2mnj B BS01 III A 1 F41 Y46 R49 F64 P66 S67 Y68 N69 F70 A71 L75 A93 I96 K97 I98 F99 H100 I101 R102 K103 E104 Y108 Y110 F18 Y23 R26 F41 P43 S44 Y45 N46 F47 A48 L52 A70 I73 K74 I75 F76 H77 I78 R79 K80 E81 Y85 Y87 26210662 PHEQQEDVPEYEVKMKRFKGAAYKLRILIENKAPNSKPDRFSPSYNFAENILYINGKLSIPLPRDIVVNAADIKIFHIRKERTLYIYI 3ja8 2 3.80 BS01 ADP 2 1 I505 G546 T547 A548 K549 S550 Q551 E608 L695 I293 G334 T335 A336 K337 S338 Q339 E396 L483 3.6.4.12 P29469 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 3ja8 2 3.80 BS02 ADP 5 1 V807 R808 V546 R547 3.6.4.12 P29469 PNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSSPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIY 3ja8 3 3.80 BS01 ADP 3 1 S370 I371 Y372 P411 S412 T413 A414 K415 S416 Q417 S317 I318 Y319 P358 S359 T360 A361 K362 S363 Q364 3.6.4.12 P24279 TFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 3ja8 3 3.80 BS02 ADP 7 1 E491 A699 R700 E703 E438 A566 R567 E570 3.6.4.12 P24279 TFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 3ja8 4 3.80 BS01 ADP 4 1 S529 I530 Y531 P570 S571 T572 S573 K574 S575 Q576 L724 S344 I345 Y346 P385 S386 T387 S388 K389 S390 Q391 L539 3.6.4.12 P30665 LRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDERDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYAT 3ja8 4 3.80 BS02 ADP 6 1 E650 R701 T795 R796 E465 R516 T597 R598 3.6.4.12 P30665 LRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDERDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYAT 3ja8 5 3.80 BS01 ADP 3 1 R549 I650 R651 R492 I590 R591 3.6.4.12 P29496 SFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNTGNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS 3ja8 5 3.80 BS02 ADP 5 1 S377 I378 F379 P418 G419 T420 A421 K422 S423 Q424 I568 I575 S320 I321 F322 P361 G362 T363 A364 K365 S366 Q367 I511 I518 3.6.4.12 P29496 SFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNTGNTVSLPRSCNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS 3ja8 6 3.80 BS01 ADP 6 1 A536 V537 F538 P577 S578 T579 S580 K581 S582 A312 V313 F314 P353 S354 T355 S356 K357 S358 3.6.4.12 P53091 VDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKGLRRVVRKYAPERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTRSLGVRDLTYKISFLACHVISIGSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDV 3ja8 7 3.80 BS01 ADP 7 1 I422 Y423 P462 G463 V464 A465 K466 S467 Q468 V616 I382 Y383 P422 G423 V424 A425 K426 S427 Q428 V576 3.6.4.12 P38132 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQ 3wz6 A 1.40 BS01 IXZ A 1 D33 D35 G37 Y79 G80 D81 F116 L125 I217 D219 G221 T222 Y226 I300 I304 D33 D35 G37 Y79 G80 D81 F116 L125 I217 D219 G221 T222 Y226 I300 I304 3.4.23.22 P11838 25630461 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 3wz7 A 1.90 BS01 IXY A 1 D33 D35 Y79 G80 D81 S83 S115 F116 I122 L125 F194 I217 D219 G221 T222 I300 I302 I304 D33 D35 Y79 G80 D81 S83 S115 F116 I122 L125 F194 I217 D219 G221 T222 I300 I302 I304 3.4.23.22 P11838 25630461 STGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYHAPGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCSATLPSFTFGVGSARIVIPGDYIDFGPISTGSSSCFGGIQSSAGIGINIFGDVALKAAFVVFNGATTPTLGFASK 4d47 A 2.77 BS01 FRU A 1 W45 D46 H97 W131 R202 D203 E287 Y352 W42 D43 H94 W128 R199 D200 E284 Y349 2.4.1.10 26208466 YNYKPTLWTRADALKVHEDDPTTTQPVIDIAFPVMSEEVFIWDTMPLRDFDGEIISVNGWCIIFTLTADRNTDNPQFQDENGNYDITRDWEDRHGRARICYWYSRTGKDWIFGGRVMAEGVSPTTREWAGTPILLNDRGDIDLYYTCVTPGATIAKVRGKIVTSDQSVSLEGFQQVTSLFSADGTIYQTEEQNAFWNFRDPSPFIDRNDGKLYMLFEGNVAGPRGSHEITQAEMGNVPPGYEDVGGAKYQAGCVGLAVAKDLSGSEWQILPPLITAVGVNDQTERPHFVFQDGKYYLFTISHKYTFADNLTGPDGVYGFVSDKLTGPYTPMNSSGLVLGNPSSQPFQTYSHYVMPNGLVTSFIDSVPWKGKDYRIGGTEAPTVKILLKGDRSFIVDSFDYGYIPAMKDITL 4d47 A 2.77 BS02 GLC A 1 R96 H97 H305 Y352 R93 H94 H302 Y349 2.4.1.10 26208466 YNYKPTLWTRADALKVHEDDPTTTQPVIDIAFPVMSEEVFIWDTMPLRDFDGEIISVNGWCIIFTLTADRNTDNPQFQDENGNYDITRDWEDRHGRARICYWYSRTGKDWIFGGRVMAEGVSPTTREWAGTPILLNDRGDIDLYYTCVTPGATIAKVRGKIVTSDQSVSLEGFQQVTSLFSADGTIYQTEEQNAFWNFRDPSPFIDRNDGKLYMLFEGNVAGPRGSHEITQAEMGNVPPGYEDVGGAKYQAGCVGLAVAKDLSGSEWQILPPLITAVGVNDQTERPHFVFQDGKYYLFTISHKYTFADNLTGPDGVYGFVSDKLTGPYTPMNSSGLVLGNPSSQPFQTYSHYVMPNGLVTSFIDSVPWKGKDYRIGGTEAPTVKILLKGDRSFIVDSFDYGYIPAMKDITL 4d47 B 2.77 BS01 FRU B 1 W45 D46 H97 W131 R202 D203 E287 W42 D43 H94 W128 R199 D200 E284 2.4.1.10 26208466 YNYKPTLWTRADALKVHEDDPTTTQPVIDIAFPVMSEEVFIWDTMPLRDFDGEIISVNGWCIIFTLTADRNTDNPQFQDENGNYDITRDWEDRHGRARICYWYSRTGKDWIFGGRVMAEGVSPTTREWAGTPILLNDRGDIDLYYTCVTPGATIAKVRGKIVTSDQSVSLEGFQQVTSLFSADGTIYQTEEQNAFWNFRDPSPFIDRNDGKLYMLFEGNVAGPRGSHEITQAEMGNVPPGYEDVGGAKYQAGCVGLAVAKDLSGSEWQILPPLITAVGVNDQTERPHFVFQDGKYYLFTISHKYTFADNLTGPDGVYGFVSDKLTGPYTPMNSSGLVLGNPSSQPFQTYSHYVMPNGLVTSFIDSVPWKGKDYRIGGTEAPTVKILLKGDRSFIVDSFDYGYIPAMKDITL 4d47 B 2.77 BS02 GLC B 1 R96 H97 H305 Y352 D367 R93 H94 H302 Y349 D364 2.4.1.10 26208466 YNYKPTLWTRADALKVHEDDPTTTQPVIDIAFPVMSEEVFIWDTMPLRDFDGEIISVNGWCIIFTLTADRNTDNPQFQDENGNYDITRDWEDRHGRARICYWYSRTGKDWIFGGRVMAEGVSPTTREWAGTPILLNDRGDIDLYYTCVTPGATIAKVRGKIVTSDQSVSLEGFQQVTSLFSADGTIYQTEEQNAFWNFRDPSPFIDRNDGKLYMLFEGNVAGPRGSHEITQAEMGNVPPGYEDVGGAKYQAGCVGLAVAKDLSGSEWQILPPLITAVGVNDQTERPHFVFQDGKYYLFTISHKYTFADNLTGPDGVYGFVSDKLTGPYTPMNSSGLVLGNPSSQPFQTYSHYVMPNGLVTSFIDSVPWKGKDYRIGGTEAPTVKILLKGDRSFIVDSFDYGYIPAMKDITL 4d47 E 2.77 BS01 FRU E 1 W45 D46 L69 H97 W131 R202 D203 E287 W42 D43 L66 H94 W128 R199 D200 E284 2.4.1.10 26208466 YNYKPTLWTRADALKVHEDDPTTTQPVIDIAFPVMSEEVFIWDTMPLRDFDGEIISVNGWCIIFTLTADRNTDNPQFQDENGNYDITRDWEDRHGRARICYWYSRTGKDWIFGGRVMAEGVSPTTREWAGTPILLNDRGDIDLYYTCVTPGATIAKVRGKIVTSDQSVSLEGFQQVTSLFSADGTIYQTEEQNAFWNFRDPSPFIDRNDGKLYMLFEGNVAGPRGSHEITQAEMGNVPPGYEDVGGAKYQAGCVGLAVAKDLSGSEWQILPPLITAVGVNDQTERPHFVFQDGKYYLFTISHKYTFADNLTGPDGVYGFVSDKLTGPYTPMNSSGLVLGNPSSQPFQTYSHYVMPNGLVTSFIDSVPWKGKDYRIGGTEAPTVKILLKGDRSFIVDSFDYGYIPAMKDITL 4qao A 2.10 BS01 HEM A 1 R13 C14 C17 H18 V28 G29 P30 L32 I35 S40 G41 Y46 Y48 T49 D50 I53 W59 M64 Y67 L68 K73 I75 A81 H82 G83 L94 R16 C17 C20 H21 V31 G32 P33 L35 I38 S43 G44 Y49 Y51 T52 D53 I56 W62 M67 Y70 L71 K76 I78 A84 H85 G86 L97 P00044 FKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIKKNVLWDENNMSEYLTNPAKYIPGCGMAHGGLKKEKDRNDLITYLKKASE 4qao B 2.10 BS01 HEM B 1 R13 C14 C17 H18 V28 G29 P30 L32 I35 S40 G41 Y46 Y48 T49 D50 I53 W59 M64 Y67 K73 I75 G83 L94 R16 C17 C20 H21 V31 G32 P33 L35 I38 S43 G44 Y49 Y51 T52 D53 I56 W62 M67 Y70 K76 I78 G86 L97 P00044 FKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIKKNVLWDENNMSEYLTNPAKYIPGCGMAHGGLKKEKDRNDLITYLKKASE 4qao C 2.10 BS01 HEM C 1 R13 C14 C17 H18 V28 G29 P30 I35 S40 G41 Y46 Y48 T49 D50 I53 W59 M64 Y67 K73 I75 A81 R16 C17 C20 H21 V31 G32 P33 I38 S43 G44 Y49 Y51 T52 D53 I56 W62 M67 Y70 K76 I78 A84 P00044 FKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIKKNVLWDENNMSEYLTNPAKYIPGCGMAHGGLKKEKDRNDLITYLKKASE 4qh6 A 3.13 BS01 33L A 1 Q19 G23 C25 W26 G65 G66 L67 M68 A138 D161 H162 Q19 G23 C25 W26 G65 G66 L67 M68 A138 D161 H162 3.4.22.51 P25779 26173110 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG 4r55 A 1.80 BS01 NUC B 1 K24 W26 A27 L28 G29 L35 Y44 R46 K22 W24 A25 L26 G27 L33 Y42 R44 Q97ZE3 25555709 SGKKPVKVKTPAGKEAELVPEKVWALGRVKIGLFKDPETGKYFRHKLPDDYPI 4r55 A 1.80 BS02 NUC C 1 V31 I33 R46 H47 K48 V29 I31 R44 H45 K46 Q97ZE3 25555709 SGKKPVKVKTPAGKEAELVPEKVWALGRVKIGLFKDPETGKYFRHKLPDDYPI 4r56 A 2.30 BS01 NUC C 1 K24 W26 A27 L28 A29 P30 K31 R33 L40 Y49 R51 K23 W25 A26 L27 A28 P29 K30 R32 L39 Y48 R50 Q97ZE3 25555709 SSGKKPVKVKTPAGKEAELVPEKVWALAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 4r56 A 2.30 BS02 NUC D 1 R33 V36 R51 H52 K53 R32 V35 R50 H51 K52 Q97ZE3 25555709 SSGKKPVKVKTPAGKEAELVPEKVWALAPKGRKGVKIGLFKDPETGKYFRHKLPDDYPI 4rdh A 2.10 BS01 AMP A 1 V36 G37 G39 G40 I60 D61 D63 R72 Q73 K85 F108 V109 I129 D130 S131 P134 V35 G36 G38 G39 I59 D60 D62 R71 Q72 K84 F107 V108 I128 D129 S130 P133 6.1.-.- Q46927 26101842 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4rdi C 1.95 BS01 ATP C 1 V36 G37 I38 G39 G40 I60 D61 D63 R72 Q73 K85 F108 V109 A128 I129 D130 S131 P134 V35 G36 I37 G38 G39 I59 D60 D62 R71 Q72 K84 F107 V108 A127 I128 D129 S130 P133 6.1.-.- Q46927 26101842 SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPGFGAATMVTATFGFVAVSHALKKMMAKAARQ 4ru9 A 2.65 BS01 NUC T 1 Q38 Y39 W42 G46 I47 I48 S62 W64 K86 A87 R93 K293 K311 R313 P316 K317 T318 I319 G320 C321 S322 K323 N324 P326 T329 R351 Q38 Y39 W42 G46 I47 I48 S62 W64 K86 A87 R93 K288 K306 R308 P311 K312 T313 I314 G315 C316 S317 K318 N319 P321 T324 R346 2.7.7.7 Q9Y253 25988947 MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 4ru9 A 2.65 BS02 NUC P 1 S113 D115 E116 K224 S257 L258 G259 G260 K261 L262 L381 R382 R383 C384 S113 D115 E116 K219 S252 L253 G254 G255 K256 L257 L376 R377 R378 C379 2.7.7.7 Q9Y253 25988947 MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSAS 4rua A 3.07 BS01 NUC T 1 V32 S34 F37 S40 G41 A42 P60 V62 G218 E219 A220 R242 K243 S244 I245 G246 R247 I248 T250 R331 R332 R336 V32 S34 F37 S40 G41 A42 P60 V62 G218 E219 A220 R242 K243 S244 I245 G246 R247 I248 T250 R331 R332 R336 2.7.7.7 Q97W02 25988947 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI 4rua A 3.07 BS03 DTP A 1 D7 F8 D9 Y10 F11 Y12 A44 T45 Y48 R51 A57 D105 E106 K159 D7 F8 D9 Y10 F11 Y12 A44 T45 Y48 R51 A57 D105 E106 K159 2.7.7.7 Q97W02 25988947 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI 4ruc A 2.90 BS01 NUC T 1 V32 S34 F37 S40 G41 A42 G58 P60 G218 E219 A220 R242 K243 S244 I245 G246 R247 I248 T250 K275 L293 R331 R332 R336 V32 S34 F37 S40 G41 A42 G58 P60 G218 E219 A220 R242 K243 S244 I245 G246 R247 I248 T250 K275 L293 R331 R332 R336 2.7.7.7 Q97W02 25988947 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI 4ruc A 2.90 BS02 NUC P 1 S103 D105 E106 K152 G185 I186 G187 N188 I189 T190 V296 S297 R298 G299 R300 T301 S103 D105 E106 K152 G185 I186 G187 N188 I189 T190 V296 S297 R298 G299 R300 T301 2.7.7.7 Q97W02 25988947 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI 4ruc A 2.90 BS03 DTP A 1 D7 F8 Y10 F11 Y12 A44 T45 Y48 R51 D105 K159 D7 F8 Y10 