 T20 T21 T22 K33 R45 G47 S48 A49 G129 S130 T1 T20 T21 T22 K33 R45 G47 S48 A49 G124 S125 3.4.25.1 26133119 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQV 5a0q I 3.50 BS01 KNM I 1 T1 A20 T21 E22 A46 G47 A49 T52 G128 S129 T1 A20 T21 E22 A46 G47 A49 T52 G128 S129 3.4.25.1 26133119 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPYRCEKG 5a0q L 3.50 BS01 KNM L 1 T1 A20 T21 A22 K33 M45 G47 A49 T1 A20 T21 A22 K33 M45 G47 A49 3.4.25.1 26133119 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVAD 5azf A 1.60 BS01 III C 1 E17 I21 R28 P30 K46 K48 Y49 L50 V51 P52 F60 L63 I64 R67 F104 E20 I24 R31 P33 K49 K51 Y52 L53 V54 P55 F63 L66 I67 R70 F107 Q09490 GPHMKWAYKEENNFEKRRAEGDKIRRKYPDRIPVIVEKAPKSKLHDLDKKKYLVPSDLTVGQFYFLIRKRIQLRPEDALFFFVNNVIPQTMTTMGQLYQDHHEEDLFLYIAYSDESVYG 5azf B 1.60 BS01 III D 1 E17 I21 R28 P30 K46 K48 Y49 L50 V51 P52 F60 R67 F104 E20 I24 R31 P33 K49 K51 Y52 L53 V54 P55 F63 R70 F107 Q09490 GPHMKWAYKEENNFEKRRAEGDKIRRKYPDRIPVIVEKAPKSKLHDLDKKKYLVPSDLTVGQFYFLIRKRIQLRPEDALFFFVNNVIPQTMTTMGQLYQDHHEEDLFLYIAYSDESVYG 5azg A 1.81 BS01 III C 1 E17 I21 Y25 R28 K48 Y49 L50 P52 F60 R67 F104 E20 I24 Y28 R31 K51 Y52 L53 P55 F63 R70 F107 Q09490 GPHMKWAYKEENNFEKRRAEGDKIRRKYPDRIPVIVEKAPKSKLHDLDKKKYLVPSDLTVGQFYFLIRKRIQLRPEDALFFFVNNVIPQTMTTMGQLYQDHHEEDLFLYIAYSDESVYG 5bvg A 1.60 BS03 SE B 1 R93 M112 R90 M109 1.18.6.1 P07328 26673079 MSREEVESLIQEVLEVYPEKARKDRNKHLAVNDPAVTQSKKCIISNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQYSRAGRRNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGLIGDDIESVSKVKGAELSKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVLGKRDEDTTFASTPYDVAIIGDYNIGGDAWSSRILLEEMGLRCVAQWSGDGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYNFFGPTKTIESLRAIAAKFDESIQKKCEEVIAKYKPEWEAVVAKYRPRLEGKRVMLYIGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYDRTMKEMGDSTLLYDDVTGYEFEEFVKRIKPDLIGSGIKEKFIFQKMGIPFRQMHSWDYSGPYHGFDGFAIFARDMDMTLNNPCWKKLQAPWE 5bvg B 1.60 BS03 SE B 1 N65 F450 R453 N64 F449 R452 1.18.6.1 P07329 26673079 SQQVDKIKASYPLFLDQDYKDMLAKKRDGFEEKYPQDKIDEVFQWTTTKEYQELNFQREALTVNPAKACQPLGAVLCALGFEKTMPYVHGSQGCVAYFRSYFNRHFREPVSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYKPDMIAVSTTCMAEVIGDDLNAFINNSKKEGFIPDEFPVPFAHTPSFVGSHVTGWDNMFEGIARYFTLKSMDDKVVGSNKKINIVPGFETYLGNFRVIKRMLSEMGVGYSLLSDPEEVLDTPADGQFRMYAGGTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSEISGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGLVKFLLELGCEPVHILCHNGNKRWKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGKFIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILERLDEETRGMQATDYNHDLVR 5bvg D 1.60 BS04 SE D 1 N65 W428 R453 N64 W427 R452 1.18.6.1 P07329 26673079 SQQVDKIKASYPLFLDQDYKDMLAKKRDGFEEKYPQDKIDEVFQWTTTKEYQELNFQREALTVNPAKACQPLGAVLCALGFEKTMPYVHGSQGCVAYFRSYFNRHFREPVSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYKPDMIAVSTTCMAEVIGDDLNAFINNSKKEGFIPDEFPVPFAHTPSFVGSHVTGWDNMFEGIARYFTLKSMDDKVVGSNKKINIVPGFETYLGNFRVIKRMLSEMGVGYSLLSDPEEVLDTPADGQFRMYAGGTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSEISGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGLVKFLLELGCEPVHILCHNGNKRWKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGKFIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILERLDEETRGMQATDYNHDLVR 5cbr A 2.00 BS01 4ZK A 1 E10 Y13 Y58 P86 L87 T88 R93 L135 S139 T140 T171 Y187 L188 L189 E190 M193 Y217 E10 Y13 Y58 P86 L87 T88 R93 L135 S139 T140 T171 Y187 L188 L189 E190 M193 Y217 P19491 26653877 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 5cbs A 1.80 BS01 E42 A 1 Y58 P86 L87 T88 R93 L106 I108 S139 E190 D213 K215 Y217 Y58 P86 L87 T88 R93 L106 I108 S139 E190 D213 K215 Y217 P19491 26653877 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 5cc2 A 2.50 BS01 CKA A 1 E12 F15 Y58 A85 L86 T87 R92 A138 W193 D194 V197 Y222 E10 F13 Y56 A83 L84 T85 R90 A136 W191 D192 V195 Y220 Q63226 26661043 VVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWP 5cc2 A 2.50 BS02 CKA A 2 V107 L120 V139 H142 V143 Y157 M160 V192 N215 V217 V105 L118 V137 H140 V141 Y155 M158 V190 N213 V215 Q63226 26661043 VVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWP 5cc2 A 2.50 BS03 CKA A 3 V174 A179 Q182 K183 V172 A177 Q180 K181 Q63226 26661043 VVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWP 5cnq A 2.60 BS01 NUC R 1 F44 Q45 G207 G209 I210 K211 V212 F43 Q44 G186 G188 I189 K190 V191 G0RYN2 GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARGGSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPGVSTAMAKRLIRLFGFTAHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPPTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGGIPGCGIKVACQAAKAGFGKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIKVLAPGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS 5cnq A 2.60 BS02 NUC H 1 G2 K4 Y7 E140 D141 T257 K258 H259 K260 A261 G1 K3 Y6 E127 D128 T228 K229 H230 K231 A232 G0RYN2 GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARGGSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPGVSTAMAKRLIRLFGFTAHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPPTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGGIPGCGIKVACQAAKAGFGKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIKVLAPGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS 5cnq A 2.60 BS03 MN A 1 E122 E140 E109 E127 G0RYN2 GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARGGSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPGVSTAMAKRLIRLFGFTAHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPPTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGGIPGCGIKVACQAAKAGFGKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIKVLAPGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS 5cnq A 2.60 BS04 MN A 2 D141 D143 D128 D130 G0RYN2 GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARGGSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPGVSTAMAKRLIRLFGFTAHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPPTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGGIPGCGIKVACQAAKAGFGKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIKVLAPGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS 5cw1 A 1.45 BS01 PYZ A 1 S132 L133 G134 A158 G160 S224 S132 L133 G134 A158 G160 S224 3.4.21.64 P06873 AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNGSGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQSSGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLDIFGPGTDILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACRYIADTANKGDLSNIPFGTVNLLAYNNYQA 5cw1 A 1.45 BS03 PYZ A 3 Y104 I107 L133 G134 G135 G136 S170 Y104 I107 L133 G134 G135 G136 S170 3.4.21.64 P06873 AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFEGRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNGSGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQSSGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLDIFGPGTDILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACRYIADTANKGDLSNIPFGTVNLLAYNNYQA 5cxr A 2.00 BS03 MN A 3 P68 H74 P73 H79 M9QLS3 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5cxr A 2.00 BS04 BYZ A 1 S149 F150 T151 G152 K172 L175 F176 S154 F155 T156 G157 K177 L180 F181 M9QLS3 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5cxr A 2.00 BS05 BYZ A 2 L16 K19 A20 E23 E80 G81 R82 D83 L21 K24 A25 E28 E85 G86 R87 D88 M9QLS3 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5cxr A 2.00 BS06 BYZ A 3 P-3 G-1 R185 P2 G4 R190 M9QLS3 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5cxr A 2.00 BS07 BYZ A 4 A20 Y24 E26 I38 A25 Y29 E31 I43 M9QLS3 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5cxr A 2.00 BS08 BYZ A 5 M12 I13 E43 F46 D50 M17 I18 E48 F51 D55 M9QLS3 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER 5cym A 2.10 BS01 T27 A 1 P95 L100 K101 K103 V179 Y181 Y188 F227 W229 L234 H235 P236 Y318 P91 L96 K97 K99 V175 Y177 Y184 F223 W225 L230 H231 P232 Y314 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNDKLSA 5cym A 2.10 BS02 PYZ A 1 T165 L168 E169 A172 T161 L164 E165 A168 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNDKLSA 5cym A 2.10 BS03 PYZ A 2 K20 V21 P55 N57 K22 V23 P57 N59 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNDKLSA 5cym B 2.10 BS01 PYZ B 1 Y232 Q373 K374 T377 Q407 Y212 Q353 K354 T357 Q387 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cym B 2.10 BS02 PYZ B 2 V75 D76 F77 R78 G152 M184 T409 W410 I411 V71 D72 F73 R74 G141 M173 T389 W390 I391 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cym B 2.10 BS03 PYZ B 3 P247 K249 W252 D256 K259 L260 K263 P227 K229 W232 D236 K239 L240 K243 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cym B 2.10 BS04 PYZ B 4 Y232 L234 W239 K374 T377 E378 Y212 L214 W219 K354 T357 E358 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq A 2.15 BS02 BYZ A 1 I5 A114 S117 V118 F160 S163 M164 I167 L214 I7 A116 S119 V120 F162 S165 M166 I169 L216 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS03 BYZ A 2 T165 L168 E169 A172 I180 T167 L170 E171 A174 I182 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS04 BYZ A 3 G93 P95 Y181 G95 P97 Y183 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS05 BYZ A 4 R356 K512 S513 E514 R358 K514 S515 E516 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS06 BYZ A 5 K20 V21 P55 N57 R143 K22 V23 P57 N59 R145 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS07 BYZ A 6 L452 G453 K454 L454 G455 K456 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS08 BYZ A 7 D443 G444 A445 D445 G446 A447 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS09 BYZ A 8 Y441 D443 G456 Y457 V458 G544 N545 E546 Y443 D445 G458 Y459 V460 G546 N547 E548 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq A 2.15 BS10 BYZ B 1 I380 V381 I382 V383 2.7.7.49 P03366 MVPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNE 5cyq B 2.15 BS01 BYZ A 9 T139 P140 T135 P136 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS02 BYZ A 10 N137 P140 N133 P136 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS03 BYZ B 2 V111 A114 M164 I167 L209 W212 P225 L228 V107 A110 M160 I163 L205 W208 P212 L215 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS04 BYZ B 1 P25 L26 I31 P133 S134 I135 N137 P21 L22 I27 P129 S130 I131 N133 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS06 BYZ B 4 Y232 R358 Q373 K374 T377 Q407 Y219 R345 Q360 K361 T364 Q394 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS07 BYZ B 5 P247 K249 D256 K259 K263 P234 K236 D243 K246 K250 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS08 BYZ B 6 K65 V108 D186 Y232 Q407 A408 T409 W410 K61 V104 D182 Y219 Q394 A395 T396 W397 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5cyq B 2.15 BS09 BYZ B 7 V75 D76 F77 R78 G152 T409 W410 I411 V71 D72 F73 R74 G148 T396 W397 I398 2.7.7.49 P03366 IETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQ 5d5u B 2.91 BS01 NUC A 1 F61 K62 H63 N65 S68 R71 Q72 Y76 R117 F49 K50 H51 N53 S56 R59 Q60 Y64 R98 Q00613 SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEERDDTEFQHPCFLRGQEQLLENIKRKV 5d5v B 2.55 BS01 NUC A 1 R71 N74 R79 K80 K118 T120 R58 N61 R66 K67 K94 T96 Q00613 NVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHDDTEFQHPCFLRGQEQLLENIKRKVT 5d5v B 2.55 BS02 NUC C 1 F18 F61 K62 H63 N65 S68 R71 Q72 Y76 F5 F48 K49 H50 N52 S55 R58 Q59 Y63 Q00613 NVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHDDTEFQHPCFLRGQEQLLENIKRKVT 5d5v B 2.55 BS03 MG B 1 L25 V26 D28 T31 D32 I35 L12 V13 D15 T18 D19 I22 Q00613 NVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHDDTEFQHPCFLRGQEQLLENIKRKVT 5d5v D 2.55 BS01 NUC A 1 K62 R71 N74 K50 R59 N62 Q00613 SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGVKPERDDTEFQHPCFLRGQEQLLENIKRKVT 5d5w B 2.35 BS01 NUC A 1 F86 K87 H88 N90 S93 R96 Q97 K100 Y101 F46 K47 H48 N50 S53 R56 Q57 K60 Y61 G0SB31 SDFVRKLYKMLEDPSYHSVVRWSDDGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRPYGRDAWEFKHPEFRADRKDNLDNIRR 5d5x B 2.40 BS01 NUC A 1 H88 N90 S93 R96 Q97 R142 H48 N50 S53 R56 Q57 R98 G0SB31 SDFVRKLYKMLEDPSYHSVVRWSDDGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRHNDEPYGRDAWEFKHPEFRADRKDNLDNIRRK 5d5x B 2.40 BS02 NUC D 1 R96 N99 K100 H104 K105 K143 R56 N59 K60 H64 K65 K99 G0SB31 SDFVRKLYKMLEDPSYHSVVRWSDDGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRHNDEPYGRDAWEFKHPEFRADRKDNLDNIRRK 5d5x E 2.40 BS01 NUC A 1 R96 N99 H104 K105 R107 K143 R56 N59 H64 K65 R67 K98 G0SB31 SDFVRKLYKMLEDPSYHSVVRWSDDGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRHNSPYGRDAWEFKHPEFRADRKDNLDNIRRK 5d5x E 2.40 BS02 NUC D 1 K87 H88 N90 S93 Q97 K100 R142 K47 H48 N50 S53 Q57 K60 R97 G0SB31 SDFVRKLYKMLEDPSYHSVVRWSDDGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRHNSPYGRDAWEFKHPEFRADRKDNLDNIRRK 5diz A 3.20 BS01 ZN A 1 C281 C284 H494 C511 C249 C252 H452 C469 3.1.26.5 Q680B9 26655022 NPETNLLFNLNSCSKSKDLSAALALYDAAITSSEVRLSQQHFQTLLYLCSASITDISLQYLAIDRGFEIFDRMVSSGISPNEASVTSVARLAAAKGNGDYAFKVVKEFVSVGGVSIPRLRTYAPALLCFCEKLEAEKGYEVEEHMEAAGIALEEAEISALLKVSAATGRENKVYRYLHKLREYVGCVSEETLKIIEEWFCGEKAGEVGDDVGMLREAVLNNGGGWHGHGWVGEGKWTVKKGNVSSTGRCLSCSEQLACVDTNEVETQKFVDSLVALAMDRVVFSEFQDWLEKHGDYEAIVDGANIGLYQQNFVDGSFSLSQLESVMKELYRESGNNKWPLILLHKRRVKTLLENPTHRNLVEEWISNGVLYATPPGSNDDWYWLYAAAKLKCLLVTNDEMRDHIFELLGSTFFQKWKERHQVRYTFVKGNLKLEMPSPFSVVIQESEKGSWHFPVSCENNEESSRTWMCISRQS 5e0l A 1.31 BS01 III C 1 K9 D12 R60 N61 F62 G63 S64 Y65 V66 T67 H68 E69 T70 F73 Y75 Y77 A82 L84 G89 K7 D10 R58 N59 F60 G61 S62 Y63 V64 T65 H66 E67 T68 F71 Y73 Y75 A80 L82 G87 Q24117 26652654 DRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 5e0m A 1.65 BS01 III C 1 K9 N10 D12 R60 N61 F62 G63 S64 Y65 V66 T67 H68 F73 Y75 Y77 A82 L84 K7 N8 D10 R58 N59 F60 G61 S62 Y63 V64 T65 H66 F71 Y73 Y75 A80 L82 Q24117 26652654 DRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG 5e7t L 2.90 BS01 CA L 1 Q114 L141 Q65 L91 Q38610 VDGDFTMKKFADSYVAFFANKGSGNTVTFTAPWDCTAEVELFYHGWGYSGGEWEIGITTPSGLTQIYEATGYTNGHNQAISMPTKAIYSGLKKGLQYTFDIRDANGRGPKHPMMIVKLYRN 5eds A 2.80 BS01 5MT A 1 V803 M804 P810 W812 I831 Y867 I879 E880 I881 V882 A885 K890 M953 I963 V553 M554 P560 W562 I581 Y617 I629 E630 I631 V632 A635 K640 M700 I710 2.7.1.153,2.7.11.1 P48736 26652588 SQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEVSLWDCDRKFRVKIRGIDIPVLDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISSFNADKLTSATNPDKENSMSISILLDPIALPKHEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFL 5efq A 2.00 BS01 ADP A 1 I711 G714 T715 A732 K734 F791 E792 M794 D797 S841 N842 L844 D855 H1018 I17 G20 T21 A38 K40 F88 E89 M91 D94 S138 N139 L141 D152 H315 2.7.11.22,2.7.11.23 Q14004 IDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 5efq A 2.00 BS04 MG A 2 D837 D855 D134 D152 2.7.11.22,2.7.11.23 Q14004 IDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKR 5em5 A 2.65 BS01 5Q2 A 1 L718 V726 A743 K745 L788 M790 Q791 M793 P794 G796 L844 L22 V30 A47 K49 L88 M90 Q91 M93 P94 G96 L144 2.7.10.1 P00533 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKETSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYEEDMDDVVDADEYLIP 5em6 A 2.78 BS01 5Q3 A 1 L718 A743 K745 E762 M766 C775 M790 Q791 M793 P794 G796 L844 T854 D855 L22 A47 K49 E63 M67 C76 M91 Q92 M94 P95 G97 L145 T155 D156 2.7.10.1 P00533 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELTSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYEEDMDDVVDADEYLIP 5em7 A 2.81 BS01 5Q4 A 1 L718 A743 M790 Q791 M793 P794 F795 G796 E804 R841 N842 L844 T854 D855 L23 A48 M92 Q93 M95 P96 F97 G98 E106 R143 N144 L146 T156 D157 2.7.10.1 P00533 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKEATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYDMDDVVDADEYLIP 5em8 A 2.80 BS01 5Q4 A 1 L718 A743 T790 Q791 M793 P794 F795 G796 E804 N842 L844 T854 D855 L23 A48 T92 Q93 M95 P96 F97 G98 E106 N144 L146 T156 D157 2.7.10.1 P00533 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKEATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPDMDDVVDADEYLI 5erc A 2.05 BS01 ZN A 1 C293 C296 C317 C320 C20 C23 C44 C47 P55201 26626149 AVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRVRKTAYCDIHTPP 5erc A 2.05 BS02 ZN A 2 C276 C279 H301 C304 C3 C6 H28 C31 P55201 26626149 AVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRVRKTAYCDIHTPP 5erc A 2.05 BS05 ZN A 5 C400 C405 C444 H447 C127 C132 C161 H164 P55201 26626149 AVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRVRKTAYCDIHTPP 5eu8 A 2.45 BS01 III B 1 N25 V26 L27 H41 T47 C144 H162 H163 L164 E165 Q187 P188 S189 M190 N26 V27 L28 H42 T48 C145 H163 H164 L165 E166 Q188 P189 S190 M191 V9PIT1 26656689 SSGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRVINYENELSSVRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFTEIVSTDAFNMLAAKTGYSVEKLLECIVRLNKGFGGRTILSYGSLCDEFTPTEVIRQMYGV 5eu8 A 2.45 BS02 ZN A 1 H41 H163 D186 H42 H164 D187 V9PIT1 26656689 SSGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRVINYENELSSVRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFTEIVSTDAFNMLAAKTGYSVEKLLECIVRLNKGFGGRTILSYGSLCDEFTPTEVIRQMYGV 5euh A 2.99 BS01 C2E A 1 R409 R410 D413 T430 Q437 I438 R71 R72 D75 T92 Q99 I100 Q3K751 26670387 AATDALTGVANRRMLDQSLRHEWFRAQRSGKPLSLLMIDADHFKAFNDRHGHQAGDQALRELARVITTNVRRPADLVARYGGEEFSVILAETDSVGAQQIAEHIRAAVEQLSSVNEDQSPMTVSIGISTWTATSEISLEQLLFAADKALYQAKEGGRNRVVVAA 5euh B 2.99 BS01 C2E B 1 R409 R410 P411 R71 R72 P73 Q3K751 26670387 AATDALTGVANRRMLDQSLRHEWFRAQRSGKPLSLLMIDADHFKAFNDRHGHQAGDQALRELARVITTNVRRPADLVARYGGEEFSVILAETDSVGAQQIAEHIRAAVEQLSSVNEDQSPMTVSIGISTWTATSEISLEQLLFAADKALYQAKEGGRNRVVVAA 5euh C 2.99 BS01 C2E C 1 H359 F362 R366 H20 F23 R27 Q3K751 26670387 ATDALTGVANRRMLDQSLRHEWFRAQRSGKPLSLLMIDADHRHGHQAGDQALRELARVITTNVRRPADLVARYGGEEFSVILAETDSVGAQQIAEHIRAAVSIGISTWTATSEISLEQLLFAADKALYQAKEGGRNRVVVAA 5exd B 2.50 BS01 SF4 B 1 P254 C271 P272 I276 F285 C290 K291 G292 C293 G294 L295 C296 P225 C242 P243 I247 F256 C261 K262 G263 C264 G265 L266 C267 1.2.7.10 Q2RI40 KDLFAEPNLKQITVWARGVVMNKDARDIVVALTEAAAKEGKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAEGIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPPAVSATELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD 5exd B 2.50 BS02 SF4 B 2 C261 T262 E263 C264 Y265 C267 P283 C300 S302 L305 C232 T233 E234 C235 Y236 C238 P254 C271 S273 L276 1.2.7.10 Q2RI40 KDLFAEPNLKQITVWARGVVMNKDARDIVVALTEAAAKEGKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAEGIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPPAVSATELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD 5exd C 2.50 BS01 SF4 C 1 T23 C24 C27 P29 C52 N138 A142 C225 P226 K227 T23 C24 C27 P29 C52 N138 A142 C225 P226 K227 1.2.7.10 Q2RI42 MLDRIASIKKAPDEEYYVPGHRTCAGCGPALTYRLVAKAAGPNTIFIGPTGCMYVANTSYGCGPWRVPWIHAQITNGGAVASGIEAAYKAMIRKKKTDAEFPNIIVMAGDGGAVDIGLQALSAMLYRGHDVLFICYDNESYANTGIQTSPTTPYGANTTFTPPGEVVPEGKKLFPKDNPKVIAHGHPELKYVATASIGWPVDLMNKVRKGLNQEGPAYIHIHAPCPKGWQFPADKTIEMAKLAVQTGMFQLYEYENGEYKLSVKVDKRKPVSEYMKLQKRFAHLKPEHIAKMQAFVDARCAEVGITVPVVAS 5exd D 2.50 BS01 O2T F 1 Y28 P29 I30 R31 E59 V83 R109 D116 Y27 P28 I29 R30 E58 V82 R108 D115 1.2.7.10 Q2RI41 GKVRNISGCVAVAHGVRLADVDVICSYPIRPYTGIMSELARMVADGELDAEFVHGEGEHAQLSVVYGASAAGARVFTGSSGVGVTYAMEVYSPISGERLPVQMAIADRTLDPPGDFGEEHTDAECCRDQGWIQGWASTPQEALDNTLIYYRVGEDQRVLLPQYACLDGYFVSHILGPVDIPDEAQVKEFLPPYKNHHVLDPRKPQIIGPQIEPAMGPPLQYQRYQAVKGVHKVLEEACDEFARIFGRKYDPYLDEYLTDDAEVIIFGQGAHMETAKAVARRLRNLGEKVGVARLRTFRPFPTEQIKERLSKFKAIGVLDVSANFGISCSGGVLLSELRAALYDYGDKVKTVGFVAGLGGEVVTHDEFYRMFQKLKEIAKTGKVEQTSYWIPFEL 5exd E 2.50 BS01 SF4 E 1 P254 C271 P272 I276 F285 C290 K291 G292 C293 G294 L295 C296 P234 C251 P252 I256 F265 C270 K271 G272 C273 G274 L275 C276 1.2.7.10 Q2RI40 LFAEPNLKQITVWARGVVMNKDARDIVVALTEAAKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAEAVMTLSGAEGATDATGIGAGIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPPTELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD 5exd E 2.50 BS02 SF4 E 2 I256 C261 T262 E263 C264 Y265 T266 C267 P283 C300 P301 S302 A304 L305 I236 C241 T242 E243 C244 Y245 T246 C247 P263 C280 P281 S282 A284 L285 1.2.7.10 Q2RI40 LFAEPNLKQITVWARGVVMNKDARDIVVALTEAAKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAEAVMTLSGAEGATDATGIGAGIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPPTELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD 5exd F 2.50 BS02 O2T F 1 T50 G51 C52 I74 D110 G111 G112 Y136 N138 S140 Y141 A142 N143 T144 T50 G51 C52 I74 D110 G111 G112 Y136 N138 S140 Y141 A142 N143 T144 1.2.7.10 Q2RI42 MLDRIASIKKAPDEEYYVPGHRTCAGCGPALTYRLVAKAAGPNTIFIGPTGCMYVANTSYGCGPWRVPWIHAQITNGGAVASGIEAAYKAMIRKKKTDAEFPNIIVMAGDGGAVDIGLQALSAMLYRGHDVLFICYDNESYANTGIQTSPTTPYGANTTFTPPGEVVPEGKKLFPKDNPKVIAHGHPELKYVATASIGWPVDLMNKVRKGLNQEGPAYIHIHAPCPKGWQFPADKTIEMAKLAVQTGMFQLYEYENGEYKLSVKVDKRKPVSEYMKLQKRFAHLKPEHIAKMQAFVDARCAEVGITVPVV 5exd H 2.50 BS02 SF4 H 2 I256 C261 T262 E263 C264 Y265 T266 C267 P283 C300 P301 S302 L305 I232 C237 T238 E239 C240 Y241 T242 C243 P259 C276 P277 S278 L281 1.2.7.10 Q2RI40 DLFAEPNLKQITVWARGVVMNKDARDIVVALTEAAAKEGKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAGIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPPHEAVEEAAVSATELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD 5exd J 2.50 BS01 TPP L 1 P29 I30 E59 V83 P28 I29 E58 V82 1.2.7.10 Q2RI41 GKVRNISGCVAVAHGVRLADVDVICSYPIRPYTGIMSELARMVADGELDAEFVHGEGEHAQLSVVYGASAAGARVFTGSSGVGVTYAMEVYSPISGERLPVQMAIADRTLDPPGDFGEEHTDAECCRDQGWIQGWASTPQEALDNTLIYYRVGEDQRVLLPQYACLDGYFVSHILGPVDIPDEAQVKEFLPPYKNHHVLDPRKPQIIGPQIEPAMGPPLQYQRYQAVKGVHKVLEEACDEFARIFGRKYDPYLDEYLTDDAEVIIFGQGAHMETAKAVARRLRNLGEKVGVARLRTFRPFPTEQIKERLSKFKAIGVLDVSANFGISCSGGVLLSELRAALYDYGDKVKTVGFVAGLGGEVVTHDEFYRMFQKLKEIAKTGKVEQTSYWIPFEL 5exd K 2.50 BS01 SF4 K 1 C271 P272 D273 C275 I276 F285 C290 K291 G292 C293 G294 L295 C296 C236 P237 D238 C240 I241 F250 C255 K256 G257 C258 G259 L260 C261 1.2.7.10 Q2RI40 LFAEPNLKQITVWARGVVMNKDARDIVVALTEAAAKEGKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPVSATELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD 5exe A 1.88 BS01 5SR C 1 Y28 P29 I30 E59 V83 R109 F117 Y27 P28 I29 E58 V82 R108 F116 1.2.7.10 Q2RI41 GKVRNISGCVAVAHGVRLADVDVICSYPIRPYTGIMSELARMVADGELDAEFVHGEGEHAQLSVVYGASAAGARVFTGSSGVGVTYAMEVYSPISGERLPVQMAIADRTLDPPGDFGEEHTDAECCRDQGWIQGWASTPQEALDNTLIYYRVGEDQRVLLPQYACLDGYFVSHILGPVDIPDEAQVKEFLPPYKNHHVLDPRKPQIIGPQIEPAMGPPLQYQRYQAVKGVHKVLEEACDEFARIFGRKYDPYLDEYLTDDAEVIIFGQGAHMETAKAVARRLRNLGEKVGVARLRTFRPFPTEQIKERLSKFKAIGVLDVSANFGISCSGGVLLSELRAALYDYGDKVKTVGFVAGLGGEVVTHDEFYRMFQKLKEIAKTGKVEQTSYWIPFEL 5exe C 1.88 BS01 SF4 C 1 C24 C27 P29 C52 N138 C225 P226 K227 C24 C27 P29 C52 N138 C225 P226 K227 1.2.7.10 Q2RI42 MLDRIASIKKAPDEEYYVPGHRTCAGCGPALTYRLVAKAAGPNTIFIGPTGCMYVANTSYGCGPWRVPWIHAQITNGGAVASGIEAAYKAMIRKKKTDAEFPNIIVMAGDGGAVDIGLQALSAMLYRGHDVLFICYDNESYANTGIQTSPTTPYGANTTFTPPGEVVPEGKKLFPKDNPKVIAHGHPELKYVATASIGWPVDLMNKVRKGLNQEGPAYIHIHAPCPKGWQFPADKTIEMAKLAVQTGMFQLYEYENGEYKLSVKVDKRKPVSEYMKLQKRFAHLKPEHIAKMQAFVDARCAEVGITVPVVASNA 5exe C 1.88 BS02 5SR C 1 T50 G51 C52 V55 I74 G109 D110 G111 G112 Y136 N138 S140 Y141 A142 N143 T144 T50 G51 C52 V55 I74 G109 D110 G111 G112 Y136 N138 S140 Y141 A142 N143 T144 1.2.7.10 Q2RI42 MLDRIASIKKAPDEEYYVPGHRTCAGCGPALTYRLVAKAAGPNTIFIGPTGCMYVANTSYGCGPWRVPWIHAQITNGGAVASGIEAAYKAMIRKKKTDAEFPNIIVMAGDGGAVDIGLQALSAMLYRGHDVLFICYDNESYANTGIQTSPTTPYGANTTFTPPGEVVPEGKKLFPKDNPKVIAHGHPELKYVATASIGWPVDLMNKVRKGLNQEGPAYIHIHAPCPKGWQFPADKTIEMAKLAVQTGMFQLYEYENGEYKLSVKVDKRKPVSEYMKLQKRFAHLKPEHIAKMQAFVDARCAEVGITVPVVASNA 5exe C 1.88 BS04 MG C 2 D130 L211 Q213 D130 L211 Q213 1.2.7.10 Q2RI42 MLDRIASIKKAPDEEYYVPGHRTCAGCGPALTYRLVAKAAGPNTIFIGPTGCMYVANTSYGCGPWRVPWIHAQITNGGAVASGIEAAYKAMIRKKKTDAEFPNIIVMAGDGGAVDIGLQALSAMLYRGHDVLFICYDNESYANTGIQTSPTTPYGANTTFTPPGEVVPEGKKLFPKDNPKVIAHGHPELKYVATASIGWPVDLMNKVRKGLNQEGPAYIHIHAPCPKGWQFPADKTIEMAKLAVQTGMFQLYEYENGEYKLSVKVDKRKPVSEYMKLQKRFAHLKPEHIAKMQAFVDARCAEVGITVPVVASNA 5exe D 1.88 BS01 5SR F 1 Y28 P29 I30 E59 V83 R109 D116 Y27 P28 I29 E58 V82 R108 D115 1.2.7.10 Q2RI41 GKVRNISGCVAVAHGVRLADVDVICSYPIRPYTGIMSELARMVADGELDAEFVHGEGEHAQLSVVYGASAAGARVFTGSSGVGVTYAMEVYSPISGERLPVQMAIADRTLDPPGDFGEEHTDAECCRDQGWIQGWASTPQEALDNTLIYYRVGEDQRVLLPQYACLDGYFVSHILGPVDIPDEAQVKEFLPPYKNHHVLDPRKPQIIGPQIEPAMGPPLQYQRYQAVKGVHKVLEEACDEFARIFGRKYDPYLDEYLTDDAEVIIFGQGAHMETAKAVARRLRNLGEKVGVARLRTFRPFPTEQIKERLSKFKAIGVLDVSANFGISCSGGVLLSELRAALYDYGDKVKTVGFVAGLGGEVVTHDEFYRMFQKLKEIAKTGKVEQTSYWIPFEL 5exe F 1.88 BS01 SF4 F 1 T23 C24 C27 P29 C52 N138 C225 P226 K227 T23 C24 C27 P29 C52 N138 C225 P226 K227 1.2.7.10 Q2RI42 MLDRIASIKKAPDEEYYVPGHRTCAGCGPALTYRLVAKAAGPNTIFIGPTGCMYVANTSYGCGPWRVPWIHAQITNGGAVASGIEAAYKAMIRKKKTDAEFPNIIVMAGDGGAVDIGLQALSAMLYRGHDVLFICYDNESYANTGIQTSPTTPYGANTTFTPPGEVVPEGKKLFPKDNPKVIAHGHPELKYVATASIGWPVDLMNKVRKGLNQEGPAYIHIHAPCPKGWQFPADKTIEMAKLAVQTGMFQLYEYENGEYKLSVKVDKRKPVSEYMKLQKRFAHLKPEHIAKMQAFVDARCAEVGITVPVVASN 5f2k A 1.60 BS01 SAH A 1 M19 Y24 L35 G64 A66 N70 D98 V99 S133 F134 Y135 S150 W151 A152 W155 M9 Y14 L25 G54 A56 N60 D88 V89 S123 F124 Y125 S140 W141 A142 W145 B2HHT4 26526103 SVVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVPLPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVPDNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSSWAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRGRELCPGGRLVVLTMALDEHGHFGYRPMNDALVAALNDQVRDGLLRPEELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQSDGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADRLASQPEPMRIPLASLVLAKRA 5f2k A 1.60 BS02 OCA A 1 Y24 Q31 W151 Q154 W155 M214 F222 F311 A315 L316 Y14 Q21 W141 Q144 W145 M204 F212 F301 A305 L306 B2HHT4 26526103 SVVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVPLPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVPDNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSSWAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRGRELCPGGRLVVLTMALDEHGHFGYRPMNDALVAALNDQVRDGLLRPEELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQSDGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADRLASQPEPMRIPLASLVLAKRA 5f2k B 1.60 BS02 OCA B 1 Y24 Q31 W151 Q154 W155 M214 F222 F311 L316 Y13 Q20 W140 Q143 W144 M203 F211 F300 L305 B2HHT4 26526103 VVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVPLPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVPDNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSSWAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRGRELCPGGRLVVLTMALDEHGHFGYRPMNDALVAALNDQVRDGLLRPEELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQSDGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADRLASQPEPMRIPLASLVLAKR 5f2n A 1.90 BS02 5UF A 1 Y24 Q31 Q154 W155 M214 N228 F311 A315 L316 Y14 Q21 Q144 W145 M204 N218 F301 A305 L306 B2HHT4 26526103 SVVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVPLPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVPDNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSSWAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRGRELCPGGRLVVLTMALDEHGHFGYRPMNDALVAALNDQVRDGLLRPEELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQSDGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADRLASQPEPMRIPLASLVLAKR 5f2n B 1.90 BS02 5UF B 1 Y24 Q31 W151 Q154 W155 M214 F222 Y224 N228 F311 A315 L316 Y13 Q20 W140 Q143 W144 M203 F211 Y213 N217 F300 A304 L305 B2HHT4 26526103 VVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVPLPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVPDNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSSWAIQWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRGRELCPGGRLVVLTMALDEHGHFGYRPMNDALVAALNDQVRDGLLRPEELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQSDGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADRLASQPEPMRIPLASLVLAKR 5f2o A 1.85 BS02 5UF A 1 Y24 Q31 W151 W155 M214 N228 F311 A315 L316 Y14 Q21 W141 W145 M204 N218 F301 A305 L306 B2HHT4 26526103 SVVVRPAPMESATYSQSSRLQAAGLSPAITLFEKAAQTVPLPDAPQPVVIADYGVATGHNSLKPMMAAINALRRRIREDRAIMVAHTDVPDNDFTALFRTLADDPDSYLHHDSASFASAVGRSFYTQILPSNTVSLGWSSWAIAWLSRIPAGAPELTDHVQVAYSKDERARAAYAHQAATDWQDFLAFRGRELCPGGRLVVLTMALDEHGHFGYRPMNDALVAALNDQVRDGLLRPEELRRMAIPVVARAEKDLRAPFAPRGWFEGLTIEQLDVFNAEDRFWAAFQSDGDAESFGAQWAGFARAALFPTLAAALDCGTGDPRATAFIEQLEASVADRLASQPEPMRIPLASLVLAKRA 5f47 A 1.50 BS01 TRE A 1 F35 Y90 Q126 D128 D131 F29 Y84 Q120 D122 D125 A0A059WZ16 IDNFLKIERLAENDLPKFIQLIRLFEAVFEMKNFSIPDSEHLQKLLNQNNFYVFVALLENKIVGGLTSYVLEQYYSEKPLAYIYDLAVDTNWQRQGIGKKLITATNQFYTEKGFEEVFVQADKVDDYALDFYRSTKPTAEEQVVHFYYTLK 5f48 A 1.95 BS02 COA B 1 V34 F35 L92 A93 V94 Q99 R100 Q101 G102 I103 G104 K105 D131 Y133 D136 F137 S140 V27 F28 L85 A86 V87 Q92 R93 Q94 G95 I96 G97 K98 D124 Y126 D129 F130 S133 A0A059WZ16 DNFLKIERLAENDLPKFIQLIRLFEAVFEMKNFSIPDSEHLQKLLNQNNFYVFVALLENKIVGGLTSYVLEQYYSEKPLAYIYDLAVDTNWQRQGIGKKLITATNQFYTEKGFEEVFVQADKVDDYALDFYRSTKPTAEEQVVHFYYTLK 5f48 B 1.95 BS01 COA B 2 V34 F35 L92 A93 V94 Q99 R100 Q101 G102 I103 G104 K105 Y133 F137 S140 V28 F29 L86 A87 V88 Q93 R94 Q95 G96 I97 G98 K99 Y127 F131 S134 A0A059WZ16 IDNFLKIERLAENDLPKFIQLIRLFEAVFEMKNFSIPDSEHLQKLLNQNNFYVFVALLENKIVGGLTSYVLEQYYSEKPLAYIYDLAVDTNWQRQGIGKKLITATNQFYTEKGFEEVFVQADKVDDYALDFYRSTKPTAEEQVVHFYYTLK 5f5c A 1.88 BS02 5V3 A 1 Y136 Y179 Y181 F189 H192 E194 K210 W212 H280 A292 N294 Y126 Y169 Y171 F179 H182 E184 K200 W202 H270 A282 N284 1.14.11.- Q6B0I6 AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQ 5f5i A 2.63 BS02 5V1 A 1 Y132 G170 Y175 Y177 F185 H188 E190 K206 W208 H276 S288 N290 Y129 G167 Y172 Y174 F182 H185 E187 K203 W205 H273 S285 N287 1.14.11.- O75164 ESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAE 5f5i B 2.63 BS02 5V1 B 1 Y132 Y175 Y177 F185 H188 E190 K206 W208 H276 S288 T289 N290 Y125 Y162 Y164 F172 H175 E177 K193 W195 H263 S275 T276 N277 1.14.11.- O75164 LNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEF 5f5x A 2.01 BS01 AMP A 1 I29 I88 G89 A116 T140 R179 L180 E181 W182 E246 K279 H313 I30 I89 G90 A117 T141 R180 L181 E182 W183 E247 K280 H314 Q734X3 AMLIKPKRLQAGDIVATVSPSWGGAGDSEIRWRYEQGVKRLEEVFGLTVVPMPNSLKGSEFIYNNPQARAEDLMTAFQDTRVKAIIANIGGQDSIRLLPYIDFNAIRENPKIFMGYADVTISHLFCHKAGLSSFYGPAILTDFAENVEMDPYTVEMVNRTLFSNEMIGEIQPAPEWTSERLEWIEINKDTRRTMQQNNGYELLQGSTTVQGRLIGGCIEVLEFAKGTELWPEKKHWEDSILFFETSEDHPEPSYIKYWLRNYAAQGILQKAKGIIFGKPKDEMYYEEYKHEILQVMKEHNLEDLPILYNLNFGHTEPKFILPYGSMAEIDCENGSFSILESGVE 5f5x B 2.01 BS01 AMP B 1 I29 I88 G89 G90 A116 R179 L180 E181 W182 E246 K279 H313 I30 I89 G90 G91 A117 R180 L181 E182 W183 E247 K280 H314 Q734X3 AMLIKPKRLQAGDIVATVSPSWGGAGDSEIRWRYEQGVKRLEEVFGLTVVPMPNSLKGSEFIYNNPQARAEDLMTAFQDTRVKAIIANIGGQDSIRLLPYIDFNAIRENPKIFMGYADVTISHLFCHKAGLSSFYGPAILTDFAENVEMDPYTVEMVNRTLFSNEMIGEIQPAPEWTSERLEWIEINKDTRRTMQQNNGYELLQGSTTVQGRLIGGCIEVLEFAKGTELWPEKKHWEDSILFFETSEDHPEPSYIKYWLRNYAAQGILQKAKGIIFGKPKDEMYYEEYKHEILQVMKEHNLEDLPILYNLNFGHTEPKFILPYGSMAEIDCENGSFSILESGVE 5f7s A 2.30 BS01 CA A 1 W430 D467 W401 D438 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEATPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVG 5f7s A 2.30 BS02 CA A 2 E376 E379 E347 E350 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEATPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVG 5f7s B 2.30 BS02 CA B 2 D467 R516 D439 R488 X4QP62 MITHRPRGIEHPYARSLDQLYPAIPIAGQSLTIGATTSGPCSRMRCFVLWPEHEQVFDMSPVNGWQTSIPHLPDQDATYYFEALTLDGRTETSESFPLTPSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVVGFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRTWYDVAATVSDRILIEVDLGFEAEKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVG 5fbt A 2.70 BS01 5WQ A 1 V333 Y351 T354 T355 P356 A357 V368 M383 L387 L478 F479 M673 V249 Y267 T270 T271 P272 A273 V284 M299 L303 L380 F381 M575 KPYVLKFQEISEALVGGKGMNLGACSNIEGVHVPAGFCLTTEAYKEFTQLLQRLAIREISETIRTLIQHTQIPSEIASYMDATMPFAVLLQHISMCWASLFTEVQLAVVIQQMISPEASGILFTADPITSNRKSLSIDASFGLGESGLVSADSYTVRENTITNKIIATKKLAETRILEKSQQTKQTLTDQQIIQLAKLGRKIEAYFGKPQDIEWCLAEGAFYIVQSRPITTLYPIPEVNEPGNRVYISVAHQQMMTDAMKPLGLSFYLMTTPATMYTAGGRLFVDITQSLSAKVSRDMMVNSLGQSDPLIKDALLTVINKKGFLPPLPTVRSIPDSSSVFELVRNSENSIKHLKQSIETKSGSDLFDFIVEDLEELKRVLFNPTSIDAIMAGMDASAWLNEHIYQWLGEKNVADKLSESAPNNITSQMGLELLDVADVIRPYPAVRAYLEQTKNPDFMNELATLEGGAETKKALEDYLQKYGMRCAGEIDLTKTRWIENPLTLIPLILSNIKNFDSSASMHKFAQGEKEAFHKEQEILRRLQELPDGEQKAMETKEKIDILRHFIGYREYPKYGMINRYFIYKLALLRAGEQLVKDGILQEHEDIYFLYFEELREVVRTGQVDYELINARKRDFATFEKLTPPRILTSDGEMINGEYKRENLPKDAILGLPVSSGTVEGRARVILEMEKADLEDGDILVTAYTDPSWTPAFVSIKGLVTEVGGLMTHGAVIAREYGLPAVVGVENATTIIKDGQQIRINGTEGYIEILD 5fbu A 2.85 BS01 5WP A 1 I331 V333 Q336 Q337 Y351 T354 T355 P356 V368 L387 L478 F479 M488 M491 R666 K670 M673 H825 I211 V213 Q216 Q217 Y231 T234 T235 P236 V248 L267 L344 F345 M354 M357 R532 K536 M539 H691 KPYVLKFQEIRPGGKGMNLGACSNIEGVHVPAEAYKRTLEFTQLLQRLSSAIREISETIRTLIQHTQIPSEIASYMDATLLDVGKDALLQHISMCWASLFTERAIIHRKVQLAVVIQQMISPSGILFTADPITSNRKSLSIDDSYTVRENTITNKIIDQQIIQLAKLGRKIEAYFGKPQDIEWCFYIVQSRPITTLYPIPEVNEPGNRVYISVAHQQMMTDAMKPLGLSFYLMTTPATMYTAGGRLFVDITQSLSAKVSRDMMVNSLGQSDPLIKDALLTVINKKGFLPPLPTVRSIPDSSSVFELVRNSENSIKHLKQSIETKSGSDLFDFIVEDLEELKRVLFNPTSIDAIMAGMDASAWLNEHIYQWLGEKNVADKLSESAPNNITSQMGLELLDVADVIRPYPAVRAYLEQTKNPDFMNELATLEGGAETKKALEDYLQKYGMRCAGEIDLTKTRWIENPLTLIPLILSNIKNFDSSASMHKFAQGEKEAFHKEQEILRRLQELPDGEQKAMETKEKIDILRHFIGYREYPKYGMINRYFIYKLALLRAGEQLVKDGILQEHEDIYFLYFEELREVVRTGQVDYELINARKRDFATFEKLTPPRILTSDGEMINGEYKRENLPKDAILGLPVSSGTVEGRARVILEMEKADLEDGDILVTAYTDPSWTPAFVSIKGLVTEVGGLMTHGAVIAREYGLPAVVGVENATTIIKDGQQIRINGTEGYIEILD 5fcd A 2.10 BS01 III D 1 G34 Y37 H203 M205 V259 G6 Y9 H175 M177 V220 Q83Y56 DNTPPGAEYTIDYWIKHGCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKYYVADACDLPFEDNTFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKISDKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIFNRQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK 5fcd B 2.10 BS01 III E 1 G34 Y37 F156 H203 M205 G5 Y8 F127 H174 M176 Q83Y56 NTPPGAEYTIDYWIKHGCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKYYVADACDLPFEDNTFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKISDKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIFNRNQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK 5fd8 A 2.05 BS01 A5A A 1 I23 L83 G84 Y110 S111 H133 D171 W173 Y174 D230 H299 I25 L85 G86 Y112 S113 H135 D173 W175 Y176 D232 H301 Q81JT5 NAMLPTKLKKGDEIRVISPSCSLSIVSTENRRLAVKRLTELGFHVTFSTHAEEIDRFASSSISSRVQDLHEAFRDPNVKAILTTLGGYNSNGLLKYLDYDLIRENPKFFCGYSDITALNNAIYTKTGLVTYSGPHFSSFGMEKGLEYTTDYFLQCLTSNKPIEVLPSETWSDDSWYIDQENRKFIKNEGYVSIHEGEATGDIIGGNMSTLNLLQGTSYMPNLKDKILFLEEDSLTGTSTLKTFDRYLHSLMQQQNFKHVKGIVIGKMQKGAECTIEDIQEMIASKPELAHIPIIANASFGHTTPIFTFPIGGRATIISSKEKTSITILTH 5fd8 B 2.05 BS01 A5A B 1 C19 I23 L83 G84 G85 Y86 Y110 S111 H133 D171 W173 Y174 H299 C21 I25 L85 G86 G87 Y88 Y112 S113 H135 D173 W175 Y176 H301 Q81JT5 NAMLPTKLKKGDEIRVISPSCSLSIVSTENRRLAVKRLTELGFHVTFSTHAEEIDRFASSSISSRVQDLHEAFRDPNVKAILTTLGGYNSNGLLKYLDYDLIRENPKFFCGYSDITALNNAIYTKTGLVTYSGPHFSSFGMEKGLEYTTDYFLQCLTSNKPIEVLPSETWSDDSWYIDQENRKFIKNEGYVSIHEGEATGDIIGGNMSTLNLLQGTSYMPNLKDKILFLEEDSLTGTSTLKTFDRYLHSLMQQQNFKHVKGIVIGKMQKGAECTIEDIQEMIASKPELAHIPIIANASFGHTTPIFTFPIGGRATIISSKEKTSITILTH 5fdd A 2.51 BS01 4P8 A 1 Y29 H46 E65 E104 Y115 K119 Y29 H46 E65 E104 Y115 K119 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5fde A 2.15 BS03 4P9 A 1 E31 K34 A37 R124 F150 F191 S194 E195 E36 K39 A42 R109 F135 F176 S179 E180 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5fdg A 2.10 BS03 0N8 A 1 Y29 H46 E65 L91 D93 E104 I105 K119 Y29 H46 E65 L91 D93 E104 I105 K119 P03433 GPLGSMEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDASKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSER 5ffv A 1.30 BS01 III C 1 G650 I652 V657 V662 D664 H668 C704 Y707 N708 F714 G22 I24 V29 V34 D36 H40 C76 Y79 N80 F86 P55201 QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5ffv B 1.30 BS01 III D 1 G650 I652 V657 D664 H668 C704 Y707 N708 I713 F714 G21 I23 V28 D35 H39 C75 Y78 N79 I84 F85 P55201 LTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAE 5ffw A 1.50 BS01 III C 1 I652 V657 P663 D664 H668 C704 K706 Y707 N708 I713 F714 I23 V28 P34 D35 H39 C75 K77 Y78 N79 I84 F85 P55201 LTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5ffw B 1.50 BS01 III C 1 V657 E661 V662 C704 N708 F714 V29 E33 V34 C76 N80 F86 P55201 QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5ffy A 1.55 BS01 5XD A 1 I652 F653 V657 P658 E661 V662 Y707 N708 F714 I24 F25 V29 P30 E33 V34 Y79 N80 F86 P55201 QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5fg5 A 1.50 BS01 5XF A 1 I652 F653 E655 V657 P658 E661 V662 Y707 N708 F714 I27 F28 E30 V32 P33 E36 V37 Y82 N83 F89 P55201 MEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 5fg5 B 1.50 BS01 5XF B 1 N651 I652 F653 E655 V657 P658 E661 V662 C704 N708 F714 N23 I24 F25 E27 V29 P30 E33 V34 C76 N80 F86 P55201 QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQA 5flc B 5.90 BS01 RAP C 1 E2032 S2035 R2036 F2039 G2040 W2101 Y2105 F2108 E588 S591 R592 F595 G596 W657 Y661 F664 2.7.11.1 YAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW 5fn1 A 3.90 BS01 NUC B 1 T50 S51 Q90 S92 K93 S94 T122 R124 N147 D163 H192 K196 L200 Q203 T30 S31 Q70 S72 K73 S74 T102 R104 N127 D143 H172 K176 L180 Q183 26673077 GAKAPSDFSNPNTAPSLSDLKKVKYVSTVTSVATPAEIEALGKIFTAMGLAANETGPAMWDLARAYADVQSSKSAQLIGATPSNPALSRRALAAQFDRINITPRQFCMYFAKVVWNILLDSNIPPANWAKLGYQEDTKFAAFDFFDGVTNPASLQPADGLIRQPNEKELAAHSVAKYGALARQKISTGNYITTLGEVTRGHMGGANTMYAIDAPPEL