2n8a A BS01 NUC B 1 K15 S16 R18 A19 S20 K22 R34 F44 V48 K119 S120 R122 S123 T124 K134 R138 Q150 L151 I154 W157 K15 S16 R18 A19 S20 K22 R34 F44 V48 K119 S120 R122 S123 T124 K134 R138 Q150 L151 I154 W157 2.4.2.30 P09874 MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVD 2n8a A BS02 ZN A 1 C21 C24 H53 C56 C21 C24 H53 C56 2.4.2.30 P09874 MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVD 4rsn A 2.70 BS01 HEM A 1 K69 L86 V87 W96 I153 F261 A264 G265 T268 T269 L272 A328 F331 P392 F393 G394 R398 C400 P401 G402 F405 A406 K74 L91 V92 W101 I158 F266 A269 G270 T273 T274 L277 A333 F336 P397 F398 G399 R403 C405 P406 G407 F410 A411 1.14.14.1 P14779 RGSHMTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGLVTRFLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHVTTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVDMVLNEALRLWPTAPAFSLYAKEDTVLGGKYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACPGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4rsy A 1.93 BS01 B3N A 1 Q136 A137 Y267 G269 E271 H295 E296 H299 W311 F314 E318 V367 P374 A377 Y378 Y383 Q133 A134 Y264 G266 E268 H292 E293 H296 W308 F311 E315 V364 P371 A374 Y375 Y380 3.3.2.6 P09960 VDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 4rx5 A 1.36 BS01 3YO A 1 L408 T410 G411 F413 V416 A428 K430 Y476 M477 A478 G480 N526 L528 D539 V546 L15 T17 G18 F20 V23 A35 K37 Y83 M84 A85 G87 N133 L135 D146 V153 2.7.10.2 Q06187 SWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEN 4wio A 3.15 BS01 GLN A 1 G58 Y60 A89 Q93 N169 H170 N171 D172 H208 G52 Y54 A83 Q87 N158 H159 N160 D161 H197 6.3.5.2 Q8IJR9 DKILVLNFGSQYFHLIVKRLNNIKIFSETKDYGVELKDIKDMNIKGVILSGGPYSVTEAGSPHLKKEVFEYFLEKKIPIFGIAYGMQEIAVQMNGEVKKSKTSEYGCTDVNILRNDNINNITYCRNFSSAMDLYSNYKLMNECLFENIKSDITTVWMNHNDEVTKIPENFYLVSSSENCLICSIYNKEYNIYGVQYHPEVYESLDGELMFYNFAYNICKCKKQFDPIRYHELELKNIEKYKHDHYVIAAMSGGIDSTVAAAYTHKIFKERFFGIFIDNGLLRKNEAENVYTFLKSTFPDMNITKIDASENFLSNLQGVTDPEQKRKIIGKLFIEEFEKAVNNIDIDINKTFLLQGTLYPDIIESKCSKNLSDTIKTHHNLKFKLFEPFKYLFKDDVKTLSRELNLPEEITNRHPFPGPGLAIRVIGEINKHKLNILREVDDIFINDLKQYGLYNQISQAFAVLLSYDYVCVLRAVKTSSFMTANWYQIPYDILDKITTRILSEVKGVNRILYDVSSKPPATIEFE 4x2q A 2.94 BS01 NAD A 1 I165 I166 W168 K192 A194 E195 Y224 G225 G229 A230 F243 S246 V249 I253 I158 I159 W161 K185 A187 E188 Y217 G218 G222 A223 F236 S239 V242 I246 1.2.1.36 O94788 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYGEFGLREYSEVKTVTVKIPQKNS 4x2q C 2.94 BS01 NAD C 1 I165 I166 W168 K192 A194 E195 G225 P226 G229 A230 F243 G245 S246 V249 I253 I158 I159 W161 K185 A187 E188 G218 P219 G222 A223 F236 G238 S239 V242 I246 1.2.1.36 O94788 LPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNAGEFGLREYSEVKTVTVKIPQKNS 4x30 A 1.55 BS01 T44 A 1 S23 S24 A27 L246 L248 L269 K270 N273 L376 E377 R378 R381 S7 S8 A11 L230 L232 L253 K254 N257 L354 E355 R356 R359 P05543 ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 4x4j A 2.65 BS01 FAD A 1 G9 G11 P12 A13 L31 E32 R33 R42 G43 Q96 H118 E119 L120 C151 D152 G153 A157 L177 G274 D275 P282 G285 Q286 G287 M288 N289 G8 G10 P11 A12 L30 E31 R32 R41 G42 Q95 H117 E118 L119 C150 D151 G152 A156 L176 G270 D271 P278 G281 Q282 G283 M284 N285 D7RFJ3 DAPVVIAGAGPAGLMLAGELRLAGIGVVVLERLPARTGESRGLGFTARTMEVFDQRGLLRRFGEVQTSDQGHFGGIPVDFGLLDGAHQAAKTIPQSATEAVLEAWAGELGADIRRGHELTGVRDDGDGVAVTVRGPAGEHVLRAGWLVGCDGGRSAVRKAVGFDFPGTAATREMFLADLRGVELEPRMSLPGGMVMVGPLPGGVTRIIVCERDAPPRRRTGPPPFHEVADAWKRITGIDISAAEPVWLSAFGDATRQVTEYRRGRVLLAGDAAHVHLPAGGQGMNAGIQDAVNLGWKLAAVVRGTARADLLDTYHGERHPVGVRLLMNTRAQGLLFLNGAEMQPLRDVLAELTGYPDVARHLAAMVSGLEIAYDVGGGSHPWLGRRLPRLELDRGGRPSSTAELLRPARGLLLDFAGNAALRDRAAPWAGRIDVVTARPAGRVPGATTAVLVRPDGHVAWAAPGTHADLPMALERWFGPAPR 