F11 Y12 A44 T45 Y48 R51 D105 K159 2.7.7.7 Q97W02 25988947 MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVFAKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGINKLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVTMKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI 4rzy A 1.95 BS01 FE A 1 D295 D297 D307 E421 D287 D289 D299 E413 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy A 1.95 BS02 FE A 2 D307 H371 C404 E406 E421 D299 H363 C396 E398 E413 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy A 1.95 BS03 MES A 1 T265 L267 D297 Y366 C368 D377 L381 T257 L259 D289 Y358 C360 D369 L373 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy A 1.95 BS04 MES C 1 W95 Y117 F142 W87 Y109 F134 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy C 1.95 BS01 MES A 1 W95 Y117 D143 W87 Y109 D135 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy C 1.95 BS04 MES C 1 T265 L267 D297 Y366 C368 D377 T257 L259 D289 Y358 C360 D369 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy D 1.95 BS01 MES B 1 W95 Y117 F142 D143 W87 Y109 F134 D135 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzy D 1.95 BS04 MES D 1 T265 L267 D297 D307 Y366 C368 D377 L381 T257 L259 D289 D299 Y358 C360 D369 L373 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzz A 2.10 BS01 FE A 1 D307 H371 E406 E421 D299 H363 E398 E413 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzz A 2.10 BS03 PO4 A 1 D295 D297 D307 Y366 H371 D377 E406 D287 D289 D299 Y358 H363 D369 E398 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4rzz D 2.10 BS03 PO4 D 1 D297 D307 Y366 H371 D377 E406 D289 D299 Y358 H363 D369 E398 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4s00 A 2.10 BS03 AKR A 1 T265 L267 D297 D377 T257 L259 D289 D369 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKAGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4s00 A 2.10 BS04 AKR C 1 M92 W95 M84 W87 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKAGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4s00 C 2.10 BS04 AKR C 1 L267 D297 D377 L259 D289 D369 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKAGCLMHGVGLCDEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4s01 A 2.10 BS01 FE A 1 D295 D307 H371 E406 E421 D287 D299 H363 E398 E413 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCNEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4s01 A 2.10 BS03 AKR A 1 L267 D297 Y366 N377 L259 D289 Y358 N369 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCNEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4s01 B 2.10 BS03 AKR B 1 L267 D297 D307 Y366 N377 L259 D289 D299 Y358 N369 D0CY07 26154071 RKIDPSRGATLGDGTPNDNDRIEIGPTQLAFSEWAAAGLQLPNLDRMREYRWKRLTQAIVDRGYGGLLMFDPLNIRYATDSTNMQLWNTHNPFRAVLLCADGYMVIWDYKNSPFLSKFNPLVREQRSGADLFYFDRGDKVDVQADVFANEVRVLMQDHAPGHTRLAVDKIMLHGLRALEAQGFEIMEGEEVTEKTRAIKGPDEILAMRCASHACETAVAEMEKFARAHVGDGKTSEDDIWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRITQKNEIIAFDTDLIGSYGICVDISRTWWIGDQKPRPDMVYAMQHAHEHIMTNMEMLKPGVMIPDLTANCHRLDDKFQAQKYGCLMHGVGLCNEWPLVAYPDKAVPGSYDYPLEPGMVLCVEAAVGEVGGDFSIKLEDQVLITEDGYENLTTYPFDAALMGLA 4tvd A 2.30 BS02 BGC A 1 A2249 G2250 E2265 S2266 N2267 E2270 D2294 A455 G456 E471 S472 N473 E476 D500 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS04 BGC A 2 D2034 R2036 H2096 G2097 T2098 D240 R242 H302 G303 T304 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS05 BGC A 3 E1895 S1896 G1897 E1973 Y1974 Y2128 E102 S103 G104 E180 Y181 Y334 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS06 BGC A 4 L2167 R2208 D2210 E2248 H2321 D2322 F2641 D2643 Y2650 Q2694 L373 R414 D416 E454 H527 D528 F847 D849 Y856 Q900 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS07 BGC A 5 N2241 N2588 N2683 M2684 Q2685 N447 N794 N889 M890 Q891 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS08 BGC A 6 D2002 H2003 W2014 M2035 T2098 D2099 Q2102 D208 H209 W220 M241 T304 D305 Q308 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS09 BGC A 7 Y1793 D1795 Q1805 F1806 K2046 L2070 S2072 D2073 Q2074 Y12 D14 Q24 F25 K252 L276 S278 D279 Q280 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS10 BGC A 8 N2161 A2162 N2217 Y2762 Y2764 K2765 N367 A368 N423 Y968 Y970 K971 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4tvd A 2.30 BS11 BGC A 9 Q2677 A2678 H2681 Q883 A884 H887 2.4.1.5 Q8G9Q2 GLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVTEGHYGTWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDDKLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNGALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDSTNAFSTKNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLITVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIERRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGGYLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNMLQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGADWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKSVRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHKNQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIRGVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNLIYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDHTFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKYAGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKLD 4u1q A 2.09 BS01 3DJ A 1 Y99 Y134 F147 M151 W154 H245 V248 A277 Y288 D292 Y295 F296 H335 Y96 Y131 F144 M148 W151 H242 V245 A274 Y285 D289 Y292 F293 H332 C0LTM6 ELSALVPVLFGHAAFQQLNAGCQLGLFELLHERGPLSAEEVADALRLPRRSADILLLGTTALGLSTVTDGGYRNGAPIGAAFRDGLWPVLRDIVQYQDKIAYQPAADYVESLRTGQNAGIRHFPGTTRDLYSRLAAVPGLEELFYRGMHAWSQLSNPVLLAQPDFTRVHRVLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFTDSYPAGHDCVLFAHQLVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDDDRTGPLYAALDNVYFTTLPFRHSTIHRWADCESWLREAGFTDVGRTAPPGWTPHGVVSGSRPR 4u1q A 2.09 BS02 SAH A 1 Y134 Y148 M151 S155 G178 G179 G180 V183 N184 D201 R202 A227 D228 I229 A244 H245 Q246 I249 W250 Y131 Y145 M148 S152 G175 G176 G177 V180 N181 D198 R199 A224 D225 I226 A241 H242 Q243 I246 W247 C0LTM6 ELSALVPVLFGHAAFQQLNAGCQLGLFELLHERGPLSAEEVADALRLPRRSADILLLGTTALGLSTVTDGGYRNGAPIGAAFRDGLWPVLRDIVQYQDKIAYQPAADYVESLRTGQNAGIRHFPGTTRDLYSRLAAVPGLEELFYRGMHAWSQLSNPVLLAQPDFTRVHRVLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFTDSYPAGHDCVLFAHQLVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDDDRTGPLYAALDNVYFTTLPFRHSTIHRWADCESWLREAGFTDVGRTAPPGWTPHGVVSGSRPR 4u49 B 1.80 BS01 CA B 1 D194 I195 N216 T217 G220 P221 D165 I166 N187 T188 G191 P192 Q47465 DDTMLMLLKKDNATYLSWSTDAGNVVRQDVYRSTSSAQAGSEKIAELNSSDRTFTDLTANPQSDYWYWVDTVSGNNSVLKSNAASTAPAAASPECKAGAVIKDKTVDCGGITLGLSCSGDSDKQPPVITLENATIKNLRISEKGGSDGIHCKSGNCRIENVIWEDICEDAATNLGKTMTIVGGVAHNTTNGPGGKPDKVLQQNAKNSHTIVQGNFTLTGQHGKLWRSCGDCTNNGGPRNLTIISATVNGTIDSIAGVNRNFGDVAEIRDLRIKGYKEGKPPVCEEFNGVEKGKGKSDKYGEFWDTKNCKVSRSNVKPL 4u60 A 1.50 BS01 SIA A 1 T73 V74 A75 Q80 K82 P83 T84 T41 V42 A43 Q48 K50 P51 T52 E2ESL7 IEVLNLVTGPDSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLNEDLTCNTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVRN 4u60 B 1.50 BS01 SIA B 1 T73 V74 A75 Q80 K82 T84 T39 V40 A41 Q46 K48 T50 E2ESL7 IEVLNLVTGSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVRN 4u60 D 1.50 BS01 SIA D 1 T73 V74 A75 N76 Q80 K82 T84 T41 V42 A43 N44 Q48 K50 T52 E2ESL7 IEVLNLVTGPDSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLNEDNTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVRN 4u61 C 1.65 BS01 SIA C 1 T73 V74 A75 Q80 D81 K82 T40 V41 A42 Q47 D48 K49 E2ESL7 EVLNLVTGPDSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLNEDLTCNTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVRN 4u61 E 1.65 BS01 SIA E 1 T73 V74 A75 K82 P83 T84 T42 V43 A44 K51 P52 T53 E2ESL7 NIEVLNLVTGPDSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLNEDLTCNTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVRN 4u61 H 1.65 BS01 SIA H 1 T73 V74 A75 Q80 D81 K82 T84 T41 V42 A43 Q48 D49 K50 T52 E2ESL7 IEVLNLVTGPDSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLNTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVR 4u62 A 1.55 BS01 SIA B 1 H132 R137 H101 R106 E2ESL7 NIEVLNLVTGPDSITTIELYLNTRMGQNDESKDNYGYSEKVTVANSSDQDKPTSGEIPTYSTARINLPMLNEDLTCNTLTMWEAVSVKTEVVGVSSLVNVHMATKRMYDDKGIGFPVEGMNFHMFAVGGEPLELQFLTGNYRTDYSANDKLVVPPIKHQSTQGLNPHYKQKLTKDGAFPVECWCPDPSKNENTRYYGSYTGGQSTPPVLQFTNTVTTVLLDENGVGPLCKGDGLYVSCCDIVGFLVGKDGDMQYRGLPRYFNILLRKRTVRN 4u67 L 3.65 BS01 NUC Y 1 K16 R28 Y32 S34 S35 H37 Y39 Q41 G48 Q49 T50 A53 K64 T65 Y94 K95 H97 G98 R99 K9 R21 Y25 S27 S28 H30 Y32 Q34 G41 Q42 T43 A46 K57 T58 Y87 K88 H90 G91 R92 Q9RSL2 RRKLRTRRKVRTTTAASGRLRLSVYRSSKHIYAQIIDDSRGQTLAAASSAALKSGNKTDTAAAVGKALAAAAAEKGIKQVVFDRGSYKYHGRVKALADAAREGG 4u67 S 3.65 BS01 NUC Y 1 R8 V22 Y24 N25 N29 S31 K67 R74 H80 D82 Y84 R8 V22 Y24 N25 N29 S31 K67 R74 H80 D82 Y84 Q9RX88 MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR 4u67 T 3.65 BS01 NUC Y 1 K72 A76 K61 A65 Q9RY65 NGRDSNPKYLGVKKFGGEVVKAGNILVRQRGTKFKAGQGVGMGRDHTLFALSDGKVVFINKGKGARFISIEAAQ 4u68 A 1.80 BS01 III D 1 E23 Y24 V25 V26 W45 F48 N52 E56 N60 N63 C64 K66 L67 E1 Y2 V3 V4 W23 F26 N30 E34 N38 N41 C42 K44 L45 Q7JXA8 EYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAAAKS 4uaj A 2.70 BS01 FAD A 1 Y167 R210 A211 Y212 S213 N227 V228 R229 A231 T232 P233 P234 V240 P241 G243 Q244 M245 S246 F406 Y39 R82 A83 Y84 S85 N99 V100 R101 A103 T104 P105 P106 V112 P113 G115 Q116 M117 S118 F278 1.6.5.- A5F5Y4 25471880 GVKKWECTVISNDNKATFIKELKLAIPDGESVPFRAGGYIQIEAPAHHVKYADFDVPEKYRGDWDKFNLFRYESKVDEPIIRAYSMANYPEEFGIIMLNVRIATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAAENDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEYYMCGPPMMNAAVINMLKNLGVEEENILLDDFGG 4uf1 A 2.30 BS01 III B 1 I49 Y53 D56 F57 S59 M60 Q63 I64 K77 I78 E80 A81 I84 R87 S89 V90 L92 A93 T94 F97 F135 I47 Y51 D54 F55 S57 M58 Q61 I62 K75 I76 E78 A79 I82 R85 S87 V88 L90 A91 T92 F95 F133 AAIEFDEIVKKLLNIYINDICTTGEKRLLNNYEKSILDRIYKSCEYIKKNYELDFNSMYNQININNITTSDIKSKIIEALLIDSRPSVKLATLSFISLIAEKWGEKNRAKIMEILSNEIVEKISNNGKDFIDFID 4uf2 A 3.00 BS01 III B 1 I49 Y53 D56 F57 M60 Q63 I64 K77 E80 A81 I84 D85 R87 S89 A93 I47 Y51 D54 F55 M58 Q61 I62 K75 E78 A79 I82 D83 R85 S87 A91 AAIEFDEIVKKLLNIYINDICTTGEKRLLNNYEKSILDRIYKSCEYIKKNYELDFNSMYNQININDITTSDIKSKIIEALLIDSRPSVKLATLSFISLIAEKWGEKNRAKIMEILSNEIVEKISNNGKDFIDFIDR 4uf3 A 2.70 BS01 III B 1 Y48 Y53 F57 M60 Q63 K77 E80 A81 I84 D85 R87 S89 L92 A93 T94 F135 I136 Y46 Y51 F55 M58 Q61 K75 E78 A79 I82 D83 R85 S87 L90 A91 T92 F133 I134 AAIEFDEIVKKLLNIYINDICTTGEKRLLNNYEKSILDRIYKSCEYIKKNYELDFNSMYNQININDITTSDIKSKIIEALLIDSRPSVKLATLSFISLIAEKWGEKNRAKIMEILSNEIVEKISNNGKDFIDFIDR 4utd A 2.36 BS01 ACP A 1 L139 G140 G142 K143 F144 A160 K162 L194 E211 A213 T217 E260 N261 L263 D274 L12 G13 G15 K16 F17 A33 K35 L67 E84 A86 T90 E133 N134 L136 D147 2.7.11.1 WALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNC 4uth A 1.25 BS01 FMN A 1 P22 P23 M24 C25 A57 Q99 H178 H181 R231 A301 W302 G303 G325 R326 L329 P21 P22 M23 C24 A56 Q98 H177 H180 R230 A300 W301 G302 G324 R325 L328 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLE 4uti A 1.10 BS02 COU A 1 C25 Y27 I66 H178 H181 F183 C24 Y26 I65 H177 H180 F182 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLE 4utj A 1.07 BS02 8CM A 1 C25 Y27 I66 H178 H181 F183 F269 C24 Y26 I65 H177 H180 F182 F268 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLER 4utl A 1.23 BS02 COU A 1 Y27 I66 H178 H181 F183 W302 Y26 I65 H177 H180 F182 W301 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLE 4utl A 1.23 BS03 COU A 2 W278 W302 R326 W277 W301 R325 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLE 4utl A 1.23 BS04 COU A 3 H181 F183 F269 H180 F182 F268 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLE 4utm A 1.09 BS02 8CM A 1 Y27 I66 H178 H181 F183 Y26 I65 H177 H180 F182 1.6.99.1 SALFEPYTLKDVTLRNRIAIPPMCQYMAEDGMINDWHHVHLAGLARGGAGLLVVEATAVAPEGRITPGCAGIWSDAHAQAFVPVVQAIKAAGSVPGIQIAHAGRKASANRPWEGDDHIAADDTRGWETIAPSAIAFGAHLPKVPREMTLDDIARVKQDFVDAARRARDAGFEWIELHFAHGFLGQSFFSEHSNKRTDAYGGSFDNRSRFLLETLAAVREVWPENLPLTARFGVLEYDGRDEQTLEESIELARRFKAGGLDLLSVSVGFTIPDTNIPWGPAFMGPIAERVRREAKLPVTSAWGFGTPQLAEAALQANQLDLVSVGRAHLADPHWAYFAAKELGVEKASWTLPAPYAHWLER 4wyy A 1.28 BS01 3VT A 1 G89 S90 Q146 Y177 N179 Y249 T343 G344 S345 T346 N373 G61 S62 Q118 Y149 N151 Y221 T315 G316 S317 T318 N345 3.5.2.6 P24735 APADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLE 4wz4 A 1.05 BS01 3VU A 1 S90 K93 Q146 Y177 N179 Y249 T343 G344 S345 N373 S62 K65 Q118 Y149 N151 Y221 T315 G316 S317 N345 3.5.2.6 P24735 APADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLE 4wz5 A 1.60 BS01 3VU A 1 A66 S67 K70 M99 W102 S115 V117 L155 G207 F208 S209 R250 A46 S47 K50 M79 W82 S95 V97 L135 G187 F188 S189 R230 3.5.2.6 P14489 SITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASKEYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSASKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGII 4xac A 1.87 BS01 AKG A 1 I116 T126 H129 D131 W147 H209 H215 A217 R226 I110 T120 H123 D125 W141 H203 H209 A211 R220 MEVVGTIDHRDREEFRSRGFAILPQVASESEVAWLRQAYDRLFVRRATPGAEDFYDIAGQRGPPLLPQIIKPEKYVPELLDSPHFARCRSIASAFLDMAEEELEFYGHAILKPPRYGAPTPWHQDEAYMDPRWRRRGLSIWTTLDEATVESGCLHYLPGGHRGPVLPHHHIDNDDRIRGLMTDDVDPTSAVACPLAPGGAVVHDFRTPHYAGPNLTDQPRRAYVLVFMSAPAEVADPEPRPWMDW 4xca A 2.30 BS01 AKG A 1 Y89 L91 L99 H102 L139 Y141 H206 T208 R217 L219 Y88 L90 L98 H101 L138 Y140 H205 T207 R216 L218 Q2MFS1 PALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xca B 2.30 BS01 AKG B 1 Y89 L91 L99 H102 K137 Y141 H206 T208 R217 L219 Y78 L80 L88 H91 K126 Y130 H191 T193 R202 L204 Q2MFS1 ALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERANTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xca C 2.30 BS01 AKG C 1 Y89 L91 L99 K137 Y141 H206 T208 R217 L219 Y87 L89 L97 K133 Y137 H202 T204 R213 L215 Q2MFS1 ALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xca D 2.30 BS01 AKG D 1 Y89 L91 L99 H102 Y141 H206 T208 R217 Y87 L89 L97 H100 Y138 H203 T205 R214 Q2MFS1 ALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xcb A 1.60 BS02 HY0 A 1 F46 R51 E87 Y89 L99 H102 K137 E202 W232 E234 D249 V252 E254 F49 R54 E90 Y92 L102 H105 K140 E205 W235 E237 D252 V255 E257 Q2MFS1 LHMVPALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xcb B 1.60 BS01 AKG B 1 Y89 L91 L99 H102 K137 L139 Y141 F153 H206 T208 R217 L219 Y92 L94 L102 H105 K139 L141 Y143 F155 H208 T210 R219 L221 Q2MFS1 LHMVPALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xcb B 1.60 BS02 HY0 B 1 F46 R51 E87 Y89 L99 H102 K137 E202 W232 E234 Y247 D249 E254 F49 R54 E90 Y92 L102 H105 K139 E204 W234 E236 Y249 D251 E256 Q2MFS1 LHMVPALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4xi9 A 3.10 BS01 III E 1 H496 H498 H499 N557 P559 T633 K634 Q839 F868 V895 H185 H187 H188 N246 P248 T322 K323 Q509 F538 V565 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xi9 D 3.10 BS01 III H 1 H496 H499 N557 P559 T633 K634 V895 H185 H188 N246 P248 T322 K323 V565 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xif A 3.20 BS01 III E 1 H496 H498 H499 N557 P559 Y632 T633 K634 Q839 F868 V895 P897 H185 H187 H188 N246 P248 Y321 T322 K323 Q513 F542 V569 P571 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xif A 3.20 BS02 12V A 1 H498 P559 T560 L563 L653 G654 P656 Q839 K842 V895 A896 K898 H901 R904 C917 H920 T921 T922 D925 H187 P248 T249 L252 L342 G343 P345 Q513 K516 V569 A570 K572 H575 R578 C591 H594 T595 T596 D599 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xif B 3.20 BS02 12V B 1 H498 P559 T560 L653 G654 P656 Q839 Y841 K842 L866 V895 A896 K898 H901 R904 C917 H920 T921 T922 D925 H187 P248 T249 L342 G343 P345 Q513 Y515 K516 L540 V569 A570 K572 H575 R578 C591 H594 T595 T596 D599 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xif D 3.20 BS01 III H 1 H498 H499 N557 P559 Y632 T633 K634 Q839 V895 P897 H187 H188 N246 P248 Y321 T322 K323 Q513 V569 P571 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xif D 3.20 BS02 12V D 1 H498 P559 T560 L653 G654 P656 F694 Q839 K842 L866 V895 A896 K898 H901 R904 C917 H920 T921 T922 D925 H187 P248 T249 L342 G343 P345 F383 Q513 K516 L540 V569 A570 K572 H575 R578 C591 H594 T595 T596 D599 2.4.1.255 O15294 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4xkj A 3.15 BS01 NAD A 1 Y101 V106 G152 G154 R155 I156 D175 I176 R179 H204 V205 P206 T211 A232 S233 R234 D258 H295 G297 F298 Y101 V106 G152 G154 R155 I156 D175 I176 R179 H204 V205 P206 T211 A232 S233 R234 D258 H295 G297 F298 MKIIMFSVRDDEEAAIREWEKKTGVQVDINRLELDAETAQLTKGYDGIVIQQRSHISNPAVYETLQKNGLRQLTSRTAGYDMIDLEQASERGLVVTNVPAYSPNSVAELALTQTMRLIRNLPLFDARGAEQDFRWAGLMAREIRSLTVGIIGAGRIGGTVARLFKALGATVIANDIVERVELKDIVTYVSKEELLQAADVVTLHVPLMDSTTQLIDADALALMKNDAVLINASRGPVVDTDALIAALQNKQIAGAALDTLNGEEHFFNQDLCGKELPSEQLKVLRTLPNVLITPHIGFYTNKAVQNMVEISLNDVLAILKTGTSEHQLNKVA 4xkj B 3.15 BS01 NAD B 1 Y101 V106 G152 A153 G154 R155 I156 N174 D175 I176 H204 V205 P206 S210 T211 A232 S233 R234 D258 H295 F298 Y101 V106 G152 A153 G154 R155 I156 N174 D175 I176 H204 V205 P206 S210 T211 A232 S233 R234 D258 H295 F298 MKIIMFSVRDDEEAAIREWEKKTGVQVDINRLELDAETAQLTKGYDGIVIQQRSHISNPAVYETLQKNGLRQLTSRTAGYDMIDLEQASERGLVVTNVPAYSPNSVAELALTQTMRLIRNLPLFDARGAEQDFRWAGLMAREIRSLTVGIIGAGRIGGTVARLFKALGATVIANDIVERVELKDIVTYVSKEELLQAADVVTLHVPLMDSTTQLIDADALALMKNDAVLINASRGPVVDTDALIAALQNKQIAGAALDTLNGEEHFFNQDLCGKELPSEQLKVLRTLPNVLITPHIGFYTNKAVQNMVEISLNDVLAILKTGTSEHQLNKVA 4xx5 A 2.76 BS01 43R A 1 W812 I831 K833 Y867 I879 E880 I881 V882 A885 M953 I963 D964 W576 I595 K597 Y631 I643 E644 I645 V646 A649 M717 I727 D728 2.7.1.153,2.7.11.1 P48736 SEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCRLLYYVNLLLIDHRFLLRRGEYVLHMWQISGFNADKLTSATNPDKENSMSISILLDNHPIARAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVL 4y14 A 1.90 BS01 C0A A 1 Y46 D48 V49 D181 F182 C215 S216 A217 G218 I219 G220 R221 Q262 Y45 D47 V48 D180 F181 C214 S215 A216 G217 I218 G219 R220 Q257 3.1.3.48 P18031 26214522 EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED 4y7l A 1.51 BS01 ZN A 1 H978 E1085 H106 E213 26200339 TPAAESLNARWRTAVVDGWNNAFSGRYPFKNVSSDASLPLLAKYLNTDTGRIARFLQNNLSGVLHREGSRWVPDTGLTFNPAFLKAINTLSEIADVAFTTGNAGLHFELRPGTAAGVMQTTLITDNQKLIYVNQMPVWKRFTWPADTEAPGASLSWVSTQAGTRQYADLPGSWGLIRLLEMARRKAAPGVASGWSLSWQAQDGRMLNYTLRTEAGEGPLVLLKLRNFVLPETVFE 4y7o A 2.24 BS01 ZN A 1 G930 H933 D942 G62 H65 D74 26200339 TPAAESLNARWRTAVVDGWNNAFSGRYPFKNVSSDASLPLLAKYLNTDTGRIARFLQNNLSGVLHREGSRWVPDTINTRGLTFNPAFLKAINTLSEIADVAFTTGNAGLHFELRPGTAAGVMQTTLITDNQKLIYVNQMPVWKRFTWPADTEAPGASLSWVSTQAGTRQYADLPGSWGLIRLLEMARRKAAPGVASGWSLSWQAQDGRMLNYTLRTEAGEGPLVLLKLRNFVLPETVFE 4y7o B 2.24 BS01 ZN B 1 E964 E1088 E96 E220 26200339 TPAAESLNARWRTAVVDGWNNAFSGRYPFKNVSSDASLPLLAKYLNTDTGRIARFLQNNLSGVLHREGSRWVPDTINTRGLTFNPAFLKAINTLSEIADVAFTTGNAGLHFELRPGTAAGVMQTTLITDNQKLIYVNQMPVWKRFTWPADTEAPGASLSWVSTQAGTRQYADLPGSWGLIRLLEMARRKAAPGVASGWSLSWQAQDGRMLNYTLRTEAGEGPLVLLKLRNFVLPETVFE 4ycx A 2.10 BS01 NUC T 1 L177 H365 Q366 H367 A384 R387 K438 R442 R445 R446 R449 K450 L456 N457 L41 H229 Q230 H231 A233 R236 K275 R279 R282 R283 R286 K287 L293 N294 2.7.7.7 Q9NP87 WMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSAFERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4ycx A 2.10 BS02 NUC P 1 F244 G245 V246 G247 T250 Q275 Q366 R387 F389 R416 D418 W434 F108 G109 V110 G111 T114 Q139 Q230 R236 F238 R253 D255 W271 2.7.7.7 Q9NP87 WMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSAFERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4ycx A 2.10 BS03 NUC D 1 G174 R175 T178 F179 H204 G206 E207 H208 S209 G38 R39 T42 F43 H68 G70 E71 H72 S73 2.7.7.7 Q9NP87 WMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSAFERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4yd1 A 1.75 BS01 NUC T 1 L177 H365 Q366 H367 C369 D383 A384 K438 R442 R445 R446 R449 K450 L456 N457 L40 H228 Q229 H230 C232 D235 A236 K278 R282 R285 R286 R289 K290 L296 N297 2.7.7.7 Q9NP87 MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCHMDAFERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4yd1 A 1.75 BS02 NUC P 1 G245 V246 G247 K249 T250 Q275 D332 Q366 R387 F389 R416 D418 W434 G108 V109 G110 K112 T113 Q138 D195 Q229 R239 F241 R256 D258 W274 2.7.7.7 Q9NP87 MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCHMDAFERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4yd2 A 2.47 BS01 NUC T 1 L177 K438 R442 R445 R446 R449 L456 N457 L40 K267 R271 R274 R275 R278 L285 N286 2.7.7.7 Q9NP87 MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4yd2 A 2.47 BS02 NUC P 1 F244 G245 V246 G247 T250 Q275 R323 D330 D332 F389 R416 D418 G433 W434 T435 G436 K438 F107 G108 V109 G110 T113 Q138 R186 D193 D195 F230 R245 D247 G262 W263 T264 G265 K267 2.7.7.7 Q9NP87 MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHERSFCIFRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA 4ylh A 2.58 BS01 YE1 A 1 D184 R185 L186 A188 E189 H222 Y225 A233 G234 I235 N236 L237 K238 F250 L251 R254 F292 I294 G295 G296 Q299 Y314 P318 I324 I325 G327 Q416 F432 D173 R174 L175 A177 E178 H211 Y214 A222 G223 I224 N225 L226 K227 F239 L240 R243 F281 I283 G284 G285 Q288 Y303 P307 I313 I314 G316 Q405 F421 Q8KLK7 DGLWAALTEAAASVEKLLATLPEHGARSSAERAEIAAAHDAARALRVRFLDTHADAVYDRLTDHRRVHLRLAELVEAAATAFPGLVPTQQQLAVERSLPQAAKEGHEIDQGIFLRAVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGEVEMEAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGAANLRLGRFAGPRVSRQVILEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTRLDGDAVLANRRMLNLADESPDGFRAYMAEFALMQALRLYGHDVIDKVGRF 4ylh B 2.58 BS01 YE1 B 1 R185 L186 A188 E189 H222 Y225 A233 G234 I235 N236 L237 K238 F250 L251 R254 F292 I294 G295 G296 Q299 I324 I325 G327 Q416 F432 R175 L176 A178 E179 H212 Y215 A223 G224 I225 N226 L227 K228 F240 L241 R244 F282 I284 G285 G286 Q289 I314 I315 G317 Q406 F422 Q8KLK7 TDGLWAALTEAAASVEKLLATLPEHGARSSAERAEIAAAHDAARALRVRFLDTHADAVYDRLTDHRRVHLRLAELVEAAATAFPGLVPTQQQLAVERSLPQAAKEGHEIDQGIFLRAVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGEVEMEAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGAANLRLGRFAGPRVSRQVILEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTRLDGDAVLANRRMLNLADESPDGFRAYMAEFALMQALRLYGHDVIDKVGRF 4ylh H 2.58 BS01 YE1 H 1 L186 A188 E189 H222 R224 Y225 A233 I235 N236 L237 K238 F250 L251 R254 I294 G295 G296 Q299 P318 I324 I325 P326 G327 F412 Q416 F432 L176 A178 E179 H212 R214 Y215 A223 I225 N226 L227 K228 F240 L241 R244 I284 G285 G286 Q289 P308 I314 I315 P316 G317 F402 Q406 F422 Q8KLK7 TDGLWAALTEAAASVEKLLATLPEHGARSSAERAEIAAAHDAARALRVRFLDTHADAVYDRLTDHRRVHLRLAELVEAAATAFPGLVPTQQQLAVERSLPQAAKEGHEIDQGIFLRAVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGEVEMEAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGAANLRLGRFAGPRVSRQVILEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTRLDGDAVLANRRMLNLADESPDGFRAYMAEFALMQALRLYGHDVIDKVGRF 4ylh K 2.58 BS01 YE1 K 1 R185 L186 E189 H222 R224 Y225 A233 G234 I235 N236 L237 K238 F250 R254 I294 G295 G296 Q299 I324 I325 G327 Q416 F432 R175 L176 E179 H212 R214 Y215 A223 G224 I225 N226 L227 K228 F240 R244 I284 G285 G286 Q289 I314 I315 G317 Q406 F422 Q8KLK7 TDGLWAALTEAAASVEKLLATLPEHGARSSAERAEIAAAHDAARALRVRFLDTHADAVYDRLTDHRRVHLRLAELVEAAATAFPGLVPTQQQLAVERSLPQAAKEGHEIDQGIFLRAVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGEVEMEAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGAANLRLGRFAGPRVSRQVILEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTRLDGDAVLANRRMLNLADESPDGFRAYMAEFALMQALRLYGHDVIDKVGRF 4yma B 1.90 BS01 4E5 B 1 Y61 P89 L90 T91 R96 L138 S142 T143 E193 Y58 P86 L87 T88 R93 L135 S139 T140 E190 P19491 26200741 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGS 4ymb A 1.93 BS01 4E7 A 1 E13 Y61 P88 L89 T90 R95 V137 G140 T142 M189 E190 S193 Y216 E10 Y58 P85 L86 T87 R92 V134 G137 T139 M186 E187 S190 Y213 P22756 26200741 RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGCP 4yo9 A 2.30 BS01 ZN A 1 L27 H41 C148 L27 H41 C148 3.4.22.- P0C6W3 26190463 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDMLAHRTGVSVEQMLAAIQSLHAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQ 4yog A 2.00 BS01 4F5 A 1 M25 H41 A46 L49 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 M25 H41 A46 L49 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 3.4.22.- P0C6W3 26190463 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDMLAHRTGVSVEQMLAAIQSLHAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQ 4yoi A 1.82 BS01 4F4 A 1 S24 M25 H41 C44 A46 L49 Y54 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 S24 M25 H41 C44 A46 L49 Y54 F143 L144 C145 C148 H166 M168 E169 D190 K191 Q192 3.4.22.- P0C6W3 26190463 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDMLAHRTGVSVEQMLAAIQSLHAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQ 4ysx A 2.25 BS01 FAD A 1 G48 A49 G50 G51 A52 T71 K72 M73 S78 H79 T80 A82 A83 Q84 G85 G86 Y199 A201 A235 T236 G237 T247 D255 L286 H387 Y388 G420 E421 R432 A435 S437 L438 G19 A20 G21 G22 A23 T42 K43 M44 S49 H50 T51 A53 A54 Q55 G56 G57 Y170 A172 A206 T207 G208 T218 D226 L257 H358 Y359 G391 E392 R403 A406 S408 L409 U1LRQ3 26198225 SNIAQYKVIDHAYDVVIIGAGGAGLRAAMGLGEAGFKTAVVTKMFPTRSHTTAAQGGINAALGSMNPDDWKWHFYDTVKGSDWLGDQNAMHYLTRNAVEAVTELENFGMPFSRTPEGKIYQRSFGGQSNNYGKGGVAKRTCCVADRTGHSMLHTLYGNSLRCHCTFFIEYFALDLLMDKGRCVGVIALCLEDGTIHRFRSKRTIVATGGYGRAYFSCTTAHMNTGDGTALATRAGIALEDLEFIQFHPTGIYGVGCLITEGSRGEGGFLVNSEGERFMERYAPKAKDLASRDVVSRAETIEIMEGRGVGPEKDHIYLQLHHLPAEQLHQRLPGISETAKIFAGVDVTKEPIPVIPTVHYNMGGIPTNYKAQVIKYTKEGGDKIVPGLYACGECACHSVHGANRLGANSLLDAVVFGRACSINIKEELKPDEKIPELPEGAGEESIANLDAVRYANGDVPTAELRLTMQKTMQKHAGVFRRGDILAEGVKKMMDLFKELKRLKTTDRSLIWNSDLTESLELQNLMLNATQTIVAAENRKESRGAHARDDFPKREDEYDYSKPIEGQTKRPFEKHWRKHTLTKQDPRTGHITLDYRPVIDKTLDPAEVDWIPPIIRSY 4ysx B 2.25 BS01 FES B 1 S88 C89 G92 C94 G95 S96 C97 L107 C109 S56 C57 G60 C62 G63 S64 C65 L75 C77 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysx B 2.25 BS02 SF4 B 1 C182 I183 C185 A186 C188 A206 C249 P250 K251 C150 I151 C153 A154 C156 A174 C217 P218 K219 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysx B 2.25 BS03 F3S B 1 C192 Y202 P205 C239 H240 T241 I242 M243 N244 C245 A256 I259 C160 Y170 P173 C207 H208 T209 I210 M211 N212 C213 A224 I227 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysx B 2.25 BS04 E23 B 1 P193 S194 W197 H240 P161 S162 W165 H208 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysx C 2.25 BS01 E23 B 1 L60 W69 M70 S72 R76 V77 L27 W36 M37 S39 R43 V44 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysx C 2.25 BS02 HEM C 1 H75 R76 G79 M82 A83 H131 T132 H42 R43 G46 M49 A50 H98 T99 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysx C 2.25 BS03 EPH D 1 M82 L133 V170 M49 L100 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysx D 2.25 BS02 HEM C 1 R63 A66 I73 L92 H95 V96 G99 V103 R36 A39 I46 L65 H68 V69 G72 V76 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ysx F 2.25 BS01 FES F 1 R87 S88 C89 G92 C94 G95 C97 L107 C109 R57 S58 C59 G62 C64 G65 C67 L77 C79 1.3.5.1 O44074 26198225 TGKRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysx F 2.25 BS02 SF4 F 1 C182 I183 C185 A186 C187 C188 A206 C249 P250 C152 I153 C155 A156 C157 C158 A176 C219 P220 1.3.5.1 O44074 26198225 TGKRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysx G 2.25 BS01 HEM G 1 H75 R76 G79 M82 A83 H131 T132 G135 I139 H42 R43 G46 M49 A50 H98 T99 G102 I106 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPTNH 4ysx G 2.25 BS02 E23 G 1 L60 W69 M70 S72 R76 L27 W36 M37 S39 R43 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPTNH 4ysx G 2.25 BS03 EPH H 1 M82 T85 L133 V170 M49 T52 L100 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPTNH 4ysx H 2.25 BS01 HEM G 1 R63 A66 M69 V70 I73 H95 V96 G99 V103 R36 A39 M42 V43 I46 H68 V69 G72 V76 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ysy B 3.10 BS02 SF4 B 1 C182 L184 C185 A186 C187 C188 A206 C249 P250 L253 C150 L152 C153 A154 C155 C156 A174 C217 P218 L221 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysy C 3.10 BS02 HEM C 1 H75 R76 G79 C80 M82 A83 H131 T132 G135 H42 R43 G46 C47 M49 A50 H98 T99 G102 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysy C 3.10 BS03 EPH D 1 M82 T85 P127 I128 A129 V170 M49 T52 P94 I95 A96 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysy D 3.10 BS03 EPH D 1 V70 I73 A76 Y77 F78 H80 L88 L92 F150 E151 W154 V43 I46 A49 Y50 F51 H53 L61 L65 F123 E124 W127 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ysy F 3.10 BS01 FES F 1 R87 S88 C89 G92 C94 G95 S96 C97 L107 C109 R55 S56 C57 G60 C62 G63 S64 C65 L75 C77 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysy F 3.10 BS02 SF4 F 1 C182 I183 L184 C185 A186 C187 C188 M209 C249 P250 L253 C150 I151 L152 C153 A154 C155 C156 M177 C217 P218 L221 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysy G 3.10 BS03 EPH H 1 M82 T85 A129 L133 V170 M49 T52 A96 L100 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysy H 3.10 BS02 HEM G 1 R63 A66 V70 I73 H95 V96 G99 V103 R36 A39 V43 I46 H68 V69 G72 V76 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ysy H 3.10 BS03 EPH H 1 V70 I73 A76 Y77 L92 F150 E151 W154 V43 I46 A49 Y50 L65 F123 E124 W127 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ysz B 3.30 BS02 SF4 B 1 C182 I183 C185 A186 C188 A206 M209 C249 P250 C150 I151 C153 A154 C156 A174 M177 C217 P218 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysz B 3.30 BS03 F3S B 1 C192 Y202 C239 H240 T241 I242 M243 N244 C245 A256 C160 Y170 C207 H208 T209 I210 M211 N212 C213 A224 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysz C 3.30 BS02 12J C 1 L60 W69 S72 R76 L27 W36 S39 R43 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysz C 3.30 BS03 EPH D 1 M82 T85 A129 T132 V170 M49 T52 A96 T99 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysz D 3.30 BS01 HEM C 1 R63 A66 M69 V70 I73 H95 V96 G99 R36 A39 M42 V43 I46 H68 V69 G72 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ysz F 3.30 BS02 SF4 F 1 C182 I183 L184 C185 A186 C188 A206 M209 C249 P250 C150 I151 L152 C153 A154 C156 A174 M177 C217 P218 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ysz G 3.30 BS03 EPH H 1 T85 I123 A129 V170 T52 I90 A96 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ysz H 3.30 BS03 EPH H 1 V70 I73 Y77 L92 F150 E151 W154 V43 I46 Y50 L65 F123 E124 W127 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4yt0 B 3.66 BS01 FES B 1 L69 S88 C89 G92 C94 G95 C97 L107 C109 L37 S56 C57 G60 C62 G63 C65 L75 C77 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4yt0 B 3.66 BS02 SF4 B 1 C182 I183 C185 A186 C187 C188 A206 M209 C249 P250 C150 I151 C153 A154 C155 C156 A174 M177 C217 P218 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4yt0 B 3.66 BS04 MRN C 1 P193 W197 H240 P161 W165 H208 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4yt0 C 3.66 BS01 HEM C 1 H75 R76 G79 C80 M82 A83 H131 T132 I139 H42 R43 G46 C47 M49 A50 H98 T99 I106 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4yt0 D 3.66 BS01 HEM C 1 R63 A66 M69 I73 H95 V96 G99 R36 A39 M42 I46 H68 V69 G72 P92507 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4yt0 F 3.66 BS02 SF4 F 1 C182 I183 C185 A186 C188 A206 M209 C249 P250 L253 P255 C150 I151 C153 A154 C156 A174 M177 C217 P218 L221 P223 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4yt0 F 3.66 BS04 MRN G 1 P193 W196 W197 H240 P161 W164 W165 H208 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4yt0 G 3.66 BS01 HEM G 1 H75 R76 G79 M82 A83 H131 T132 F138 H42 R43 G46 M49 A50 H98 T99 F105 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKAT 4yt0 H 3.66 BS01 HEM G 1 R63 A66 V70 I73 H95 V96 G99 R36 A39 V43 I46 H68 V69 G72 26198225 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ytm B 3.40 BS01 FES B 1 R87 S88 C89 C94 G95 C97 L107 C109 R55 S56 C57 C62 G63 C65 L75 C77 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ytm B 3.40 BS03 F3S B 1 C192 Y202 C239 H240 T241 M243 N244 C245 A256 I259 C160 Y170 C207 H208 T209 M211 N212 C213 A224 I227 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ytm C 3.40 BS01 HEM C 1 H75 R76 G79 C80 M82 A83 H131 T132 H42 R43 G46 C47 M49 A50 H98 T99 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLP 4ytm C 3.40 BS03 EPH D 1 M82 T85 I128 I166 V170 M49 T52 I95 I133 V137 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLP 4ytm F 3.40 BS04 F6A G 1 P193 S194 W196 W197 H240 I242 P163 S164 W166 W167 H210 I212 1.3.5.1 O44074 26198225 TGKRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ytn B 3.00 BS03 F3S B 1 C192 S194 Y202 C239 H240 T241 I242 M243 N244 C245 A256 I259 C160 S162 Y170 C207 H208 T209 I210 M211 N212 C213 A224 I227 1.3.5.1 O44074 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ytn B 3.00 BS04 FD8 C 1 P193 W197 I242 P161 W165 I210 1.3.5.1 O44074 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 4ytn C 3.00 BS02 FD8 C 1 L60 S72 G73 R76 L27 S39 G40 R43 P92506 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ytn D 3.00 BS01 HEM C 1 R63 A66 M69 I73 L92 H95 V96 G99 V103 R36 A39 M42 I46 L65 H68 V69 G72 V76 P92507 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ytn D 3.00 BS02 FD8 C 1 D106 Y107 R109 D79 Y80 R82 P92507 TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL 4ytn G 3.00 BS01 FD8 F 1 L60 S72 R76 L27 S39 R43 P92506 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 4ytp A 3.10 BS01 FAD A 1 G26 A27 G28 G29 A30 V48 T49 K50 L51 S56 H57 T58 A61 G63 G64 Y177 F178 A179 T214 G215 T225 D233 L264 H365 Y366 E398 R409 A412 N413 S414 L415 L418 G17 A18 G19 G20 A21 V39 T40 K41 L42 S47 H48 T49 A52 G54 G55 Y168 F169 A170 T205 G206 T216 D224 L255 H356 Y357 E389 R400 A403 N404 S405 L406 L409 1.3.5.1 Q0QF01 26198225 STQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRARNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLAVRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKPNAGEESVMNLDKLRFANGTIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKILRLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKERVDEYDYSKPIQGQQKKPFQEHWRKHTLSYVDVKTGKVSLEYRPVIDKTLNEADCATVPPAIRSY 4ytp B 3.10 BS02 SF4 B 1 C158 I159 L160 C161 A162 C164 A182 C225 P226 L229 C150 I151 L152 C153 A154 C156 A174 C217 P218 L221 1.3.5.1 Q007T0 26198225 PRIKKFAIYRWDPDKTGDKPHMQTYEIDLNNCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLDKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTGTCPKGLNPGKAIAEIKKMMATYKE 4ytp B 3.10 BS03 F3S B 1 C168 S170 Y178 C215 H216 T217 I218 M219 N220 C221 G232 C160 S162 Y170 C207 H208 T209 I210 M211 N212 C213 G224 1.3.5.1 Q007T0 26198225 PRIKKFAIYRWDPDKTGDKPHMQTYEIDLNNCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLDKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTGTCPKGLNPGKAIAEIKKMMATYKE 4ytp C 3.10 BS02 E23 C 1 I30 S42 I43 R46 I25 S37 I38 R41 D0VWV4 26198225 TTAKEEMERFWNKNLGSNRPLSPHITIYRWSLPMAMSICHRGTGIALSAGVSLFGLSALLLPGNFESHLELVKSLCLGPTLIYTAKFGIVFPLMYHTWNGIRHLIWDLGKGLTIPQLTQSGVVVLILTVLSSVGLAAM 4ytp D 3.10 BS01 HEM C 1 R47 S50 L53 L54 H79 G83 I84 R13 S16 L19 L20 H45 G49 I50 A5GZW8 26198225 SSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKVAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL 4yu7 B 1.65 BS01 DHC B 1 K15 N16 K19 K15 N16 K19 P58399 26192963 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKLYRYHLKPFCKKADDC 4yu7 B 1.65 BS02 DHC B 2 K19 K105 R108 K19 K105 R108 P58399 26192963 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKLYRYHLKPFCKKADDC 4yu7 A 1.65 BS01 DHC A 1 T72 I94 R97 E98 T72 I94 R97 E98 P58399 26192963 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKLYRYHLKPFCKKADDC 4yu7 A 1.65 BS02 DHC A 2 K15 K19 K105 R108 K15 K19 K105 R108 P58399 26192963 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKLYRYHLKPFCKKADDC 4ywc A 2.40 BS01 III C 1 S18 Q53 Q74 W92 G93 D94 Y96 Y97 I129 E142 E143 E148 L152 M155 S1 Q13 Q34 W52 G53 D54 Y56 Y57 I79 E84 E85 E90 L94 M97 Q9FIP9 SAAAPQFNEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGENTAEQEHRKRVIRELNSLISGNDEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNF 4ywc B 2.40 BS01 III D 1 S18 W92 G93 D94 Y97 L125 N126 I129 E142 E143 V144 L152 M155 T156 S1 W51 G52 D53 Y56 L75 N76 I79 E84 E85 V86 L94 M97 T98 Q9FIP9 SAAAQFNEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGEENTAEQEHRKRVIRELNSLISGNDEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNF 4ywy A 1.95 BS02 PBD A 1 D159 E201 E202 W207 D248 L249 Y299 V302 I303 Q304 F325 W329 H330 D125 E166 E167 W172 D213 L214 Y264 V267 I268 Q269 F290 W294 H295 2.3.2.5 Q16769 AWPEEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPEGERSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLSLKTVSDSPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHGMDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLHL 4yz6 A 1.95 BS01 III B 1 Q53 Q74 W92 G93 D94 Y96 Y97 I122 L125 N126 I129 E142 E143 V144 F151 L152 M155 T156 Q10 Q31 W49 G50 D51 Y53 Y54 I70 L73 N74 I77 E79 E80 V81 F88 L89 M92 T93 Q9FIP9 QPQFNEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGETNTAEQEHRKRVIRELNSLISEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNFN 4yz7 A 1.96 BS01 9AR B 1 L111 P113 L111 P113 P58399 26192963 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKLYRYHLKPFCKKADDC 4yz7 B 1.96 BS01 9AR B 1 L10 Q11 L10 Q11 P58399 26192963 SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKLYRYHLKPFCKKADDC 4z88 A 2.09 BS01 III M 1 F1324 Y1326 M1331 P1333 N1334 D1336 E1340 D1359 G1360 F1361 Y1372 P1374 H1375 N1376 M1377 F7 Y9 M14 P16 N17 D19 E23 D42 G43 F44 Y55 P57 H58 N59 M60 A0A0B4JDC9 RYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVE 4z88 B 2.09 BS01 III N 1 F1324 Y1326 P1333 P1374 H1375 N1376 M1377 F8 Y10 P17 P58 H59 N60 M61 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVE 4z88 C 2.09 BS01 III O 1 F1324 D1325 Y1326 P1333 N1334 D1359 G1360 F1361 P1374 H1375 N1376 F8 D9 Y10 P17 N18 D43 G44 F45 P58 H59 N60 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z88 D 2.09 BS01 III P 1 F1324 Y1326 P1333 N1334 D1336 D1359 F1361 P1374 H1375 N1376 M1377 F12 Y14 P21 N22 D24 D47 F49 P62 H63 N64 M65 A0A0B4JDC9 GSPEFRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVE 4z88 G 2.09 BS01 III S 1 F1324 Y1326 P1333 N1334 D1336 E1340 E1341 D1359 G1360 F1361 Y1372 P1374 H1375 N1376 F10 Y12 P19 N20 D22 E26 E27 D45 G46 F47 Y58 P60 H61 N62 A0A0B4JDC9 PEFRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z88 H 2.09 BS01 III T 1 Y1326 P1333 N1334 D1336 E1341 D1359 F1361 Y1372 N1376 Y14 P21 N22 D24 E29 D47 F49 Y60 N64 A0A0B4JDC9 GSPEFRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVE 4z88 I 2.09 BS01 III U 1 F1324 D1325 Y1326 M1331 P1333 N1334 D1336 E1341 D1359 G1360 F1361 Y1372 P1374 H1375 N1376 F8 D9 Y10 M15 P17 N18 D20 E25 D43 G44 F45 Y56 P58 H59 N60 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVE 4z89 A 2.64 BS01 III a 1 M1323 F1324 Y1326 P1333 N1334 D1336 E1340 E1341 D1359 G1360 F1361 P1374 H1375 N1376 M1377 M7 F8 Y10 P17 N18 D20 E24 E25 D43 G44 F45 P58 H59 N60 M61 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z89 B 2.64 BS01 III b 1 F1324 Y1326 P1333 N1334 E1341 D1359 G1360 F1361 Y1372 P1374 H1375 N1376 M1377 F8 Y10 P17 N18 E25 D43 G44 F45 Y56 P58 H59 N60 M61 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z89 D 2.64 BS01 III d 1 M1323 F1324 Y1326 P1333 N1334 E1341 E1346 D1357 D1359 G1360 F1361 Y1372 P1374 H1375 N1376 M1377 M7 F8 Y10 P17 N18 E25 E30 D41 D43 G44 F45 Y56 P58 H59 N60 M61 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z89 H 2.64 BS01 III h 1 F1324 Y1326 M1331 P1333 N1334 D1336 G1337 E1341 D1359 F1361 P1374 H1375 N1376 M1377 F7 Y9 M14 P16 N17 D19 G20 E24 D42 F44 P57 H58 N59 M60 A0A0B4JDC9 RYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z89 I 2.64 BS01 III i 1 F1324 Y1326 M1331 P1333 N1334 D1359 F1361 Y1372 P1374 H1375 N1376 M1377 F8 Y10 M15 P17 N18 D43 F45 Y56 P58 H59 N60 M61 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEV 4z89 J 2.64 BS01 III j 1 M1323 F1324 P1333 N1334 D1359 F1361 Y1372 P1374 H1375 N1376 M1377 M7 F8 P17 N18 D43 F45 Y56 P58 H59 N60 M61 A0A0B4JDC9 FRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVE 4z8a A 1.76 BS01 III B 1 I1448 L1450 Y1451 Y1453 L1458 P1460 N1461 D1463 V1467 E1468 T1473 G1474 D1486 G1487 F1488 L1499 P1501 N1503 F1504 I16 L18 Y19 Y21 L26 P28 N29 D31 V35 E36 T41 G42 D54 G55 F56 L67 P69 N71 F72 A0A0B4JDC9 GPLGSPEFNRPVKRMIALYDYDPQELSPNVDAEQVELCFKTGEIILVYGDMDEDGFYMGELDGVRGLVPSNFLAD 4zh2 C 4.20 BS01 4OB C 1 V550 P552 Y555 G640 E641 S642 V548 P550 Y553 G638 E639 S640 2.7.7.6 P0A8V2 26190576 YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 4zh2 D 4.20 BS01 4OB C 1 K749 P750 I755 L770 F773 I774 K742 P743 I748 L763 F766 I767 2.7.7.6 P0A8T7 26190576 LKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTTGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 4zh2 I 4.20 BS01 4OB I 1 P552 Y555 R637 G640 E641 S642 P550 Y553 R635 G638 E639 S640 2.7.7.6 P0A8V2 26190576 YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 4zh2 J 4.20 BS01 4OB I 1 K749 P750 I755 L770 F773 I774 K734 P735 I740 L755 F758 I759 2.7.7.6 P0A8T7 26190576 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 4zh3 J 4.08 BS04 4OD J 1 K749 P750 I755 L770 F773 I774 H777 K719 P720 I725 L740 F743 I744 H747 2.7.7.6 P0A8T7 26190576 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 4zh4 D 3.99 BS01 4OE C 1 K749 P750 I755 F773 I774 K727 P728 I733 F751 I752 2.7.7.6 P0A8T7 26190576 LKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTTGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAG 4zhc A 2.04 BS01 TC2 A 1 L36 A40 I41 Q49 Y52 Y106 F123 K125 Y132 K134 L33 A37 I38 Q46 Y49 Y103 F120 K122 Y129 K131 P80188 TSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 4zhc B 2.04 BS01 TC2 B 1 A40 Y52 Y106 F123 K125 Y132 K134 A35 Y43 Y97 F114 K116 Y123 K125 P80188 DLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4zhd B 2.05 BS01 4OZ B 1 I41 Y106 F123 K125 Y132 K134 I36 Y101 F118 K120 Y127 K129 P80188 DLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4zhf A 2.45 BS01 4OL A 1 A40 I41 Y52 S68 L70 W79 R81 Y100 Y106 F123 K125 Y132 K134 A39 I40 Y51 S67 L69 W78 R80 Y99 Y105 F122 K124 Y131 K133 P80188 DSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 4zhf B 2.45 BS01 4OL B 1 I41 Y52 S68 L70 W79 Y100 Y106 F123 K125 Y132 F133 K134 I39 Y50 S66 L68 W77 Y98 Y104 F121 K123 Y130 F131 K132 P80188 STSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4zhf E 2.45 BS01 4OL E 1 A40 I41 Y52 S68 L70 W79 R81 Y106 F123 K125 Y132 F133 K134 A39 I40 Y51 S67 L69 W78 R80 Y105 F122 K124 Y131 F132 K133 P80188 DSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4zhg C 2.05 BS01 4OL C 1 I41 Y52 S68 W79 R81 Y100 Y106 F123 K125 Y132 K134 I39 Y50 S66 W77 R79 Y98 Y104 F121 K123 Y130 K132 P80188 STSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4zlo A 2.50 BS01 4PV A 1 E315 V318 M319 N322 I327 V328 F379 L380 N383 V385 H387 L405 T406 E59 V62 M63 N66 I71 V72 F123 L124 N127 V129 H131 L149 T150 2.7.11.1 Q13153 26191365 DEEILEKLRSIVSVGDPKKKYTRFEKIGQSGTVYTAMDVATGQEVAIKQMNKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKN 4zpe A 1.70 BS01 4QA A 1 L30 D32 Y71 T72 Q73 G74 K107 F108 I110 W115 Y198 K224 G230 T231 T232 T329 L34 D36 Y75 T76 Q77 G78 K111 F112 I114 W119 Y189 K215 G221 T222 T223 T316 3.4.23.46 P56817 26195137 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVESQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACDEFRTAAVEGPFVTLDMEDCGYN 4zpf A 1.80 BS01 4QD A 1 G11 Q12 G13 L30 D32 Y71 T72 Q73 G74 F108 I110 W115 Y198 K224 G230 T231 T232 T329 V332 G15 Q16 G17 L34 D36 Y75 T76 Q77 G78 F112 I114 W119 Y191 K217 G223 T224 T225 T317 V320 3.4.23.46 P56817 26195137 GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHDEFRTAAVEGPFVTLDMEDCGYN 4zpi A 2.50 BS01 FE2 A 1 H102 K137 E202 H206 H92 K127 E192 H196 Q2MFS1 ALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4zpi B 2.50 BS01 FE2 B 1 H102 K137 H206 H91 K126 H195 Q2MFS1 ALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4zpi C 2.50 BS01 FE2 C 1 H102 E202 H206 H94 E194 H198 Q2MFS1 PALTREQLYIFDTTGFLVIPGVFGSGEVESFRSELERLDRTRRYPDLPAASPVFARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDLSITHTYHDGKLYCPYVKALVYLSDIQSPEDGSFCYVQGSHKANFPLLRERAERGENTSLVDSGFPTLSDVFVRSGDVLLLNEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV 4zwy A 1.50 BS02 4SN A 1 W5 F20 H94 H96 H119 F131 G132 L198 T199 P201 P202 W209 W2 F17 H91 H93 H116 F127 G128 L194 T195 P197 P198 W205 4.2.1.1 P00918 26203869 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4zwz A 1.62 BS02 510 A 1 N62 H64 L91 Q92 H94 H96 H119 V121 V131 L141 L198 T199 T200 W209 N59 H61 L88 Q89 H91 H93 H116 V118 V127 L137 L194 T195 T196 W205 4.2.1.1 P00918 26203869 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5a0p A 1.40 BS01 ZN A 1 H142 H146 E185 H117 H121 E160 3.4.24.- 26211609 MDSTTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK 5a0r A 1.25 BS01 III D 1 Y94 L95 P100 K101 W103 W110 G115 L116 G117 G118 S119 H142 H146 H150 K158 Y178 E185 Y66 L67 P72 K73 W75 W82 G87 L88 G89 G90 S91 H114 H118 H122 K130 Y150 E157 3.4.24.- 26211609 TTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHATAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK 5a0r B 1.25 BS01 III E 1 Y94 L95 P100 K101 W110 V113 G115 L116 G117 G118 S119 H142 H146 Y178 E185 Y66 L67 P72 K73 W82 V85 G87 L88 G89 G90 S91 H114 H118 Y150 E157 3.4.24.- 26211609 TTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHATAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK 5a0x A 1.70 BS01 III C 1 Y94 L95 P100 K101 G102 W103 W110 V113 G115 L116 G117 G118 S119 H134 D135 A136 L139 H142 H146 H150 N175 F178 L179 E185 E189 Y68 L69 P74 K75 G76 W77 W84 V87 G89 L90 G91 G92 S93 H108 D109 A110 L113 H116 H120 H124 N149 F152 L153 E159 E163 3.4.24.- Q183R7 26211609 DSTTIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHATAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNFLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK 5a46 A 2.63 BS01 38O A 1 L484 V492 A512 I545 V561 E562 Y563 A564 S565 G567 L630 L21 V29 A49 I82 V98 E99 Y100 A101 S102 G104 L157 26203596 ELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 5a4c A 2.09 BS01 XOJ A 1 K482 L484 G485 E486 V492 A512 K514 E531 M535 I545 V559 V561 E562 Y563 A564 S565 K566 G567 L630 A640 D641 F642 K19 L21 G22 E23 V27 A47 K49 E66 M70 I80 V94 V96 E97 Y98 A99 S100 K101 G102 L165 A175 D176 F177 26203596 ELPEDPRWELPRDRLVLGKPLGEFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYSYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 5a5y A 1.92 BS01 MG A 1 E4 E169 E5 E170 3.6.1.3,3.6.1.25 AMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRRAVLRLRFLQNAAVSAASPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECVESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLEVDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVFRSGKLP 5a5y A 1.92 BS02 3PO A 1 E4 K6 R52 R54 K76 R143 E169 T199 K200 E5 K7 R53 R55 K77 R144 E170 T200 K201 3.6.1.3,3.6.1.25 AMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRRAVLRLRFLQNAAVSAASPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECVESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLEVDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVFRSGKLP 5a60 A 1.82 BS01 MG A 1 E6 E160 E7 E161 3.6.1.25 AMAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAAFELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHALMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQPLGDRYHDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWL 5a60 A 1.82 BS02 MG A 2 E4 E6 E162 E5 E7 E163 3.6.1.25 AMAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAAFELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHALMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQPLGDRYHDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWL 5a60 A 1.82 BS03 3PO A 1 E4 E6 K8 R56 R58 K69 R81 F124 R126 E160 S190 K191 E5 E7 K9 R57 R59 K70 R82 F125 R127 E161 S191 K192 3.6.1.25 AMAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAAFELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHALMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQPLGDRYHDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWL 5a61 A 1.50 BS03 MN A 2 E4 E6 E160 E162 E5 E7 E161 E163 3.6.1.25 AMAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAAFELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHALMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQPLGDRYHDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWL 5a64 A 2.10 BS01 V4E A 1 K11 Y39 D51 W53 R55 R57 K65 Y79 R125 E157 E159 A192 K193 K8 Y36 D48 W50 R52 R54 K62 Y76 R122 E145 E147 A180 K181 3.6.1.28 GLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPGVTGVSGPHNEYVEVTSEAAIVAQLFELLGSGEQKPAGVAAVLGSLKLQEVASFITTRSSWKLAQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEAASS 5a64 B 2.10 BS01 V4E B 1 K11 Y39 W53 R55 R57 K65 N77 Y79 R125 E157 E159 A192 K193 L194 M195 K8 Y36 W50 R52 R54 K62 N66 Y68 R114 E137 E139 A172 K173 L174 M175 3.6.1.28 GLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPHNEYVEVTSEAAIVAQLFELLGSGEQKPAGVAAVLGSLKLQEVASFITTRSSWKLAQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEA 5a65 A 1.98 BS01 MG A 1 E157 E159 E151 E153 3.6.1.28 GAMTQGLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPGVSGPHNEYVEVTSEAAIVAQLFELLGSGEQKPAGVAAVLGSLKLQEVASFITTRSSWKLALSEPQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEAAS 5a65 A 1.98 BS02 MG A 2 R125 D145 E159 R124 D139 E153 3.6.1.28 GAMTQGLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPGVSGPHNEYVEVTSEAAIVAQLFELLGSGEQKPAGVAAVLGSLKLQEVASFITTRSSWKLALSEPQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEAAS 5a65 A 1.98 BS03 TPP A 1 K11 Y39 W53 R55 R57 Y79 A192 K193 M195 K13 Y41 W55 R57 R59 Y78 A186 K187 M189 3.6.1.28 GAMTQGLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPGVSGPHNEYVEVTSEAAIVAQLFELLGSGEQKPAGVAAVLGSLKLQEVASFITTRSSWKLALSEPQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEAAS 5a65 B 1.98 BS03 TPP B 1 K11 Y39 W53 R55 R57 Y79 P191 A192 K193 L194 M195 K13 Y41 W55 R57 R59 Y73 P174 A175 K176 L177 M178 3.6.1.28 GAMTQGLIEVERKFAPGPDTEERLQELGATLEHRVTFRDTYYDTSELSLMLSDHWLRQREGSGWELKCPHNEYVEVTSEAAIVAQLFELLPAGVAAVLGSLKLQEVASFITTRSSWKLALSEPQLTIDLDSADFGYAVGEVEAMVHEKAEVPAALEKIITVSSMLGVPAQEEAPAKLMVYLQRFRPLDYQRLLEAAS 5a67 A 1.30 BS02 3PO A 1 E2 E4 K6 R52 R54 K76 R143 E169 T199 K200 E4 E6 K8 R54 R56 K72 R139 E165 T195 K196 3.6.1.3,3.6.1.25 GAMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRRAVLRLRFLQNAPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECVESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLEVDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVFRSGKLP 5a68 A 1.67 BS01 MN A 1 E2 E4 E169 E171 E4 E6 E165 E167 3.6.1.3,3.6.1.25 GAMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRRAVLRLRFLQNAPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECVESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLEVDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVFRSG 5a68 A 1.67 BS03 MN A 3 E2 K76 E90 E171 E4 K72 E86 E167 3.6.1.3,3.6.1.25 GAMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRRAVLRLRFLQNAPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECVESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLEVDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVFRSG 5a9g A 1.35 BS01 MN A 1 H26 H76 D163 H167 H30 H80 D167 H171 1.15.1.1 26198187 DPFTQFKQTPLPYAYDALEGAIDAKTMEIHYSKHAAGYTANLNKAIAGTPAEKESIENILAKVSQYSDAVRNNAGGHYNHELFWSILTPNKGTKPSAALQKAIDETFGSLDALKEKINAAGAARFGSGWAWLIVDNGGKLQVTSTPNQDNPLMDFTKEKGTPILGIDVWEHAYYLRYQNKRADYLTTIWDVINWEEVSARYEKALK 5awm A 1.79 BS01 ANP A 1 I30 G31 I37 V38 A51 K53 M106 E107 L108 M109 N112 S153 N154 V156 L166 I24 G25 I27 V28 A41 K43 M96 E97 L98 M99 N102 S143 N144 V146 L156 2.7.11.24 P92208 QHYTVEVGDTNFTIHSRYINLRPIGGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVREHTVEQWKELIYEEVMDY 5bnw A 2.40 BS01 III D 1 H496 H498 H499 N557 H558 P559 D587 T633 K634 Q839 F868 V895 H183 H185 H186 N244 H245 P246 D274 T320 K321 Q505 F534 V561 2.4.1.255 O15294 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDIYDNRIVLNGIDLKAFLDSLPDVKIVKMKNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 5bon A 1.80 BS01 MG A 1 G47 G48 E67 G39 G40 E59 3.6.1.55 Q9NV35 GRRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNHL 5bon A 1.80 BS02 MG A 2 E63 E67 E55 E59 3.6.1.55 Q9NV35 GRRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNHL 5bon B 1.80 BS01 MG B 1 G47 E63 E67 G38 E54 E58 3.6.1.55 Q9NV35 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNH 5bon B 1.80 BS02 MG B 2 G48 E63 G39 E54 3.6.1.55 Q9NV35 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNH 5bon F 1.80 BS03 MG F 3 G48 H49 E63 G39 H40 E54 3.6.1.55 Q9NV35 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNHL 5bs2 B 1.97 BS01 III R 1 S56 L57 F60 R64 L67 M89 S13 L14 F17 R21 L24 M46 4.1.1.39 A8HQH2 ASPERKAAVALRSLFTFVAARVVLEQLQGPGGPETTYNQQAYLDLMDFLGTPMKGDGGDEWMAAVMRKNHALALRLMEVREAYLDEFEWGKTMEMASRETREANTRLMRAAAM 5buv A 1.75 BS01 CYT A 1 E48 H139 E49 H140 A1JNA0 26174084 ASIINITELNISGCYLIESPIFSDERGEFVKTHHQEIFKNFGLEIPSAEEYYSRSKNNVIRGMHFQQYPDDHNKLVFCPEGEVLDVFLDIRKDSNTYGQFMSFILNPHNRRSIFLAKGIAHGFLSMKDNTLIVCKTSTVHSPSRDSGIHWNSFGFKWPVENPIISDKDRNLDCF 5buv B 1.75 BS01 CYT B 1 E48 Y50 H139 E48 Y50 H139 A1JNA0 26174084 SIINITELNISGCYLIESPIFSDERGEFVKTHHQEIFKNFGLEIPSAEEYYSRSKNNVIRGMHFQQYPDDHNKLVFCPEGEVLDVFLDIRKDSNTYGQFMSFILNPHNRRSIFLAKGIAHGFLSMKDNTLIVCKTSTVHSPSRDSGIHWNSFGFKWPVENPIISDKDRNLDCF 5buv C 1.75 BS01 CYT A 1 F28 K30 F31 K33 A1JNA0 26174084 HMASIINITELNISGCYLIESPIFSDERGEFVKTHHQEIFKNFGLEIPSAEEYYSRSKNNVIRGMHFQQYPDDHNKLVFCPEGEVLDVFLDIRKDSNTYGQFMSFILNPHNRRSIFLAKGIAHGFLSMKDNTLIVCKTSTVHSPSRDSGIHWNSFGFKWPVENPIISDKDRNLDCF 5bv0 A 3.10 BS01 III C 1 F317 A318 L324 N325 A328 K332 Y335 K365 N369 E372 I375 R379 L387 Q391 D504 E508 S519 F290 A291 L297 N298 A301 K305 Y308 K338 N342 E345 I348 R352 L360 Q364 D477 E481 S492 G0SCM5 AGFDAEQVRDKARKDLLHLLEGVRGKKNLVIEKDLAGPLGVIVKASTLRDYGVDNFFFLENKNTGTSQRNIVFIARGESVRNAHAIAAQIKRIQRESQTSHDFHIFWVPRRTLFSDKVLEEAGVLGDANISELPLYFFPLERDVLSLELNDSFRDLYLAKDPTPVFLLSRALMGIQKKHGLFPRIIGKGENAKRVADLLSRMRQELLAGEEAGESDRAGLSPSTTIESVIIIDREVDFVTPLLTQLTYEGLIDEYFGIQNNQTDVDAVRKRKIQLDGSDSLYSQLRDANFAIVGSLLNTVARRLKSDYESRHNTKTTAELKEFVKKLPGYQAEQQSLKIHSNIAEEIINYTRTEIFNKLLEVQQNLAAGADPSSQFDSIEELVARDTPLPQVLRLLCLYSCISGGIKTKELDHFRRLVLQGYGHQHLLTLHNLERLQMFLSKSSPLASMITMSGSSGGPDQKTNYTYLRKQLRLIVDEVNEQDPNDIAYVYSGYAPLSIRLVQCVLQKQYLLSITKGGGAQGWKGFEEIVKHARGPTFDEIQKGDKKTVFVVFVGGITFTEIAALRFIAKQEEARRNIVICTTSIINGNRMMNAAIETATFEKT 5bvk A 2.29 BS01 4VC A 1 K655 E672 M676 L679 I685 M699 T701 F762 A783 D784 F785 K36 E53 M57 L60 I66 M80 T82 F129 A150 D151 F152 2.7.10.1 Q08345 26191369 DFPRSRLRFKEKLGEGQFGEVHLCEVDSHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALN 5bvo A 1.98 BS01 4VE A 1 A653 K655 E672 I675 M676 L679 I685 M699 T701 D702 M704 F762 L773 A783 D784 F785 A32 K34 E51 I54 M55 L58 I64 M78 T80 D81 M83 F127 L138 A148 D149 F150 2.7.10.1 Q08345 26191369 DFPRSRLRFKEKLGEFGEVHLCEVDSHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALN 5bvs A 2.20 BS01 EIC A 1 F17 L24 V26 A34 P39 T54 T57 F58 A76 D77 V116 R127 Y129 F17 L24 V26 A34 P39 T54 T57 F58 A76 D77 V116 R127 Y129 26206084 MCDQFVGTWKFLSSENFEDYMKELGVGFATRKMAGVAKPNVTISINGDVITIKTESTFKNTEVSFRLGEEFDETTADDRKTKNVITLDNGILNQVQKWDGKETVIKRKVMDGNLVVECTMNTVTSKRVYERA 5bvs B 2.20 BS01 EIC B 1 F17 M21 L24 A34 P39 T57 F58 D77 C118 R127 Y129 F17 M21 L24 A34 P39 T57 F58 D77 C118 R127 Y129 26206084 MCDQFVGTWKFLSSENFEDYMKELGVGFATRKMAGVAKPNVTISINGDVITIKTESTFKNTEVSFRLGEEFDETTADDRKTKNVITLDNGILNQVQKWDGKETVIKRKVMDGNLVVECTMNTVTSKRVYERA 5bvw A 1.94 BS01 1N1 A 1 L616 A653 K655 E672 M676 I685 M699 T701 D702 Y703 M704 E705 G707 L773 A783 F785 L13 A34 K36 E53 M57 I66 M80 T82 D83 Y84 M85 E86 G88 L140 A150 F152 2.7.10.1 Q08345 26191369 DFPRSRLRFKEKLGEGQFGEVHLCEVDSHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALN 5bwd A 2.00 BS01 FUM A 1 L492 C493 M494 S495 R508 G512 G513 W613 N615 Q707 L487 C488 M489 S490 R503 G507 G508 W608 N610 Q702 4.1.99.11 O68395 VSAKVLEYKGKKLNFTPEDPAEETIPADELHEHLQKPSTARTKRLKERCRWKHASAGEFIEKSVTAGIERMRYLTEAHKASEGKPEAIRRALGLANVLNKSTLVLQEDEFIVGYHAEDPNMFPLYPELSHMAVQDYLRSDYSPQPADEAAAINEYWKPHSLQSKCQPYFDPADLGRMYQVSSMEAPSFASGYNSIVPPYETVLEDGLLARIKLAEKHIAEAQADMSTFPWNGTKGLDNIAKIDNWKAMVIACKAVISWARRQGRLCKIVAENFETDPKRQAELLEIADICQRIPAEPCKGLKDAMQAKFFTFLICHAIERYASGYAQKEDTLLWPYYKASVVDKKFQPMSHMDAVELVEMERLKISEHGAGKSRAYREIFPGSNDLFILTVGGTNAKGEDACNDMTDAILEAAKRIRTAEPSIVFRYSKKNREKTLRWVFECIRDGLGYPSIKHDEIGTEQMKEYAKFSLNGNGATDEEAHNWVNVLCMSPGIHGRRKTQKTRSEGGGSIFPAKLLEISLNDGYDWSYADMQLGPKTGDLSSLKSFEDVWEAFRKQYQYAINLCISTKDVSRYFEQRFLQMPFVSAIDDGCMELGMDACALSEQPNGWHNPITTIVAANSLVAIKKLVFEEKKYTLEQLSQALKANWEGFEEMRVDFKRAPKWGNDDDYADGIITRFYEEIIGGEMRKITNYSGGPVMPTGQAGSRTGPTPDGRFGGEAADDGGISPYMGTDKKGPTAVLRSVSKVQKNQKGNLLNQRLSVPIMRSKHGFEIWNSYIKTWHDLNIDHVQFNVVSTDEMRAAQREPEKHHDLIVRVSGYSARFVDIPTYGQNTIIARQEQDFSASDLEFLNVEI 5bwe A 3.30 BS02 MBN A 1 E189 Y197 I384 F385 L391 L492 C493 R508 S514 N615 Q707 V709 L711 E181 Y189 I376 F377 L383 L484 C485 R500 S506 N607 Q699 V701 L703 4.1.99.11 O68395 KVLEYKGKKLNFTPEDPAEETIPADELHEHLQKPSTARTKRLKERCRWKHASAGEFIEKSVTAGIERMRYLTEAHKASEGKPEAIRRALGLANVLNKSTLVLQEDEFIVGYHAEDPNMFPLYPELSHMAVQDYLRSDYSPQPADEAAAINEYWKPHSLQSKCQPYFDPADLGRMYQVSSMEAPSFASGYNSIVPPYETVLEDGLLARIKLAEKHIAEAQADMSTFPWNGTKGLDNIAKIDNWKAMVIACKAVISWARRQGRLCKIVAENFETDPKRQAELLEIADICQRIPAEPCKGLKDAMQAKFFTFLICHAIERYASGYAQKEDTLLWPYYKASVVDKKFQPMSHMDAVELVEMERLKISEHGAGKSRAYREIFPGSNDLFILTVGGTNAKGEDACNDMTDAILEAAKRIRTAEPSIVFRYSKKNREKTLRWVFECIRDGLGYPSIKHDEIGTEQMKEYAKFSLNGNGATDEEAHNWVNVLCMSPGIHGRRKTQKTRSEGGGSIFPAKLLEISLNDGYDWSYADMQLGPKTGDLSSLKSFEDVWEAFRKQYQYAINLCISTKDVSRYFEQRFLQMPFVSAIDDGCMELGMDACALSEQPNGWHNPITTIVAANSLVAIKKLVFEEKKYTLEQLSQALKANWEGFEEMRVDFKRAPKWGNDDDYADGIITRFYEEIIGGEMRKITNYSGGPVMPTGQAVGLYMEVGSRTGPTPDGRFGGEAADDGGISPYMGTDKKGPTAVLRSVSKVQKNQKGNLLNQRLSVPIMRSKHGFEIWNSYIKTWHDLNIDHVQFNVVSTDEMRAAQREPEKHHDLIVRVSGYSARFVDIPTYGQNTIIARQEQDFSASDLEFLNVEI 5bwe B 3.30 BS01 SF4 B 1 P16 C26 C29 W31 Q32 C44 A46 T66 C67 H70 P4 C14 C17 W19 Q20 C32 A34 T54 C55 H58 O68396 QNQPHTEVGTARPCRSCKWQTPDPTDPHRGQCTANRHAMGGVWKRWLRDVENTTCSRHEEGKLSFRDHV 5bwe F 3.30 BS01 SF4 F 1 P16 C26 C29 W31 Q32 C44 A46 C67 H70 P4 C14 C17 W19 Q20 C32 A34 C55 H58 O68396 QNQPHTEVGTARPCRSCKWQTPDPTDPHRGQCTANRHAMGGVWKRWLRDVENTTCSRHEEGKLSFRDHV 5byi A 1.15 BS02 HGB A 1 V134 Q135 Q136 P137 E204 C205 V131 Q132 Q133 P134 E201 C202 4.2.1.1 P00918 26199669 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5c0x B 3.81 BS01 NUC R 1 K83 E94 R95 K83 E94 R95 P46948 MSRLEIYSPEGLRLDGRRWNELRRFESSINTHPHAADGSSYMEQGNNKIITLVKGPKEPRLKSQMDTSKALLNVSVNITKFSKFERSKSSHKNERRVLEIQTSLVRMFEKNVMLNIYPRTVIDIEIHVLEQDGGIMGSLINGITLALIDAGISMFDYISGISVGLYDTTPLLDTNSLEENAMSTVTLGVVGKSEKLSLLLVEDKIPLDRLENVLAIGIAGAHRVRDLMDEELRKHAQKRVSNAS 5c0x G 3.81 BS01 NUC R 1 F80 S81 R110 F80 S81 R110 Q08285 MSTFIFPGDSFPVDPTTPVKLGPGIYCDPNTQEIRPVNTGVLHVSAKGKSGVQTAYIDYSSKRYIPSVNDFVIGVIIGTFSDSYKVSLQNFSSSVSLSYMAFPNASKKNRPTLQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFARQLLFNNDFPLLKVLAAHTKFEVAIGLNGKIWVKCEELSNTLACYRTIMECCQKNDTAAFKDIAKRQFKEILTV 5c0x H 3.81 BS01 NUC R 1 R123 Q174 S175 R90 Q141 S142 P38792 SEVITITKRNGAFQNSSDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETGDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLLNAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNGYIWLRKTSQMDLARDTSSWQIYSDENDPSISNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESIGSDILTAEKMRG 5c0x J 3.81 BS01 NUC R 1 D543 P544 C547 D549 I550 N551 D552 Y595 Y654 L696 S698 E728 M731 L732 R753 H755 T810 M813 M814 A815 A816 H831 L834 Y839 H841 T843 R847 R848 R896 D486 P487 C490 D492 I493 N494 D495 Y538 Y597 L639 S641 E671 M674 L675 R696 H698 T753 M756 M757 A758 A759 H774 L777 Y782 H784 T786 R790 R791 R839 3.1.13.-,3.1.26.- Q08162 RRKRLADGLSVTQKVFVRSRNGGATKIVREHYLRSDIPCLSRSCTKCPQIVVPDAQNELPKFILSDSPLELSAPIGKHYVVLDTNVVLQAIDLLENPNCFFDVIVPQIVLDEVRNKSYPVYTRLRTLCRDSDDHKRFIVFHNEFSEHTFVERLPNETINDRNNRAIRKTCQWYSEHLKPYDINVVLVTNDRLNREAATKEVESNIITKSLVQYIELLPNADDIRDSIPQDFTFPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLPRFSKPVLIVGQKNLNRAFNGDQVIVELLPQSEWKAVISDKQRRLLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCLPKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDINDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELTMGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNNESTETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKLTFVPTNSDKPRDVYVFDKVEVQVRSVMDPITSKRKAELLLK 5c0y A 2.10 BS01 NUC C 1 Y244 R461 V490 Y115 R332 V361 3.1.13.- Q12149 26222026 KRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMNIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIEKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRNIKNT 5c0y B 2.10 BS01 NUC D 1 L239 E240 H241 Y244 H291 F294 W299 Y315 H326 S327 L328 Q345 Y361 D365 R399 S413 I419 R461 V490 L113 E114 H115 Y118 H165 F168 W173 Y189 H200 S201 L202 Q219 Y235 D239 R273 S287 I293 R334 V363 3.1.13.- Q12149 26222026 KRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDENNPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMNIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRNIKNT 5c0y B 2.10 BS02 MG B 1 D238 L239 E240 Q255 D365 D112 L113 E114 Q129 D239 3.1.13.- Q12149 26222026 KRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDENNPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMNIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRNIKNT 5c1d A 2.05 BS01 III C 1 H496 H499 N557 H558 P559 T633 K634 Q839 F868 V895 H182 H185 N243 H244 P245 T319 K320 Q507 F536 V563 2.4.1.255 O15294 THADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMI 5c1m A 2.10 BS01 4VO A 1 H54 S55 Q124 D147 Y148 M151 V236 H297 V300 Y326 H3 S4 Q73 D96 Y97 M100 V185 H246 V249 Y275 P42866 GSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF 5c1m A 2.10 BS02 CLR A 1 T294 P295 Y299 I302 S317 C321 T243 P244 Y248 I251 S266 C270 P42866 GSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF 5c2t B 2.75 BS02 SF4 B 1 C182 C185 A186 C187 C188 A206 C249 P250 C150 C153 A154 C155 C156 A174 C217 P218 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 5c2t C 2.75 BS03 EPH D 1 M82 T85 I166 M49 T52 I133 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 5c2t F 2.75 BS02 SF4 F 1 C182 I183 C185 A186 C188 A206 C249 P250 L253 C150 I151 C153 A154 C156 A174 C217 P218 L221 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 5c2t F 2.75 BS04 4YP G 1 P193 S194 W197 P161 S162 W165 1.3.5.1 O44074 26198225 KRIKTFEIYRFNPEEPGAKPKLQKFDVDLDKCGTMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNIAGENTLACICNIDQNTSKTTKIYPLPHMFVIKDLVPDMNLFYAQYASIQPWLQKKTKINLGEKQQYQSIKEQEKLDGLYECILCACCSASCPSYWWNADKYLGPAVLMQAYRWIIDSRDDSAAERLARMQDGFSAFKCHTIMNCTKTCPKHLNPARAIGEIKMLLTKMKTKPAPLPTPANF 5c2t G 2.75 BS03 EPH H 1 M82 T85 L86 I128 L133 I166 M49 T52 L53 I95 L100 I133 P92506 26198225 EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT 5c5e A 2.82 BS01 III G 1 N213 L263 D267 A270 H271 E274 R278 N213 L263 D267 A270 H271 E274 R278 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c5e A 2.82 BS02 III H 1 E124 R127 T231 E235 M238 E255 R262 E124 R127 T231 E235 M238 E255 R262 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c5e A 2.82 BS03 52M A 1 S210 N213 Q214 D217 S210 N213 Q214 D217 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c5e B 2.82 BS01 III G 1 V230 T231 E235 H237 M238 M241 D242 L258 R262 V230 T231 E235 H237 M238 M241 D242 L258 R262 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c5e B 2.82 BS02 III H 1 N213 D217 L263 D267 A270 H271 E274 R278 N213 D217 L263 D267 A270 H271 E274 R278 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c5e B 2.82 BS03 52M A 1 K95 E96 K95 E96 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c5e B 2.82 BS04 52M B 1 L212 N213 I216 D267 L212 N213 I216 D267 Q79PF6 26200123 MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET 5c6q A 3.25 BS01 ZN A 1 H183 C186 H202 C204 H183 C186 H202 C204 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCT 5c6v A 3.10 BS01 III E 1 R67 Y68 K71 F74 K78 F104 L111 E114 N127 Q129 L130 R67 Y68 K71 F74 K78 F104 L111 E114 N127 Q129 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPPDIKTLFTDHTCT 5c6v B 3.10 BS01 III F 1 R67 K71 F74 K78 F104 L111 I115 L130 L150 R67 K71 F74 K78 F104 L111 I115 L130 L150 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPPDIKTLFTDHTCT 5c6v C 3.10 BS01 III G 1 Y68 K71 F74 K78 L111 I115 N127 Q129 L130 Y68 K71 F74 K78 L111 I115 N127 Q129 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPIKTLFTDHT 5c6v D 3.10 BS01 III H 1 Y68 K71 F74 K78 L111 L130 Y68 K71 F74 K78 L111 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRIKTLFTDHTC 5c7e A 3.10 BS01 III G 1 R67 Y68 M70 K71 F74 K78 L111 E114 Q129 L130 L150 R67 Y68 M70 K71 F74 K78 L111 E114 Q129 L130 L150 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCT 5c7e B 3.10 BS01 III H 1 K71 F74 K78 L111 N127 L130 K71 F74 K78 L111 N127 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCT 5c7e C 3.10 BS01 III I 1 R67 Y68 K71 K78 F104 L111 I115 Q129 R67 Y68 K71 K78 F104 L111 I115 Q129 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCTP 5c7e D 3.10 BS01 III J 1 R67 K71 F74 K78 N108 L111 I115 L130 R67 K71 F74 K78 N108 L111 I115 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCTP 5c7e E 3.10 BS01 III K 1 R67 K71 F74 K78 N108 L111 I115 L130 L150 R67 K71 F74 K78 N108 L111 I115 L130 L150 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCT 5c7e F 3.10 BS01 III L 1 R67 Y68 K71 F74 K78 N108 L111 I115 Q129 L130 R67 Y68 K71 F74 K78 N108 L111 I115 Q129 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCT 5c7f A 2.70 BS01 III E 1 R67 K71 F74 K78 N108 L111 Q129 L130 E146 R67 K71 F74 K78 N108 L111 Q129 L130 E146 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLIKTLFTDHTCT 5c7f A 2.70 BS02 ZN A 1 H183 H202 H183 H193 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLIKTLFTDHTCT 5c7f B 2.70 BS01 III F 1 K71 F74 K78 L111 I115 Q129 L130 K71 F74 K78 L111 I115 Q129 L130 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPIKTLFTDHTC 5c7f C 2.70 BS01 III G 1 R67 Y68 K71 F74 K78 L111 I115 Q129 L130 I142 R67 Y68 K71 F74 K78 L111 I115 Q129 L130 I142 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKIKTLFTDHTC 5c7f D 2.70 BS01 III H 1 R67 K71 F74 K78 N108 Q129 L130 L150 R67 K71 F74 K78 N108 Q129 L130 L150 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPDIKTLFTDHTC 5c7f D 2.70 BS02 ZN D 1 H183 C186 H202 T203 C204 H183 C186 H198 T199 C200 Q5NBT9 MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRHDRAKAVDILVKDLKVFSTFNEELYKEITQLLTLENFRENEQLSKYGDTKSARSIMLIELKKLIEANPLFREKLVFPTLKASRLRTLINQSLNWQHQLCKNPDIKTLFTDHTC 5cc9 A 1.20 BS01 NAP A 1 M16 G43 R44 H45 T46 L62 S63 S64 K76 G96 G97 R98 V99 Q102 T123 M16 G43 R44 H45 T46 L62 S63 S64 K76 G96 G97 R98 V99 Q102 T123 1.5.1.3 P0ABQ5 26147643 MISLIAALAVDRVIGMENAMPWNLPADFAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5cc9 A 1.20 BS02 DDF A 1 I5 A6 A7 D27 F28 W30 F31 K32 I50 L54 R57 I94 Y100 T113 I5 A6 A7 D27 F28 W30 F31 K32 I50 L54 R57 I94 Y100 T113 1.5.1.3 P0ABQ5 26147643 MISLIAALAVDRVIGMENAMPWNLPADFAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5ccc A 1.50 BS01 DDF A 1 I5 A6 A7 M20 D27 L28 W30 F31 K32 L54 R57 I94 Y100 T113 I5 A6 A7 M20 D27 L28 W30 F31 K32 L54 R57 I94 Y100 T113 1.5.1.3 P0ABQ5 26147643 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5ccc A 1.50 BS02 NAP A 1 M16 G43 R44 H45 T46 L62 S63 S64 Q65 K76 G96 G97 R98 V99 Q102 D122 T123 M16 G43 R44 H45 T46 L62 S63 S64 Q65 K76 G96 G97 R98 V99 Q102 D122 T123 1.5.1.3 P0ABQ5 26147643 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 5coq A 2.30 BS02 TCU A 1 G96 F97 M98 M103 F149 P156 A157 Y158 M161 K165 A198 M199 I202 G95 F96 M97 M102 F148 P155 A156 Y157 M160 K164 A197 M198 I201 1.3.1.9 M9TGV3 26147157 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIAGGEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5coq B 2.30 BS02 TCU B 1 G96 F97 M98 M103 F149 P156 A157 Y158 M161 K165 A198 M199 I202 I215 L218 G95 F96 M97 M102 F148 P155 A156 Y157 M160 K164 A197 M198 I201 I214 L217 1.3.1.9 M9TGV3 26147157 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIAGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5coq C 2.30 BS02 TCU C 1 G96 F97 M98 M103 F149 M155 P156 Y158 M161 K165 A198 M199 I202 G95 F96 M97 M102 F148 M154 P155 Y157 M160 K164 A197 M198 I201 1.3.1.9 M9TGV3 26147157 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5coq D 2.30 BS02 TCU D 1 G96 F97 M98 M103 F149 M155 P156 Y158 M161 K165 P193 A198 M199 I202 I215 G95 F96 M97 M102 F148 M154 P155 Y157 M160 K164 P192 A197 M198 I201 I208 1.3.1.9 M9TGV3 26147157 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIAEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 5cp3 A 1.99 BS01 YTZ A 1 N39 L41 R51 W94 Q101 N39 L41 R51 W94 Q101 DVVMTQTPITLSVTIGQPASISCKSSQSLLDSDGKTYLNWLLQRPGQSPKRLIYLVSKLDSRVPDRFTGSGAGTDFTLKISRVEAEDLGIYYCWQGTHFPQTFGGGTKLEIKRAEAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSETDQDSKDSTYSMSSTLTLTKDEYERHNTYTCEATHKTSTSPIVKSFNRNE 5cp3 A 1.99 BS02 CA A 1 D31 T97 D31 T97 DVVMTQTPITLSVTIGQPASISCKSSQSLLDSDGKTYLNWLLQRPGQSPKRLIYLVSKLDSRVPDRFTGSGAGTDFTLKISRVEAEDLGIYYCWQGTHFPQTFGGGTKLEIKRAEAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSETDQDSKDSTYSMSSTLTLTKDEYERHNTYTCEATHKTSTSPIVKSFNRNE 5cp3 H 1.99 BS01 YTZ A 1 H36 N38 A97 R98 Y99 G100 G101 W103 H36 N38 A97 R98 Y99 G100 G101 W103 DVQLRESGPDLVTPSQSLSLTCTVTGYSITSGYSWHWNRQFPGNKLEWMGYIHYSGSTNYNPSLRGRISITRDTSKNQFFLQLNSVTTEDTATYYCARYGGYWGQGTSVTVASAATTPPSVYPLAPGGGATNSMVTLGCLVKGYFPEPVTVTWNSGSLSGGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 5cp8 A 2.40 BS02 TCU A 1 G96 F97 M103 F149 P156 Y158 A198 M199 A215 L218 G94 F95 M101 F147 P154 Y156 A196 M197 A213 L216 1.3.1.9 M9TGV3 26147157 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQAQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL