3wpn A 2.80 BS01 B4S A 1 Y104 L292 L293 L295 I332 A334 Y352 A353 Y88 L232 L233 L235 I272 A274 Y292 A293 P52732 KGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGDKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTASSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKL 3wrn A 1.52 BS01 ZN A 1 E119 H127 H129 E114 H122 H124 P03134 25528417 YSDEVLGATNWLKEKSNQEVFSFVFKNENVQLNGKDIGWNSYKKELQEDELKSLQRGAETTWDQSEDMEWETTVDEMTKKQVFIFDSLVKKCLFEVLNTKNIFPGDVNWFVQHEWGKDQGWHCHVLIGGKDFSQAQGKWWRRQLNVYWSRWLVTACNVQLTPAERIKLREIAEDNEWVTLLTYKHKQTKKDYTKCVLFGNMIAYYFLTKKKISTSPPRDGGYFLSSDSGWKTNFLKEGERHLVSKLYT 3wxo A 2.12 BS02 NIZ A 1 W77 W78 K130 L291 I294 N295 G300 I301 W67 W68 K120 L281 I284 N285 G290 I291 1.11.1.21 Q31MN3 25303560 MHGGATTVNISTAEWWPKALNLDILSQHDRKTNPMGPDFNYQEEVKKLDVAALKQDLQALMTDSQDWWPADWGHYGGLMIRLTWHAAGTYRIADGRGGAGTGNQRFAPLNSWPDNTNLDKARRLLWPIKQKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHPEKDIYWGPEKEWVPPSTNPNSRYTGDRELENPLAAVTMGLIYVNPEGVDGNPDPLKTAHDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGNAALLGPEPEGADVEDQGLGWINKTQSGIGRNAVTSGLEGAWTPHPTQWDNGYFRMLLNYDWELKKSPAGAWQWEPINPREEDLPVDVEDPSIRRNLVMTDADMAMKMDPEYRKISERFYQDPAYFADVFARAWFKLTHRDMGPKARYIGPDVPQEDLIWQDPIPAGNRNYDVQAVKDRIAASGLSISELVSTAWDSARTYRNSDKRGGANGARIRLAPQKDWEGNEPDRLAKVLAVLEGIAAATGASVADVIVLAGNVGVEQAARAAGVEIVLPFAPGRGDATAEQTDTESFAVLEPIHDGYRNWLKQDYAATPEELLLDRTQLLGLTAPEMTVLIGGLRVLGTNHGGTKHGVFTDREGVLTNDFFVNLTDMNYLWKPAGKNLYEICDRKTNQVKWTATRVDLVFGSNSILRAYSELYAQDDNKEKFVRDFVAAWTKVMNADRFDLD 3wxo A 2.12 BS03 NIZ A 2 P123 D124 V193 T307 S308 P113 D114 V183 T297 S298 1.11.1.21 Q31MN3 25303560 MHGGATTVNISTAEWWPKALNLDILSQHDRKTNPMGPDFNYQEEVKKLDVAALKQDLQALMTDSQDWWPADWGHYGGLMIRLTWHAAGTYRIADGRGGAGTGNQRFAPLNSWPDNTNLDKARRLLWPIKQKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHPEKDIYWGPEKEWVPPSTNPNSRYTGDRELENPLAAVTMGLIYVNPEGVDGNPDPLKTAHDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGNAALLGPEPEGADVEDQGLGWINKTQSGIGRNAVTSGLEGAWTPHPTQWDNGYFRMLLNYDWELKKSPAGAWQWEPINPREEDLPVDVEDPSIRRNLVMTDADMAMKMDPEYRKISERFYQDPAYFADVFARAWFKLTHRDMGPKARYIGPDVPQEDLIWQDPIPAGNRNYDVQAVKDRIAASGLSISELVSTAWDSARTYRNSDKRGGANGARIRLAPQKDWEGNEPDRLAKVLAVLEGIAAATGASVADVIVLAGNVGVEQAARAAGVEIVLPFAPGRGDATAEQTDTESFAVLEPIHDGYRNWLKQDYAATPEELLLDRTQLLGLTAPEMTVLIGGLRVLGTNHGGTKHGVFTDREGVLTNDFFVNLTDMNYLWKPAGKNLYEICDRKTNQVKWTATRVDLVFGSNSILRAYSELYAQDDNKEKFVRDFVAAWTKVMNADRFDLD 3wxo A 2.12 BS04 NIZ A 3 N271 R367 N261 R357 1.11.1.21 Q31MN3 25303560 MHGGATTVNISTAEWWPKALNLDILSQHDRKTNPMGPDFNYQEEVKKLDVAALKQDLQALMTDSQDWWPADWGHYGGLMIRLTWHAAGTYRIADGRGGAGTGNQRFAPLNSWPDNTNLDKARRLLWPIKQKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHPEKDIYWGPEKEWVPPSTNPNSRYTGDRELENPLAAVTMGLIYVNPEGVDGNPDPLKTAHDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGNAALLGPEPEGADVEDQGLGWINKTQSGIGRNAVTSGLEGAWTPHPTQWDNGYFRMLLNYDWELKKSPAGAWQWEPINPREEDLPVDVEDPSIRRNLVMTDADMAMKMDPEYRKISERFYQDPAYFADVFARAWFKLTHRDMGPKARYIGPDVPQEDLIWQDPIPAGNRNYDVQAVKDRIAASGLSISELVSTAWDSARTYRNSDKRGGANGARIRLAPQKDWEGNEPDRLAKVLAVLEGIAAATGASVADVIVLAGNVGVEQAARAAGVEIVLPFAPGRGDATAEQTDTESFAVLEPIHDGYRNWLKQDYAATPEELLLDRTQLLGLTAPEMTVLIGGLRVLGTNHGGTKHGVFTDREGVLTNDFFVNLTDMNYLWKPAGKNLYEICDRKTNQVKWTATRVDLVFGSNSILRAYSELYAQDDNKEKFVRDFVAAWTKVMNADRFDLD 3x00 A 1.30 BS01 ZOF A 1 D23 L25 D27 Y43 W79 A86 S88 T90 W92 W108 L110 D128 D13 L15 D17 Y33 W69 A76 S78 T80 W82 W98 L100 D118 P22629 25560769 GSAEAGITGTWSDQLGDTFIVTAGADGALTGTYENAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNSKNAHSATTWSGQYVGGADAKINTQWLLTSGTTNANAWKSTLVGHDTFTKVK 3x00 A 1.30 BS02 ZOF D 1 W120 K121 W110 K111 P22629 25560769 GSAEAGITGTWSDQLGDTFIVTAGADGALTGTYENAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNSKNAHSATTWSGQYVGGADAKINTQWLLTSGTTNANAWKSTLVGHDTFTKVK 3x00 B 1.30 BS01 ZOF B 1 D23 L25 D27 Y43 W79 A86 S88 T90 W92 W108 L110 S112 L124 D128 D13 L15 D17 Y33 W69 A76 S78 T80 W82 W98 L100 S102 L114 D118 P22629 25560769 GSAEAGITGTWSDQLGDTFIVTAGADGALTGTYENAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNSKNAHSATTWSGQYVGGADAKINTQWLLTSGTTNANAWKSTLVGHDTFTKVK 3x00 C 1.30 BS01 ZOF C 1 D23 D27 W79 A86 S88 T90 W92 W108 L110 S112 L124 D128 D13 D17 W69 A76 S78 T80 W82 W98 L100 S102 L114 D118 P22629 25560769 GSAEAGITGTWSDQLGDTFIVTAGADGALTGTYENAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNSKNAHSATTWSGQYVGGADAKINTQWLLTSGTTNANAWKSTLVGHDTFTKVK 3x17 B 2.15 BS01 ZN B 1 C150 D166 H167 H193 C121 D137 H138 H164 3.2.1.4 W8PF21 25545469 LLQGAQILVNQVGYHPATPKQAVLALAPGTAAGIRPGWTPTLQIVRADDGQVVWEGTMAGPSEDRLVSGDTLYRADFTSLTAPGRYVAQVVGGPRSPEFAIGPVYRDVLYAAARSYYLQRCGVAIDDPITGVSHALDHHEDGYVLVDDPFYRAGTRLEATGGWHDAGDYGKYVTTTAVTAAQLLKAYELYPQAFADGQLHLPESGNGVPDILDEVRWGLEWLFRMQRPDGAVYHKLAGLRWPGMIRPEQDVQRRYVYRITTQDTAKAAAAWAMAARIFAPFDAAFARKALAAAEQAWRFLAASGPILDYPAEDNSGSGPYDDRDDADDRFWAAVELWVVTGRAEYHDYIARMARTGLPAYAPVSWVNPAALGYFDYVTLGQKGDPAIRARLVQRILEGARSVFQTYEQSGYGVPILAGSFHWGSNKEALAKGMLLLFAHHLEPRPEYERAALAQLDYVLGVNPLAKSYVTGLGSNPPRNPHHRLVKASGVMVPGLLVGGPNDHPQTKAIRPHMGPRGYADVTDSYETNEPAIDYNAPLVFVAAHFASL 3x17 B 2.15 BS02 CA B 1 D225 E232 S233 G234 N235 V237 D239 D242 D196 E203 S204 G205 N206 V208 D210 D213 3.2.1.4 W8PF21 25545469 LLQGAQILVNQVGYHPATPKQAVLALAPGTAAGIRPGWTPTLQIVRADDGQVVWEGTMAGPSEDRLVSGDTLYRADFTSLTAPGRYVAQVVGGPRSPEFAIGPVYRDVLYAAARSYYLQRCGVAIDDPITGVSHALDHHEDGYVLVDDPFYRAGTRLEATGGWHDAGDYGKYVTTTAVTAAQLLKAYELYPQAFADGQLHLPESGNGVPDILDEVRWGLEWLFRMQRPDGAVYHKLAGLRWPGMIRPEQDVQRRYVYRITTQDTAKAAAAWAMAARIFAPFDAAFARKALAAAEQAWRFLAASGPILDYPAEDNSGSGPYDDRDDADDRFWAAVELWVVTGRAEYHDYIARMARTGLPAYAPVSWVNPAALGYFDYVTLGQKGDPAIRARLVQRILEGARSVFQTYEQSGYGVPILAGSFHWGSNKEALAKGMLLLFAHHLEPRPEYERAALAQLDYVLGVNPLAKSYVTGLGSNPPRNPHHRLVKASGVMVPGLLVGGPNDHPQTKAIRPHMGPRGYADVTDSYETNEPAIDYNAPLVFVAAHFASL 3x17 B 2.15 BS03 CA B 2 D351 D353 D356 D357 V395 D322 D324 D327 D328 V366 3.2.1.4 W8PF21 25545469 LLQGAQILVNQVGYHPATPKQAVLALAPGTAAGIRPGWTPTLQIVRADDGQVVWEGTMAGPSEDRLVSGDTLYRADFTSLTAPGRYVAQVVGGPRSPEFAIGPVYRDVLYAAARSYYLQRCGVAIDDPITGVSHALDHHEDGYVLVDDPFYRAGTRLEATGGWHDAGDYGKYVTTTAVTAAQLLKAYELYPQAFADGQLHLPESGNGVPDILDEVRWGLEWLFRMQRPDGAVYHKLAGLRWPGMIRPEQDVQRRYVYRITTQDTAKAAAAWAMAARIFAPFDAAFARKALAAAEQAWRFLAASGPILDYPAEDNSGSGPYDDRDDADDRFWAAVELWVVTGRAEYHDYIARMARTGLPAYAPVSWVNPAALGYFDYVTLGQKGDPAIRARLVQRILEGARSVFQTYEQSGYGVPILAGSFHWGSNKEALAKGMLLLFAHHLEPRPEYERAALAQLDYVLGVNPLAKSYVTGLGSNPPRNPHHRLVKASGVMVPGLLVGGPNDHPQTKAIRPHMGPRGYADVTDSYETNEPAIDYNAPLVFVAAHFASL 3x17 A 2.15 BS02 CA A 1 D225 E232 S233 G234 N235 V237 P238 D239 D242 D196 E203 S204 G205 N206 V208 P209 D210 D213 3.2.1.4 W8PF21 25545469 LLQGAQILVNQVGYHPATPKQAVLALAPGTAAGIRPGWTPTLQIVRADDGQVVWEGTMAGPSEDRLVSGDTLYRADFTSLTAPGRYVAQVVGGPRSPEFAIGPVYRDVLYAAARSYYLQRCGVAIDDPITGVSHALDHHEDGYVLVDDPFYRAGTRLEATGGWHDAGDYGKYVTTTAVTAAQLLKAYELYPQAFADGQLHLPESGNGVPDILDEVRWGLEWLFRMQRPDGAVYHKLAGLRWPGMIRPEQDVQRRYVYRITTQDTAKAAAAWAMAARIFAPFDAAFARKALAAAEQAWRFLAASGPILDYPAEDNSGSGPYDDRDDADDRFWAAVELWVVTGRAEYHDYIARMARTGLPAYAPVSWVNPAALGYFDYVTLGQKGDPAIRARLVQRILEGARSVFQTYEQSGYGVPILAGSFHWGSNKEALAKGMLLLFAHHLEPRPEYERAALAQLDYVLGVNPLAKSYVTGLGSNPPRNPHHRLVKASGVMVPGLLVGGPNDHPQTKAIRPHMGPRGYADVTDSYETNEPAIDYNAPLVFVAAHFASL 3x1n A 1.55 BS01 CU A 1 H95 H143 M148 H78 H126 M131 A4IL26 25563214 IAAHKGVNQAPVPLKMERVGPHDVHIEMTAQITDIEIDKGKIYKAWTFNGQAPGPLVVVNEGDTIHFTLKNMDPVVPHSMDFHAVHASPSKDFIDVMPNKSGTFTYPANKPGVFMYHAGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYVLIQNEWYKYNDMNDFQNGVPSYVVFSSKALKPGDPNTNGDTFTLKEKPLLAKVGEKIRLYINNVGPNEVSSFHVVGTVFDDVYLDGNPNNHLQGMQTVMLPASGGAVVEFTVTRPGTYPIVTHQFNHAQKGAVAMLKVTETGED 4c5a A 1.65 BS01 III C 1 M1 T2 K4 R31 G34 I35 D36 Y38 M1 T2 K4 R31 G34 I35 D36 Y38 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5a A 1.65 BS02 ADP A 1 K97 I142 K144 E148 G149 S150 S151 M154 E180 K181 W182 L183 E187 F209 Y210 K215 D257 M259 L269 E270 K97 I142 K144 E148 G149 S150 S151 M154 E180 K181 W182 L183 E187 F209 Y210 K215 D257 M259 L269 E270 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5a A 1.65 BS03 DS0 A 1 E15 H63 G149 S150 K215 Y216 R255 D257 E270 N272 P275 G276 E15 H63 G149 S150 K215 Y216 R255 D257 E270 N272 P275 G276 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5a A 1.65 BS04 MG A 1 G149 E270 N272 G149 E270 N272 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5b A 1.50 BS02 DAL A 1 E15 H63 S150 Y216 R255 G276 E15 H63 S150 Y216 R255 G276 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5b A 1.50 BS03 DAL A 2 K215 Y216 R255 G276 S281 L282 K215 Y216 R255 G276 S281 L282 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4c5b A 1.50 BS04 CO3 A 1 G149 S150 K215 R255 D257 E270 N272 G149 S150 K215 R255 D257 E270 N272 6.3.2.4 C4ZRI7 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 4ckq A 1.40 BS01 III C 1 E136 Y139 E142 F172 Y200 E225 Y227 W264 E140 Y143 E146 F176 Y204 E229 Y231 W268 3.2.1.8 C7HEF6 HMASATINLSAEKQVIRGFGGMNHPVWISDLTPQQRDTAFGNGEGQLGFTILRIHVDENRNNWSKEVATARRAIELGAIVSASPWNPPSNMVETFTRNGVPNQKRLRYDKYGDYVQHLNDFVAYMKSNGVDLYAISVQNEPDYAHEWTWWTPQEMLRFMRDYAGQINCRVMAPESFQYLKNMSDPILNDPQALANLDILGAHFYGTTVNNMPYPLFEQKGAGKELWMTEVYVPNSDSNSADRWPEALEVAHNMHNALVEGNFQAYVWWYIRRSYGPMKEDGTISKRGYMMAHYSKFVRPGYVRVDATKNPTYNVYLSACKNKKDNSVVAVVINKSTEAKTINISVPGTSIRKWERYVTTGSKNLRKESDINASGTTFQVTLEPQSVTTFV 4cl6 A 2.41 BS01 7SB A 1 H70 F71 G79 F113 G115 H69 F70 G78 F112 G114 4.2.1.59,5.3.3.14,4.2.1.60 O33877 TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRTINLVLAIADGTVSVDGREIYSAEGLRVGLFTSTDSF 4cl6 A 2.41 BS02 7SB B 1 A26 Q27 L28 W87 Q88 G91 F92 G103 R104 A105 F171 A25 Q26 L27 W86 Q87 G90 F91 G102 R103 A104 F168 4.2.1.59,5.3.3.14,4.2.1.60 O33877 TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRTINLVLAIADGTVSVDGREIYSAEGLRVGLFTSTDSF 4cl6 B 2.41 BS02 7SB B 1 H70 F71 G79 G115 H69 F70 G78 G114 4.2.1.59,5.3.3.14,4.2.1.60 O33877 TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRTINRSLVLAIADGTVSVDGREIYSAEGLRVGLFTSTDSF 4cl8 A 2.20 BS01 OZJ A 1 R14 S95 F97 C168 Y174 G205 V206 L209 P210 R13 S94 F96 C151 Y157 G188 V189 L192 P193 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cl8 A 2.20 BS02 NAP A 1 G10 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 Y174 K178 P204 G205 V206 S207 L208 G9 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L142 C143 Y157 K161 P187 G188 V189 S190 L191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cl8 B 2.20 BS01 OZJ B 1 R14 S95 F97 C168 Y174 G205 V206 P210 R13 S94 F96 C151 Y157 G188 V189 P193 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cl8 C 2.20 BS01 OZJ C 1 R14 S95 F97 D161 C168 Y174 G205 V206 P210 R13 S94 F96 D141 C148 Y154 G185 V186 P190 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cld A 1.77 BS02 JUO A 1 R14 F97 D161 Y174 V206 L209 P210 W221 R13 F96 D144 Y157 V189 L192 P193 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cle A 1.80 BS01 NAP A 1 R14 I15 H33 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 K178 P204 G205 S207 R13 I14 H32 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L143 C144 D145 K162 P188 G189 S191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cle A 1.80 BS03 JR2 A 2 F97 D161 M163 C168 G205 L209 W221 F96 D145 M147 C152 G189 L193 W205 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cle D 1.80 BS03 JR2 D 2 F97 D161 M163 C168 F171 L209 W221 F96 D143 M145 C150 F153 L191 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVNGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clh A 1.85 BS03 W8G A 2 F97 D161 M163 C168 F171 G205 L209 P210 W221 F96 D145 M147 C152 F155 G189 L193 P194 W205 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clh B 1.85 BS03 W8G B 2 F97 D161 M163 C168 F171 G205 L209 W221 F96 D144 M146 C151 F154 G188 L192 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clh C 1.85 BS03 W8G C 2 F97 D161 M163 C168 F171 G205 L209 M213 W221 F96 D144 M146 C151 F154 G188 L192 M196 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clh D 1.85 BS03 W8G D 2 F97 D161 M163 C168 G205 V206 L209 W221 F96 D143 M145 C150 G187 V188 L191 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clo A 1.88 BS02 XP0 A 1 S95 F97 Y174 L209 P210 M213 W221 S94 F96 Y157 L192 P193 M196 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clo B 1.88 BS02 XP0 B 1 S95 F97 Y174 L209 P210 W221 S94 F96 Y158 L193 P194 W205 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clo D 1.88 BS02 XP0 D 1 S95 F97 Y174 V206 L209 P210 M213 W221 S94 F96 Y155 V187 L190 P191 M194 W202 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4clx A 1.85 BS01 NAP A 1 R14 I15 Y34 H35 N36 S37 A61 D62 L63 T64 N93 A94 S95 T126 L159 C160 D161 K178 P204 G205 V206 S207 L208 R13 I14 Y33 H34 N35 S36 A60 D61 L62 T63 N92 A93 S94 T117 L142 C143 D144 K161 P187 G188 V189 S190 L191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm1 A 1.90 BS02 IQW A 1 S95 F97 D161 Y174 L209 P210 W221 S94 F96 D144 Y157 L192 P193 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm1 C 1.90 BS02 IQW C 1 S95 F97 D161 Y174 G205 L209 P210 M213 W221 S94 F96 D143 Y156 G187 L191 P192 M195 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm1 D 1.90 BS02 IQW D 1 S95 F97 D161 Y174 L209 P210 M213 W221 S94 F96 D143 Y156 L191 P192 M195 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm3 C 1.95 BS02 KP2 C 1 S95 F97 Y174 L209 P210 M213 S94 F96 Y155 L190 P191 M194 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm5 A 1.99 BS02 NWJ A 1 R14 S95 F97 C168 Y174 P210 R13 S94 F96 C150 Y156 P192 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm5 B 1.99 BS02 NWJ B 1 S95 F97 P167 C168 Y174 G205 L209 P210 M213 W221 S94 F96 P149 C150 Y156 G187 L191 P192 M195 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm5 C 1.99 BS02 NWJ C 1 R14 S95 F97 C168 Y174 G205 P210 R13 S94 F96 C149 Y155 G186 P191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm7 A 1.90 BS02 H0V A 1 R14 S95 F97 Y174 G205 V206 L208 W221 R13 S94 F96 Y158 G189 V190 L192 W205 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQNGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm7 C 1.90 BS02 H0V C 1 R14 S95 F97 Y174 G205 V206 L208 P210 W221 R13 S94 F96 Y157 G188 V189 L191 P193 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm7 D 1.90 BS02 H0V D 1 R14 S95 F97 C168 Y174 G205 V206 L208 P210 W221 R13 S94 F96 C150 Y156 G187 V188 L190 P192 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm8 C 1.90 BS02 IZ9 C 1 R14 S95 F97 D161 M163 Q166 C168 Y174 P210 W221 R13 S94 F96 D142 M144 Q147 C149 Y155 P191 W202 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cm9 A 1.90 BS02 YGL A 1 R14 S95 F97 D161 M163 C168 Y174 G205 L209 P210 M213 R13 S94 F96 D142 M144 C149 Y155 G186 L190 P191 M194 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cma A 1.85 BS02 M2N A 1 R14 S95 F97 D161 M163 C168 Y174 G205 V206 L209 R13 S94 F96 D143 M145 C150 Y156 G187 V188 L191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cma B 1.85 BS02 M2N B 1 S95 F97 D161 M163 C168 Y174 G205 V206 L209 S94 F96 D143 M145 C150 Y156 G187 V188 L191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cma D 1.85 BS02 M2N D 1 S95 F97 D161 M163 C168 Y174 G205 L209 P210 S94 F96 D143 M145 C150 Y156 G187 L191 P192 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmb C 1.96 BS02 UEN C 1 R14 S95 F97 Y174 V206 L209 M213 R13 S94 F96 Y155 V187 L190 M194 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmc D 1.85 BS02 VS8 D 1 R14 S95 F97 D161 C168 Y174 G205 L209 P210 W221 R13 S94 F96 D144 C151 Y157 G188 L192 P193 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQNGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cme A 1.85 BS02 KTZ A 1 R14 S95 F97 M163 C168 Y174 G205 L209 P210 R13 S94 F96 M144 C149 Y155 G186 L190 P191 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cme B 1.85 BS02 KTZ B 1 R14 S95 F97 M163 C168 Y174 G205 L209 R13 S94 F96 M144 C149 Y155 G186 L190 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmg A 2.00 BS02 UHX A 1 R14 S95 F97 D161 M163 C168 Y174 G205 V206 L209 P210 M213 W221 R13 S94 F96 D143 M145 C150 Y156 G187 V188 L191 P192 M195 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmg B 2.00 BS02 UHX B 1 S95 F97 M163 C168 Y174 V206 L209 M213 W221 S94 F96 M146 C151 Y157 V189 L192 M196 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmg C 2.00 BS02 UHX C 1 R14 S95 F97 D161 M163 C168 Y174 G205 V206 S207 L209 M213 W221 R13 S94 F96 D143 M145 C150 Y156 G187 V188 S189 L191 M195 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmi A 1.90 BS02 M4V A 1 S95 F97 M163 Q166 C168 Y174 G205 L209 P210 W221 S94 F96 M145 Q148 C150 Y156 G187 L191 P192 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmi B 1.90 BS02 M4V B 1 S95 F97 D161 M163 Q166 C168 Y174 L209 P210 W221 S94 F96 D144 M146 Q149 C151 Y157 L192 P193 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmi C 1.90 BS02 M4V C 1 R14 S95 F97 M163 Q166 C168 Y174 G205 P210 W221 R13 S94 F96 M145 Q148 C150 Y156 G187 P192 W203 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmj B 2.20 BS02 UIH B 1 R14 S95 F97 D161 M163 Q166 Y174 V206 L209 P210 R13 S94 F96 D144 M146 Q149 Y157 V189 L192 P193 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQKSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmj C 2.20 BS02 UIH C 1 S95 F97 D161 M163 Q166 C168 Y174 P210 M213 W221 S94 F96 D144 M146 Q149 C151 Y157 P193 M196 W204 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmj D 2.20 BS02 UIH D 1 S95 F97 D161 M163 C168 Y174 L209 M213 W221 S94 F96 D142 M144 C149 Y155 L190 M194 W202 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmk A 2.00 BS02 FQW A 1 R14 S95 F97 D161 M163 C168 F171 Y174 G205 V206 P210 R13 S94 F96 D143 M145 C150 F153 Y156 G187 V188 P192 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4cmk D 2.00 BS02 FQW D 1 R14 S95 F97 D161 M163 C168 F171 Y174 G205 P210 M213 R13 S94 F96 D143 M145 C150 F153 Y156 G187 P192 M195 1.5.1.33 O76290 25007262 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 4ct9 A 2.14 BS01 AMP A 1 L13 T18 L19 D20 T21 N22 G152 P153 L13 T18 L19 D20 T21 N22 G152 P153 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4d5e A 1.43 BS01 FAD A 1 H153 G213 G214 G215 R218 S219 T239 S240 T241 A257 G258 F259 C260 G261 G279 S280 R281 S283 W285 G286 D302 T303 D304 V307 A320 D321 A322 I398 F406 S420 M421 G424 H152 G212 G213 G214 R217 S218 T238 S239 T240 A256 G257 F258 C259 G260 G278 S279 R280 S282 W284 G285 D301 T302 D303 V306 A319 D320 A321 I397 F405 S419 M420 G423 3.7.1.11 P0CH62 AIKRGADLIVEALEEYGTEQVVGFIGHTSHFVADAFSKSHLGKRVINPATELGGAWMVNGYNYVKDRSAAVGAWHCVGNLLLHAAMQEARTGRIPAVHIGLNSDGRLAGRSEAAQQVPWQSFTPIARSTQRVERLDKVGEAIHEAFRVAEGHPAGPAYVDIPFDLTADQIDDKALVPRGATRAKSVLHAPNEDVREAAAQLVAAKNPVILAGGGVARSGGSEALLKLAEMVGVPVVTTSTGAGVFPETHALAMGSAGFCGWKSANDMMAAADFVLVLGSRLSDWGIAQGYITKMPKFVHVDTDPAVLGTFYFPLLSVVADAKTFMEQLIEVLPGTSGFKAVRYQERENFRQATEFRAAWDGWVREQESGDGMPASMFRAMAEVRKVQRPEDIIVTDIGNHTLPMFGGAILQRPRRLVTSMAEGILGCGFPMALGAQLAEPNSRVFLGTGDGALYYHFNEFRVAVEHKLPVITMVFTNESYGANWTLMNHQFGQNNWTEFMNPDWVGIAKAFGAYGESVRETGDIAGALQRAIDSGKPALIEIPVSKTQGLASDPVGGVGPNLLLKGREIPVDTGGSMYPGENLLHL 4d5e B 1.43 BS04 MG B 1 R148 R183 A184 R147 R182 A183 3.7.1.11 P0CH62 AIKRGADLIVEALEEYGTEQVVGFIGHTSHFVADAFSKSHLGKRVINPATELGGAWMVNGYNYVKDRSAAVGAWHCVGNLLLHAAMQEARTGRIPAVHIGLNSDGRLAGRSEAAQQVPWQSFTPIARSTQRVERLDKVGEAIHEAFRVAEGHPAGPAYVDIPFDLTADQIDDKALVPRGATRAKSVLHAPNEDVREAAAQLVAAKNPVILAGGGVARSGGSEALLKLAEMVGVPVVTTSTGAGVFPETHALAMGSAGFCGWKSANDMMAAADFVLVLGSRLSDWGIAQGYITKMPKFVHVDTDPAVLGTFYFPLLSVVADAKTFMEQLIEVLPGTSGFKAVRYQERENFRQATEFRAAWDGWVREQESGDGMPASMFRAMAEVRKVQRPEDIIVTDIGNHTLPMFGGAILQRPRRLVTSMAEGILGCGFPMALGAQLAEPNSRVFLGTGDGALYYHFNEFRVAVEHKLPVITMVFTNESYGANWTLMNHQFGQNNWTEFMNPDWVGIAKAFGAYGESVRETGDIAGALQRAIDSGKPALIEIPVSKTQGLASDPVGGVGPNLLLKGREIPVDTGGSMYPGENLLHLK 4d5g A 2.00 BS01 FAD A 1 H153 G213 G214 G215 R218 S219 T239 S240 T241 A257 G258 F259 C260 G261 G279 S280 R281 S283 W285 G286 D302 T303 D304 V307 A320 D321 A322 F406 S420 M421 A422 G424 H152 G212 G213 G214 R217 S218 T238 S239 T240 A256 G257 F258 C259 G260 G278 S279 R280 S282 W284 G285 D301 T302 D303 V306 A319 D320 A321 F405 S419 M420 A421 G423 3.7.1.11 P0CH62 AIKRGADLIVEALEEYGTEQVVGFIGATSHFVADAFSKSHLGKRVINPATELGGAWMVNGYNYVKDRSAAVGAWHCVGNLLLHAAMQEARTGRIPAVHIGLNSDGRLAGRSEAAQQVPWQSFTPIARSTQRVERLDKVGEAIHEAFRVAEGHPAGPAYVDIPFDLTADQIDDKALVPRGATRAKSVLHAPNEDVREAAAQLVAAKNPVILAGGGVARSGGSEALLKLAEMVGVPVVTTSTGAGVFPETHALAMGSAGFCGWKSANDMMAAADFVLVLGSRLSDWGIAQGYITKMPKFVHVDTDPAVLGTFYFPLLSVVADAKTFMEQLIEVLPGTSGFKAVRYQERENFRQATEFRAAWDGWVREQESGDGMPASMFRAMAEVRKVQRPEDIIVTDIGNHTLPMFGGAILQRPRRLVTSMAEGILGCGFPMALGAQLAEPNSRVFLGTGDGALYYHFNEFRVAVEHKLPVITMVFTNESYGANWTLMNHQFGQNNWTEFMNPDWVGIAKAFGAYGESVRETGDIAGALQRAIDSGKPALIEIPVSKTQGLASDPVGGVGPNLLLKGREIPVDTGGSMYPGENLLHL 4n56 A 2.20 BS01 NUC B 1 R487 T506 K508 T509 S513 T514 S515 A516 R536 K540 L541 Y545 R573 Q582 N583 I584 P585 V586 R587 V783 H784 R194 T213 K215 T216 S220 T221 S222 A223 R243 K247 L248 Y252 R280 Q289 N290 I291 P292 V293 R294 V445 H446 2.7.7.7 P19821 25537790 LEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETAAKTINFGVLYGFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 4n56 A 2.20 BS02 NUC C 1 N483 N485 S486 Q489 S543 T544 A568 T569 A570 T571 R573 S575 S576 S577 D578 N580 F667 Y671 R728 R746 M747 N750 Q754 N190 N192 S193 Q196 S250 T251 A275 T276 A277 T278 R280 S282 S283 S284 D285 N287 F356 Y360 R390 R408 M409 N412 Q416 2.7.7.7 P19821 25537790 LEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETAAKTINFGVLYGFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 4n5s A 1.67 BS01 NUC B 1 R487 T506 K508 T509 S513 T514 S515 A516 R536 K540 Y545 R573 Q582 N583 I584 P585 V586 R587 R660 V783 H784 R198 T217 K219 T220 S224 T225 S226 A227 R247 K251 Y256 R284 Q293 N294 I295 P296 V297 R298 R371 V494 H495 2.7.7.7 P19821 25537790 SPKALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAK 4n5s A 1.67 BS02 NUC C 1 N483 N485 S486 Q489 S543 T544 T569 A570 T571 R573 S575 S576 S577 D578 N580 T664 G668 Y671 M673 S674 R677 R728 R746 M747 N750 Q754 N194 N196 S197 Q200 S254 T255 T280 A281 T282 R284 S286 S287 S288 D289 N291 T375 G379 Y382 M384 S385 R388 R439 R457 M458 N461 Q465 2.7.7.7 P19821 25537790 SPKALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAK 4n5s A 1.67 BS05 DCT A 1 R573 D610 Y611 S612 Q613 I614 E615 H639 R659 K663 F667 D785 R284 D321 Y322 S323 Q324 I325 E326 H350 R370 K374 F378 D496 2.7.7.7 P19821 25537790 SPKALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAK 4nnl A 1.50 BS01 III C 1 I28 L29 G30 F31 S32 I33 G34 Q39 Q43 N44 P45 T58 R59 H90 L97 T98 I19 L20 G21 F22 S23 I24 G25 Q30 Q34 N35 P36 T49 R50 H81 L88 T89 O14907 TAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 4nnm A 1.60 BS01 III C 1 I29 L30 G31 F32 S33 I34 G35 G36 Q40 Q44 N45 T59 R60 H91 R95 L98 T99 I19 L20 G21 F22 S23 I24 G25 G26 Q30 Q34 N35 T49 R50 H81 R85 L88 T89 O14907 TAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ 4nr1 A 2.68 BS01 III S 1 Y93 Y102 H199 D201 E202 Q203 R238 Y276 W296 I306 Y308 Q314 A317 I318 N321 Y79 Y88 H185 D187 E188 Q189 R224 Y262 W282 I292 Y294 Q300 A303 I304 N307 1.14.11.30 Q9NWT6 EPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN 4nv7 A 2.02 BS01 COA A 1 W42 Y72 C73 W100 S111 H112 F130 G131 G132 L133 E152 I169 F204 I209 R218 A220 R222 H229 W38 Y68 C69 W96 S105 H106 F124 G125 G126 L127 E146 I163 F198 I203 R212 A214 R216 H223 2.3.1.5 Q98D42 PPFDLDAYLARIGYTGPRNASLDTLKALHFAHPQAIPWENIDPFLGRPVRLDLAALQDKIVLGGRGGYCFEHNLLFMHALKALGFEVGGLAARVLWGQDAITARSHMLLRVELDGRTYIADVGFGGLTLTAPLLLEPGREQKTPHEPFRIVEADDHFRLQAAIGGDWRSLYRFDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSIHHLGGRTEQTEIATAADLADTLQGLLGIIIPDRTAFEAKVRETKIV 4nv7 B 2.02 BS01 COA B 1 W42 Y72 C73 W100 S111 H112 F130 G131 G132 I169 F204 I209 A220 R222 R225 H229 W38 Y68 C69 W96 S107 H108 F126 G127 G128 I165 F200 I205 A216 R218 R221 H225 2.3.1.5 Q98D42 PPFDLDAYLARIGYTGPRNASLDTLKALHFAHPQAIPWENIDPFLGRPVRLDLAALQDKIVLGGRGGYCFEHNLLFMHALKALGFEVGGLAARVLWGQSEDAITARSHMLLRVELDGRTYIADVGFGGLTLTAPLLLEPGREQKTPHEPFRIVEADDHFRLQAAIGGDWRSLYRFDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSIHHLGGRTEQTEIATAADLADTLQGLLGIIIPDRTAFEAKVRETKIV 4o1e A 1.61 BS01 C2F A 1 E7 K8 I13 D76 N97 I121 D161 G196 K208 I227 D229 N232 E10 K11 I16 D79 N100 I124 D164 G199 K211 I230 D232 N235 B8FW00 GSHMLIIIGEKINGTIPSVKKAIEAKDEKLIRDLALRQSEAGADYIDVCASTSPELEVETLQWLMDIVQEATDTPLCIDSPNPRAIQQVLLYAKRPGLINSVSLEGDKCEVIFPLIQGTSWQVIALTCDNSGIPQDVQSRVEIAQALVEKAQSYDIAQERIHIDPLVIALSADNGALLKFAEATRQIKANYPMINVTSGLSNISFGMPLRKVVNQNFLTLAMFAGMDSAILDPLNRDLLAALLATEALLGRDKHCRNFANAYRKNKIGPLK 4ofg A 2.00 BS01 PCG A 1 I465 L472 R473 F481 G482 E483 R484 A485 R492 T493 A494 Q532 I65 L72 R73 F81 G82 E83 R84 A85 R92 T93 A94 Q132 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ofg A 2.00 BS02 N2P A 1 D479 Y480 R528 Q532 D79 Y80 R128 Q132 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ofg A 2.00 BS03 N2P A 2 L475 D479 L75 D79 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ofg A 2.00 BS04 N2P A 3 A402 D405 K409 E432 A2 D5 K9 E32 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ofg A 2.00 BS05 N2P A 4 R528 M531 R128 M131 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ofg A 2.00 BS06 N2P A 5 L486 L487 K510 L514 Q518 L86 L87 K110 L114 Q118 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ofg A 2.00 BS07 N2P A 6 S511 Q515 S111 Q115 2.7.11.12 Q8MMZ4 DASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIVKNKKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQGPMLAHLEERIKMQDTKVEMDELE 4ogb A 2.03 BS01 2SR A 1 H160 M273 L319 I336 F340 M357 S368 Q369 F372 I376 H78 M191 L237 I254 F258 M275 S286 Q287 F290 I294 3.1.4.53 Q08499 GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI 4ogb B 2.03 BS01 2SR B 1 H160 M273 L319 M357 S368 Q369 F372 H69 M182 L228 M266 S277 Q278 F281 3.1.4.53 Q08499 LAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ 4ogu A 2.10 BS03 IPE A 1 G56 K57 R60 Q96 R113 T201 Y204 Q240 D243 G45 K46 R49 Q85 R102 T190 Y193 Q229 D232 2.5.1.10,2.5.1.1 P14324 DVYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNTIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFAQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 4ohn A 1.37 BS01 HIS A 1 D46 F49 W87 N104 G105 Y106 S107 R112 Q151 S154 S155 D200 D20 F23 W61 N78 G79 Y80 S81 R86 Q125 S128 S129 D174 TSGDNWSKYQSNKSITIGFDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLIWNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADFEANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYNVFTVGLETEAFAVGSRKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATK 4oic A 2.00 BS01 A8S A 1 K74 F76 V98 A104 S107 F123 H130 Y135 F180 T181 V184 N188 K63 F65 V87 A93 S96 F112 H119 Y124 F162 T163 V166 N170 Q5Z8S0 24743650 AHVERALREGLTEEERAALEPAVMAHHTFPAATCTSLVTQRVAAPVRAVWPIVRSFGNPQRYKHFVRTCALAAGDGASVGSVREVTVVSGLPASTSTERLEMLDDDRHIISFRVVGGQHRLRNYRSVTSVTEFQPPPPYCVVVESYVVDVPDGNTAEDTRMFTDTVVKLNLQMLAAVAEDSS 4oic B 2.00 BS01 MN B 1 D205 D386 D448 D66 D242 D293 3.1.3.16 Q0JLP9 24743650 SVFAVECVPLWGHKSICGRRPEMEDAVVAVSRFFDIPLWMLTGNSVVDGLDPMSFRLPAHFFGVYDGHGGAQVANYCRERLHAALVEELSRIEGSVSGANLGSVEFKKKWEQAFVDCFSRVDEEVGGNAVAPETVGSTAVVAVICSSHIIVANCGDSRAVLCRGKQPVPLSVDHKPNREDEYARIEAEGGKVIQWNGYRVFGVLAMSRSIGDRYLKPWIIPVPEITIVPRAKDDECLVLASDGLWDVMSNEEVCDVARKRILLWHKKNGSSDPAAEAAAECLSKLALQKGSKDNISVIVVDLKAH 4oic B 2.00 BS02 MN B 2 D205 G206 D66 G67 3.1.3.16 Q0JLP9 24743650 SVFAVECVPLWGHKSICGRRPEMEDAVVAVSRFFDIPLWMLTGNSVVDGLDPMSFRLPAHFFGVYDGHGGAQVANYCRERLHAALVEELSRIEGSVSGANLGSVEFKKKWEQAFVDCFSRVDEEVGGNAVAPETVGSTAVVAVICSSHIIVANCGDSRAVLCRGKQPVPLSVDHKPNREDEYARIEAEGGKVIQWNGYRVFGVLAMSRSIGDRYLKPWIIPVPEITIVPRAKDDECLVLASDGLWDVMSNEEVCDVARKRILLWHKKNGSSDPAAEAAAECLSKLALQKGSKDNISVIVVDLKAH 4oic B 2.00 BS03 MN B 3 D386 D390 D242 D246 3.1.3.16 Q0JLP9 24743650 SVFAVECVPLWGHKSICGRRPEMEDAVVAVSRFFDIPLWMLTGNSVVDGLDPMSFRLPAHFFGVYDGHGGAQVANYCRERLHAALVEELSRIEGSVSGANLGSVEFKKKWEQAFVDCFSRVDEEVGGNAVAPETVGSTAVVAVICSSHIIVANCGDSRAVLCRGKQPVPLSVDHKPNREDEYARIEAEGGKVIQWNGYRVFGVLAMSRSIGDRYLKPWIIPVPEITIVPRAKDDECLVLASDGLWDVMSNEEVCDVARKRILLWHKKNGSSDPAAEAAAECLSKLALQKGSKDNISVIVVDLKAH 4oic B 2.00 BS04 MN B 4 R322 D324 R178 D180 3.1.3.16 Q0JLP9 24743650 SVFAVECVPLWGHKSICGRRPEMEDAVVAVSRFFDIPLWMLTGNSVVDGLDPMSFRLPAHFFGVYDGHGGAQVANYCRERLHAALVEELSRIEGSVSGANLGSVEFKKKWEQAFVDCFSRVDEEVGGNAVAPETVGSTAVVAVICSSHIIVANCGDSRAVLCRGKQPVPLSVDHKPNREDEYARIEAEGGKVIQWNGYRVFGVLAMSRSIGDRYLKPWIIPVPEITIVPRAKDDECLVLASDGLWDVMSNEEVCDVARKRILLWHKKNGSSDPAAEAAAECLSKLALQKGSKDNISVIVVDLKAH 4pj3 A 2.30 BS01 ANP A 1 I800 Q801 F802 Q806 P825 G826 G828 K829 T830 D831 R1138 L1157 I759 Q760 F761 Q765 P784 G785 G787 K788 T789 D790 R1092 L1111 O60306 NAEFVTQLACKYWAPHIKKKSPFDIKVIEDIYEKEIVKSRFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQ 4pj3 A 2.30 BS02 MG A 1 T830 Q861 T789 Q820 O60306 NAEFVTQLACKYWAPHIKKKSPFDIKVIEDIYEKEIVKSRFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQ 4pry A 1.70 BS01 III B 1 S63 R64 H121 G122 Q161 C163 Y204 S205 W206 R207 N208 S209 W214 S249 F250 S35 R36 H93 G94 Q133 C135 Y174 S175 W176 R177 N178 S179 W184 S219 F220 3.4.22.56 P42574 25079698 SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHQL 4prz A 2.12 BS01 III B 1 R260 S316 H317 G318 Q358 A359 C360 S411 Y412 R413 P415 W420 D455 R38 S94 H95 G96 Q136 A137 C138 S173 Y174 R175 P177 W182 D217 3.4.22.61 Q14790 25079698 DKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPS 4ps0 A 1.63 BS01 III C 1 S63 R64 S65 S120 H121 G122 Q161 A162 C163 Y204 S205 W206 R207 N208 S209 W214 S249 F250 F256 S30 R31 S32 S87 H88 G89 Q128 A129 C130 Y167 S168 W169 R170 N171 S172 W177 S212 F213 F219 3.4.22.56 P42574 25079698 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYHQLHH 4ps0 B 1.63 BS01 III D 1 S63 R64 S120 H121 G122 Q161 A162 C163 Y204 S205 W206 R207 N208 S209 S249 F256 S30 R31 S87 H88 G89 Q128 A129 C130 Y165 S166 W167 R168 N169 S170 S210 F217 3.4.22.56 P42574 25079698 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDDDMHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 4ps1 B 1.73 BS01 III F 1 R258 R260 S316 H317 G318 Q358 C360 S411 Y412 R413 P415 T419 W420 D455 R37 R39 S95 H96 G97 Q137 C139 S172 Y173 R174 P176 T180 W181 D216 3.4.22.61 Q14790 25079698 LDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVERYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFP 4pv6 C 3.32 BS01 ACO C 1 L32 L78 L79 F80 V82 F86 R87 R88 M89 G90 G92 S93 E114 E121 R124 F125 Y126 K128 L26 L72 L73 F74 V76 F80 R81 R82 M83 G84 G86 S87 E108 E115 R118 F119 Y120 K122 Q97CT7 25062911 NAVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEHHH 4pv6 G 3.32 BS01 ACO G 1 L32 L78 F80 V82 R87 R88 G90 V91 G92 S93 E114 E121 R124 F125 Y126 L27 L73 F75 V77 R82 R83 G85 V86 G87 S88 E109 E116 R119 F120 Y121 Q97CT7 25062911 INAVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEHHH 4pv6 I 3.32 BS01 ACO I 1 S31 L32 L78 L79 F80 V82 R87 R88 G90 V91 G92 S93 A122 R124 F125 Y126 K128 S26 L27 L73 L74 F75 V77 R82 R83 G85 V86 G87 S88 A117 R119 F120 Y121 K123 Q97CT7 25062911 INAVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLE 4pv6 F 3.32 BS01 ACO F 1 L32 I77 L78 L79 F80 R87 R88 G90 V91 G92 S93 E114 A122 F125 Y126 K128 L25 I70 L71 L72 F73 R80 R81 G83 V84 G85 S86 E107 A115 F118 Y119 K121 Q97CT7 25062911 AVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEH 4pv6 A 3.32 BS01 COA A 1 S31 I77 L78 L79 F80 A81 V82 R87 R88 G90 V91 G92 S93 E114 N119 E121 A122 F125 Y126 K128 S26 I72 L73 L74 F75 A76 V77 R82 R83 G85 V86 G87 S88 E109 N114 E116 A117 F120 Y121 K123 Q97CT7 25062911 INAVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEHHH 4pv6 H 3.32 BS01 ACO H 1 S31 L32 L78 L79 F80 A81 V82 R87 R88 M89 G90 V91 G92 S93 N119 E121 A122 R124 F125 Y126 K128 S25 L26 L72 L73 F74 A75 V76 R81 R82 M83 G84 V85 G86 S87 N113 E115 A116 R118 F119 Y120 K122 Q97CT7 25062911 NAVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEHHH 4pv6 J 3.32 BS01 ACO J 1 L32 L78 L79 F80 V82 R87 R88 M89 G90 V91 G92 S93 E114 N119 R124 F125 Y126 L26 L72 L73 F74 V76 R81 R82 M83 G84 V85 G86 S87 E108 N113 R118 F119 Y120 Q97CT7 25062911 NAVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEH 4pv6 E 3.32 BS01 ACO E 1 L32 L78 F80 V82 R87 R88 M89 G90 V91 G92 S93 E114 E121 R124 F125 Y126 K128 L25 L71 F73 V75 R80 R81 M82 G83 V84 G85 S86 E107 E114 R117 F118 Y119 K121 Q97CT7 25062911 AVAGTIREFSPKDIESVYRIAQTSLTEYYTQALILDLHREWPESFMVYTVAGSVVGFIVGSKYSRTEARILLFAVDERFRRMGVGSALMDAFLSLCREQNMLSVRLEVRTDNDEAIRFYKKYGFVITAMLPNYYSDSSNAYTMWRIVLEHH 4qau A 1.60 BS01 HEM A 1 T39 Y43 R45 H64 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 I107 T39 Y43 R45 H64 T67 V68 A71 L89 S92 H93 H97 I99 Y103 L104 I107 P02185 25392956 VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKYDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 4qsa A 1.50 BS02 EWW A 1 H94 H96 H119 V121 F131 V135 L141 V143 L198 T199 T200 P202 L204 W209 H92 H94 H117 V119 F128 V132 L138 V140 L195 T196 T197 P199 L201 W206 4.2.1.1 P00918 25493428 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4qsi A 1.95 BS02 EWZ A 1 W5 N62 N67 Q92 H94 H96 H119 V121 L141 V143 L198 T199 T200 P202 W209 W2 N59 N64 Q89 H91 H93 H116 V118 L137 V139 L194 T195 T196 P198 W205 4.2.1.1 P00918 25493428 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4qsj A 1.70 BS02 EWW A 1 H94 H96 H119 V121 F131 V132 H136 V143 L198 T199 V200 P202 W209 H93 H95 H118 V120 F130 V131 H135 V142 L197 T198 V199 P201 W208 4.2.1.1 Q8N1Q1 25493428 RLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4r3b A 1.37 BS01 MA4 A 1 V224 P226 I231 I246 A248 L250 V261 I263 I279 A280 A284 I287 E288 V199 P201 I206 I220 A222 L224 V234 I236 I252 A253 A257 I260 E261 3.5.2.6 P0AD64 25536850 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4r3b A 1.37 BS02 3GE A 1 M69 S70 D104 N132 E166 T167 N170 G236 A237 M44 S45 D79 N107 E141 T142 N145 G211 A212 3.5.2.6 P0AD64 25536850 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4r3b A 1.37 BS03 MA4 A 2 L220 R244 I246 N276 I279 L195 R218 I220 N249 I252 3.5.2.6 P0AD64 25536850 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4r7g A 2.90 BS02 MG A 2 I697 E718 I686 E707 6.3.5.3 P74881 25551173 GLVPRGSHMMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLIGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG 4r7g A 2.90 BS03 MG A 3 S886 E896 S875 E885 6.3.5.3 P74881 25551173 GLVPRGSHMMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLIGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG 4r7g A 2.90 BS04 ADP A 1 T386 G387 Y388 F389 K649 L652 V653 Q668 P676 A678 D679 E718 N722 S886 T394 G395 Y396 F397 K638 L641 V642 Q657 P665 A667 D668 E707 N711 S875 6.3.5.3 P74881 25551173 GLVPRGSHMMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLIGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG 4r9r A 2.90 BS01 NAD A 1 G14 I15 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 M161 K165 A191 P193 I194 T196 G12 I13 I14 S18 I19 F39 L61 D62 V63 S92 I93 G94 I120 M145 D146 F147 M159 K163 A189 P191 I192 T194 1.3.1.9 I6Y6N7 25568071 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9r A 2.90 BS02 3KX A 1 G96 F149 Y158 M161 I215 G94 F147 Y156 M159 I213 1.3.1.9 I6Y6N7 25568071 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9r C 2.90 BS02 3KX C 1 G96 F149 Y158 P193 M199 I215 G94 F147 Y156 P191 M197 I213 1.3.1.9 I6Y6N7 25568071 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9r E 2.90 BS02 3KX E 1 G96 Y158 M161 M199 I215 G94 Y156 M159 M197 I213 1.3.1.9 I6Y6N7 25568071 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9r G 2.90 BS01 NAD G 1 G14 I16 S20 I21 F41 L63 D64 V65 S94 I95 G96 I122 M147 D148 F149 K165 G192 P193 I194 T196 G12 I14 S18 I19 F39 L61 D62 V63 S92 I93 G94 I120 M145 D146 F147 K163 G190 P191 I192 T194 1.3.1.9 I6Y6N7 25568071 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9r G 2.90 BS02 3KX G 1 G96 F149 Y158 P193 M199 I215 L218 G94 F147 Y156 P191 M197 I213 L216 1.3.1.9 I6Y6N7 25568071 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9s A 3.20 BS02 3KY A 1 G96 F149 Y158 M161 M199 I215 G95 F148 Y157 M160 M198 I214 1.3.1.9 I6Y6N7 25568071 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9s E 3.20 BS01 NAD E 1 G14 I16 S20 I21 F41 L63 D64 V65 Q66 S94 I95 I122 M147 D148 F149 M161 K165 A191 G192 P193 I194 T196 G13 I15 S19 I20 F40 L62 D63 V64 Q65 S93 I94 I121 M146 D147 F148 M160 K164 A190 G191 P192 I193 T195 1.3.1.9 I6Y6N7 25568071 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4r9s E 3.20 BS02 3KY E 1 G96 M103 F149 Y158 P193 M199 I215 L218 G95 M102 F148 Y157 P192 M198 I214 L217 1.3.1.9 I6Y6N7 25568071 TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4rcd A 1.90 BS01 3LL A 1 G11 Q12 G13 L30 D32 S35 Y71 W76 F108 I118 I126 R128 Y198 D228 G230 G13 Q14 G15 L32 D34 S37 Y73 W78 F110 I120 I128 R130 Y190 D220 G222 3.4.23.46 P56817 25363711 FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4rel A 1.75 BS01 KMP A 1 H17 L82 F116 N137 Y145 P179 D181 F192 L196 F365 G366 D367 H17 L82 F116 N137 Y145 P179 D181 F192 L196 F365 G366 D367 2.4.1.115 A4F1R4 25556637 MKNKQHVAIFPFPFGSHLPPLLNLVLKLAHIAPNTSFSFIGTHSSNAFLFTKRHIPNNIRVFTISDGIPEGHVPANNPIEKLDLFLSTGPDNLRKGIELAVAETKQSVTCIIADAFVTSSLLVAQTLNVPWIAFWPNVSCSLSLYFNIDLIRDKCSKDAKNATLDFLPGLSKLRVEDVPQDMLDVGEKETLFSRTLNSLGVVLPQAKAVVVNFFAELDPPLFVKYMRSKLQSLLYVVPLPCPQLLLPEIDSNGCLSWLDSKSSRSVAYVCFGTVVSPPPQEVVAVAEALEESGFPFVWALKESLLSILPKGFVERTSTRGKVVSWVPQSHVLSHGSVGVFVTHCGANSVMESVSNGVPMICRPFFGDQGIAARVIQDIWEVGVIVEGKVFTKNGFVKSLNLILVQEDGKKIRDNALKVKQIVQDAVGPHGQAAEDFNTLVEVISSS 4rem A 2.55 BS01 DLM A 1 H17 P78 I79 L82 F116 N137 Y145 P179 D181 F192 L196 F365 G366 D367 H17 P78 I79 L82 F116 N137 Y145 P179 D181 F192 L196 F365 G366 D367 2.4.1.115 A4F1R4 25556637 MKNKQHVAIFPFPFGSHLPPLLNLVLKLAHIAPNTSFSFIGTHSSNAFLFTKRHIPNNIRVFTISDGIPEGHVPANNPIEKLDLFLSTGPDNLRKGIELAVAETKQSVTCIIADAFVTSSLLVAQTLNVPWIAFWPNVSCSLSLYFNIDLIRDKCSKDAKNATLDFLPGLSKLRVEDVPQDMLDVGEKETLFSRTLNSLGVVLPQAKAVVVNFFAELDPPLFVKYMRSKLQSLLYVVPLPCPQLLLPEIDSNGCLSWLDSKSSRSVAYVCFGTVVSPPPQEVVAVAEALEESGFPFVWALKESLLSILPKGFVERTSTRGKVVSWVPQSHVLSHGSVGVFVTHCGANSVMESVSNGVPMICRPFFGDQGIAARVIQDIWEVGVIVEGKVFTKNGFVKSLNLILVQEDGKKIRDNALKVKQIVQDAVGPHGQAAEDFNTLVEVISSS 4ri6 A 1.52 BS01 GSH A 1 S13 T14 A15 L37 Q42 K43 G54 Q55 V56 P57 E68 S69 R70 S12 T13 A14 L36 Q41 K42 G53 Q54 V55 P56 E67 S68 R69 2.5.1.18 A9PHH6 25566286 ATPVTIYGPPLSTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLEMRKNA 4ri6 A 1.52 BS02 MES A 1 L12 S13 T14 L37 H119 F123 L11 S12 T13 L36 H118 F122 2.5.1.18 A9PHH6 25566286 ATPVTIYGPPLSTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLEMRKNA 4ri6 B 1.52 BS02 MES B 1 L12 S13 T14 F123 L11 S12 T13 F122 2.5.1.18 A9PHH6 25566286 ATPVTIYGPPLSTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLEMRKNA 4ri7 A 1.80 BS01 GSH A 1 C13 T14 A15 L37 Q42 K43 G54 Q55 V56 P57 E68 S69 C12 T13 A14 L36 Q41 K42 G53 Q54 V55 P56 E67 S68 2.5.1.18 A9PHH6 25566286 ATPVTIYGPPLCTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLEMRKNA 4rkg A 2.50 BS01 NUC I 1 C525 R526 C527 G528 R543 P545 C3 R4 C5 G6 R14 P16 6.3.2.- P50534 25452275 PKCRCGITTCRNSRCPCYKSYNSCAGCHCVGCKNPHK 4rkg A 2.50 BS02 ZN A 1 C525 C527 C539 C544 C3 C5 C10 C15 6.3.2.- P50534 25452275 PKCRCGITTCRNSRCPCYKSYNSCAGCHCVGCKNPHK 4rkg B 2.50 BS01 NUC H 1 R526 S542 R543 R5 S21 R22 6.3.2.- P50534 25452275 KPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKE 4rkg B 2.50 BS02 NUC I 1 C525 R526 C527 G528 S533 N534 R543 P545 C4 R5 C6 G7 S12 N13 R22 P24 6.3.2.- P50534 25452275 KPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKE 4rkg B 2.50 BS03 ZN B 1 C525 C527 C539 C544 C4 C6 C18 C23 6.3.2.- P50534 25452275 KPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKE 4rkg B 2.50 BS04 ZN B 2 C525 C539 C553 C558 C561 C4 C18 C32 C37 C40 6.3.2.- P50534 25452275 KPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKE 4rkh C 2.00 BS01 NUC B 1 C525 R526 C527 G528 S532 S533 N534 R543 P545 C4 R5 C6 G7 S9 S10 N11 R20 P22 6.3.2.- P50534 25452275 KPKCRCGISSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKEDYV 4rkh D 2.00 BS01 NUC A 1 R526 C527 G528 S533 N534 R543 P545 R8 C9 G10 S14 N15 R24 P26 6.3.2.- P50534 25452275 SPPKPKCRCGISSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKEDYV 4rlo A 2.53 BS01 3T3 A 1 L97 G98 K99 G100 G103 V105 A121 V156 L172 E173 Y174 L175 E179 E222 M225 T235 D236 L13 G14 K15 G16 G19 V21 A37 V58 L72 E73 Y74 L75 E79 E122 M125 T135 D136 2.7.11.1 P23443 25356520 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAERNILEEVKHPFIVDLIYAFQTKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKEGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKP 4rlo B 2.53 BS01 STU B 1 L97 G98 K99 V105 A121 L172 E173 Y174 L175 G178 E179 E222 M225 L13 G14 K15 V21 A37 L65 E66 Y67 L68 G71 E72 E115 M118 2.7.11.1 P23443 25356520 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESITIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPL 4rlp A 2.79 BS01 72B A 1 L97 G98 K99 G100 G103 V105 A121 K123 L172 E173 Y174 L175 E179 E222 M225 T235 L13 G14 K15 G16 G19 V21 A37 K39 L72 E73 Y74 L75 E79 E122 M125 T135 2.7.11.1 P23443 25356520 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKRNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPL 4rpa A 2.10 BS01 MN A 1 D15 D75 H97 H98 T119 D149 D14 D74 H96 H97 T118 D148 3.6.1.1 D9RMT1 25576794 AKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK 4rpa A 2.10 BS02 MN A 2 H9 D13 A16 D75 H8 D12 A15 D74 3.6.1.1 D9RMT1 25576794 AKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK 4rpa B 2.10 BS01 MN B 1 D15 D75 H97 H98 D149 D14 D74 H96 H97 D148 3.6.1.1 D9RMT1 25576794 AKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK 4rpg B 2.40 BS01 FAD B 1 V13 G14 G16 L37 E38 R39 R40 G45 Y62 G63 A64 H65 L66 T223 D224 W225 F226 G245 L263 Y327 Y328 G359 R360 L367 D368 M369 A372 V10 G11 G13 L34 E35 R36 R37 G42 Y59 G60 A61 H62 L63 T220 D221 W222 F223 G242 L260 Y324 Y325 G356 R357 L364 D365 M366 A369 5.4.99.9 P9WIQ1 25562380 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rpg B 2.40 BS02 GDU B 1 L66 H89 V91 F102 F157 V158 Y161 T162 W166 N177 I178 R180 L181 Y191 F192 N282 N284 R292 Y328 Y366 L63 H86 V88 F99 F154 V155 Y158 T159 W163 N174 I175 R177 L178 Y188 F189 N279 N281 R289 Y325 Y363 5.4.99.9 P9WIQ1 25562380 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rpg A 2.40 BS02 UDP A 1 F102 L141 F157 V158 Y161 T162 W166 N177 I178 R180 L181 Y191 N282 N284 R292 Y328 Y366 F99 L138 F154 V155 Y158 T159 W163 N174 I175 R177 L178 Y188 N279 N281 R289 Y325 Y363 5.4.99.9 P9WIQ1 25562380 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQ 4rpg C 2.40 BS02 UDP C 1 F102 F157 V158 Y161 T162 W166 N177 I178 R180 L181 Y191 N282 N284 R292 Y328 Y366 F99 F154 V155 Y158 T159 W163 N174 I175 R177 L178 Y188 N279 N281 R289 Y325 Y363 5.4.99.9 P9WIQ1 25562380 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rph B 2.60 BS01 FAD B 1 V13 G14 G16 F17 F18 L37 E38 R39 R40 G45 G63 A64 H65 L66 D224 F226 T244 G245 L263 Y327 Y328 G359 R360 L367 D368 M369 A372 V9 G10 G12 F13 F14 L33 E34 R35 R36 G41 G59 A60 H61 L62 D220 F222 T240 G241 L259 Y323 Y324 G355 R356 L363 D364 M365 A368 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rph A 2.60 BS01 FAD A 1 V13 G14 G16 F17 F18 L37 E38 R39 R40 G45 Y62 G63 A64 H65 L66 D224 W225 F226 G245 P246 R249 L263 Y327 Y328 G359 R360 L367 D368 M369 A372 V9 G10 G12 F13 F14 L33 E34 R35 R36 G41 Y58 G59 A60 H61 L62 D220 W221 F222 G241 P242 R245 L259 Y323 Y324 G355 R356 L363 D364 M365 A368 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQ 4rph C 2.60 BS01 FAD C 1 V13 G14 G16 F17 F18 L37 E38 R39 R40 G45 N46 G63 A64 H65 L66 T223 D224 W225 F226 G245 L263 Y327 Y328 G359 R360 L367 D368 M369 A372 V9 G10 G12 F13 F14 L33 E34 R35 R36 G41 N42 G59 A60 H61 L62 T219 D220 W221 F222 G241 L259 Y323 Y324 G355 R356 L363 D364 M365 A368 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rpk B 2.55 BS01 FAD B 1 V13 G14 G16 F17 F18 L37 E38 R39 R40 G45 N46 Y62 A64 H65 L66 T223 D224 W225 G245 R249 L263 Y327 Y328 G359 R360 L367 D368 M369 V9 G10 G12 F13 F14 L33 E34 R35 R36 G41 N42 Y58 A60 H61 L62 T219 D220 W221 G241 R245 L259 Y323 Y324 G355 R356 L363 D364 M365 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rpk B 2.55 BS02 3UA B 1 A64 L66 H89 V91 F102 F157 V158 Y161 T162 Q165 W166 N177 I178 R180 L181 Y191 V280 N282 N284 R292 Y328 Y366 A60 L62 H85 V87 F98 F153 V154 Y157 T158 Q161 W162 N173 I174 R176 L177 Y187 V276 N278 N280 R288 Y324 Y362 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rpl B 2.25 BS01 FAD B 1 V13 G14 G16 F17 F18 L37 E38 R39 R40 G45 N46 Y62 A64 H65 L66 T223 D224 W225 F226 G245 L263 Y327 R360 L367 D368 M369 A372 V9 G10 G12 F13 F14 L33 E34 R35 R36 G41 N42 Y58 A60 H61 L62 T219 D220 W221 F222 G241 L259 Y323 R356 L363 D364 M365 A368 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rpl C 2.25 BS02 3UC C 1 L66 H89 V91 F102 Y161 T162 Q165 Y191 F192 N282 N284 R292 Y328 Y366 L62 H85 V87 F98 Y157 T158 Q161 Y187 F188 N278 N280 R288 Y324 Y362 5.4.99.9 P9WIQ1 25562380 TARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLL 4rr2 D 2.65 BS01 SF4 D 1 P285 P286 C287 C367 C384 C424 L441 P444 P258 P259 C260 C340 C357 C397 L414 P417 2.7.7.- P49643 25550159 YPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKISPGGISQILDLVKGTHYQVACQKYFEMIHNVDDCGFSLNHPNQFFCESQRILN 4rvn A 2.20 BS03 COA A 1 S135 A163 G164 N165 S166 I184 Y187 R190 K336 V406 T407 S136 A164 G165 N166 S167 I185 Y188 R191 K337 V407 T408 Q8AAN6 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEAVRVKDLRDN 4rvn B 2.20 BS02 AMP B 1 S94 G213 A214 E215 P216 N235 S236 F237 G238 M239 T240 D304 I325 R328 K424 S92 G209 A210 E211 P212 N231 S232 F233 G234 M235 T236 D300 I321 R324 K416 Q8AAN6 TQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLR 4rwv A 1.86 BS01 III B 1 F354 R361 R367 L369 V371 Q374 M375 Q379 N530 L531 E534 M535 F58 R65 R71 L73 V75 Q78 M79 Q83 N234 L235 E238 M239 O00482 SPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAK 4rwv A 1.86 BS02 PIZ A 1 T341 F342 M345 C346 A349 S383 H390 I416 Q419 A420 G421 A422 T423 L424 A513 Y516 K520 T45 F46 M49 C50 A53 S87 H94 I120 Q123 A124 G125 A126 T127 L128 A217 Y220 K224 O00482 SPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAK 4rxw B 1.73 BS01 III A 1 F1 N3 Q4 H5 L6 C7 L11 A14 L15 C19 R22 G23 F24 F25 Y26 T27 P28 K29 F1 N3 Q4 H5 L6 C7 L11 A14 L15 C19 R22 G23 F24 F25 Y26 T27 P28 K29 P01308 FVNQHLCGSHLVEALYLVCGERGFFYTPKT 4rzm A 2.33 BS01 LSD A 1 D170 S174 W175 R177 H186 M189 A190 S193 M219 S224 L228 H231 L233 I249 Y251 W270 D164 S168 W169 R171 H180 M183 A184 S187 M213 S218 L222 H225 L227 I243 Y245 W264 5.5.1.- B6ZK72 25535803 GRHMPAETVRKEVALEYCRRVNAGELEGVLQLFAPDARLVDPLGTEPVVGRAALAARLAPALRGAVHEEPGRPYAAHDGTSVVLPATVTVRGRTRVMGVIEVGEDGLIREMRVMWGVTDSSWTARPAPDEERRKELAREHCLRINDGDVDGLLKLYSPRIRFEDPVGSWTRTGLEALRAHATMAVGSNVRETAGLTVAGQDGRHAAVTVSATMDYLPSGPLLARHHLMTLPAPADPHRALIGIEYVMVIGVDADGLIDEMRAYWGATDVSLLDP 4s0y A 1.93 BS02 HEM A 1 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 V354 L417 L433 I436 R440 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 V354 L417 L433 I436 R440 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 4s0y A 1.93 BS03 40R A 1 H109 F113 R255 E258 H109 F113 R255 E258 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 4u7d A 3.40 BS02 NUC Q 1 F322 S323 Q324 K325 A346 T371 V372 A373 K393 M429 V430 E433 A525 R528 Y564 F260 S261 Q262 K263 A284 T309 V310 A311 K331 M367 V368 E371 A460 R463 Y499 3.6.4.12 P46063 SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTK 4u7d B 3.40 BS01 NUC P 1 F322 S323 Q324 K325 H345 A346 T371 V372 A373 K393 M429 E433 R528 F260 S261 Q262 K263 H283 A284 T309 V310 A311 K331 M367 E371 R463 3.6.4.12 P46063 SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTK 4u7d B 3.40 BS02 NUC Q 1 T511 L513 K514 I567 Y569 T446 L448 K449 I502 Y504 3.6.4.12 P46063 SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTK 4u9e A 2.80 BS01 HEM A 1 E4 M7 N11 F61 F65 C98 C101 H102 E4 M7 N11 F46 F50 C83 C86 H87 P0ABE7 25525249 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSMHDFRHGFWILIGQIHDALHLANEGKVKEAQHAAEQLKCTCNHCHQAYR 4u9e A 2.80 BS02 CA A 1 D5 E8 D5 E8 P0ABE7 25525249 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSMHDFRHGFWILIGQIHDALHLANEGKVKEAQHAAEQLKCTCNHCHQAYR 4u9e A 2.80 BS03 CA A 2 K19 D21 K19 D21 P0ABE7 25525249 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSMHDFRHGFWILIGQIHDALHLANEGKVKEAQHAAEQLKCTCNHCHQAYR 4u9e A 2.80 BS04 CA A 3 E4 E8 E4 E8 P0ABE7 25525249 ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMAAAAADAWSMHDFRHGFWILIGQIHDALHLANEGKVKEAQHAAEQLKCTCNHCHQAYR 4u9h S 0.89 BS01 SF4 S 1 E16 C17 G19 C20 G112 T113 C114 V120 G149 C150 P151 E14 C15 G17 C18 G110 T111 C112 V118 G147 C148 P149 1.12.2.1 P21853 GPRRPSVVYLHNAECTGCSESVLRAFEPYIDTLILDTLSLDYHETIMAAAGDAAEAALEQAVNSPHGFIAVVEGGIPTAANGIYGKVANHTMLDICSRILPKAQAVIAYGTCATFGGVQAAKPNPTGAKGVNDALKHLGVKAINIAGCPPNPYNLVGTIVYYLKNKAAPELDSLNRPTMFFGQTVHEQCPRLPHFDAGEFAPSFESEEARKGWCLYELGCKGPVTMNNCPKIKFNQTNWPVDAGHPCIGCSEPDFWDAMTPFYQN 4u9h S 0.89 BS02 SF4 S 2 H188 C191 R193 L194 F197 C216 L217 Y218 C222 G224 P225 V243 H186 C189 R191 L192 F195 C214 L215 Y216 C220 G222 P223 V241 1.12.2.1 P21853 GPRRPSVVYLHNAECTGCSESVLRAFEPYIDTLILDTLSLDYHETIMAAAGDAAEAALEQAVNSPHGFIAVVEGGIPTAANGIYGKVANHTMLDICSRILPKAQAVIAYGTCATFGGVQAAKPNPTGAKGVNDALKHLGVKAINIAGCPPNPYNLVGTIVYYLKNKAAPELDSLNRPTMFFGQTVHEQCPRLPHFDAGEFAPSFESEEARKGWCLYELGCKGPVTMNNCPKIKFNQTNWPVDAGHPCIGCSEPDFWDAMTPFYQN 4uuq A 2.36 BS01 64D A 1 G60 A61 S132 M133 L158 N162 S165 L215 G220 L223 L224 C252 G45 A46 S117 M118 L143 N147 S150 L200 G205 L208 L209 C237 3.1.1.23 Q99685 25560837 SPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTA 4uuq B 2.36 BS01 64D B 1 G60 A61 S132 M133 L158 N162 G220 L223 L224 G33 A34 S105 M106 L131 N135 G193 L196 L197 3.1.1.23 Q99685 25560837 DLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTA 4w5a A 2.60 BS01 III C 1 Y43 D47 D48 I49 D52 M56 D57 E58 A64 E65 G66 G67 N68 L69 I70 C71 D73 Y43 D47 D48 I49 D52 M56 D57 E58 A64 E65 G66 G67 N68 L69 I70 C71 D73 3.6.4.12 P46100 25538301 GPLGSMGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDENNQWYCYICHPEPLLDLVTACNSVYENLE 4w5a A 2.60 BS02 ZN A 1 C11 C14 C37 C40 C11 C14 C37 C40 3.6.4.12 P46100 25538301 GPLGSMGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDENNQWYCYICHPEPLLDLVTACNSVYENLE 4w5a B 2.60 BS01 III D 1 Y43 S46 D47 D48 D52 M56 D57 E58 A64 E65 G66 G67 N68 L69 I70 C71 D73 Y43 S46 D47 D48 D52 M56 D57 E58 A64 E65 G66 G67 N68 L69 I70 C71 D73 3.6.4.12 P46100 25538301 GPLGSMGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDENNQWYCYICHPEPLLDLVTACNSVYEN 4w5a E 2.60 BS01 III F 1 Y43 D47 D48 I49 D52 M56 E58 Q59 A64 E65 G66 G67 N68 L69 I70 C71 C72 I96 Y30 D34 D35 I36 D39 M43 E45 Q46 A51 E52 G53 G54 N55 L56 I57 C58 C59 I83 3.6.4.12 P46100 25538301 IVSCTACGQQVNIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDENNQWYCYICHPEPLLDLVTACNSVYENL 4wb5 A 1.64 BS01 III I 1 T51 G52 S53 L82 K83 Q84 E127 F129 R133 K168 P169 E170 F187 L198 G200 T201 P202 E203 E230 Y235 P236 F239 A240 D241 I246 Y330 T39 G40 S41 L70 K71 Q72 E115 F117 R121 K156 P157 E158 F175 L186 G188 T189 P190 E191 E218 Y223 P224 F227 A228 D229 I234 Y318 2.7.11.11 P17612 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb5 A 1.64 BS02 ATP A 1 G50 G52 S53 F54 G55 V57 A70 K72 V104 M120 E121 Y122 V123 E127 D166 K168 E170 N171 L173 T183 D184 F327 G38 G40 S41 F42 G43 V45 A58 K60 V92 M108 E109 Y110 V111 E115 D154 K156 E158 N159 L161 T171 D172 F315 2.7.11.11 P17612 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb6 A 2.10 BS01 III I 1 T51 G52 S53 F54 E127 F129 R133 K168 P169 E170 F187 T201 E203 E230 Y235 P236 F239 A240 Y330 T39 G40 S41 F42 E115 F117 R121 K156 P157 E158 F175 T189 E191 E218 Y223 P224 F227 A228 Y318 2.7.11.11 P17612 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYRAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb6 A 2.10 BS02 ATP A 1 L49 G50 T51 G52 S53 F54 G55 V57 A70 K72 V104 M120 E121 V123 E127 D166 K168 E170 N171 L173 T183 D184 F327 L37 G38 T39 G40 S41 F42 G43 V45 A58 K60 V92 M108 E109 V111 E115 D154 K156 E158 N159 L161 T171 D172 F315 2.7.11.11 P17612 ESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYRAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb6 B 2.10 BS01 III J 1 T51 G52 S53 F54 E127 F129 R133 K168 P169 E170 F187 T201 P202 E203 E230 Y235 P236 A240 D241 P243 Y330 T44 G45 S46 F47 E120 F122 R126 K161 P162 E163 F180 T194 P195 E196 E223 Y228 P229 A233 D234 P236 Y323 2.7.11.11 P17612 KGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYRAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb7 A 1.90 BS01 III I 1 T106 G107 S108 F109 E182 F184 R188 G191 K223 P224 E225 F242 L253 G255 T256 P257 E258 L260 E285 Y290 P291 A295 D296 Y302 Y385 T106 G107 S108 F109 E182 F184 R188 G191 K223 P224 E225 F242 L253 G255 T256 P257 E258 L260 E285 Y290 P291 A295 D296 Y302 Y385 2.7.11.11 P17612 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb7 A 1.90 BS04 ZN A 2 S194 H197 S194 H197 2.7.11.11 P17612 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb7 A 1.90 BS05 ZN A 3 E176 Q236 E176 Q236 2.7.11.11 P17612 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb7 B 1.90 BS01 III J 1 T106 G107 S108 F109 E182 F184 R188 R192 K223 P224 E225 F242 G255 T256 P257 E258 L260 E285 Y290 P291 F294 A295 D296 I301 Y302 Y385 T106 G107 S108 F109 E182 F184 R188 R192 K223 P224 E225 F242 G255 T256 P257 E258 L260 E285 Y290 P291 F294 A295 D296 I301 Y302 Y385 2.7.11.11 P17612 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wb7 B 1.90 BS04 ZN B 2 E79 D80 E79 D80 2.7.11.11 P17612 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 4wet A 1.63 BS01 WEF A 1 H32 L40 P163 Q164 T168 M171 F174 H31 L39 P162 Q163 T167 M170 F173 1.8.4.2 C5WBA2 25556635 QYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wet B 1.63 BS01 WEF A 1 M64 G65 M64 G65 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wey A 1.55 BS01 EG6 B 1 H32 F36 L40 P151 P163 T168 M171 F174 H32 F36 L40 P151 P163 T168 M171 F174 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wey B 1.55 BS01 EG6 B 1 M64 G65 L68 M64 G65 L68 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wf5 A 1.45 BS01 WF4 A 1 Q164 T168 M171 F174 Q164 T168 M171 F174 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wf5 A 1.45 BS02 WF4 A 2 H32 Q35 F36 L40 H32 Q35 F36 L40 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wf5 B 1.45 BS01 WF4 A 3 F29 G65 G66 F29 G65 G66 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4wf5 B 1.45 BS02 CU B 1 A1 E4 A1 E4 1.8.4.2 C5WBA2 25556635 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 4whm A 1.85 BS01 UDP A 1 S16 C270 G272 T273 A299 W325 V326 Q328 H343 G345 A346 N347 S348 E351 S16 C270 G272 T273 A299 W325 V326 Q328 H343 G345 A346 N347 S348 E351 2.4.1.115 A4F1R4 25556637 MKNKQHVAIFPFPFGSHLPPLLNLVLKLAHIAPNTSFSFIGTHSSNAFLFTKRHIPNNIRVFTISDGIPEGHVPANNPIEKLDLFLSTGPDNLRKGIELAVAETKQSVTCIIADAFVTSSLLVAQTLNVPWIAFWPNVSCSLSLYFNIDLIRDKCSKDAKNATLDFLPGLSKLRVEDVPQDMLDVGEKETLFSRTLNSLGVVLPQAKAVVVNFFAELDPPLFVKYMRSKLQSLLYVVPLPCPQLLLPEIDSNGCLSWLDSKSSRSVAYVCFGTVVSPPPQEVVAVAEALEESGFPFVWALKESLLSILPKGFVERTSTRGKVVSWVPQSHVLSHGSVGVFVTHCGANSVMESVSNGVPMICRPFFGDQGIAARVIQDIWEVGVIVEGKVFTKNGFVKSLNLILVQEDGKKIRDNALKVKQIVQDAVGPHGQAAEDFNTLVEVISSS 4wk8 F 3.40 BS02 NUC B 1 P378 T380 N383 H387 K416 P42 T44 N47 H51 K80 Q9BZS1 25567984 RPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKK 4wwe E 3.40 BS01 NUC 4 1 S76 S78 R83 S75 S77 R82 Q5SHQ0 25562208 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4wwe P 3.40 BS01 NUC 4 1 R10 P78 N89 R10 P78 N89 P60489 25562208 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4wwe R 3.40 BS01 NUC s 1 R17 R25 F29 S31 L32 K33 H34 Y36 Q38 G45 V46 T47 A55 K62 T63 Y92 K93 H95 G96 R97 R7 R15 F19 S21 L22 K23 H24 Y26 Q28 G35 V36 T37 A45 K52 T53 Y82 K83 H85 G86 R87 Q5SHQ4 25562208 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG 4wwe Z 3.40 BS01 NUC s 1 R10 P15 R19 Y29 N30 R31 N34 R72 Q73 E84 H85 D87 F89 R8 P13 R17 Y27 N28 R29 N32 R70 Q71 E82 H83 D85 F87 Q5SHZ1 25562208 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPE 4wwe a 3.40 BS01 NUC 4 1 A2 H3 K4 G8 A1 H2 K3 G7 P60493 25562208 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4wwe a 3.40 BS02 NUC s 1 Q70 R72 Q69 R71 P60493 25562208 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4wwt E 3.40 BS01 NUC 4 1 S78 R83 S77 R82 Q5SHQ0 25562208 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4wwt E 3.40 BS02 NUC s 1 L3 N27 W29 E30 Q66 K67 A69 V70 T71 V92 T93 R95 R96 R98 L2 N26 W28 E29 Q65 K66 A68 V69 T70 V91 T92 R94 R95 R97 Q5SHQ0 25562208 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4wwt P 3.40 BS01 NUC s 1 L17 G19 Q141 L17 G19 Q141 P60489 25562208 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4wwt R 3.40 BS01 NUC s 1 R17 R25 S27 F29 S31 L32 K33 H34 Y36 Q38 I40 V46 T47 S50 A55 K62 T63 Y92 K93 H95 G96 R97 R7 R15 S17 F19 S21 L22 K23 H24 Y26 Q28 I30 V36 T37 S40 A45 K52 T53 Y82 K83 H85 G86 R87 Q5SHQ4 25562208 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG 4wwt Z 3.40 BS01 NUC s 1 R10 P15 R19 G26 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R8 P13 R17 G24 Y27 N28 R29 N32 K34 R70 Q71 N73 R77 E82 H83 D85 F87 Q5SHZ1 25562208 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPE 4wwt a 3.40 BS01 NUC 4 1 A2 K4 L7 R11 A1 K3 L6 R10 P60493 25562208 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4x0g A 3.21 BS01 NUC E 1 T49 L50 S51 K53 P54 S55 F58 K66 R93 T97 K105 T47 L48 S49 K51 P52 S53 F56 K64 R91 T95 K103 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSR 4x0g A 3.21 BS02 NUC F 1 R33 K34 P56 A57 R59 K99 D102 K105 R31 K32 P54 A55 R57 K97 D100 K103 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSR 4x0g B 3.21 BS01 NUC E 1 R33 R42 P56 A57 R59 K99 D102 K105 M106 R31 R40 P54 A55 R57 K97 D100 K103 M104 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSRM 4x0g B 3.21 BS02 NUC F 1 T49 L50 S51 K53 S55 F58 R63 K66 R90 R93 T97 A101 K105 T47 L48 S49 K51 S53 F56 R61 K64 R88 R91 T95 A99 K103 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSRM 4x0g C 3.21 BS01 NUC G 1 T49 L50 S51 K53 S55 F58 R63 R90 R93 T97 K105 R108 T47 L48 S49 K51 S53 F56 R61 R88 R91 T95 K103 R106 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSRM 4x0g D 3.21 BS01 NUC G 1 R33 K34 R42 P56 A57 R59 K99 D102 K105 M106 R31 K32 R40 P54 A55 R57 K97 D100 K103 M104 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSR 4x0g D 3.21 BS02 NUC H 1 T49 L50 S51 K53 P54 S55 F58 K66 R90 R93 T97 K105 R108 T47 L48 S49 K51 P52 S53 F56 K64 R88 R91 T95 K103 R106 Q9VR17 25561495 PMVTIGPNGTEVSRISLSAINWAMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSCDMTPREVRTAITTKCADENKMLRSR 4x33 A 1.45 BS01 FE A 1 C25 C27 C47 C50 C24 C26 C46 C49 Q3E840 STYDEIEIEDMTFEPENQMFTYPCPCGDRFQIYLDDMFEGEKVAVCPSCSLMIDVVHHHH 4x33 B 1.45 BS01 DXE B 1 R13 G18 H19 D20 R12 G17 H18 D19 P31386 SCVYAFGSNGQRQLGLGHDEDMDTPQRSVPGAIVRKIACGGNHSVMLTNDGNLVGCGDNRRGELDSAQALRQVHDWRPVEVPAPVVDVACGWDTTVIVDADGRVWQRGGGCYEFTQQHVPLNSNDERIAVYGCFQNFVVVQGTRVYGWGSNTKCQLQEPKSRSLKEPVLVYDTGSVAVDYVAMGKDFMVIVDEGGRIVHASGRLPTGFELKQQQKRHNLVVLCMWTSIHLWNARLNTVESFGRGTHSQLFPQERLDFPIVGVATGSEHGILTTANQHCYNVYCWGWGEHGNCGPQKGSQPGLQLVGQYSGKPRVFGGCATTWIVL 4x3e A 2.30 BS01 III B 1 F97 Y148 Y308 C324 D362 I363 W364 Y365 Q382 A411 R414 F17 Y68 Y228 C244 D282 I283 W284 Y285 Q302 A331 R334 O75530 SFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDR 4xck A 2.37 BS01 RIB A 1 N11 D13 G38 G39 K40 N43 A95 I107 I109 E140 T248 D252 A288 N11 D13 G38 G39 K40 N43 A95 I107 I109 E140 T248 D252 A288 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck A 2.37 BS02 ADP A 1 T220 G222 S223 F240 V242 T247 A250 F254 H276 A279 V283 T220 G222 S223 F240 V242 T247 A250 F254 H276 A279 V283 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck A 2.37 BS03 CS A 1 D246 T248 S282 R285 G287 S291 D246 T248 S282 R285 G287 S291 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck B 2.37 BS01 ADP B 1 N184 T220 G222 F240 V242 A244 A250 G251 F254 H276 A279 V283 N184 T220 G222 F240 V242 A244 A250 G251 F254 H276 A279 V283 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck B 2.37 BS02 ADP B 2 N11 D13 G38 G39 K40 N43 I107 I109 E140 T247 T248 D252 A288 N11 D13 G38 G39 K40 N43 I107 I109 E140 T247 T248 D252 A288 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck B 2.37 BS03 CS B 1 D246 T248 A249 S282 R285 G287 S291 D246 T248 A249 S282 R285 G287 S291 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck C 2.37 BS02 ADP C 1 N184 T220 G222 S223 G225 V226 F240 V242 A250 G251 H276 A279 V283 N184 T220 G222 S223 G225 V226 F240 V242 A250 G251 H276 A279 V283 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck C 2.37 BS03 CS C 1 D246 T248 S282 V283 R285 G287 S291 D246 T248 S282 V283 R285 G287 S291 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck D 2.37 BS01 ADP D 1 N184 T220 L221 G222 S223 V226 F240 V242 G251 F254 H276 A279 V283 N184 T220 L221 G222 S223 V226 F240 V242 G251 F254 H276 A279 V283 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xck D 2.37 BS02 CS D 1 D246 S282 R285 G287 S291 D246 S282 R285 G287 S291 2.7.1.15 A5F1B7 25408351 MNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEVEAFLAEHS 4xcz A 1.50 BS01 FON A 1 F76 D77 K78 I79 I80 D126 H127 G128 I129 D130 Y187 S189 K190 F76 D77 K78 I79 I80 D126 H127 G128 I129 D130 Y187 S189 K190 2.1.2.9 F8RC03 25574689 MKLIIAGKNNIAVDVTKWIIKTISDIELYSVCNENDHGNDSFQLSFKKFCIQFNIPIISLEDAYHLEDAIFLSLEFDKIIHPSKFTHNRIFNIHFSYLPAYKGMYTSAWPILNNEQESGVTLHKIDHGIDTGAIIDQQKFPLDIEETAKTLYLKYIKIGTEIVIKNLPALISGNYSIVEQSAIKSSYYSKKSIDYKNLMIDLNKTAHEILQQIRAFTFRDYQLPRIDDIDIFHGEILSSKSLSKPGTILEKNNYHLILSTIDYDIKLYSDNFDEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNFMSTFN 4xcz A 1.50 BS02 T3Q A 1 K8 E75 F76 G103 M104 Y105 T106 S107 Y152 Y195 F218 Y221 Q222 K8 E75 F76 G103 M104 Y105 T106 S107 Y152 Y195 F218 Y221 Q222 2.1.2.9 F8RC03 25574689 MKLIIAGKNNIAVDVTKWIIKTISDIELYSVCNENDHGNDSFQLSFKKFCIQFNIPIISLEDAYHLEDAIFLSLEFDKIIHPSKFTHNRIFNIHFSYLPAYKGMYTSAWPILNNEQESGVTLHKIDHGIDTGAIIDQQKFPLDIEETAKTLYLKYIKIGTEIVIKNLPALISGNYSIVEQSAIKSSYYSKKSIDYKNLMIDLNKTAHEILQQIRAFTFRDYQLPRIDDIDIFHGEILSSKSLSKPGTILEKNNYHLILSTIDYDIKLYSDNFDEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNFMSTFN 4xcz A 1.50 BS03 T3Q A 2 W305 I309 I310 Y313 H314 N334 K336 T338 M342 Y343 D346 Y380 W305 I309 I310 Y313 H314 N334 K336 T338 M342 Y343 D346 Y380 2.1.2.9 F8RC03 25574689 MKLIIAGKNNIAVDVTKWIIKTISDIELYSVCNENDHGNDSFQLSFKKFCIQFNIPIISLEDAYHLEDAIFLSLEFDKIIHPSKFTHNRIFNIHFSYLPAYKGMYTSAWPILNNEQESGVTLHKIDHGIDTGAIIDQQKFPLDIEETAKTLYLKYIKIGTEIVIKNLPALISGNYSIVEQSAIKSSYYSKKSIDYKNLMIDLNKTAHEILQQIRAFTFRDYQLPRIDDIDIFHGEILSSKSLSKPGTILEKNNYHLILSTIDYDIKLYSDNFDEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNFMSTFN 4xd0 A 1.80 BS02 FON A 1 F76 D77 K78 I79 I80 M104 D126 G128 I129 D130 K190 F76 D77 K78 I79 I80 M104 D126 G128 I129 D130 K190 2.1.2.9 F8RC03 25574689 MKLIIAGKNNIAVDVTKWIIKTISDIELYSVCNENDHGNDSFQLSFKKFCIQFNIPIISLEDAYHLEDAIFLSLEFDKIIHPSKFTHNRIFNIHFSYLPAYKGMYTSAWPILNNEQESGVTLHKIDHGIDTGAIIDQQKFPLDIEETAKTLYLKYIKIGTEIVIKNLPALISGNYSIVEQSAIKSSYYSKKSIDYKNLMIDLNKTAHEILQQIRAFTFRDYQLPRIDDIDIFHGEILSSKSLSKPGTILEKNNYHLILSTIDYDIKLYSDNFDEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNFMSTFN 4xdi A 1.89 BS01 HEM A 1 F41 F42 V45 K49 R52 K53 A56 F57 Y68 L73 S76 H77 L80 M86 F91 V94 A122 I126 F37 F38 V41 K45 R48 K49 A52 F53 Y64 L69 S72 H73 L76 M82 F87 V90 A118 I122 A8JAR4 TAPADSLYSRMGGEAAVEKAVDVFYERIVADPQLAPFFANVDMKKQRRKQVAFMTYVFGGSGAYEGRDLGASHRRLIREQGMNHHHFDLVAAHLDSTLQELGVAQELKAEAMAIVASARPLIFGTGE 4xeu A 1.95 BS01 CA A 1 N215 V216 E223 N207 V208 E215 2.2.1.1 Q9I5Y8 MPSRRERANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDYMQHNPSNPQWANRDRFVLSNGHGSMLIYSLLHLTGYDLGIEDLKNFRQLNSRTPGHPEYGYTAGVETTTGPLGQGIANAVGMALAEKVLAAQFNRDGHAVVDHYTYAFLGDGCMMEGISHEVASLAGTLRLNKLIAFYDDNGGWFTDDTPKRFEAYGWQVIRNVDGHDADEIKTAIDTARKSDQPTLICCKTVIGFADEIAATRAALGWEHAPFEIPAQIYAEWDAKETGAAQEAEWNKRFAAYQAAHPELAAELLRRLKGELPADFAEKAAAYVADVANKGETIASRKASQNALNAFGPLLPELLGGSADTLWKGCKGVSADDAAGNYVFYGVREFGMSAIMNGVALHGGFIPYGATFLIFMEYARNAVRMSALMKQRVLYVFTHDSIGLGEDGPTHQPIEQLASLRLTPNLDTWRPADAVESAVAWKHAIERADGPSALIFSRQNLPHQARDVAQVADIARGGYVLKDCEGEPELILIATGSEVGLAVQAYDKLSEQGRKVRVVSMPCTSVYEQQDESYKQSVLPVEVGARIAIEAAHADYWYKYVGLDGRIIGMTSFGESAPAPALFEHFGFTLDNVLAVAEELL 4xeu A 1.95 BS02 CA A 2 A334 E338 A309 E313 2.2.1.1 Q9I5Y8 MPSRRERANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDYMQHNPSNPQWANRDRFVLSNGHGSMLIYSLLHLTGYDLGIEDLKNFRQLNSRTPGHPEYGYTAGVETTTGPLGQGIANAVGMALAEKVLAAQFNRDGHAVVDHYTYAFLGDGCMMEGISHEVASLAGTLRLNKLIAFYDDNGGWFTDDTPKRFEAYGWQVIRNVDGHDADEIKTAIDTARKSDQPTLICCKTVIGFADEIAATRAALGWEHAPFEIPAQIYAEWDAKETGAAQEAEWNKRFAAYQAAHPELAAELLRRLKGELPADFAEKAAAYVADVANKGETIASRKASQNALNAFGPLLPELLGGSADTLWKGCKGVSADDAAGNYVFYGVREFGMSAIMNGVALHGGFIPYGATFLIFMEYARNAVRMSALMKQRVLYVFTHDSIGLGEDGPTHQPIEQLASLRLTPNLDTWRPADAVESAVAWKHAIERADGPSALIFSRQNLPHQARDVAQVADIARGGYVLKDCEGEPELILIATGSEVGLAVQAYDKLSEQGRKVRVVSMPCTSVYEQQDESYKQSVLPVEVGARIAIEAAHADYWYKYVGLDGRIIGMTSFGESAPAPALFEHFGFTLDNVLAVAEELL 4xiu A 2.50 BS01 NUC B 1 R487 T506 K508 T509 S513 T514 S515 A516 R536 K540 L541 Y545 R573 Q582 N583 I584 P585 V586 R587 H784 D785 R194 T213 K215 T216 S220 T221 S222 A223 R243 K247 L248 Y252 R280 Q289 N290 I291 P292 V293 R294 H491 D492 2.7.7.7 P19821 25537790 LEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 4xiu A 2.50 BS02 NUC C 1 N483 N485 S486 Q489 S543 T544 T569 A570 T571 R573 S575 S576 S577 D578 N580 Y671 G672 M673 S674 R677 R728 K738 S739 E742 R746 M747 N750 Q754 N190 N192 S193 Q196 S250 T251 T276 A277 T278 R280 S282 S283 S284 D285 N287 Y378 G379 M380 S381 R384 R435 K445 S446 E449 R453 M454 N457 Q461 2.7.7.7 P19821 25537790 LEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWLEKTLEEGRRRGYVETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE 4xl8 A 1.65 BS01 MNA A 1 R316 G317 N318 R124 G125 N126 A0MK70 GIQTLWTPPTSNPNCTVYTESDSLLSLCLTKCGAHVLGSVSLTGVAGTMTNMAETSLAIEFTFDDTGKLLHSPLVNNTFSIRQGDSPASNPTYNALAFMPNSTLYARGGSGEPRNNYYVQTYLRGNVQRPITLTVTFNSAATGYSLSFKWTAVVREKFAAPATSFCYITEQ 4xl8 A 1.65 BS02 MNA C 1 G303 N308 Y310 G111 N116 Y118 A0MK70 GIQTLWTPPTSNPNCTVYTESDSLLSLCLTKCGAHVLGSVSLTGVAGTMTNMAETSLAIEFTFDDTGKLLHSPLVNNTFSIRQGDSPASNPTYNALAFMPNSTLYARGGSGEPRNNYYVQTYLRGNVQRPITLTVTFNSAATGYSLSFKWTAVVREKFAAPATSFCYITEQ 4xl8 B 1.65 BS01 MNA A 1 G303 E304 N308 Y310 G101 E102 N106 Y108 A0MK70 IQTLWTPPTSNPNCTVYTESDSLLSLCLTKCGAHVLGSVSLTGVAGTMTNMAETSLAIEFTFDDTGKLLHSPLVNNTFSIRQYNALAFMPNSTLYARGGSGEPRNNYYVQTYLRGNVQRPITLTVTFNSAATGYSLSFKWTAVVREKFAAPATSFCYITEQ 4xl8 B 1.65 BS02 GLU B 1 R299 G300 G301 E304 R97 G98 G99 E102 A0MK70 IQTLWTPPTSNPNCTVYTESDSLLSLCLTKCGAHVLGSVSLTGVAGTMTNMAETSLAIEFTFDDTGKLLHSPLVNNTFSIRQYNALAFMPNSTLYARGGSGEPRNNYYVQTYLRGNVQRPITLTVTFNSAATGYSLSFKWTAVVREKFAAPATSFCYITEQ 4xl8 B 1.65 BS03 ALA B 1 G259 K260 L261 Y285 G66 K67 L68 Y83 A0MK70 IQTLWTPPTSNPNCTVYTESDSLLSLCLTKCGAHVLGSVSLTGVAGTMTNMAETSLAIEFTFDDTGKLLHSPLVNNTFSIRQYNALAFMPNSTLYARGGSGEPRNNYYVQTYLRGNVQRPITLTVTFNSAATGYSLSFKWTAVVREKFAAPATSFCYITEQ 4xl8 C 1.65 BS02 MPD C 1 A250 T328 S331 S339 A66 T132 S135 S143 A0MK70 SGIEGRPYGIQTLWTPPTSNPNCTVYTESDSLLSLCLTKCGAHVLGSVSLTGVAGTMTNMAETSLAIEFTFDDTGKLLHSPLVNNTFSYNALAFMPNSTLYARGGSGEPRNNYYVQTYLRGNVQRPITLTVTFNSAATGYSLSFKWTAVVREKFAAPATSFCYITEQ