2my3 A BS01 III B 1 N19 E21 L22 T23 E24 G25 D26 L28 T29 V30 R44 D45 E46 N47 K76 I77 G78 K97 Y98 A101 V102 E105 N19 E21 L22 T23 E24 G25 D26 L28 T29 V30 R44 D45 E46 N47 K76 I77 G78 K97 Y98 A101 V102 E105 P40565 26212312 GAMGNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQKYYEAVKEELDRDIVSKNNAEK 3jak E 3.50 BS01 GTP E 1 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 T179 E183 N206 Y224 N228 Q11 A12 Q15 D89 A90 N92 S131 G134 G135 T136 G137 I162 T170 E174 N197 Y215 N219 Q2XVP4 26234155 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVE 3jak F 3.50 BS01 GSP F 1 G10 Q11 C12 Q15 E71 N101 S140 G143 G144 T145 G146 D179 N206 Y224 N228 G10 Q11 C12 Q15 E69 N99 S138 G141 G142 T143 G144 D177 N204 Y222 N226 P02554 26234155 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAT 3jal F 3.50 BS01 G2P F 1 G10 Q11 C12 Q15 S140 G143 T145 G146 D179 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 T143 G144 D177 N204 Y222 N226 26234155 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAT 3jam b 3.46 BS01 ZN b 1 C37 G39 C40 C59 C36 G38 C39 C58 Q6CNL2 26212456 VLVQDLLHPTAASEARKHKLKTLVQSPRSHFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK 3jam f 3.46 BS01 MG f 1 Y85 T87 Y4 T6 P69061 26212456 KKVYTTPKKIRHKHKKVKLAVLNYYKVDDEGKVAKLRKECPNCGPGIFLANHGDRFYCGKCHSTFATQK 3jam f 3.46 BS02 ZN f 1 C121 I128 C139 C142 C40 I47 C58 C61 P69061 26212456 KKVYTTPKKIRHKHKKVKLAVLNYYKVDDEGKVAKLRKECPNCGPGIFLANHGDRFYCGKCHSTFATQK 3jas E 3.50 BS02 MG E 1 E71 D98 E62 D89 Q2XVP4 26234155 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 3jas J 3.50 BS02 MG J 1 Q11 E71 D98 Q11 E62 D89 Q2XVP4 26234155 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 3jat E 3.50 BS01 GTP E 1 G10 Q11 A12 Q15 A99 A100 N101 S140 G143 G144 T145 G146 I171 T179 N206 Y224 N228 G10 Q11 A12 Q15 A90 A91 N92 S131 G134 G135 T136 G137 I162 T170 N197 Y215 N219 26234155 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 3jat F 3.50 BS01 G2P F 1 G10 Q11 C12 Q15 A99 N101 G143 G144 T145 G146 D179 N206 Y224 N228 G10 Q11 C12 Q15 A97 N99 G141 G142 T143 G144 D177 N204 Y222 N226 P02554 26234155 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 3jat G 3.50 BS01 G2P G 1 G10 Q11 C12 Q15 A99 N101 G144 T145 G146 N206 Y224 N228 G10 Q11 C12 Q15 A97 N99 G142 T143 G144 N204 Y222 N226 P02554 26234155 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQ 3jat C 3.50 BS01 GTP C 1 G10 Q11 A12 Q15 A99 N101 S140 G143 G144 T145 G146 T179 N206 Y224 N228 G10 Q11 A12 Q15 A90 N92 S131 G134 G135 T136 G137 T170 N197 Y215 N219 Q2XVP4 26234155 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGV 3jay A 3.00 BS01 SAM A 1 N526 S528 M532 G562 E566 D589 R590 R599 V600 D616 I617 N618 E631 N526 S528 M532 G562 E566 D589 R590 R599 V600 D616 I617 N618 E631 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jay A 3.00 BS02 SAM A 2 Y842 I861 G862 G863 R864 A867 D868 I881 D882 P883 F904 F906 I922 A923 N927 E928 P929 Y992 Y842 I861 G862 G863 R864 A867 D868 I881 D882 P883 F904 F906 I922 A923 N927 E928 P929 Y992 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jay A 3.00 BS03 ATP A 1 R271 S301 D302 Y305 Y316 Y320 R271 S301 D302 Y305 Y316 Y320 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jay A 3.00 BS04 GTP A 1 R12 Y59 N61 M116 P165 T167 Y179 H208 H212 H217 F219 K234 R255 R12 Y59 N61 M116 P165 T167 Y179 H208 H212 H217 F219 K234 R255 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb0 A 2.90 BS01 GTP A 1 R12 Y59 N61 M116 P165 Y179 H208 F219 K234 E237 R255 R12 Y59 N61 M116 P165 Y179 H208 F219 K234 E237 R255 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb1 A 3.10 BS01 SAM A 1 Y842 I861 G862 R864 A867 I881 D882 P883 A884 F904 F906 I922 A923 N927 E928 P929 Y842 I861 G862 R864 A867 I881 D882 P883 A884 F904 F906 I922 A923 N927 E928 P929 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb2 A 3.10 BS01 SAM A 1 N526 S528 M532 G562 E564 E566 D589 R590 R599 V600 D616 I617 N618 Y620 E631 N526 S528 M532 G562 E564 E566 D589 R590 R599 V600 D616 I617 N618 Y620 E631 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb2 A 3.10 BS02 SAM A 2 K838 Y842 I861 G862 G863 R864 A867 D868 I881 D882 P883 F904 F906 I922 A923 V924 N927 E928 P929 K838 Y842 I861 G862 G863 R864 A867 D868 I881 D882 P883 F904 F906 I922 A923 V924 N927 E928 P929 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb2 A 3.10 BS03 GTP A 1 Y268 R271 D302 Y305 Y316 Y320 Y268 R271 D302 Y305 Y316 Y320 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb2 A 3.10 BS04 GTP A 2 R12 Y59 N61 M116 I164 P165 Y179 H208 H212 H217 F219 R255 R12 Y59 N61 M116 I164 P165 Y179 H208 H212 H217 F219 R255 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb3 A 3.10 BS01 SAM A 1 S528 M532 G562 E564 E566 D589 R590 V598 R599 V600 D616 I617 N618 S528 M532 G562 E564 E566 D589 R590 V598 R599 V600 D616 I617 N618 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb3 A 3.10 BS03 ATP A 1 Y268 R271 S301 D302 Y305 Y316 Y320 Y268 R271 S301 D302 Y305 Y316 Y320 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3jb3 A 3.10 BS04 GTP A 1 R12 Y59 N61 M116 P165 I166 Y179 H208 H212 W213 H217 F219 K234 R255 R12 Y59 N61 M116 P165 I166 Y179 H208 H212 W213 H217 F219 K234 R255 Q914N6 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVR 3wwh A 1.65 BS01 PLP A 1 R86 K188 E221 G224 F225 N226 L243 G245 I246 T247 T282 T283 R85 K187 E220 G223 F224 N225 L242 G244 I245 T246 T281 T282 2.6.1.18 F7J696 AFSADTSEIVYTHDTGLDYITYSDYELDPANPLAGGAAWIEGAFVPPSEARISIFDQGYLHSDVTYTVFHVWNGNAFRLDDHIERLFSNAESMRIIPPLTQDEVKEIALELVAKTELREAFVSVSITRGYSSTPGERDITKHRPQVYMYAVPYQWIVPFDRIRDGVHAMVAQSVRRTPRSSIDPQVKNFQWGDLIRAVQETHDRGFEAPLLLDGDGLLAEGSGFNVVVIKDGVVRSPGRAALPGITRKTVLEIAESLGHEAILADITLAELLDADEVLGCTTAGGVWPFVSVDGNPISDGVPGPITQSIIRRYWELNVESSSLLTPVQY 3wwj B 2.20 BS01 PLP B 1 R86 K188 W192 E221 G222 G224 F225 N226 L243 G245 I246 T247 T283 R79 K181 W185 E214 G215 G217 F218 N219 L236 G238 I239 T240 T276 2.1.6.18 F7J696 PEIVYTHDTGLDYITYSDYELDPANPLAGGAAWIEGAFVPPSEARISIFDQGFYTSDATYTTFHVWNGNAFRLGDHIERLFSNAESIRLIPPLTQDEVKEIALELVAKTELREAMVTVTITRGYSSTPFERDITKHRPQVYMSACPYQWIVPFDRIRDGVHLMVAQSVRRTPRSSIDPQVKNFQWGDLIRAIQETHDRGFELPLLLDCDNLLAEGPGFNVVVIKDGVVRSPGRAALPGITRKTVLEIAESLGHEAILADITPAELYDADEVLGCSTGGGVWPFVSVDGNSISDGVPGPVTQSIIRRYWELNVEPSSLLTPVQY 3wwj E 2.20 BS01 PLP E 1 R86 K188 W192 E221 G224 F225 L243 G245 I246 T247 T283 R77 K179 W183 E212 G215 F216 L234 G236 I237 T238 T274 2.1.6.18 F7J696 IVYTHDTGLDYITYSDYELDPANPLAGGAAWIEGAFVPPSEARISIFDQGFYTSDATYTTFHVWNGNAFRLGDHIERLFSNAESIRLIPPLTQDEVKEIALELVAKTELREAMVTVTITRGYSSTPFERDITKHRPQVYMSACPYQWIVPFDRIRDGVHLMVAQSVRRTPRSSIDPQVKNFQWGDLIRAIQETHDRGFELPLLLDCDNLLAEGPGFNVVVIKDGVVRSPGRAALPGITRKTVLEIAESLGHEAILADITPAELYDADEVLGCSTGGGVWPFVSVDGNSISDGVPGPVTQSIIRRYWELNVEPSSLLTPVQY 4mvi A 1.70 BS01 III B 1 V36 W49 K50 Y52 T54 S68 V69 G70 H77 K79 R81 L94 T104 F123 V125 Q127 N134 T136 Y138 P169 V31 W44 K45 Y47 T49 S63 V64 G65 H72 K74 R76 L89 T99 F118 V120 Q122 N129 T131 Y133 P164 P80188 DLIPAPPLSKVPLQQNFQDNQFHGKWYVVGVAGNKSLREDKDPWKMYATIYELKEDKSYNVTSVGFGTKKCHYKIRTFVPGSQPGEFTLGRIKSRPGRTSALVRVVSTNYNQHAMVFFKVVQQNRESFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4mvk A 1.50 BS01 III B 1 V36 W49 K50 Y52 T54 S68 V69 G70 G72 H77 K79 R81 F83 F123 V125 Q127 N134 T136 Y138 P169 V30 W43 K44 Y46 T48 S62 V63 G64 G66 H71 K73 R75 F77 F117 V119 Q121 N128 T130 Y132 P163 P80188 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGVAGNKSLREDKDPWKMYATIYELKEDKSYNVTSVGFGTKKCHYKIRTFVPGSQPGEFTLGRIKSRPGRTSALVRVVSTNYNQHAMVFFKVVQQNRESFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4mvl A 2.30 BS01 III E 1 A36 R43 L49 K50 Y52 T54 S68 V69 G70 F71 D72 L77 K79 R81 L94 W106 F123 N134 Y138 P169 A32 R39 L45 K46 Y48 T50 S64 V65 G66 F67 D68 L73 K75 R77 L90 W102 F119 N130 Y134 P165 P80188 SDLIPAPPLSKVPLQQNFQDNQFHGKWYVVGAAGNVLLREDKDPLKMYATIYELKEDKSYNVTSVGFDDKKCLYKIRTFVPGSQPGEFTLGRIKSEPGGTSWLVRVVSTNYNQHAMVFFKEVAQNRETFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4mvl B 2.30 BS01 III F 1 L49 K50 Y52 T54 S68 G70 F71 L77 K79 R81 F83 L94 W106 F123 N134 T136 Y138 P169 L44 K45 Y47 T49 S63 G65 F66 L72 K74 R76 F78 L89 W101 F118 N129 T131 Y133 P164 P80188 DLIPAPPLSKVPLQQNFQDNQFHGKWYVVGAAGNVLLREDKDPLKMYATIYELKEDKSYNVTSVGFDDKKCLYKIRTFVPGSQPGEFTLGRIKSEPGGTSWLVRVVSTNYNQHAMVFFKEVAQNRETFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4mvl C 2.30 BS01 III G 1 K50 Y52 T54 S68 V69 D72 L77 K79 R81 W106 F123 N134 T136 Y138 P169 K46 Y48 T50 S64 V65 D68 L73 K75 R77 W102 F119 N130 T132 Y134 P165 P80188 SDLIPAPPLSKVPLQQNFQDNQFHGKWYVVGAAGNVLLREDKDPLKMYATIYELKEDKSYNVTSVGFDDKKCLYKIRTFVPGSQPGEFTLGRIKSEPGGTSWLVRVVSTNYNQHAMVFFKEVAQNRETFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 4mvl D 2.30 BS01 III H 1 A36 L49 K50 Y52 T54 S68 V69 D72 L77 K79 R81 F83 L94 W106 F123 N134 Y138 P169 A30 L43 K44 Y46 T48 S62 V63 D66 L71 K73 R75 F77 L88 W100 F117 N128 Y132 P163 P80188 