3j6q A 3.80 BS01 SAH A 1 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q A 3.80 BS02 SAH A 2 I861 P883 P903 F904 V924 Y992 I861 P883 P903 F904 V924 Y992 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q B 3.80 BS01 SAH B 1 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q B 3.80 BS02 SAH B 2 I861 P883 P903 F904 V924 Y992 I861 P883 P903 F904 V924 Y992 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q C 3.80 BS01 SAH C 1 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q C 3.80 BS02 SAH C 2 I861 P883 P903 F904 V924 Y992 I861 P883 P903 F904 V924 Y992 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q D 3.80 BS01 SAH D 1 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q D 3.80 BS02 SAH D 2 I861 P883 P903 F904 V924 Y992 I861 P883 P903 F904 V924 Y992 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q E 3.80 BS01 SAH E 1 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 S528 G562 A563 E564 E566 D589 R590 V600 I617 N618 S619 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j6q E 3.80 BS02 SAH E 2 I861 P883 P903 F904 V924 Y992 I861 P883 P903 F904 V924 Y992 Q914N6 24690366 MWHYTSINNDTRVALDPKPNQIRTITKPNTVPQLGTDYLYTFNSQRRSHTLRLLGPFQYFNFSETDRGHPLFRLPLKYPSKAIPADELIDNLHSWMRSVHLLHVRSEDNTLRYNWMLGVYARSTNYTTPVGQLVVNAPAILNYSNPQDAFNSVFVALGIDYIDIPITNSNIFDDSSTPYNVRIWHAPTMTEVNHILALMRKSTLVSTHSSWHWNVLHTFHYRSESDMIDHFAAKILEDWRQKEKLDKGALVEADRVIQRLIPLSSSTYVQRLAAIGALYPNEFTENVLDLSRLSTALLQLSDTYYQHANDQLRRLYRRMYNDSRTLYMTQRHQELLLAQITADPNILLYPYTYIFTTIPTSMNYISNTGQGRIKHSLTVTGATEHDTVADIVLGQTGEDVITISMVEPMSIAVEDMYGYVLDTPTRDIWPADEQIEQKGDAVALYDTKTSRALGMFNNTVRIDDLLSPLLSLVYRTYIKGDTMTMTQGSLDHLTLCAAVDSDITFVGNRMIAPLPEGYIPKPMHRNNSTMKMLSLYVALKKLENFATNSYLMAPDTSIILLGAEREPAVNILRRFNRNVSNVRIIGMGDRAVEPNIRVRVPFPIDKNISADFIICDINSYEDQSFESMFSETISVVTTCASAATRALVKINHPSEYMINSVIERLSQLGGVFYHTALLKTASQNPYSYETYIYITPIAAAVRFPFYSNSAMINRYMTAVADDEMPIIPSIHTVIKGHSNTYSPGLFCGCVDVQSAPLALSQLKSYCSEATTWRVDSDDNLVNIIARIDPARIALEFRTRSNTSAYHEYQRYVPNGLGFKVRKTREFRYMHREVTFIHKLMMYALIREQISLTENMTQVVSIGGRNLADISVVPLNMKYVVIDPATRIETLTQEKKNIEVQSRPFQFDAANMDLENNSIYLFIAVIMNEPNGAATPARMQMDKIRNVATAMLTRTNCVAYISFYEAGIITRLDQSTAHKTIRVEEGRLKVANYVPVDTLVEADVTLMLRDIGITHEIIRPSTPELIDACSNYGIRLGSTGGAVLDVFNHYSPVIKLVRS 3j7b A 3.20 BS01 HEM A 1 R71 V72 V73 H74 R111 G130 F131 V145 G146 N147 A157 F160 S216 H217 L298 F333 M349 R353 A356 Y357 T360 H361 R364 R69 V70 V71 H72 R109 G128 F129 V143 G144 N145 A155 F158 S214 H215 L296 F331 M347 R351 A354 Y355 T358 H359 R362 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b A 3.20 BS02 NDP A 1 P150 H193 F197 S200 R202 N212 H234 K236 V301 W302 H304 Q441 T444 F445 V449 P148 H191 F195 S198 R200 N210 H232 K234 V299 W300 H302 Q439 T442 F443 V447 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b A 3.20 BS03 HEM D 1 M60 D64 M58 D62 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b B 3.20 BS01 HEM B 1 R71 V72 V73 H74 R111 S113 G130 F131 A132 V145 G146 N147 A157 F160 S216 H217 L298 M349 R353 A356 Y357 T360 H361 R364 R69 V70 V71 H72 R109 S111 G128 F129 A130 V143 G144 N145 A155 F158 S214 H215 L296 M347 R351 A354 Y355 T358 H359 R362 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b B 3.20 BS02 NDP B 1 H193 F197 S200 R202 H234 K236 V301 W302 P303 H304 Q441 T444 F445 V449 H191 F195 S198 R200 H232 K234 V299 W300 P301 H302 Q439 T442 F443 V447 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b B 3.20 BS03 HEM C 1 M60 D64 M58 D62 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b C 3.20 BS01 HEM B 1 M60 D64 M58 D62 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b C 3.20 BS02 HEM C 1 R71 V72 H74 R111 G130 V145 G146 N147 F160 S216 L298 F333 M349 R353 A356 Y357 T360 H361 R364 R69 V70 H72 R109 G128 V143 G144 N145 F158 S214 L296 F331 M347 R351 A354 Y355 T358 H359 R362 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b C 3.20 BS03 NDP C 1 P150 H193 F197 S200 R202 K236 V301 W302 H304 Q441 T444 F445 V449 P148 H191 F195 S198 R200 K234 V299 W300 H302 Q439 T442 F443 V447 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b D 3.20 BS01 HEM A 1 M60 D64 M58 D62 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b D 3.20 BS02 HEM D 1 R71 V72 V73 H74 R111 G130 F131 V145 G146 N147 A157 F160 S216 H217 L298 F333 M349 R353 A356 Y357 T360 H361 R364 R69 V70 V71 H72 R109 G128 F129 V143 G144 N145 A155 F158 S214 H215 L296 F331 M347 R351 A354 Y355 T358 H359 R362 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3j7b D 3.20 BS03 NDP D 1 P150 H193 F197 R202 N212 H234 K236 V301 W302 P303 H304 Q441 F445 V449 P148 H191 F195 R200 N210 H232 K234 V299 W300 P301 H302 Q439 F443 V447 1.11.1.6 P00432 NRDPASDQMKHWKEQRAAQKPDVLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLRDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNSANDDNVTQVRTFYLKVLNEEQRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQALLDKYNE 3wqt A 2.20 BS01 MG A 1 S13 T38 I41 E209 S10 T35 I38 E202 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqt A 2.20 BS02 ANP A 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G9 S10 S11 S12 K14 G201 E202 D203 V204 G225 E244 K247 H248 G318 S319 N321 L322 E351 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqt B 2.20 BS01 ANP B 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G7 S8 S9 S10 K12 G189 E190 D191 V192 G213 E232 K235 H236 G285 S286 N288 L289 E315 Q6GHQ0 24746687 YVSIDIGSSSVKTIVINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIADIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSIRKPEFSSAISTISSSIAFDELLD 3wqt C 2.20 BS01 ANP C 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G9 S10 S11 S12 K14 G199 E200 D201 V202 G223 E242 K245 H246 G316 S317 N319 L320 E349 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKFGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqt D 2.20 BS01 MG D 1 D48 D50 D41 D43 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSIFTVEQETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqt D 2.20 BS02 ANP D 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G9 S10 S11 S12 K14 G196 E197 D198 V199 G220 E239 K242 H243 G300 S301 N303 L304 E333 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSIFTVEQETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqu A 2.80 BS01 ATP A 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G9 S10 S11 S12 K14 G201 E202 D203 V204 G225 E244 K247 H248 G318 S319 N321 L322 E351 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqu B 2.80 BS01 ATP B 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G9 S10 S11 S12 K14 G202 E203 D204 V205 G226 E245 K248 H249 G319 S320 N322 L323 E352 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqu C 2.80 BS01 ATP C 1 G12 S13 S14 S15 K17 G208 E209 D210 V211 G232 E251 K254 H255 G325 S326 N328 L329 E358 G9 S10 S11 S12 K14 G201 E202 D203 V204 G225 E244 K247 H248 G318 S319 N321 L322 E351 Q6GHQ0 24746687 HYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 3wqu D 2.80 BS01 ATP D 1 G12 S13 S14 S15 K17 G208 E209 V211 G232 E251 K254 H255 G325 S326 N328 L329 G8 S9 S10 S11 K13 G200 E201 V203 G224 E243 K246 H247 G317 S318 N320 L321 Q6GHQ0 24746687 YYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLD 4c7x A 2.29 BS01 MG A 1 D158 N188 I190 D158 N188 I190 2.2.1.1 Q1WQU8 PYDQVDQLGVNTLRTLSIDAIQRANSGHPGLPMGAAPMAYVLWTRHLKINPKTHMNWVNRDRFVLSAGHGSALLYSLAHLAGYDVSMDDLKNFREWKSNTPGHPEYGCTDGVEATTGPLGQGISMAVGMAMAEAHLGKKFNREGYPVMDHYTYALIGDGDLMEGVASEAASLAGHLKLGKLIALYDSNGISLDGKTSASFTENVGARFEAYGWQYILVEDGFNLEEIDKAIVQAKAESDKPTIIEIKTTIGYGSENQGTHKVHGSPLGEEGVAHAKEVYNWNYPPFTVPEEVSQRFKECLQDKGVKAENKWNEMFEAYKKEYSDLAQKFSDGFSNKVPNTLGDILPQYGEDDSIATRAASQKAINALAKEVSSLWGGAADLASSNKTVIAGEGDFQPESYEGRNIWFGVREFGMACAMNGIMLHGGTRIFGSTFFVFSDYLKAAIRLSAIQKLPVIYVLTHDSVAVGKDGPTHEPIEQLASLRTIPNVQVFRPADGNETSAAWKVALETLDKPTILVLSRQNLDTLPISKEKVFDGVEKGGYVVQGAENEADGILIATGSEVGLALKAKEELQKKGKDVIVVSLPSWERFEAQSEEYKNTVIPPELKKRMTIEAGTTYGWAKYAGDHGVMIGIDEFGMSAPSDIVLRELGMSVENIVDKYLE 4c7x A 2.29 BS02 TPP A 1 L31 H69 G117 L119 D158 G159 E163 N188 I190 S191 I250 H263 L31 H69 G117 L119 D158 G159 E163 N188 I190 S191 I250 H263 2.2.1.1 Q1WQU8 PYDQVDQLGVNTLRTLSIDAIQRANSGHPGLPMGAAPMAYVLWTRHLKINPKTHMNWVNRDRFVLSAGHGSALLYSLAHLAGYDVSMDDLKNFREWKSNTPGHPEYGCTDGVEATTGPLGQGISMAVGMAMAEAHLGKKFNREGYPVMDHYTYALIGDGDLMEGVASEAASLAGHLKLGKLIALYDSNGISLDGKTSASFTENVGARFEAYGWQYILVEDGFNLEEIDKAIVQAKAESDKPTIIEIKTTIGYGSENQGTHKVHGSPLGEEGVAHAKEVYNWNYPPFTVPEEVSQRFKECLQDKGVKAENKWNEMFEAYKKEYSDLAQKFSDGFSNKVPNTLGDILPQYGEDDSIATRAASQKAINALAKEVSSLWGGAADLASSNKTVIAGEGDFQPESYEGRNIWFGVREFGMACAMNGIMLHGGTRIFGSTFFVFSDYLKAAIRLSAIQKLPVIYVLTHDSVAVGKDGPTHEPIEQLASLRTIPNVQVFRPADGNETSAAWKVALETLDKPTILVLSRQNLDTLPISKEKVFDGVEKGGYVVQGAENEADGILIATGSEVGLALKAKEELQKKGKDVIVVSLPSWERFEAQSEEYKNTVIPPELKKRMTIEAGTTYGWAKYAGDHGVMIGIDEFGMSAPSDIVLRELGMSVENIVDKYLE 4cit A 1.80 BS01 VO4 A 1 R331 F353 S358 G359 H360 R410 H416 R294 F316 S321 G322 H323 R373 H379 1.11.1.-,1.11.1.8 G0LAH5 25261522 KEEPINITPEELDASIDRVTEIMIHDIFSPPVASRIFAYPNVAAYEIVAATNDNYNSLAGQLNGLTAIPEPDTTKTINYELAAVVAHMELSKRLIFSEDRMESLRDSLYMVWEGKNPVLFSDSKAYGLQVADHIGEWMNKDNYAQTRTMPKDPGRWQPTPPAYMDGIEPHWNKIRPFVLDSAAQFKPVPPPAYSLEEDSAFYKELKEVYDVRNKITEEGDSSEEIQIARFWDCNPYVSKKITPGAHWMGIAKIAARKTNSDFAKTLFAYTKASVAMADAFISCWDEKYRSNLIRPETVINQHIDDSWKPVLQTPPFPEYTSGHSVVSGAASVVLTEVFGDNFSFDDDTEVPYGLPIRSFKSFKQAADEAAISRMYGGIHYRAAIEVGVKQGRDLGTFVVNKLHMLSDKKV 4cit A 1.80 BS02 VO4 A 2 S358 H360 R410 H416 S321 H323 R373 H379 1.11.1.-,1.11.1.8 G0LAH5 25261522 KEEPINITPEELDASIDRVTEIMIHDIFSPPVASRIFAYPNVAAYEIVAATNDNYNSLAGQLNGLTAIPEPDTTKTINYELAAVVAHMELSKRLIFSEDRMESLRDSLYMVWEGKNPVLFSDSKAYGLQVADHIGEWMNKDNYAQTRTMPKDPGRWQPTPPAYMDGIEPHWNKIRPFVLDSAAQFKPVPPPAYSLEEDSAFYKELKEVYDVRNKITEEGDSSEEIQIARFWDCNPYVSKKITPGAHWMGIAKIAARKTNSDFAKTLFAYTKASVAMADAFISCWDEKYRSNLIRPETVINQHIDDSWKPVLQTPPFPEYTSGHSVVSGAASVVLTEVFGDNFSFDDDTEVPYGLPIRSFKSFKQAADEAAISRMYGGIHYRAAIEVGVKQGRDLGTFVVNKLHMLSDKKV 4cit A 1.80 BS03 VO4 A 3 K324 F353 S358 G359 H416 K287 F316 S321 G322 H379 1.11.1.-,1.11.1.8 G0LAH5 25261522 KEEPINITPEELDASIDRVTEIMIHDIFSPPVASRIFAYPNVAAYEIVAATNDNYNSLAGQLNGLTAIPEPDTTKTINYELAAVVAHMELSKRLIFSEDRMESLRDSLYMVWEGKNPVLFSDSKAYGLQVADHIGEWMNKDNYAQTRTMPKDPGRWQPTPPAYMDGIEPHWNKIRPFVLDSAAQFKPVPPPAYSLEEDSAFYKELKEVYDVRNKITEEGDSSEEIQIARFWDCNPYVSKKITPGAHWMGIAKIAARKTNSDFAKTLFAYTKASVAMADAFISCWDEKYRSNLIRPETVINQHIDDSWKPVLQTPPFPEYTSGHSVVSGAASVVLTEVFGDNFSFDDDTEVPYGLPIRSFKSFKQAADEAAISRMYGGIHYRAAIEVGVKQGRDLGTFVVNKLHMLSDKKV 4cit A 1.80 BS04 VO4 A 4 R331 P351 R410 H416 R294 P314 R373 H379 1.11.1.-,1.11.1.8 G0LAH5 25261522 KEEPINITPEELDASIDRVTEIMIHDIFSPPVASRIFAYPNVAAYEIVAATNDNYNSLAGQLNGLTAIPEPDTTKTINYELAAVVAHMELSKRLIFSEDRMESLRDSLYMVWEGKNPVLFSDSKAYGLQVADHIGEWMNKDNYAQTRTMPKDPGRWQPTPPAYMDGIEPHWNKIRPFVLDSAAQFKPVPPPAYSLEEDSAFYKELKEVYDVRNKITEEGDSSEEIQIARFWDCNPYVSKKITPGAHWMGIAKIAARKTNSDFAKTLFAYTKASVAMADAFISCWDEKYRSNLIRPETVINQHIDDSWKPVLQTPPFPEYTSGHSVVSGAASVVLTEVFGDNFSFDDDTEVPYGLPIRSFKSFKQAADEAAISRMYGGIHYRAAIEVGVKQGRDLGTFVVNKLHMLSDKKV 4cno A 1.50 BS01 9PY A 1 S21 E46 R48 M203 R213 F225 Q236 S20 E45 R47 M202 R212 F224 Q231 4.2.1.10 P24670 24957267 KTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKPGQIAVNDLRSVLMILHNA 4cno B 1.50 BS01 9PY B 1 S21 M23 E46 R48 H143 M203 M205 R213 F225 Q236 S20 M22 E45 R47 H142 M202 M204 R212 F224 Q231 4.2.1.10 P24670 24957267 KTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKPGQIAVNDLRSVLMILHNA 4cno C 1.50 BS01 9PY C 1 S21 M23 E46 R48 R213 F225 S21 M23 E46 R48 R213 F225 4.2.1.10 P24670 24957267 MKTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKPGQIAVNDLRSVLMILHNA 4cno D 1.50 BS01 9PY D 1 S21 E46 R48 K170 R213 F225 Q236 S20 E45 R47 K169 R212 F224 Q231 4.2.1.10 P24670 24957267 KTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKPGQIAVNDLRSVLMILHNA 4cp9 A 1.65 BS01 CA A 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 A 1.65 BS02 GAL A 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 A 1.65 BS03 CN8 A 1 Y36 E49 H50 Y36 E49 H50 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 B 1.65 BS01 CA B 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 B 1.65 BS02 GAL B 1 Y36 H50 Q53 D100 T104 N107 Y36 H50 Q53 D100 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 B 1.65 BS03 CN8 B 1 Y36 E49 H50 Q53 Y36 E49 H50 Q53 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 C 1.65 BS01 CA C 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 C 1.65 BS02 GAL C 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 C 1.65 BS03 CN8 C 1 Y36 H50 P51 Q53 Y36 H50 P51 Q53 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 D 1.65 BS01 CA D 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 D 1.65 BS02 GAL D 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cp9 D 1.65 BS03 CN8 D 1 Y36 Q40 E49 H50 P51 Y36 Q40 E49 H50 P51 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb A 1.57 BS01 CA A 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb A 1.57 BS02 GAL A 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb A 1.57 BS03 CN8 A 1 Y36 P38 H50 P51 Y36 P38 H50 P51 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb B 1.57 BS01 CA B 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb B 1.57 BS02 GAL B 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb B 1.57 BS03 CN8 B 1 Y36 H50 P51 Q53 Y36 H50 P51 Q53 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb C 1.57 BS01 CA C 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb C 1.57 BS02 GAL C 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb C 1.57 BS03 CN8 C 1 Y36 H50 Q53 Y36 H50 Q53 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb D 1.57 BS01 CA D 1 Y36 D100 T104 N107 N108 Y36 D100 T104 N107 N108 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb D 1.57 BS02 GAL D 1 Y36 H50 Q53 D100 V101 T104 N107 Y36 H50 Q53 D100 V101 T104 N107 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4cpb D 1.57 BS03 CN8 D 1 Y36 H50 P51 Q53 Y36 H50 P51 Q53 Q05097 25044671 AWKGEVLANNEAGQVTSIIYNPGDVITIVAAGWASYGPTQKWGPQGDREHPDQGLICHDAFCGALVMKIGNSGTIPVNTGLFRWVAPNNVQGAITLIYNDVPGTYGNNSGSFSVNIGKDQS 4csd A 1.35 BS01 MFU A 1 R108 E119 Y128 G130 A131 F132 I152 W167 W172 R104 E115 Y124 G126 A127 F128 I148 W162 W167 Q8XXK6 25044646 MSSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 4csd A 1.35 BS02 MFU A 2 R153 E164 C166 G175 A176 Y177 P196 I198 W213 W218 R149 E159 C161 G170 A171 Y172 P191 I193 W208 W213 Q8XXK6 25044646 MSSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 4csd A 1.35 BS03 MFU A 3 R199 E210 C212 Y219 G221 A222 W258 W263 R194 E205 C207 Y214 G216 A217 W253 W258 Q8XXK6 25044646 MSSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 4csd A 1.35 BS04 MFU A 4 P14 I16 W31 W36 R244 E255 G266 A267 Y268 P15 I17 W32 W37 R239 E250 G261 A262 Y263 Q8XXK6 25044646 MSSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 4csd A 1.35 BS05 MFU A 5 R17 E28 G39 A40 W76 W81 R18 E29 G40 A41 W77 W82 Q8XXK6 25044646 MSSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 4csd A 1.35 BS06 MFU A 6 R62 E73 G84 A85 Y86 P105 I107 W122 W127 R63 E74 G85 A86 Y87 P101 I103 W118 W123 Q8XXK6 25044646 MSSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTAT 4csd B 1.35 BS01 MFU B 1 R17 E28 C30 Y37 G39 A40 W76 W81 R17 E28 C30 Y37 G39 A40 W76 W81 Q8XXK6 25044646 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTA 4csd B 1.35 BS02 MFU B 2 R62 E73 G84 A85 Y86 P105 I107 W122 W127 R62 E73 G84 A85 Y86 P102 I104 W119 W124 Q8XXK6 25044646 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTA 4csd B 1.35 BS03 MFU B 3 R108 E119 Y128 G130 A131 W167 W172 R105 E116 Y125 G127 A128 W164 W169 Q8XXK6 25044646 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTA 4csd B 1.35 BS04 MFU B 4 R153 E164 G175 A176 Y177 P196 I198 W213 W218 R150 E161 G172 A173 Y174 P193 I195 W210 W215 Q8XXK6 25044646 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTA 4csd B 1.35 BS05 MFU B 5 R199 E210 Y219 G221 A222 I243 W258 W263 R196 E207 Y216 G218 A219 I240 W255 W260 Q8XXK6 25044646 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTA 4csd B 1.35 BS06 MFU B 6 P14 I16 W31 W36 R244 E255 G266 A267 Y268 P14 I16 W31 W36 R241 E252 G263 A264 Y265 Q8XXK6 25044646 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTSSTVPGDQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTKGAYTA 4cwa A 2.02 BS01 JA2 A 1 W51 Q93 Y102 G125 G126 D127 E147 V152 D196 S197 S198 D199 Y264 P265 W11 Q53 Y62 G85 G86 D87 E107 V112 D156 S157 S158 D159 Y224 P225 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4cwa C 2.02 BS01 JA2 C 1 W51 Q93 Y102 G126 D127 D196 S197 S198 D199 Y264 P265 I269 W11 Q53 Y62 G86 D87 D156 S157 S158 D159 Y224 P225 I229 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4cxm A 1.75 BS01 MTA A 1 Q72 L88 Q93 G124 G125 D127 C146 E147 I148 D149 V152 D178 A179 D196 S197 S198 P203 A204 L207 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 D109 V112 D138 A139 D156 S157 S158 P163 A164 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4cxm A 1.75 BS02 SPD A 1 V91 I92 Q93 H103 D127 D196 S197 D199 Y264 V51 I52 Q53 H63 D87 D156 S157 D159 Y224 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4cxm B 1.75 BS01 MTA B 1 Q72 L88 G124 G125 D127 C146 E147 I148 D149 V152 D178 A179 D196 S197 S198 P203 A204 T206 L207 Q32 L48 G84 G85 D87 C106 E107 I108 D109 V112 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIEN 4cxm B 1.75 BS02 SPD B 1 V91 I92 Q93 Y102 H103 D127 D196 S197 D199 Y264 V51 I52 Q53 Y62 H63 D87 D156 S157 D159 Y224 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIEN 4cxm C 1.75 BS01 MTA C 1 Q72 L88 Q93 G124 G125 D127 C146 E147 I148 D149 V152 D178 A179 D196 S197 S198 P203 A204 T206 L207 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 D109 V112 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4cxm C 1.75 BS02 SPD C 1 W51 V91 I92 Q93 Y102 H103 D127 D196 S197 D199 Y264 W11 V51 I52 Q53 Y62 H63 D87 D156 S157 D159 Y224 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4d2p A 2.55 BS01 6Z7 A 1 I17 L27 A38 K40 E57 L61 C70 L86 E87 Y88 C89 P90 L139 I149 D150 I17 L27 A38 K40 E54 L58 C67 L83 E84 Y85 C86 P87 L136 I146 D147 2.7.11.1 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2p B 2.55 BS01 6Z7 B 1 I17 L27 A38 K40 E57 L61 C70 L86 E87 Y88 C89 P90 L139 I149 D150 I17 L27 A38 K40 E57 L61 C70 L86 E87 Y88 C89 P90 L139 I149 D150 2.7.11.1 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2p C 2.55 BS01 6Z7 C 1 L27 A38 K40 E57 L61 C70 E87 Y88 C89 P90 L139 I149 D150 F151 L28 A39 K41 E55 L59 C68 E85 Y86 C87 P88 L137 I147 D148 F149 2.7.11.1 Q14680 HMKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKGALAYAAPELIQGKSGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2p D 2.55 BS01 6Z7 A 1 E15 T16 E15 T16 2.7.11.1 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKFIHLDDVTELSVHHRNNRQISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2p D 2.55 BS02 6Z7 D 1 L27 A38 K40 E57 L61 C70 L86 E87 Y88 C89 P90 L139 I149 D150 L27 A38 K40 E57 L61 C70 L86 E87 Y88 C89 P90 L139 I149 D150 2.7.11.1 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKFIHLDDVTELSVHHRNNRQISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2w A 1.92 BS01 NF5 A 1 I17 A38 C70 L86 E87 C89 P90 G92 L139 I149 I17 A38 C67 L83 E84 C86 P87 G89 L136 I146 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCACGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2w B 1.92 BS01 NF5 B 1 I17 L27 A38 C70 L86 E87 Y88 C89 P90 I149 I17 L27 A38 C70 L86 E87 Y88 C89 P90 I149 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2w B 1.92 BS02 NF5 C 1 T16 I17 T16 I17 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2w C 1.92 BS01 NF5 C 1 A38 C70 L86 E87 C89 P90 G92 L139 I149 A38 C66 L82 E83 C85 P86 G88 L135 I145 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2w D 1.92 BS01 NF5 A 1 T16 I17 G18 T16 I17 G18 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKCGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2w D 1.92 BS02 NF5 D 1 L27 A38 L86 E87 Y88 C89 P90 L139 I149 L27 A38 L86 E87 Y88 C89 P90 L139 I149 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKCGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4md1 A 1.73 BS01 SQL A 1 Y26 V213 V217 G218 L221 R225 Y22 V203 V207 G208 L211 R215 P02945 22174747 TGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAFTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDADQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFFGFMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIETLLFMVLDVSAKVGFGLILLRSRAIFGEAE 4md2 A 1.73 BS01 SQL A 1 Y26 V213 V217 G218 L221 R225 Y22 V203 V207 G208 L211 R215 P02945 22174747 TGRPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAFTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDADQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFFGFMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIETLLFMVLDVSAKVGFGLILLRSRAIFGEAE 4mj5 A 2.40 BS01 III C 1 Y7 Y9 Q62 E63 N66 V67 A69 Q70 T73 D77 T80 L81 Y84 Y99 R114 D116 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171 Y7 Y9 Q62 E63 N66 V67 A69 Q70 T73 D77 T80 L81 Y84 Y99 R114 D116 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171 P13746 GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 4mj6 A 2.57 BS01 III C 1 Y7 Y9 M45 Q62 E63 N66 Q70 T73 V76 D77 T80 L81 Y84 Y99 R114 D116 T143 K146 W147 A150 A152 Q155 Q156 Y159 R163 Y7 Y9 M45 Q62 E63 N66 Q70 T73 V76 D77 T80 L81 Y84 Y99 R114 D116 T143 K146 W147 A150 A152 Q155 Q156 Y159 R163 P13746 GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 4mn9 A 1.15 BS01 FE A 1 E23 E58 H61 V106 E23 E58 H61 V106 1.16.3.1 P07798 VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEQSHEEREHAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDKVDPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKE 4mn9 A 1.15 BS02 FE A 2 E58 H61 E103 Q137 E58 H61 E103 Q137 1.16.3.1 P07798 VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEQSHEEREHAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDKVDPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKE 4mn9 A 1.15 BS03 FE A 3 Q54 E58 E103 E136 D140 Q54 E58 E103 E136 D140 1.16.3.1 P07798 VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEQSHEEREHAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDKVDPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKE 4mn9 A 1.15 BS04 FE A 4 Q54 E57 E136 D140 R143 Q54 E57 E136 D140 R143 1.16.3.1 P07798 VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEQSHEEREHAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDKVDPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKE 4mn9 A 1.15 BS05 FE A 5 E53 E57 E53 E57 1.16.3.1 P07798 VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEQSHEEREHAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAALQLEKTVNQALLDLHKLATDKVDPHLCDFLESEYLEEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDKHSVKE 4n0z A 1.70 BS01 CPT A 1 N19 M48 H49 N15 M44 H45 1.20.4.1 Q9NLB2 SEAVKKWVNKIIEENIIAVFAKTECPYCIKAISILKGYNLNSHMHVENIEKNPDMANIQAYLKELTGKSSVPRIFINKDVVGGCDDLVKENDEGKLKERLQKLGLVN 4n10 A 1.87 BS01 CPT A 1 M59 Q63 M55 Q59 1.20.4.1 Q9NLB2 SEAVKKWVNKIIEENIIAVFAKTECPYCIKAISILKGYNLNSHMHVENIEKNPDMANIQAYLKELTGKSSVPRIFINKDVVGGCDDLVKENDEGKLKERLQKLGLVN 4n10 A 1.87 BS02 CPT A 2 M48 H49 M44 H45 1.20.4.1 Q9NLB2 SEAVKKWVNKIIEENIIAVFAKTECPYCIKAISILKGYNLNSHMHVENIEKNPDMANIQAYLKELTGKSSVPRIFINKDVVGGCDDLVKENDEGKLKERLQKLGLVN 4n10 A 1.87 BS03 CPT A 3 M48 H49 V50 M44 H45 V46 1.20.4.1 Q9NLB2 SEAVKKWVNKIIEENIIAVFAKTECPYCIKAISILKGYNLNSHMHVENIEKNPDMANIQAYLKELTGKSSVPRIFINKDVVGGCDDLVKENDEGKLKERLQKLGLVN 4n11 A 1.97 BS01 CPT A 1 K26 E28 C29 V75 K23 E25 C26 V72 1.20.4.1 Q9NLB2 TSEAVKKWVNKIIEENIIAVFAKTECPYCIKAISILKGYNLNSHMHVENIEKNPDMANIQAYLKELTGKSSVPRIFINKDVVGGCDDLVKENDEGKLKERLQKLGLVN 4n46 A 1.39 BS01 COA A 1 C88 L148 H156 R220 S223 L228 L231 F235 A243 S247 G248 M288 A318 F319 H348 C88 L148 H156 R220 S223 L228 L231 F235 A243 S247 G248 M288 A318 F319 H348 2.3.1.9 F0K5D8 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAGLGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSRAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILVTLVHAMQKRDAKKGLATLSIGGGQGTAILLEKC 4n46 B 1.39 BS01 COA B 1 C88 L148 H156 R220 S223 L228 L231 A243 S247 G248 A318 F319 C88 L148 H156 R220 S223 L228 L231 A243 S247 G248 A318 F319 2.3.1.9 F0K5D8 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAGLGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSRAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILVTLVHAMQKRDAKKGLATLSIGGGQGTAILLEKC 4n4y A 2.90 BS01 CU A 1 H233 H282 H283 H225 H274 H275 1.9.3.1 Q5SJ79 SRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMGLMWLSWWMAFIGLVVAALPLLANEATVLYTFYPPLKGHWAFYLGASVFVLSTWVSIYIVLDLWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFGLVEGVDPLVARTLFWWTVHPIVYFWLLPAYAIIYTILPKQAGGKLVSDPMARLAFLLFLLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAAVPMVFNVLAGIVLLVALLLFIYGLFSVLLSRERKPELAEAPLPFAEVIEDRRLVLAMDRIGFWFAVAAILVVLAYGPTLVQLFGHLNPVPGWRLW 4n4y A 2.90 BS02 HEM A 1 L32 G39 P40 Q42 A43 Y46 Y65 L69 H72 N76 A77 L132 Y133 F385 H386 V389 A390 T394 W428 M432 M435 R449 R450 A451 L477 L24 G31 P32 Q34 A35 Y38 Y57 L61 H64 N68 A69 L124 Y125 F377 H378 V381 A382 T386 W420 M424 M427 R441 R442 A443 L469 1.9.3.1 Q5SJ79 SRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMGLMWLSWWMAFIGLVVAALPLLANEATVLYTFYPPLKGHWAFYLGASVFVLSTWVSIYIVLDLWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFGLVEGVDPLVARTLFWWTVHPIVYFWLLPAYAIIYTILPKQAGGKLVSDPMARLAFLLFLLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAAVPMVFNVLAGIVLLVALLLFIYGLFSVLLSRERKPELAEAPLPFAEVIEDRRLVLAMDRIGFWFAVAAILVVLAYGPTLVQLFGHLNPVPGWRLW 4n4y A 2.90 BS03 HAS A 1 Y133 W229 V236 Y237 W239 L240 H282 H283 T302 S309 L310 A313 A317 L320 V350 L353 L354 F356 G360 G363 N366 A367 D372 H376 V381 H384 F385 Q388 V389 R449 Y125 W221 V228 Y229 W231 L232 H274 H275 T294 S301 L302 A305 A309 L312 V342 L345 L346 F348 G352 G355 N358 A359 D364 H368 V373 H376 F377 Q380 V381 R441 1.9.3.1 Q5SJ79 SRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMGLMWLSWWMAFIGLVVAALPLLANEATVLYTFYPPLKGHWAFYLGASVFVLSTWVSIYIVLDLWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFGLVEGVDPLVARTLFWWTVHPIVYFWLLPAYAIIYTILPKQAGGKLVSDPMARLAFLLFLLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAAVPMVFNVLAGIVLLVALLLFIYGLFSVLLSRERKPELAEAPLPFAEVIEDRRLVLAMDRIGFWFAVAAILVVLAYGPTLVQLFGHLNPVPGWRLW 4n4y B 2.90 BS01 CUA B 1 H114 C149 Q151 C153 H157 M160 H112 C147 Q149 C151 H155 M158 1.9.3.1 Q5SJ80 DEHKAHKAILAYEKGWLAFSLAMLFVFIALIAYTLATHTAGVIPAGKLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVEVLPGEVSTVRYTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE 4n8t A 1.90 BS01 HEM A 1 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 F46 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 P69905 24769418 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 4n8t A 1.90 BS02 NO A 1 H58 V62 H58 V62 P69905 24769418 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 4n8t B 1.90 BS01 HEM B 1 T38 F41 F42 H63 K66 A70 L88 L91 H92 L96 V98 N102 F103 L106 L141 T38 F41 F42 H63 K66 A70 L88 L91 H92 L96 V98 N102 F103 L106 L141 P68871 24769418 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 4n8t B 1.90 BS02 NO B 1 H63 V67 H63 V67 P68871 24769418 VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH 4njm A 1.79 BS01 3PG A 1 K9 R55 S56 R75 G77 A78 G79 N102 R217 K263 A266 K11 R57 S58 R77 G79 A80 G81 N104 R219 K265 A268 1.1.1.95 Q76KF5 ASMKIVVITEKPFAENAVKGIREILEKAGHEVVMIEKYKKKEDVIERIKDADGVIVRSDKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRNGVAELCIGMMIFGFRKGFKEGKGRELKDKTLGICGCGYVGKRVKEIAEGIGMKIKVYDPFITTENQVKKIEELFEECQVISLHLPLTKETKGKIGYELIKKLPYGGMICNTARKEIIDEEGLIRIMREREDLIYITDVAPTSKVFNNEFKGRFFATPIKIGAETEESNINAGMAAASQICDFFTNGTVKFQVNKFLE 4njm B 1.79 BS01 3PG B 1 K9 R55 S56 R75 G77 A78 G79 N102 R217 K263 A266 K11 R57 S58 R77 G79 A80 G81 N104 R219 K265 A268 1.1.1.95 Q76KF5 ASMKIVVITEKPFAENAVKGIREILEKAGHEVVMIEKYKKKEDVIERIKDADGVIVRSDKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRNGVAELCIGMMIFGFRKGFKEGKGRELKDKTLGICGCGYVGKRVKEIAEGIGMKIKVYDPFITTENQVKKIEELFEECQVISLHLPLTKETKGKIGYELIKKLPYGGMICNTARKEIIDEEGLIRIMREREDLIYITDVAPTSKVFNNEFKGRFFATPIKIGAETEESNINAGMAAASQICDFFTNGTVKFQVNKFLE 4njo A 2.22 BS01 NAD A 1 A78 N102 V106 G139 C140 G141 Y142 V143 Y161 D162 P163 F164 H187 L188 P189 E193 T194 T215 A216 R217 D241 K263 G265 A266 A80 N104 V108 G141 C142 G143 Y144 V145 Y163 D164 P165 F166 H189 L190 P191 E195 T196 T217 A218 R219 D243 K265 G267 A268 1.1.1.95 Q76KF5 ASMKIVVITEKPFAENAVKGIREILEKAGHEVVMIEKYKKKEDVIERIKDADGVIVRSDKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRNGVAELCIGMMIFGFRKGFKEGKGRELKDKTLGICGCGYVGKRVKEIAEGIGMKIKVYDPFITTENQVKKIEELFEECQVISLHLPLTKETKGKIGYELIKKLPYGGMICNTARKEIIDEEGLIRIMREREDLIYITDVAPTSKVFNNEFKGRFFATPIKIGAETEESNINAGMAAASQICDFFTNGTVKFQVNKFL 4npt A 1.66 BS01 017 A 1 N25 I47 G48 G49 I50 G52 M54 I82 V84 N25 I47 G48 G49 I50 G52 M54 I82 V84 O38896 24738918 PQITLWKRPIVTIKVGGQLREALINTGADDTIFEEISLPGRWKPKLIGGIGGFMKVRQYDQIPIEIAGHKAIGTVLVGPTPINVIGRNMLTQIGATLNF 4nql A 2.30 BS01 III C 1 F403 H404 P405 F156 H157 P158 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVALHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4nql A 2.30 BS02 III C 2 D315 H343 Q346 T347 F349 S351 S352 F403 D68 H96 Q99 T100 F102 S104 S105 F156 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVALHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4nql A 2.30 BS03 ZN A 1 H356 C397 H404 H406 H109 C150 H157 H159 3.4.19.- Q9P371 24787148 FKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLATCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVALHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRV 4oar A 2.41 BS01 III B 1 V730 K734 R740 D745 I748 I751 Q752 W755 V49 K53 R59 D64 I67 I70 Q71 W74 P06401 25204619 QLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRMSEVIAAQLPKILAGMVKPLLFH 4oar A 2.41 BS02 2S0 A 1 L715 L718 N719 L721 G722 E723 Q725 W755 M759 R766 F778 F794 L797 M801 C891 T894 L34 L37 N38 L40 G41 E42 Q44 W74 M78 R85 F97 F113 L116 M120 C210 T213 P06401 25204619 QLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRMSEVIAAQLPKILAGMVKPLLFH 4ob5 H 1.70 BS01 TMO L 1 T97 I100G Q101 T98 I107 Q111 25254371 VQLVQSGAEVKKPGSSVKVSCKASTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAREGTTGGWLGKPIGAFQHWGQGTLVTVS 4ob5 L 1.70 BS01 TMO L 1 Y49 A55 T56 Y51 A57 T58 25254371 MEIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPSTFGQGTKVEIKRLV 4oc7 A 2.50 BS01 III B 1 F277 V280 K284 L294 Q297 V298 L301 R302 F450 E453 F32 V35 K39 L49 Q52 V53 L56 R57 F205 E208 P19793 24821627 DMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4oc7 A 2.50 BS02 2QO A 1 I268 A271 Q275 N306 F313 R316 I324 L326 A327 C432 L436 I23 A26 Q30 N61 F68 R71 I79 L81 A82 C187 L191 P19793 24821627 DMPVERILEAELAVEPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAP 4ogw A 2.05 BS01 NMN A 1 W125 S126 R127 L145 E146 D155 W189 S193 S220 T221 F222 Q226 W81 S82 R83 L101 E102 D111 W145 S149 S176 T177 F178 Q182 3.2.2.5 P28907 25250980 SWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFATSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLDGSRSKIFDKDSTFGSVQVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPED 4ohk A 2.80 BS01 2TE A 1 V28 P29 E32 G181 S183 M213 R215 H504 K514 W517 R518 A521 M522 R525 F526 V28 P29 E32 G179 S181 M211 R213 H483 K493 W496 R497 A500 M501 R504 F505 Q14397 24611879 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4ohk A 2.80 BS02 S6P A 1 G107 G108 T109 S110 E150 E153 S179 V180 G181 A184 S258 R259 H351 K514 G105 G106 T107 S108 E148 E151 S177 V178 G179 A182 S256 R257 H349 K493 Q14397 24611879 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4ohk B 2.80 BS01 2TE B 1 V28 P29 E32 G181 N209 M213 R215 D217 H504 K514 W517 A521 R525 F526 V28 P29 E32 G179 N207 M211 R213 D215 H488 K498 W501 A505 R509 F510 Q14397 24611879 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIGQGPQFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4ohk B 2.80 BS02 S6P B 1 G107 G108 T109 S110 E150 E153 S179 V180 G181 A184 S257 S258 R259 H351 K514 G105 G106 T107 S108 E148 E151 S177 V178 G179 A182 S255 S256 R257 H349 K498 Q14397 24611879 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIGQGPQFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALA 4ojj C 2.32 BS01 MG C 1 E674 I722 E199 I247 P25644 24830408 KFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSSYDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNVSFLTTSKIGLNLITILISRAALIKQDSSRSNILSSPEISTWNEIYDKLFTSLESKIQLIFPPREYNDHIMRLQNDKFMDEAYIWQFLASLALSGKLNHQRIIIDEVRDEIFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLNVMGLVYRDGEISELKHH 4ono A 2.71 BS01 PMK A 1 F125 V127 I128 Q129 F131 G141 Q142 G143 S144 G145 H153 G154 W155 S157 I162 F164 L178 L181 F185 Y188 L189 L192 A215 G216 F229 V270 T273 V274 L277 T281 C282 F285 F109 V111 I112 Q113 F115 G125 Q126 G127 S128 G129 H137 G138 W139 S141 I146 F148 L162 L165 F169 Y172 L173 L176 A194 G195 F208 V249 T252 V253 L256 T260 C261 F264 P29016 PIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDMGGGGEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDSESGTIIFLHQWSKGQFSNEELSDLELLFRFYLFGLTREIQDHASYPFEVQVKAGCELHSGGSPEGFFQVAFNGLDLLSFQQTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNAQGTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWHH 4p69 A 3.30 BS01 AMP A 1 N104 S105 H113 L116 K291 K294 T295 Y298 E376 N95 S96 H104 L107 K274 K277 T278 Y281 E359 2.7.11.5,3.1.3.- Q8X607 GLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYAEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 4p69 A 3.30 BS02 ADP A 1 P316 G317 I318 G320 V322 M323 V325 V334 K336 E416 R417 R418 M419 K461 N462 Y474 D475 A477 P299 G300 I301 G303 V305 M306 V308 V317 K319 E399 R400 R401 M402 K444 N445 Y457 D458 A460 2.7.11.5,3.1.3.- Q8X607 GLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYAEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 4p69 B 3.30 BS01 ADP B 1 G317 I318 G320 M321 V322 M323 V325 V334 K336 E416 R417 M419 D457 K461 N462 Y474 D475 G307 I308 G310 M311 V312 M313 V315 V324 K326 E406 R407 M409 D447 K451 N452 Y464 D465 2.7.11.5,3.1.3.- Q8X607 LELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYAEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 4p69 B 3.30 BS02 AMP B 1 N104 S105 H113 K291 K294 T295 Y298 E376 N94 S95 H103 K281 K284 T285 Y288 E366 2.7.11.5,3.1.3.- Q8X607 LELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYAEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSV 4pm1 A 1.23 BS01 ESZ A 1 K15 L17 A108 L110 S117 T119 K7 L9 A100 L102 S109 T111 P02766 25224922 KCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4pm1 B 1.23 BS01 ESZ B 1 K15 L17 A108 L110 S117 T118 T119 K6 L8 A99 L101 S108 T109 T110 P02766 25224922 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4pme A 1.26 BS01 CUR A 1 K15 L17 P24 S52 A108 L110 S117 T118 T119 K7 L9 P16 S44 A100 L102 S109 T110 T111 P02766 25224922 KCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4pme B 1.26 BS01 FER B 1 K15 L17 A108 L110 S117 T119 K7 L9 A100 L102 S109 T111 P02766 25224922 KCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4pme B 1.26 BS02 FER B 2 N27 Y78 A81 N19 Y70 A73 P02766 25224922 KCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4pmf A 1.35 BS01 CUR A 1 T106 A108 L110 S117 T118 T119 V121 T98 A100 L102 S109 T110 T111 V113 P02766 25224922 KCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4pmf B 1.35 BS01 CUR B 1 K15 L17 T106 A108 L110 S117 T118 T119 V121 K7 L9 T98 A100 L102 S109 T110 T111 V113 P02766 25224922 KCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4pmr A 1.81 BS01 EPE A 1 R70 K79 Q101 D144 Y175 Q213 D227 R34 K43 Q65 D108 Y139 Q177 D189 P95028 25260828 SLGTLLDYAAGVIPASQIRAAGAVGAIRYVSDRRPGGAWMLGKPIQLSEARDLSGNGLKIVSCYQYGKGSTADWLGGASAGVQHARRGSELHAAAGGPTSAPIYASIDDNPSYEQYKNQIVPYLRSWESVIGHQRTGVYANSKTIDWAVNDGLGSYFWQHNWGSPKGYTHPAAHLHQVEKRKVGGVGVDVNQILKPQFGQWA 4pmx A 1.30 BS01 CA A 1 E64 D68 E115 Q118 E43 D47 E94 Q97 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPGT 4pmy A 1.60 BS01 XYP A 1 E55 N56 K59 Q99 W288 W295 E33 N34 K37 Q77 W266 W273 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmy A 1.60 BS02 CA A 1 E64 D68 E115 Q118 E42 D46 E93 Q96 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmy B 1.60 BS01 XYP B 1 E55 N56 K59 Q99 W288 W295 E33 N34 K37 Q77 W266 W273 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmy B 1.60 BS02 CA B 1 E64 D68 E115 Q118 E42 D46 E93 Q96 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmz A 1.40 BS01 CA A 1 E64 D68 E115 Q118 E42 D46 E93 Q96 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmz A 1.40 BS02 BXP A 1 E55 N56 K59 H92 W96 Q99 N137 E138 E254 W288 W295 E33 N34 K37 H70 W74 Q77 N115 E116 E232 W266 W273 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmz B 1.40 BS01 CA B 1 E64 D68 E115 Q118 E42 D46 E93 Q96 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pmz B 1.40 BS02 BXP B 1 E55 N56 K59 H92 W96 Q99 N137 E138 E254 W288 W295 E33 N34 K37 H70 W74 Q77 N115 E116 E232 W266 W273 Q8PET6 APLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHP 4pn2 A 1.42 BS01 CA A 1 E64 D68 E115 Q118 E43 D47 E94 Q97 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPG 4pn2 A 1.42 BS02 XYP A 1 K59 H92 W96 N137 E138 Q221 H223 E254 W288 W295 K38 H71 W75 N116 E117 Q200 H202 E233 W267 W274 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPG 4pn2 A 1.42 BS03 XYP A 2 E55 N56 K59 Q99 W288 W295 E34 N35 K38 Q78 W267 W274 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPG 4pn2 B 1.42 BS01 CA B 1 E64 D68 E115 Q118 E43 D47 E94 Q97 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPG 4pn2 B 1.42 BS02 XYP B 1 K59 H92 W96 N137 E138 Q221 H223 E254 W288 W295 K38 H71 W75 N116 E117 Q200 H202 E233 W267 W274 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPG 4pn2 B 1.42 BS03 XYP B 2 E55 N56 K59 Q99 W288 W295 E34 N35 K38 Q78 W267 W274 Q8PET6 AAPLAATASKFLGCAYGAQQAPGFAQYWNKLTPENGGKWGSVEAVRDQMDWSTLDAAYRFAQANQMPFQMHVMVWGNQQPEWIKTLRPAEQRREIEQWFAAVAQRYPDIALLEVVNEPLNDPPSKADTGGGNYLQALGGNGDSGWEWVLQSFRLARRHFPHTKLMINDYSITSSAQATQKYLQIVRLLQRENLVDAIGVQEHAFETTPEVAVSVHRDNLDALAATGLPIYITEFDLDGPTDAQQLADYKRVFPVFWEHPAVHGITLWGFRPGLWRDKEAAYLIRADGTERPALTWLRDYVAAHPG 4pni A 1.85 BS01 KQQ A 1 L193 G194 F198 V201 A214 M264 T265 M267 N268 G270 D271 L321 R474 T475 L164 G165 F169 V172 A185 M235 T236 M238 N239 G241 D242 L292 R445 T446 2.7.11.14 P28327 25238254 SRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRP 4pnk A 2.56 BS01 KZQ A 1 I197 G198 R199 G200 G203 V205 A218 L222 D272 M274 A321 N322 L324 S334 I168 G169 R170 G171 G174 V176 A189 L193 D243 M245 A292 N293 L295 S305 2.7.11.15 P25098 25238254 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPREVNATKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 4pq7 A 1.85 BS01 ZN A 1 H94 H96 H119 H95 H97 H120 4.2.1.1 P00918 25258712 GMSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASF 4pq7 A 1.85 BS02 IL3 A 1 H94 H96 H119 F131 L198 T199 T200 P202 L204 W209 H95 H97 H120 F131 L198 T199 T200 P202 L204 W209 4.2.1.1 P00918 25258712 GMSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASF 4pq7 A 1.85 BS03 IL3 A 2 H4 W5 H10 H15 W16 D19 H5 W6 H11 H16 W17 D20 4.2.1.1 P00918 25258712 GMSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASF 4pyv A 2.65 BS01 2XF A 1 V30 D32 G34 S35 R74 Y75 T77 P111 F112 F117 V120 D215 G217 A218 S219 V34 D36 G38 S39 R80 Y81 T83 P116 F117 F122 V125 D221 G223 A224 S225 3.4.23.15 P00797 25050166 LGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 4pyv B 2.65 BS01 2XF B 1 Q13 V30 D32 G34 S35 R74 Y75 P111 F112 L114 A115 F117 D215 G217 S219 Q16 V33 D35 G37 S38 R79 Y80 P115 F116 L118 A119 F121 D220 G222 S224 3.4.23.15 P00797 25050166 GNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 4q24 A 2.90 BS01 XVE A 1 G35 C37 M152 A155 V156 N159 Y178 E182 F186 L200 Y202 T206 G26 C28 M143 A146 V147 N150 Y169 E173 F177 L191 Y193 T197 2.3.2.20 Q8GED7 DHGMREEILGDRSRLIRQRGEHALIGICAGNSYFSQKNTVMLLQWAGQRFERTDVVYVDTHIDEMLIADGRSAQEAERSVKRTLKDLRRRLRRSLESVGDHAERFRVRSLSELQETPEYRAVRERTDRAFEEDAEFATACEDMVRAVVMNRPGDGVGISAEHLRAGLNYVLAEAPLFADSPGVFSVPSSVLCYHIDTPITAFLSRRETGFRAAEGQAYVVVRPQ 4qaw A 2.40 BS01 CA A 1 E407 E409 T427 G430 D523 E407 E409 T427 G430 D523 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNVNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGELNS 4qaw A 2.40 BS02 CA A 2 N433 F434 R468 E518 G519 N521 N433 F434 R468 E518 G519 N521 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNVNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGELNS 4qaw B 2.40 BS01 CA B 1 E407 E409 T427 G430 D523 E406 E408 T426 G429 D522 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw B 2.40 BS02 CA B 2 N433 F434 E518 N432 F433 E517 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw C 2.40 BS01 CA C 1 E407 E409 T427 G430 D523 E405 E407 T425 G428 D521 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw C 2.40 BS02 CA C 2 N433 F434 E518 N431 F432 E516 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw D 2.40 BS01 CA D 1 E407 E409 T427 G430 D523 E404 E406 T424 G427 D520 3.2.1.8 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw D 2.40 BS02 CA D 2 N433 F434 R468 E518 N430 F431 R465 E515 3.2.1.8 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw E 2.40 BS01 CA E 1 E407 E409 T427 G430 D523 E402 E404 T422 G425 D518 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw E 2.40 BS02 CA E 2 N433 F434 R468 E518 N521 N428 F429 R463 E513 N516 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw F 2.40 BS01 CA F 1 E407 E409 T427 G430 D523 E404 E406 T424 G427 D520 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw F 2.40 BS02 CA F 2 N433 F434 R468 E518 N430 F431 R465 E515 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw G 2.40 BS01 CA G 1 E407 E409 T427 G430 D523 E404 E406 T424 G427 D520 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw G 2.40 BS02 CA G 2 N433 F434 E518 G519 P520 N521 N430 F431 E515 G516 P517 N518 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKGE 4qaw H 2.40 BS01 CA H 1 E407 E409 T427 G430 D523 E407 E409 T427 G430 D523 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNVNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKG 4qaw H 2.40 BS02 CA H 2 N433 R468 E518 N521 N433 R468 E518 N521 3.2.1.8 H6WCZ0 25202007 ASDANINLSSEKQLIKGFGGINHPAWIGDLTAAQRETAFGNGQNQLGFSILRIYVDDNRNNWYREVATAKRAIEQGALVFASPWNPPSDMVETFNRNGASAKRLKYDKYAAYAQHLNDFVTFMKNNGVDLYAISVQNEPDYAHDWTWWTPQEILRFMKENAGSIQGTRVMAPESFQYLKNISDPILNDPQALANMDILGAHTYGTQIKDFAYPLFKQKGAGKELWMTEVYVPNSDNNSADRWPEALDVSYHMHNAMVEGDFQAYVWWYIRRQYGPMKEDGTISKRGYNMAHFSKFVRPGYVRVDATKNPDTNTYVSAYKGDNKVVIVAINRGTSAASQRFVLQNGNASTVSSYVTDSSRNLASLAPINVSNGAFTAQLPAQSVTTFVANLSGGNSGGGNVNTGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTASAKG 4qb1 A 2.19 BS01 CA A 1 E18 E20 T38 G41 D134 E5 E7 T25 G28 D121 3.2.1.8 H6WCZ0 25202007 GTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb1 A 2.19 BS02 CA A 2 N44 F45 E129 N31 F32 E116 3.2.1.8 H6WCZ0 25202007 GTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb2 A 1.50 BS01 GCU A 1 E31 Y34 N44 R79 W102 E129 N132 E19 Y22 N32 R67 W90 E117 N120 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb2 A 1.50 BS02 CA A 1 E18 E20 T38 G41 D134 E6 E8 T26 G29 D122 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb2 A 1.50 BS03 CA A 2 N44 F45 E129 N32 F33 E117 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb2 A 1.50 BS04 BDP A 1 G14 T15 N60 M61 T62 K66 V138 T139 A140 G2 T3 N48 M49 T50 K54 V126 T127 A128 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb6 A 1.35 BS01 GCU A 1 Y34 N44 R79 W102 E129 N132 Y22 N32 R67 W90 E117 N120 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb6 A 1.35 BS02 CA A 1 N44 F45 E129 N32 F33 E117 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qb6 A 1.35 BS03 CA A 2 E18 E20 T38 G41 D134 E6 E8 T26 G29 D122 3.2.1.8 H6WCZ0 25202007 TGTTYEAETGTTLTDAVVETLYPGYTGSGYVNFNAYTNSAIEWNAINNMTTGTKNVKFRYALESGTRNLDIYVNGTKVLSNEPFTETGSWSTWGEKTIQVAMNSGVNTLRIVTTGTEGPNMDNITVTAS 4qef A 1.47 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECITWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4qef A 1.47 BS02 0NM A 1 H94 H96 H119 L198 T199 W209 H91 H93 H116 L194 T195 W205 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECITWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4qiw A 3.50 BS01 MG A 1 D461 D463 D465 D437 D439 D441 2.7.7.6 Q5JE33 KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRTL 4qiw A 3.50 BS02 ZN A 1 C60 C63 C70 H73 C55 C58 C65 H68 2.7.7.6 Q5JE33 KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRTL 4qiw A 3.50 BS03 ZN A 2 C100 C103 C147 H149 C150 C95 C98 C142 H144 C145 2.7.7.6 Q5JE33 KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRTL 4qiw B 3.50 BS01 ZN B 1 C1065 C1068 C1083 C1086 C1012 C1015 C1030 C1033 2.7.7.6 Q5JE32 PTLTPDELWLVMESYWKEKGFVRQHLDSYNAFIDHGLQDVVNEFGEVVPDIPNFKVKFGKIRIGQPEFQEAQGQRRPLYPMDARIRNLTYSAPLYLEMIPVVNGIEQEPVEVRIGELPIMLKSKACRLYGLSDEELIKLGEDPKDPGGYFIINGSERVIVSIEDLAPNKTLVERDERQNKVVAKVFSYRHGYRALITVERKKDGILYVTIPNVPKPVKFVYVMRALGLLTDKEIVEAVSDDPRIQQVLFDNLEDASDISTQEEALDYIGRLALPGQPKEYRLRRAEHIIDNNLLPHMGVDPENRRAKAYYLGMMALKVLELSLGLRGEDDKDHYANKRLKLAGDLLKDLFRVAFGQLVKDMQYQMTKTYQRENIQRFVRNSIRPDVLSERIEHALATGSWPGGRTGVSQLLDRTNYMSTLSHLRRVTSPLSRDQPHFEARDLHGTHWGRICPTETPEGPNCGLVKNLALMSQITTGIPEREVREYLMKMGVVPIEERRPAPGLYRVYLNGVLIGTVEDGRKLVERIRADRRAGKISDVINVALYEDEEVKEVYINSDDGRVRRPLIVVENGKPKLTREHVEGIKNGTLTWSDLIRMGVIEYLDAEEEENAYVATWPWEVTEEHTHLELMPAAILGIPASLVPYPEHNAAPRNTYGAGMAKQSLGLGWANFRIRVDTRGHLMHYPQVPLVNSRIMKAVGFEDRPAGQNFVVAVLSYHGYNMEDAVIINKASIERGLARSTFFRTYEAEEKRYLGGQKDNFEVPSPNIQGYLGEKYYRHLDEDGLIFPESKVEGKDVLVGRTSPPRRRETSVTVRPSEKGVVDKVIVTETGDGTKLVKVTVRDLRIPELGDKFASRHGQKGVIGLIVPQEDMPWTESGIVPDLIVNPHGIPSRMTVGQLIEAIGGKVASLTGRRVDGTAFIGEPEEKLRKELEELGFKHSGREIMYDGITGRRLEADIFIGVIYYQRLHHMVADKMHARSFGEMERDVLIGHGAAMLLIERLLEESDKTEVWVCESCGHLALEDKRRGKVYCPVCGEDERISKVEMSYAFKLLLDELKAMVIRPSLRLKDR 4qiw N 3.50 BS01 ZN N 1 C10 C44 C45 C10 C44 C45 2.7.7.6 Q5JJC9 MIVPVRCFTCGKVLADKYYEFKKRVEAGEDPGKVLDDLGVERYCCRRTLLSHVELIDQVMVYK 4qiw P 3.50 BS01 ZN P 1 C11 E14 C30 C4 E7 C23 2.7.7.6 Q5JDM8 CAKCGKEVELDLATAREVRCPYCGSKILYKPRPRVARRVKAI 4qiw I 3.50 BS01 MG I 1 D461 D463 D465 D437 D439 D441 2.7.7.6 Q5JE33 KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRT 4qiw I 3.50 BS02 ZN I 1 C60 C63 C70 H73 C55 C58 C65 H68 2.7.7.6 Q5JE33 KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRT 4qiw I 3.50 BS03 ZN I 2 C100 C103 C147 H149 C150 C95 C98 C142 H144 C145 2.7.7.6 Q5JE33 KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVIDPGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGRIKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQFPIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHPEKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNIEAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLKGFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLFNRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQTEEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRYEVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNKLCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLDIIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHEIIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGKVAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRGRVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRTAQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQGKTVDVDRVIVRT 4qiw J 3.50 BS01 ZN J 1 C1065 C1068 C1083 C1086 C1012 C1015 C1030 C1033 2.7.7.6 Q5JE32 PTLTPDELWLVMESYWKEKGFVRQHLDSYNAFIDHGLQDVVNEFGEVVPDIPNFKVKFGKIRIGQPEFQEAQGQRRPLYPMDARIRNLTYSAPLYLEMIPVVNGIEQEPVEVRIGELPIMLKSKACRLYGLSDEELIKLGEDPKDPGGYFIINGSERVIVSIEDLAPNKTLVERDERQNKVVAKVFSYRHGYRALITVERKKDGILYVTIPNVPKPVKFVYVMRALGLLTDKEIVEAVSDDPRIQQVLFDNLEDASDISTQEEALDYIGRLALPGQPKEYRLRRAEHIIDNNLLPHMGVDPENRRAKAYYLGMMALKVLELSLGLRGEDDKDHYANKRLKLAGDLLKDLFRVAFGQLVKDMQYQMTKTYQRENIQRFVRNSIRPDVLSERIEHALATGSWPGGRTGVSQLLDRTNYMSTLSHLRRVTSPLSRDQPHFEARDLHGTHWGRICPTETPEGPNCGLVKNLALMSQITTGIPEREVREYLMKMGVVPIEERRPAPGLYRVYLNGVLIGTVEDGRKLVERIRADRRAGKISDVINVALYEDEEVKEVYINSDDGRVRRPLIVVENGKPKLTREHVEGIKNGTLTWSDLIRMGVIEYLDAEEEENAYVATWPWEVTEEHTHLELMPAAILGIPASLVPYPEHNAAPRNTYGAGMAKQSLGLGWANFRIRVDTRGHLMHYPQVPLVNSRIMKAVGFEDRPAGQNFVVAVLSYHGYNMEDAVIINKASIERGLARSTFFRTYEAEEKRYLGGQKDNFEVPSPNIQGYLGEKYYRHLDEDGLIFPESKVEGKDVLVGRTSPPRRRETSVTVRPSEKGVVDKVIVTETGDGTKLVKVTVRDLRIPELGDKFASRHGQKGVIGLIVPQEDMPWTESGIVPDLIVNPHGIPSRMTVGQLIEAIGGKVASLTGRRVDGTAFIGEPEEKLRKELEELGFKHSGREIMYDGITGRRLEADIFIGVIYYQRLHHMVADKMHARSFGEMERDVLIGHGAAMLLIERLLEESDKTEVWVCESCGHLALEDKRRGKVYCPVCGEDERISKVEMSYAFKLLLDELKAMVIRPSLRLKDR 4qiw V 3.50 BS01 ZN V 1 C7 T9 C10 C44 C45 C7 T9 C10 C44 C45 2.7.7.6 MIVPVRCFTCGKVLADKYYEFKKRVEAGEDPGKVLDDLGVERYCCRRTLLSHVELIDQVMVYK 4qiw W 3.50 BS01 ZN W 1 C11 E14 C30 C4 E7 C23 2.7.7.6 Q5JDM8 CAKCGKEVELDLATAREVRCPYCGSKILYKPRPRVARRVKAI 4qm6 A 1.50 BS01 NUC C 1 S37 N38 R41 Q51 T52 T54 F58 H62 T80 Q83 A86 R123 Y128 V129 H133 S38 N39 R42 Q52 T53 T55 F59 H63 T81 Q84 A87 R124 Y129 V130 H134 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm6 A 1.50 BS02 GTP A 1 S17 G18 S19 G20 K21 S22 T23 N38 R116 R120 R123 S18 G19 S20 G21 K22 S23 T24 N39 R117 R121 R124 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm6 B 1.50 BS01 NUC D 1 S37 N38 R41 Q51 T52 T54 F58 H62 T80 Q83 A86 R123 V125 Y128 V129 H133 S38 N39 R42 Q52 T53 T55 F59 H63 T81 Q84 A87 R124 V126 Y129 V130 H134 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm6 B 1.50 BS02 GTP B 1 S17 G18 S19 G20 K21 S22 T23 N38 R116 R120 R123 S18 G19 S20 G21 K22 S23 T24 N39 R117 R121 R124 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm7 A 1.80 BS01 NUC C 1 S37 R41 Q51 T54 F58 H62 A79 T80 Q83 A86 R123 Y128 V129 H133 S38 R42 Q52 T55 F59 H63 A80 T81 Q84 A87 R124 Y129 V130 H134 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSDFCRGLMSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm7 A 1.80 BS02 GTP A 1 S17 G18 S19 G20 K21 S22 T23 R116 R120 R123 S18 G19 S20 G21 K22 S23 T24 R117 R121 R124 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSDFCRGLMSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm7 B 1.80 BS01 GTP B 1 S17 G18 S19 G20 K21 S22 T23 R116 R120 R123 S18 G19 S20 G21 K22 S23 T24 R117 R121 R124 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSDFCRGLMSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qm7 B 1.80 BS02 MG B 1 S22 R123 S23 R124 A3DJ38 25266383 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSDFCRGLMSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4qmg A 2.70 BS01 III F 1 P39 G41 G42 P43 R87 K88 K93 F244 A246 E247 F250 F251 S254 R255 L256 Q258 R259 D260 H279 N281 L287 F293 R324 P23 G25 G26 P27 R71 K72 K77 F222 A224 E225 F228 F229 S232 R233 L234 Q236 R237 D238 H257 N259 L265 F271 R302 Q7KZF4 25242325 PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRRTPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPT 4qmg B 2.70 BS01 III G 1 P39 G42 P43 R87 K88 I91 G92 K93 F244 A246 E247 F250 S254 R255 L256 Q258 R259 D260 H279 N281 L287 E291 F293 R324 R327 P23 G26 P27 R71 K72 I75 G76 K77 F220 A222 E223 F226 S230 R231 L232 Q234 R235 D236 H255 N257 L263 E267 F269 R300 R303 Q7KZF4 25242325 PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRRNNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRDGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPT 4qmg C 2.70 BS01 III H 1 Q38 P39 G42 P43 R87 K88 K93 F244 E247 F250 F251 S254 R255 Q258 R259 D260 H279 N281 E291 F293 R324 Q22 P23 G26 P27 R63 K64 K69 F217 E220 F223 F224 S227 R228 Q231 R232 D233 H252 N254 E264 F266 R297 Q7KZF4 25242325 PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRADTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREAETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPT 4qmg D 2.70 BS01 III I 1 G41 G42 P43 R87 K88 G92 K93 F244 A246 E247 F250 S254 R255 L256 Q258 R259 D260 H279 N281 L287 F293 R324 G25 G26 P27 R71 K72 G76 K77 F223 A225 E226 F229 S233 R234 L235 Q237 R238 D239 H258 N260 L266 F272 R303 Q7KZF4 25242325 PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRRETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAP 4qmg E 2.70 BS01 III J 1 P39 G41 G42 P43 R87 K88 I91 K93 F244 A246 E247 F250 F251 S254 R255 L256 Q258 R259 D260 H279 N281 E291 F293 R324 R327 P23 G25 G26 P27 R71 K72 I75 K77 F220 A222 E223 F226 F227 S230 R231 L232 Q234 R235 D236 H255 N257 E267 F269 R300 R303 Q7KZF4 25242325 PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRRNNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRRGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPT 4qtn A 2.80 BS01 NNR A 1 C53 V54 V57 Q99 Q171 M174 W182 W185 N189 Y217 C52 V53 V56 Q98 Q170 M173 W181 W184 N188 Y216 D2ZZC1 GSLAWWKRELFGGWTHFEAVWLLMFLGIQAVVFVFNPDSWLASVAAVTGILCVVFVGKGKISNYLFGLISVSLYAYVSYTFKLYGEMMLNLLVYVPVQFVGFAMWRKHMALGETAETEEVKAKALTVRQWLLVVAASVVGTSVYIEWLHHLGSALPTLDGVTVVVSIVAQVLMILRYREQWALWIVVNILTISLWAVAWFKNGETSLPLLLMYVMYLCNSVYGYINWTKLVKRHS 4qtn B 2.80 BS01 NNR B 1 V54 Q99 Q171 M174 W182 W185 N189 Y217 V53 Q98 Q170 M173 W181 W184 N188 Y216 D2ZZC1 GSLAWWKRELFGGWTHFEAVWLLMFLGIQAVVFVFNPDSWLASVAAVTGILCVVFVGKGKISNYLFGLISVSLYAYVSYTFKLYGEMMLNLLVYVPVQFVGFAMWRKHMALGETAETEEVKAKALTVRQWLLVVAASVVGTSVYIEWLHHLGSALPTLDGVTVVVSIVAQVLMILRYREQWALWIVVNILTISLWAVAWFKNGETSLPLLLMYVMYLCNSVYGYINWTKLVKRHS 4qtn C 2.80 BS01 NNR C 1 C53 V54 V57 V72 Y95 Q99 Q171 M174 W182 W185 N189 C52 V53 V56 V71 Y94 Q98 Q170 M173 W181 W184 N188 D2ZZC1 GSLAWWKRELFGGWTHFEAVWLLMFLGIQAVVFVFNPDSWLASVAAVTGILCVVFVGKGKISNYLFGLISVSLYAYVSYTFKLYGEMMLNLLVYVPVQFVGFAMWRKHMALGETAETEEVKAKALTVRQWLLVVAASVVGTSVYIEWLHHLGSALPTLDGVTVVVSIVAQVLMILRYREQWALWIVVNILTISLWAVAWFKNGETSLPLLLMYVMYLCNSVYGYINWTKLVKRHSGQ 4quv A 2.74 BS01 NDP A 1 T254 N316 K319 R323 L345 L346 L347 W352 H357 N359 Y360 D399 C403 K406 Y407 W411 Y414 T220 N282 K285 R289 L311 L312 L313 W318 H323 N325 Y326 D365 C369 K372 Y373 W377 Y380 1.3.1.70 G4SW86 FSWLVLMIALPPLVYYLWICVTYYQGELVFTSDAAAWRRFWSHVAPPTWHAAGLYAAWFLGQAALQVWAPGPTVQGMKLPDGSRLDYRMNGIFSFLFTLAVVFGLVTMGWLDATVLYDQLGPLLTVVNIFTFVFAGFLYFWGPFYDYFMGTALNPRIGSLDLKLFCEARPGMIFWLLMNLSMAAKQYELHGTVTVPMLLVVGFQSFYLIDYFIHEEAVLTTWDIKHEKFGWMLCWGDLVWLPFTYTLQAQYLVHHTHDLPVWGIIAIVALNLAGYAIFRGANIQKHHFRRDPNRIVWGKPAKYIKTKQGSLLLTSGWWGIARHMNYFGDLMIALSWCLPAAFGSPIPYFHIVYFTILLLHREKRDDAMCLAKYGEDWLQYRKKVPWRIVPKIY 4quv B 2.74 BS01 NDP B 1 K319 R323 L345 L346 L347 W352 H357 N359 Y360 D399 C403 K406 Y407 Y414 K281 R285 L307 L308 L309 W314 H319 N321 Y322 D361 C365 K368 Y369 Y376 1.3.1.70 G4SW86 SWLVLMIALPPLVYYLWICVTYYQGELVFTSDAAAWRRFWSHVAPPTWHAAGLYAAWFLGQAALQVWAPGPTVQGMKLPDGSRLDYRMNGIFSFLFTLAVVFGLVTMGWLDATVLYDQLGPLLTVVNIFTFVFAGFLYPFYDYFMGTALNPRIGSLDLKLFCEARPGMIFWLLMNLSMAAKQYELHGTVTVPMLLVVGFQSFYLIDYFIHEEAVLTTWDIKHEKFGWMLCWGDLVWLPFTYTLQAQYLVHHTHDLPVWGIIAIVALNLAGYAIFRGANIQKHHFRRDPNRIVWGKPAKYIKTKQGSLLLTSGWWGIARHMNYFGDLMIALSWCLPAAFGSPIPYFHIVYFTILLLHREKRDDAMCLAKYGEDWLQYRKKVPWRIVPKIY 4r28 C 3.06 BS01 NUC X 1 Y31 A32 Q33 E65 A66 G67 I68 R88 S90 W101 D103 Y114 F115 G116 D117 K119 K173 G174 Y24 A25 Q26 E58 A59 G60 I61 R81 S83 W94 D96 Y107 F108 G109 D110 K112 K166 G167 A3PUQ5 IAWAASAEVANKPRLVFVGDELRYAQGANQRDVELDGFVNYHWLTSPGGLGLPKVMLEAGINAPAEVVGPDRSRRALIAIRSSPWKAGHETNPWHDEFDLDHGHVRYFGDHKPSTVGLPGETKGNRLLLEAARLHAGTTREERLLAPPLFLFRAVTVHRAGRAVVKGHVEFCGAAIIERLEHVVQRDPETGRSFPNLSLDLAVVSGGEIDGVDFRWIDDRRNAALAAGETLRHAPESWIRWVRQGRLAIPGIRRRVLASAVQSSKEQQPASGSAEAATLQTLYKFYDGRKHAFELLASRVAAEVFRESGARYKEGWLSRSSGDGGVDFIGRIDMGSLKASTPVVVLGQAKCIQPTSSVSPEQVARVVARLRRGWIGVYVTTGSFSRQAQVEIIDDQYPVVLIAGGTLAATVRRMVQANYGGDLDALLASTVDEYGAAVTHRRPEEVISL 4r28 C 3.06 BS02 NUC Y 1 P60 K61 M63 E65 P71 A72 R82 R169 P53 K54 M56 E58 P64 A65 R75 R162 A3PUQ5 IAWAASAEVANKPRLVFVGDELRYAQGANQRDVELDGFVNYHWLTSPGGLGLPKVMLEAGINAPAEVVGPDRSRRALIAIRSSPWKAGHETNPWHDEFDLDHGHVRYFGDHKPSTVGLPGETKGNRLLLEAARLHAGTTREERLLAPPLFLFRAVTVHRAGRAVVKGHVEFCGAAIIERLEHVVQRDPETGRSFPNLSLDLAVVSGGEIDGVDFRWIDDRRNAALAAGETLRHAPESWIRWVRQGRLAIPGIRRRVLASAVQSSKEQQPASGSAEAATLQTLYKFYDGRKHAFELLASRVAAEVFRESGARYKEGWLSRSSGDGGVDFIGRIDMGSLKASTPVVVLGQAKCIQPTSSVSPEQVARVVARLRRGWIGVYVTTGSFSRQAQVEIIDDQYPVVLIAGGTLAATVRRMVQANYGGDLDALLASTVDEYGAAVTHRRPEEVISL 4r2a A 1.59 BS01 NUC B 1 R336 F349 R351 E354 R357 H358 I361 R375 S378 R379 H382 H386 T389 R407 R413 R2 F15 R17 E20 R23 H24 I27 R41 S44 R45 H48 H52 T55 R73 R79 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2a A 1.59 BS02 NUC C 1 R351 D353 R360 R379 D381 R407 S408 D409 K412 R17 D19 R26 R45 D47 R73 S74 D75 K78 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2a A 1.59 BS03 ZN A 1 C340 C345 H358 H362 C6 C11 H24 H28 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2a A 1.59 BS04 ZN A 2 C370 C373 H386 H390 C36 C39 H52 H56 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2a A 1.59 BS05 ZN A 3 C398 C401 H414 H418 C64 C67 H80 H84 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2c A 1.89 BS01 NUC B 1 R347 R351 E354 R357 I361 R375 F377 S378 R379 H382 H386 T389 R407 E410 R413 R13 R17 E20 R23 I27 R41 F43 S44 R45 H48 H52 T55 R73 E76 R79 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2c A 1.89 BS02 NUC C 1 R351 S352 D353 R379 D381 S408 D409 K412 R17 S18 D19 R45 D47 S74 D75 K78 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2c A 1.89 BS03 ZN A 1 C340 C345 H358 H362 C6 C11 H24 H28 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2c A 1.89 BS04 ZN A 2 C370 C373 H386 H390 C36 C39 H52 H56 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2c A 1.89 BS05 ZN A 3 C398 C401 H414 H418 C64 C67 H80 H84 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR 4r2d A 2.09 BS01 NUC B 1 R336 R347 R351 E354 R357 I361 R375 F377 S378 R379 H382 H386 T389 R407 E410 R413 R2 R13 R17 E20 R23 I27 R41 F43 S44 R45 H48 H52 T55 R73 E76 R79 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQ 4r2d A 2.09 BS02 NUC C 1 R351 D353 R360 R379 D381 R407 S408 D409 K412 R17 D19 R26 R45 D47 R73 S74 D75 K78 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQ 4r2d A 2.09 BS03 ZN A 1 C340 C345 H358 H362 C6 C11 H24 H28 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQ 4r2d A 2.09 BS04 ZN A 2 C370 C373 H386 H390 C36 C39 H52 H56 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQ 4r2d A 2.09 BS05 ZN A 3 C398 C401 H414 H418 C64 C67 H80 H84 P18146 25258363 ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQ 4r2e A 1.84 BS01 NUC B 1 R362 F364 R366 Q369 R372 H373 R376 R390 R394 H397 H401 T404 R424 R430 R13 F15 R17 Q20 R23 H24 R27 R41 R45 H48 H52 T55 R75 R81 P19544 25258363 EKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2e A 1.84 BS02 NUC C 1 R366 S367 D368 R394 D396 K399 R424 S425 D426 V429 R17 S18 D19 R45 D47 K50 R75 S76 D77 V80 P19544 25258363 EKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2e A 1.84 BS03 ZN A 1 C355 C360 H373 H377 C6 C11 H24 H28 P19544 25258363 EKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2e A 1.84 BS04 ZN A 2 C385 C388 H401 H405 C36 C39 H52 H56 P19544 25258363 EKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2e A 1.84 BS05 ZN A 3 C413 C418 H431 H435 C64 C69 H82 H86 P19544 25258363 EKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2p A 1.79 BS01 NUC B 1 R362 F364 R366 Q369 R372 H373 R376 R390 F392 S393 R394 H397 H401 T404 R424 R430 R14 F16 R18 Q21 R24 H25 R28 R42 F44 S45 R46 H49 H53 T56 R76 R82 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2p A 1.79 BS02 NUC C 1 R366 S367 D368 R372 F383 R394 S395 D396 K399 R424 S425 D426 V429 R18 S19 D20 R24 F35 R46 S47 D48 K51 R76 S77 D78 V81 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2p A 1.79 BS03 ZN A 1 C355 C360 H373 H377 C7 C12 H25 H29 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2p A 1.79 BS04 ZN A 2 C385 C388 H401 H405 C37 C40 H53 H57 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2p A 1.79 BS05 ZN A 3 C413 C418 H431 H435 C65 C70 H83 H87 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2q A 1.54 BS01 NUC B 1 R362 F364 R366 Q369 R372 H373 R376 R390 S393 R394 H397 H401 T404 K409 R424 E427 R430 R14 F16 R18 Q21 R24 H25 R28 R42 S45 R46 H49 H53 T56 K61 R76 E79 R82 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2q A 1.54 BS02 NUC C 1 R366 D368 D396 K399 R424 S425 D426 R18 D20 D48 K51 R76 S77 D78 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2q A 1.54 BS03 ZN A 1 C355 C360 H373 H377 C7 C12 H25 H29 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2q A 1.54 BS04 ZN A 2 C385 C388 H401 H405 C37 C40 H53 H57 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2q A 1.54 BS05 ZN A 3 C413 C418 H431 H435 C65 C70 H83 H87 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2r A 2.09 BS01 NUC B 1 R362 F364 R366 Q369 R372 H373 R376 R390 F392 R394 H397 H401 T404 R424 R430 R14 F16 R18 Q21 R24 H25 R28 R42 F44 R46 H49 H53 T56 R76 R82 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2r A 2.09 BS02 NUC C 1 R366 S367 D368 D396 K399 F411 R424 S425 D426 V429 R18 S19 D20 D48 K51 F63 R76 S77 D78 V81 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2r A 2.09 BS03 ZN A 1 C355 C360 H373 H377 C7 C12 H25 H29 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2r A 2.09 BS04 ZN A 2 C385 C388 H401 H405 C37 C40 H53 H57 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2r A 2.09 BS05 ZN A 3 C413 C418 H431 H435 C65 C70 H83 H87 P19544 25258363 SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 4r2s A 2.49 BS01 NUC B 1 K351 R362 F364 R366 P369 R372 H373 R376 K381 R390 F392 S393 R394 H397 H401 T404 R424 E427 R430 K3 R14 F16 R18 P21 R24 H25 R28 K33 R42 F44 S45 R46 H49 H53 T56 R76 E79 R82 P19544 25258363 SEKPYQCDFKDCERRFSRSDPLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2s A 2.49 BS02 NUC C 1 R366 R394 D396 R424 S425 D426 R18 R46 D48 R76 S77 D78 P19544 25258363 SEKPYQCDFKDCERRFSRSDPLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2s A 2.49 BS03 ZN A 1 C355 C360 H373 H377 C7 C12 H25 H29 P19544 25258363 SEKPYQCDFKDCERRFSRSDPLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2s A 2.49 BS04 ZN A 2 C385 C388 H401 H405 C37 C40 H53 H57 P19544 25258363 SEKPYQCDFKDCERRFSRSDPLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r2s A 2.49 BS05 ZN A 3 C413 C418 H431 H435 C65 C70 H83 H87 P19544 25258363 SEKPYQCDFKDCERRFSRSDPLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR 4r63 A 1.85 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 Y296 H28 S221 K222 G223 E224 T225 K226 Y263 Y288 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r63 A 1.85 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 H135 M236 R254 D256 S98 G99 G101 P102 S103 A104 H129 M228 R246 D248 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r63 A 1.85 BS03 NUC D 1 K35 A38 Y39 P63 G64 G66 K68 I69 K29 A32 Y33 P57 G58 G60 K62 I63 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r64 A 2.20 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 K295 Y296 H25 S220 K221 G222 E223 T224 K225 Y262 K286 Y287 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r64 A 2.20 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 K234 R254 D256 S95 G96 G98 P99 S100 A101 K225 R245 D247 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r64 A 2.20 BS03 NUC D 1 K35 A38 Y39 G64 G66 T67 K68 I69 K26 A29 Y30 G55 G57 T58 K59 I60 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r65 A 1.95 BS01 NUC T 1 H34 N133 S229 K230 G231 E232 T233 K234 Y271 K280 R283 L287 T292 I293 N294 E295 Y296 H25 N124 S220 K221 G222 E223 T224 K225 Y262 K271 R274 L278 T283 I284 N285 E286 Y287 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r65 A 1.95 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 D192 R254 D256 Y271 S95 G96 G98 P99 S100 A101 D183 R245 D247 Y262 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r65 A 1.95 BS03 NUC D 1 H34 K35 A38 Y39 P63 G64 G66 T67 K68 I69 H25 K26 A29 Y30 P54 G55 G57 T58 K59 I60 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r65 A 1.95 BS04 DUP A 1 G179 S180 R183 S188 G189 D190 D192 Y271 F272 T273 G274 D276 N279 G170 S171 R174 S179 G180 D181 D183 Y262 F263 T264 G265 D267 N270 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r65 A 1.95 BS05 MG A 1 D190 D192 D181 D183 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r65 A 1.95 BS06 MG A 2 D190 D192 D256 D181 D183 D247 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIALIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r66 A 2.25 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 Y296 H25 S220 K221 G222 E223 T224 K225 Y262 Y287 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r66 A 2.25 BS02 NUC P 1 V103 S104 G105 I106 G107 P108 S109 A110 H135 K234 R254 R258 V94 S95 G96 I97 G98 P99 S100 A101 H126 K225 R245 R249 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r66 A 2.25 BS03 NUC D 1 K35 A38 Y39 G64 G66 K68 I69 K26 A29 Y30 G55 G57 K59 I60 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r66 A 2.25 BS04 DUP A 1 G179 S180 R183 S188 G189 D190 D192 Y271 F272 G274 N279 G170 S171 R174 S179 G180 D181 D183 Y262 F263 G265 N270 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r66 A 2.25 BS05 MN A 1 D190 D192 D181 D183 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r66 A 2.25 BS06 MN A 2 D190 D192 D181 D183 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4r6w A 1.59 BS01 PC A 1 Q18 Y19 Y27 I36 A128 Y160 Y175 R179 Y181 K247 Q10 Y11 Y19 I28 A120 Y152 Y167 R171 Y173 K239 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6w A 1.59 BS02 SAH A 1 L14 Y19 I36 S37 G63 G65 D85 I86 C87 I90 N109 D110 I111 R127 A128 A129 H132 L6 Y11 I28 S29 G55 G57 D77 I78 C79 I82 N101 D102 I103 R119 A120 A121 H124 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6w B 1.59 BS01 PC B 1 Q18 Y19 Y27 I36 A128 Y160 Y175 R179 Y181 K247 Q10 Y11 Y19 I28 A120 Y152 Y167 R171 Y173 K239 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6w B 1.59 BS02 SAH B 1 L14 Y19 I36 S37 G63 G65 D85 I86 C87 N109 D110 I111 R127 A128 A129 H132 L6 Y11 I28 S29 G55 G57 D77 I78 C79 N101 D102 I103 R119 A120 A121 H124 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6x A 2.55 BS01 OPE A 1 Q18 Y27 I36 Y160 Y175 R179 Y181 K247 Q10 Y19 I28 Y152 Y167 R171 Y173 K239 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6x A 2.55 BS02 SAH A 1 L14 Y19 Y35 I36 S37 G63 S64 G65 D85 I86 C87 I90 N109 D110 I111 R127 A128 A129 H132 L6 Y11 Y27 I28 S29 G55 S56 G57 D77 I78 C79 I82 N101 D102 I103 R119 A120 A121 H124 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6x B 2.55 BS01 OPE B 1 Q18 Y27 I36 Y160 Y175 R179 Y181 K247 Q10 Y19 I28 Y152 Y167 R171 Y173 K239 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r6x B 2.55 BS02 SAH B 1 L14 Y19 Y35 I36 S37 G63 S64 G65 D85 I86 C87 D110 I111 R127 A128 A129 H132 L133 L6 Y11 Y27 I28 S29 G55 S56 G57 D77 I78 C79 D102 I103 R119 A120 A121 H124 L125 Q6T755 SDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENNFDLIYSRAAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISLDDGWSRKIKDSKRKMQRWGYFKATKN 4r7y A 2.70 BS01 ADP A 1 A1289 I1290 Y1291 P1330 G1331 V1332 A1333 K1334 S1335 Q1336 H1850 I1851 A296 I297 Y298 P337 G338 V339 A340 K341 S342 Q343 H490 I491 3.6.4.12 Q8U3I4 25262915 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7y A 2.70 BS02 ZN A 1 H144 C149 C171 C174 H138 C143 C165 C168 3.6.4.12 Q8U3I4 25262915 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7y B 2.70 BS01 ADP B 1 A1289 I1290 Y1291 Y1293 P1330 G1331 A1333 K1334 S1335 V1847 I1851 A296 I297 Y298 Y300 P337 G338 A340 K341 S342 V487 I491 3.6.4.12 Q8U3I4 25262915 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7y B 2.70 BS02 ZN B 1 H144 C149 C171 C174 H138 C143 C165 C168 3.6.4.12 Q8U3I4 25262915 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z A 3.80 BS01 ADP A 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z A 3.80 BS02 MG A 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z B 3.80 BS01 ADP B 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z B 3.80 BS02 MG B 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z C 3.80 BS01 ADP C 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z C 3.80 BS02 MG C 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z C 3.80 BS03 ADP D 1 A922 E926 A273 E277 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z D 3.80 BS01 ADP D 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z D 3.80 BS02 MG D 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z E 3.80 BS01 ADP E 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z E 3.80 BS02 MG E 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z F 3.80 BS01 ADP F 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z F 3.80 BS02 MG F 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z F 3.80 BS03 ADP G 1 A922 E926 A273 E277 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z G 3.80 BS01 ADP G 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z G 3.80 BS02 MG G 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z H 3.80 BS01 ADP H 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z H 3.80 BS02 MG H 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z I 3.80 BS01 ADP I 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z I 3.80 BS02 MG I 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z J 3.80 BS01 ADP J 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z J 3.80 BS02 MG J 1 S335 E760 S73 E125 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z J 3.80 BS03 ADP K 1 A922 E926 A273 E277 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z K 3.80 BS01 ADP K 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z K 3.80 BS02 MG K 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z L 3.80 BS01 ADP L 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z L 3.80 BS02 MG L 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z M 3.80 BS01 ADP M 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z M 3.80 BS02 MG M 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z M 3.80 BS03 ADP N 1 A922 E926 A273 E277 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z N 3.80 BS01 ADP N 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z N 3.80 BS02 MG N 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z O 3.80 BS01 ADP O 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z O 3.80 BS02 MG O 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z P 3.80 BS01 ADP I 1 A922 E926 A273 E277 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z P 3.80 BS02 ADP P 1 I290 Y291 Y293 P330 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 Y31 P68 G69 A71 K72 S73 Q74 V212 I216 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4r7z P 3.80 BS03 MG P 1 S335 E760 S73 E125 Q8U3I4 25262915 PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAM 4ra4 A 2.63 BS01 3KZ A 1 G346 F350 V353 A366 T401 M417 E418 V420 D467 N468 D481 G15 F19 V22 A35 T70 M86 E87 V89 D136 N137 D150 2.7.11.13 L7RSM7 25254961 DRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHP 4ra5 A 2.61 BS01 3L0 A 1 L386 G387 K388 V394 A407 T442 M458 E459 L461 D508 L511 A521 D522 F664 F668 L13 G14 K15 V21 A34 T69 M85 E86 L88 D135 L138 A148 D149 F291 F295 2.7.11.13 Q04759 25254961 KLKIEDFELHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNEFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGMERLISH 4ra5 B 2.61 BS01 3L0 B 1 L386 G387 K388 F391 V394 A407 T442 M458 E459 L461 D465 D508 L511 D522 L12 G13 K14 F17 V20 A33 T68 M84 E85 L87 D91 D134 L137 D148 2.7.11.13 Q04759 25254961 LKIEDFELHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNEFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDPRLSRALINSMDQNMFRNFSFMNPGM 4rbm A 1.75 BS01 CA A 1 D313 F482 E491 D85 F254 E263 3.4.22.47 Q51817 DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKVLLIAGADYSWNSQVGQPTIKYGMQYYYNQEHGYTDVYNYLKAPYTGCYSHLNTGVSFANYTAHGSETAWADPLLTTSQLKALTNKDKYFLAIGNCCITAQFDYVQPCFGEVITRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVMPYRAMPKTNTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATVSMTKQITENGNYDVVITRSNYLPVIKQIQV 4rbm A 1.75 BS02 CA A 2 D337 D339 F341 E343 D109 D111 F113 E115 3.4.22.47 Q51817 DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKVLLIAGADYSWNSQVGQPTIKYGMQYYYNQEHGYTDVYNYLKAPYTGCYSHLNTGVSFANYTAHGSETAWADPLLTTSQLKALTNKDKYFLAIGNCCITAQFDYVQPCFGEVITRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVMPYRAMPKTNTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATVSMTKQITENGNYDVVITRSNYLPVIKQIQV 4rbm A 1.75 BS03 HIS A 1 E379 M599 E151 M371 3.4.22.47 Q51817 DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKVLLIAGADYSWNSQVGQPTIKYGMQYYYNQEHGYTDVYNYLKAPYTGCYSHLNTGVSFANYTAHGSETAWADPLLTTSQLKALTNKDKYFLAIGNCCITAQFDYVQPCFGEVITRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVMPYRAMPKTNTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATVSMTKQITENGNYDVVITRSNYLPVIKQIQV 4rbm A 1.75 BS04 AZI A 1 H234 D339 H6 D111 3.4.22.47 Q51817 DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKVLLIAGADYSWNSQVGQPTIKYGMQYYYNQEHGYTDVYNYLKAPYTGCYSHLNTGVSFANYTAHGSETAWADPLLTTSQLKALTNKDKYFLAIGNCCITAQFDYVQPCFGEVITRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVMPYRAMPKTNTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATVSMTKQITENGNYDVVITRSNYLPVIKQIQV 4rbm A 1.75 BS05 AZI A 2 H234 G235 L237 W558 H6 G7 L9 W330 3.4.22.47 Q51817 DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKVLLIAGADYSWNSQVGQPTIKYGMQYYYNQEHGYTDVYNYLKAPYTGCYSHLNTGVSFANYTAHGSETAWADPLLTTSQLKALTNKDKYFLAIGNCCITAQFDYVQPCFGEVITRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVMPYRAMPKTNTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATVSMTKQITENGNYDVVITRSNYLPVIKQIQV 4rbm A 1.75 BS06 CKC A 1 T442 A443 H444 G445 N475 C477 S511 W513 D516 T214 A215 H216 G217 N247 C249 S283 W285 D288 3.4.22.47 Q51817 DVYTDHGDLYNTPVRMLVVAGAKFKEALKPWLTWKAQKGFYLDVHYTDEAEVGTTNASIKAFIHKKYNDGLAASAAPVFLALVGDTDVISGEKGKKTKKVTDLYYSAVDGDYFPEMYTFRMSASSPEELTNIIDKVLMYEKATMPDKSYLEKVLLIAGADYSWNSQVGQPTIKYGMQYYYNQEHGYTDVYNYLKAPYTGCYSHLNTGVSFANYTAHGSETAWADPLLTTSQLKALTNKDKYFLAIGNCCITAQFDYVQPCFGEVITRVKEKGAYAYIGSSPNSYWGEDYYWSVGANAVFGVQPTFEGTSMGSYDATFLEDSYNTVNSIMWAGNLAATHAGNIGNITHIGAHYYWEAYHVLGDGSVMPYRAMPKTNTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATVSMTKQITENGNYDVVITRSNYLPVIKQIQV 4rch A 2.30 BS01 GLC A 1 S151 F152 P153 T168 K169 N204 D205 I225 N231 E256 E290 S138 F139 P140 T155 K156 N191 D192 I212 N218 E243 E277 2.7.1.2 P35557 25203462 TLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKAC 4rch A 2.30 BS02 3LZ A 1 V62 R63 S64 E96 G97 Q98 M210 I211 Y214 M235 L451 V452 V455 V49 R50 S51 E83 G84 Q85 M197 I198 Y201 M222 L438 V439 V442 2.7.1.2 P35557 25203462 TLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKAC 4rdv A 2.08 BS01 NFQ A 1 H58 Q61 F78 R82 M85 Y121 H206 R209 E235 L298 H57 Q60 F77 R81 M84 Y120 H205 R208 E234 L297 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGEL 4rdv A 2.08 BS02 ZN A 1 H56 H58 H232 D320 H55 H57 H231 D319 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGEL 4rdv B 2.08 BS01 NFQ B 1 H58 Q61 F78 R82 Y121 H206 R209 H232 E235 L298 H57 Q60 F77 R81 Y120 H205 R208 H231 E234 L297 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdv B 2.08 BS02 ZN B 1 H56 H58 H232 D320 H55 H57 H231 D319 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdv C 2.08 BS01 NFQ C 1 H58 Q61 F78 R82 Y121 H206 R209 H232 E235 L298 D320 H57 Q60 F77 R81 Y120 H205 R208 H231 E234 L297 D319 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdv C 2.08 BS02 ZN C 1 H56 H58 H232 D320 H55 H57 H231 D319 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdv D 2.08 BS01 NFQ D 1 H58 Q61 F78 R82 Y121 H206 R209 E235 L298 H57 Q60 F77 R81 Y120 H205 R208 E234 L297 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdv D 2.08 BS02 ZN D 1 H56 H58 H232 D320 H55 H57 H231 D319 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdw A 1.59 BS01 ZN A 1 H56 H58 H232 D320 H55 H57 H231 D319 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rdw A 1.59 BS02 NGQ A 1 H58 Q61 F78 W81 R82 M85 Y121 H206 R209 E235 L298 H57 Q60 F77 W80 R81 M84 Y120 H205 R208 E234 L297 Q9HU77 SAIFAERALLPEGWARNVRFEISADGVLAEIRPDANADGAERLGGAVLPGMPNLHSHAFQRAMAGLAEVAGNPNDSFWTWRELMYRMVARLSPEQIEVIACQLYIEMLKAGYTAVAEFHYVHHDLDGRSYADPAELSLRISRAASAAGIGLTLLPVLYSHAGFGGQPASEGQRRFINGSEAYLELLQRLRAPLEAAGHSLGLCFHSLRAVTPQQIATVLAAGHDDLPVHIHIAEQQKEVDDCQAWSGRRPLQWLYENVAVDQRWCLVHATHADPAEVAAMARSGAVAGLCLSTEANLGDGIFPATDFLAQGGRLGIGSDSHVSLSVVEELRWLEYGQRLRDRKRNRLYRDDQPMIGRTLYDAALAGGAQALGQPIGSLAVGRRADLLVLDGNDPYLASAEGDALLNRWLFAGGDRQVRDVMVAGRWVVRDGRHAGEERSARAFVQVLGELL 4rfb A 1.93 BS01 FUC A 1 E202 K205 E165 K168 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb A 1.93 BS02 GAL A 1 E202 K205 R211 E165 K168 R174 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb A 1.93 BS03 SIA A 1 L161 K197 F198 Y199 T200 R211 D214 L124 K160 F161 Y162 T163 R174 D177 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb B 1.93 BS01 FUC B 1 E202 K205 E163 K166 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDEEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb B 1.93 BS02 GAL B 1 E202 K205 R211 E163 K166 R172 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDEEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb B 1.93 BS03 SIA B 1 L161 K197 F198 Y199 T200 R211 D214 L122 K158 F159 Y160 T161 R172 D175 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDEEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb C 1.93 BS01 FUC C 1 E202 K205 E162 K165 Q2G1S5 NYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb C 1.93 BS02 GAL C 1 E202 Q208 E162 Q168 Q2G1S5 NYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb C 1.93 BS03 SIA C 1 L161 K197 F198 Y199 T200 R211 D214 L121 K157 F158 Y159 T160 R171 D174 Q2G1S5 NYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb D 1.93 BS01 FUC D 1 E202 K205 E164 K167 Q2G1S5 NYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb D 1.93 BS02 GAL D 1 E202 K205 E164 K167 Q2G1S5 NYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfb D 1.93 BS03 SIA D 1 L161 K197 F198 Y199 T200 R211 D214 L123 K159 F160 Y161 T162 R173 D176 Q2G1S5 NYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rfq A 2.40 BS01 SAM A 1 P78 E89 P90 I168 W169 T172 G195 C196 G197 Q216 D217 Y218 G268 E269 W270 S293 T295 Y301 P10 E21 P22 I81 W82 T85 G108 C109 G110 Q129 D130 Y131 G168 E169 W170 S193 T195 Y201 2.1.1.- O95568 AAPSQDTDSPLSAASSSRNLEPHGKQPSLRAAKEHAMPKDLKKMLENKVIETLPGFQHVKLSVVKTILLKENFPYEGGLKIWECTFDLLAYFTKAKVKFAGKKVLDLGCGSGLLGITAFKGGSKEIHFQDYNSMVIDEVTLPNVVANSTLEDRKPKVTQLYKCRFFSGEWSEFCKLVLSSEKLFVKYDLILTSETIYNPDYYSNLHQTFLRLLSKNGRVLLASKAHYFGVGGGVHLFQKFVEERDVFKTRILKIIDEGLKRFIIEITFKF 4rgt A 2.00 BS01 GAL A 1 E202 Q208 E162 Q168 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKESEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rgt A 2.00 BS02 SIA A 1 L161 K197 F198 Y199 T200 R211 D214 L121 K157 F158 Y159 T160 R171 D174 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKESEKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rgt B 2.00 BS01 GAL B 1 E202 Q208 R211 E162 Q168 R171 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDSKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4rgt B 2.00 BS02 SIA B 1 L161 K197 F198 Y199 T200 R211 D214 L121 K157 F158 Y159 T160 R171 D174 Q2G1S5 HNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDSKSKDSKFKITKEEISLKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK 4tn0 A 2.40 BS01 ZN A 1 E227 T266 D427 H428 E23 T62 D223 H224 A3ZEY5 MFKTIANDAYRHTKKLLVLVVGETARAANYSLGGYTKNDTNFYTKKDNVVFFDNFSSCGTATAVSLPCMFSISKRENYSSSEFQENAMDVLYKTGVDAAWFDNNSGGCKGVCDRLAYKQKLSSDLDENLLIPFKEKLNHLSDQNIIVLHLQGSHGPTYYKRYPSEFKKFTPTCDTNELSKCDSEALINTYDNTLLYTDYLLSEIIKLLKEQKSYESSLFYLSDHGESLGENGIYLHGMPYAIAPSYQTHIPAIFWSNDEKLMNLAKEHKGLKLSQDNLFSTLLGYFNVKTSVYEPEYDLLNPKLKANP 4tn0 B 2.40 BS01 ZN B 1 E227 T266 D427 H428 E22 T61 D222 H223 A3ZEY5 MFKTIANDAYHTKKLLVLVVGETARAANYSLGGYTKNDTNFYTKKDNVVFFDNFSSCGTATAVSLPCMFSISKRENYSSSEFQENAMDVLYKTGVDAAWFDNNSGGCKGVCDRLAYKQKLSSDLDENLLIPFKEKLNHLSDQNIIVLHLQGSHGPTYYKRYPSEFKKFTPTCDTNELSKCDSEALINTYDNTLLYTDYLLSEIIKLLKEQKSYESSLFYLSDHGESLGENGIYLHGMPYAIAPSYQTHIPAIFWSNDEKLMNLAKEHKGLKLSQDNLFSTLLGYFNVKTSVYEPEYDLLNPKLKANP 4tn0 C 2.40 BS01 ZN C 1 E227 T266 D427 H428 E23 T62 D223 H224 A3ZEY5 MFKTIANDAYRHTKKLLVLVVGETARAANYSLGGYTKNDTNFYTKKDNVVFFDNFSSCGTATAVSLPCMFSISKRENYSSSEFQENAMDVLYKTGVDAAWFDNNSGGCKGVCDRLAYKQKLSSDLDENLLIPFKEKLNHLSDQNIIVLHLQGSHGPTYYKRYPSEFKKFTPTCDTNELSKCDSEALINTYDNTLLYTDYLLSEIIKLLKEQKSYESSLFYLSDHGESLGENGIYLHGMPYAIAPSYQTHIPAIFWSNDEKLMNLAKEHKGLKLSQDNLFSTLLGYFNVKTSVYEPEYDLLNPKLKANP 4tvk A 2.30 BS01 TJH A 1 W84 Y121 E199 F288 F290 F330 F331 Y334 W432 M436 I439 H440 G441 Y442 W83 Y120 E198 F287 F289 F329 F330 Y333 W431 M435 I438 H439 G440 Y441 3.1.1.7 P04058 25259726 DHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNAT 4twc A 1.70 BS01 37J A 1 I23 A36 Y56 M82 E83 L85 G86 P87 D91 L92 L135 I148 L293 I22 A35 Y55 M81 E82 L84 G85 P86 D90 L91 L134 I147 L291 2.7.11.1,2.7.11.26 P48730 22331384 ELRVGNRYRLGNKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF 4twc B 1.70 BS01 37J B 1 A36 Y56 M82 E83 L85 G86 P87 D91 L92 L135 L293 A36 Y56 M82 E83 L85 G86 P87 D91 L92 L135 L290 2.7.11.1,2.7.11.26 P48730 22331384 MELRVGNRYRLGNKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKARQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF 4twr A 1.90 BS01 NAD A 1 G10 A12 G13 F14 I15 D34 N35 L36 S37 T38 G39 G52 D53 I54 F75 A76 A77 S78 N94 S117 S118 Y143 K147 Y170 F171 N172 A173 H186 G8 A10 G11 F12 I13 D32 N33 L34 S35 T36 G37 G50 D51 I52 F73 A74 A75 S76 N92 S115 S116 Y141 K145 Y168 F169 N170 A171 H184 5.1.3.2 Q2YKG6 ANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIRTAAPHFGLEVR 4twr A 1.90 BS02 ZN A 1 E184 H186 E189 H191 E182 H184 E187 H189 5.1.3.2 Q2YKG6 ANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIRTAAPHFGLEVR 4u0g A 3.20 BS01 III c 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA 4u0g A 3.20 BS02 III i 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA 4u0g A 3.20 BS03 ZIL A 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA 4u0g B 3.20 BS01 III c 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K22 L23 E26 I28 T60 Y62 Q88 V90 L92 M112 L114 L191 R194 3.4.21.92 P9WPC3 YILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g B 3.20 BS02 III d 1 L61 V62 S65 T92 Y95 R97 L48 V49 S52 T79 Y82 R84 3.4.21.92 P9WPC3 YILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g B 3.20 BS03 ZIL B 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G68 G69 F70 T71 H122 P124 S125 I144 M147 M151 3.4.21.92 P9WPC3 YILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g C 3.20 BS01 III d 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g C 3.20 BS02 III e 1 L61 V62 S65 T92 Y95 L47 V48 S51 T78 Y81 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g C 3.20 BS03 ZIL C 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g D 3.20 BS01 III e 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKL 4u0g D 3.20 BS02 III f 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKL 4u0g D 3.20 BS03 ZIL D 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKL 4u0g E 3.20 BS01 III f 1 K35 L36 E39 I41 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA 4u0g E 3.20 BS02 III g 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA 4u0g E 3.20 BS03 ZIL E 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSA 4u0g F 3.20 BS01 III g 1 K35 L36 E39 I41 Y75 Q101 V103 L105 M125 L204 R207 K21 L22 E25 I27 Y61 Q87 V89 L91 M111 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g F 3.20 BS02 III h 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g F 3.20 BS03 ZIL F 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g G 3.20 BS01 III i 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g G 3.20 BS02 III h 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g G 3.20 BS03 ZIL G 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g H 3.20 BS01 ZIL H 1 G69 S70 I71 S98 M99 F102 H123 P125 L126 F143 M150 G53 S54 I55 S82 M83 F86 H107 P109 L110 F127 M134 3.4.21.92 P9WPC5 TDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHII 4u0g I 3.20 BS01 ZIL I 1 G69 S70 I71 S98 M99 F102 H123 P125 L126 F143 M150 G51 S52 I53 S80 M81 F84 H105 P107 L108 F125 M132 3.4.21.92 P9WPC5 SVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHII 4u0g J 3.20 BS01 ZIL J 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 F143 G52 S53 I54 S81 M82 F85 H106 Q107 P108 L109 F126 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITR 4u0g K 3.20 BS01 ZIL K 1 G69 S70 I71 S98 M99 F102 H123 P125 L126 G127 F143 M150 G51 S52 I53 S80 M81 F84 H105 P107 L108 G109 F125 M132 3.4.21.92 P9WPC5 SVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHII 4u0g L 3.20 BS01 ZIL L 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 F143 I146 G52 S53 I54 S81 M82 F85 H106 Q107 P108 L109 F126 I129 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0g M 3.20 BS01 ZIL M 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 G127 F143 I146 M150 G51 S52 I53 S80 M81 F84 H105 Q106 P107 L108 G109 F125 I128 M132 3.4.21.92 P9WPC5 SVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0g N 3.20 BS01 ZIL N 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 G127 F143 M150 G52 S53 I54 S81 M82 F85 H106 Q107 P108 L109 G110 F126 M133 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0g O 3.20 BS01 III j 1 L61 V62 S65 Y95 R97 L47 V48 S51 Y81 R83 3.4.21.92 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g O 3.20 BS02 III p 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L190 R193 3.4.21.92 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g O 3.20 BS03 ZIL O 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g P 3.20 BS01 III j 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRK 4u0g P 3.20 BS02 III k 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRK 4u0g P 3.20 BS03 ZIL P 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRK 4u0g Q 3.20 BS01 III k 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKL 4u0g Q 3.20 BS02 III l 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKL 4u0g Q 3.20 BS03 ZIL Q 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKL 4u0g R 3.20 BS01 III l 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g R 3.20 BS02 III m 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g R 3.20 BS03 ZIL R 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g S 3.20 BS01 III m 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g S 3.20 BS02 III n 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g S 3.20 BS03 ZIL S 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g T 3.20 BS01 III n 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g T 3.20 BS02 III o 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g T 3.20 BS03 ZIL T 1 G81 G82 F83 T84 H135 P137 S138 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g U 3.20 BS01 III o 1 K35 L36 E39 I41 T73 Y75 Q101 V103 L105 M125 L127 L204 R207 K21 L22 E25 I27 T59 Y61 Q87 V89 L91 M111 L113 L190 R193 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g U 3.20 BS02 III p 1 L61 V62 S65 T92 Y95 R97 L47 V48 S51 T78 Y81 R83 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g U 3.20 BS03 ZIL U 1 G81 G82 F83 T84 H135 P137 S138 Q153 I157 M160 M164 G67 G68 F69 T70 H121 P123 S124 Q139 I143 M146 M150 3.4.21.92 P9WPC3 ILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLS 4u0g V 3.20 BS01 ZIL V 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 G127 F143 I146 G52 S53 I54 S81 M82 F85 H106 Q107 P108 L109 G110 F126 I129 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITR 4u0g W 3.20 BS01 ZIL W 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 G127 F143 G52 S53 I54 S81 M82 F85 H106 Q107 P108 L109 G110 F126 3.4.21.92 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITR 4u0g X 3.20 BS01 ZIL X 1 G69 S70 I71 S98 M99 H123 Q124 P125 L126 F143 I146 G52 S53 I54 S81 M82 H106 Q107 P108 L109 F126 I129 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITR 4u0g Y 3.20 BS01 ZIL Y 1 G69 S70 I71 S98 M99 H123 Q124 P125 L126 F143 I146 M150 G52 S53 I54 S81 M82 H106 Q107 P108 L109 F126 I129 M133 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0g Z 3.20 BS01 ZIL Z 1 G69 S70 I71 S98 M99 H123 Q124 P125 L126 G127 F143 I146 M150 N154 G53 S54 I55 S82 M83 H107 Q108 P109 L110 G111 F127 I130 M134 N138 3.4.21.92 P9WPC5 TDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0g a 3.20 BS01 ZIL a 1 G69 S70 I71 S98 M99 F102 H123 Q124 P125 L126 G127 F143 I146 G52 S53 I54 S81 M82 F85 H106 Q107 P108 L109 G110 F126 I129 3.4.21.92 P9WPC5 DSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0g b 3.20 BS01 ZIL b 1 G69 S70 I71 S98 M99 F102 H123 P125 L126 G127 F143 I146 M150 G53 S54 I55 S82 M83 F86 H107 P109 L110 G111 F127 I130 M134 3.4.21.92 P9WPC5 TDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIIT 4u0i A 2.00 BS01 0LI A 1 L595 A621 V622 K623 E640 L644 L647 I653 V654 T670 E671 Y672 C673 C788 I789 H790 R791 L799 I808 C809 D810 F811 L31 A54 V55 K56 E73 L77 L80 I86 V87 T103 E104 Y105 C106 C152 I153 H154 R155 L163 I172 C173 D174 F175 2.7.10.1 P10721 25239608 GNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSLALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTN 4u6r A 2.50 BS01 3E4 A 1 V586 A597 K599 E612 L616 Y628 I640 I642 E643 C645 A646 E651 L695 S710 D711 F712 V26 A37 K39 E52 L56 Y68 I80 I82 E83 C85 A86 E91 L135 S150 D151 F152 2.7.11.1 O75460 TSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGTLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH 4u79 A 2.23 BS01 3EL A 1 V78 A91 K93 R107 E111 I124 L144 M146 M149 D150 A151 Q155 L206 D207 V33 A46 K48 R62 E66 I79 L99 M101 M104 D105 A106 Q110 L161 D162 2.7.11.24 P53779 VDNQFYSVEVGDSTFTVLKRYQNLKPIGSGGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPLDEREHTIEEWKELIYKEVMN 4uc0 A 2.40 BS01 HPA A 1 A108 A109 G110 F184 E185 V201 G202 M203 T226 N227 A98 A99 G100 F174 E175 V191 G192 M193 T216 N217 2.4.2.1 B9JYS2 PAVDLLIDRLNGLLPRIAIVLGSGLGGLVDEVENAVRIPFADIPGFPKELVAGLFAGQPIIMLAGRVHYYEEGDAAAMRLPIETLASLGVTTLILTNAAGSLRADMPPGSVMQLIDHINFSGHNPLIGETGDGRFVGMTQAYDGELAEAMRRAADAEDISLSSGVYMWFSGPSFETPAEIRMARTLGADAVGMSTVPEVILARFFGLKVAAASVITNYGAGMTDMAPIGGRRLVAILKRMIVDGGAD 4uma A 1.76 BS01 MN A 1 C63 H270 E304 D324 C47 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma A 1.76 BS02 GZ3 A 1 C63 R94 Y96 K99 P100 G165 A166 R167 K188 R236 H270 D324 C47 R78 Y80 K83 P84 G149 A150 R151 K172 R220 H254 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma B 1.76 BS01 MN B 1 C63 H270 E304 D324 C47 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma B 1.76 BS02 GZ3 B 1 C63 R94 Y96 K99 P100 G165 A166 R167 K188 R236 H270 C47 R78 Y80 K83 P84 G149 A150 R151 K172 R220 H254 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma C 1.76 BS01 MN C 1 C63 H270 E304 D324 C48 H255 E289 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma C 1.76 BS02 GZ3 C 1 C63 R94 Y96 K99 P100 G165 A166 R167 K188 R236 H270 D324 C48 R79 Y81 K84 P85 G150 A151 R152 K173 R221 H255 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma D 1.76 BS01 MN D 1 C63 H270 E304 D324 C48 H255 E289 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4uma D 1.76 BS02 GZ3 D 1 C63 R94 Y96 K99 G165 A166 R167 K188 R236 H270 D324 C48 R79 Y81 K84 G150 A151 R152 K173 R221 H255 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb A 2.17 BS01 MN A 1 C63 H270 E304 D324 C48 H255 E289 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARA 4umb A 2.17 BS02 0V5 A 1 C63 R94 Y96 K99 P100 E145 G165 A166 R167 K188 R236 H270 E304 D324 C48 R79 Y81 K84 P85 E130 G150 A151 R152 K173 R221 H255 E289 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARA 4umb B 2.17 BS01 MN B 1 C63 H270 E304 D324 C47 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb B 2.17 BS02 0V5 B 1 C63 R94 Y96 K99 P100 E145 G165 A166 R167 K188 R236 H270 E304 C47 R78 Y80 K83 P84 E129 G149 A150 R151 K172 R220 H254 E288 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb C 2.17 BS01 MN C 1 C63 H270 E304 D324 C47 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb C 2.17 BS02 0V5 C 1 C63 R94 Y96 K99 P100 E145 G165 A166 R167 K188 R236 H270 E304 C47 R78 Y80 K83 P84 E129 G149 A150 R151 K172 R220 H254 E288 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb D 2.17 BS01 MN D 1 C63 R94 H270 E304 D324 C47 R78 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb D 2.17 BS02 0V5 D 1 C63 R94 Y96 K99 P100 E145 G165 A166 R167 K188 R236 H270 E304 C47 R78 Y80 K83 P84 E129 G149 A150 R151 K172 R220 H254 E288 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umc A 2.34 BS01 MN A 1 C63 H270 E304 D324 C48 H255 E289 D309 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umc A 2.34 BS02 PEQ A 1 C63 R94 Y96 K99 G165 A166 R167 K188 R236 H270 E304 C48 R79 Y81 K84 G150 A151 R152 K173 R221 H255 E289 2.5.1.54 Q9K169 25245459 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umc B 2.34 BS01 MN B 1 C63 H270 E304 D324 C47 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARA 4umc B 2.34 BS02 PEQ B 1 C63 R94 Y96 K99 G165 A166 R167 K188 R236 H270 E304 C47 R78 Y80 K83 G149 A150 R151 K172 R220 H254 E288 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARA 4umc C 2.34 BS01 MN C 1 C63 H270 E304 D324 C49 H256 E290 D310 2.5.1.54 Q9K169 25245459 VKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umc C 2.34 BS02 PEQ C 1 C63 R94 Y96 K99 G165 A166 R167 K188 R236 H270 E304 C49 R80 Y82 K85 G151 A152 R153 K174 R222 H256 E290 2.5.1.54 Q9K169 25245459 VKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umc D 2.34 BS01 MN D 1 C63 K99 H270 E304 D324 C47 K83 H254 E288 D308 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umc D 2.34 BS02 PEQ D 1 C63 R94 Y96 K99 G165 A166 R167 K188 R236 H270 E304 C47 R78 Y80 K83 G149 A150 R151 K172 R220 H254 E288 2.5.1.54 Q9K169 25245459 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4ump A 2.30 BS01 5QM A 1 I17 A38 E57 L61 C70 L86 E87 C89 L139 I149 D150 I17 A38 E54 L58 C67 L83 E84 C86 L136 I146 D147 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4ump B 2.30 BS01 5QM B 1 I17 A38 E57 C70 E87 Y88 C89 I149 D150 I17 A38 E57 C70 E87 Y88 C89 I149 D150 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4ump C 2.30 BS01 5QM C 1 I17 T19 V25 A38 E57 L61 C70 L86 E87 C89 L139 I149 D150 I17 T19 V22 A35 E51 L55 C64 L80 E81 C83 L133 I143 D144 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4ump D 2.30 BS01 5QM D 1 V25 A38 E57 C70 L86 E87 C89 L139 I149 D150 V24 A37 E56 C69 L85 E86 C88 L138 I148 D149 2.7.11.1,2.7.10.2 Q14680 KDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTISLWQYDHLTATYLLLLAKKARGKPVRLR 4umq A 2.60 BS01 B5S A 1 I17 L27 A38 K40 E57 L61 C70 L86 E87 Y88 C89 P90 E93 L139 I149 D150 I13 L23 A34 K36 E53 L57 C66 L82 E83 Y84 C85 P86 E89 L135 I145 D146 2.7.11.1,2.7.10.2 Q14680 DELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4umr A 3.00 BS01 QBB A 1 I17 V25 L27 A38 K40 C70 E87 Y88 C89 P90 L139 I149 I12 V20 L22 A33 K35 C65 E82 Y83 C84 P85 L134 I144 2.7.11.1,2.7.10.2 Q14680 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4uoe A 2.05 BS01 MTA A 1 Q72 L88 Q93 G124 G125 D127 C146 E147 I148 V152 D178 A179 D196 S197 S198 P203 A204 T206 L207 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 V112 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4uoe A 2.05 BS02 4ZY A 1 V91 Q93 Y102 D196 S197 D199 Q229 Y264 I269 V51 Q53 Y62 D156 S157 D159 Q189 Y224 I229 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4uoe B 2.05 BS01 MTA B 1 Q72 L88 Q93 G124 G125 D127 C146 E147 I148 V152 E177 D178 A179 D196 S197 S198 P203 A204 T206 L207 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 V112 E137 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIE 4uoe B 2.05 BS02 4ZY B 1 I92 Q93 Y102 D196 S197 D199 Q229 Y264 I269 I52 Q53 Y62 D156 S157 D159 Q189 Y224 I229 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIE 4uoe C 2.05 BS01 MTA C 1 Q72 L88 Q93 G124 G125 D127 C146 E147 I148 V152 D178 A179 D196 S197 S198 P203 A204 T206 L207 Q32 L48 Q53 G84 G85 D87 C106 E107 I108 V112 D138 A139 D156 S157 S158 P163 A164 T166 L167 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4uoe C 2.05 BS02 4ZY C 1 V91 I92 Q93 Y102 D196 S197 D199 Y264 I269 V51 I52 Q53 Y62 D156 S157 D159 Y224 I229 2.5.1.16 Q8II73 KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTYDVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYYNYENHSAAFKLPAFLLKEIENI 4urg A 1.90 BS01 C2E A 1 R158 D161 Y176 Y182 L186 R189 R69 D72 Y87 Y93 L97 R100 Q9X2A8 HDPLTGLPNRRYFFELGNRYLDLAKREGKKVFVLFVDLAGFKAINDTYGHLSGDEVLKTVSKRILDRVRRSDVVARYGGDEFTILLYDMKEEYLKSLLERILSTFREPVRVENKHLSVTPNIGVARFPEDGENLEELLKVADMRMYKAKE 4urg A 1.90 BS02 C2E A 2 D155 R156 V157 R158 R159 R189 D66 R67 V68 R69 R70 R100 Q9X2A8 HDPLTGLPNRRYFFELGNRYLDLAKREGKKVFVLFVDLAGFKAINDTYGHLSGDEVLKTVSKRILDRVRRSDVVARYGGDEFTILLYDMKEEYLKSLLERILSTFREPVRVENKHLSVTPNIGVARFPEDGENLEELLKVADMRMYKAKE 4urs A 2.27 BS01 C2E A 1 D155 R156 V157 R158 R159 R189 D69 R70 V71 R72 R73 R103 Q9X2A8 MAYHDPLTGLPNRRYFFELGNRYLDLAKREGKKVFVLFVDLAGFKAINDTYGHLSGDEVLKTVSKRILDRVRRSDVVARYGGDEFTILLYDMKEEYLKSLLERILSTFREPVRVENKHLSVTPNIGVARFPEDGENLEELLKVADMRMYKAKEMKVPYFSLS 4urs A 2.27 BS02 C2E A 2 R158 D161 L175 Y176 D177 M178 K179 Y182 L186 R189 R72 D75 L89 Y90 D91 M92 K93 Y96 L100 R103 Q9X2A8 MAYHDPLTGLPNRRYFFELGNRYLDLAKREGKKVFVLFVDLAGFKAINDTYGHLSGDEVLKTVSKRILDRVRRSDVVARYGGDEFTILLYDMKEEYLKSLLERILSTFREPVRVENKHLSVTPNIGVARFPEDGENLEELLKVADMRMYKAKEMKVPYFSLS 4urs B 2.27 BS01 C2E B 1 R158 D161 L175 Y176 D177 M178 K179 Y182 L186 R189 R72 D75 L89 Y90 D91 M92 K93 Y96 L100 R103 Q9X2A8 MAYHDPLTGLPNRRYFFELGNRYLDLAKREGKKVFVLFVDLAGFKAINDTYGHLSGDEVLKTVSKRILDRVRRSDVVARYGGDEFTILLYDMKEEYLKSLLERILSTFREPVRVENKHLSVTPNIGVARFPEDGENLEELLKVADMRMYKAKEMKVPYFSLS 4urs B 2.27 BS02 C2E B 2 D155 R156 V157 R158 R159 Y182 R189 D69 R70 V71 R72 R73 Y96 R103 Q9X2A8 MAYHDPLTGLPNRRYFFELGNRYLDLAKREGKKVFVLFVDLAGFKAINDTYGHLSGDEVLKTVSKRILDRVRRSDVVARYGGDEFTILLYDMKEEYLKSLLERILSTFREPVRVENKHLSVTPNIGVARFPEDGENLEELLKVADMRMYKAKEMKVPYFSLS 4us8 A 1.49 BS01 FES A 1 Q99 C100 G101 C103 C137 R138 C139 I368 Q99 C100 G101 C103 C137 R138 C139 I368 1.2.99.7 Q46509 25261288 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2.00 BS01 IMD A 1 F47 Y56 Y206 F216 M252 E282 F46 Y55 Y205 F215 M251 E281 2.1.1.44 A0R5M8 25251321 TLSLANYLAADSAAEALRRDVRAGLTAAPKSLPPKWFYDAVGSDLFDQITRLPEYYPTRTEAQILRTRSAEIIAAAGADTLVELGSGTSEKTRMLLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAVCGDFEEHLGKIPHVGRRLVVFLGSTIGNLTPAPRAEFLSTLADTLQPGDSLLLGTDLVKDTGRLVRAYDDAAGVTAAFNRNVLAVVNRELSADFDLDAFEHVAKWNSDEERIEMWLRARTAQHVRVAALDLEVDFAAGEEMLTEVSCKFRPENVVAELAEAGLRQTHWWTDPAGDFGLSLAVRLEHHHH 4uy6 A 2.04 BS01 HIS A 1 F47 Y56 N166 Y206 M252 E282 S284 F46 Y55 N165 Y205 M251 E281 S283 A0R5M8 25251321 TLSLANYLAADSAAEALRRDVRAGLTAAPKSLPPKWFYDAVGSDLFDQITRLPEYYPTRTEAQILRTRSAEIIAAAGADTLVELGSGTSEKTRMLLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAVCGDFEEHLGKIPHVGRRLVVFLGSTIGNLTPAPRAEFLSTLADTLQPGDSLLLGTDLVKDTGRLVRAYDDAAGVTAAFNRNVLAVVNRELSADFDLDAFEHVAKWNSDEERIEMWLRARTAQHVRVAALDLEVDFAAGEEMLTEVSCKFRPENVVAELAEAGLRQTHWWTDPAGDFGLSLAVRL 4uy6 A 2.04 BS02 SAH A 1 Y39 F47 G86 S87 G88 K92 D113 V114 G140 D141 F142 G161 Y38 F46 G85 S86 G87 K91 D112 V113 G139 D140 F141 G160 A0R5M8 25251321 TLSLANYLAADSAAEALRRDVRAGLTAAPKSLPPKWFYDAVGSDLFDQITRLPEYYPTRTEAQILRTRSAEIIAAAGADTLVELGSGTSEKTRMLLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAVCGDFEEHLGKIPHVGRRLVVFLGSTIGNLTPAPRAEFLSTLADTLQPGDSLLLGTDLVKDTGRLVRAYDDAAGVTAAFNRNVLAVVNRELSADFDLDAFEHVAKWNSDEERIEMWLRARTAQHVRVAALDLEVDFAAGEEMLTEVSCKFRPENVVAELAEAGLRQTHWWTDPAGDFGLSLAVRL 4uy7 A 2.31 BS01 HIS A 1 F47 Y56 G161 N166 Y206 M252 E282 S284 F46 Y55 G160 N165 Y205 M251 E281 S283 2.1.1.44 A0R5M8 25251321 TLSLANYLAADSAAEALRRDVRAGLTAAPKSLPPKWFYDAVGSDLFDQITRLPEYYPTRTEAQILRTRSAEIIAAAGADTLVELGSGTSEKTRMLLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAVCGDFEEHLGKIPHVGRRLVVFLGSTIGNLTPAPRAEFLSTLADTLQPGDSLLLGTDLVKDTGRLVRAYDDAAGVTAAFNRNVLAVVNRELSADFDLDAFEHVAKWNSDEERIEMWLRARTAQHVRVAALDLEVDFAAGEEMLTEVSCKFRPENVVAELAEAGLRQTHWWTDPAGDFGLSLAVRLEHHHHH 4uy7 B 2.31 BS01 HIS B 1 Y39 F47 Y56 N166 Y206 M252 E282 S284 Y38 F46 Y55 N165 Y205 M251 E281 S283 2.1.1.44 A0R5M8 25251321 TLSLANYLAADSAAEALRRDVRAGLTAAPKSLPPKWFYDAVGSDLFDQITRLPEYYPTRTEAQILRTRSAEIIAAAGADTLVELGSGTSEKTRMLLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAVCGDFEEHLGKIPHVGRRLVVFLGSTIGNLTPAPRAEFLSTLADTLQPGDSLLLGTDLVKDTGRLVRAYDDAAGVTAAFNRNVLAVVNRELSADFDLDAFEHVAKWNSDEERIEMWLRARTAQHVRVAALDLEVDFAAGEEMLTEVSCKFRPENVVAELAEAGLRQTHWWTDPAGDFGLSLAVRLEHHHH 4uyf A 1.60 BS01 73B A 1 W97 P98 F99 K107 L108 L110 C152 N156 I162 W27 P28 F29 K37 L38 L40 C82 N86 I92 P25440 25249180 NPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVV 4uyf B 1.60 BS01 73B B 1 W97 P98 F99 L108 L110 C152 N156 I162 W22 P23 F24 L33 L35 C77 N81 I87 P25440 25249180 TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQE 4uyf C 1.60 BS01 73B C 1 W97 P98 F99 L108 L110 N156 D161 I162 M165 W23 P24 F25 L34 L36 N82 D87 I88 M91 P25440 25249180 VTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMP 4uyg A 2.50 BS01 73B A 1 W370 P371 V376 L381 L383 C425 N429 H433 D434 V435 M438 W24 P25 V30 L35 L37 C79 N83 H87 D88 V89 M92 P25440 25249180 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 4uyg B 2.50 BS01 73B B 1 W370 P371 F372 V376 L381 L383 C425 N429 H433 V435 M438 W24 P25 F26 V30 L35 L37 C79 N83 H87 V89 M92 P25440 25249180 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 4uyg C 2.50 BS01 73B C 1 W370 P371 F372 V376 L383 C425 N429 H433 V435 M438 W27 P28 F29 V33 L40 C82 N86 H90 V92 M95 P25440 25249180 GKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 4uyg D 2.50 BS01 73B D 1 W370 P371 V376 L381 L383 C425 N429 H433 D434 V435 M438 W23 P24 V29 L34 L36 C78 N82 H86 D87 V88 M91 P25440 25249180 EQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 4uyg E 2.50 BS01 73B E 1 W370 P371 F372 L381 L383 C425 N429 H433 D434 V435 M438 W24 P25 F26 L35 L37 C79 N83 H87 D88 V89 M92 P25440 25249180 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 4uyg F 2.50 BS01 73B F 1 W370 P371 F372 V376 L381 L383 N429 V435 W25 P26 F27 V31 L36 L38 N84 V90 P25440 25249180 LSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPD 4uyh A 1.73 BS01 9S3 A 1 W97 P98 F99 K107 L108 L110 N156 I162 W23 P24 F25 K33 L34 L36 N82 I88 P25440 25249180 VTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQE 4uyh B 1.73 BS01 9S3 B 1 W97 P98 F99 V103 K107 L108 L110 C152 N156 I162 W22 P23 F24 V28 K32 L33 L35 C77 N81 I87 P25440 25249180 TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQ 4v19 0 3.40 BS01 NUC A 1 G37 S38 S39 K40 N41 L42 G43 K45 S46 P47 G48 K49 R50 F51 K54 E57 H59 A63 G64 N65 I66 R71 R74 W75 G84 K85 N86 C88 Y90 Y99 K101 G3 S4 S5 K6 N7 L8 G9 K11 S12 P13 G14 K15 R16 F17 K20 E23 H25 A29 G30 N31 I32 R37 R40 W41 G50 K51 N52 C54 Y56 Y65 K67 F1RT79 TGGSSKNLGGKSPGKRFGIKKMEGHYVHAGNILATQRHFRWHPGAHVGLGKNKCLYALEEGVVRYTKEVYVPNPSNSEAVDLVTRLPQGAVLYKTFVHVVPAKPEGTFKLVAML 4v19 1 3.40 BS01 NUC A 1 K5 G9 N56 R61 P73 L87 G88 H89 Y91 N93 K96 L97 S98 K99 R100 V101 K103 W105 K106 Q108 F110 R112 M129 K4 G8 N55 R60 P72 L86 G87 H88 Y90 N92 K95 L96 S97 K98 R99 V100 K102 W104 K105 Q107 F109 R111 M128 F1RGV8 PLHKVPVGLWKQLRLWEGIYSRLPRHYLRSLEEARTPTPVHYRPHGAKFKINPKNWQRERVEDVPIPVHYPPESQLGLWGGEGWVLGHRYVNNDKLSKRVRKVWKPQLFQRELYSEILDKRFTVTVTMRTLDLIDQACGFDFYILKTPKEDLCSKFGMDLKRGMLLRLARQDPQLHPDDPARRAAIYDRYKAFVIPEAEAEWVGLTLDEAVEKQRLLEEKDPIPLFKIFVEELLGQLQQQALSE 4v19 2 3.40 BS01 NUC A 1 Q119 K122 R125 R166 I174 K182 K184 W186 P187 I188 Y191 L192 N193 K194 K195 N197 R198 K199 R200 F202 M204 R224 L228 R230 K231 K232 K234 Q54 K57 R60 R101 I109 K117 K119 W121 P122 I123 Y126 L127 N128 K129 K130 N132 R133 K134 R135 F137 M139 R159 L163 R165 K166 K167 K169 F1SGC7 LEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEKARPGAWRRDIFGRIIWHKFKQWPIPWYLNKKYNRKRFFAMPYVERFVRMRIEKQARIKARKRSLERKKEKFLQEKFPHL 4v19 3 3.40 BS01 NUC A 1 K35 F36 T37 R38 S39 R40 R71 K73 S74 K76 R77 R78 P79 Y80 K83 K87 M88 K93 A94 H95 K101 S105 K109 K1 F2 T3 R4 S5 R6 R37 K39 S40 K42 R43 R44 P45 Y46 K49 K53 M54 K59 A60 H61 K67 S71 K75 F1STE5 KFTRSRIPDKVFQPSPEDHEKYGGDPQYPHKLHIVTRIKSTKRRPYWEKDIIKMLGLEKAHTPQVHKNIPSVNAKLKVVKHLIRIKPLKLPQGLPTEEDMANTCLKSNGELVVRWLLN 4v19 5 3.40 BS01 NUC A 1 A79 A80 P81 K82 N83 R84 R85 S86 I87 V89 N90 R91 C92 R93 R94 R95 N96 P97 Q98 K99 N106 R131 R138 R139 G142 F149 A1 A2 P3 K4 N5 R6 R7 S8 I9 V11 N12 R13 C14 R15 R16 R17 N18 P19 Q20 K21 N28 R53 R60 R61 G64 F71 I3LTC4 AAPKNRRSIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHILCGYCYEKVRKETAEIRRQMGKQEGGPFRAPTTETVVLYSGETPSEQDQGKRIIERERKRPSWFTQN 4v19 5 3.40 BS02 ZN 5 1 C110 C113 C123 C126 C32 C35 C45 C48 I3LTC4 AAPKNRRSIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHILCGYCYEKVRKETAEIRRQMGKQEGGPFRAPTTETVVLYSGETPSEQDQGKRIIERERKRPSWFTQN 4v19 6 3.40 BS01 NUC A 1 T15 L17 K19 T26 F28 F30 R34 R36 R38 E39 L43 L44 H45 Y46 T3 L5 K7 T14 F16 F18 R22 R24 R26 E27 L31 L32 H33 Y34 SKTILVKMMSQAGTGFSFNTKRSRLREKLTLLHYDPVVKKKVLFVEQK 4v19 7 3.40 BS01 NUC A 1 K50 A51 R52 G53 N54 E55 Y56 Q57 P58 S59 N60 I61 K62 R63 K64 H65 K66 H67 G68 W69 V70 R72 L73 R74 T77 V81 R84 R85 K88 G89 R90 K91 H95 K1 A2 R3 G4 N5 E6 Y7 Q8 P9 S10 N11 I12 K13 R14 K15 H16 K17 H18 G19 W20 V21 R23 L24 R25 T28 V32 R35 R36 K39 G40 R41 K42 H46 W5IDC1 KARGNEYQPSNIKRKHKHGWVRRLRTPTGVQVILRRMHKGRKSLSH 4v19 8 3.40 BS01 NUC A 1 V94 T95 F97 S98 S99 R100 K101 K103 R104 K105 T106 K108 A109 Y112 R113 H118 R124 K126 A127 G128 K131 K132 L133 W134 K135 A138 R140 R142 R143 N151 K152 T153 Q154 K156 K160 T163 F165 W166 R168 R169 D182 V188 V1 T2 F4 S5 S6 R7 K8 K10 R11 K12 T13 K15 A16 Y19 R20 H25 R31 K33 A34 G35 K38 K39 L40 W41 K42 A45 R47 R49 R50 N58 K59 T60 Q61 K63 K67 T70 F72 W73 R75 R76 D89 V95 F1SVC5 VTYFSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTAARKRRLREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQKYQDRTNLKV 4v19 9 3.40 BS01 NUC A 1 F63 K64 T65 K66 G67 V68 L69 K70 K71 R72 R74 L78 V79 K80 R81 R82 G83 W85 F86 Y88 K90 P93 K94 K96 R98 Q99 M100 F1 K2 T3 K4 G5 V6 L7 K8 K9 R10 R12 L16 V17 K18 R19 R20 G21 W23 F24 Y26 K28 P31 K32 K34 R36 Q37 M38 I3LDE8 FKTKGVLKKRCRDCYLVKRRGRWFIYCKTNPKHKQRQM 4v19 9 3.40 BS02 ZN 9 1 C73 C76 C89 H95 C11 C14 C27 H33 I3LDE8 FKTKGVLKKRCRDCYLVKRRGRWFIYCKTNPKHKQRQM 4v19 D 3.40 BS01 NUC A 1 A61 S65 W66 K67 R69 K71 M75 P76 K78 M79 R80 K81 S82 G83 G84 R85 H87 T88 G89 Q90 I91 Q92 V93 H94 I96 G97 G98 H100 K101 Q102 R103 Y104 R105 R131 Y132 P134 R136 S137 L142 K149 W151 R203 Q206 Y207 I208 R209 A210 A211 G212 T213 L229 P230 S231 R233 V251 H253 N254 R256 I258 G259 K260 A261 G262 R263 N264 R265 W266 R270 P271 N272 S273 G274 L275 W276 Q277 R278 K279 G280 G281 W282 A283 G284 R285 K286 R288 K294 Y296 A1 S5 W6 K7 R9 K11 M15 P16 K18 M19 R20 K21 S22 G23 G24 R25 H27 T28 G29 Q30 I31 Q32 V33 H34 I36 G37 G38 H40 K41 Q42 R43 Y44 R45 R71 Y72 P74 R76 S77 L82 K89 W91 R143 Q146 Y147 I148 R149 A150 A151 G152 T153 L169 P170 S171 R173 V191 H193 N194 R196 I198 G199 K200 A201 G202 R203 N204 R205 W206 R210 P211 N212 S213 G214 L215 W216 Q217 R218 K219 G220 G221 W222 A223 G224 R225 K226 R228 K234 Y236 F1RRN2 ATSVSWKSRTKYTVMPVKMRKSGGRNHTGQIQVHGIGGGHKQRYRMIDFLRFRPEHESKPGPFEEKVIAVRYDPCRSADIALVAGGNRKRWIIATENMKAGDTVLNSDHIGRMAVAAREGDAHPLGALPVGTLINNVESEPGRGAQYIRAAGTCGVLLRKVNGTAIIQLPSKRQMQVLETCIATVGRVSNVDHNKRVIGKAGRNRWLGKRPNSGLWQRKGGWAGRKIRPLPPMKSYVKLP 4v19 E 3.40 BS01 NUC A 1 T47 W48 W49 K62 N69 K103 M106 P108 K116 V118 H138 R141 T151 V152 S153 F155 H156 K157 S158 S160 I161 Y165 Q174 V176 K177 I178 N180 T207 T210 I211 G212 K213 G214 F215 Q216 G217 M219 R220 R221 F224 K225 G226 P228 A229 T230 H231 G232 Q233 T234 K235 T236 H237 R238 R239 P240 A242 I243 S244 T245 G246 D247 A249 R250 V251 W252 P253 T255 M257 P258 Q260 L261 G262 N263 I264 D265 R266 F269 L271 S288 P290 G291 H292 K293 N294 K298 K300 L304 P305 T6 W7 W8 K21 N28 K62 M65 P67 K75 V77 H97 R100 T110 V111 S112 F114 H115 K116 S117 S119 I120 Y124 Q133 V135 K136 I137 N139 T166 T169 I170 G171 K172 G173 F174 Q175 G176 M178 R179 R180 F183 K184 G185 P187 A188 T189 H190 G191 Q192 T193 K194 T195 H196 R197 R198 P199 A201 I202 S203 T204 G205 D206 A208 R209 V210 W211 P212 T214 M216 P217 Q219 L220 G221 N222 I223 D224 R225 F228 L230 S247 P249 G250 H251 K252 N253 K257 K259 L263 P264 F1RX24 HGKSVTWWDEHLSEENVPFVKQLVSDENKAQLASKLCPLKDEPWPIHPWEPGSSRVGLIALKLGMMPLWTKDGQKHVVTLLQVQDCHVLKYTPKENHNGRMAALTVGGKTVSHFHKSASILEFYQELGLPPKQKVKIFNVTENAVIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMRRWGFKGQPATHGQTKTHRRPGAISTGDVARVWPGTKMPGQLGNIDRTAFGLKVWRINTKHNIIYVNGSVPGHKNCLVKIKDSKLPAYKDFCKNLPFPTYFPDGDEEALPEDLYDENVCQPGAPSITFT 4v19 F 3.40 BS01 NUC A 1 R92 H97 I101 K104 N105 R108 S110 Y111 T114 K115 R117 A118 V120 R121 G123 R125 K126 V129 Q130 K131 G132 G134 R135 A136 R137 H138 G139 R142 P144 I145 W146 R147 V151 A152 H153 G154 P155 Y161 Y163 M164 P166 M167 K168 V169 R170 H251 K255 T281 P282 L283 Y284 P285 R287 R48 H53 I57 K60 N61 R64 S66 Y67 T70 K71 R73 A74 V76 R77 G79 R81 K82 V85 Q86 K87 G88 G90 R91 A92 R93 H94 G95 R98 P100 I101 W102 R103 V107 A108 H109 G110 P111 Y117 Y119 M120 P122 M123 K124 V125 R126 H207 K211 T237 P238 L239 Y240 P241 R243 F1S3J8 PPVLRKCELPVPAHRRPVQAWIESLRGYEQERVGLTELHPDVFSTAPRLDILHQVAIWQKNFKRISYAKTKTRAEVRGGGRKPWVQKGSGRARHGSIRSPIWRGGGVAHGPRGPTSYYYMLPMKVRVQGLKVALTVKLAQDDLHIVDSLELPTADPQYLIELARYRRWGDSVLLVDLEHEDMPQNVVAATSGLKTFNLVPAVGLNVHSMLKHQTLVLTLPTVAFLEEKLLWHNSRYTPLYPFRLPYCDFP 4v19 I 3.40 BS01 NUC A 1 K61 P63 L64 A65 G66 E67 R69 K70 R72 L73 H74 R75 R76 R78 D85 K87 H88 K91 N121 K9 P11 L12 A13 G14 E15 R17 K18 R20 L21 H22 R23 R24 R26 D33 K35 H36 K39 N69 I3LR45 TVIVERWWKVPLAGEGRKPRLHRRHRVYKLVEDTKHRPKDNLELVLTQSVEELGVRGDLVSVKKSVGRNRLLPQGLAVYASPENKKLFEEEKLLRQEG 4v19 J 3.40 BS01 NUC A 1 G29 S30 K31 V33 T34 R35 R38 H41 K46 A106 L110 R113 I125 P127 N128 V148 H150 N151 G1 S2 K3 V5 T6 R7 R10 H13 K18 A78 L82 R85 I97 P99 N100 V120 H122 N123 F1RWJ0 GSKAVTRHRRVMHFERQKLMAVTEYIPPKPTINPRCLPPPPTPPQEETGLVRLLRREIAAVFRDNRMIAVCQHVALSAEDKLLLRHQLRKHKILMKIFPNQVLKPFLEESKYQNLLPLFVGHNLLLVSEEPKVKEMVRILKGIPFLPLLGGCIDDTILSRQGFINYSK 4v19 K 3.40 BS01 NUC A 1 R21 A22 I38 Q41 R42 P67 T86 V87 S88 K99 G100 A101 R102 H103 T104 K106 K124 A129 F130 Q133 V135 S139 R142 S143 G146 S147 R149 S150 L151 R5 A6 I22 Q25 R26 P51 T70 V71 S72 K83 G84 A85 R86 H87 T88 K90 K108 A113 F114 Q117 V119 S123 R126 S127 G130 S131 R133 S134 L135 F1RU54 SGMIRAIVRAGQARPGPPLGPILGQRGVSINQFCKEFNEKTKDIKEGIPLPTKIFVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARHTGKEVAGLVTLKHVYEIARVKAQDDAFALQDVPLSSVVRSIIGSARSLGIRVVKD 4v19 N 3.40 BS01 NUC A 1 P28 G29 K30 Q49 L50 S68 K71 K75 Y77 S78 H80 P84 G85 F87 R88 Q89 K98 A107 Y109 G110 M111 K114 N115 L116 H117 R118 R119 Y176 R177 P27 G28 K29 Q48 L49 S67 K70 K74 Y76 S77 H79 P83 G84 F86 R87 Q88 K97 A106 Y108 G109 M110 K113 N114 L115 H116 R117 R118 Y175 R176 F1S286 SSFSKAPQQWATFARVWYLLDGKMQPPGKLAAMASVKLQGLHKPVYHQLSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHQKDPVAIVKLAIYGMLPKNLHRRTMMQRLHLFPDEDIPEDILKNLVEELPQPRKVPRRLDEYTQEEIEAFPRVWSPPEDYRL 4v19 O 3.40 BS01 NUC A 1 A31 Q33 K34 M35 T36 R37 H52 R53 R56 I58 H59 Y61 K63 T64 G79 K81 R90 M91 R95 A1 Q3 K4 M5 T6 R7 H22 R23 R26 I28 H29 Y31 K33 T34 G49 K51 R60 M61 R65 F1RQV7 AIQKMTRVRVVDNSALGTTPYHRPPRCIHVYNKTGVGKVGDRILLAIRGQKKKALIVGHRMPGPRMTPRFDSNNVVLLEDNGNPVGTRIKTPIPSSLRQREGEFSKVLAIAQNFV 4v19 P 3.40 BS01 NUC A 1 L24 A25 L27 P29 N30 G32 S33 R34 K35 E37 R38 R39 P40 R41 G42 R43 R44 R45 R47 K48 C49 G50 R51 G52 H53 K54 G55 E56 R57 Q58 R59 T61 R62 P63 R64 F67 E68 G69 G70 Q71 T72 Y75 L76 R77 P79 K80 H87 S88 Q94 R100 R109 T128 Q130 S132 K133 P192 R196 Q198 L16 A17 L19 P21 N22 G24 S25 R26 K27 E29 R30 R31 P32 R33 G34 R35 R36 R37 R39 K40 C41 G42 R43 G44 H45 K46 G47 E48 R49 Q50 R51 T53 R54 P55 R56 F59 E60 G61 G62 Q63 T64 Y67 L68 R69 P71 K72 H79 S80 Q86 R92 R101 T120 Q122 S124 K125 P184 R188 Q190 F1RSH0 GPRALDLLRALPRVSLANLKPNPGSRKPERRPRGRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYLRIPKYGFNEGHSFRHQYQPLSLNRLQYLIDLGRVDPTQPIDLTQLVNGRGVTIQPSKRDYGVQLVEEGADTFKAKVNIEVQMASELAIAAIEKNGGVVTTAFYDPRSLEILCKPVPFFLRGQPIPKRMLPPEALVPYYTDAKNRGYLADPARFPEARLELARKYGYVLPDITKDELFKMLSTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYSS 4v19 P 3.40 BS02 MG P 1 R44 G46 R47 R36 G38 R39 F1RSH0 GPRALDLLRALPRVSLANLKPNPGSRKPERRPRGRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYLRIPKYGFNEGHSFRHQYQPLSLNRLQYLIDLGRVDPTQPIDLTQLVNGRGVTIQPSKRDYGVQLVEEGADTFKAKVNIEVQMASELAIAAIEKNGGVVTTAFYDPRSLEILCKPVPFFLRGQPIPKRMLPPEALVPYYTDAKNRGYLADPARFPEARLELARKYGYVLPDITKDELFKMLSTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYSS 4v19 Q 3.40 BS01 NUC A 1 K31 R63 R64 R66 K67 N68 L69 R73 G100 H101 E103 M104 R111 R133 K134 M136 G137 Q138 R139 M140 G141 G142 G143 K144 G145 H181 K182 L183 P184 R227 K228 V229 S231 P232 Y233 K244 K1 R33 R34 R36 K37 N38 L39 R43 G70 H71 E73 M74 R81 R103 K104 M106 G107 Q108 R109 M110 G111 G112 G113 K114 G115 H151 K152 L153 P154 R197 K198 V199 S201 P202 Y203 K214 F1RI89 KTLLPVPTFEDVAIPEKPKLRFVERVPLVPKVRRERKNLSDIRGPSTEATEFTEGRFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFALWRVPAPFKPITRKGMGQRMGGGKGAIDHYVTPVKAGRLIVEMGGRCEFKEVQGFLDLVAHKLPFPAKAVSRETLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGRYWGKFYTPERV 4v19 Q 3.40 BS02 MG Q 1 H181 L183 F185 H151 L153 F155 F1RI89 KTLLPVPTFEDVAIPEKPKLRFVERVPLVPKVRRERKNLSDIRGPSTEATEFTEGRFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFALWRVPAPFKPITRKGMGQRMGGGKGAIDHYVTPVKAGRLIVEMGGRCEFKEVQGFLDLVAHKLPFPAKAVSRETLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGRYWGKFYTPERV 4v19 R 3.40 BS01 NUC A 1 I9 S10 H11 G12 R13 V14 F15 R16 R17 G19 L20 G21 P22 H27 Q30 N31 L32 H39 I42 E43 S45 W46 A47 R48 T81 E82 Q116 D117 A119 K120 I1 S2 H3 G4 R5 V6 F7 R8 R9 G11 L12 G13 P14 H19 Q22 N23 L24 H31 I34 E35 S37 W38 A39 R40 T73 E74 Q108 D109 A111 K112 F1RMQ4 ISHGRVFRRLGLGPESRIHLLQNLLTGLVRHERIEASWARVDELRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRFQGQNGGYTRMLQIPNRNEQDRAKMAVIEYKGNCLPPLPLPRRDSNLTLLNQLLQGLRQDQEASS 4v19 R 3.40 BS02 MG R 1 S10 R13 S2 R5 F1RMQ4 ISHGRVFRRLGLGPESRIHLLQNLLTGLVRHERIEASWARVDELRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRFQGQNGGYTRMLQIPNRNEQDRAKMAVIEYKGNCLPPLPLPRRDSNLTLLNQLLQGLRQDQEASS 4v19 S 3.40 BS01 NUC A 1 R66 R176 E180 R29 R139 E143 F1SB64 PVENEAVAPEFTNRNPRNLELLAVARKERGWGTVWPSREFWHRLRVIRTQHHIEALVEHRNGQVVVSASTREWAIKKHLYSTRNVVACESVGRVLAERCLEAGINFMVYHPTPWEAASDSIKRLQHAMTEGGVVLREPRRIYE 4v19 T 3.40 BS01 NUC A 1 R84 G85 R86 K91 S141 G142 G146 T148 P228 W229 K231 R232 R235 K237 W260 L265 R271 R16 G17 R18 K23 S73 G74 G78 T80 P160 W161 K163 R164 R167 K169 W192 L197 R203 I3LNJ0 QRPETRFLSPEFIPPRGRTNPLKFQIERKDMLERRKILHIPEFYVGSILRVTTADPYASAKTSQFLGICIQRSGSGLGATFILRNTIEGQGVEICFELYNPRIQEIQVVKLEKRLDNSLLYLRDALPEYSTFDVNMKPITQEFNQEVPVNQLKVKMKPKPWSKRWERPKFNIKGIRFDLCLTEEQMREAQKWSQPWLEFDMMREYDTSKIEAAIWDEIEASKNS 4v19 U 3.40 BS01 NUC A 1 L10 R11 S12 R13 V14 T15 D16 R17 Y18 R20 H30 F31 R32 R34 K35 R37 C38 Y39 R40 V43 R44 R48 A49 K52 C53 R55 A56 R57 R58 L59 K60 K61 R62 L64 R65 W68 I69 K82 Y83 P84 I88 N98 R99 R124 F128 L1 R2 S3 R4 V5 T6 D7 R8 Y9 R11 H21 F22 R23 R25 K26 R28 C29 Y30 R31 V34 R35 R39 A40 K43 C44 R46 A47 R48 R49 L50 K51 K52 R53 L55 R56 W59 I60 K73 Y74 P75 I79 N89 R90 R115 F119 F1RJD0 LRSRVTDRYWRVQEVLKHARHFRGRKNRCYRLAVRAVTRAFVKCTRARRLKKRSLRTLWINRITAASQEHGLKYPAFIINLIKCQVELNRKVLADLAIYEPKTFKSLAALAKRRREEGFAAALGDGKEPDGIFSRVVQHR 4v19 V 3.40 BS01 NUC A 1 L60 P64 W65 A106 G107 H108 N122 K173 N175 K177 K180 R181 K182 Y184 R186 K187 R188 T190 V191 N192 L6 P10 W11 A52 G53 H54 N68 K119 N121 K123 K126 R127 K128 Y130 R132 K133 R134 T136 V137 N138 F1RY70 VPKTSLGSPPWPDIVLPDPVEETRHHAEVVGQVNELIAAGRYGRLFAVVHFAGHQWKVTAEDLILIENELDVACGERIRLEKVLLVGADNFTLLGKPLLGKELVRVEATVIEKTESWPKINMKFQKRKNYQRKRITVNPQTVLRINSIEIAPCLC 4v19 W 3.40 BS01 NUC A 1 I45 S46 R47 K48 W49 K52 R76 K79 Y80 S81 K84 W86 R93 D108 K109 K110 T144 G146 R147 Q149 K152 R153 R155 Y156 H157 G158 R159 G160 R161 F162 G163 I164 M165 E166 K167 V168 F169 H171 F173 N203 R204 T205 T207 H208 I1 S2 R3 K4 W5 K8 R32 K35 Y36 S37 K40 W42 R49 D64 K65 K66 T100 G102 R103 Q105 K108 R109 R111 Y112 H113 G114 R115 G116 R117 F118 G119 I120 M121 E122 K123 V124 F125 H127 F129 N159 R160 T161 T163 H164 ISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFSDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLYVAESTSGRGQYLKRIRYHGRGRFGIMEKVFCHYFVKLVEGPPPPREAPKTAVAHAREYIQELRNRTITHAL 4v19 X 3.40 BS01 NUC A 1 N4 L6 L9 G32 Q35 R43 T49 R50 V51 R54 R69 T70 R71 V72 Q73 Y74 S76 N77 R78 R80 R83 N84 K93 Y96 N3 L5 L8 G31 Q34 R42 T48 R49 V50 R53 R68 T69 R70 V71 Q72 Y73 S75 N76 R77 R79 R82 N83 K92 Y95 ARNVLYPLYQLGNPQLRVFRTNFFIQLVRPGTAQPEDTVQFRIPMEMTRVDLRNYLERIYNVPVAAVRTRVQYGSNRRRDHRNIRIKKPDYKVAYVQLALGQTFTFPDLFPERKGRQKHSPDPRRGGVPGWFGL 4v19 Y 3.40 BS01 NUC A 1 N18 R20 G22 M23 S24 K34 R40 R41 R42 R43 R83 W85 H94 Y95 R96 S111 P114 N6 R8 G10 M11 S12 K22 R28 R29 R30 R31 R71 W73 H82 Y83 R84 S99 P102 F1RHJ1 VTLPPNYRYGMSRPGSLSDKRKNPPGTRRRRVPVEPISDEDWHLFCGDKVEILEGKDAGKQGKVVQVIRQRNWVVVEGLNTHYRYVGKTVDYRGTMIPSEAPLLHNQVKLVDPTDRKPTDVEWRFTEAGERVRVSTRSGRIIPKPEFPRADGIVPETWIDGPKDTSVEDALEKTYVPRLKTLEEEVMEAMGIQETRRHKKVYWY 4v1a k 3.40 BS01 III z 1 T131 M132 E133 L135 T74 M75 E76 L78 F1SUS9 YRSKPTHGIGRYKHLVKAQVRPINLGTDYEYGVLNIHLIAYDMALAESYAQYVHNLCNHLAIKVEESYAMPTKTMEVLQLQMFLDAVLTTHERVVQISGLSATFAEIFLEIIHSNLPEGVKLSVREHTEED 4v1a k 3.40 BS02 UNK z 1 L135 L137 L78 L80 F1SUS9 YRSKPTHGIGRYKHLVKAQVRPINLGTDYEYGVLNIHLIAYDMALAESYAQYVHNLCNHLAIKVEESYAMPTKTMEVLQLQMFLDAVLTTHERVVQISGLSATFAEIFLEIIHSNLPEGVKLSVREHTEED 4v1a x 3.40 BS01 ZN x 1 C70 C73 C108 C36 C39 C74 F1RRH6 FREVVEILDGKTTIIEGRITETPQESPNPPNPTGQCPICRWNLKHKYNYEDVLLLSQFIRPHGGMLPRRITGLCQEEHLKIEECVKMAHRAGLLPNHRPKLPEGFVPKSKPRLNRYLTRWSPRSVKPIYNKGHRWNKVRMPVGSPLLKDNVSYSGRPLLLYH 4w4z A 2.41 BS01 III E 1 I59 Q71 C73 M76 T104 R106 L111 P112 R162 M164 C191 I192 A193 I32 Q44 C46 M49 T77 R79 L84 P85 R135 M137 C164 I165 A166 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w4z B 2.41 BS01 III F 1 I59 Q71 C73 V75 T104 R106 L111 P112 R162 M164 L166 C191 I32 Q44 C46 V48 T77 R79 L84 P85 R135 M137 L139 C164 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w4z C 2.41 BS01 III G 1 I59 Q71 C73 V75 M76 T104 L105 R106 L111 P112 R162 M164 L166 C191 A193 I32 Q42 C44 V46 M47 T75 L76 R77 L82 P83 R133 M135 L137 C162 A164 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w4z D 2.41 BS01 III H 1 I59 Q71 C73 N74 M76 E77 T104 R106 L111 P112 R162 M164 L166 C191 I192 A193 I32 Q41 C43 N44 M46 E47 T74 R76 L81 P82 R132 M134 L136 C161 I162 A163 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w50 A 2.42 BS01 III E 1 V57 I59 Q71 C73 V75 M76 T104 R106 L111 P112 M115 R162 M164 C191 A193 V30 I32 Q44 C46 V48 M49 T77 R79 L84 P85 M88 R135 M137 C164 A166 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKA 4w50 A 2.42 BS02 BU2 A 1 E30 I170 K202 E3 I143 K175 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKA 4w50 B 2.42 BS01 III F 1 V57 I59 Q71 C73 M76 T104 R106 L111 P112 I159 M164 C191 V30 I32 Q44 C46 M49 T77 R79 L84 P85 I132 M137 C164 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKA 4w50 B 2.42 BS02 BU2 B 1 I170 D172 I143 D145 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKA 4w50 C 2.42 BS01 III G 1 I59 Q71 C73 M76 T104 L105 R106 L111 P112 M164 L166 C191 I32 Q44 C46 M49 T77 L78 R79 L84 P85 M137 L139 C164 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w50 C 2.42 BS02 BU2 C 1 D151 S153 E169 D124 S126 E142 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w50 D 2.42 BS01 III H 1 I59 Q71 C73 N74 T104 R106 L111 P112 I159 R162 M164 C191 I32 Q44 C46 N47 T77 R79 L84 P85 I132 R135 M137 C164 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w50 D 2.42 BS02 BU2 D 1 E30 E100 R198 E3 E73 R171 2.7.10.1 P54764 25268696 GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 4w78 E 1.54 BS01 CA E 1 D95 K166 D90 K161 W6I895 25203216 DIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVWQVGDEDVAEMNWRILKFKPA 4w78 G 1.54 BS01 CA G 1 D85 L87 D79 L81 W6I895 25203216 IQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVWQVGDEDVAEMNWRILKFKP 4w7b E 1.76 BS01 CA E 1 D95 K166 D90 K161 W6I895 25203216 DIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVWQVGDEDVAEMNWRILKFKPA 4w7b G 1.76 BS01 CA G 1 D85 L87 D79 L81 W6I895 25203216 IQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVWQVGDEDVAEMNWRILKFKP 4wcu A 2.35 BS01 3KQ A 1 H160 T271 M273 D318 L319 N321 T333 I336 M337 F340 M357 Q369 F372 F432 Q433 L436 H71 T182 M184 D229 L230 N232 T244 I247 M248 F251 M268 Q280 F283 F326 Q327 L330 3.1.4.53 Q08499 24984230 DVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPTEKFQFEL 4wcu A 2.35 BS02 ZN A 1 H164 H200 D201 D318 H75 H111 D112 D229 3.1.4.53 Q08499 24984230 DVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPTEKFQFEL 4wcu B 2.35 BS01 3KQ B 1 H160 T271 M273 D318 L319 N321 Y329 T333 I336 F340 M357 Q369 F372 I376 F432 Q433 H76 T187 M189 D231 L232 N234 Y242 T246 I249 F253 M270 Q282 F285 I289 F329 Q330 3.1.4.53 Q08499 24984230 KTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIGQTEKFQFEL 4wcu B 2.35 BS02 ZN B 1 H164 H200 D201 D318 H80 H116 D117 D231 3.1.4.53 Q08499 24984230 KTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIGQTEKFQFEL 4wcu C 2.35 BS01 3KQ C 1 T271 M273 D318 L319 N321 I336 F340 Q369 F372 F432 Q433 T181 M183 D222 L223 N225 I240 F244 Q273 F276 F319 Q320 3.1.4.53 Q08499 24984230 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPTEKFQFE 4wcu C 2.35 BS02 ZN C 1 H164 H200 D201 D318 H74 H110 D111 D222 3.1.4.53 Q08499 24984230 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPTEKFQFE 4wcu D 2.35 BS01 3KQ D 1 Y159 T271 M273 D318 L319 T333 I336 F340 M357 Q369 F372 I376 F432 Q433 L436 Y70 T182 M184 D229 L230 T244 I247 F251 M268 Q280 F283 I287 F326 Q327 L330 3.1.4.53 Q08499 24984230 DVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPTEKFQFEL 4wcu D 2.35 BS02 ZN D 1 H164 H200 D201 D318 H75 H111 D112 D229 3.1.4.53 Q08499 24984230 DVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPTEKFQFEL 4wec A 1.55 BS01 NAD A 1 G16 A18 S19 G20 I21 D40 I41 V60 D61 V62 N88 G90 T140 A141 S142 Y156 K160 P186 G187 P188 V189 G17 A19 S20 G21 I22 D41 I42 V61 D62 V63 N89 G91 T141 A142 S143 Y157 K161 P187 G188 P189 V190 A0QVJ7 SMDLTQRLAGKVAVITGGASGIGLATGRRLRAEGATVVVGDIDPTTGKAAADELEGLFVPVDVSEQEAVDNLFDTAASTFGRVDIAFNNAGISPPEDDLIENTDLPAWQRVQDINLKSVYLSCRAALRHMVPAGKGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNALCPGPVNTPLLQELFAKDPERAARRLVHIPLGRFAEPEELAAAVAFLASDDASFITGSTFLVDGGISSAYVTPL 4wec B 1.55 BS01 NAD B 1 G16 S19 G20 I21 D40 I41 V60 D61 V62 N88 G90 I113 T140 A141 S142 Y156 K160 P186 G187 P188 V189 G13 S16 G17 I18 D37 I38 V57 D58 V59 N85 G87 I110 T137 A138 S139 Y153 K157 P183 G184 P185 V186 A0QVJ7 TQRLAGKVAVITGGASGIGLATGRRLRAEGATVVVGDIDPTTGKAAADELEGLFVPVDVSEQEAVDNLFDTAASTFGRVDIAFNNAGISPPEDDLIENTDLPAWQRVQDINLKSVYLSCRAALRHMVPAGKGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNALCPGPVNTPLLQELFAKDPERAARRLVHIPLGRFAEPEELAAAVAFLASDDASFITGSTFLVDGGISSAYVTPL 4wec C 1.55 BS01 NAD C 1 G16 S19 G20 I21 D40 I41 V60 D61 V62 N88 G90 I113 T140 A141 S142 Y156 K160 P186 G187 P188 V189 G12 S15 G16 I17 D36 I37 V56 D57 V58 N84 G86 I109 T136 A137 S138 Y152 K156 P182 G183 P184 V185 A0QVJ7 QRLAGKVAVITGGASGIGLATGRRLRAEGATVVVGDIDPTTGKAAADELEGLFVPVDVSEQEAVDNLFDTAASTFGRVDIAFNNAGISPPEDDLIENTDLPAWQRVQDINLKSVYLSCRAALRHMVPAGKGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNALCPGPVNTPLLQELFAKDPERAARRLVHIPLGRFAEPEELAAAVAFLASDDASFITGSTFLVDGGISSAYVTPL 4wec D 1.55 BS01 NAD D 1 G16 S19 G20 I21 D40 I41 V60 D61 V62 N88 G90 T140 A141 S142 Y156 K160 P186 G187 P188 V189 G17 S20 G21 I22 D41 I42 V61 D62 V63 N89 G91 T141 A142 S143 Y157 K161 P187 G188 P189 V190 A0QVJ7 SMDLTQRLAGKVAVITGGASGIGLATGRRLRAEGATVVVGDIDPTTGKAAADELEGLFVPVDVSEQEAVDNLFDTAASTFGRVDIAFNNAGISPPEDDLIENTDLPAWQRVQDINLKSVYLSCRAALRHMVPAGKGSIINTASFVAVMGSATSQISYTASKGGVLAMSRELGVQYARQGIRVNALCPGPVNTPLLQELFAKDPERAARRLVHIPLGRFAEPEELAAAVAFLASDDASFITGSTFLVDGGISSAYVTPL 4wf8 A 1.70 BS01 ZN A 1 C1097 C1099 C1145 H1149 C109 C111 C157 H161 X2G809 25243902 KGSVVIVGRINLSGDTAYAQQTRGAAACQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVSTRGVAKAVDFIPVESLETTMR 4wf8 A 1.70 BS02 2R9 A 1 Q1041 T1042 F1043 Y1056 H1057 G1058 V1078 D1079 D1081 R1123 I1132 L1135 K1136 G1137 S1139 F1154 R1155 A1156 A1157 V1158 D1168 Q53 T54 F55 Y68 H69 G70 V90 D91 D93 R135 I144 L147 K148 G149 S151 F166 R167 A168 A169 V170 D180 X2G809 25243902 KGSVVIVGRINLSGDTAYAQQTRGAAACQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVSTRGVAKAVDFIPVESLETTMR 4wh6 A 1.99 BS01 ZN A 1 C1097 C1099 C1145 H1149 C117 C119 C165 H169 A8DG50 25243902 SHMASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFKAAVSTRGVAKAVDFIPVESLETTMR 4wh6 A 1.99 BS02 2R9 A 1 Q1041 T1042 F1043 H1057 G1058 V1078 D1081 R1123 I1132 L1135 K1136 G1137 S1138 S1139 F1154 K1155 A1156 A1157 V1158 D1168 Q61 T62 F63 H77 G78 V98 D101 R143 I152 L155 K156 G157 S158 S159 F174 K175 A176 A177 V178 D188 A8DG50 25243902 SHMASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFKAAVSTRGVAKAVDFIPVESLETTMR 4whx A 2.05 BS01 ALA A 1 Y98 R100 K161 G198 T258 A259 Y97 R99 K160 G197 T257 A258 2.6.1.42 B7CIR9 SMADRDGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNSAKIFQMDVPFDQETLEAAQRDVVRENKLESCYLRPIIWIGSEKLGVSAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNRGKLYTPDLASCLDGITRDTVITLAKEAGIEVIEKRITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGGGARGPITEKLQSAFFDVVNGKSAKHADWLTKI 4whx C 2.05 BS01 ALA C 1 G40 Y98 K161 G198 T258 A259 G39 Y97 K160 G197 T257 A258 2.6.1.42 B7CIR9 SMADRDGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNSAKIFQMDVPFDQETLEAAQRDVVRENKLESCYLRPIIWIGSEKLGVSAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNRGKLYTPDLASCLDGITRDTVITLAKEAGIEVIEKRITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGGGARGPITEKLQSAFFDVVNGKSAKHADWLTKI 4whx D 2.05 BS01 ALA D 1 F38 Y98 R100 K161 T258 A259 F37 Y97 R99 K160 T257 A258 2.6.1.42 B7CIR9 SMADRDGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNSAKIFQMDVPFDQETLEAAQRDVVRENKLESCYLRPIIWIGSEKLGVSAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNRGKLYTPDLASCLDGITRDTVITLAKEAGIEVIEKRITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGGGARGPITEKLQSAFFDVVNGKSAKHADWLTKI 4whx E 2.05 BS01 ALA E 1 G40 Y98 R100 K161 G198 A259 G39 Y97 R99 K160 G197 A258 2.6.1.42 B7CIR9 SMADRDGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNSAKIFQMDVPFDQETLEAAQRDVVRENKLESCYLRPIIWIGSEKLGVSAKGNTIHVAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADGYDEALLLDVDGYVSEGSGENFFLVNRGKLYTPDLASCLDGITRDTVITLAKEAGIEVIEKRITRDEVYTADEAFFTGTAAEVTPIRELDNRTIGGGARGPITEKLQSAFFDVVNGKSAKHADWLTKI 4wiw A 2.64 BS01 CA A 1 Y465 G466 D467 D470 D473 Y125 G126 D127 D130 D133 B8FWJ2 NAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wiw A 2.64 BS02 CA A 2 N586 N588 N246 N248 B8FWJ2 NAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wiw B 2.64 BS01 CA B 1 Y465 G466 D467 D470 D473 Y125 G126 D127 D130 D133 B8FWJ2 NAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wiw C 2.64 BS01 CA C 1 Y465 D467 D470 P471 D473 D513 Y125 D127 D130 P131 D133 D173 B8FWJ2 NAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wiw D 2.64 BS01 CA D 1 Y465 G466 D467 D470 D473 Y126 G127 D128 D131 D134 B8FWJ2 SNAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wiw E 2.64 BS01 CA E 1 Y465 D467 D470 P471 D473 D513 Y125 D127 D130 P131 D133 D173 B8FWJ2 NAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wiw F 2.64 BS01 CA F 1 Y465 D467 D470 D473 Y125 D127 D130 D133 B8FWJ2 NAKISLQYWDGYASYETYLRQLSLIPGKATDYVDYVSPNWRGSIGTDGSLKLVWDEGSSNYKQLTNMAHGLGMKVLPLINGSGATLNTLLKSPAAREKLIGEIVVLLKNTNADGVVIDFETPLDYGDVKDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMSSSQYWLDAYDYEALSHAVDYLHVMTYDHHYRTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDANGNPTYNSTAFGYSKALELADSYGATITYSKYNDADPVGTPTFKYTDEKGVEHTVFFDDYTSWNAKLSIINEFGLAGVGPWAMGWVDENTAEGLFPLLNQHLR 4wjb A 1.95 BS01 ZN A 1 H88 D99 H195 H81 D92 H188 3.5.1.87 B4EHA1 MPRVDGDRLWASLERMAQIGATPKGGVCRLALTDLDRESRDLFVQWAREAGCTVRVDRMGNVFARRAGRRPDAAPVMTGSHADSQPTGGRYDGIYGVLGGLEVVRALNDAAIETERPVDVVIWTNEEGSRFAPAMVSAGVFSGVYTLEYGLSRTDGAGRTIGEELERIGYAGAEPVGGYPVHAAYELHIEQGAILERAGKTIGVVTAGQGQRWYEVTLTGVDAHAGTTPMAFRRDALVGAARMISFVEVLGRRYAPDARATVGMIEARPNSRNTVPGGCFFTVEFRHPDDAVLDELDAALRAELARVADETGLGAQIEQIFTYAPVPFAPRCIDTVRDAARSLGLSHMDIVSGAGHDACYVARVAPTGMIFVPCVDGLSHNEAEAITPEWATAGADVLLRAVLQSAQEA 4wjb B 1.95 BS01 ZN B 1 H88 D99 E134 H195 H387 H81 D92 E127 H188 H378 3.5.1.87 B4EHA1 MPRVDGDRLWASLERMAQIGATPKGGVCRLALTDLDRESRDLFVQWAREAGCTVRVDRMGNVFARRAGRRPDAAPVMTGSHADSQPTGGRYDGIYGVLGGLEVVRALNDAAIETERPVDVVIWTNEEGSRFAPAMVSAGVFSGVYTLEYGLSRTDGAGRTIGEELERIGYAGAEPVGGYPVHAAYELHIEQGAILERAGKTIGVVTAGQGQRWYEVTLTGVDAHAGTTPMAFRRDALVGAARMISFVEVLGRRYAPDARATVGMIEARPNSRNTVPGGCFFTVEFRHPDDAVLDELDAALRAELARVADETGLGAQIEQIFTYAPVPFAPRCIDTVRDAARSLGLSHMDIVSGAGHDACYVARVAPTGMIFVPCVLSHNEAEAITPEWATAGADVLLRAVLQSAQEA 4wjb C 1.95 BS01 ZN C 1 H88 D99 E134 H195 H387 H81 D92 E127 H188 H378 3.5.1.87 B4EHA1 MPRVDGDRLWASLERMAQIGATPKGGVCRLALTDLDRESRDLFVQWAREAGCTVRVDRMGNVFARRAGRRPDAAPVMTGSHADSQPTGGRYDGIYGVLGGLEVVRALNDAAIETERPVDVVIWTNEEGSRFAPAMVSAGVFSGVYTLEYGLSRTDGAGRTIGEELERIGYAGAEPVGGYPVHAAYELHIEQGAILERAGKTIGVVTAGQGQRWYEVTLTGVDAHAGTTPMAFRRDALVGAARMISFVEVLGRRYAPDARATVGMIEARPNSRNTVPGGCFFTVEFRHPDDAVLDELDAALRAELARVADETGLGAQIEQIFTYAPVPFAPRCIDTVRDAARSLGLSHMDIVSGAGHDACYVARVAPTGMIFVPCVLSHNEAEAITPEWATAGADVLLRAVLQSAQEA 4wjb D 1.95 BS01 ZN D 1 H88 D99 E134 H195 Q198 H81 D92 E127 H188 Q191 3.5.1.87 B4EHA1 MPRVDGDRLWASLERMAQIGATPKGGVCRLALTDLDRESRDLFVQWAREAGCTVRVDRMGNVFARRAGRRPDAAPVMTGSHADSQPTGGRYDGIYGVLGGLEVVRALNDAAIETERPVDVVIWTNEEGSRFAPAMVSAGVFSGVYTLEYGLSRTDGAGRTIGEELERIGYAGAEPVGGYPVHAAYELHIEQGAILERAGKTIGVVTAGQGQRWYEVTLTGVDAHAGTTPMAFRRDALVGAARMISFVEVLGRRYAPDARATVGMIEARPNSRNTVPGGCFFTVEFRHPDDAVLDELDAALRAELARVADETGLGAQIEQIFTYAPPFAPRCIDTVRDAARSLGLSHMDIVSGAGHDACYVARVAPTGMIFVPCVSHNEAEAITPEWATAGADVLLRAVLQSAQEA