4xbr A 2.94 BS01 ATP A 1 G330 S331 T332 V335 K350 M395 E396 F397 L398 D440 L447 D458 G460 F461 G57 S58 T59 V62 K77 M122 E123 F124 L125 D167 L174 D185 G187 F188 2.7.11.1 O96013 LNRGRSRQPLVLGDNCFADLVHNQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNR 4xbu A 2.06 BS01 III B 1 Q358 R359 E361 T404 K442 S443 D444 F461 L475 V476 G477 T478 P479 Y480 W481 R489 E507 E512 F516 N517 E518 M524 Q62 R63 E65 T108 K146 S147 D148 F165 L179 V180 G181 T182 P183 Y184 W185 R193 E211 E216 F220 N221 E222 M228 2.7.11.1 O96013 QRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNR 4yi8 A 1.20 BS01 CA A 1 D74 N76 D78 T80 E85 D68 N70 D72 T74 E79 P21457 26584024 GALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAIFKMISPEDTKHLPEDENTPEKRAAKIWGFFGKKDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKL 4ym5 A 4.01 BS01 NUC I 1 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 Y4 R5 P6 T8 R26 R35 R46 F47 Q48 S49 R79 V80 T81 P68431 26573481 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 4ym5 B 4.01 BS02 NUC J 1 R45 I46 G48 K79 T80 R22 I23 G25 K56 T57 P62805 26573481 DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 4ym5 E 4.01 BS01 NUC I 1 H39 Y41 R42 G44 T45 V46 A47 R49 K56 R63 K64 L65 P66 R69 R83 H2 Y4 R5 G7 T8 V9 A10 R12 K19 R26 K27 L28 P29 R32 R46 P68431 26573481 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4ym5 E 4.01 BS02 NUC J 1 H39 R40 Y41 R42 P43 T45 R72 R83 F84 Q85 S86 R116 V117 T118 H2 R3 Y4 R5 P6 T8 R35 R46 F47 Q48 S49 R79 V80 T81 P68431 26573481 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4ym5 H 4.01 BS01 NUC I 1 R29 K30 R31 S32 R33 K34 S36 I39 Y40 R1 K2 R3 S4 R5 K6 S8 I11 Y12 P06899 26573481 RKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK 4ym6 A 3.51 BS01 NUC I 1 H39 Y41 R42 P43 T45 R72 R83 F84 Q85 S86 R116 V117 T118 M120 H2 Y4 R5 P6 T8 R35 R46 F47 Q48 S49 R79 V80 T81 M83 P68431 26573481 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4ym6 A 3.51 BS02 NUC J 1 R40 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 P66 R69 R83 R3 Y4 P6 G7 T8 V9 A10 R12 R26 K27 L28 P29 R32 R46 P68431 26573481 PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 4ym6 C 3.51 BS01 NUC I 1 R11 A12 A14 R17 R20 G28 R32 R42 K74 R77 R1 A2 A4 R7 R10 G18 R22 R32 K64 R67 P04908 26573481 RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPK 4ym6 E 3.51 BS01 NUC I 1 H39 R40 Y41 P43 G44 V46 R49 K56 R63 K64 L65 P66 R69 H3 R4 Y5 P7 G8 V10 R13 K20 R27 K28 L29 P30 R33 P68431 26573481 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 4ym6 E 3.51 BS02 NUC J 1 K37 H39 Y41 R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 M120 K1 H3 Y5 R6 T9 R27 R36 R47 F48 Q49 S50 R80 V81 T82 M84 P68431 26573481 KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 4ym6 F 3.51 BS01 NUC I 1 R45 I46 K79 T80 R27 I28 K61 T62 P62805 26573481 RKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 4ym6 H 3.51 BS02 NUC J 1 R33 Y42 G53 S55 S56 R86 S87 T88 R1 Y10 G21 S23 S24 R54 S55 T56 P06899 26573481 RKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA 4ynl B 2.10 BS01 III D 1 W241 R250 A251 L252 E253 E254 D256 W20 R29 A30 L31 E32 E33 D35 P27709 26576507 ERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVGGIPMILQMVFGRK 4ynl B 2.10 BS02 III C 1 