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGAAGNVLLREDKDPLKMYATIYELKEDKSYNVTSVGFDDKKCLYKIRTFVPGSQPGEFTLGRIKSEPGGTSWLVRVVSTNYNQHAMVFFKEVAQNRETFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4n1m A 1.15 BS02 PRO A 1 R55 F60 M61 Q63 F113 L122 H126 R58 F63 M64 Q66 F116 L125 H129 5.2.1.8 P62937 SHMMVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1n A 1.50 BS01 UNU A 1 F60 M61 Q63 A101 N102 F113 L122 H126 F60 M61 Q63 A101 N102 F113 L122 H126 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1o A 1.75 BS01 LSA A 1 G45 F46 F67 K76 G45 F46 F67 K76 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1o A 1.75 BS02 LSA A 2 F60 M61 Q63 A101 N102 F113 H126 F60 M61 Q63 A101 N102 F113 H126 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1o A 1.75 BS03 LSA A 3 P95 V132 K133 E134 G135 M136 P95 V132 K133 E134 G135 M136 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1o A 1.75 BS04 LSA A 4 P30 E34 Y79 P30 E34 Y79 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1o A 1.75 BS05 LSA A 5 P30 K31 P30 K31 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1p A 1.90 BS01 WM1 A 1 F60 A101 N102 F113 L122 H126 F60 A101 N102 F113 L122 H126 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1p A 1.90 BS02 WM1 A 2 G72 A101 N102 Q111 G72 A101 N102 Q111 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1p A 1.90 BS03 WM1 A 3 E120 W121 E120 W121 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4n1s A 1.47 BS01 WM4 A 1 F60 A101 N102 F113 H126 F60 A101 N102 F113 H126 5.2.1.8 P62937 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4p3w A 2.00 BS01 III G 1 M2207 G2208 T2263 R2264 G2267 A2268 G2269 G2270 L2271 A2272 I2273 A2274 V2275 E2276 G2277 P2278 K2280 A2281 I2283 F2285 E2306 M50 G51 T106 R107 G110 A111 G112 G113 L114 A115 I116 A117 V118 E119 G120 P121 K123 A124 I126 F128 E149 P21333 SHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPS 4p3w E 2.00 BS01 III K 1 M2207 G2208 T2263 R2264 G2267 A2268 G2269 G2270 L2271 A2272 I2273 A2274 V2275 E2276 G2277 P2278 S2279 K2280 A2281 I2283 F2285 E2301 E2306 F2311 M51 G52 T107 R108 G111 A112 G113 G114 L115 A116 I117 A118 V119 E120 G121 P122 S123 K124 A125 I127 F129 E145 E150 F155 P21333 GSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASP 4p3w F 2.00 BS01 III L 1 M2207 G2208 A2268 G2269 G2270 L2271 A2272 I2273 A2274 V2275 E2276 G2277 P2278 K2280 A2281 I2283 F2285 M36 G37 A97 G98 G99 L100 A101 I102 A103 V104 E105 G106 P107 K109 A110 I112 F114 P21333 HCLSLKIMTAQVTSPSGKTHEAEIHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASP 4qe6 A 1.65 BS01 III B 1 V299 K303 H313 E314 Q316 I317 K321 P463 L464 E467 V58 K62 H72 E73 Q75 I76 K80 P219 L220 E223 Q96RI1 HMELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ 4qe6 A 1.65 BS02 JN3 A 1 M265 M290 A291 H294 M328 R331 S332 I335 Y361 Y369 H447 M24 M49 A50 H53 M87 R90 S91 I94 Y117 Y125 H203 Q96RI1 HMELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ 4qe8 A 2.62 BS01 III C 1 V299 K303 H313 Q316 I317 K321 L464 E467 I468 V57 K61 H71 Q74 I75 K79 L216 E219 I220 Q96RI1 MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRKFTPLLCEIWDVQ 4qe8 A 2.62 BS02 31D A 1 F284 L287 T288 M290 A291 H294 M328 R331 I357 M365 M450 S453 R455 F461 F42 L45 T46 M48 A49 H52 M86 R89 I113 M121 M206 S209 R211 F213 Q96RI1 MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRKFTPLLCEIWDVQ 4qe8 B 2.62 BS01 III D 1 V299 K303 H313 Q316 I317 K321 L464 V57 K61 H71 Q74 I75 K79 L215 Q96RI1 MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWKFTPLLCEIWDVQ 4qe8 B 2.62 BS02 31D B 1 F284 M290 A291 H294 M328 R331 I357 M365 M450 S453 W469 F42 M48 A49 H52 M86 R89 I113 M121 M206 S209 W220 Q96RI1 MELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWKFTPLLCEIWDVQ 4qoj A 1.85 BS01 FMN A 1 H11 S16 F17 N18 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 H10 S15 F16 N17 P101 L102 Y103 W104 F105 T146 T147 G148 G149 Y154 E192 1.10.99.2 P16083 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 4qoj A 1.85 BS02 STL A 1 G68 L120 F126 G174 F178 G67 L119 F125 G173 F177 1.10.99.2 P16083 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 4qoj B 1.85 BS04 STL B 1 G68 L120 F126 Y132 G174 F178 G67 L119 F125 Y131 G173 F177 1.10.99.2 P16083 GKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 4r1p A 2.30 BS01 MN A 1 E307 E332 H349 H448 E305 E330 H347 H446 5.3.1.4 Q5KYP7 LSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRG 4r1p E 2.30 BS01 MN E 1 E307 E332 H349 H447 H448 E306 E331 H348 H446 H447 5.3.1.4 Q5KYP7 MLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRG 4r1q A 2.25 BS01 SST A 1 M186 E307 E332 M350 I371 H447 H448 M185 E306 E331 M349 I370 H446 H447 5.3.1.4 Q5KYP7 MLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRG 4r1q A 2.25 BS02 SST A 2 Q17 L19 Y20 F84 Q126 H129 Q16 L18 Y19 F83 Q125 H128 5.3.1.4 Q5KYP7 MLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRG 4r1q B 2.25 BS03 SST C 1 Y20 F84 Q126 H129 Y18 F82 Q124 H127 5.3.1.4 Q5KYP7 LSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRGR 4r1q D 2.25 BS01 SST A 3 M186 E307 E332 H447 H448 M186 E307 E332 H447 H448 5.3.1.4 Q5KYP7 MMLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRG 4r1q E 2.25 BS02 SST E 1 M186 E307 E332 H349 M350 I371 H447 H448 M185 E306 E331 H348 M349 I370 H446 H447 5.3.1.4 Q5KYP7 MLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRGR 4r1q F 2.25 BS02 SST C 3 M186 E307 E332 M350 H447 H448 M185 E306 E331 M349 H446 H447 5.3.1.4 Q5KYP7 MLSLRPYEFWFVTGSQHLYGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKSVVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLHLHTQFNRDIPWDSIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLAKWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVPAGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNELILGAHMLEVCPTIAATRPRVEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRG 4r2n A 1.98 BS01 PLP A 1 G84 S85 V86 F110 C153 N157 D184 A186 Y187 T214 S216 K217 R225 G84 S85 V86 F110 C153 N157 D184 A186 Y187 T214 S216 K217 R225 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n A 1.98 BS02 PHE A 1 Y15 V86 F110 E111 L112 N157 K217 R330 Y15 V86 F110 E111 L112 N157 K217 R330 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n A 1.98 BS03 PHE C 1 P245 F246 P245 F246 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n B 1.98 BS02 PHE B 1 Y15 V86 F110 E111 L112 N157 R330 Y15 V86 F110 E111 L112 N157 R330 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n B 1.98 BS03 PHE D 1 N57 F246 N57 F246 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n C 1.98 BS01 PHE A 1 Y54 P245 F246 Y54 P245 F246 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n C 1.98 BS03 PHE C 1 V86 F110 E111 L112 R322 V86 F110 E111 L112 R322 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r2n D 1.98 BS03 PHE D 1 Y15 E111 R322 Y15 E111 R322 2.6.1.- I6Y4H4 VTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ 4r3p A 2.90 BS01 III B 1 D837 R841 G874 K875 V876 P877 I878 K879 R889 A920 D142 R146 G179 K180 V181 P182 I183 K184 R194 A225 2.7.10.1 P00533 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPDEDMDDVVDADEYLI 4r3r A 3.25 BS01 III B 1 D837 R841 N842 D855 K875 V876 P877 I878 K879 I886 A920 D141 R145 N146 D159 K179 V180 P181 I182 K183 I190 A224 2.7.10.1 P00533 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELRATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPDEDMDDVVDADEYLI 4r73 A 1.60 BS01 G6P A 1 S9 R34 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 Q269 S11 R36 S39 G61 Y105 S150 G151 T152 G187 I188 H207 D208 E231 Q271 A3N294 GSKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLAK 4r73 B 1.60 BS01 G6P B 1 S9 T11 R34 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 Q269 S10 T12 R35 S38 G60 Y104 S149 G150 T151 G186 I187 H206 D207 E230 Q270 A3N294 SKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLA 4r74 A 1.93 BS01 F6P A 1 S9 T11 S37 G59 Y103 S148 G149 T150 G185 I186 F203 H205 D206 E229 Q269 S10 T12 S38 G60 Y104 S149 G150 T151 G186 I187 F204 H206 D207 E230 Q270 A3N294 SKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLA 4r74 B 1.93 BS02 MG B 1 N241 D243 N244 N243 D245 N246 A3N294 GSKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLA 4r75 A 1.28 BS01 S7P A 1 S9 T11 G36 S37 G38 G59 T60 Y103 S148 G149 T150 G185 I186 F203 H205 D206 E229 Q269 S9 T11 G36 S37 G38 G59 T60 Y103 S148 G149 T150 G185 I186 F203 H205 D206 E229 Q269 A3N294 KGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNNPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSSAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGTAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVGIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVDFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGASDERKRLINKWVDEIKLA 4r78 A 1.45 BS01 AMP A 1 N32 I43 E89 Y90 I91 T96 E180 N181 I183 I193 D194 N35 I46 E92 Y93 I94 T99 E183 N184 I186 I196 D197 2.7.1.32 Q93MI3 25781969 GSHMEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSIKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRAVKGLASYG 4r7b A 2.01 BS01 CHT A 1 M28 D176 E213 W251 W254 Y268 M31 D179 E216 W254 W257 Y271 2.7.1.32 Q93MI3 25781969 GSHMEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSIKTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEKRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRAVKGLASYG 4r7h A 2.80 BS01 P31 A 1 W550 L588 A614 E633 I636 M637 V647 E664 C666 G669 L785 G795 D796 F797 W7 L40 A66 E85 I88 M89 V99 E116 C118 G121 L178 G188 D189 F190 2.7.10.1 P07333 26222558 PKYQVRWKIIESYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCTYGDLLNFLRRKAEAMLGPSLGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDSVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQITSFLQEQAQ 4r7i A 2.75 BS01 STI A 1 V596 A614 K616 E633 M637 V661 T663 C666 C774 I775 H776 R777 L785 G795 D796 F797 V30 A48 K50 E67 M71 V95 T97 C100 C150 I151 H152 R153 L161 G171 D172 F173 2.7.10.1 P07333 26222558 TQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCTYGDLLNFLRRKAEAMLGPSLSGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDSVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQITSFLQEQA 4rgz A 2.60 BS01 ZN A 1 D229 D240 E347 D226 D237 E344 C6A2N7 GSMDYKRRIHKFQAHFGKKGFEGALVAPGSNFYYLTGFNPLGTLERLFVLILPSEGLLTAIAPRLYEKELEEFNGEVVLWSDSENPYKIFATKIKETFKEGEKLLIDDTMPVGVFLKAKDIFDKYSLHPISPVISELREIKDKDEIKAHKKAAEIVDKVFYRFIEGKLEGKSERELANRIEYMIKNEFGADDVSFEPIVASGPNGANPHHRPSHRKIRKGDVVIFDYGAKYLGYCSDVTRTVVVGPPSEEVKKVYEIVKEAQETAVQKVAEGIPAEVVDATARGIISKYGYGEYFIHRTGHGLGIDVHEEPYISPGNKKILKDGMVFTIEPGIYLQGKFGVRIEDDVALVDKKGIRLTNADRELITL 4rgz e 2.60 BS01 ZN e 1 D229 D240 T242 E347 D226 D237 T239 E344 C6A2N7 GSMDYKRRIHKFQAHFGKKGFEGALVAPGSNFYYLTGFNPLGTLERLFVLILPSEGLLTAIAPRLYEKELEEFNGEVVLWSDSENPYKIFATKIKETFKEGEKLLIDDTMPVGVFLKAKDIFDKYSLHPISPVISELREIKDKDEIKAHKKAAEIVDKVFYRFIEGKLEGKSERELANRIEYMIKNEFGADDVSFEPIVASGPNGANPHHRPSHRKIRKGDVVIFDYGAKYLGYCSDVTRTVVVGPPSEEVKKVYEIVKEAQETAVQKVAEGIPAEVVDATARGIISKYGYGEYFIHRTGHGLGIDVHEEPYISPGNKKILKDGMVFTIEPGIYLQGKFGVRIEDDVALVDKKGIRLTNADRELITL 4rgz e 2.60 BS02 ZN e 2 H304 E333 E347 H301 E330 E344 C6A2N7 GSMDYKRRIHKFQAHFGKKGFEGALVAPGSNFYYLTGFNPLGTLERLFVLILPSEGLLTAIAPRLYEKELEEFNGEVVLWSDSENPYKIFATKIKETFKEGEKLLIDDTMPVGVFLKAKDIFDKYSLHPISPVISELREIKDKDEIKAHKKAAEIVDKVFYRFIEGKLEGKSERELANRIEYMIKNEFGADDVSFEPIVASGPNGANPHHRPSHRKIRKGDVVIFDYGAKYLGYCSDVTRTVVVGPPSEEVKKVYEIVKEAQETAVQKVAEGIPAEVVDATARGIISKYGYGEYFIHRTGHGLGIDVHEEPYISPGNKKILKDGMVFTIEPGIYLQGKFGVRIEDDVALVDKKGIRLTNADRELITL 4ri2 A 2.35 BS01 CLA B 1 E173 T174 E142 T143 Q02060 AKAPKKVEKPKLKVEDGLFGTSGGIGFTKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGRFVDEPTFGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGTGKFITDD 4ri2 B 2.35 BS01 CLA B 1 Y75 L82 F83 L86 Y59 L66 F67 L70 Q02060 LKVEDGLFGTSGGIGFTKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGRFVDEPFGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGTGKFIT 4ri3 A 2.70 BS01 DCW A 1 G151 F154 S155 G158 Q169 E173 G119 F122 S123 G126 Q137 E141 Q02060 AKAPKKVEKPKLKVEDGLFGTSGGIGFTKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGRFVDEPFGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGTGKFIT 4ri3 B 2.70 BS01 DCW B 1 G158 Q169 L170 E173 G114 Q125 L126 E129 Q02060 LKVEDGLFGTSGGIGFTKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGRFVDEPGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGTGKFIT 4ris H 2.30 BS01 III P 1 W33 Y52 D54 D56 L95 Y99 Y100 Y100A D100B G100E Y100G W33 Y52 D55 D57 L99 Y103 Y104 Y105 D106 G109 Y111 EVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWIGWVRQMPGKGLEWMGIIYPGDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARLGGRYYYDSSGYYYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS 4ris L 2.30 BS01 III P 1 A29 S30 N31 Y32 E50 D51 S94 W96 A30 S31 N32 Y33 E51 D52 S97 W99 NFMLTQPHSVSESPGKTVTISCTRSSGSIASNYVQWYQQRPGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDSSSWVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT 4rqw A 2.20 BS01 CA A 1 Q53 D94 E124 Q4 D45 E66 Q9FIP9 DTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGEENTAEQEHRKRVIRELNSLISGDEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFN 4rru A 2.10 BS01 CA A 1 S13 D14 G93 S8 D9 G66 Q9FIP9 SSINFLTSDDDASAAAMEAFIEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGEAEQEHRKRVIRELNSLISGDEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNF 4rs9 A 1.95 BS01 III B 1 Q53 W92 G93 D94 Y96 Y97 L125 N126 E142 E143 E148 F151 L152 M155 Q9 W48 G49 D50 Y52 Y53 L71 N72 E75 E76 E81 F84 L85 M88 Q9FIP9 PQFNEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGENTAEQEHRKRVIRELNSLEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNFN 4rwm A 1.80 BS01 EDO A 1 W211 D262 M323 W174 D225 M286 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS02 EDO A 2 L291 K292 Y303 Q307 N308 L345 D348 L254 K255 Y266 Q270 N271 L308 D311 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS03 EDO A 3 I127 D130 R240 H241 I90 D93 R203 H204 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS04 EDO A 4 G165 N166 N167 K170 G128 N129 N130 K133 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS08 HEM A 3 S135 H136 R142 R143 G144 I145 I147 V154 V158 L178 C179 C182 H183 C234 F243 P245 S98 H99 R105 R106 G107 I108 I110 V117 V121 L141 C142 C145 H146 C197 F206 P208 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS09 HEC A 1 N205 F209 H212 G222 C223 C226 H227 V256 C257 H258 H263 Y320 D322 M323 M325 K439 R525 N168 F172 H175 G185 C186 C189 H190 V219 C220 H221 H226 Y283 D285 M286 M288 K402 R488 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS10 HEM A 4 R143 C179 H183 E186 T187 H190 H198 C234 C237 H238 P245 A248 R249 K290 L291 M306 G309 H311 R106 C142 H146 E149 T150 H153 H161 C197 C200 H201 P208 A211 R212 K253 L254 M269 G272 H274 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS11 HEM A 5 G196 S197 H198 A201 N205 C226 H227 I229 A230 G236 C237 A253 C254 C257 H258 C301 H305 Q314 Y320 G159 S160 H161 A164 N168 C189 H190 I192 A193 G199 C200 A216 C217 C220 H221 C264 H268 Q277 Y283 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4rwm A 1.80 BS12 HEM A 6 H258 E265 W266 Y269 P299 T300 C301 C304 H305 G317 T318 R330 W342 M362 Y438 A442 H443 H221 E228 W229 Y232 P262 T263 C264 C267 H268 G280 T281 R293 W305 M325 Y401 A405 H406 1.7.3.4 Q1PX48 GPTFQDVASQVFGQPVGPDNDGTLYIFGLTAKYTEPEYVDGRGPYKSFLKMLPSIRWYDPEHYWTNGSQTEGVFKNEECVLCHTVQTPTIVNDWKQSSHGSKDIRRGIGIKKDGKPVEDLVGCADCHGNNHQKLEMPTYKLCNDCHPKETAEHRAGGLGSHTHAYTVNVLEFSWHVGKPAEEVTGCAHCHAIAENRCSGCHTRHKFDPAEARKPTACRVCHMGIDHDEWAMYNTSIHGALYEAESARMDWGKKLKKGNYRVPTCAYCHMQNGDHNPQRFGTIYSDMGMFQVDRGAPKHKAKRDSWIKLCQDCHSPRFAADKLKEMDAGVNLSFTKWREAAAVIVGCYLDGVVDPMPEGSAPDWYGHYTFSLLPGGDPRFYATSNLERLGLEMICYLTGNVYKAYAHMSMYNQTYGNGSAFEQDRKLVEIKTEAAKLRRFAAIEKKIGLEHKSADFWKHGEYLDLLPGWKRKPGDVDVEWFKRTDIPHRANADAGVEI 4tn6 A 2.41 BS01 PFO A 1 I23 A36 K38 M80 M82 E83 L84 L85 S88 E90 D91 D132 L135 I148 I22 A35 K37 M79 M81 E82 L83 L84 S87 E89 D90 D131 L134 I147 2.7.11.1,2.7.11.26 P48730 ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 4u2y A 2.48 BS01 RZM A 1 K264 N268 S279 W281 A282 Q324 Y357 D359 R392 D394 N395 E423 D480 K534 Y535 K250 N254 S265 W267 A268 Q310 Y343 D345 R378 D380 N381 E409 D466 K520 Y521 2.4.99.16 Q9L1K2 PTVVGRIPVLDVRPVVQRGRRPAKAVTGESFEVSATVFREGHDAVGANVVLRDPRGRPGPWTPMRELAPGTDRWGATVTAGETGTWSYTVEAWGDPVTTWRHHARIKIPAGLDTDLVLEEGARLYERAAADVPGREDRRELLAAVDALRDESRPAASRLAAALTPQVDAVLARHPLRDLVTSSDPLPLLVERERALYGAWYEFFPRSEGTPHTPHGTFRTAARRLPAIAAMGFDVVYLPPIHPIGTTHRKGRNNTLSATGDDVGSPWAIGSPEGGHDSIHPALGTLDDFDHFVTEAGKLGLEIALDFALQCSPDHPWVHKHPEWFHHRPDGTIAHAENPPKKYQDIYPIAFDADPDGLATETVRILRHWMDHGVRIFRVDNPHTKPVAFWERVIADINGTDPDVIFLAEAFTRPAMMATLAQIGFQQSYTYFTWRNTKQELTEYLTELSGEAASYMRPNFFANTPDILHAYLQHGGRPAFEVRAVLAATLSPTWGIYSGYELCENTPLREGSEEYLDSEKYQLKPRDWTRAAREGTTIAPLVTRLNTIRRENPALRQLRDLHFHPTDKEEVIAYSKRQGSNTVLVVVNLDPRHTQEATVSLDMPQLGLDWHESVPVRDELTGETYHWGRANYVRLEPGRTPAHVCTVLR 4u7w A 1.90 BS01 NDP A 1 G1155 T1157 G1158 F1159 L1160 R1181 R1191 D1216 I1217 N1242 G1243 A1244 V1246 V1281 S1282 T1283 Y1311 K1315 P1337 G1338 V1340 G36 T38 G39 F40 L41 R62 R71 D96 I97 N122 G123 A124 V126 V161 S162 T163 Y191 K195 P217 G218 V220 Q93TX2 26235055 DVTVEMEADAVLDAEIALGKALPPVTGALRTILLTGATGFLGAFLLEELCRRTDARIYCLVRSKTQEGMNRIRKNLESYSLWNEALAPRIVPVRGDIGQPLLGLSEKEFQRLSEEIDAIYHNGALVNFLYPYESMRAANVLGTREILRLATRTRIKPLHYVSTVSVLPLGRKAPIREDEPLEGPSSLVGGYAQSKWVAEKLVREASRRGLPVTILRPGRVTGHSRTGAWNTDDLVCRTLKGCVRMGVAPSVDALLDLTPVDYVSSAIVDLSMRPESIGQTYHLVNPQFVRADEMWNYMRAFGYGLRVLPYDQWLSELGSAASSDSELGDLLMFLQQVDRSVGGPRMVVCDSGDTLKALGGTGTSCPSVDASLISTYLSSLVHRGFLKAPE 4u9y A 2.20 BS01 COA A 1 Q58 F124 Y125 I126 Q131 R132 H133 G134 G136 R137 R158 P159 S160 K162 L163 K165 F166 K169 H170 Q60 F121 Y122 I123 Q128 R129 H130 G131 G133 R134 R155 P156 S157 K159 L160 K162 F163 K166 H167 2.3.1.108 Q5SQI0 GSMEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQ 4uj3 A 3.00 BS01 GNP A 1 S20 G21 V22 G23 K24 S25 N26 F36 N37 L38 S40 S42 T43 G69 N124 K125 D127 L128 S154 A155 L156 S17 G18 V19 G20 K21 S22 N23 F33 N34 L35 S37 S39 T40 G66 N121 K122 D124 L125 S151 A152 L153 P62491 RDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQK 4uj3 G 3.00 BS02 MG G 1 S25 T43 D66 T67 S21 T39 D62 T63 P62491 DDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQK 4uqm A 1.35 BS01 NUC B 1 Q82 D83 Y85 H86 P106 S107 G184 S185 G205 H206 S208 P209 L210 S211 Y214 Q67 D68 Y70 H71 P91 S92 G169 S170 G190 H191 S193 P194 L195 S196 Y199 3.2.2.27 Q9RWH9 RPIIPANLPEDWQEALLPEFSAPYFHELTDFLRQERKEYTIYPPAPDVFNALRYTPLGEVKVLILGQDPYHGPNQAHGLSFSVRPGVRVPPSLRNIYKELTEDIPGFVAPKHGYLRSWAEQGVLLLNAVLTVRAAQANSHQGKGWEHFTDAVIKAVNAKEERVVFILWGSYARKKKKLITGKNHVVIESGHPSPLSEQYFFGTRPFSKTNEALEKAGRGPVEWQLPATV 4uqm A 1.35 BS02 NUC C 1 R103 P209 L210 E212 R88 P194 L195 E197 3.2.2.27 Q9RWH9 RPIIPANLPEDWQEALLPEFSAPYFHELTDFLRQERKEYTIYPPAPDVFNALRYTPLGEVKVLILGQDPYHGPNQAHGLSFSVRPGVRVPPSLRNIYKELTEDIPGFVAPKHGYLRSWAEQGVLLLNAVLTVRAAQANSHQGKGWEHFTDAVIKAVNAKEERVVFILWGSYARKKKKLITGKNHVVIESGHPSPLSEQYFFGTRPFSKTNEALEKAGRGPVEWQLPATV 4uui B 1.79 BS01 PYR B 1 D191 N192 V251 D193 N194 V253 4.1.3.3 P0A6L4 HHHATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVFNIPALSGVKLTLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDNIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQER 4uun A 1.71 BS01 NAI A 1 G11 A13 G14 Q15 I16 D41 I42 A45 R48 V86 A87 S88 I128 G129 N130 D132 L154 L157 P244 G10 A12 G13 Q14 I15 D40 I41 A44 R47 V85 A86 S87 I127 G128 N129 D131 L153 L156 P243 1.1.1.27 O96445 SEAAHVLITGAAGQIGYILSHWIASGELYGDRQVYLHLLDIPPAMNRLTALTMELEDCAFPHLAGFVATTDPKAAFKDIDCAFLVASMPLKPGQVRADLISSNSVIFKNTGEYLSKWAKPSVKVLVIGNPDNTNCEIAMLHAKNLKPENFSSLSMLDQNRAYYEVASKLGVDVKDVHDIIVWGNHGESMVADLTQATFTKEGKTQKVVDVLDHDYVFDTFFKKIGHRAWDILEHRGFTSAASPTKAAIQHMKAWLFGTAPGEVLSMGIPVPEGNPYGIKPGVVFSFPCNVDKEGKIHVVEGFKVNDWLREKLDFTEKDLFHEKEIALNHLAQLEH 4uup A 1.50 BS01 NAI A 1 G11 G14 Q15 I16 L40 E41 I42 A45 V86 G87 S88 F89 P90 R91 L100 N104 I107 Q111 V128 G129 N130 M154 H186 S239 S240 A244 G9 G12 Q13 I14 L38 E39 I40 A43 V84 G85 S86 F87 P88 R89 L98 N102 I105 Q109 V126 G127 N128 M152 H184 S237 S238 A242 1.1.1.37 EPIHVLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAGVVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVKVLVVGNPANTNCLIAMANAPKLGPENFSAMTRLDHNRAIGEIAAKLGVPVDKVHNVVVWGNHSNTQVPDVSHATVDKEGGTKKVSDALPKEYLEGEFVQKIAQRGGAVIEARGASSAASAANAALCHMRDWLFGTKPGDWVSMGIPVPEGNPYGIKPGVIYSFPCTVDKDGKVHIVEGLEINDWVREKMEATEKELIEERETAFKVLAQLEHH 4uup B 1.50 BS01 NAI B 1 G11 A13 G14 Q15 I16 L40 E41 I42 A45 V86 G87 S88 I107 Q111 V128 G129 N130 M154 L157 H186 S239 S240 A244 G9 A11 G12 Q13 I14 L38 E39 I40 A43 V84 G85 S86 I105 Q109 V126 G127 N128 M152 L155 H184 S237 S238 A242 1.1.1.37 EPIHVLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAGVVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVKVLVVGNPANTNCLIAMANAPKLGPENFSAMTRLDHNRAIGEIAAKLGVPVDKVHNVVVWGNHSNTQVPDVSHATVDKEGGTKKVSDALPKEYLEGEFVQKIAQRGGAVIEARGASSAASAANAALCHMRDWLFGTKPGDWVSMGIPVPEGNPYGIKPGVIYSFPCTVDKDGKVHIVEGLEINDWVREKMEATEKELIEERETAFKVLAQ 4uyr A 0.89 BS01 MG A 1 H7 G34 T35 S36 S69 H6 G16 T17 S18 S51 P08640 25960408 GSSHHHHHHSSGSSEGTSCNSIVNGCPNLDFNWHMDQQNIMQYTLDVTSVSWVQDNTYQITIHVKGKENIDLKYLWSLKIIGVTGPKGTVQLYGYNENTYLIDNPTDFTATFEVYATQDVNSCQVWMPNFQIQFEYLQGSAAQYASSWQWGTTSFDLSTGCNNYDNQGHSQTDFPGFYWNIDCDNNCG 4uys A 1.05 BS01 MG A 1 G100 V101 T102 P146 N147 F148 G71 V72 T73 P117 N118 F119 P08640 25960408 GSSEGTSCNSIVNGCPNLDFNWHMDQQNIMQYTLDVTSVSWVQDNTYQITIHVKGKENIDLKYLWSLKIIGVTGPKGTVQLYGYNENTYLIDNPTDFTATFEVYATQDVNSCQVWMPNFQIQFEYLQGSAAQYASSWQWGTTSFDLSTGCNNYDNQGHSQTDFPGFYWNIDCDNNCG 4wrl A 2.80 BS01 FUC A 1 P56 H57 T75 Q77 P37 H38 T56 Q58 2.7.10.1 P07333 26235028 IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRAAQIVCSASSVDVNFDVFLQHQNTKLAIPQQSDFHNNRYQKVLTLNLDVDFQHAGNYSCVASNVQGKHSTSMFFRVV 4wrl C 2.80 BS01 FUC C 1 H57 Q77 H38 Q58 2.7.10.1 P07333 26235028 IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHQNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVV 4wtr A 2.27 BS01 BGC A 1 E12 W65 E14 W67 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4wtr A 2.27 BS02 BGC A 2 F38 W65 F230 E235 R238 F40 W67 F232 E237 R240 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4wtr A 2.27 BS03 BGC A 3 E99 Y102 F154 E101 Y104 F156 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4wtr A 2.27 BS04 BGC A 4 Y102 A153 F154 E158 Y104 A155 F156 E160 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4wts A 2.30 BS01 BGC A 1 E12 A39 W65 E14 A41 W67 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4wts A 2.30 BS02 BGC A 2 F38 W65 E235 R238 F40 W67 E237 R240 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4wts A 2.30 BS03 BGC A 3 E99 N152 F154 W157 F230 R238 E242 E101 N154 F156 W159 F232 R240 E244 2.4.1.- GSQTFYGINYGVNENSCPTVDSMKNDFNVLKPYTNRVRTFALSVCNQASLALAATQALGMRIYLGMWIDRPDTFDNEMNALKNILANNDVSNVDGLIVGSEVLYRGDTDPQSLANYIKQVKELVAPHGIKVATADVYYKFPEVVVKELDFLMMNAFPYWEGVTIDNAADTLMSHYDQVVGASLGKPVKISATGWPSAGGNFQSSVASVENENKYLHDVLCRVKQRNIDLLYFSAFDEPYRGGVEAHFGVLGSDRNTKPGITIEAGC 4x2g A 1.51 BS01 3WK A 1 I211 V219 A230 L260 S280 D281 Y282 H283 S287 D290 L340 I13 V21 A32 L62 S82 D83 Y84 H85 S89 D92 L142 2.7.11.30 P36897 25437144 GTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI 4xgk A 2.65 BS01 40K A 1 Q161 W162 R288 S315 Y326 P327 Y364 Q160 W161 R287 S314 Y325 P326 Y363 5.4.99.9 Q6NER4 26214585 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 4xgk A 2.65 BS02 FDA A 1 V9 G10 G12 L13 F14 V33 E34 K35 R36 G41 N42 Y58 A60 H61 L62 T219 D220 W221 F222 G241 P242 Y325 Y326 G357 R358 Y364 L365 D366 M367 A370 V8 G9 G11 L12 F13 V32 E33 K34 R35 G40 N41 Y57 A59 H60 L61 T218 D219 W220 F221 G240 P241 Y324 Y325 G356 R357 Y363 L364 D365 M366 A369 5.4.99.9 Q6NER4 26214585 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 4xgk B 2.65 BS01 40K B 1 Q161 W162 L259 S315 Y326 P327 Y364 Q160 W161 L258 S314 Y325 P326 Y363 5.4.99.9 Q6NER4 26214585 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 4xgk B 2.65 BS02 FDA B 1 V9 G10 G12 L13 F14 V33 E34 K35 R36 G41 N42 Y58 A60 H61 L62 T219 W221 F222 T240 L259 Y325 G357 R358 Y364 L365 D366 M367 A370 V8 G9 G11 L12 F13 V32 E33 K34 R35 G40 N41 Y57 A59 H60 L61 T218 W220 F221 T239 L258 Y324 G356 R357 Y363 L364 D365 M366 A369 5.4.99.9 Q6NER4 26214585 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFHTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEARELIKEQSAEIDSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELPAGNITRLPVRYNFDNRYFNDTYEGLPVDGYAQWLSNMADHENIEVRLDTDWFEVREDLRAQNPEAPVVYTGPLDRYFDYSEGHLGWRTLDFETEVLNTGDFQGTPVMNYNDAEFPYTRIHEFRHFHPEREDRHPKDKTVIMKEYSRFAEEGDEPYYPINTPSDREMLFKYRELADAETESGKVYFGGRLGTYQYLDMHMAIASALSMFDNKLVDALK 4xgq A 2.70 BS01 MG A 1 D4 T5 E40 G98 D99 D5 T6 E41 G99 D100 3.1.-.- P9WF77 26150422 MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKGRHRAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP 4xgq E 2.70 BS01 MG E 1 D4 T5 E40 D99 D5 T6 E41 D100 3.1.-.- P9WF77 26150422 MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKGRHRAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP 4xgr G 2.70 BS01 III H 1 M11 L12 S13 D14 E22 E26 V44 A47 R48 F49 E56 L59 W60 R63 M12 L13 S14 D15 E23 E27 V45 A48 R49 F50 E57 L60 W61 R64 3.1.-.- P9WF77 26150422 MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP 4xgr E 2.70 BS01 III H 1 Y83 K88 N96 Y84 K89 N93 3.1.-.- P9WF77 26150422 MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP 4xgr E 2.70 BS02 III F 1 M11 L12 S13 D14 A18 E19 E22 E26 A47 R48 F49 P52 G53 E56 L59 W60 M12 L13 S14 D15 A19 E20 E23 E27 A48 R49 F50 P53 G54 E57 L60 W61 3.1.-.- P9WF77 26150422 MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP 4xgr C 2.70 BS01 MG C 1 D4 E40 G98 D99 D5 E41 G95 D96 3.1.-.- P9WF77 26150422 MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVA 4xld A 2.45 BS01 BRL A 1 F282 G284 C285 S289 H323 Y327 L330 I341 F363 M364 H449 Y473 F68 G70 C71 S75 H109 Y113 L116 I127 F149 M150 H235 Y259 P37231 MQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTSPFVIYDMNSLMMGEDKIKFKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY 4xn6 A 1.35 BS01 BAM A 1 K33 F34 E35 N37 K33 F34 E35 N37 3.2.1.17 P00698 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4xnc A 2.23 BS01 EA4 A 1 R97 Q105 G114 R124 A143 N144 T149 F155 H168 R54 Q62 G71 R81 A100 N101 T106 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 4xne A 1.80 BS01 TT4 A 1 I29 V37 A50 K52 Q103 D104 M106 L154 I21 V29 A42 K44 Q95 D96 M98 L146 2.7.11.24 P63086 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQP 4xoj A 0.91 BS01 III B 1 F39 C40 H55 S93 N94 T95 L96 Y146 Q170 D186 S187 C188 Q189 G190 D191 S192 S207 W208 G209 S210 G211 G219 F24 C25 H40 S78 N79 T80 L81 Y131 Q155 D171 S172 C173 Q174 G175 D176 S177 S192 W193 G194 S195 G196 G204 3.4.21.4 P00760 26212347 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN 4xoy A 2.10 BS01 DX4 A 1 A50 K52 Q103 D104 M106 L154 C164 A42 K44 Q90 D91 M93 L141 C151 2.7.11.24 P63086 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFDLPKEKLKELIFEETARFQ 4xoz A 1.95 BS01 620 A 1 A50 K52 I54 E69 I70 I101 Q103 D104 M106 A43 K45 I47 E62 I63 I94 Q96 D97 M99 2.7.11.24 P63086 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDLPKEKLKELIFEETARFQP 4xp0 A 1.46 BS01 42A A 1 A50 Q103 D104 L105 M106 A43 Q96 D97 L98 M99 2.7.11.24 P63086 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFDLPKEKLKELIFEETARFQP 4xp2 A 1.75 BS01 TT4 A 1 I29 V37 A50 D104 M106 L154 I22 V30 A43 D97 M99 L147 2.7.11.24 P63086 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFPKEKLKELIFEETARFQ 4xp3 A 1.78 BS01 DX4 A 1 A50 K52 Q103 D104 L105 M106 L154 A43 K45 Q96 D97 L98 M99 L147 2.7.11.24 P63086 GPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFLPKEKLKELIFEETARFQP 4xrj A 1.69 BS01 620 A 1 A50 K52 E69 I101 Q103 D104 M106 A42 K44 E61 I93 Q95 D96 M98 2.7.11.24 P63086 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQP 4xt9 A 2.25 BS01 III B 1 V332 K336 M342 Q346 I350 P500 E504 V68 K72 M78 Q82 I86 P236 E240 P51449 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 4xt9 A 2.25 BS02 43V A 1 C285 Q286 L287 L292 C320 H323 L324 R364 M365 R367 A368 V376 F377 F378 F388 I397 I400 F401 C21 Q22 L23 L28 C56 H59 L60 R100 M101 R103 A104 V112 F113 F114 F124 I133 I136 F137 P51449 ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 4xx0 A 2.10 BS01 COA A 1 G22 T24 G25 K26 Q27 T46 P48 K50 Y79 V80 P81 P82 I103 T104 E105 N131 C132 P133 G21 T23 G24 K25 Q26 T45 P47 K49 Y78 V79 P80 P81 I102 T103 E104 N130 C131 P132 6.2.1.4,6.2.1.5 O19069 SYTASRKHLYVDKNTKVICQGFTGKQGTFHSQQALEYGTNLVGGTTPGKGGKTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAAAAINEAIDAEVPLVVCITEGIPQQDMVRVKHRLLRQGKTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFTDCLEIFLNDPATEGIILIGEIGGNAEENAAEFLKQHNSGPKSKPVVSFIAGLTAPPGRRMGHAGAIIAGGKGGAKEKITALQSAGVVVSMSPAQLGTTIYKEFEKRK 4xzd A 1.70 BS01 HEM A 1 R40 G41 F43 Y55 Y75 F77 H81 F83 M131 H135 H140 R144 M147 R39 G40 F42 Y54 Y74 F76 H80 F82 M130 H134 H139 R143 M146 Q66G68 26210321 STTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPD 4xzd D 1.70 BS01 HEM D 1 R40 G41 F43 Y55 Y75 F77 H81 F83 H135 H140 V143 R144 M147 R39 G40 F42 Y54 Y74 F76 H80 F82 H134 H139 V142 R143 M146 Q66G68 26210321 STTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPD 4y0a A 1.91 BS01 SKM A 1 M27 D50 F73 R74 G95 G96 G97 P135 L136 R153 M17 D40 F63 R64 G85 G86 G87 P125 L126 R143 2.7.1.71 PSKAFETLPNIYLVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTGATIPWIFEKEGEVGFRTRETVVLNELTSRKALVLATGGGAITQAPNREFLKQRGIVVYLYTPVELQLQRTYRDKNRPLLQVENPEQKLRDLLKIRDPLYREVAHYTIETNQGAARDLAQKILQLILSNKLK 4y1q A 3.10 BS01 HEM A 1 R40 G41 F43 F50 Y55 H81 F83 V143 R144 M147 R39 G40 F42 F49 Y54 H80 F82 V142 R143 M146 Q66G68 26210321 STTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKASFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPD 4y1q B 3.10 BS01 HEM B 1 R40 G41 F50 Y55 P79 H81 F83 H140 V143 R144 M147 R39 G40 F49 Y54 P78 H80 F82 H139 V142 R143 M146 Q66G68 26210321 STTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKASFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPD 4y1q G 3.10 BS01 HEM G 1 R40 G41 F43 F50 Y55 F77 P79 H81 F83 V143 R144 M147 R39 G40 F42 F49 Y54 F76 P78 H80 F82 V142 R143 M146 Q66G68 26210321 STTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKASFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPD 4y4s A 1.75 BS01 HEM A 1 G45 T82 F83 H84 G29 T66 F67 H68 Q66G68 26210321 MSTTIQYNSNYADYSISSYLREWANNFGGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKASFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPDSG 4y72 A 2.30 BS01 LZ9 A 1 I10 Y15 V18 A31 K33 V64 F80 E81 F82 L83 S84 D86 K89 L135 D146 I13 Y18 V21 A34 K36 V67 F83 E84 F85 L86 S87 D89 K92 L138 D149 2.7.11.22,2.7.11.23 P06493 25864384 LGSMEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 4ydv L 2.70 BS01 III P 1 Y49 W50 M53 L55 Y45 W46 M49 L51 P01834 26237403 IVLAQSPDSLAVSPGERATIHCKSSQHSIAWYQQRPGQPPKLLLYWASMRLSGVPDRFSGSGSGTDFTLTINNLQAEDVAIYYCHQYSSHPPTFGHGTRVELRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN 4ydv H 2.70 BS01 III P 1 E31 Y32 Y33 K52A A95 D96 G97 L98 T99 Y100 F100A L100D L100E Q100F E31 Y32 Y33 K53 A99 D100 G101 L102 T103 Y104 F105 L108 L109 Q110 S6B291 26237403 QVQLVQSGGGVFKPGGSLRLSCEASGFTFTEYYMTWVRQAPGKGLEWLAYISKNGEYSKYSPSSNGRFTISRDNAKNSVFLQLDRLSADDTAVYYCARADGLTYFSELLQYIFDLWGQGARVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP 4yh8 A 1.70 BS01 ZN A 1 C18 C27 C33 H37 C4 C13 C19 H23 Q09176 26215567 KVNCSFYYKIGACRHGERCSRKHVKPNFSQTILCPNMYKNPIHEPNGKKFTQRELAEQFDAFYEDMFCEFSKYGEVEQLVVCDNVGDHLVGNVYVRFKYEESAQNAIDDLNSRWYSQRPVYAELSPVTDFREACCRQHETSECQRGGLCNFMHAKKPSPQLLRDLVLAQRKYLALNAAEE 4yix A 2.60 BS01 MG A 1 S320 D409 D411 V456 S258 D347 D349 V394 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yix A 2.60 BS02 MG A 2 C570 C620 C490 C534 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yix A 2.60 BS03 MG A 3 C570 L574 C620 I651 C490 L494 C534 I565 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yix A 2.60 BS04 ADP A 1 P263 A277 V278 F316 H317 G318 K319 S320 T321 Y476 P201 A215 V216 F254 H255 G256 K257 S258 T259 Y414 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yiy B 3.02 BS01 ANP B 1 P263 L273 A277 V278 G314 G315 F316 H317 G318 K319 S320 T321 D411 Y476 P200 L210 A214 V215 G251 G252 F253 H254 G255 K256 S257 T258 D348 Y412 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yiy B 3.02 BS02 ANP A 1 D384 S386 G387 S388 D321 S323 G324 S325 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yiy B 3.02 BS03 MG A 1 D355 S386 G387 D292 S323 G324 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGEPRIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yiy A 3.02 BS01 ANP B 1 D384 S386 G387 S388 N416 D321 S323 G324 S325 N353 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGERIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yiy A 3.02 BS02 MG B 1 S386 G387 S323 G324 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGERIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yiy A 3.02 BS03 ANP A 1 P263 L273 V278 G315 F316 G318 K319 S320 T321 Y476 P200 L210 V215 G252 F253 G255 K256 S257 T258 Y413 Q57ZF2 26117548 SPLMDFFHSVEGRNYGELRSLTNETYQISENVRCTFLSIQSDPFAPGSQVRLVCPCTFSLEKVLQTTDLAAANPCRRVAAEDFILRSFHAGYRNGIPRRTSGAVQVLRPSQHVLERSTVGLVKEIEIFARVKLPGRRIDGHGAIDIFYNELVPLLEQCVVGLNEEDLHQHVICVHDQEELRSNLLGAGYVAFVANGAILPRDAGNSDKPLRDNAVPFQSPKSLECSFTLPHSGKTITGMGLPPGLTLIAGGGFHGKSTLLRALEVGIYNHVPDDGRTYVVVDPTAVKIRAEDRRSVHGVDISPFINNLPFGKTTNFFVTADASGSTSQAANIMEALELGSQLLLLDEDTCATNLMYRDALMQMLVPRAQEPITPFVERVADLSQNHGVSSIMVIGGSGQYFPQARVVLVMNAYQISDCTKEAKEIASNSSSVFIPDVNRCFDPDGSFTTVRTKVSGIGTESIRFSEETIDLSMVEQIVEEGQVNAIAQCLALLYDGERIVPEMTTKGGALTQLPSPGGVCFNSNFSSMIAGCCSHQHDKRLELRTPSCYLPRGFTSATRHIEIGAALNRLRTLRTVT 4yp0 A 2.10 BS02 5IQ A 1 P125 C154 W155 R156 R165 R166 E167 H168 P79 C108 W109 R110 R114 R115 E116 H117 6.1.1.21 Q4DA54 NMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4ypf A 2.20 BS02 4FS A 1 P125 W155 R156 R166 E167 H168 P78 W108 R109 R114 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEREEVEAQLAVTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrc A 2.10 BS03 0P6 A 2 V383 V384 G433 V435 V335 V336 G385 V387 6.1.1.21 Q4DA54 NMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYEAITRRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRRGFAVPLDRLV 4yre A 2.25 BS02 4HR A 1 I106 P125 C154 W155 R156 R165 R166 E167 H168 I60 P79 C108 W109 R110 R113 R114 E115 H116 6.1.1.21 Q4DA54 NMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYRRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrg A 2.15 BS02 4HU A 1 P125 C154 W155 R156 R165 E167 H168 P78 C107 W108 R109 R113 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGTSDKFAPVCVIVDKMPREEVEAQLAVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrj A 2.30 BS02 4JJ A 1 I106 P125 C154 W155 R156 R165 E167 H168 I59 P78 C107 W108 R109 R113 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrk B 2.20 BS02 4JL B 1 I106 P125 W155 R156 R165 R166 E167 H168 I59 P78 W108 R109 R113 R114 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEEEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRRGFAVPLDRLV 4yrl A 2.30 BS02 4JM A 1 P125 W155 R156 R165 R166 E167 H168 P78 W108 R109 R113 R114 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrp A 2.20 BS02 PZH A 1 C154 W155 R156 R166 E167 H168 C107 W108 R109 R114 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKEEVEAQLAVLGPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRRGFAVPLDRLV 4yrp B 2.20 BS02 PZH B 1 C154 W155 R156 E167 H168 C107 W108 R109 E115 H116 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrr A 2.30 BS02 691 A 1 C154 W155 R156 R165 E167 H168 C365 C107 W108 R109 R111 E113 H114 C309 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4yrs A 2.75 BS01 HIS A 1 E126 T128 D174 L316 Y318 Y319 Y342 G359 F360 G361 E79 T81 D125 L267 Y269 Y270 Y293 G310 F311 G312 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYEAITRRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRRGFAVPLDRLV 4yrs A 2.75 BS02 4JS A 1 P125 C154 W155 R156 R165 E167 H168 C365 P78 C107 W108 R109 R116 E118 H119 C316 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYEAITRRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRRGFAVPLDRLV 4yrt A 2.05 BS02 781 A 1 C154 W155 R156 R166 E167 H168 C365 V366 C107 W108 R109 R114 E115 H116 C313 V314 6.1.1.21 Q4DA54 MVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYERRREHYQWNMDIVGVKSVSAEVELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYTGIVFEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLRGFAVPLDRLV 4ytc A 2.16 BS01 4HW A 1 L855 V863 A880 V911 M929 E930 Y931 L932 G935 R980 L983 D994 L14 V20 A37 V68 M85 E86 Y87 L88 G91 R136 L139 D150 2.7.10.2 O60674 26230873 TQFEERHLKFLQQLGKGGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSARRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 4ytf A 1.78 BS01 4HZ A 1 L855 G856 V863 A880 M929 E930 Y931 L932 G935 R980 N981 L983 G993 L14 G15 V20 A37 M84 E85 Y86 L87 G90 R135 N136 L138 G148 2.7.10.2 O60674 26230873 TQFEERHLKFLQQLGKGGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 4yth A 2.04 BS01 467 A 1 L855 G856 V863 A880 M929 E930 Y931 L932 G935 R980 N981 I982 L983 G993 D994 L14 G15 V22 A39 M88 E89 Y90 L91 G94 R139 N140 I141 L142 G152 D153 2.7.10.2 O60674 26230873 TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 4yti A 2.52 BS01 VJK A 1 G856 V863 A880 V911 E930 Y931 L932 G935 S936 R980 N981 L983 G993 D994 G15 V22 A39 V70 E86 Y87 L88 G91 S92 R136 N137 L139 G149 D150 2.7.10.2 O60674 26230873 TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 4z5q A 1.80 BS01 HEM A 1 L90 H97 R101 F108 I237 G240 G241 T244 E248 I291 S292 R294 V344 F345 G346 H350 C352 G354 L357 A358 L64 H71 R75 F82 I211 G214 G215 T218 E222 I265 S266 R268 V318 F319 G320 H324 C326 G328 L331 A332 Q8GGM6 PAPVAYPFDGDPIRVQLPFGEPAWLVTRYDDARFVLTDRRFSRHLATQRDEPRMTPRAVPESILTMDPPDHTRLRTLVSKAFTPRRIESKRAWIGELAAGLVADMKAGGAPAELVGSYALAIPVTVICELLGVPEDDRTRLRGWCDAALSTGELTDEECVQSFMDLQKYFEDLVKERRAEPRDDLTSALIEARDAHDRLAEPELIGLCISILIGGFETTASEISSFVHVLQQRRELWTRLCADPEAIPAAVEELLRFVPFAANGISPRYALEDMTVGGVLVREGEPVIVDTSAVNRDGLVFDNADEVVIDRADNRHMVFGHGAHHCLGAHLARVELQEALKALVEGMPGLRLSGAPRVMHVEW 4zjv A 2.70 BS01 III C 1 W905 T909 Y915 I918 I926 L927 E928 K929 G930 E931 R932 P934 Q935 P936 P937 I938 C939 T940 I941 Y944 V948 K949 W951 M952 I953 R977 V980 W202 T206 Y212 I215 I223 L224 E225 K226 G227 E228 R229 P231 Q232 P233 P234 I235 C236 T237 I238 Y241 V245 K246 W248 M249 I250 R274 V277 2.7.10.1 P00533 LLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDE 4zjv A 2.70 BS02 III C 2 K875 I878 S921 K172 I175 S218 2.7.10.1 P00533 LLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDE 4zjv A 2.70 BS03 III C 3 R841 G874 K875 V876 P877 K879 I886 R889 P919 A920 R138 G171 K172 V173 P174 K176 I183 R186 P216 A217 2.7.10.1 P00533 LLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDE 4zjv B 2.70 BS01 III D 1 W905 I918 L927 E928 G930 E931 R932 P934 Q935 P936 P937 I938 C939 T940 Y944 V948 K949 M952 I953 V980 W196 I209 L218 E219 G221 E222 R223 P225 Q226 P227 P228 I229 C230 T231 Y235 V239 K240 M243 I244 V271 2.7.10.1 P00533 LLRILKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELTSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQ 4zjv B 2.70 BS02 III D 2 I878 L887 A920 I169 L178 A211 2.7.10.1 P00533 LLRILKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELTSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQ 4zjv B 2.70 BS03 III D 3 G873 G874 K875 V876 P877 K879 I886 R889 P919 A920 G164 G165 K166 V167 P168 K170 I177 R180 P210 A211 2.7.10.1 P00533 LLRILKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELTSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQ 4zo5 A 2.50 BS03 4PX A 1 Y514 H515 L625 D664 L665 V668 A679 I682 F686 M703 Q716 F719 Y78 H79 L189 D228 L229 V232 A243 I246 F250 M267 Q280 F283 3.1.4.17,3.1.4.35 Q9Y233 26077491 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4zo5 B 2.50 BS03 4Q0 B 1 L625 L665 V668 I682 Y683 F686 P702 M703 E711 V712 G715 Q716 G718 F719 V723 L189 L229 V232 I246 Y247 F250 P266 M267 E275 V276 G279 Q280 G282 F283 V287 3.1.4.17,3.1.4.35 Q9Y233 26077491 HMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4zph A 2.80 BS01 PRL A 1 R266 V305 R121 V129 P53762 ERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSRRSFICRMRCPHFVVVHCTGYIKAFCLVAIGRLQVPTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKTREWLWMRTSSFTFQNPYSDEIEYIICTNTNV 4zph B 2.80 BS01 PRL A 1 Q306 L344 S345 Q237 L275 S276 P97481 RRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLSTERDFFMRMKCTVGRTVNLKSATWKVLHCTGQVRVLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTES 4zpk A 3.60 BS01 NUC C 1 R91 H94 E98 R99 R102 T106 D127 K128 R5 H8 E12 R13 R16 T20 D41 K42 P53762 ERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSRRSFICRMRCGTPHFVVVHCTGYIKFCLVAIGRLQVTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKTREWLWMRTSSFTFQNPYSDEIEYIICTNTNV 4zpk A 3.60 BS02 NUC D 1 H94 E98 R101 H8 E12 R15 P53762 ERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSRRSFICRMRCGTPHFVVVHCTGYIKFCLVAIGRLQVTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKTREWLWMRTSSFTFQNPYSDEIEYIICTNTNV 4zpk B 3.60 BS01 NUC C 1 L14 K18 R26 N184 K186 L7 K11 R19 N164 K166 P97481 KRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNLQPQCIMCVNYVLSEIKNDVVFSMDQTE 4zpk B 3.60 BS02 NUC D 1 K16 S19 R20 A23 R24 R27 T31 D52 K53 K9 S12 R13 A16 R17 R20 T24 D45 K46 P97481 KRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNLQPQCIMCVNYVLSEIKNDVVFSMDQTE 4zpr A 3.90 BS01 NUC C 1 R91 H94 S95 E98 R99 R102 D127 K128 R5 H8 S9 E12 R13 R16 D39 K40 P53762 ERLARENHSEIERRRRNKMTAYITELSDMVPTALARKPDKLTILRMAVSHMKSLTDQELKHLILEAADGFLFIVSGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSRRSFICRMRCVHCTGYVAIGRLQTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFWMRTSSFTFQNPYSDEIEYIICTNTNV 4zpr A 3.90 BS02 NUC D 1 H94 E98 R101 R102 H8 E12 R15 R16 P53762 ERLARENHSEIERRRRNKMTAYITELSDMVPTALARKPDKLTILRMAVSHMKSLTDQELKHLILEAADGFLFIVSGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSRRSFICRMRCVHCTGYVAIGRLQTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFWMRTSSFTFQNPYSDEIEYIICTNTNV 4zpr B 3.90 BS01 NUC C 1 R18 K21 R29 N183 R4 K7 R15 N138 Q61221 SERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDCFYLKALDGFVMVLTDDGDMVYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTTQRSFFLRMKCTLTRTMNIKSATWKVLHCTGHIHCLVLICEPIPHPSNIESKTFLSRHSLDMKFSYCDITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHD 4zpr B 3.90 BS02 NUC D 1 K19 S22 R23 R27 R30 D55 K56 K5 S8 R9 R13 R16 D41 K42 Q61221 SERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDCFYLKALDGFVMVLTDDGDMVYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTTQRSFFLRMKCTLTRTMNIKSATWKVLHCTGHIHCLVLICEPIPHPSNIESKTFLSRHSLDMKFSYCDITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHD 4zqd B 2.87 BS01 0X3 B 1 F244 S246 H248 M252 F254 A277 F280 Y281 Y307 M309 T321 C339 N341 F172 S174 H176 M180 F182 A205 F208 Y209 Y235 M237 T249 C267 N269 P97481 RRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLSTERDFFMRMKCTVTVNLKSATWKVLHCTGQVRVSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTES 4zsc A 1.50 BS01 EA4 A 1 R97 F102 Q105 G114 R124 A143 N144 T149 Q153 F155 H168 R54 F59 Q62 G71 R81 A100 N101 T106 Q110 F112 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 4zsd A 1.45 BS01 7I6 A 1 R97 F102 M103 Q105 G114 R124 A143 N144 T149 F155 L164 H168 R54 F59 M60 Q62 G71 R81 A100 N101 T106 F112 L121 H125 5.2.1.8 P30405 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 4zzx A 1.65 BS01 FSU A 1 S328 I331 H428 G429 G454 Y462 F463 K469 S470 Y473 E558 S98 I101 H198 G199 G224 Y232 F233 K239 S240 Y243 E326 2.4.2.30 Q9UGN5 26222319 ESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 4zzy A 2.20 BS01 D7N A 1 S328 I331 Q332 H428 G429 G454 Y455 Y462 F463 A464 K469 S470 Y473 E558 S98 I101 Q102 H198 G199 G224 Y225 Y232 F233 A234 K239 S240 Y243 E326 2.4.2.30 Q9UGN5 26222319 ESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 4zzz A 1.90 BS01 FSU A 1 H862 G863 Y896 F897 S904 Y907 E988 H198 G199 Y232 F233 S240 Y243 E324 2.4.2.30 P09874 26222319 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW 4zzz B 1.90 BS01 FSU B 1 H862 G863 Y896 F897 A898 K903 S904 Y907 E988 H193 G194 Y227 F228 A229 K234 S235 Y238 E319 2.4.2.30 P09874 26222319 KLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT 5a00 A 2.75 BS01 D7N A 1 Q759 V762 H862 G863 T887 Y889 Y896 F897 A898 K903 S904 Y907 E988 Q93 V96 H192 G193 T217 Y219 Y226 F227 A228 K233 S234 Y237 E318 2.4.2.30 P09874 26222319 KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK 5a81 A 2.03 BS01 78J A 1 V1008 V1013 N1064 G1070 D1071 I1074 R1077 V30 V35 N86 G92 D93 I96 R99 3.6.1.3 Q6PL18 26230603 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 5a82 A 1.86 BS01 YEJ A 1 R1007 V1008 V1013 E1017 V1018 Y1063 N1064 G1070 D1071 I1074 R1077 R29 V30 V35 E39 V40 Y85 N86 G92 D93 I96 R99 3.6.1.3 Q6PL18 26230603 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 5a83 A 2.09 BS01 YD3 A 1 V1008 V1013 D1014 E1017 V1018 Y1063 N1064 G1070 D1071 I1074 R1077 V30 V35 D36 E39 V40 Y85 N86 G92 D93 I96 R99 3.6.1.3 Q6PL18 26230603 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 5a85 A 1.72 BS01 78J A 1 V87 L92 L94 N140 D144 I146 M149 V46 L51 L53 N99 D103 I105 M108 O60885 26230603 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTE 5bqy A 2.78 BS01 SIA A 1 Y91 S129 G130 V131 S132 S133 W149 H180 E187 L191 Q223 Y91 S129 G130 V131 S132 S133 W149 H180 E187 L191 Q223 A0A067Z050 26226046 DKICIGYHANNSTTKVDTILEKNVTVTHSVELLENQKEERFCKISNKAPLDLRDCTLEGWILGNPRCGILLADQSWSYIVERPNARNGICYPGTLNEAEELKALIGSGERVERFEMFPKSTWTGVNTESGVSSACPLGNGPSFYRNLLWIIKLKSSEYPVIRGTFNNTGDKSILYFWGVHHPPVTTEQNALYGSGDRYVRMGTESMNFARSPEIAARPAVNGQRGRIDYFWSILKPGETLNVESNGNLIAPWYAYRFVNKDSKGAIFRSNLPIENCDATCQTTEGVIRTNKTFQNVSPLWIGECPKYVKSKSLRLATGLRNVPQ 5br3 A 2.55 BS01 SIA A 1 Y91 R129 V131 T132 N133 W150 H181 L192 Q224 S226 Y91 R129 V131 T132 N133 W150 H181 L192 Q224 S226 26226046 DKICIGYHANNSTTQVDTLLEKNVTVTHSVELLENQKEKRFCKIMNKAPLDLKDCTIEGWILGNPKCDLLLGDQSWSYIVERPNAQNGICYPGVLNELEELKAFIGSGERVERFEMFPKSTWAGVDTSRGVTNACPSYTIDSSFYRNLVWIVKTDSATYPVIKGTYNNTGTQPILYFWGVHHPLDTTVQDNLYGSGDKYVRMGTESMNFAKSPEIAARPAVNGQRSRIDYYWSVLRPGETLNVESNGNLIAPWYAYKFVSTNKKGAVFKSDLPIENCDATCQTITGVLRTNKTFQNVSPLWIGECPKYVKSESLRLATGLRNVPQI 5br6 A 2.43 BS02 GAL A 1 N133 Q224 N133 Q224 26226046 DKICIGYHANNSTTQVDTLLEKNVTVTHSVELLENQKEKRFCKIMNKAPLDLKDCTIEGWILGNPKCDLLLGDQSWSYIVERPNAQNGICYPGVLNELEELKAFIGSGERVERFEMFPKSTWAGVDTSRGVTNACPSYTIDSSFYRNLVWIVKTDSATYPVIKGTYNNTGTQPILYFWGVHHPLDTTVQDNLYGSGDKYVRMGTESMNFAKSPEIAARPAVNGQRSRIDYYWSVLRPGETLNVESNGNLIAPWYAYKFVSTNKKGAVFKSDLPIENCDATCQTITGVLRTNKTFQNVSPLWIGECPKYVKSESLRLATGLRNVPQI 5bv3 A 2.25 BS01 M7G A 1 K126 W161 E171 P193 D194 M195 K196 H259 P262 S263 Y264 H270 K114 W147 E157 P177 D178 M179 K180 H243 P246 S247 Y248 H254 3.6.1.59 Q06151 MFASLIKRFQFVSVLDSNPQTKVMSLLGTIDNKDAIITAEKTHFLFDETDGRSTPVLYNCENEYSCINGIQELKEITSNDIYYWGLSVIKQDMESNPTAKLNLIWPATPIHIKKYEQQNFHLVRETPEMYKRIVQPYIEEMCGRLKWVNNILYEGAESERVVYKDFSEKDDGFLILPDMKWDGMNLDSLYLVAIVYRTDIKTIRDLRYSDRQWLINLNNKIRSIVPGCYNYAVHPDELRILVHYQPSYYHFNIHIVNIKHPGLGNSIAAGKAILLEDIIEMLNYLGPEGYMNKTITYAIGENHDLWKRGLEEELTKQLERDGIPKIPKI 5bv3 B 2.25 BS01 M7G A 1 N91 Y94 W96 N75 Y78 W80 3.6.1.59 Q06151 GMFASLIKRFQFVSVLDSNPQTKVMSLLGTIDNKDAIITAEKTHFLFDETPVLYNCENEYSCINGIQELKEITSNDIYYWGLSVIKQDMESNPTAKLNLIWPATPIHIKKYEQQNFHLVRETPEMYKRIVQPYIEEMWVNNILYEGAESERVVYKDFSEENKDDGFLILPDMNLDSLYLVAIVYRTDIKTIRDLRYSDRQWLINLNNKIRSIVPGCYNYAVHPDELRILVHYQPSYYHFNIHIVNIKHPGLGNSIAAGKAILLEDIIEMLNYLGPEGYMNKTITYAIGENHDLWKRGLEEELTKQLERDGIPKIPK 5bvn A 2.21 BS01 4VD A 1 L616 V624 A653 V654 K655 E672 I675 M676 L679 I685 M699 T701 D702 Y703 M704 G707 F762 L773 A783 D784 F785 L13 V21 A34 V35 K36 E53 I56 M57 L60 I66 M80 T82 D83 Y84 M85 G88 F129 L140 A150 D151 F152 2.7.10.1 Q08345 26191369 DFPRSRLRFKEKLGEGQFGEVHLCEVDSHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALN 5c0k A 2.20 BS02 4WK A 1 L307 T308 D309 W310 E314 Q319 W323 L59 T60 D61 W62 E66 Q71 W75 6.3.2.- P98170 26218264 NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECL 5c0l A 2.60 BS02 4WJ A 1 L307 T308 D309 E314 Q319 W323 Y324 L59 T60 D61 E66 Q71 W75 Y76 6.3.2.- P98170 26218264 NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 5c3k A 2.02 BS02 4XF A 1 G306 L307 T308 D309 W310 E314 Q319 W323 G58 L59 T60 D61 W62 E66 Q71 W75 6.3.2.- P98170 26218264 NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 5c5p A 1.75 BS01 ZN A 1 C1081 H1084 C1089 C1092 C130 H133 C138 C141 2.4.2.30 Q9H2K2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5c5p A 1.75 BS02 0E0 A 1 H1031 G1032 P1034 H1048 Y1050 Y1060 A1062 K1067 S1068 Y1071 H80 G81 P83 H97 Y99 Y109 A111 K116 S117 Y120 2.4.2.30 Q9H2K2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5c5q A 2.00 BS02 G9W A 1 H1031 G1032 P1034 A1049 Y1050 Y1060 A1062 K1067 S1068 Y1071 H80 G81 P83 A98 Y99 Y109 A111 K116 S117 Y120 2.4.2.30 Q9H2K2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSA 5c5q B 2.00 BS02 G9W B 1 H1031 G1032 P1034 Y1050 Y1060 A1062 K1067 S1068 Y1071 H80 G81 P83 Y99 Y109 A111 K116 S117 Y120 2.4.2.30 Q9H2K2 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFS 5c83 A 2.33 BS02 4YN A 1 M248 L292 K297 V298 G306 L307 T308 D309 W310 K311 E314 Q319 W323 Y324 M1 L45 K50 V51 G59 L60 T61 D62 W63 K64 E67 Q72 W76 Y77 6.3.2.- P98170 26218264 MNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR 5c8q B 1.90 BS01 NAG B 1 T65 R67 F77 E89 D90 T65 R67 F77 E89 D90 L7JBY8 GNYAGNFSGSSRDICLDGARLRAECRRGDGGYSTSVIDLNRYLSNDNGHFRWVSTATVTVQQGDTLRDIGRRFDCDFHEIARRNNIQNEDLIYPGQVLQVGGNFWDSARDVRLVDGGKVLEAELRYSGGWNRSRIYLDEHIGNRNGELIHC 5c8q B 1.90 BS02 NAG B 2 D64 D90 L91 I92 D64 D90 L91 I92 L7JBY8 GNYAGNFSGSSRDICLDGARLRAECRRGDGGYSTSVIDLNRYLSNDNGHFRWVSTATVTVQQGDTLRDIGRRFDCDFHEIARRNNIQNEDLIYPGQVLQVGGNFWDSARDVRLVDGGKVLEAELRYSGGWNRSRIYLDEHIGNRNGELIHC 5c8q B 1.90 BS03 NAG B 3 Q61 Q62 G63 D64 I92 Y93 P94 Q61 Q62 G63 D64 I92 Y93 P94 L7JBY8 GNYAGNFSGSSRDICLDGARLRAECRRGDGGYSTSVIDLNRYLSNDNGHFRWVSTATVTVQQGDTLRDIGRRFDCDFHEIARRNNIQNEDLIYPGQVLQVGGNFWDSARDVRLVDGGKVLEAELRYSGGWNRSRIYLDEHIGNRNGELIHC 5ccg C 3.50 BS01 CA C 1 D58 E61 D50 E53 P60881 NELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDMKEAEKNLKDLG 5ccg E 3.50 BS01 CA E 1 D303 D309 D363 Y364 D365 D163 D169 D223 Y224 D225 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg E 3.50 BS02 CA E 2 D172 D230 F231 D232 D32 D90 F91 D92 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg E 3.50 BS03 CA E 3 D172 D178 R233 D32 D38 R93 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg E 3.50 BS04 CA E 4 M302 D303 D363 D365 M162 D163 D223 D225 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg F 3.50 BS01 CA F 1 D172 S177 D178 D230 F231 D232 D32 S37 D38 D90 F91 D92 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg F 3.50 BS02 CA F 2 D172 D230 D232 D32 D90 D92 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg F 3.50 BS03 CA F 3 D303 D309 Y364 D365 D161 D165 Y220 D221 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg F 3.50 BS04 CA F 4 D150 Y151 F153 F252 G253 D10 Y11 F13 F112 G113 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg K 3.50 BS01 CA K 1 M302 D303 G306 L307 S308 D363 M162 D163 G166 L167 S168 D223 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5ccg K 3.50 BS03 CA K 3 D172 S177 D178 D230 F231 D32 S37 D38 D90 F91 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 5cch E 3.60 BS01 CA E 1 D303 S308 D309 D363 Y364 D365 D163 S168 D169 D223 Y224 D225 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVK 5cch E 3.60 BS03 CA E 3 D172 D178 D230 F231 D232 D32 D38 D90 F91 D92 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVK 5cch F 3.60 BS03 CA F 3 S308 D309 Y364 S159 D160 Y215 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEKLGDICFSLRYVPTAGKLTVVILEAKNLKKSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 5cch F 3.60 BS04 CA F 4 S308 D363 Y364 D365 S159 D214 Y215 D216 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEKLGDICFSLRYVPTAGKLTVVILEAKNLKKSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 5cci F 4.10 BS02 MG F 2 M302 D363 D365 M156 D212 D214 P21707 KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKGDICFSLRYVPTAGKLTVVILEAKNLKKMSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVK 5cgc A 3.10 BS01 51D A 1 G624 I625 G628 I651 S654 P655 S658 L904 W945 F948 S965 V966 S969 A970 G57 I58 G61 I84 S87 P88 S91 L321 W362 F365 S382 V383 S386 A387 3.2.1.17 P41594 26225459 SPVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTYRAARILAMSKKNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKISACAQLVIAFILICIQLGIIVALFIMEPPDIMVYLICNTTNLGVVAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERN 5cgd A 2.60 BS01 51E A 1 G624 I625 I651 S654 P655 S658 Y659 L904 W945 F948 M962 S965 V966 S969 A970 A973 G57 I58 I84 S87 P88 S91 Y92 L321 W362 F365 M379 S382 V383 S386 A387 A390 3.2.1.17 P41594 26225459 SPVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTYRAARILAMSKKNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKISACAQLVIAFILICIQLGIIVALFIMEPPDIMVYLICNTTNLGVVAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPER 5cix A 1.88 BS01 211 A 1 V69 Y70 I71 M72 E85 G109 Y111 I155 A159 R163 V69 Y70 I71 M72 E85 G109 Y111 I155 A159 R163 3.2.2.22 D9J2T9 DVSFRLSGADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLMHLFNYDGNTITVAVDVTNVYIMGYLALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDTAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSSATISLENSWSGLSKQIQLAQGNNGVFRTPTVLVDSKGNRVQITNVTSNVVTSNIQLLLNTKNI 5clt A 2.79 BS01 ACR A 1 N62 E63 W91 P93 Y119 G120 K121 W332 E333 R336 N19 E20 W48 P50 Y76 G77 K78 W289 E290 R293 2.4.1.18 Q04446 DFQRRYKQFSQILKNIGENEGGIDKFSRGYESFGVHRCADGGLYCKEWAPGAEGVFLTGDFNGWNPFSYPYKKLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEILYRISPWAKYVVREGDNVNYDWIHWDPEHSYEFKHSRPKKPRSLRIYESHVGISSHEGKVASYKHFTCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGSPEELQELVDTAHSMGIIVLLDVVHSHASKNSADGLNMFDGTDSCYFHSGPRGTHDLWDSRLFAYSSWEVLRFLLSNIRWWLEEYRFDGFRFDGVTSMLYHHHSEYFGLQVDEDALTYLMLANHLVHTLCPDSITIAEDVSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAESHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKHEGNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEAFEHNGRPYSLLVYIPSRVALILQNVD 5cmn E 3.61 BS01 CA E 1 D264 N312 A313 V367 D368 D131 N179 A180 V223 D224 Q9HAR2 26235030 LCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDF 5cmn F 3.61 BS01 CA F 1 D264 N312 A313 V367 D131 N179 A180 V223 Q9HAR2 26235030 LCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDF 5coe B 2.18 BS01 EPE B 1 R181 E183 G185 G186 W188 F190 R197 Y198 R145 E147 G149 G150 W152 F154 R161 Y162 P14210 NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEV 5cp9 B 1.90 BS01 6O5 B 1 F162 R181 E183 W188 F190 R197 Y198 F126 R145 E147 W152 F154 R161 Y162 P14210 NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEV 5cpf A 3.41 BS02 53K A 1 G96 F97 M98 M103 M155 P156 A157 Y158 P193 M199 G94 F95 M96 M101 M153 P154 A155 Y156 P191 M197 1.3.1.9 P9WGR0 26147157 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQAQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5cpf B 3.41 BS02 53K B 1 G96 F97 M98 M103 F149 M155 P156 A157 Y158 M161 P193 A198 M199 I202 L218 G94 F95 M96 M101 F147 M153 P154 A155 Y156 M159 P191 A196 M197 I200 L216 1.3.1.9 P9WGR0 26147157 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQAQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5cpf C 3.41 BS02 53K C 1 G96 F97 M98 M103 F149 P156 A157 Y158 M161 P193 L218 G94 F95 M96 M101 F147 P154 A155 Y156 M159 P191 L216 1.3.1.9 P9WGR0 26147157 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQAQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5cpf D 3.41 BS01 53K D 1 G96 F97 M98 F149 M155 P156 A157 Y158 M161 A198 M199 I202 V203 G94 F95 M96 F147 M153 P154 A155 Y156 M159 A196 M197 I200 V201 1.3.1.9 P9WGR0 26147157 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQAQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5cr5 A 1.61 BS01 PLP A 1 R99 R192 K202 Y207 E237 T240 N242 L266 G268 V269 V270 G312 T313 R92 R185 K195 Y200 E230 T233 N235 L259 G261 V262 V263 G305 T306 2.6.1.42 O15382 SSFKAADLQLEMTQKPHKKPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 5cr5 A 1.61 BS02 EL1 A 1 F30 F75 R143 Y173 V182 Q224 V238 G239 T240 M241 G310 G312 A314 C318 V320 F23 F68 R136 Y166 V175 Q217 V231 G232 T233 M234 G303 G305 A307 C311 V313 2.6.1.42 O15382 SSFKAADLQLEMTQKPHKKPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV 5cr9 A 1.70 BS01 GLU A 1 S114 H116 Y220 Y229 Y231 R256 V257 F311 S75 H77 Y176 Y185 Y187 R212 V213 F267 C7MWN7 HFPLTITNCGVDVTFDGPPERIILLESAPVATMRALGVLDSVVLRAGAFPPEYYDAETNAALRAIPSLGEELDSSGHLQISEEVIIAQQPDLVLGLPDGVTREGLEAVGINVLVQPTMCPGGVGATTFDDVYEQINTYGRLFDRQDRAAELVASLRQRVAAVEKAVEKRRSAAVLYPTIGGGVGYAYGNESMAHPQLESAGFTNVYADVDERVFEVTLEDVLEQDPDVLVLLHVDGDPDAVKDAVVNLPGADALTAVRNDDILVQLFNFTEPPTPLSVDGLERIHETFGA 5cs3 B 2.50 BS01 EP1 B 1 F162 E183 W188 F190 R197 Y198 V200 F126 E147 W152 F154 R161 Y162 V164 P14210 NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEV 5cs5 B 1.90 BS01 PIN B 1 F162 R181 E183 G185 G186 W188 F190 R197 Y198 F126 R145 E147 G149 G150 W152 F154 R161 Y162 P14210 NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEV 5csq A 1.95 BS01 MPO A 1 F162 E183 W188 F190 R197 Y198 F125 E146 W151 F153 R160 Y161 P14210 TIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE 5cst A 1.78 BS01 CDP A 1 Y70 I71 F83 E85 G109 N110 Y111 E112 I155 R163 Y70 I71 F83 E85 G109 N110 Y111 E112 I155 R163 3.2.2.22 D9J2T9 DVSFRLSGADPSSYGMFIKDLRNALPHTEKVYNIPLLLPSVSGAGRYLLMHLFNYDGNTITVAVDVTNVYIMGYLALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYERLQIAAGKPREKIPIGLPALDTAISTLLHYDSTAAAGALLVLIQTTAEAARFKYIEQQIQERAYRDEVPSSATISLENSWSGLSKQIQLAQGNNGVFRTPTVLVDSKGNRVQITNVTSNVVTSNIQLLLNTKNI 5csz H 1.80 BS01 III D 1 Y32 A33 M34 A50 I51 N52 A53 R57 Y59 Y60 K65 K100 G101 Y109 V110 Y31 A32 M33 A49 I50 N51 A52 R56 Y58 Y59 K64 K99 G100 Y101 V102 21955818 VELVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAINASGTRTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGKGYVRYFDVWGQGTLVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 5csz L 1.80 BS01 III D 1 I92 Y93 N94 M95 P96 I97 I92 Y93 N94 M95 P96 I97 21955818 DIVLTQSPATLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGVPARFSGSGSGTDFTLTISSLEPEDFATYYCLQIYNMPITFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG 5csz A 1.80 BS01 III E 1 Y32 A33 M34 S35 W47 A50 I51 N52 A53 R57 Y59 Y60 G101 Y109 V110 Y31 A32 M33 S34 W46 A49 I50 N51 A52 R56 Y58 Y59 G100 Y101 V102 21955818 VELVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAINASGTRTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARGKGYVRYFDVWGQGTLVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 5ct1 B 2.00 BS01 NHE B 1 E183 W188 F190 R197 Y198 E147 W152 F154 R161 Y162 P14210 NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEV 5ct2 A 2.00 BS01 CXS A 1 E183 E184 W188 F190 R197 Y198 V200 E146 E147 W151 F153 R160 Y161 V163 P14210 TIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE 5ct2 B 2.00 BS01 CXS B 1 F162 E183 E184 W188 F190 R197 Y198 V200 F126 E147 E148 W152 F154 R161 Y162 V164 P14210 NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEV 5cvi A 2.80 BS01 ZN A 1 D7 E99 E102 H103 D5 E97 E100 H101 Q9KIJ2 PNKEDYLKIIYELSERDEKISNKQIAEKMSVSAPAVSEMVKKLLLEDLVLKDKQAGYLLTKKGQILASSLYRKHRLIEVFLMNHLNYTADEIHEEAEVLEHTVSDVFVERLDKFLNYPKVCPHGGTIPQHGQPLVERYRTTLKGVTEMGVYLLKRVQDNFQLLKYMEQHHLKIGDELRLLEYDAFAGAYTIEKDGEQLQVTSAVASQIYIEK 5cvi A 2.80 BS02 ZN A 2 E80 C123 H125 E78 C121 H123 Q9KIJ2 PNKEDYLKIIYELSERDEKISNKQIAEKMSVSAPAVSEMVKKLLLEDLVLKDKQAGYLLTKKGQILASSLYRKHRLIEVFLMNHLNYTADEIHEEAEVLEHTVSDVFVERLDKFLNYPKVCPHGGTIPQHGQPLVERYRTTLKGVTEMGVYLLKRVQDNFQLLKYMEQHHLKIGDELRLLEYDAFAGAYTIEKDGEQLQVTSAVASQIYIEK 5cvi A 2.80 BS03 ZN A 3 H76 E80 H95 D160 H74 E78 H93 D158 Q9KIJ2 PNKEDYLKIIYELSERDEKISNKQIAEKMSVSAPAVSEMVKKLLLEDLVLKDKQAGYLLTKKGQILASSLYRKHRLIEVFLMNHLNYTADEIHEEAEVLEHTVSDVFVERLDKFLNYPKVCPHGGTIPQHGQPLVERYRTTLKGVTEMGVYLLKRVQDNFQLLKYMEQHHLKIGDELRLLEYDAFAGAYTIEKDGEQLQVTSAVASQIYIEK 5cvi A 2.80 BS04 ZN A 4 E111 H132 E109 H130 Q9KIJ2 PNKEDYLKIIYELSERDEKISNKQIAEKMSVSAPAVSEMVKKLLLEDLVLKDKQAGYLLTKKGQILASSLYRKHRLIEVFLMNHLNYTADEIHEEAEVLEHTVSDVFVERLDKFLNYPKVCPHGGTIPQHGQPLVERYRTTLKGVTEMGVYLLKRVQDNFQLLKYMEQHHLKIGDELRLLEYDAFAGAYTIEKDGEQLQVTSAVASQIYIEK 5cvi A 2.80 BS05 ZN A 5 H172 E198 H170 E196 Q9KIJ2 PNKEDYLKIIYELSERDEKISNKQIAEKMSVSAPAVSEMVKKLLLEDLVLKDKQAGYLLTKKGQILASSLYRKHRLIEVFLMNHLNYTADEIHEEAEVLEHTVSDVFVERLDKFLNYPKVCPHGGTIPQHGQPLVERYRTTLKGVTEMGVYLLKRVQDNFQLLKYMEQHHLKIGDELRLLEYDAFAGAYTIEKDGEQLQVTSAVASQIYIEK 5cvi B 2.80 BS03 ZN B 3 H76 H95 D160 H76 H95 D160 Q9KIJ2 MTPNKEDYLKIIYELSERDEKISNKQIAEKMSVSAPAVSEMVKKLLLEDLVLKDKQAGYLLTKKGQILASSLYRKHRLIEVFLMNHLNYTADEIHEEAEVLEHTVSDVFVERLDKFLNYPKVCPHGGTIPQHGQPLVERYRTTLKGVTEMGVYLLKRVQDNFQLLKYMEQHHLKIGDELRLLEYDAFAGAYTIEKDGEQLQVTSAVASQIYIEKK 5cyv A 1.52 BS01 WCA B 1 V22 L23 V26 V37 R38 S41 M62 L64 V113 H117 V19 L20 V23 V34 R35 S38 M59 L61 V105 H109 Q0S6D0 SQALSDDIGFLLSRVGGMVLGAVNKALVPTGLRVRSYSVLVLACEQAEGVNQRGVAATMGLDPSQIVGLVDELEERGLVVRTLRNKLIAATEEGRRLRDDAKARVDAAHGRYFEGIPDTVVNQMRDTLQSIAFPTFVE 5cyv A 1.52 BS02 WCA B 2 F13 S16 R17 G20 L23 G24 N27 K28 V31 R36 F10 S13 R14 G17 L20 G21 N24 K25 V28 R33 Q0S6D0 SQALSDDIGFLLSRVGGMVLGAVNKALVPTGLRVRSYSVLVLACEQAEGVNQRGVAATMGLDPSQIVGLVDELEERGLVVRTLRNKLIAATEEGRRLRDDAKARVDAAHGRYFEGIPDTVVNQMRDTLQSIAFPTFVE 5cyv B 1.52 BS01 WCA B 1 D10 G12 F13 S16 G20 L23 R36 D7 G9 F10 S13 G17 L20 R33 Q0S6D0 SQALSDDIGFLLSRVGGMVLGAVNKALVPTGLRVRSYSVLVLACEQAEGVNQRGVAATMGLDPSQIVGLVDELEERGLVVRTLDPSDRRNKLIAATEEGRRLRDDAKARVDAAHGRYFEGIPDTVVNQMRDTLQSIAFPTFVE 5cyv B 1.52 BS02 WCA B 3 L23 V26 V37 R38 Y40 S41 M62 V113 H117 L20 V23 V34 R35 Y37 S38 M59 V110 H114 Q0S6D0 SQALSDDIGFLLSRVGGMVLGAVNKALVPTGLRVRSYSVLVLACEQAEGVNQRGVAATMGLDPSQIVGLVDELEERGLVVRTLDPSDRRNKLIAATEEGRRLRDDAKARVDAAHGRYFEGIPDTVVNQMRDTLQSIAFPTFVE 5czg A 1.45 BS01 BMF A 1 M30 V35 L40 Y85 N86 W92 M31 V36 L41 Y86 N87 W93 D0A3H5 GMSKNERDTSFNKNGCLVFVSRLWDLDKLGMFHHPVSAEELPDYHTVIKRPVDLSSIRDGIEKGTYATDVDVQNDVARMITNALEYNAKGSTWYQEAMSFRKTYLDLARQSGLVV 5d1j A 1.80 BS01 56H A 1 I10 E12 V18 A31 F80 E81 F82 L83 H84 Q85 D86 Q131 L134 A144 D145 I10 E12 V16 A29 F64 E65 F66 L67 H68 Q69 D70 Q115 L118 A128 D129 2.7.11.22 P24941 15027863 MENFQKVEKIGEYGVVYKARNKLTGEVVALKKIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL