2n5h A BS01 PNS A 1 L35 L40 N41 S42 I45 V46 I65 T66 G67 L35 L40 N41 S42 I45 V46 I65 T66 G67 Q4KCZ1 26340431 MDGEEVKEKIRRYIMEDLIGPSAKEDELDDQTPLLEWGILNSMNIVKLMVYIRDEMGVSIPSTHITGKYFKDLNAISRTVEQLKAESALE 2n5i A BS01 4EM A 1 S42 I45 I65 T66 G67 S42 I45 I65 T66 G67 Q4KCZ1 26340431 MDGEEVKEKIRRYIMEDLIGPSAKEDELDDQTPLLEWGILNSMNIVKLMVYIRDEMGVSIPSTHITGKYFKDLNAISRTVEQLKAESALE 3wy6 A 1.45 BS03 BGC A 1 N82 K133 W135 W180 N33 K84 W86 W131 3.2.1.4 Q9V2T0 KVLKIRYPDDGEWPGAPIDKDGDGNPEFYIEINLWNILNATGFAEMTYNLTSGVLHYVQQLDNIVLRDRSNWVHGYPEIFYGNKPWNANYATDGPIPLPSKVSNLTDFYLTISYKLEPKNGLPINFAIESWLTREAWRTTGINSDEQAVMIWIYYDGLQPAGSKVKEIVVPIIVNGTPVNATFEVWKANIGWEYVAFRIKTPIKEGTVTIPYGAFISVAANISSLPNYTELYLEDVEIGTEFGTPSTTSAHLEWWITNITLTPLDRPLIS 3wy6 A 1.45 BS04 BGC A 2 N120 M199 W201 Q208 P209 A210 Y243 E290 N71 M150 W152 Q159 P160 A161 Y194 E241 3.2.1.4 Q9V2T0 KVLKIRYPDDGEWPGAPIDKDGDGNPEFYIEINLWNILNATGFAEMTYNLTSGVLHYVQQLDNIVLRDRSNWVHGYPEIFYGNKPWNANYATDGPIPLPSKVSNLTDFYLTISYKLEPKNGLPINFAIESWLTREAWRTTGINSDEQAVMIWIYYDGLQPAGSKVKEIVVPIIVNGTPVNATFEVWKANIGWEYVAFRIKTPIKEGTVTIPYGAFISVAANISSLPNYTELYLEDVEIGTEFGTPSTTSAHLEWWITNITLTPLDRPLIS 3wy6 A 1.45 BS05 BGC A 3 W121 Q208 A210 W72 Q159 A161 3.2.1.4 Q9V2T0 KVLKIRYPDDGEWPGAPIDKDGDGNPEFYIEINLWNILNATGFAEMTYNLTSGVLHYVQQLDNIVLRDRSNWVHGYPEIFYGNKPWNANYATDGPIPLPSKVSNLTDFYLTISYKLEPKNGLPINFAIESWLTREAWRTTGINSDEQAVMIWIYYDGLQPAGSKVKEIVVPIIVNGTPVNATFEVWKANIGWEYVAFRIKTPIKEGTVTIPYGAFISVAANISSLPNYTELYLEDVEIGTEFGTPSTTSAHLEWWITNITLTPLDRPLIS 4re2 A 2.00 BS01 MVL A 1 Q32 H133 Y134 N178 E179 Y318 W361 E389 W436 E443 W444 F452 Q36 H137 Y138 N182 E183 Y322 W365 E393 W440 E447 W448 F456 3.2.1.25 B5ABY0 APFTYWLNPEIYDAGGLSRRAFPEGFVFGTAASAYQVEGMAKQGGRGPSIWDAFIEKPGTIPNNATADVTVDEYHRYKEDVNIMKNMGFDAYRFSISWSRIFPNGTGMVNQEGVDYYNRLIDYMVKKGIKPYANLYHYDLPLALHEQYLGWLSPNIVEAFADYADFCFQTFGDRVKDWFTFNEPRCVAALGYDNGFHAPGRCSGCDAGGNSTTEPYLAAHHLILSHAAAVKRYREKYQLYQKGRIGILLDFVWYEPFSDSNADRAAAQRARDFHLGWFLDPIIHGRYPYSMLEIVKDRMPTFSDEESRMVKDSIDYVGINHYTSFYMKDPGPWNLTPTSYQDDWHVGFAYERNGVPIGAQANSYWLYIVPWGINKAVTYVKETYGNPTMILSENGMDQPGNVSITQGVHDTVRIRYYRNYITELKKAIDDGAKVIGYFAWSLLDNFEWRLGYTSRFGIVYVDYKTLKRYPKDSAFWFKNMLS 4rfw A 2.40 BS01 III G 1 F277 V280 K284 L294 V298 L301 R302 F450 E453 E456 A457 F33 V36 K40 L50 V54 L57 R58 F206 E209 E212 A213 P19793 26331194 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4rfw A 2.40 BS02 3RB A 1 I268 A271 A272 Q275 F313 R316 L326 A327 I345 F346 C432 L436 F439 I24 A27 A28 Q31 F69 R72 L82 A83 I101 F102 C188 L192 F195 P19793 26331194 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4rmc A 2.70 BS02 3SV A 1 A271 A272 Q275 W305 F313 R316 I324 L326 A327 F346 V349 C432 L436 F439 A27 A28 Q31 W61 F69 R72 I80 L82 A83 F102 V105 C188 L192 F195 P19793 26331194 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4rme A 2.30 BS02 3T2 A 1 I268 A271 A272 Q275 W305 N306 F313 R316 I324 L326 A327 F346 V349 C432 H435 L436 I24 A27 A28 Q31 W61 N62 F69 R72 I80 L82 A83 F102 V105 C188 H191 L192 P19793 26331194 EDMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4rsb C 2.69 BS01 NUC P 1 G2 K3 I4 S5 T6 K29 Y41 Q42 R49 G1 K2 I3 S4 T5 K28 Y40 Q41 R48 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 4rsb C 2.69 BS02 NUC N 1 Y9 P40 Q42 T43 N47 E64 Y8 P39 Q41 T42 N46 E63 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 4rsb D 2.69 BS01 NUC P 1 G2 K3 K8 Y9 P14 R15 P40 Q42 T43 Q46 N47 G1 K2 K7 Y8 P13 R14 P39 Q41 T42 Q45 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEV 4rsb D 2.69 BS02 NUC N 1 G2 K3 I4 S5 S31 Y41 Q42 I45 R49 G1 K2 I3 S4 S30 Y40 Q41 I44 R48 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEV 4rsb A 2.69 BS01 NUC P 1 A30 S31 Y41 Q42 I45 I66 Y68 A26 S27 Y37 Q38 I41 I62 Y64 O93706 26339031 STDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4rsb A 2.69 BS02 NUC N 1 Y9 P14 P40 Q42 T43 Q46 N47 E64 Y5 P10 P36 Q38 T39 Q42 N43 E60 O93706 26339031 STDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4rsb B 2.69 BS01 NUC P 1 G2 K3 Y9 P14 P40 Q42 T43 Q46 N47 E64 G1 K2 Y8 P13 P39 Q41 T42 Q45 N46 E63 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4rsb B 2.69 BS02 NUC N 1 G2 K3 I4 S5 K29 Y41 Q42 I45 R49 I66 Y68 G1 K2 I3 S4 K28 Y40 Q41 I44 R48 I65 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4rsb E 2.69 BS01 NUC P 1 K8 Y9 P14 P40 Q42 T43 N47 K7 Y8 P13 P39 Q41 T42 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 4rsb E 2.69 BS02 NUC N 1 G2 K3 I4 S5 T6 Y41 Q42 R49 G1 K2 I3 S4 T5 Y40 Q41 R48 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 4rsb F 2.69 BS02 NUC N 1 G2 K3 Y9 P14 R15 P40 Q42 T43 Q46 N47 G1 K2 Y8 P13 R14 P39 Q41 T42 Q45 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4ru7 C 2.98 BS01 NUC P 1 G2 K3 I4 S5 T6 A30 S31 Y41 I45 R49 G1 K2 I3 S4 T5 A29 S30 Y40 I44 R48 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 4ru7 C 2.98 BS02 NUC N 1 G2 K8 Y9 P14 P40 Q42 T43 Q46 N47 G1 K7 Y8 P13 P39 Q41 T42 Q45 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVV 4ru7 D 2.98 BS02 NUC N 1 G2 K3 I4 S5 A30 S31 Y41 Q42 I45 R49 E65 I66 Y68 G1 K2 I3 S4 A29 S30 Y40 Q41 I44 R48 E64 I65 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4ru7 A 2.98 BS01 NUC P 1 T6 K29 S31 Y41 Q42 R49 I66 Y68 T1 K24 S26 Y36 Q37 R44 I61 Y63 O93706 26339031 TDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQHHHHH 4ru7 A 2.98 BS02 NUC N 1 Y9 P14 P40 Q42 T43 Q46 N47 Y4 P9 P35 Q37 T38 Q41 N42 O93706 26339031 TDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQHHHHH 4ru7 B 2.98 BS01 NUC P 1 K3 I4 Y9 P14 P40 Q42 T43 Q46 N47 E64 K2 I3 Y8 P13 P39 Q41 T42 Q45 N46 E63 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQHHHHHHH 4ru7 B 2.98 BS02 NUC N 1 G2 K3 S5 A30 S31 Y41 Q42 R49 E65 I66 Y68 G1 K2 S4 A29 S30 Y40 Q41 R48 E64 I65 Y67 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQHHHHHHH 4ru7 F 2.98 BS02 NUC N 1 G2 K3 I4 K8 Y9 R15 P40 Q42 T43 Q46 N47 G1 K2 I3 K7 Y8 R14 P39 Q41 T42 Q45 N46 O93706 26339031 GKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ 4rzr A 2.20 BS01 NUC B 1 V32 S34 G41 A42 A44 G58 G218 E219 A220 R240 R242 K243 S244 I245 G246 R247 I248 T250 R331 R332 R336 V32 S34 G41 A42 A44 G58 G218 E219 A220 R240 R242 K243 S244 I245 G246 R247 I248 T250 R331 R332 R336 2.7.7.7 Q97W02 26327169 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFIE 4rzr A 2.20 BS02 NUC C 1 S103 D105 E106 K152 P184 G185 G187 I189 T190 K193 I295 V296 S297 R298 G299 R300 T301 S103 D105 E106 K152 P184 G185 G187 I189 T190 K193 I295 V296 S297 R298 G299 R300 T301 2.7.7.7 Q97W02 26327169 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFIE 4rzr D 2.20 BS01 NUC E 1 V32 F33 S34 R36 S40 G41 A42 P60 V62 E63 M76 K78 G218 E219 A220 R242 K243 S244 I245 G246 R247 I248 T250 L293 R331 R332 R336 V32 F33 S34 R36 S40 G41 A42 P60 V62 E63 M76 K78 G218 E219 A220 R242 K243 S244 I245 G246 R247 I248 T250 L293 R331 R332 R336 2.7.7.7 Q97W02 26327169 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFIE 4rzr D 2.20 BS02 NUC F 1 K152 P184 G185 I186 G187 I189 T190 K193 D294 V296 S297 R298 G299 T301 K152 P184 G185 I186 G187 I189 T190 K193 D294 V296 S297 R298 G299 T301 2.7.7.7 Q97W02 26327169 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFIE 4wef A 2.50 BS01 FSI A 1 R192 E276 Y337 E409 R424 R502 Y530 R51 E135 Y196 E268 R283 R361 Y389 Q6WJ03 ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCIRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGGEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNKGYCFHIVEINHKSLNTLQPMLFKTEIPKSCS 4wef A 2.50 BS03 SFJ A 1 L261 N262 T263 D264 L120 N121 T122 D123 Q6WJ03 ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCIRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGGEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNKGYCFHIVEINHKSLNTLQPMLFKTEIPKSCS 4wef A 2.50 BS04 SFJ A 2 R192 C214 Q215 R502 A528 N551 R51 C73 Q74 R361 A387 N410 Q6WJ03 ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCIRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGGEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNKGYCFHIVEINHKSLNTLQPMLFKTEIPKSCS 4wef A 2.50 BS06 FUC B 1 V187 D188 S554 L555 V46 D47 S413 L414 Q6WJ03 ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCIRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGGEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNKGYCFHIVEINHKSLNTLQPMLFKTEIPKSCS 4wef B 2.50 BS01 FUC A 1 S554 L555 S413 L414 Q6WJ03 ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCIRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGGEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNKGYCFHIVEINHKSLNTLQPMLFKTEIPKSCS 4wef B 2.50 BS04 SFJ B 1 K358 D362 Q365 A366 P370 E462 D471 G472 K217 D221 Q224 A225 P229 E321 D330 G331 Q6WJ03 ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCIRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGGEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNKGYCFHIVEINHKSLNTLQPMLFKTEIPKSCS 4wnd A 1.50 BS01 III B 1 L18 A21 L22 E25 D50 K52 T53 A56 S59 Q60 N63 Y67 D81 G93 K96 N100 N103 K106 H121 R136 Y139 N140 H146 R196 N200 N203 Y206 L207 R221 R235 R236 N240 N243 Q276 Y279 N283 T286 L287 R316 W319 L6 A9 L10 E13 D38 K40 T41 A44 S47 Q48 N51 Y55 D69 G81 K84 N88 N91 K94 H109 R124 Y127 N128 H134 R176 N180 N183 Y186 L187 R201 R215 R216 N220 N223 Q256 Y259 N263 T266 L267 R296 W299 P81274 25664792 MEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVG 4wne A 2.00 BS01 III B 1 A21 L22 E25 K52 T53 A56 I57 S59 Q60 N63 F66 Y67 H78 D81 G93 K96 N100 N103 K106 V107 H121 R136 Y139 N140 H146 K150 R196 N200 N203 Y206 L207 R221 R235 R236 N240 A10 L11 E14 K41 T42 A45 I46 S48 Q49 N52 F55 Y56 H67 D70 G82 K85 N89 N92 K95 V96 H110 R125 Y128 N129 H135 K139 R175 N179 N182 Y185 L186 R200 R214 R215 N219 P81274 25664792 SMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISRE 4wnf A 2.90 BS01 III B 1 A21 L22 E25 D50 S55 A56 Q60 N63 F66 H78 D81 G93 K96 N100 N103 K106 H121 R136 Y139 N140 H146 R196 N200 N203 Y206 L207 R221 R235 R236 N240 A10 L11 E14 D39 S44 A45 Q49 N52 F55 H67 D70 G82 K85 N89 N92 K95 H110 R125 Y128 N129 H135 R184 N188 N191 Y194 L195 R209 R223 R224 N228 P81274 25664792 SMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 4wng A 2.11 BS01 III B 1 L18 A21 L22 E25 T53 S55 A56 Q60 N63 F66 Y67 H78 D81 G93 K96 N100 N103 K106 V107 R136 Y139 H146 R196 N200 N203 L207 R221 R235 R236 N240 L8 A11 L12 E15 T43 S45 A46 Q50 N53 F56 Y57 H68 D71 G83 K86 N90 N93 K96 V97 R126 Y129 H136 R179 N183 N186 L190 R204 R218 R219 N223 P81274 25664792 GSMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISRE 4wua A 2.00 BS01 3UL A 1 L86 V145 F165 E166 V167 L168 G169 H170 L220 V223 Y227 L18 V77 F97 E98 V99 L100 G101 H102 L152 V155 Y159 2.7.11.1 Q96SB4 25993998 LVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATVNPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS 4x2a A 2.00 BS03 3WL A 1 H127 M158 E173 I180 A181 H113 M144 E159 I166 A167 4.4.1.5 Q9CPU0 26268338 TAFSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKIA 4x2a A 2.00 BS04 3WL B 1 Q34 L61 F63 F68 L70 F93 E100 Q20 L47 F49 F54 L56 F79 E86 4.4.1.5 Q9CPU0 26268338 TAFSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKIA 4x2a B 2.00 BS04 3WL B 1 H127 M158 E173 I180 I183 H120 M150 E165 I172 I175 4.4.1.5 Q9CPU0 26268338 SSGLTDETAFSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGMKGLAFIQDPDGYWIEILNPNKIATI 4x3n A 1.89 BS01 CA A 1 D144 N146 D148 R150 E155 D121 N123 D125 R127 E132 P24005 26327373 EKLSAEAMEFFCNVAKLPFSQQAVHFLNAYWAEVSKEAEFIYSVGWETIKYADMHCKGIQLVFKYDEGNDLDFDIALYFYEQLCKFCEDPKNKNYATTYPISQPQMLTALKRKQELREKVDVNFDGRVSFLEYLLYQYKDFANPADFCTRSMNHDEHPEIKKARLALEEVNKRIRAYEEEKARLTEESKIPGVKGLGATNMLAQIDSGPLKEQLNFALISAEAAVRTASKKYGGAAYSSAGAIWWMNRDLEEKKKRYGP 4xj0 A 2.58 BS01 41B A 1 E33 G34 G37 M38 V39 A52 K54 Q105 D106 M108 E109 T110 D111 K114 N154 L156 C166 D167 E22 G23 G26 M27 V28 A41 K43 Q94 D95 M97 E98 T99 D100 K103 N143 L145 C155 D156 2.7.11.24 P28482 25603482 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFELDDLPKEKLKELIFEETARFQPGYRS 4xj0 B 2.58 BS01 41B B 1 I31 E33 G34 G37 V39 A52 K54 I56 Q105 D106 M108 E109 T110 D111 K114 N154 L156 D167 I20 E22 G23 G26 V28 A41 K43 I45 Q94 D95 M97 E98 T99 D100 K103 N143 L145 D156 2.7.11.24 P28482 25603482 EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPG 4y62 A 1.60 BS02 48E A 1 F121 A122 I123 Y126 W181 S185 D211 V212 D213 H301 F57 A58 I59 Y62 W113 S117 D143 V144 D145 H233 2.4.1.40,2.4.1.37 P16442 SLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 4y63 A 1.30 BS02 48O A 1 F121 A122 I123 K124 Y126 W181 V184 R188 D211 V212 D213 F58 A59 I60 K61 Y63 W118 V121 R125 D148 V149 D150 2.4.1.40,2.4.1.37 P16442 VSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVP 4y64 A 1.60 BS02 48C A 1 F121 I123 Y126 V184 R188 D211 V212 D213 F58 I60 Y63 V121 R125 D148 V149 D150 2.4.1.40,2.4.1.37 P16442 VSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAV 4y86 A 2.01 BS01 49D A 1 M365 L420 L421 Y424 F441 M442 A452 Q453 F456 M181 L236 L237 Y240 F257 M258 A268 Q269 F272 3.1.4.35 O76083 26316540 KYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 4y8c A 2.70 BS01 49D A 1 M365 L420 L421 Y424 F425 F441 M442 A452 Q453 F456 M181 L236 L237 Y240 F241 F257 M258 A268 Q269 F272 3.1.4.35 O76083 26316540 KYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 4y8c B 2.70 BS01 49D B 1 M365 I403 L420 L421 Y424 F441 M442 A452 Q453 F456 M185 I223 L240 L241 Y244 F261 M262 A272 Q273 F276 3.1.4.35 O76083 26316540 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK 4ygx D 2.95 BS01 III E 1 D13 S14 S15 M17 N18 R19 K44 L45 P46 M85 N144 D10 S11 S12 M14 N15 R16 K41 L42 P43 M82 N141 3.1.3.-,3.1.3.16,3.1.3.41 Q9VWE4 26332362 PSKLAVAVVDSSNMNRSMEAHNFLAKKGFNVRSYGTGERVKLPGMAFDKPNVYEFGTKYEDIYRDLESKDKEFYTQNGLLHMLDRNRRIKKCPERFQDTKEQFDIIVTVEERVYDLVVMHMESMESVDNRPVHVLNVDVVNNAEDALMGAFVITDMINMMAKSTDLDNDIDELIQEFEERRKRVILHSVLFY 4yh1 A 2.20 BS01 III C 1 N96 D98 T152 A153 S154 L155 R178 K190 N20 D22 T76 A77 S78 L79 R102 K114 3.1.3.16 Q9GZU7 26332362 QYLLPEAKAQDSDKICVVINLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLR 4yh1 B 2.20 BS01 III D 1 N96 L97 D98 F106 V118 I120 T152 A153 S154 L155 Y158 R178 K190 N20 L21 D22 F30 V42 I44 T76 A77 S78 L79 Y82 R102 K114 3.1.3.16 Q9GZU7 26332362 QYLLPEAKAQDSDKICVVINLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLR 4yh5 A 1.90 BS01 ADP A 1 G22 T23 S24 D26 G188 G189 N217 D221 Y234 D235 K236 D237 G327 G328 Y331 E362 G12 T13 S14 D16 G178 G179 N207 D211 Y224 D225 K226 D227 G317 G318 Y321 E352 2.7.-.- B3VI55 VLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAG 4yh5 A 1.90 BS02 MN A 1 N186 E362 N176 E352 2.7.-.- B3VI55 VLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAG 4yh5 A 1.90 BS03 MN A 2 D26 D29 D16 D19 2.7.-.- B3VI55 VLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAG 4yv0 A 1.95 BS01 S4M A 1 Q40 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 G148 D149 G150 D168 T169 T170 Q27 L46 Q51 Y60 H61 G82 D85 V104 D105 I106 D107 V110 G135 D136 G137 D155 T156 T157 2.5.1.16 Q4DA73 26327378 GWFREEPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv0 A 1.95 BS02 4JW B 1 E14 M24 L26 W53 P235 T236 E5 M11 L13 W40 P210 T211 2.5.1.16 Q4DA73 26327378 GWFREEPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv0 B 1.95 BS01 S4M B 1 Q40 M57 L59 Q64 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Q36 M53 L55 Q60 H70 G91 D94 V113 D114 I115 D116 V119 D145 G146 D164 T165 T166 P171 A172 L175 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv0 B 1.95 BS02 4JW B 1 E14 Q22 A23 M24 T236 Y237 P238 C239 E10 Q18 A19 M20 T232 Y233 P234 C235 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv0 C 1.95 BS01 S4M C 1 Q40 M57 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 G148 D149 G150 D168 T169 T170 Q30 M47 L49 Q54 Y63 H64 G85 D88 V107 D108 I109 D110 V113 G138 D139 G140 D158 T159 T160 2.5.1.16 26327378 ISGGWFREEPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv0 C 1.95 BS02 4JW D 1 E14 M24 L26 W53 I63 P235 T236 E8 M14 L16 W43 I53 P214 T215 2.5.1.16 26327378 ISGGWFREEPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv0 D 1.95 BS02 4JW D 1 E14 W19 Q22 A23 M24 T236 Y237 P238 C239 E10 W15 Q18 A19 M20 T232 Y233 P234 C235 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv1 A 1.85 BS02 4K2 B 1 M24 L26 W53 P235 T236 M15 L17 W44 P214 T215 2.5.1.16 Q4DA73 26327378 GWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv1 B 1.85 BS01 S4M B 1 Q40 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 T170 P175 A176 L179 Q36 L55 Q60 Y69 H70 G91 D94 V113 D114 I115 D116 V119 D145 G146 D164 T165 T166 P171 A172 L175 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv1 B 1.85 BS02 4K2 B 1 E14 W19 Q22 M24 P238 C239 E10 W15 Q18 M20 P232 C233 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv1 D 1.85 BS02 4K2 D 1 E14 W19 Q22 M24 Y237 P238 C239 E10 W15 Q18 M20 Y231 P232 C233 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTTDPAGPASKLFAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv2 A 2.17 BS01 S4M A 1 Q40 L59 Q64 Y73 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 Q36 L55 Q60 Y69 H70 G91 D94 V113 D114 I115 D116 V119 D145 G146 D164 T165 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv2 A 2.17 BS02 4K3 B 1 M24 L26 W53 I63 P235 T236 M20 L22 W49 I59 P219 T220 2.5.1.16 Q4DA73 26327378 ELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv2 B 2.17 BS01 S4M B 1 Q40 M57 L59 Q64 V65 H74 G95 D98 V117 D118 I119 D120 V123 D149 G150 D168 T169 Q31 M48 L50 Q55 V56 H65 G86 D89 V108 D109 I110 D111 V114 D140 G141 D159 T160 2.5.1.16 Q4DA73 26327378 GWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv2 B 2.17 BS02 4K3 B 2 E14 M24 S25 L26 W53 I63 P235 E5 M15 S16 L17 W44 I54 P214 2.5.1.16 Q4DA73 26327378 GWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4yv2 B 2.17 BS03 4K3 B 1 Q22 M24 C239 Q13 M15 C218 2.5.1.16 Q4DA73 26327378 GWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDNTYDVVIIDTEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETGFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLKYYDSEMHKASFALPRFARHINN 4ywo A 1.62 BS01 FAD A 1 I7 G8 Y9 G10 A11 A12 G31 K32 G37 T38 C39 V42 G43 C44 S47 K48 G104 E105 A106 A129 T130 G131 N150 L171 R253 L259 G291 D292 M298 L299 E300 A303 F332 I11 G12 Y13 G14 A15 A16 G35 K36 G41 T42 C43 V46 G47 C48 S51 K52 G108 E109 A110 A133 T134 G135 N154 L175 R257 L263 G295 D296 M302 L303 E304 A307 F336 A4YG49 26217660 SQDPMHKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAREVTGSEVYPPFSSFQEKDGLVQEMRKTKYEDLLSYYDVELIQGEARFISPHAVKVNGQVIEAEKFVIATGSSPLIPRIPGLDKVGFWTNREALSPDRRIDSLAVIGGRALALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVKEVRKGAGKIVITDKGEVEADEILLATGRKPNVDLGLENAGVRLNERGGIKVDDELRTDNPHIYAAGDVLGGKMLEALAGRQGSIATENALTGSHKRVDENAVPQVIFTQPNLARVGLTEAEARAKEGEVEARVLPMSSVAKAEIINSRLGFVKMVTMNGRIVGVHAVGENVAEMIGEAALAIRFGATVHDLIDTVHMFPTIAESLRLVALAFRSD 4yy4 A 1.47 BS01 DMS A 1 F44 N100 Y106 F22 N78 Y84 Q9H8M2 TPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK 4yy6 A 1.45 BS01 III Z 1 H42 F44 F45 V49 I53 A54 P55 T98 Y99 N100 V105 Y106 H21 F23 F24 V28 I32 A33 P34 T77 Y78 N79 V84 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK 4yyd A 1.52 BS01 III Z 1 H42 F44 F45 I53 P55 I60 A96 T98 Y99 N100 V105 Y106 H20 F22 F23 I31 P33 I38 A74 T76 Y77 N78 V83 Y84 Q9H8M2 TPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK 4yyg A 2.10 BS01 III B 1 F44 F45 V49 I53 A54 P55 Y99 N100 Y106 F22 F23 V27 I31 A32 P33 Y77 N78 Y84 Q9H8M2 TPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yyh A 1.74 BS01 III Z 1 F44 F45 I53 P55 Y99 N100 Y106 F23 F24 I32 P34 Y78 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK 4yyh B 1.74 BS01 III Y 1 F44 F45 V49 I53 P55 A96 Y99 N100 Y106 F24 F25 V29 I33 P35 A76 Y79 N80 Y86 Q9H8M2 ESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK 4yyi A 1.50 BS01 III C 1 F44 V49 I53 P55 Y99 N100 Y106 F22 V27 I31 P33 Y77 N78 Y84 Q9H8M2 TPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yyi B 1.50 BS01 III C 1 F45 V49 I53 P55 N100 Y106 F23 V27 I31 P33 N78 Y84 Q9H8M2 TPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yyj A 1.85 BS01 III C 1 F44 F45 V49 I53 P55 Y99 N100 Y106 F23 F24 V28 I32 P34 Y78 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yyk B 1.79 BS01 III C 1 F45 I53 P55 Y99 N100 Y106 F24 I32 P34 Y78 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yyk D 1.79 BS01 III F 1 F44 F45 I53 A54 P55 Y99 N100 Y106 F23 F24 I32 A33 P34 Y78 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yyk E 1.79 BS01 III F 1 F45 V49 I53 P55 A96 N100 Y106 F24 V28 I32 P34 A75 N79 Y85 Q9H8M2 STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMS 4yym A 1.50 BS01 III Z 1 P1527 F1528 V1532 F1536 Y1540 Y1582 N1583 Y1589 P28 F29 V33 F37 Y41 Y83 N84 Y90 P21675 DDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAEL 4yym B 1.50 BS01 III Z 1 P1527 F1528 V1532 Y1540 K1581 Y1582 N1583 G1584 Y1589 P28 F29 V33 Y41 K82 Y83 N84 G85 Y90 P21675 DDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELE 4yyn A 1.85 BS01 III Z 1 P1527 F1528 H1530 V1532 F1536 D1539 K1542 M1548 K1581 Y1582 N1583 Y1589 P27 F28 H30 V32 F36 D39 K42 M48 K81 Y82 N83 Y89 P21675 DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAE 4yyn B 1.85 BS01 III Z 1 D1524 W1526 P1527 F1528 V1532 F1536 V1537 M1548 N1583 Y1589 D23 W25 P26 F27 V31 F35 V36 M47 N82 Y88 P21675 DDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEA 4z3a A 1.72 BS01 NUC C 1 G105 S106 H107 A109 S110 P155 K201 K246 A274 R275 A277 P280 R281 G1 S2 H3 A5 S6 P51 K97 K142 A170 R171 A173 P176 R177 3.2.2.29 Q13569 GSHMASFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKG 4z3a A 1.72 BS02 NUC D 1 G105 I139 N140 G142 N157 G199 S200 K201 G231 K232 C233 P270 S271 S273 A274 R275 C276 A277 Q278 G1 I35 N36 G38 N53 G95 S96 K97 G127 K128 C129 P166 S167 S169 A170 R171 C172 A173 Q174 3.2.2.29 Q13569 GSHMASFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKG 4z47 A 1.45 BS02 NUC D 1 I139 N140 N157 S200 K201 G231 K232 C233 F252 P270 S271 S273 A274 R275 C276 A277 Q278 I29 N30 N47 S90 K91 G121 K122 C123 F142 P160 S161 S163 A164 R165 C166 A167 Q168 3.2.2.29 Q13569 FNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERNM 4z7b A 2.02 BS01 NUC C 1 P155 A274 R275 A277 P280 R281 P45 A164 R165 A167 P170 R171 3.2.2.29 Q13569 FNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIE 4z90 A 3.00 BS01 4LE A 1 L240 A244 L231 A235 E0SJQ4 26346220 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIR 4z90 F 3.00 BS01 4LE F 1 T237 L240 T228 L231 E0SJQ4 26346220 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIR 4z91 B 3.39 BS01 4LJ B 1 E77 F78 P85 E68 F69 P76 E0SJQ4 26346220 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIR 4z91 C 3.39 BS01 4LJ C 1 E77 F78 V81 E68 F69 V72 E0SJQ4 26346220 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIR 4z91 E 3.39 BS02 4LJ E 1 F78 P85 F69 P76 E0SJQ4 26346220 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIR 4z91 H 3.39 BS01 4LJ H 1 R91 N103 R82 N94 E0SJQ4 26346220 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRCRLAFPLGFLAIGCVLVIR 4zhl U 2.06 BS01 III P 1 Y40 V41 C42 H57 C58 A96 D97 T97A L97B A98 Y99 Y151 D189 S190 C191 Q192 G193 S195 W215 G216 R217 G219 C220 G226 Y29 V30 C31 H46 C47 A89 D90 T91 L92 A93 Y94 Y150 D192 S193 C194 Q195 G196 S198 W218 G219 R220 G221 C222 G229 3.4.21.73 P00749 26281711 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAYHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKE 4zhm U 1.90 BS01 III P 1 V41 H57 C58 A96 D97 T97A L97B Y99 Y151 Q192 G193 W215 G216 R217 V30 H46 C47 A89 D90 T91 L92 Y94 Y150 Q195 G196 W218 G219 R220 3.4.21.73 P00749 26281711 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAYHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKE 4zhm U 1.90 BS02 MRZ P 1 D189 S190 C191 V213 W215 G216 G219 C220 G226 D192 S193 C194 V216 W218 G219 G221 C222 G229 3.4.21.73 P00749 26281711 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAYHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKE 4zlu A 1.80 BS02 4PW A 1 R153 P165 I190 N192 D212 R144 P156 I181 N183 D203 2.7.-.- B3VI55 NVLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAGS 4zlu B 1.80 BS01 ADP B 1 G22 T23 S24 D26 G188 G189 N217 D221 Y234 G327 G328 Y331 E362 G13 T14 S15 D17 G179 G180 N208 D212 Y225 G318 G319 Y322 E353 2.7.-.- B3VI55 NVLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAGSH 4zlu B 1.80 BS02 4PW B 1 R153 P165 N186 I190 N192 D212 T268 E362 R144 P156 N177 I181 N183 D203 T259 E353 2.7.-.- B3VI55 NVLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAGSH 4zrm A 1.90 BS01 NAD A 1 G7 A9 G10 F11 I12 D31 N32 S34 S35 G36 Q50 S51 I52 L73 A74 A75 A77 T92 S116 Y143 K147 Y170 A171 V173 E183 G7 A9 G10 F11 I12 D31 N32 S34 S35 G36 Q50 S51 I52 L73 A74 A75 A77 T92 S116 Y143 K147 Y170 A171 V173 E183 5.1.3.2 Q9WYX9 26344854 MNILVTGGAGFIGSHVVDKLIENGYGVIVVDNLSSGKVENLNRNALFYEQSIEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEKSIKYGVKKFIFSSTGGAIYGENVKVFPTPETEIPHPISPYGIAKYSTEMYLEFFAREYGLKYTVLRYANVYGPRQDPYGEAGVVAIFTERMLRGEEVHIFGDGEYVRDYVYVDDVVRANLLAMEKGDNEVFNIGTGRGTTVNQLFKLLKEITGYDKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEEGLKLTVEYFRKTL 4zrm B 1.90 BS01 NAD B 1 G7 A9 G10 F11 I12 D31 N32 L33 S34 S35 G36 Q50 S51 I52 E53 L73 A74 A75 A77 T92 S115 S116 Y143 K147 Y170 A171 V173 E183 A184 G8 A10 G11 F12 I13 D32 N33 L34 S35 S36 G37 Q51 S52 I53 E54 L74 A75 A76 A78 T93 S116 S117 Y144 K148 Y171 A172 V174 E184 A185 5.1.3.2 Q9WYX9 26344854 HMNILVTGGAGFIGSHVVDKLIENGYGVIVVDNLSSGKVENLNRNALFYEQSIEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEKSIKYGVKKFIFSSTGGAIYGENVKVFPTPETEIPHPISPYGIAKYSTEMYLEFFAREYGLKYTVLRYANVYGPRQDPYGEAGVVAIFTERMLRGEEVHIFGDGEYVRDYVYVDDVVRANLLAMEKGDNEVFNIGTGRGTTVNQLFKLLKEITGYDKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEEGLKLTVEYFRKT 4zrn A 2.00 BS01 NAD A 1 G7 A9 G10 F11 I12 D31 N32 S34 S35 G36 Q50 S51 I52 E53 L73 A74 A75 T92 S115 S116 Y143 K147 Y170 A171 V173 G7 A9 G10 F11 I12 D31 N32 S34 S35 G36 Q50 S51 I52 E53 L73 A74 A75 T92 S115 S116 Y143 K147 Y170 A171 V173 5.1.3.2 Q9WYX9 26344854 MNILVTGGAGFIGSHVVDKLIENGYGVIVVDNLSSGKVENLNRNALFYEQSIEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEKSIKYGVKKFIFSSTGGAIYGENVKVFPTPETEIPHPISPYGIAKYSTEMYLEFFAREYGLKYTVLRYANVYGPRQDPYGEAGVVAIFTERMLRGEEVHIFGDGEYVRDYVYVDDVVRANLLAMEKGDNEVFNIGTGRGTTVNQLFKLLKEITGYDKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEEGLKLTVEYFRKTLE 4zrn A 2.00 BS02 UPG A 1 V79 T117 G119 A120 Y143 N172 G185 V186 H201 I202 F203 Y208 R210 V244 R267 D270 V79 T117 G119 A120 Y143 N172 G185 V186 H201 I202 F203 Y208 R210 V244 R267 D270 5.1.3.2 Q9WYX9 26344854 MNILVTGGAGFIGSHVVDKLIENGYGVIVVDNLSSGKVENLNRNALFYEQSIEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEKSIKYGVKKFIFSSTGGAIYGENVKVFPTPETEIPHPISPYGIAKYSTEMYLEFFAREYGLKYTVLRYANVYGPRQDPYGEAGVVAIFTERMLRGEEVHIFGDGEYVRDYVYVDDVVRANLLAMEKGDNEVFNIGTGRGTTVNQLFKLLKEITGYDKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEEGLKLTVEYFRKTLE 4zrn B 2.00 BS02 UPG B 1 A77 T117 Y143 N172 A184 G185 V186 H201 I202 F203 Y208 R210 V244 R267 D270 A77 T117 Y143 N172 A184 G185 V186 H201 I202 F203 Y208 R210 V244 R267 D270 5.1.3.2 Q9WYX9 26344854 MNILVTGGAGFIGSHVVDKLIENGYGVIVVDNLSSGKVENLNRNALFYEQSIEDEEMMERIFSLHRPEYVFHLAAQASVAISVREPARDAKTNIIGSLVLLEKSIKYGVKKFIFSSTGGAIYGENVKVFPTPETEIPHPISPYGIAKYSTEMYLEFFAREYGLKYTVLRYANVYGPRQDPYGEAGVVAIFTERMLRGEEVHIFGDGEYVRDYVYVDDVVRANLLAMEKGDNEVFNIGTGRGTTVNQLFKLLKEITGYDKEPVYKPPRKGDVRKSILDYTKAKEKLGWEPKVSLEEGLKLTVEYFRKTL 5a1m A 1.81 BS01 CA A 1 E280 E281 E305 E34 E35 E59 Q9Y6U3 KMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDK 5ae8 A 2.42 BS01 VVX A 1 T750 M752 W760 I777 K779 D787 Y813 I825 E826 V827 V828 D832 T833 M900 I910 D911 T583 M585 W593 I610 K612 D620 Y646 I658 E659 V660 V661 D665 T666 M733 I743 D744 Q3UDT3 26301626 RVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSANRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRITEEEQLQLREILERELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVN 5ae9 A 2.44 BS01 OKO A 1 M752 S754 W760 I777 K779 L784 D787 I825 E826 V827 V828 D832 T833 M900 I910 D911 M587 S589 W595 I612 K614 L619 D622 I660 E661 V662 V663 D667 T668 M735 I745 D746 Q3UDT3 26301626 RVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRITEEEQLQLREILERELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVN 5aeb A 2.10 BS01 ZN A 1 D120 H121 H263 D82 H83 H221 3.5.2.6 B5L5V5 VKEPTVSNADWSKPYRPFRIAGNLYYIGTYDLACYLITTKQGNIIVNTGLAASALQIKNNIKALGFKLTDTKILLTTQAHYDHLGAMAEIKKITGAKLMADEGDATVMADGGSSDYAFGGHGSMFEPIIADRLLHDKDTIQLGDTKLVMLHHPGHTKGSCSFLFDTKDEQRSYRILIANMPTIVIEKKFSEVSSYPGIAKDYAYTLQAMKNLSFDIWVASHASQFSMHSKHKPGDGYNPKSFMDRKGYDESLDKLQKEYEKHLN 5aeb A 2.10 BS02 ZN A 2 Q116 H118 H196 Q78 H80 H155 3.5.2.6 B5L5V5 VKEPTVSNADWSKPYRPFRIAGNLYYIGTYDLACYLITTKQGNIIVNTGLAASALQIKNNIKALGFKLTDTKILLTTQAHYDHLGAMAEIKKITGAKLMADEGDATVMADGGSSDYAFGGHGSMFEPIIADRLLHDKDTIQLGDTKLVMLHHPGHTKGSCSFLFDTKDEQRSYRILIANMPTIVIEKKFSEVSSYPGIAKDYAYTLQAMKNLSFDIWVASHASQFSMHSKHKPGDGYNPKSFMDRKGYDESLDKLQKEYEKHLN 5aeb A 2.10 BS03 CO A 1 E140 H175 E102 H135 3.5.2.6 B5L5V5 VKEPTVSNADWSKPYRPFRIAGNLYYIGTYDLACYLITTKQGNIIVNTGLAASALQIKNNIKALGFKLTDTKILLTTQAHYDHLGAMAEIKKITGAKLMADEGDATVMADGGSSDYAFGGHGSMFEPIIADRLLHDKDTIQLGDTKLVMLHHPGHTKGSCSFLFDTKDEQRSYRILIANMPTIVIEKKFSEVSSYPGIAKDYAYTLQAMKNLSFDIWVASHASQFSMHSKHKPGDGYNPKSFMDRKGYDESLDKLQKEYEKHLN 5bn3 A 2.00 BS01 ADP A 1 G226 S227 G228 K229 T230 V231 Y414 Q491 D492 A493 F494 G226 S227 G228 K229 T230 V231 Y414 Q489 D490 A491 F492 3.6.3.14 Q74MJ7 MNRIISINGPLVIAKGKFSIFEVVRVGEEKLIGEVIGIENDKAYIQVYEDTNGLKVGEPVFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIPKGIDLPTLDRKKVWEFIPKKKKGDTIKGGDIIGTVNENGFEHRIIVPPNVEGKIEEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGALSDNEKIYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHKYYVTVKQLLGIPLEEIEQKGIHEKIIKLRYKSLKEFREEIKAIEQEILSL 5bn3 A 2.00 BS02 MG A 1 T230 R253 T230 R253 3.6.3.14 Q74MJ7 MNRIISINGPLVIAKGKFSIFEVVRVGEEKLIGEVIGIENDKAYIQVYEDTNGLKVGEPVFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIPKGIDLPTLDRKKVWEFIPKKKKGDTIKGGDIIGTVNENGFEHRIIVPPNVEGKIEEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGALSDNEKIYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHKYYVTVKQLLGIPLEEIEQKGIHEKIIKLRYKSLKEFREEIKAIEQEILSL 5bn3 A 2.00 BS03 MG A 2 G216 V315 S372 T374 G216 V315 S372 T374 3.6.3.14 Q74MJ7 MNRIISINGPLVIAKGKFSIFEVVRVGEEKLIGEVIGIENDKAYIQVYEDTNGLKVGEPVFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIPKGIDLPTLDRKKVWEFIPKKKKGDTIKGGDIIGTVNENGFEHRIIVPPNVEGKIEEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGALSDNEKIYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHKYYVTVKQLLGIPLEEIEQKGIHEKIIKLRYKSLKEFREEIKAIEQEILSL 5bn3 B 2.00 BS01 MG B 1 R92 D93 R90 D91 Q74MS5 PSIKPPLIAVELENPMLGEVIDLEETKAIVIAAYENKALALLFDYYTGEIQINRQGNTYKIAVSEDYIGGIFNGFGEPIKGPKPYPEDYRDINGLAINPYARKVPNEILYTGISSIDVAHPLLKGQKIAIFSPPGLPMERLALQIARNVAKDKTIIFAAIGVPSDIYKMFIDEFINTKAIMNSAIFISKADSSPIEKIYTPRVALTLAEYLAFEKNRDVLVLMLDMTNYADALREISTLRKEIPSRRGYPAYLYTDLASIYERSGLTSKGSITLIPMLTMPGNDITHVVPDLTGYITEGQYVLSQDLHSKNIYPPIDLLKSLSRLAKNGMSKKHKKYADILIKSYAKGLEARDIATIVGELSKEDKAYLKFAELVEKEFIKQDYYEYRSIEKSFEIIDSILSQSGLP 5bn4 A 2.70 BS01 ANP A 1 P224 F225 G226 S227 G228 K229 T230 V231 R253 E256 D320 Y414 Q491 D492 A493 F494 P224 F225 G226 S227 G228 K229 T230 V231 R253 E256 D320 Y414 Q491 D492 A493 F494 3.6.3.14 Q74MJ7 MNRIISINGPLVIAKGKFSIFEVVRVGEEKLIGEVIGIENDKAYIQVYEDTNGLKVGEPVFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIPKGIDLPTLDRKKVWEFIPKKKKGDTIKGGDIIGTVNENGFEHRIIVPPNVEGKIEEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGPDALSDNEKIYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHKYYVTVKQLLGKIPLEEIEQKGIHEKIIKLRYKSLKEFREEIKAIEQEILSLL 5bn4 A 2.70 BS02 MG A 1 T230 E252 R253 E256 T230 E252 R253 E256 3.6.3.14 Q74MJ7 MNRIISINGPLVIAKGKFSIFEVVRVGEEKLIGEVIGIENDKAYIQVYEDTNGLKVGEPVFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIPKGIDLPTLDRKKVWEFIPKKKKGDTIKGGDIIGTVNENGFEHRIIVPPNVEGKIEEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGPDALSDNEKIYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHKYYVTVKQLLGKIPLEEIEQKGIHEKIIKLRYKSLKEFREEIKAIEQEILSLL 5bo5 A 2.81 BS01 MG A 1 G137 T281 G123 T267 Q74MS5 KPPLIAVELENPMLGEVIDLETKAIVIAAYENKALALLFDYYTGINRQGNTYKIAVSEDYIGGIFNGFGEPIKGPKPYPEDYRDINGLARKVPNEILYTGISSIDVAHPLLKGQKIAIFSPPGLPMERLALQIARNVAKDKTIIFAAIGVPSDIYKMFIDEFINTKAIMNSAIFISKADSSPIEKIYTPRVALTLAEYLAFEKNRDVLVLMLDMTNYADALREISTLRKEIPSRRGYPAYLYTDLASIYERSGLTSKGSITLIPMLTMPGNDITHVVPDLTGYITEGQYVLSQDLHSKNIYPPIDLLKSLSRLAKNGMSKKHKKYADILIKSYAKGLEARDIATIVGEDSLSKEDKAYLKFAELVEKEFIKQDYYEYRSIEKSFEIIDSILSQSGLP 5bo5 B 2.81 BS01 MG B 1 H122 S323 H104 S304 Q74MS5 PPLIAVELENPMLGEVIDLEETKAIVIAAYENKALALLFDYTNRQGNTYKIAVSEDYIGGIFNGFGEPIKGPKPYPEDYRDINGARKVPNEILYTGISSIDVAHPLLKGQKIAIFSPPGLPMERLALQIARNVAKDKTIIFAAIGVPSDIYKMFIDEFINTKAIMNSAIFISKADSSPIEKIYTPRVALTLAEYLAFEKNRDVLVLMLDMTNYADALREISTLRKEIPSRRGYPAYLYTDLASIYERSGLTKGSITLIPMLTMPGNDITHVVPDLTGYITEGQYVLSQDLHSKNIYPPIDLLKSLSRLAKNGMSKKHKKYADILIKSYAKGLEARDIATIVGEDSLSKEDKAYLKFAELVEKEFIKQDYYEYRSIEKSFEIIDSILSQSGLP 5bsb A 1.85 BS01 4PW A 1 R153 A164 P165 I190 N192 D212 R144 A155 P156 I181 N183 D203 2.7.-.- B3VI55 NVLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAGSH 5bvc A 2.00 BS02 4PW A 1 R153 P165 I190 N192 D212 T268 E362 R144 P156 I181 N183 D203 T259 E353 2.7.-.- B3VI55 NVLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAGSH 5bvc A 2.00 BS03 MG A 1 G22 D26 G13 D17 2.7.-.- B3VI55 NVLDFTVLGLNSGTSMDGIDCALCHFYQKTPDAPMEFELLEYGEVPLAQPIKQRVMRMILEDTTSPSELSEVNVILGEHFADAVRQFAAERNVDLSTIDAIASHGQTIWLLSMPEEGQVKSALTMAEGAILASRTGITSITDFRISDQAAGRQGAPLIAFFDALLLHHPTKLRACQNIGGIANVCFIPPDVDGRRTDEYYDFDTGPGNVFIDAVVRHFTNGEQEYDKDGAMGKRGKVDQELVDDFLKMPYFQLDPPKTTGREVFRDTLAHDLIRRAEAKGLSPDDIVATTTRITAQAIVDHYRRYAPSQEIDEIFMCGGGAYNPNIVEFIQQSYPNTKIMMLDEAGVPAGAKEAITFAWQGMEALVGRSIPVPTRVETRQHYVLGKVSPGLNYRSVMKKGMAFGGDAQQLPWVSEMIVKKKGKVITNNWAGSH 5c03 A 1.90 BS01 AGS A 1 L595 G598 T599 T601 V603 V640 K642 E688 Y689 V690 P694 N734 R738 N739 L741 P760 G761 L17 G20 T21 T23 V25 V36 K38 E84 Y85 V86 P90 N130 R134 N135 L137 P156 G157 2.7.10.2 P29597 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 5c0q A 2.50 BS01 ZN A 1 D117 H161 H165 D114 H151 H155 3.2.1.52 Q9AG27 26187666 DLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSELRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5c0q A 2.50 BS02 ZN A 2 D171 H173 D161 H163 3.2.1.52 Q9AG27 26187666 DLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSELRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5c0q A 2.50 BS03 ZN A 3 E185 E189 E175 E179 3.2.1.52 Q9AG27 26187666 DLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSELRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5c0q A 2.50 BS04 ZN A 4 R54 E327 E330 R51 E317 E320 3.2.1.52 Q9AG27 26187666 DLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSELRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5c0q A 2.50 BS06 ZN A 6 E334 H448 E324 H431 3.2.1.52 Q9AG27 26187666 DLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSELRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5c0q A 2.50 BS07 ZN A 7 H161 D245 H151 D235 3.2.1.52 Q9AG27 26187666 DLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSELRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5c0q B 2.50 BS07 ZN B 6 E286 K289 E283 K286 3.2.1.52 Q9AG27 26187666 DVDLGKLFFCGFDDFNEEAREVIQKYRPAGVLIYPGVLSKEYLFLDFMNFLSRNGRFIVSSDHEGGQLEVLKYVPSFPGNLAAGKVDPVFTGRYCEMAGRIMNTLGFNMVFAPVLDLLSEKGSVDLRSFGSDPEVVASHGMEACMGYFKGGVIPCIKHFPGHGKTADDSHYLLPTVNASFEELWREDLLPFRRIFQSRVKTAVMTAHVKYPAVDDLPATLSKKLITEVLREKLNFKGLVLSDAMEMKAISENFSVEEAVRFFIEAGGNMILLDNFRDLPVYYESLKKLIEDGSIERGKVERSIKIVDEYLSALENRFNSGLIAEVAERAIECTRMRKELLGREVVLLVPSNTTGDDYDLIPEVAKRFFKVRDVIRYDIEAGPDDVDGELIFDFVVNASKNEQVLQAHLSLPSDRTIYFIIRNPFDAKFFPGRSVVITHSTKPISVYKSFQHLLGRCS 5ca8 A 2.30 BS01 MG A 1 S72 D123 E125 S46 D87 E89 3.6.5.5 Q9C0L9 DAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5ca8 A 2.30 BS02 GDP A 1 S68 T69 G70 K71 S72 T73 V85 M86 E125 W158 R204 D205 H254 K255 S42 T43 G44 K45 S46 T47 V59 M60 E89 W117 R163 D164 H213 K214 3.6.5.5 Q9C0L9 DAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMGIWLAYSPVVSTTLGHTTSKSNILVMDVEGTDEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLIVIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFKPEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKGVYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFAVAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV 5cmv A 1.80 BS01 HEM A 1 T39 K42 F43 K45 H64 V67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 F138 T39 K42 F43 K45 H64 V67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 F138 P68082 GLSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGTVVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSKHPGDFGADAQGAMTKALELFRNDIAAKYKELGFQ 5cvj D 1.80 BS01 SAH D 1 W166 F179 M183 S187 G211 G213 D234 L235 V238 D254 M255 K268 I270 D273 W274 W159 F172 M176 S180 G204 G206 D227 L228 V231 D247 M248 K261 I263 D266 W267 2.1.1.146 O04385 EIQIIPTHSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKTA 5cvj D 1.80 BS02 N7I D 1 F130 L133 A134 I165 W166 F179 M183 W269 H272 D273 M323 Y326 N327 F123 L126 A127 I158 W159 F172 M176 W262 H265 D266 M316 Y319 N320 2.1.1.146 O04385 EIQIIPTHSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKTA 5cvj A 1.80 BS01 SAH A 1 W166 F179 M183 S187 G211 D234 L235 V238 D254 M255 F256 K268 W269 I270 D273 W160 F173 M177 S181 G205 D228 L229 V232 D248 M249 F250 K262 W263 I264 D267 2.1.1.146 O04385 AEIQIIPTHSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKT 5cvj A 1.80 BS02 N7I A 1 L133 A134 L139 I165 W166 F179 M183 W269 H272 D273 L322 M323 Y326 N327 L127 A128 L133 I159 W160 F173 M177 W263 H266 D267 L316 M317 Y320 N321 2.1.1.146 O04385 AEIQIIPTHSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKT 5cvj B 1.80 BS02 N7I B 1 A134 I165 W166 M183 W269 H272 D273 L322 M323 Y326 N327 A120 I151 W152 M169 W255 H258 D259 L308 M309 Y312 N313 2.1.1.146 O04385 HSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKTA 5cvu A 1.80 BS01 55B A 1 A134 I165 W166 F179 W269 H272 D273 T319 L322 M323 Y326 N327 A120 I151 W152 F165 W255 H258 D259 T305 L308 M309 Y312 N313 2.1.1.146 O04385 HSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKTA 5cvv A 1.73 BS02 N7I A 1 L133 L139 I165 W166 F179 M183 W269 H272 D273 M319 M323 Y326 N327 L118 L124 I150 W151 F164 M168 W254 H257 D258 M304 M308 Y311 N312 2.1.1.146 O04385 SSDEEANLFAHQLARAASLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSGVEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHMDALMLAYNPGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKTA 5cw3 A 2.55 BS01 ZN A 1 H94 H96 D107 H92 H94 D105 E2AXC7 26344097 DSSLQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRVEISSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFVGLIFSVFSEGKESKEHEIFLNCFQSDNGEATEIPLEIVHTPDISDRCLRTMTDLSKILVQEEEDMAEACKDHPDVLASIHNNAVRTRALIHITDIITKPLVQTFEKRIALNKLRATHLQRQLQELQKM 5cw3 C 2.55 BS01 ZN C 1 E30 H94 H96 D107 E25 H84 H86 D97 E2AXC7 26344097 LQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRDKKKDSSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFVGLIFSVFSEGKESKEHEIFLNCFQSDNEATEIPLEIVHTPDISDRCLRTMTDLSKILVQEEEDMAEACKDHPDVLASIHNNAVRTRALIHITDIITKPLVQTFEKRIALNKLRATHLQRQLQELQKM 5cw6 A 3.19 BS01 ZN A 1 H92 H94 D105 H83 H85 D96 26344097 MAVNAVHLESDAFLVCMNHALSTEEVMGLCIGEVDTNRIVHIHSVIILRRVEISPEQLSAASTEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSVGSEYERIEIPIHVV 5cxz A 1.70 BS01 55U A 1 L377 V385 A400 V433 M448 E449 M450 A451 E452 G454 P455 R498 N499 L501 D512 L15 V23 A38 V66 M81 E82 M83 A84 E85 G87 P88 R131 N132 L134 D145 2.7.10.2 P43405 26320624 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVTDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNHH 5cyi A 2.00 BS01 55S A 1 I10 E12 V18 A31 V64 F80 E81 L83 H84 Q85 D86 K89 N132 L134 I11 E13 V19 A32 V65 F81 E82 L84 H85 Q86 D87 K90 N133 L135 2.7.11.22 P24941 26320860 SMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 5cyi C 2.00 BS01 55S C 1 I10 G11 E12 G13 A31 V64 F80 E81 F82 L83 H84 Q85 D86 K89 N132 L134 I11 G12 E13 G14 A32 V65 F81 E82 F83 L84 H85 Q86 D87 K90 N133 L135 2.7.11.22 P24941 26320860 SMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 5cys A 2.45 BS01 NUC C 1 A109 S110 P155 A274 R275 A277 P280 R281 A1 S2 P47 A166 R167 A169 P172 R173 3.2.2.29 Q13569 ASFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERN 5d6t A 1.93 BS01 NGA A 1 Y65 Y126 F164 D166 N202 E222 Y288 Y14 Y75 F113 D115 N151 E171 Y237 A1CJQ5 26342082 HMMGPKSKVFVPLYVYPAPGAWDPLEDVISKHPDVNFTVVINPGSGPGPEALPDGNYTREIPKLASYENVRLLGYVATTYAKRNISEVRRDIETYAAWPTQSSNANLAVRGIFFDETPQQYDADILAYLRELTDVVKGTSGLGPDHYVVHNPGAIPDSRYLSTADSTVVFEATYATFQERHGAELFDTIPDSHRDQLCAVIHSVPTSVEGSDLRGLVKQVRQVADEIFITHLETDYYAGFGGQWSEFVDLMAS 5dd7 A 1.70 BS01 ANP A 1 F4 I7 F11 I23 G24 D25 D26 L84 G116 G117 D118 T119 F4 I7 F11 I23 G24 D25 D26 L84 G116 G117 D118 T119 2.7.4.16 A0A0D5YC82 MAEFSIIDQYFNRQSHPDVALGIGDDSALITPPPNQQLVICADTLVAGRHFPLETSPHAIGWKSVAVNLSDIAAMGAKPHSILLAISLPQVDHEWLEGFSQGIYDCCNQFGVALIGGDTTQGPHLTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQIGDAAYGLQHLGHSLQQRLDYPTPRCKLGEELKGLASSMIDVSDGLAQDLGHILKASKVGARLILEKLPVDPVLQQIEEQQRWQYALAGGDDYELCFTITPQNYEKLLQKQLDVKITMIGQIVEQTKLTFEHLGSDYPLQIHGYQHFA 5dd7 A 1.70 BS02 TPS A 1 G48 R49 H50 F51 P52 L165 L176 S200 D201 G246 D248 Y301 H303 G48 R49 H50 F51 P52 L165 L176 S200 D201 G246 D248 Y301 H303 2.7.4.16 A0A0D5YC82 MAEFSIIDQYFNRQSHPDVALGIGDDSALITPPPNQQLVICADTLVAGRHFPLETSPHAIGWKSVAVNLSDIAAMGAKPHSILLAISLPQVDHEWLEGFSQGIYDCCNQFGVALIGGDTTQGPHLTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQIGDAAYGLQHLGHSLQQRLDYPTPRCKLGEELKGLASSMIDVSDGLAQDLGHILKASKVGARLILEKLPVDPVLQQIEEQQRWQYALAGGDDYELCFTITPQNYEKLLQKQLDVKITMIGQIVEQTKLTFEHLGSDYPLQIHGYQHFA 5dei A 1.30 BS04 MG A 2 L496 K497 L494 K495 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dei A 1.30 BS07 BCT C 1 H282 L462 F465 H280 L460 F463 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dei A 1.30 BS08 TDP C 1 N24 P25 G26 E48 H71 A74 G75 N78 N22 P23 G24 E46 H69 A72 G73 N76 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dei B 1.30 BS07 BCT D 1 H282 L462 H280 L460 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dei D 1.30 BS02 BCT B 1 H282 F465 H280 F463 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGALRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dep A 2.16 BS01 UD1 B 1 I130 I148 F166 N194 E196 R200 R201 I130 I148 F166 N194 E196 R200 R201 2.3.1.129 A6V1E4 26352800 MSLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep A 2.16 BS02 UD1 B 2 L3 D5 R7 L3 D5 R7 2.3.1.129 A6V1E4 26352800 MSLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep B 2.16 BS01 UD1 B 1 D70 L71 K72 H121 H140 H156 Q157 Y158 D69 L70 K71 H120 H139 H155 Q156 Y157 2.3.1.129 A6V1E4 26352800 SLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep B 2.16 BS02 UD1 B 3 I9 D11 G29 A30 E31 K47 G48 D67 R96 I8 D10 G28 A29 E30 K46 G47 D66 R95 2.3.1.129 A6V1E4 26352800 SLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep D 2.16 BS01 UD1 D 1 H128 W146 H164 R201 G202 F203 S204 E241 H128 W146 H164 R201 G202 F203 S204 E241 2.3.1.129 A6V1E4 26352800 MSLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep D 2.16 BS02 UD1 F 1 M114 I130 I148 F166 N194 E196 R200 R201 M114 I130 I148 F166 N194 E196 R200 R201 2.3.1.129 A6V1E4 26352800 MSLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep E 2.16 BS01 UD1 E 1 D70 K72 H121 Q157 D69 K71 H120 Q156 2.3.1.129 A6V1E4 26352800 SLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep F 2.16 BS01 UD1 E 1 I148 F166 N194 E196 R200 I146 F164 N192 E194 R198 2.3.1.129 A6V1E4 26352800 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep F 2.16 BS02 UD1 F 1 D70 L71 K72 H121 H140 Q157 Y158 D68 L69 K70 H119 H138 Q155 Y156 2.3.1.129 A6V1E4 26352800 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dep F 2.16 BS03 UD1 F 3 I9 D11 I27 G29 A30 K47 G48 D67 R96 I7 D9 I25 G27 A28 K45 G46 D65 R94 2.3.1.129 A6V1E4 26352800 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dg3 A 2.30 BS01 U21 B 1 M114 I130 V132 N133 G151 F166 N194 E196 G197 R200 M112 I128 V130 N131 G149 F164 N192 E194 G195 R198 2.3.1.129 A6V1E4 26352800 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dg3 B 2.30 BS01 U21 B 1 D70 L71 K72 H118 H121 A136 A138 H140 V155 H156 Q157 Y158 D69 L70 K71 H117 H120 A135 A137 H139 V154 H155 Q156 Y157 2.3.1.129 A6V1E4 26352800 SLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dg3 B 2.30 BS02 U21 C 1 M114 V132 N133 I148 G151 F166 N194 E196 G197 R200 M113 V131 N132 I147 G150 F165 N193 E195 G196 R199 2.3.1.129 A6V1E4 26352800 SLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dg3 C 2.30 BS01 U21 C 1 P69 D70 L71 K72 H118 H121 A136 A138 H140 V155 Q157 P67 D68 L69 K70 H116 H119 A134 A136 H138 V153 Q155 2.3.1.129 A6V1E4 26352800 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dg3 D 2.30 BS01 U21 D 1 M114 I130 V132 N133 I148 F166 N194 E196 G197 R200 M105 I121 V123 N124 I139 F157 N185 E187 G188 R191 2.3.1.129 A6V1E4 26352800 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQSATRGITR 5dgd A 1.13 BS01 MG A 1 A133 P136 A167 D168 S171 A132 P135 A166 D167 S170 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGVLRWIAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dgd A 1.13 BS05 TDP A 1 T377 S378 G401 L403 G427 D428 G429 S430 Y433 N455 T457 Y458 G459 V460 L461 T376 S377 G400 L402 G426 D427 G428 S429 Y432 N454 T456 Y457 G458 V459 L460 4.1.1.7 P20906 ASVHGTTYELLRRQGIDTVFGNPGSNELPFLKDFPEDFRYILALQEACVVGIADGYAQASRKPAFINLHSAAGTGNAMGALSNAWNSHSPLIVTAGQQTRAMIGVEALLTNVDAANLPRPLVKWSYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDADPQSHHLFDRHVSSSVRLNDQDLDILVKALNSASNPAIVLGPDVDAANANADCVMLAERLKAPVWVAPSAPRCPFPTRHPCFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYHQYDPGQYLKPGTRLISVTCDPLEAARAPMGDAIVADIGAMASALANLVEESSRQLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTSTTAQMWQRLNMRNPGSYYFCAAGGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIMNNGTYGVLRWIAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSAKGPVLIEVSTVS 5dgx A 1.73 BS01 ADP A 1 F381 H384 V386 S406 G407 S408 G409 K410 T411 T412 F24 H27 V29 S49 G50 S51 G52 K53 T54 T55 3.6.3.- Q14JW6 KETGSKELAKVDGNVTIKDLSFAFGEHKVLSGVSVDIKAGQTVAFVGKSGSGKTTLTSIISRFYTQHEGEILLDGVDTRELTLENLRSHLSIVSQNVHLFDDTVYNNIAFGEVSEEEVIDALKRANAYEFVQELSDGINTNIGNNGSKLSGGQRQRISIARALLKNAPVLIFDELESLTKSCTTIVIAHRLSTVENADKIVVMDGGRVVESGKHQELLEQGGLYTRLYQSGLQ 5dh9 A 2.55 BS01 GNP A 1 G19 G20 T21 G22 K23 T24 T25 E36 K37 Y39 A41 T42 G68 N122 K123 D125 I126 S150 A151 K152 G11 G12 T13 G14 K15 T16 T17 E28 K29 Y31 A33 T34 G60 N114 K115 D117 I118 S142 A143 K144 P62826 26349033 VQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEDPALAAQYEHDLEVAQTTALPDEDDDL 5dh9 C 2.55 BS01 III D 1 I532 L536 K545 A549 F565 H569 N571 F572 T575 V576 K579 F583 I474 L478 K487 A491 F507 H511 N513 F514 T517 V518 K521 F525 P30822 26349033 SMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFA 5dha A 2.95 BS01 GNP A 1 G20 T21 G22 K23 T24 T25 E36 K37 K38 Y39 T42 G68 N122 K123 D125 I126 S150 A151 K152 G12 T13 G14 K15 T16 T17 E28 K29 K30 Y31 T34 G60 N114 K115 D117 I118 S142 A143 K144 P62826 26349033 VQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVDPALAAQYEHDLEVAQTTALPDEDDDL 5dha C 2.95 BS01 III D 1 V529 I532 L536 K548 H569 F572 T575 K579 F583 E586 V471 I474 L478 K490 H511 F514 T517 K521 F525 E528 P30822 26349033 SMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFA 5dhf A 2.29 BS01 GNP A 1 G19 G20 T21 G22 K23 T24 T25 F35 E36 K37 Y39 T42 G68 N122 K123 D125 I126 A151 K152 G11 G12 T13 G14 K15 T16 T17 F27 E28 K29 Y31 T34 G60 N114 K115 D117 I118 A143 K144 P62826 26349033 VQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVPALAAQYEHDLEVAQTTALPDEDDDL 5dhf C 2.29 BS01 III D 1 I532 L536 A549 M556 H569 T575 V576 K579 E582 F583 E586 V591 I474 L478 A491 M498 H511 T517 V518 K521 E524 F525 E528 V533 P30822 26349033 SMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPEIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFA 5dhf C 2.29 BS02 ZN C 1 M156 S216 Y220 M157 S217 Y221 P30822 26349033 SMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPEIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFA 5dhk A 2.43 BS01 MG A 1 D305 E379 D293 E367 4.2.3.61 Q40577 IVRPVADFSPSLWGDQFLSFSIKNQVAEKYAKEIEALKEQTRNMLLATGMKLADTLNLIDTIERLGISYHFEKEIDDILDQIYNQNSNCNDLCTSALQFRLLRQHGFNISPEIFSKFQDENGKFKESLASDVLGLLNLYEASHVRTHADDILEDALAFSTIHLESAAPHLKSPLREQVTHALEQCLHKGVPRVETRFFISSIYDKEQSKNNVLLRFAKLDFNLLQMLHKQELAQVSRWWKDLDFVTTLPYARDRVVECYFEALGVYFEPQYSQARVMLVKTISMISIVDDTFDAYGTVKELEAYTDAIQRWDINEIDRLPDYMKISYKAILDLYKDYEKELSSAGRSHIVCHAIERMKEVVRNYNVESTWFIEGYTPPVSEYLSNALATTTYYYLATTSYLGMKSATEQDFEWLSKNPKILEASVIICRVIDDTATYEVEKSRGQIATGIECCMRDYGISTKEAMAKFQNMAETAWKDINEGLLRPTPVSTEFLTPILNLARIVEVTYIHNLDGYTHPEKVLKPHIINLLVDSIKI 5dhk A 2.43 BS03 FAR A 1 E273 I294 S298 T402 L407 C440 D444 I515 V516 Y520 Y527 E261 I282 S286 T390 L395 C428 D432 I503 V504 Y508 Y515 4.2.3.61 Q40577 IVRPVADFSPSLWGDQFLSFSIKNQVAEKYAKEIEALKEQTRNMLLATGMKLADTLNLIDTIERLGISYHFEKEIDDILDQIYNQNSNCNDLCTSALQFRLLRQHGFNISPEIFSKFQDENGKFKESLASDVLGLLNLYEASHVRTHADDILEDALAFSTIHLESAAPHLKSPLREQVTHALEQCLHKGVPRVETRFFISSIYDKEQSKNNVLLRFAKLDFNLLQMLHKQELAQVSRWWKDLDFVTTLPYARDRVVECYFEALGVYFEPQYSQARVMLVKTISMISIVDDTFDAYGTVKELEAYTDAIQRWDINEIDRLPDYMKISYKAILDLYKDYEKELSSAGRSHIVCHAIERMKEVVRNYNVESTWFIEGYTPPVSEYLSNALATTTYYYLATTSYLGMKSATEQDFEWLSKNPKILEASVIICRVIDDTATYEVEKSRGQIATGIECCMRDYGISTKEAMAKFQNMAETAWKDINEGLLRPTPVSTEFLTPILNLARIVEVTYIHNLDGYTHPEKVLKPHIINLLVDSIKI 5di9 C 2.28 BS01 III D 1 K525 V529 L536 C539 K548 A549 I555 M556 H569 N571 T575 K579 F583 V591 K468 V472 L479 C482 K491 A492 I498 M499 H512 N514 T518 K522 F526 V534 P30822 26349033 SMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPETIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFA 5dif C 2.09 BS01 III D 1 K525 I532 L536 E540 K545 A549 H569 N571 F572 T575 V576 K579 F583 E586 V591 K469 I476 L480 E484 K489 A493 H513 N515 F516 T519 V520 K523 F527 E530 V535 P30822 26349033 GSMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENMVRPETIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFAE 5dlc A 2.65 BS01 PO4 A 1 H204 G205 G226 H227 H192 G193 G214 H215 2.6.99.2 Q02HS5 TRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVRVLKEVLQTRMNFEMGVTEEMLAFAEEIRPAHSCLVPERREELTTEGGLDVAGQEQRIRDAVRRLAAVGSEVSLFIDPDPRQIEASARVGAPAIELHTGRYADAEDPEEQARELQRVREGVALGRSLGLIVNAGHGLHYHNVEPVAAIDGINELNIGHAIVAHALFVGFRQAVAEMKALMLAAAT 5dll A 2.51 BS01 ZN A 1 H306 H310 E329 H296 H300 E319 3.4.11.2 Q5NE65 KIKYLKDYKPSNYLIDETHLIFELDESKTRVTANLYIVANRENRENNTLVLDGVELKLLSIKLNNKHLSPAEFAVNENQLIINNVPEKFVLQTVVEINPSANTSLEGLYKSGDVFSTQCEATGFRKITYYLDRPDVMAAFTVKIIADKKKYPIILSNGDKIDSGDISDNQHFAVWKDPFKKPCYLFALVAGDLASIKDTYITKSQRKVSLEIYAFKQDIDKCHYAMQAVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAMENKGLNIFNTKYIMASNKTATDKDFELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFRDQEFTSDLNSRDVKRIDDVRIIRSAQFAEDASPMSHPIRPESYIEMNNFYTVTVYNKGAEIIRMIHTLLGEEGFQKGMKLYFERHDGQAVTCDDFVNAMADANNRDFSLFKRWYAQSGTPNIKVSENYDASSQTYSLTLEQTTLPTADQKEKQALHIPVKMGLINPEGKNIAEQVIELKEQKQTYTFENIAAKPVASLFRDFSAPVKVEHKRSEKDLLHIVKYDNNAFNRWDSLQQIATNIILNNADLNDEFLNAFKSILHDKDLDKALISNALLIPIESTIAEAMRVIMVDDIVLSRKNVVNQLADKLKDDWLAVYQQCNDNKPYSLSAEQIAKRKLKGVCLSYLMNASDQKVGTDLAQQLFDNADNMTDQQTAFTELLKSNDKQVRDNAINEFYNRWRHEDLVVNKWLLSQAQISHESALDIVKGLVNHPAYNPKNPNKVYSLIGGFGANFLQYHCKDGLGYAFMADTVLALDKFNHQVAARMARNLMSWKRYDSDRQAMMKNALEKIKASNPSKNVFEIVSKSLES 5dm3 A 2.60 BS01 ADP A 1 I139 A141 E143 E201 R217 C218 H264 S266 R348 I103 A105 E107 E141 R154 C155 H201 S203 R280 6.3.1.2 Q1QZR8 TLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCIMKPDLATLRCVPWLEGTAMVLCDLLHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDTTKEEHVLRPLRNHLHAAGIPVEGTKGEGQEELNIRCAKALDTADYHTIAKHATKEIAWQQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAGLIPQNLRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFE 5dm3 A 2.60 BS02 ADP C 1 T51 H52 T48 H49 6.3.1.2 Q1QZR8 TLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCIMKPDLATLRCVPWLEGTAMVLCDLLHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDTTKEEHVLRPLRNHLHAAGIPVEGTKGEGQEELNIRCAKALDTADYHTIAKHATKEIAWQQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAGLIPQNLRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFE 5dm3 B 2.60 BS01 ADP B 1 I139 A141 E143 E201 I216 R217 C218 H264 S266 R348 I107 A109 E111 E146 I159 R160 C161 H207 S209 R291 6.3.1.2 Q1QZR8 NTLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCYIMKPDLATLRCVPWLEGTAMVLCDLLDHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDETTKEEHVLRPLRNHLHAAGIPVEGTKGEAGQEELNIRCAKALDTADYHTIAKHATKEIAWQQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQKGTFAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAGLIPQNLRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFE 5dm3 C 2.60 BS01 ADP C 1 I139 A141 E201 I216 R217 C218 H264 S266 R348 I111 A113 E157 I172 R173 C174 H220 S222 R301 6.3.1.2 Q1QZR8 ALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLLYIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDEIRKGRFRTTKEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAWQQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQFAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPASGLIPQNLRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFE 5dm3 D 2.60 BS01 ADP A 1 K36 T51 H52 K33 T48 H49 6.3.1.2 Q1QZR8 TLALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYLYIMKPDLATLRCVPWLEGTAMVLCDLLDHRTHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDTTKEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAWQQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAELIPQNLRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGFE 5dm3 F 2.60 BS01 ADP F 1 I139 A141 E143 E201 I216 C218 H264 S266 W268 A346 R348 I106 A108 E110 E144 I159 C161 H207 S209 W211 A286 R288 6.3.1.2 Q1QZR8 LALDDLKTRVESGEIDTVLVCIVDMQGRLMGKRLHARHFVDHGWEETHCCNYYIMKPDLATLRCVPWLEGTAMVLCDLLHAEVPHAPRAILKRQLARLEAMGLEAIMATELEFFLFEKSLDTTKEEHVLRPLRNHLHAAGIPVEGTKGEAGAGQEELNIRCAKALDTADYHTIAKHATKEIAWQQGRAVTFLSKWHHAHAGSSSHIHQSLWKQGLPAFHDERDALGMSALMKHYLAGLLKYAPDYTYFLAPYLNSYKRFQKAPTRTVWSVDNRTAGFRLCAEGTRAVRIECRIGGSDLNPYLAMAGQLAAGIKGIEECLALPPPAELIPQNLRDAMEALRGSTMLREAMGEDVVDHYVRAAEVELEDFQRVVSDYEVARGF