D270 I273 R274 A277 D278 H281 D49 I52 R53 A56 D57 H60 P27709 26576507 ERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVGGIPMILQMVFGRK 4ynl N 2.10 BS01 III P 1 W241 M249 R250 A251 L252 E253 E254 L255 D256 W20 M28 R29 A30 L31 E32 E33 L34 D35 P27709 26576507 ERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVGGIPMILQMVFGRK 4ynl N 2.10 BS02 III R 1 D270 I273 R274 A277 H281 D49 I52 R53 A56 H60 P27709 26576507 ERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVGGIPMILQMVFGRK 4yrv B 2.80 BS02 NUC D 1 H35 G36 Q59 N60 L61 R62 K73 K76 S179 E180 A181 H32 G33 Q56 N57 L58 R59 K70 K73 S176 E177 A178 P27709 26576507 DIDLIKRLGPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYLEQGQNLRMTGHLHHLEPKRVKIIVEEVRQALMEGKLLKTLGSQEPRYLIQFPYVWMEQYPWIPGRSRIPGTSLTSEEKRQIEHKLPSNLPDAQLVTSFEFLELIEFLHKRSQEDLPPEHRMELSEALAEHIKRRLLYSGTVTRIDSPWGMPFYALTRPFYERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVPMILQMVFGRKE 4z83 E 1.80 BS01 III I 1 Q84 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 Y204 L205 E230 G234 Y235 P236 F239 A240 D241 I246 Y247 D328 Y330 Q71 E114 F116 S117 R120 K155 P156 E157 F174 L185 C186 G187 T188 P189 E190 Y191 L192 E217 G221 Y222 P223 F226 A227 D228 I233 Y234 D315 Y317 2.7.11.11 P00517 26578105 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4z83 E 1.80 BS02 4L7 E 1 L49 G50 T51 G52 G55 R56 V57 A70 K72 L74 V104 M120 E121 Y122 A123 E127 E170 N171 M173 T183 D184 F327 L36 G37 T38 G39 G42 R43 V44 A57 K59 L61 V91 M107 E108 Y109 A110 E114 E157 N158 M160 T170 D171 F314 2.7.11.11 P00517 26578105 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4z83 E 1.80 BS03 4L7 E 2 V15 F18 F100 L152 E155 Y306 V2 F5 F87 L139 E142 Y293 2.7.11.11 P00517 26578105 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4zgs A 2.46 BS01 NAD A 1 Y134 G187 A188 I189 Y207 D208 C239 P240 L242 S244 T245 V266 S267 R268 D292 H335 A337 F338 Y110 G163 A164 I165 Y183 D184 C215 P216 L218 S220 T221 V242 S243 R244 D268 H311 A313 F314 B0LUZ5 26574578 TPQEAAKVATTRCICYSTTQYVKDFLAGPMQKVFTDTYFVEPPLDKDTAQLARGYDVAVLFVNDRADASVIKELAKAGVKLIALRCAGFDRVDLHACAEHGVRVVRVPTYSPESVAEHAVALIFALNRHLTDAYIRVRMGNYSLSGLVGVEMRHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDELLAMSDIVTLHCPLLPSTRQLINKESIQKMKKGVMLINVSRGGLIDSAALFDALESGQIGALGLDVYENEGGLFFVDHTKFDPSVRMQKWDRQFRTLLSYPQVLVTPHTAFLTEEALNNICTTTIQNIADYVLDRPLGNEVKA 4zgs B 2.46 BS01 NAD B 1 Y134 G187 A188 I189 Y207 D208 I209 C239 P240 L241 L242 S244 T245 V266 S267 R268 D292 H335 A337 F338 Y106 G159 A160 I161 Y179 D180 I181 C211 P212 L213 L214 S216 T217 V238 S239 R240 D264 H307 A309 F310 B0LUZ5 26574578 AAKVATTRCICYSTTQYVKDFLAGPMQKVFTDTYFVEPPLDKDTAQLARGYDVAVLFVNDRADASVIKELAKAGVKLIALRCAGFDRVDLHACAEHGVRVVRVPTYSPESVAEHAVALIFALNRHLTDAYIRVRMGNYSLSGLVGVEMRHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDELLAMSDIVTLHCPLLPSTRQLINKESIQKMKKGVMLINVSRGGLIDSAALFDALESGQIGALGLDVYENEGGLFFVDHTKFDPSVRMQKWDRQFRTLLSYPQVLVTPHTAFLTEEALNNICTTTIQNIADYVLDRPLGN 4zgs F 2.46 BS01 NAD F 1 Y134 G187 A188 I189 D208 I209 K210 C239 P240 S244 T245 V266 S267 R268 D292 H335 A337 F338 Y109 G162 A163 I164 D183 I184 K185 C214 P215 S219 T220 V241 S242 R243 D267 H310 A312 F313 B0LUZ5 26574578 PQEAAKVATTRCICYSTTQYVKDFLAGPMQKVFTDTYFVEPPLDKDTAQLARGYDVAVLFVNDRADASVIKELAKAGVKLIALRCAGFDRVDLHACAEHGVRVVRVPTYSPESVAEHAVALIFALNRHLTDAYIRVRMGNYSLSGLVGVEMRHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDELLAMSDIVTLHCPLLPSTRQLINKESIQKMKKGVMLINVSRGGLIDSAALFDALESGQIGALGLDVYENEGGLFFVDHTKFDPSVRMQKWDRQFRTLLSYPQVLVTPHTAFLTEEALNNICTTTIQNIADYVLDRPLGNEV 5a6t C 1.65 BS03 SO3 C 1 H137 H139 A170 K220 H222 H249 H275 D363 A366 H137 H139 A170 K220 H222 H249 H275 D363 A366 3.5.1.5 P41020 26580226 MKINRQQYAESYGPTVGDQVRLADTDLWIEVEKDYTTYGDEANFGGGKVLREGMGENGTYTRTENVLDLLLTNALILDYTGIYKADIGVKDGYIVGIGKGGNPDIMDGVTPNMIVGTATEVIAAEGKIVTAGGIDTHVHFINPDQVDVALANGITTLFGGGTGPAEGSKATTVTPGPWNIEKMLKSTEGLPINVGILGKGHGSSIAPIMEQIDAGAAGLKIHEDWGATPASIDRSLTVADEADVQVAIHSDTLNEAGFLEDTLRAINGRVIHSFHVEGAGGGHAPDIMAMAGHPNVLPSSTNPTRPFTVNTIDEHLDMLMVCHHLKQNIPEDVAFADSRIRPETIAAEDILHDLGIISMMSTDALAMGRAGEMVLRTWQTADKMKKQRGPLAEEKNGSDNFRAKRYVSKYTINPAIAQGIAHEVGSIEEGKFADLVLWEPKFFGVKADRVIKGGIIAYAQIGDPSASIPTPQPVMGRRMYGTVGDLIHDTNITFMSKSSIQQGVPAKLGLKRRIGTVKNCRNIGKKDMKWNDVTTDIDINPETYEVKVDGEVLTCEPVKELPMAQRYFLF 5a8l G 3.80 BS01 NUC A 1 Y14 R57 A77 S78 N97 A122 K130 E131 Y8 R51 A71 S72 N91 A116 K124 E125 P30050 26384426 PNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVD 5a8l Q 3.80 BS01 NUC A 1 D43 R47 M51 E55 N121 T122 S123 G153 N164 L176 K178 K179 H180 G181 R182 G184 Q185 S186 L188 R189 F190 R192 L193 E196 H199 R203 S229 A230 F232 R245 D255 S257 N265 S295 D297 G315 A316 K383 K384 F385 G386 R414 Y415 F432 D435 D436 D37 R41 M45 E49 N115 T116 S117 G147 N158 L170 K172 K173 H174 G175 R176 G178 Q179 S180 L182 R183 F184 R186 L187 E190 H193 R197 S223 A224 F226 R239 D249 S251 N259 S289 D291 G309 A310 K377 K378 F379 G380 R408 Y409 F426 D429 D430 P62495 26384426 AADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY 5a8l Q 3.80 BS02 NUC B 1 N61 K63 R65 V66 R68 L69 T76 S77 Q80 R81 L126 D128 N55 K57 R59 V60 R62 L63 T70 S71 Q74 R75 L120 D122 P62495 26384426 AADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY 5a8l Q 3.80 BS03 NUC P 1 S46 K50 D54 G183 Q185 S40 K44 D48 G177 Q179 P62495 26384426 AADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY 5a8l Q 3.80 BS04 NUC R 1 T32 E55 T58 N61 I62 K63 V71 C127 T26 E49 T52 N55 I56 K57 V65 C121 P62495 26384426 AADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY 5acl A 1.49 BS01 SAS A 1 Y34 V35 S36 Y38 Y51 E52 P57 F99 Y33 V34 S35 Y37 Y50 E51 P56 F98 P01709 26576950 SALTQPPSASGSLGQSVTISCTGTSSDVGGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYEGSDNFVFGTGTKVTVL 5acm A 1.05 BS01 MBT A 1 Y34 Y93 D97 F99 Y33 Y92 D96 F98 P01709 26576950 SALTQPPSASGSLGQSVTISCTGTSSDVGGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCSSYEGSDNFVFGTGTKVTVL 5ajr A 2.75 BS01 HEM A 1 Y103 A288 A291 G292 T295 T299 V359 R361 G414 F415 G416 H420 K421 C422 I423 G424 Y75 A259 A262 G263 T266 T270 V330 R332 G385 F386 G387 H391 K392 C393 I394 G395 1.14.13.70 Q7Z1V1 KKTPPVYPVTVPFLGHIVQFGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSRFFSPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHEVRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFGEDLRKRLNARHFAQLLSKMESSLIPAAVFMPWLLRLLPQSARCREARAELQKILGEIIVAREKEEASKDNNTSDLLGGLLKAVYRDGTRMSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNVMDEMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNPRLWDPERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEVPDPDYHTMVVGPTLNQCLVKYTRKKK 5ajr A 2.75 BS02 VT1 A 1 Y103 M106 Y116 A287 A291 T295 L356 M358 M360 M460 Y75 M78 Y88 A258 A262 T266 L327 M329 M331 M431 1.14.13.70 Q7Z1V1 KKTPPVYPVTVPFLGHIVQFGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSRFFSPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHEVRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFGEDLRKRLNARHFAQLLSKMESSLIPAAVFMPWLLRLLPQSARCREARAELQKILGEIIVAREKEEASKDNNTSDLLGGLLKAVYRDGTRMSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNVMDEMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNPRLWDPERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEVPDPDYHTMVVGPTLNQCLVKYTRKKK 5b0p A 1.90 BS01 GOL A 1 R46 L103 E140 K188 R46 L103 E140 K188 Q92DF6 MNIYRYEENPLITPLDVKPIHEGFEVIGAFNGGVAEYNGEVLLLLRVAEKPVSEDPEIVLAPVYNAKNKELELQSFRLDDENYDFEDPRMIRSKAKLEGFSYLTSLSYIRIARSKDGHHFTLDEKPFLYPFNEYQTFGIEDARVTQIGDTYHVNFSAVSEFGVADALVTTKDFENLEYQGNIFAPENKDVLIFPEKINGKYYALHRPSLKSIGNLDIWIASSPDLRSFGDHRHLLGIRPGEYDSGRVGGGCVPIKTEEGWLILYHGATEENRYVMGAALLDLNDPTIVLKRTKTPILEPVADYEKNGFFGDVVFACGAIQEGDTLHMYYGVADTSMAGCDMKISEILHQLEVEA 5b0p A 1.90 BS02 GOL A 2 N31 R89 Y273 F314 D333 N31 R89 Y273 F314 D333 Q92DF6 MNIYRYEENPLITPLDVKPIHEGFEVIGAFNGGVAEYNGEVLLLLRVAEKPVSEDPEIVLAPVYNAKNKELELQSFRLDDENYDFEDPRMIRSKAKLEGFSYLTSLSYIRIARSKDGHHFTLDEKPFLYPFNEYQTFGIEDARVTQIGDTYHVNFSAVSEFGVADALVTTKDFENLEYQGNIFAPENKDVLIFPEKINGKYYALHRPSLKSIGNLDIWIASSPDLRSFGDHRHLLGIRPGEYDSGRVGGGCVPIKTEEGWLILYHGATEENRYVMGAALLDLNDPTIVLKRTKTPILEPVADYEKNGFFGDVVFACGAIQEGDTLHMYYGVADTSMAGCDMKISEILHQLEVEA 5b0p A 1.90 BS03 GOL A 3 L234 L235 G236 R291 L234 L235 G236 R291 Q92DF6 MNIYRYEENPLITPLDVKPIHEGFEVIGAFNGGVAEYNGEVLLLLRVAEKPVSEDPEIVLAPVYNAKNKELELQSFRLDDENYDFEDPRMIRSKAKLEGFSYLTSLSYIRIARSKDGHHFTLDEKPFLYPFNEYQTFGIEDARVTQIGDTYHVNFSAVSEFGVADALVTTKDFENLEYQGNIFAPENKDVLIFPEKINGKYYALHRPSLKSIGNLDIWIASSPDLRSFGDHRHLLGIRPGEYDSGRVGGGCVPIKTEEGWLILYHGATEENRYVMGAALLDLNDPTIVLKRTKTPILEPVADYEKNGFFGDVVFACGAIQEGDTLHMYYGVADTSMAGCDMKISEILHQLEVEA 5b0q A 2.30 BS01 MAN A 1 R46 M90 L103 E140 K188 R46 M90 L103 E140 K188 Q92DF6 MNIYRYEENPLITPLDVKPIHEGFEVIGAFNGGVAEYNGEVLLLLRVAEKPVSEDPEIVLAPVYNAKNKELELQSFRLDDENYDFEDPRMIRSKAKLEGFSYLTSLSYIRIARSKDGHHFTLDEKPFLYPFNEYQTFGIEDARVTQIGDTYHVNFSAVSEFGVADALVTTKDFENLEYQGNIFAPENKDVLIFPEKINGKYYALHRPSLKSIGNLDIWIASSPDLRSFGDHRHLLGIRPGEYDSGRVGGGCVPIKTEEGWLILYHGATEENRYVMGAALLDLNDPTIVLKRTKTPILEPVADYEKNGFFGDVVFACGAIQEGDTLHMYYGVADTSMAGCDMKISEILHQLEVE 5b0q B 2.30 BS01 MAN B 1 R46 R89 M90 L103 E140 K188 R46 R89 M90 L103 E140 K188 Q92DF6 MNIYRYEENPLITPLDVKPIHEGFEVIGAFNGGVAEYNGEVLLLLRVAEKPVSEDPEIVLAPVYNAKNKELELQSFRLDDENYDFEDPRMIRSKAKLEGFSYLTSLSYIRIARSKDGHHFTLDEKPFLYPFNEYQTFGIEDARVTQIGDTYHVNFSAVSEFGVADALVTTKDFENLEYQGNIFAPENKDVLIFPEKINGKYYALHRPSLKSIGNLDIWIASSPDLRSFGDHRHLLGIRPGEYDSGRVGGGCVPIKTEEGWLILYHGATEENRYVMGAALLDLNDPTIVLKRTKTPILEPVADYEKNGFFGDVVFACGAIQEGDTLHMYYGVADTSMAGCDMKISEILHQLEVEA 5c2e A 2.10 BS02 4PX A 1 Y514 H515 L625 D664 L665 S667 V668 I682 F686 M703 Q716 F719 Y78 H79 L189 D228 L229 S231 V232 I246 F250 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 26378882 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 5c5x A 2.60 BS01 PS6 D 1 G159 S160 L163 G158 S159 L162 P55064 26569106 KKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTEPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYEP 5c5x D 2.60 BS01 PS6 D 1 P157 V158 G159 S160 L163 P156 V157 G158 S159 L162 P55064 26569106 KKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTEPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYEP 5c5x E 2.60 BS01 PS6 H 1 G159 L163 G158 L162 P55064 26569106 KKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTEPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYEP 5cgh L 2.50 BS01 III e 1 R101 D126 S130 R101 D126 S130 3.4.25.1 P23724 26563572 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5cgh L 2.50 BS02 MG L 1 I35 D222 I35 D222 3.4.25.1 P23724 26563572 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 5cul B 2.90 BS01 III A 1 T49 V51 A52 I53 G54 I55 R56 Y57 T68 L69 H71 R78 V79 I82 A83 E85 E86 I88 P89 V90 L91 Q92 R93 I94 A97 D107 L122 T2 V4 A5 I6 G7 I8 R9 Y10 T21 L22 H24 R31 V32 I35 A36 E38 E39 I41 P42 V43 L44 Q45 R46 I47 A50 D60 L75 Q9I337 26589798 PTHVAIGIRYRRGETPLPLVTLKHTDALALRVRRIAEEEGIPVLQRIPLARALLRDGNVDQYIPADLIQATAEVLRWLE 5d3q A 1.70 BS01 GDP A 1 S41 A42 G43 K44 S45 S46 K206 D208 L209 V235 N236 R237 S238 Q239 I242 S37 A38 G39 K40 S41 S42 K202 D204 L205 V231 N232 R233 S234 Q235 I238 3.6.5.5,3.6.5.5 Q05193 GMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVERVDEMLRMYHALKEALSIIG 5d7p A 1.76 BS03 OCZ A 1 I93 F131 A135 L138 Y139 P140 G141 I169 D170 F190 I40 F78 A82 L85 Y86 P87 G88 I116 D117 F137 3.5.1.- Q8IXJ6 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 5d7p A 1.76 BS04 OCZ A 2 P94 F96 F119 Q167 N168 I169 D170 I232 F234 P41 F43 F66 Q114 N115 I116 D117 I179 F181 3.5.1.- Q8IXJ6 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 5d7p B 1.76 BS03 OCZ B 1 F131 A135 L138 Y139 G141 D170 F190 F76 A80 L83 Y84 G86 D115 F135 3.5.1.- Q8IXJ6 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7p B 1.76 BS04 OCZ B 2 I93 F96 F119 Q167 N168 I169 D170 H187 I232 F234 I38 F41 F64 Q112 N113 I114 D115 H132 I177 F179 3.5.1.- Q8IXJ6 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q A 2.01 BS03 4I5 A 1 I93 P94 F96 F119 Q167 N168 I169 D170 H187 I232 V233 F234 I40 P41 F43 F66 Q114 N115 I116 D117 H134 I179 V180 F181 3.5.1.- Q8IXJ6 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q A 2.01 BS04 4I5 A 2 I93 F119 F131 A135 L138 Y139 G141 D170 I40 F66 F78 A82 L85 Y86 G88 D117 3.5.1.- Q8IXJ6 HMERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 5d7q B 2.01 BS04 4I5 B 2 I93 F119 F131 A135 L138 Y139 G141 D170 F190 I38 F64 F76 A80 L83 Y84 G86 D115 F135 3.5.1.- Q8IXJ6 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 5d88 A 1.66 BS01 ZN A 1 C68 H189 C81 H202 Q8TWX5 GSWSHPQFEKSGSMTRRWYLCCSRHHLDTVPEDSDGIVVPVTEHGVATLLPRYPETYEVEDIVDVAKDRGLSVQALMDFTCAGCEHLSPDGYPSLRSTLDYLASDLEVDGVVVADPYLVEVLATEYDLTVVVSHTAAVDTPEKAWHFERLGADVITVDPALNSNEEEVSAIRERVSVELRTAVGAITFRDPVAFFERNLFSHATAEGIEVDPYRNNPYEPMRERVVVWEVREELFDEVFILASGEPP 5dor B 2.50 BS01 ZN B 1 H269 H273 H101 H105 P36932 26453836 TGYLTQEEIALLLAALDGDNKKIAILCLSTGARWGEAARLKAENIIHNRVTFVKKPRTVPISEAVAKMIADGFLFPDADYPRFRRTMKAIKPDLPMGQATHALRHSFATHFMINGGSIITLQRILGHTRIEQTMVYAHFAPEYLQDAISLNPLRGGTEAES 5dye A 3.50 BS01 PS6 B 1 T155 P157 G159 S160 T154 P156 G158 S159 P55064 26569106 KKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTEPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYE 5e2z C 2.62 BS01 SIA C 1 Y98 V135 S136 S137 W153 H183 E190 R193 L194 Y94 V133 S134 S135 W151 H181 E188 R191 L192 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e2z A 2.62 BS01 SIA A 1 Y98 G134 V135 S136 S137 W153 H183 E190 R193 L194 Y94 G132 V133 S134 S135 W151 H181 E188 R191 L192 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e2z E 2.62 BS01 SIA E 1 Y98 V135 S136 S137 W153 H183 E190 R193 Y94 V133 S134 S135 W151 H181 E188 R191 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e30 C 2.70 BS01 SIA C 1 Y98 G134 V135 S136 S137 W153 H183 E190 L194 L226 Y94 G132 V133 S134 S135 W151 H181 E188 L192 L224 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e30 C 2.70 BS02 GAL C 1 K222 G225 L226 K220 G223 L224 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e30 A 2.70 BS02 GAL A 1 K222 L226 K220 L224 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e30 E 2.70 BS01 SIA E 1 Y98 G134 V135 S136 S137 W153 T155 H183 E190 L226 Y94 G132 V133 S134 S135 W151 T153 H181 E188 L224 G8IPF0 26586437 DPGDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCNLDGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKINPANDLCYPGNFNDYEELKHLLSRINHFEKIQITPKNSWSDHEASGVSSACPYQGRSSFFRNVVWLTKKDNAYPTIKRSYNNTNQEDLLVLWGIHHPNDATEQTRLYQNPTTYISVGTSTLNQKLVPKIATRSKVKGLSGRMEFFWTILKSNDAINFESNGNFIAPENAYKIVKKGDSTIMKSELEYGDCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNSP 5e34 A 2.70 BS01 SIA A 1 Y98 G134 V135 S136 S137 W153 H183 N186 E190 I194 L226 Y94 G132 V133 S134 S135 W151 H181 N184 E188 I192 L224 C4P282 26586437 DPGDQICVGYHANNSTEQVDTIMEKNITVTHAQDILEKTHNGKLCNLNGVKPLILKDCSVAGWLLGNPMCDEFLNVSEWSYIVEKASPANGLCYPGDFNDYEELKHLLSRINHFEKIKIIPKSYWSNHETSGVSSACSYLENPSFFRNVVWLTKKDNTYPPIKVNYTNANQKDLLVLWGIHHPNNEAEQKMIYQNLNTYVSVGTSTLNQRLVPKIATRSKVKGLSGRMDFFWTILKPNDTINFDSNGNFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPIGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNAP 5e4w C 2.80 BS01 III E 1 D273 D312 G316 L317 E318 Y319 A320 W343 D345 W351 E352 N356 D358 S359 D9 D48 G52 L53 E54 Y55 A56 W79 D81 W87 E88 N92 D94 S95 O22265 26568381 QVFEYAEVDEIVEKRGKGKDVEYLVRWKDGGDCEWVKGVHVAEDVAKDYEDGLEYAVAESVIGKRVGDDGKTIEYLVKWTDMSDATWEPQDNVDSTLVLLYQQQQ 5e4w D 2.80 BS01 III F 1 D273 E274 D312 Y313 G316 L317 E318 Y319 A320 W343 D345 M346 E352 N356 D9 E10 D48 Y49 G52 L53 E54 Y55 A56 W79 D81 M82 E88 N92 O22265 26568381 QVFEYAEVDEIVEKRGKGKDVEYLVRWKDGGDCEWVKGVHVAEDVAKDYEDGLEYAVAESVIGKRVGDDGKTIEYLVKWTDMSDATWEPQDNVDSTLVLLYQQQQ 5e4x A 2.75 BS01 MG A 1 D345 S347 D27 S29 O22265 26568381 YAVAESVIGKRVGDDGKTIEYLVKWTDMSDATWEPQDNVDSTLVLLYQQQ 5e7j A 2.23 BS01 AMP A 1 Y200 R202 T204 Q207 T226 G227 S228 G229 K230 T231 Y57 R59 T61 Q64 T83 G84 S85 G86 K87 T88 3.6.4.13 O00571 EDDWSKPLPPSERLEQELFSGGIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 5e7m A 2.30 BS01 ANP A 1 Y200 R202 P203 T204 Q207 T226 G227 S228 G229 K230 T231 L278 Q281 E348 Y55 R57 P58 T59 Q62 T81 G82 S83 G84 K85 T86 L127 Q130 E197 3.6.4.13 O00571 DDWSKPLPPSERLEQELFSGIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMA 5edq A 2.80 BS01 5N3 A 1 L718 G719 F723 V726 A743 K745 E762 M766 L777 L788 M790 Q791 L792 M793 L844 L22 G23 F27 V30 A47 K49 E66 M70 L81 L92 M94 Q95 L96 M97 L148 2.7.10.1 P00533 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFDMDDVVDADEYLI 5edr A 2.60 BS01 5N4 A 1 L718 V726 A743 K745 E762 M766 L788 M790 Q791 L792 M793 L844 L22 V30 A47 K49 E64 M68 L90 M92 Q93 L94 M95 L146 2.7.10.1 P00533 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYEEDMDDVVDADEYLI 5ej2 A 2.15 BS01 NAD A 1 G22 R25 G26 Q27 D46 I47 I51 S59 V83 D84 V85 N111 A112 G113 V114 I135 T163 S164 S165 Y178 K182 P208 T209 Q210 V211 T213 M215 V216 G13 R16 G17 Q18 D37 I38 I42 S50 V74 D75 V76 N102 A103 G104 V105 I126 T154 S155 S156 Y169 K173 P199 T200 Q201 V202 T204 M206 V207 1.1.1.275 A0A0H2ZYS9 25613812 TGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWVDASDISNAVLFLASDESRYVTGVSLPVDAGSLLK 5eks A 1.85 BS01 NAD A 1 N41 T43 V44 Y48 D70 E72 K75 G103 G104 V105 D108 T128 T129 L131 D135 S136 K141 N151 Q168 T171 L172 E176 N42 T44 V45 Y49 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 Q169 T172 L173 E177 4.2.3.4 V5V8R5 HMQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGKTVATCILPDGEKYKDIQHLNLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQVVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKERALLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQIPLDDFLGYMAHDKKVQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG 5eks A 1.85 BS02 MG A 1 E183 H246 H263 E184 H244 H261 4.2.3.4 V5V8R5 HMQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGKTVATCILPDGEKYKDIQHLNLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQVVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKERALLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQIPLDDFLGYMAHDKKVQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG 5el0 A 1.85 BS01 NAP A 1 G33 A34 S35 S57 R58 V77 D78 L79 A110 G111 I112 A216 L218 G9 A10 S11 S33 R34 V53 D54 L55 A86 G87 I88 A192 L194 A0A0H3AQ75 ERKTLVLTGASRGIGHATVKRFSLAGWRVITCSRQDFSENCPWPAGPEDHIKVDLSDPEDIGKAIAEIRRRLEANGSKLHALVNNAGISPKAEGGRRMNSIETPMAVWRDVFQVNFMAPIMLARGLFKELEAAQGSVVNVTSIAGSRVHPFAGTAYATSKAALAALTREMASDFGPYGIRVNAIAPGEIDTAILGKTSEVAETIYFLCTETSSYVTGSEIHIN 5es1 A 2.80 BS01 5RC A 1 K64 G65 V70 A83 I84 K85 M132 E133 Y134 A135 G138 E182 N183 D196 K14 G15 V20 A33 I34 K35 M82 E83 Y84 A85 G88 E132 N133 D146 2.7.11.1 Q96L34 PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRK 5euf A 2.80 BS01 ZN A 1 H78 H82 E158 H47 H51 E127 3.4.-.- I9VHL9 LPKHESVTLKNGLQVVSVPLKTGVIEVDVLYKVGSRNEVMGKSGIAHMLEHLNFKSTKNLKAGEFDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFLPERQVVAEERRWRTDNSPIGMLYFRFFNTAYVYHPYHWTPIGFMDDIQNWTLKDIKKFHSLYYQPKNAIVLVVGDVNSQKVFELTKKHFESLKNLDEKAIPTPYMKEPKQDGARTAVVHKDGVHLEWVALGYKVPAFKHKDQVALDALSKLLGEGKSSWLQSELVDKKRLASQAFSHNMQLQDESVFLFIAGGNPNIKAEALQKEIVALLEKLKKGEITQAELDKIKINQKADFISNLESSSDVAGLFADYLVQNDLQGLTDYQQQFLDLKVSDLVRVANEYFKDTQSTTVFLKP 5evc A 1.70 BS01 K A 1 M11 G12 P82 C83 N84 K163 C193 T194 E195 M15 G16 P86 C87 N88 K167 C197 T198 E199 Q8ZJZ9 QSNAMKHTIGILGGMGPAATADMLEKFVELRHASCDQQHIPLIVSSIPDIPDRTACLLSGGPSPYRYLERYLHMLEDAGAECIVIPCNTAHYWFDDLQNVAKARMISILDATLGDIPPSARHVGLLATNATLATGLYQKKALARGLTLIQPEDAGQALVMQAIYTLKRGDKTAAQALLLPQIDSLIARGAQAIIMGCTEIPLIVAGHERAIACPMIDSTASLVRAAIRWYESWPDTR 5evc A 1.70 BS02 SO4 A 1 M11 R49 C83 T85 T124 K163 M15 R53 C87 T89 T128 K167 Q8ZJZ9 QSNAMKHTIGILGGMGPAATADMLEKFVELRHASCDQQHIPLIVSSIPDIPDRTACLLSGGPSPYRYLERYLHMLEDAGAECIVIPCNTAHYWFDDLQNVAKARMISILDATLGDIPPSARHVGLLATNATLATGLYQKKALARGLTLIQPEDAGQALVMQAIYTLKRGDKTAAQALLLPQIDSLIARGAQAIIMGCTEIPLIVAGHERAIACPMIDSTASLVRAAIRWYESWPDTR 5evc A 1.70 BS03 K A 2 V24 E25 L26 R27 H28 A29 H35 V28 E29 L30 R31 H32 A33 H39 Q8ZJZ9 QSNAMKHTIGILGGMGPAATADMLEKFVELRHASCDQQHIPLIVSSIPDIPDRTACLLSGGPSPYRYLERYLHMLEDAGAECIVIPCNTAHYWFDDLQNVAKARMISILDATLGDIPPSARHVGLLATNATLATGLYQKKALARGLTLIQPEDAGQALVMQAIYTLKRGDKTAAQALLLPQIDSLIARGAQAIIMGCTEIPLIVAGHERAIACPMIDSTASLVRAAIRWYESWPDTR 5ex4 A 2.25 BS05 TRP B 1 D10 V170 Y173 D10 V170 Y173 2.5.1.54 A0A0E8NFD1 MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5ex4 B 2.25 BS01 TRP A 3 I7 V55 Y173 I9 V55 Y173 2.5.1.54 A0A0E8NFD1 GAMNWTVDIPIDQSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5ex4 B 2.25 BS04 TRP B 2 V111 K123 A192 N237 L238 T240 V111 K123 A192 N237 L238 T240 2.5.1.54 A0A0E8NFD1 GAMNWTVDIPIDQSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD 5ex4 B 2.25 BS06 TRP B 3 L15 P16 L18 R23 L26 E53 R256 L259 R260 L271 L15 P16 L18 R23 L26 E53 R256 L259 R260 L271 2.5.1.54 A0A0E8NFD1 GAMNWTVDIPIDQSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD