2mmh A BS01 ZN A 1 C14 C23 C26 C14 C23 C26 P12296 GSTAMATTMEQEICAHSMTFEECPKCSALQYRNGFYLLKYDEEWYPEELLTDGEDDVFDPDLDMEVVFETQ 2mml A BS01 ZN A 1 C14 A15 C23 C14 A15 C23 P12296 GSTAMATTMEQEICAHSMTFEECPKCSALQYRNGFYLLKYDEEWYPEELLTDGEDDVFDPDLDMEVVFETQ 2mte A BS01 CA A 1 D7 N9 D11 K13 V14 N15 D18 D7 N9 D11 K13 V14 N15 D18 3.2.1.176 P0C2S5 25270376 STKLYGDVNDDGKVNSTDAVALKRYVLRSGISINTDNADLNEDGRVNSTDLGILKRYILKEIDTLPYKN 2mte A BS02 CA A 2 D39 N41 D43 R45 D50 D39 N41 D43 R45 D50 3.2.1.176 P0C2S5 25270376 STKLYGDVNDDGKVNSTDAVALKRYVLRSGISINTDNADLNEDGRVNSTDLGILKRYILKEIDTLPYKN 2ruk B BS01 III A 1 Q17 K18 K19 K51 C52 Q53 K54 I55 S56 P57 K60 K62 Q64 L65 Q66 N76 K93 Q97 K104 R105 K106 A107 N108 Q17 K18 K19 K51 C52 Q53 K54 I55 S56 P57 K60 K62 Q64 L65 Q66 N76 K93 Q97 K104 R105 K106 A107 N108 P32780 25216154 MATSSEEVLLIVKKVRQKKQDGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSNESTAVKERDAVKDLLQQLLPKFKRKAN 3j7y D 3.40 BS01 NUC A 1 A61 F63 W66 K67 R69 I74 T75 P76 R80 K81 S82 G84 R85 D86 H87 T88 G89 R90 I91 R92 V93 I96 G97 G98 H100 K101 Q102 R103 Y104 R105 I127 Q128 R130 Y131 P133 R135 L141 R202 Q205 Y206 I207 R208 A209 A210 G211 T212 L228 P229 S230 M234 R246 H252 N253 I257 G258 K259 A260 G261 R262 N263 R264 W265 L266 R269 P270 N271 G273 R274 W275 H276 R277 K278 G279 G280 W281 A282 G283 R284 K285 I286 R287 K293 Y295 A1 F3 W6 K7 R9 I14 T15 P16 R20 K21 S22 G24 R25 D26 H27 T28 G29 R30 I31 R32 V33 I36 G37 G38 H40 K41 Q42 R43 Y44 R45 I67 Q68 R70 Y71 P73 R75 L81 R142 Q145 Y146 I147 R148 A149 A150 G151 T152 L168 P169 S170 M174 R186 H192 N193 I197 G198 K199 A200 G201 R202 N203 R204 W205 L206 R209 P210 N211 G213 R214 W215 H216 R217 K218 G219 G220 W221 A222 G223 R224 K225 I226 R227 K233 Y235 Q5T653 25278503 ANFVSWKSRTKYTITPVKMRKSGGRDHTGRIRVHGIGGGHKQRYRMIDFLRFRPEETKSGPFEEKVIQVRYDPCRSADIALVAGGSRKRWIIATENMQAGDTILNSNHIGRMAVAAREGDAHPLGALPVGTLINNVESEPGRGAQYIRAAGTCGVLLRKVNGTAIIQLPSKRQMQVLETCVATVGRVSNVDHNKRVIGKAGRNRWLGKRPNSGRWHRKGGWAGRKIRPLPPMKSYV 3j7y E 3.40 BS01 NUC A 1 W48 W49 K62 V65 D69 K103 M106 M107 P108 K116 V118 V152 S153 R154 R156 K157 I161 Y165 Q174 V176 I178 N180 T210 I211 G212 K213 G214 F215 G217 M219 K220 R221 F224 K225 G226 Q227 P228 A229 T230 H231 G232 Q233 T234 K235 T236 H237 R238 R239 P240 G241 A242 V243 A244 T245 G246 D247 I248 G249 R250 V251 W252 P253 G254 T255 M257 P258 K260 G262 N263 I264 Y265 R266 T267 E268 Y269 L271 G287 S288 V289 P290 G291 H292 K293 N294 K298 K300 K303 L304 P305 W4 W5 K18 V21 D25 K59 M62 M63 P64 K72 V74 V104 S105 R106 R108 K109 I113 Y117 Q126 V128 I130 N132 T162 I163 G164 K165 G166 F167 G169 M171 K172 R173 F176 K177 G178 Q179 P180 A181 T182 H183 G184 Q185 T186 K187 T188 H189 R190 R191 P192 G193 A194 V195 A196 T197 G198 D199 I200 G201 R202 V203 W204 P205 G206 T207 M209 P210 K212 G214 N215 I216 Y217 R218 T219 E220 Y221 L223 G239 S240 V241 P242 G243 H244 K245 N246 K250 K252 K255 L256 P257 P09001 25278503 SGTWWDEHLSEENVPFIKQLVSDEDKAQLASKLCPLKDEPWPIHPWEPGSFRVGLIALKLGMMPLWTKDGQKHVVTLLQVQDCHVLKYTSKGKMATLSVGGKTVSRFRKATSILEFYRELGLPPKQTVKIFNITDNAAIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPATHGQTKTHRRPGAVATGDIGRVWPGTKMPGKMGNIYRTEYGLKVWRINTKHNIIYVNGSVPGHKNCLVKVKDSKLPAYKDLGKNLPFPTYFPDGDEEELPEDLYDENVCQPGAPSITFA 3j7y E 3.40 BS02 MG E 1 T234 H237 T186 H189 P09001 25278503 SGTWWDEHLSEENVPFIKQLVSDEDKAQLASKLCPLKDEPWPIHPWEPGSFRVGLIALKLGMMPLWTKDGQKHVVTLLQVQDCHVLKYTSKGKMATLSVGGKTVSRFRKATSILEFYRELGLPPKQTVKIFNITDNAAIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPATHGQTKTHRRPGAVATGDIGRVWPGTKMPGKMGNIYRTEYGLKVWRINTKHNIIYVNGSVPGHKNCLVKVKDSKLPAYKDLGKNLPFPTYFPDGDEEELPEDLYDENVCQPGAPSITFA 3j7y F 3.40 BS01 NUC A 1 R92 H97 M101 K104 N105 R108 Y111 A112 K113 T114 T116 R117 A118 V120 R121 G123 R125 K126 Q130 K131 T133 G134 R135 A136 R137 H138 G139 R142 S143 P144 L145 W146 R147 G148 V151 A152 H153 G154 P155 P158 Y161 Y163 M164 L165 P166 M167 K168 V169 R170 L172 K255 R281 P282 P285 R48 H53 M57 K60 N61 R64 Y67 A68 K69 T70 T72 R73 A74 V76 R77 G79 R81 K82 Q86 K87 T89 G90 R91 A92 R93 H94 G95 R98 S99 P100 L101 W102 R103 G104 V107 A108 H109 G110 P111 P114 Y117 Y119 M120 L121 P122 M123 K124 V125 R126 L128 K211 R237 P238 P241 Q9BYD3 25278503 EPVLRKVELPVPTHRRPVQAWVESLRGFEQERVGLADLHPDVFATAPRLDILHQVAMWQKNFKRISYAKTKTRAEVRGGGRKPWPQKGTGRARHGSIRSPLWRGGGVAHGPRGPTSYYYMLPMKVRALGLKVALTVKLAQDDLHIMDSLELPTGDPQYLTELAHYRRWGDSVLLVDLTHEEMPQSIVEATSRLKTFNLIPAVGLNVHSMLKHQTLVLTLPTVAFLEDKLLWQDSRYRPLYPFSLPYSDFP 3j7y H 3.40 BS01 NUC A 1 W60 K61 P63 L64 G66 H74 R75 R76 L82 D85 K87 H88 N121 W8 K9 P11 L12 G14 H22 R23 R24 L30 D33 K35 H36 N69 Q9BYD2 25278503 TVIVERWWKVPLAGEGRKPRLHRRHRVYKLVEDTKHRPKENLELILTQSVENVGVRGDLVSVKKSLGRNRLLPQGLAVYASPENKKLFEEEKLLR 3j7y I 3.40 BS01 NUC A 1 S30 K31 V33 T34 R35 R38 H41 F42 Q43 K46 K109 R113 K124 V125 F126 P127 N128 G149 H150 S1 K2 V4 T5 R6 R9 H12 F13 Q14 K17 K70 R74 K85 V86 F87 P88 N89 G110 H111 Q7Z7H8 25278503 SKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPGLIRLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFLEDSKYQNLLPLFVGHNMLLVSEEPKVKEMVRILRTVPFLPLLGGCIDDTILSRQGFINYSKL 3j7y J 3.40 BS01 NUC A 1 R21 I23 V38 Q41 R42 T86 V87 S88 K92 K99 G100 A101 R102 Q103 T104 K106 A129 F130 A131 L132 D134 S139 R142 S143 G146 S147 S150 L151 R4 I6 V21 Q24 R25 T69 V70 S71 K75 K82 G83 A84 R85 Q86 T87 K89 A112 F113 A114 L115 D117 S122 R125 S126 G129 S130 S133 L134 Q9Y3B7 25278503 GVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVK 3j7y K 3.40 BS01 NUC A 1 P27 P28 G29 K30 A49 L50 S68 K71 K75 S78 H80 Y83 P84 G85 F87 A107 Y109 G110 M111 K114 N115 L116 H117 R118 R119 Y176 R177 P26 P27 G28 K29 A48 L49 S67 K70 K74 S77 H79 Y82 P83 G84 F86 A106 Y108 G109 M110 K113 N114 L115 H116 R117 R118 Y175 R176 Q9BYD1 25278503 SSFSRAPQQWATFARIWYLLDGKMQPPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHLRDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEYIPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL 3j7y L 3.40 BS01 NUC A 1 A31 Q33 K34 M35 T36 R37 H52 R53 R56 I58 H59 Y61 K63 N64 L74 K81 C90 M91 P92 R95 N103 A1 Q3 K4 M5 T6 R7 H22 R23 R26 I28 H29 Y31 K33 N34 L44 K51 C60 M61 P62 R65 N73 Q6P1L8 25278503 AIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQKKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKREGEYSKVLAIAQNFV 3j7y M 3.40 BS01 NUC A 1 L24 A25 N26 L27 K28 P29 N30 G32 S33 K34 K35 P36 E37 R38 R39 R41 G42 R43 R44 R45 R47 K48 C49 G50 R51 G52 H53 K54 G55 E56 R57 Q58 R59 T61 R62 R64 F67 E68 G69 G70 Q71 T72 Y75 I76 R77 I78 P79 K80 H87 S88 F89 R100 Y103 R109 T128 Q130 L132 K133 R134 P192 R196 Q198 L15 A16 N17 L18 K19 P20 N21 G23 S24 K25 K26 P27 E28 R29 R30 R32 G33 R34 R35 R36 R38 K39 C40 G41 R42 G43 H44 K45 G46 E47 R48 Q49 R50 T52 R53 R55 F58 E59 G60 G61 Q62 T63 Y66 I67 R68 I69 P70 K71 H78 S79 F80 R91 Y94 R100 T119 Q121 L123 K124 R125 P183 R187 Q189 Q9P015 25278503 ARALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLIDLGRVDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIEVQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPIPKRMLPPEELVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKMLCTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS 3j7y N 3.40 BS01 NUC A 1 R63 R64 P66 K67 N68 L69 I72 R73 Y96 G100 H101 M104 R111 K134 G137 R139 M140 G141 G142 G143 K144 G145 Q178 H181 K182 L183 P184 R227 K228 V229 S231 P232 Y233 K244 R17 R18 P20 K21 N22 L23 I26 R27 Y50 G54 H55 M58 R65 K88 G91 R93 M94 G95 G96 G97 K98 G99 Q132 H135 K136 L137 P138 R181 K182 V183 S185 P186 Y187 K198 Q9NX20 25278503 KPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV 3j7y O 3.40 BS01 NUC A 1 I9 S10 H11 G12 R13 V14 R16 R17 L20 G21 P22 H27 N31 L32 G35 H39 I42 E43 A47 R48 T81 E82 L115 D116 R117 A118 K119 I1 S2 H3 G4 R5 V6 R8 R9 L12 G13 P14 H19 N23 L24 G27 H31 I34 E35 A39 R40 T73 E74 L107 D108 R109 A110 K111 Q9NRX2 25278503 ISHGRVFRRMGLGPESRIHLLRNLLTGLVRHERIEAPWARVDEMRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYKDQTGGYTRMLQIPNRSLDRAKMAVIEYKGNCLPPLPLPRRDSHLTLLNQLLQGLRQDLRQSQ 3j7y P 3.40 BS01 NUC A 1 R65 R172 Y178 E179 R24 R126 Y132 E133 A8K9D2 25278503 AVAPEFTNRNPRNLELLSVARKERGWRTVFPSREFWHRLRVIRTQHHVEALVEHQNGKVVVSASTREWAIKKHNVVACESIGRVLAQRCLEAGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIYE 3j7y P 3.40 BS02 NUC B 1 T85 Q86 H87 H88 R107 W109 K112 N120 V121 W150 S154 D155 S156 T44 Q45 H46 H47 R66 W68 K71 N74 V75 W104 S108 D109 S110 A8K9D2 25278503 AVAPEFTNRNPRNLELLSVARKERGWRTVFPSREFWHRLRVIRTQHHVEALVEHQNGKVVVSASTREWAIKKHNVVACESIGRVLAQRCLEAGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIYE 3j7y Q 3.40 BS01 NUC A 1 R83 R84 G85 R86 Q139 S141 R143 G146 T148 E165 K231 R232 R235 W260 R10 R11 G12 R13 Q66 S68 R70 G73 T75 E92 K143 R144 R147 W172 P49406 25278503 RFLSPEFIPRRGRTDPLKFQIERKDMLERRKVLHIPEFYVGSILRVTTADPYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRVQEIQVVKLEKRLDDSLLYLRDALPEYQKVPVNELKVKMKPKPWSKRWERPNFNIKGIRFDLCLTEQQMKEAQKWNQPWLEFDMMREYDTSKIEAAIWKEIEASKRS 3j7y R 3.40 BS01 NUC A 1 L10 R11 N12 R13 V14 T15 R17 R20 H30 F31 R32 R34 K35 R37 C38 Y39 R40 L41 V43 R44 I47 R48 A49 K52 C53 A56 R57 Y58 L59 K60 K61 K62 M64 R65 W68 K82 Y83 P84 G88 N98 R99 K100 F128 L1 R2 N3 R4 V5 T6 R8 R11 H21 F22 R23 R25 K26 R28 C29 Y30 R31 L32 V34 R35 I38 R39 A40 K43 C44 A47 R48 Y49 L50 K51 K52 K53 M55 R56 W59 K73 Y74 P75 G79 N89 R90 K91 F119 Q9BYC9 25278503 LRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYLKKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYEPKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH 3j7y S 3.40 BS01 NUC A 1 P60 W61 A102 S103 R104 N118 R169 I171 R173 F174 R175 K176 R177 K178 F180 K181 K182 K183 R184 T188 P12 W13 A54 S55 R56 N70 R121 I123 R125 F126 R127 K128 R129 K130 F132 K133 K134 K135 R136 T140 Q7Z2W9 25278503 GYVPKTSLSSPPWPEVVLPDPVEETRHHAEVVKKVNEMIVTGQYGRLFAVVHFASRQWKVTSEDLILIGNELDLACGERIRLEKVLLVGADNFTLLGKPLLGKDLVRVEATVIEKTESWPRIIMRFRKRKNFKKKRIVTTPQTVLRINSIEIAPCL 3j7y T 3.40 BS01 NUC A 1 I47 S48 R49 K50 W51 K53 K54 K56 R78 K81 Y82 S83 K84 D85 K86 W88 R95 D110 K111 K112 T146 G148 R149 Q151 K154 R157 Y158 H159 G160 R161 G162 R163 F164 G165 I166 M167 E168 K169 V170 H173 F175 S205 R206 T207 H210 I1 S2 R3 K4 W5 K7 K8 K10 R32 K35 Y36 S37 K38 D39 K40 W42 R49 D64 K65 K66 T100 G102 R103 Q105 K108 R111 Y112 H113 G114 R115 G116 R117 F118 G119 I120 M121 E122 K123 V124 H127 F129 S159 R160 T161 H164 E7ESL0 25278503 ISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKLIRGMSIDQALAQLEFNDKKGAKIIKEVLLEAQDMAVRDHNVEFRSNLYIAESTSGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPPEPPKTAVAHAKEYIQQLRSRTIVHTL 3j7y U 3.40 BS01 NUC A 1 N4 G32 V33 Q35 Q41 R43 R50 R69 T70 R71 V72 Q73 H74 S76 N77 K78 R79 R80 R83 N84 V85 K89 K93 Y96 N3 G31 V32 Q34 Q40 R42 R49 R68 T69 R70 V71 Q72 H73 S75 N76 K77 R78 R79 R82 N83 V84 K88 K92 Y95 Q16540 25278503 ARNVVYPLYRLGGPQLRVFRTNFFIQLVRPGVAQPEDTVQFRIPMEMTRVDLRNYLEGIYNVPVAAVRTRVQHGSNKRRDHRNVRIKKPDYKVAYVQLAHGQTFTFPDLFP 3j7y V 3.40 BS01 NUC A 1 H18 R20 G22 M23 S24 A30 R33 K34 R40 R41 R42 P43 R83 W85 H94 R96 S111 A113 H4 R6 G8 M9 S10 A16 R19 K20 R26 R27 R28 P29 R66 W68 H77 R79 S94 A96 Q96A35 25278503 LPPHYRYGMSPPGSVADKRKNPPWIRRRPVVVSDEDWYLFCGDTVEILEGKDAGKQGKVVQVIRQRNWVVVGGLNTHYRYIGKTMDYRGTMIPSEAPLLHRQVKLVDPMDRKPTEIEWRFTEAGERVRVSTRSGRIIPKPETWIDGPKDTSVEDALERTYVPCLKTLQEEVMEAMGIKETRKYKKVYWY 3j7y W 3.40 BS01 NUC A 1 L42 G43 G44 K45 S46 S47 G48 R49 R50 Q51 I53 K54 M56 E57 H59 A63 G64 N65 I66 R71 R74 W75 G84 K85 N86 C88 Y90 Y99 K101 L1 G2 G3 K4 S5 S6 G7 R8 R9 Q10 I12 K13 M15 E16 H18 A22 G23 N24 I25 R30 R33 W34 G43 K44 N45 C47 Y49 Y58 K60 Q9P0M9 25278503 LGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCLYALEEGIVRYTKEVYVPHPRNTEAVDLITRLPKGAVLYKTFVHVVPAKPEGTFKLVAML 3j7y X 3.40 BS01 NUC A 1 L3 H4 K5 Y6 L14 K55 N56 E60 Y70 L87 G88 Y91 A92 N93 K96 L97 S98 K99 R100 L101 K102 K103 V104 W105 K106 P107 Q108 F110 R112 M129 L2 H3 K4 Y5 L13 K54 N55 E59 Y69 L86 G87 Y90 A91 N92 K95 L96 S97 K98 R99 L100 K101 K102 V103 W104 K105 P106 Q107 F109 R111 M128 Q4TT38 25278503 PLHKYPVWLWKRLQLREGICSRLPGHYLRSLEEERTPTPVHYRPHGAKFKINPKNGQRERVEDVPIPIYFPPESQRGLWGGEGWILGQIYANNDKLSKRLKKVWKPQLFEREFYSEILDKKFTVTVTMRTLDLIDEAYGLDFYILKASGEDLCSKFGMDLKRGMLLRLARQDPQLHPEDPERRAAIYDKYKEFAIPEEEAEWVGLTLEEAIEKQRLLEEKDPVPLFKIYVAELIQQLQQQALS 3j7y Y 3.40 BS01 NUC A 1 Q117 K120 R121 R123 R162 R164 W168 I172 I176 W178 K180 K182 W184 V185 I186 L190 K192 R193 R196 K197 R198 L202 R213 R216 R222 N225 L226 R228 K229 K230 K232 Q55 K58 R59 R61 R100 R102 W106 I110 I114 W116 K118 K120 W122 V123 I124 L128 K130 R131 R134 K135 R136 L140 R151 R154 R160 N163 L164 R166 K167 K168 K170 Q9HD33 25278503 GLEEFFDDPKNWGQEKVKSGAAWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLDKVVDSMDALDKVVQEREDALRLLQTGQERARPGAWRRDIFGRIIWHKFKQWVIPWHLNKRYNRKRFFALPYVDHFLRLEREKRARIKARKENLERKKAKILLKKF 3j7y Z 3.40 BS01 NUC A 1 K35 F36 T37 R38 S39 R40 R71 K73 S74 R76 R77 P79 Y80 W81 K83 I85 M88 L89 A94 H95 H100 K101 S105 V106 K109 K1 F2 T3 R4 S5 R6 R37 K39 S40 R42 R43 P45 Y46 W47 K49 I51 M54 L55 A60 H61 H66 K67 S71 V72 K75 Q8TCC3 25278503 KFTRSRIPEKVFQASPEDHEKYGGDPQNPHKLHIVTRIKSTRRRPYWEKDIIKMLGLEKAHTPQVHKNIPSVNAKLKVVKHLIRIKPLKLPQGLPAEENMSNTCLKSTGELVVQWHLKPV 3j7y 0 3.40 BS01 NUC A 1 A79 A80 P81 K82 N83 R84 R85 T86 I87 V89 N90 R91 C92 R93 R94 R95 N96 P97 Q98 K99 N106 H120 R138 R139 I141 G142 F149 A1 A2 P3 K4 N5 R6 R7 T8 I9 V11 N12 R13 C14 R15 R16 R17 N18 P19 Q20 K21 N28 H42 R60 R61 I63 G64 F71 Q9BYC8 25278503 AAPKNRRTIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHVLCAYCYEKVCKETAEIRRQIGKQEGGPFKAPTIETVVLYTGRIIERDRKRPSWFT 3j7y 0 3.40 BS02 ZN 0 1 C110 E112 C113 C123 C126 C32 E34 C35 C45 C48 Q9BYC8 25278503 AAPKNRRTIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHVLCAYCYEKVCKETAEIRRQIGKQEGGPFKAPTIETVVLYTGRIIERDRKRPSWFT 3j7y 1 3.40 BS01 NUC A 1 K14 N15 R19 C29 F30 N31 T32 L41 L43 L44 H45 Y46 R53 I62 R63 K1 N2 R6 C16 F17 N18 T19 L28 L30 L31 H32 Y33 R40 I49 R50 O75394 25278503 KNILVRMVSEAGTGFCFNTKRNRLREKLTLLHYDPVVKQRVLFVEKKKIRSL 3j7y 2 3.40 BS01 NUC A 1 G50 N51 E52 Y53 Q54 P55 S56 N57 K59 R60 K61 N62 K63 H64 G65 W66 V67 R69 A74 V78 R81 R82 K85 R87 K88 L90 H92 G1 N2 E3 Y4 Q5 P6 S7 N8 K10 R11 K12 N13 K14 H15 G16 W17 V18 R20 A25 V29 R32 R33 K36 R38 K39 L41 H43 Q9BQ48 25278503 GNEYQPSNIKRKNKHGWVRRLSTPAGVQVILRRMLKGRKSLSH 3j7y 3 3.40 BS01 NUC A 1 L94 T95 F97 S98 A99 R100 K101 K103 R104 K105 T106 V107 K108 A109 R113 H118 R124 K126 A127 G128 K131 K132 L133 W134 K135 K136 R140 K142 R143 L144 R145 K152 T153 Q154 K156 S164 F165 W166 R168 R169 W171 D182 V188 L1 T2 F4 S5 A6 R7 K8 K10 R11 K12 T13 V14 K15 A16 R20 H25 R31 K33 A34 G35 K38 K39 L40 W41 K42 K43 R47 K49 R50 L51 R52 K59 T60 Q61 K63 S71 F72 W73 R75 R76 W78 D89 V95 Q9NZE8 25278503 LTYFSARKGKRKTVKAVIDRFLRLHCGLWVRRKAGYKKKLWKKTPARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYVDDPYQKYHDRTNLKV 3j7y 4 3.40 BS01 NUC A 1 K67 N68 K69 T70 V71 K74 R75 K77 L81 V82 K83 R84 R85 G86 R87 W88 Y89 Y91 P96 R97 K99 R101 Q102 K1 N2 K3 T4 V5 K8 R9 K11 L15 V16 K17 R18 R19 G20 R21 W22 Y23 Y25 P30 R31 K33 R35 Q36 Q9P0J6 25278503 KNKTVLKKRCKDCYLVKRRGRWYVYCKTHPRHKQRQ 3j7y 4 3.40 BS02 ZN 0 1 C76 C79 C92 H98 C10 C13 C26 H32 Q9P0J6 25278503 KNKTVLKKRCKDCYLVKRRGRWYVYCKTHPRHKQRQ 3j7y 5 3.40 BS01 NUC A 1 Y31 E32 W33 G34 V35 R36 S37 F66 P68 W69 R72 W78 Y82 P85 R86 F87 Y88 R89 S90 P91 L93 H96 P97 L98 I106 H108 R110 R112 I170 R173 R223 D264 H266 C268 I270 L299 R300 P301 H302 Q305 Q308 R350 H385 F386 W387 C388 L389 P390 Y1 E2 W3 G4 V5 R6 S7 F36 P38 W39 R42 W48 Y52 P55 R56 F57 Y58 R59 S60 P61 L63 H66 P67 L68 I76 H78 R80 R82 I132 R135 R185 D226 H228 C230 I232 L261 R262 P263 H264 Q267 Q270 R312 H344 F345 W346 C347 L348 P349 Q9BZE1 25278503 YEWGVRSTRKSEPPPLDRVYEIPGLEPITFAGKMHFVPWLARPIFPPWDRGYKDPRFYRSPPLHEHPLYKDQACYIFHHRCRLLEGVKQALWLTKTKLIEGLPEKVLSLVDQDECVLNVISHARLWQTTEEIPKRETYCPVIVDNLIQLCKSQILKHPSLARRICVQNSTFSATWNRESLLLQVRGSGGARLSTKDPLPTIASREEIEATKNHVLETFYPISPIIDLHECNIYDVKNDTGFQEGYPYPYPHTLYLLDKANLRPHRLQPDQLRAKMILFAFGSALAQARLLYGNDAKVLEQPVVVQSVGTDGRVFHFLVFQLNTTDLDGVKNLAWVDSDQLLYQHFWCLPVIVEPVGPVGFKPETFRKFLALYLHGA 3j7y 6 3.40 BS01 NUC A 1 R27 R28 H351 P352 R356 F357 H359 R360 R364 R368 T376 G378 I379 Y380 R1 R2 H296 P297 R301 F302 H304 R305 R309 R313 T321 G323 I324 Y325 Q96DV4 25278503 RRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYREYFGRTQQLLERKQAIQELRANVEERAARTASVPLDAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQAPEVTYEAELWTLLLTSLDGHLLEPDAEYLHWLLTNIPGNRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSPSPCYQLAQRTFRTFDFYKKHQETMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHEPTYGIY 3j7y 6 3.40 BS02 NUC B 1 R52 S53 R56 R59 R26 S27 R30 R33 Q96DV4 25278503 RRTPPLGPMPNSDIDLSNLERLEKYRSFDRYRRRAEQEAQAPHWWRTYREYFGRTQQLLERKQAIQELRANVEERAARTASVPLDAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGATFVPRVPLHVAYAVGEDDLMPVYCGNEVTPTEAAQAPEVTYEAELWTLLLTSLDGHLLEPDAEYLHWLLTNIPGNRVAEGQVTCPYLPPFPARGSGIHRLAFLLFKQDQPIDFSPSPCYQLAQRTFRTFDFYKKHQETMTPAGLSFFQCRWDDSVTYIFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHEPTYGIY 3j7y 8 3.40 BS01 NUC B 1 S78 K81 Q82 R85 R89 S16 K19 Q20 R23 R27 Q9NQ50 25278503 TFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPKLHAEAIK 3j7y 9 3.40 BS01 NUC A 1 D16 R17 M18 W21 S23 K24 R25 P27 R28 S29 F30 R31 G32 R33 K34 G35 R36 A38 K39 G40 I41 L44 T45 S46 W48 F50 V51 Q52 D2 R3 M4 W7 S9 K10 R11 P13 R14 S15 F16 R17 G18 R19 K20 G21 R22 A24 K25 G26 I27 L30 T31 S32 W34 F36 V37 Q38 Q8IXM3 25278503 ADRMSKWTSKRGPRSFRGRKGRGAKGIGFLTSGWRFVQIKEMVPEFVVPDLTGFKLKPYVSYLAPESEETPLTAAQLFSEAVAPAIEKDGFEPTQEGKLFQLYPRNFLR 3j7y a 3.40 BS01 NUC A 1 K120 H121 Y124 P125 H126 G127 R128 Y129 H130 R133 K134 P138 K17 H18 Y21 P22 H23 G24 R25 Y26 H27 R30 K31 P35 Q9Y6G3 25278503 EEGPMIEQLSKMFFTTKHRWYPHGRYHRCRKNLNPPKDR 3j7y b 3.40 BS01 NUC A 1 T2 A3 R4 D36 A38 S39 P69 C70 C71 V72 R74 H90 C91 R114 R116 K117 P118 T1 A2 R3 D35 A37 S38 P68 C69 C70 V71 R73 H89 C90 R113 R115 K116 P117 Q8N983 25278503 TARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQ 3j7y c 3.40 BS01 NUC A 1 V31 K33 G34 F35 R36 F39 L45 Q48 R49 R52 V1 K3 G4 F5 R6 F9 L15 Q18 R19 R22 Q9H9J2 25278503 VKKGFRAAFRFQKELERQRLLRCPPPPVRRSEKPNWDYHAEIQAFGHRLQENFSLDLLKTAFVNSCYIKSEEAKRQQLKSNQELSEQGTSFSQTCLTQFLEDEYPDMPTEGIKNLVDFLTGEEVVCHVARNLAVEQLTLSEEFPVPPAVLQQTFFAVIGALLQSSGPERTALFIRDFLITQMTGKELFEMWKIINPMGLLVEELKKRNVSAPESRLTRQSGGTTALPLYFVGLYCDKKLIAEGPGETVLVAEEEAARVALRKLYGFTENRRPWNY 3j7y e 3.40 BS01 NUC B 1 F171 F173 F71 F73 Q9H2W6 25278503 DRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYLKPKYLAQVRRFVSD 3j7y f 3.40 BS01 NUC A 1 Y48 K49 T50 K51 H54 G55 I56 G57 K58 Y59 K60 Y1 K2 T3 K4 H7 G8 I9 G10 K11 Y12 K13 Q96GC5 25278503 YKTKPTHGIGKYKHLIDMTLAESYAQYVHNLCNSLSIKVEESYAMPLTTHERVVQISGLSATFAEIFLEIIQSGVRLSVGGGGGGGGGGGGGGGG 3j7y f 3.40 BS02 NUC B 1 Q108 H111 N115 S124 R155 Q26 H29 N33 S42 R52 Q96GC5 25278503 YKTKPTHGIGKYKHLIDMTLAESYAQYVHNLCNSLSIKVEESYAMPLTTHERVVQISGLSATFAEIFLEIIQSGVRLSVGGGGGGGGGGGGGGGG 3j7y g 3.40 BS01 NUC A 1 S89 R90 M91 N93 Y97 K98 I100 T101 H102 G103 N104 R105 R111 K112 T144 K150 S52 R53 M54 N56 Y60 K61 I63 T64 H65 G66 N67 R68 R74 K75 T107 K113 Q13405 25278503 FVESVDEYQFVERLLPATRIPDPPKHEHYPTPSGWQPPRDPPPNLPYFVRRSRMHNIPVYKDITHGNRQMTVIRKVEGDIWALQKDVEDFLSPLLGKTPVTQVNEVTGTLRIKGYFDQELKAWLLEKGF 3j7y i 3.40 BS01 NUC A 1 I32 R35 L36 R46 R51 G61 F66 K68 H69 P70 R75 P77 W79 N86 E87 R93 K96 M97 H108 K112 R113 R115 Y116 L117 Y118 K119 H120 F121 R123 H124 G125 K126 F127 I1 R4 L5 R15 R20 G30 F35 K37 H38 P39 R44 P46 W48 N55 E56 R62 K65 M66 H77 K81 R82 R84 Y85 L86 Y87 K88 H89 F90 R92 H93 G94 K95 F96 Q4U2R6 25278503 IGIRLTLPPPKVVDRWNEKRAMFGVYDNIGILGNFEKHPKELIRGPIWLRGWKGNELQRCIRKRKMVGSRMFADDLHNLNKRIRYLYKHFNRHGKF 3j7y j 3.40 BS01 NUC A 1 G24 G25 Q26 R28 A35 N36 P37 S38 G39 M60 K61 G62 R66 R76 G1 G2 Q3 R5 A12 N13 P14 S15 G16 M37 K38 G39 R43 R53 A8K7J6 25278503 GGQWRLQQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAERETFARRVVLLSQEMDAGLQAWQLRQQKLQEEQRKQENA 3j7y o 3.40 BS01 NUC A 1 R9 G10 R11 I12 P13 G14 R15 Q16 W17 I18 G19 K20 H21 R22 R23 R25 F26 S28 R30 A31 N34 R37 R38 R56 E59 R60 G61 H62 A63 A64 R66 R67 F71 I74 K75 A78 K81 R86 H94 K100 R1 G2 R3 I4 P5 G6 R7 Q8 W9 I10 G11 K12 H13 R14 R15 R17 F18 S20 R22 A23 N26 R29 R30 R48 E51 R52 G53 H54 A55 A56 R58 R59 F63 I66 K67 A70 K73 R78 H86 K92 Q9BQC6 25278503 RGRIPGRQWIGKHRRPRFVSLRAKQNMIRRLEIEAENHYWLSMPYMTREQERGHAAVRRREAFEAIKAAATSKFPPHRFIADQLDHLNVTKKWS 3j7y r 3.40 BS01 NUC A 1 N82 D84 R94 H96 G98 M99 L100 P101 R102 H112 E116 K120 H123 R124 R132 P133 Y150 L151 R153 W154 A155 G157 S158 K160 K165 G166 R168 W169 R171 R173 P179 R182 S188 R189 W192 K193 L194 Y195 H196 N43 D45 R55 H57 G59 M60 L61 P62 R63 H73 E77 K81 H84 R85 R93 P94 Y100 L101 R103 W104 A105 G107 S108 K110 K115 G116 R118 W119 R121 R123 P129 R132 S138 R139 W142 K143 L144 Y145 H146 Q9NVS2 25278503 FREVVETTIIEGRITATPKESPNPPNPSGQCPICRWNLKHKYNYDDVLLLSQFIRPHGGMLPRKITGLCQEEHRKIEECVKMAHRAGLLPNHRPRQLNRYLTRWAPGSVKPIYKKGPRWNRVRMPVGSPLLRDNVCYSRTPWKLYH 3j7y r 3.40 BS02 ZN r 1 C70 C73 C108 C31 C34 C69 Q9NVS2 25278503 FREVVETTIIEGRITATPKESPNPPNPSGQCPICRWNLKHKYNYDDVLLLSQFIRPHGGMLPRKITGLCQEEHRKIEECVKMAHRAGLLPNHRPRQLNRYLTRWAPGSVKPIYKKGPRWNRVRMPVGSPLLRDNVCYSRTPWKLYH 3j7y s 3.40 BS01 NUC A 1 A49 S50 T52 A53 D54 S55 K56 A57 R59 R62 I63 R65 W66 R81 I82 K85 M86 Q87 F88 M89 Y94 T97 F98 R160 R162 H164 R165 Y166 R219 G220 H221 R222 R223 R225 K270 P272 F274 Q277 R310 R313 A9 S10 T12 A13 D14 S15 K16 A17 R19 R22 I23 R25 W26 R41 I42 K45 M46 Q47 F48 M49 Y54 T57 F58 R100 R102 H104 R105 Y106 R159 G160 H161 R162 R163 R165 K210 P212 F214 Q217 R250 R253 Q9NP92 25278503 VARYPPIVASMTADSKAARLRRIERWQATVHAAESVDEKLRILTKMQFMKYMVYPQTFALNADRWYQYFTKTVFLSGLPAALRAVACDCLLQEHFYLRRRRRVHRYEESEVISLPFLDQLVSTLVGLLSPHNPALAAAALDYRCPVHFYWVRGEEIIPRGHRRGRIDDLRYQIDDKPNNQIRISKQLAEFVPLDYSVPIEIPTIKCKPDKLPLFKRQYENHIFVGSKTADPCCYGHTQFHLLPDKLRRERLLRQNCADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCYQLNTLALTTQADQNNPRKNICWGTQSKPLYETIEDNDVKGFNDDVLLQIVHFLLNRPK 3wh0 A 1.60 BS01 O4B A 1 Y23 W34 Y17 W28 5.2.1.8 Q13526 25287606 LPPGWEKAMSRSSGRVYYFNHITNASQWERPSEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 3wh0 A 1.60 BS02 O4B A 2 W73 S114 K117 W55 S96 K99 5.2.1.8 Q13526 25287606 LPPGWEKAMSRSSGRVYYFNHITNASQWERPSEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE 3whm A 1.85 BS01 HEM A 1 Y42 F43 H45 H58 K61 V62 A65 L66 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 Y42 F43 H45 H58 K61 V62 A65 L66 L83 L86 H87 L91 V93 N97 F98 L101 V132 L136 P69905 25287606 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 3whm A 1.85 BS02 O4B A 1 F33 L34 P37 K40 F33 L34 P37 K40 P69905 25287606 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 3whm B 1.85 BS02 O4B B 1 P58 K59 A62 P57 K58 A61 P68871 25287606 HLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHK 3whm E 1.85 BS01 HEM E 1 Y42 F43 H45 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H45 H58 K61 A65 L83 L86 H87 L91 V93 N97 F98 L101 L136 P69905 25287606 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 3whm E 1.85 BS02 O4B E 1 T8 K11 A71 V73 D74 T8 K11 A71 V73 D74 P69905 25287606 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 3whm E 1.85 BS03 O4B E 2 L34 P37 K40 L48 L34 P37 K40 L48 P69905 25287606 VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKY 3wj4 A 1.95 BS01 TBY A 1 I281 F282 C285 Y327 V339 I341 F363 M364 H449 I63 F64 C67 Y109 V121 I123 F145 M146 H231 P37231 GSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPFVIYDMNSLMMGEDKISKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYK 3wj4 B 1.95 BS01 TBY B 1 C285 Y327 V339 L353 F363 M364 H449 C73 Y115 V127 L141 F151 M152 H237 P37231 GPLGSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPFVIYDMNSLMMGEDKIKFKHKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDHPLLQEIYKD 3wj5 A 1.89 BS01 T9T A 1 F282 C285 Q286 S289 Y327 L330 F360 F363 M364 K367 H449 L453 L469 Y473 F64 C67 Q68 S71 Y109 L112 F142 F145 M146 K149 H231 L235 L251 Y255 P37231 GSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPFVIYDMNSLMMGEDKISKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 3wj5 B 1.89 BS01 T9T B 1 C285 R288 S289 I326 L330 M334 V339 I341 M348 M364 C73 R76 S77 I114 L118 M122 V127 I129 M136 M152 P37231 GPLGSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPFVIYDMNSLMMGEDKIKFKHKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTEHPLLQEIYKD 3wqj A 1.80 BS01 RET A 1 W91 T95 M123 W143 S146 T147 F150 W187 Y190 P191 W194 D217 K221 W91 T95 M123 W143 S146 T147 F150 W187 Y190 P191 W194 D217 K221 P29563 QAGFDLLNDGRPETLWLGIGTLLMLIGTFYFIARGWGVTDKEAREYYAITILVPGIASAAYLAMFFGIGVTEVELASGTVLDIYYARYADWLFTTPLLLLDLALLAKVDRVTIGTLIGVDALMIVTGLIGALSKTPLARYTWWLFSTIAFLFVLYYLLTSLRSAAAKRSEEVRSTFNTLTALVAVLWTAYPILWIVGTEGAGVVGLGIETLAFMVLDVTAKVGFGFVLLRSRAI 3wqj A 1.80 BS02 22B A 1 F29 I32 G35 W36 R44 Y47 A48 I51 L52 F29 I32 G35 W36 R44 Y47 A48 I51 L52 P29563 QAGFDLLNDGRPETLWLGIGTLLMLIGTFYFIARGWGVTDKEAREYYAITILVPGIASAAYLAMFFGIGVTEVELASGTVLDIYYARYADWLFTTPLLLLDLALLAKVDRVTIGTLIGVDALMIVTGLIGALSKTPLARYTWWLFSTIAFLFVLYYLLTSLRSAAAKRSEEVRSTFNTLTALVAVLWTAYPILWIVGTEGAGVVGLGIETLAFMVLDVTAKVGFGFVLLRSRAI 3wur A 1.45 BS01 O4B A 1 R124 K125 E131 R122 K123 E129 Q9K0P4 25287606 ALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQ 3wur A 1.45 BS02 O4B A 2 D43 T47 A50 Y74 R77 P79 D41 T45 A48 Y72 R75 P77 Q9K0P4 25287606 ALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQ 3wur A 1.45 BS03 O4B B 1 L27 Y53 Y71 Y74 L25 Y51 Y69 Y72 Q9K0P4 25287606 ALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQ 3wur A 1.45 BS04 O4B B 2 A68 A114 A66 A112 Q9K0P4 25287606 ALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQ 3wur A 1.45 BS05 O4B B 3 E73 Y103 G107 K108 E111 E71 Y101 G105 K106 E109 Q9K0P4 25287606 ALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQ 3wur B 1.45 BS02 O4B B 1 L27 L38 Y53 Y71 Y74 L27 L38 Y53 Y71 Y74 Q9K0P4 25287606 MTALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQA 3wur B 1.45 BS03 O4B B 4 D43 H46 T47 A50 Y74 R77 P79 D43 H46 T47 A50 Y74 R77 P79 Q9K0P4 25287606 MTALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQA 3wur B 1.45 BS04 O4B B 5 E73 Y103 G107 K108 E73 Y103 G107 K108 Q9K0P4 25287606 MTALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDDQHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKALYEQHGKTIETLADGGADIPSLRKQFPEFEEWDGAYYEAAEQDLPLLAEHIQSNWETFAHIGQA 3wxc A 2.10 BS03 C93 A 1 V31 F51 H79 S80 D81 H139 C158 K161 G166 N167 H197 V28 F48 H76 S77 D78 H136 C155 K158 G163 N164 H194 3.5.2.6 Q79MP6 25246278 LPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNES 4c7u A 1.95 BS01 MN A 1 H26 H74 D163 H167 H27 H75 D164 H168 1.15.1.1 O81235 MTFTLPDLPYDYGALEPAISGEIMQIHHQKHHQAYVTNYNNALEQLDQAVNKGDASTVVKLQSAIKFNGGGHVNHSIFWKNLAPSSEGGGEPPKGSLGSAIDAHFGSLEGLVKKMSAEGAAVQGSGWVWLGLDKELKKLVVDTTANQDPLVTKGGSLVPLVGIDVWEHAYYLQYKNVRPEYLKNVWKVINWKYASEVYEKENN 4c9f A 2.60 BS02 GQ2 A 1 E285 N287 N288 E292 E296 S305 L309 K311 E95 N97 N98 E102 E106 S115 L119 K121 Q8CJ91 LCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPC 4c9f B 2.60 BS02 GQ2 B 1 P251 E285 N287 N288 E296 N303 D304 S305 K311 P61 E95 N97 N98 E106 N113 D114 S115 K121 Q8CJ91 LCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCT 4c9f C 2.60 BS02 GQ4 C 1 Q213 K249 G250 P251 E285 N287 N288 E292 E296 S305 L309 K311 Q23 K59 G60 P61 E95 N97 N98 E102 E106 S115 L119 K121 Q8CJ91 LCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPC 4c9f D 2.60 BS02 GQ1 D 1 N234 S235 D236 E237 R276 N45 S46 D47 E48 R87 Q8CJ91 KLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCT 4c9f D 2.60 BS03 GQ1 D 2 R276 K279 R87 K90 Q8CJ91 KLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCT 4c9f D 2.60 BS04 GQ1 D 3 N205 N234 S235 E238 K316 N16 N45 S46 E49 K127 Q8CJ91 KLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCT 4cag A 2.50 BS01 CA A 1 H333 H369 D371 E392 H328 H364 D366 E387 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS02 CA A 2 D123 N562 V563 G564 N566 D118 N557 V558 G559 N561 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS03 CA A 3 D466 D468 Q470 E472 D461 D463 Q465 E467 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS04 CA A 4 D427 D429 Y432 G434 E436 D422 D424 Y427 G429 E431 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS05 CA A 5 D192 D194 D196 K198 E200 D187 D189 D191 K193 E195 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS06 CA A 6 D341 D343 E347 D356 H357 D336 D338 E342 D351 H352 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS08 CA A 8 N377 D379 R382 G384 E386 N372 D374 R377 G379 E381 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS09 CA A 9 D128 L129 D130 D132 Q134 E136 K164 D123 L124 D125 D127 Q129 E131 K159 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4cag A 2.50 BS10 CA A 10 D513 L515 G516 D517 R519 E521 D508 L510 G511 D512 R514 E516 4.2.2.-,4.2.2.23 Q65KY4 AQARQMESLNRGLVAVKTGNGVFVSWRLLGTEPSSVSFNVYRNGKKLNGSPITSSTNYQDAGGDLNAVYQVRAVLNGREQAPSESVGVLNKQYKSVPLQKPAGGKTPDGVSYTYSANDASVGDLDGDGQYEIILKWDPSNSKDNSQDGYTGDVLIDAYKLDGTMMWRINLGKNIRAGAHYTQFLVYDFDGDGKAEIAMKTADGTKDGKGKVIGNANADYRNAQGRILSGPEYLTVFKGDTGAELTTVNYEPARGNVADWGDSYGNRVDRFLAGVAYLDGERPSFVMARGYYTRTVLVAYNFRGGKLTKLWTFDSDAPGNGAYAGQGNHSLSVADVDGDGKDEIIYGAMAVDHDGKGLYSTGWGHGDAMHTGNLDPSRPGLEVFQVHENSNSPYGLSFRDAKTGKIIWGVHAGKDVGRGMAADIDPRYEGAEVWANGSLYTAKGVKIGNTLPSSTNFGIWWDGDLQRELLDSNRIDKWDYQNSRTVNLLTASGASANNGTKATPSLQADILGDWREEVVWRAEDSSELRIYTTTDVTEHRMYTLMHDAVYRLGIAWQNVGYNQPPHTGFYLGEGMQTPEKPNIYT 4caj A 2.19 BS01 CA A 1 E285 N287 N288 E292 D304 E94 N96 N97 E101 D113 Q8CJ91 CRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPC 4caj A 2.19 BS02 SIA A 1 N287 N288 I289 N96 N97 I98 Q8CJ91 CRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPC 4caj B 2.19 BS02 SIA B 1 E285 N287 N288 E292 E95 N97 N98 E102 Q8CJ91 LCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCT 4cnj A 2.70 BS01 FAD A 1 G10 G12 P13 A14 E33 K34 K41 T45 N51 T132 I134 T161 T162 G163 Y167 G171 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 G10 G12 P13 A14 E33 K34 K41 T45 N51 T132 I134 T161 T162 G163 Y167 G171 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4cnj B 2.70 BS01 FAD B 1 G10 G12 P13 A14 E33 K34 N35 K41 T45 I134 T161 T162 G163 Y167 G171 S172 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 A378 G10 G12 P13 A14 E33 K34 N35 K41 T45 I134 T161 T162 G163 Y167 G171 S172 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 A378 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4cnj C 2.70 BS01 FAD C 1 I9 G10 G12 P13 A14 E33 K34 N35 K41 T45 G46 T132 I134 T161 T162 G163 Y167 G171 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 I9 G10 G12 P13 A14 E33 K34 N35 K41 T45 G46 T132 I134 T161 T162 G163 Y167 G171 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4cnj D 2.70 BS01 FAD D 1 G10 G12 P13 A14 L32 E33 K34 N35 K41 T45 I134 T162 G163 Y167 G171 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 G10 G12 P13 A14 L32 E33 K34 N35 K41 T45 I134 T162 G163 Y167 G171 F175 F333 G361 E362 T370 G371 G372 F373 N374 I375 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4cnk A 2.00 BS02 MEU A 1 G46 G236 T370 G46 G236 T370 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4cnk B 2.00 BS02 MEU B 1 G46 G236 L240 G46 G236 L240 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4cnk B 2.00 BS03 MEU B 2 G46 G47 R49 R102 G46 G47 R49 R102 1.1.3.2 B1PUC6 25269103 MNHFDTIIIGGGPAGMMATISSSFYGQKTLLLEKNKRLGKKLAGTGGGRCNVTNNGNLDDLMAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGRVFPVTDKSRTIIEALEKKIAELGGTVITNTEIVSVKKTDELFTVRSSDQAWTCQKLIVTTGGKSYPSTGSTGFGHDIARHFKHTVTDLEAAESPLLTDFPHKALQGISLDDVTLSYGKHIITHDLLFTHFGLSGPAALRLSSFVKGGETIYLDVLPQMSQQDLADFLEEHREKSLKNCLKILLPERIADFFTQPFPEKVKQLNLSEKEALIKQIKELPISVTGKMSLAKSFVTKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLHYD 4coq A 1.55 BS02 SAN A 1 H112 H114 H131 V133 V143 L197 T198 T199 W208 H90 H92 H109 V111 V121 L175 T176 T177 W186 4.2.1.1 E8T502 25286845 GAHWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVKACLAPVSVYYVSDAKYVVNNGHTIKVVMGGRGYVVVDGKRFYLKQFHFHAPSEHTVNGKHYPFEAHFVHLDKNGNITVLGVFFKVGKENPELEKVWRVMPEEPGQKRHLTARIDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNNRPVQPLNARKVMK 4coq B 1.55 BS02 SAN B 1 H112 H131 V133 V143 L197 T198 T199 W208 H91 H110 V112 V122 L176 T177 T178 W187 4.2.1.1 E8T502 25286845 GGAHWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVKACLAPVSVYYVSDAKYVVNNGHTIKVVMGGRGYVVVDGKRFYLKQFHFHAPSEHTVNGKHYPFEAHFVHLDKNGNITVLGVFFKVGKENPELEKVWRVMPEEPGQKRHLTARIDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNNRPVQPLNARKVMK 4cta A 2.21 BS01 ATP A 1 L13 T18 L19 D20 T21 N22 G68 G69 L70 G71 D76 P151 G152 P153 E156 L13 T18 L19 D20 T21 N22 G68 G69 L70 G71 D76 P151 G152 P153 E156 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEEEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4cta A 2.21 BS02 ATP B 1 P210 K211 P210 K211 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEEEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4d1n A 2.03 BS02 HEM A 1 W414 C420 V421 G422 M575 F589 S590 G591 W592 E597 W683 F709 Y711 W113 C119 V120 G121 M274 F288 S289 G290 W291 E296 W382 F408 Y410 P29475 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d1n B 2.03 BS04 HEM B 1 W414 R419 C420 V421 G422 S462 M575 F589 S590 G591 W592 M594 E597 W683 F709 Y711 W104 R109 C110 V111 G112 S152 M265 F279 S280 G281 W282 M284 E287 W373 F399 Y401 P29475 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d1n C 2.03 BS02 HEM C 1 W414 A417 C420 V421 G422 S462 F589 S590 G591 W592 M594 E597 W683 F709 Y711 W113 A116 C119 V120 G121 S161 F288 S289 G290 W291 M293 E296 W382 F408 Y410 P29475 CPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVATKDQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4d1o B 1.82 BS01 ARG B 1 Q247 R250 Y331 V336 W356 Y357 E361 N366 Q169 R172 Y253 V258 W278 Y279 E283 N288 1.14.13.39 P29474 KFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 4d1p A 1.73 BS03 Q16 A 1 F105 V336 F353 W356 E361 W447 F38 V257 F274 W277 E282 W368 1.14.13.39 P29474 FPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 4d1p B 1.73 BS03 HEM B 1 W178 A181 C184 V185 S226 F353 S354 G355 W356 M358 E361 W447 F473 Y475 W100 A103 C106 V107 S148 F275 S276 G277 W278 M280 E283 W369 F395 Y397 1.14.13.39 P29474 KFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 4d1p B 1.73 BS05 Q16 B 1 F105 P334 V336 F353 W356 E361 F39 P256 V258 F275 W278 E283 1.14.13.39 P29474 KFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPAPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW 4d2t A 2.70 BS01 3I7 A 1 I17 A23 V25 L27 A38 K40 E57 C70 E87 Y88 C89 P90 I149 D150 I17 A23 V25 L27 A38 K40 E54 C67 E84 Y85 C86 P87 I146 D147 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCACCGALAYAAPELIQGKSGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2t B 2.70 BS01 3I7 B 1 I17 L27 A38 C70 E87 Y88 C89 P90 E93 I149 I18 L27 A38 C70 E87 Y88 C89 P90 E93 I149 2.7.11.1,2.7.10.2 Q14680 HMKDYDELLKYYELHETIGTGGAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2t C 2.70 BS01 3I7 C 1 I17 A38 K40 C70 L86 E87 Y88 C89 P90 E93 I149 I17 A38 K40 C66 L82 E83 Y84 C85 P86 E89 I145 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2t D 2.70 BS01 3I7 D 1 I17 L27 A38 C70 L86 E87 Y88 C89 P90 G92 L139 I149 I15 L25 A36 C68 L84 E85 Y86 C87 P88 G90 L137 I147 2.7.11.1,2.7.10.2 Q14680 DYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2v A 2.45 BS01 45R A 1 I17 V25 L27 A38 C70 L86 E87 Y88 C89 P90 I149 I18 V26 L28 A39 C68 L84 E85 Y86 C87 P88 I147 2.7.11.1,2.7.10.2 Q14680 HMKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCGALAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2v B 2.45 BS01 45R B 1 I17 L27 A38 K40 E57 C70 L86 E87 Y88 C89 P90 I149 D150 I16 L26 A37 K39 E56 C69 L85 E86 Y87 C88 P89 I148 D149 2.7.11.1,2.7.10.2 Q14680 KDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2v B 2.45 BS02 45R C 1 G18 T19 G17 T18 2.7.11.1,2.7.10.2 Q14680 KDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDCGALAYAAPELIQGGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 4d2v D 2.45 BS01 45R D 1 I17 V25 L27 A38 K40 E57 C70 L86 E87 Y88 C89 P90 I149 D150 I15 V23 L25 A36 K38 E55 C68 L84 E85 Y86 C87 P88 I147 D148 2.7.11.1,2.7.10.2 Q14680 DYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKGALAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDTAAALVAKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKFIHLDDDCVTELSVHHRNNRQTMISLWQYDHLTATYLLLLAKKARGKPVRLR 4da2 A 1.80 BS01 CA A 1 D117 E130 T131 D118 E131 T132 Q8U1K8 AMKLMEVSPLFPCIFLRRVNRFVGLVRIKERIERALITNTGRLNEFMIPGRIGYCTPKAGGKTRYILLGFEDHGKIAIIDTRLQGKAFEKIIEKELLPELEGCRIIKREPRVGESRLDYLIECSKGEIFVETKSAVLREGEYAMYPDCPSVRGQRHIKELIKLARDGKRAMIVFIGALPNVSKFKPYKKGDPKIAELLKEALEAGVEIRALGLHMELSGEIIYRGELGVEI 4da2 A 1.80 BS02 CA A 2 E108 D117 E109 D118 Q8U1K8 AMKLMEVSPLFPCIFLRRVNRFVGLVRIKERIERALITNTGRLNEFMIPGRIGYCTPKAGGKTRYILLGFEDHGKIAIIDTRLQGKAFEKIIEKELLPELEGCRIIKREPRVGESRLDYLIECSKGEIFVETKSAVLREGEYAMYPDCPSVRGQRHIKELIKLARDGKRAMIVFIGALPNVSKFKPYKKGDPKIAELLKEALEAGVEIRALGLHMELSGEIIYRGELGVEI 4da2 B 1.80 BS02 CA B 2 E108 D117 R151 E109 D118 R152 Q8U1K8 AMKLMEVSPLFPCIFLRRVNRFVGLVRIKERIERALITNTGRLNEFMIPGRIGYCTPKAGGKTRYILLGFEDHGKIAIIDTRLQGKAFEKIIEKELLPELEGCRIIKREPRVGESRLDYLIECSKGEIFVETKSAVLREGEYAMYPDCPSVRGQRHIKELIKLARDGKRAMIVFIGALPNVSKFKPYKKGDPKIAELLKEALEAGVEIRALGLHMELSGEIIYRGELGVEI 4knr A 2.10 BS01 1S8 A 1 L11 A12 A13 G14 V26 T82 Y103 D105 V131 Y139 N169 T170 G171 V223 E224 G225 L8 A9 A10 G11 V23 T79 Y100 D102 V128 Y136 N166 T167 G168 V220 E221 G222 2.7.7.23,2.3.1.157 P43889 25262942 KALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPI 4knx A 1.90 BS01 1S9 A 1 L11 A12 A13 G14 V26 Q76 Q79 T82 A85 Y103 D105 V131 Y139 N169 T170 V223 E224 G225 L8 A9 A10 G11 V23 Q73 Q76 T79 A82 Y100 D102 V128 Y136 N166 T167 V220 E221 G222 2.7.7.23,2.3.1.157 P43889 25262942 KALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPI 4kpx A 2.21 BS01 1SE A 1 L11 A12 A13 G14 V26 Y103 D105 V131 Y139 N169 T170 V223 G225 L8 A9 A10 G11 V23 Y100 D102 V128 Y136 N166 T167 V220 G222 2.7.7.23,2.3.1.157 P43889 25262942 KALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPI 4kpz A 2.09 BS01 1SF A 1 L11 A12 A13 G14 V26 Q76 Q79 L80 G81 T82 A85 Y103 D105 L8 A9 A10 G11 V23 Q73 Q76 L77 G78 T79 A82 Y100 D102 2.7.7.23,2.3.1.157 P43889 25262942 KALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPI 4kql A 2.31 BS01 1SG A 1 L11 A12 A13 G14 K25 V26 Q76 Q79 L80 G81 T82 A85 Y103 D105 V131 Y139 N169 T170 V223 E224 G225 L8 A9 A10 G11 K22 V23 Q73 Q76 L77 G78 T79 A82 Y100 D102 V128 Y136 N166 T167 V220 E221 G222 2.7.7.23,2.3.1.157 P43889 25262942 KALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPI 4ktx A 2.59 BS01 III B 1 V70 Q162 F163 E164 C165 F194 T215 H223 E224 H227 L256 E262 R363 Y366 N368 D370 V73 Q165 F166 E167 C168 F197 T218 H226 E227 H230 L259 E265 R366 Y369 N371 D373 3.4.24.69 A5HZZ9 GSHMPFVNKQFNYKDPVNGVDIAYIKIPNAGQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLNPPPEAKQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTELKVIDTNSINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHEVLNLTRNGYGSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAGHRLYGIAINPNRVFKVNTNAYYEMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDIASTLNKAKSIVGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVKFFKVLNRKTYLNFDKAVFKINIVPKVNYTIYDGFNLRNTNLAANFNGQNTEINNMNFTKLKNFTGLFEF 4ltu A 2.31 BS01 FES A 1 M24 A37 C39 G41 A43 V44 C45 C48 C86 M24 A37 C39 G41 A43 V44 C45 C48 C86 Q2IU01 PSITFIHPDGRSEIVDAAIGDSAMFAALNHGIDSIVAECGGNAVCATCHVYVDDLWLAKLPPVDANEDDLLDGTASDRLPNSRLSCQIKIAPELDGLVLRIPERQT 4mmo A 2.34 BS01 ZN A 1 H71 D104 E137 E163 H71 D104 E137 E163 Q97V97 MDEELYTLIEFLKKPSISATGEGIDETANYLKETVEKLLGVKANLEKTKGHPVVYAEINVNAKKTLLIYNHYDVQPVDPISEWKRAPFSATIENDRIYARGASDNKGTLMARLFAIKHLLDKNELNVNVKLLYEGEEEIGSVNLEDYIEKNTNKLKADSVIMEGAGLDPKGRPQIVLGVKGLLYVELVLDYGTKDLHSSNAPLVRNPCIDLAKIISTLVDMGGRVLIEGFYDDVRELTEEERELIKKYDIDVEELKKALGFKELKYNEKEKIAEALLTYPTCNVDGFECGYTGKGSKTIVPHRAFAKLDFRLVPNQDPYKVFELLKKHLQKAGFNGEILAHGFEYPVRTSVNSTVVKAMIESAKKVYGTEPQVIPNSAGTQPMGLFVYKLGIRDAVSAIGAGGYYSNAHAPNENIKIDDYYKAIKHTEEFLKLYPIL 4mq4 A 2.20 BS01 2D5 A 1 Y27 Y35 N39 Y40 R44 V53 K57 G81 D101 F102 L103 N106 I157 D158 V159 H160 F182 C183 A186 V187 E219 Y222 M258 D267 Y11 Y19 N23 Y24 R28 V37 K41 G65 D85 F86 L87 N90 I141 D142 V143 H144 F166 C167 A170 V171 E203 Y206 M242 D251 2.1.1.28 P11086 APGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKV 4mq4 B 2.20 BS01 2D5 B 1 Y27 Y35 N39 Y40 R44 V53 K57 G79 G81 D101 F102 L103 N106 D158 V159 H160 F182 C183 A186 V187 A216 E219 Y222 D267 V269 Y2 Y10 N14 Y15 R19 V28 K32 G54 G56 D76 F77 L78 N81 D133 V134 H135 F157 C158 A161 V162 A191 E194 Y197 D242 V244 2.1.1.28 P11086 AYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKV 4mxc A 1.63 BS01 DWF A 1 I1084 V1092 A1108 K1110 E1127 M1131 F1134 L1140 L1157 P1158 Y1159 M1160 G1163 D1164 N1167 L1195 F1200 M1211 V1220 A1221 D1222 F1223 Y1230 I33 V41 A57 K59 E76 M80 F83 L89 L106 P107 Y108 M109 G112 D113 N116 L144 F149 M160 V169 A170 D171 F172 Y179 2.7.10.1 P08581 HIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIG 4mxh A 1.85 BS01 3P7 A 1 S62 K65 Y97 S123 N125 E159 N163 T209 K227 T228 G229 S230 C231 S42 K45 Y77 S103 N105 E139 N143 T189 K207 T208 G209 S210 C211 3.5.2.6 Q3SAW3 DFEHAISDLEAHNQAKIGVALVSENGNLIQGYRANERFAMCSTFKLPLAALVLSRIDAGEENPERKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSALQLSDNAAANLLLKEVGGPPLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKGQLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNAPELQGEERALLIASVAKLARQYVVH 4mxh B 1.85 BS01 MOX B 1 C61 S62 K65 Y97 S123 N125 K227 T228 G229 S230 C41 S42 K45 Y77 S103 N105 K196 T197 G198 S199 3.5.2.6 Q3SAW3 DFEHAISDLEAHNQAKIGVALVSENGNLIQGYRANERFAMCSTFKLPLAALVLSRIDAGEENPERKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSALQLSDNAAANLLLKEVGGPPLLTKYFRSLGDKVSRLDRIERDTTTPMSMAQTVSKLIFGDTLTYKSKGQLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNAPELQGEERALLIASVAKLARQYV 4my6 B 1.70 BS01 3VH B 1 Y16 W23 K69 N71 A73 F77 Q79 R81 V86 Y17 W24 K70 N72 A74 F78 Q80 R82 V87 Q8N8S7 SMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL 4nrn A 1.80 BS01 ZN A 1 H47 E58 H60 H47 E58 H60 O25552 24677509 MLTIETSKKFDKDLKILVKNGFDLKLLYKVVGNLATEQPLAPKYKDHPLKGGLKDFRECHLKPDLLLVYQIKKQENTLFLVRLGSHSELF 4nrn A 1.80 BS02 ZN A 2 E58 H86 E58 H86 O25552 24677509 MLTIETSKKFDKDLKILVKNGFDLKLLYKVVGNLATEQPLAPKYKDHPLKGGLKDFRECHLKPDLLLVYQIKKQENTLFLVRLGSHSELF 4nrt A 2.02 BS01 2NG A 1 F28 W417 T418 R419 H433 R436 Q439 N505 F23 W412 T413 R414 H428 R431 Q434 N500 A0ZNP5 24622391 GTYCGAPILGPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFTQACASLDKTTSSGHPHHMRKNDCWNGESFTGKLADQASKANLMFEGGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDLATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPSFVN 4nru A 2.30 BS01 2NG A 1 F29 L169 M219 M221 L391 R392 R393 Q414 W417 T418 K419 R436 Q439 F27 L167 M217 M219 L389 R390 R391 Q412 W415 T416 K417 R432 Q435 S4V9Y7 24622391 PRPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADKEEGPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGHRPSQLMALLGEAAMHGEKYYRTVASRVSKEAVVPRHRSVLRWVRFG 4nru E 2.30 BS02 2NG E 2 P79 E81 R326 V327 D328 R364 P76 E78 R323 V324 D325 R361 S4V9Y7 24622391 RPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADKEEGPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGHQRPSQLMALLGEAAMHGEKYYRTVASRVSKEAVVPRHRSVLRWVRFG 4nru F 2.30 BS01 2NG F 1 F29 L169 M219 Y341 L391 R392 Q414 W417 T418 K419 Q439 F26 L166 M216 Y338 L388 R389 Q411 W414 T415 K416 Q432 S4V9Y7 24622391 RPSGTYAGLPIADYGDAPPLSTKTMFWRTSPEKLPPGAWEPAYLGSKDERVDGPSLQQVMRDQLKPYSEPRGLLPPQEILDAVCDAIENRLENTLEPQKPWTFKKACESLDKNTSSGYPYHKQKSKDWTGSAFIGDLGDQATHANNMYEMGKSMRPIYTAALKDELVKPDKIYGKIKKRLLWGSDLGTMIRAARAFGPFCDALKETCIFNPIRVGMSMNEDGPFIFARHANFRYHMDADYTRWDSTQQRAILKRAGDIMVRLSPEPDLARVVMDDLLAPSLLDVGDYKIVVEEGLPSGCPCTTQLNSLAHWILTLCAMVEVTRVDPDIVMQESEFSFYGDDEVVSTNLELDMVKYTMALRRYGLLPTRADKEEGPLERRQTLQGISFLRRAIVGDQFGWYGRLDRASIDRQLLWTKGPNHQNPFETLPGPSQLMALLGEAAMHGEKYYRTVASRVSKEVVPRHRSVLRWVRFG 4nsh A 2.10 BS01 QPT A 1 R14 H15 S86 D87 I88 R14 H15 S86 D87 I88 3.2.1.17 P00698 25195881 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4nsi A 2.30 BS02 QPT A 2 R14 H15 T89 N93 K96 R14 H15 T89 N93 K96 3.2.1.17 P00698 25195881 KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL 4ntt A 3.50 BS01 ADP A 1 G52 S53 A70 E121 Y122 V123 T183 D184 G43 S44 A61 E112 Y113 V114 T174 D175 2.7.11.11 P05132 25077557 SEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 4ntt B 3.50 BS01 ADP B 1 S53 V57 A70 E121 V123 L173 T183 D184 S44 V48 A61 E112 V114 L164 T174 D175 2.7.11.11 P05132 25077557 SEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 4nw7 A 2.15 BS02 2O5 A 1 S454 M519 N567 P568 Y575 I582 F586 M603 S614 Q615 F618 L674 F678 S133 M198 N246 P247 Y254 I261 F265 M282 S293 Q294 F297 L338 F342 3.1.4.17 Q07343 24998378 HMSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQLMEKFQF 4p7m A 3.02 BS01 2OE A 1 P1 Y37 M39 S64 N106 P1 Y37 M39 S64 N96 Q6Q3H7 25268646 PCCEVITNVNLPDDNVQSTLSQIENAISDVMGKPLGYIMSNYDYQKNLRFGGSNEAYCFVRITSSNNSALADQITKLLVSNLNVKSRRIYVEFRDNFAFSGSLF 4p7m C 3.02 BS01 2OE A 1 F50 F59 Y96 F46 F55 Y87 Q6Q3H7 25268646 PCCEVITNVNLPDDNVQSTLSQIENAIDVMLGYIMSNYDYQKNLRFGGSNEAYCFVRITSINNNSALADQITKLLVSNLNVKSRRIYVEFRDA 4p7s A 2.87 BS01 2OK B 1 F50 Y57 E98 F99 R100 F50 Y57 E92 F93 R94 Q6Q3H7 25268646 PCCEVITNVNLPDDNVQSTLSQIENAISDVMGKPLGYIMSNYDYQKNLRFGGSNEAYCFVRITSSNNSALADQITKLLVSNLNVKSRRIYVEFRDNFAFSGSLF 4p7s B 2.87 BS01 2OK B 1 P1 Y37 M39 N106 F107 P1 Y35 M37 N95 F96 Q6Q3H7 25268646 PCCEVITNVNLPDDNVQSTLSQIENAISDVKPLGYIMSNYDYQKNLRFGGSNEAYCFVRITSINNSALADQITKLLVSNLNVKSRRIYVEFRDCNFAFGS 4p7s B 2.87 BS02 2OK C 1 F50 Y57 F48 Y55 Q6Q3H7 25268646 PCCEVITNVNLPDDNVQSTLSQIENAISDVKPLGYIMSNYDYQKNLRFGGSNEAYCFVRITSINNSALADQITKLLVSNLNVKSRRIYVEFRDCNFAFGS 4p7s C 2.87 BS01 2OK C 1 P1 M39 S64 A108 P1 M35 S60 A93 Q6Q3H7 25268646 PCCEVITNVNLPDDNVQSTLSQIENAIDVMLGYIMSNYDYQKNLRFGGSNEAYCFVRITSINNNSALADQITKLLVSNLNVKSRRIYVEFRDA 4pdz A 1.73 BS03 CTI B 1 V7 V8 I11 V8 V9 I12 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFE 4pdz B 1.73 BS01 CTI B 1 F43 C84 F43 C84 P02638 25268459 SELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFE 4pe1 A 1.58 BS01 DCD A 1 F43 C84 F87 F44 C85 F88 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFF 4pe1 A 1.58 BS04 DCD B 1 V8 I11 V9 I12 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFF 4pe1 B 1.58 BS02 CA B 1 S18 E21 D23 K24 K26 E31 S19 E22 D24 K25 K27 E32 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFE 4pe4 X 2.18 BS01 REV X 1 F43 L44 I80 A83 C84 F87 F88 F44 L45 I81 A84 C85 F88 F89 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFE 4pe4 A 2.18 BS01 REV X 1 V7 V8 V8 V9 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFE 4pe7 A 1.65 BS04 CA A 3 D63 D69 D64 D70 P02638 25268459 MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFEHE 4pml C 1.87 BS01 3AB C 1 H1031 G1032 Y1060 F1061 K1067 S1068 Y1071 E1138 H79 G80 Y108 F109 K115 S116 Y119 E186 2.4.2.30 Q9H2K2 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pnl D 1.50 BS02 DRL D 1 H1031 G1032 Y1060 K1067 S1068 Y1071 E1138 H67 G68 Y96 K103 S104 Y107 E172 2.4.2.30 Q9H2K2 FQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSGLALAEYVIYRGEQAYPEYLITYQIMRP 4pnm A 2.19 BS02 NU1 A 1 H1031 G1032 Y1060 F1061 A1062 K1067 S1068 Y1071 H70 G71 Y99 F100 A101 K106 S107 Y110 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pnm C 2.19 BS01 NU1 C 1 H1031 G1032 Y1060 A1062 K1067 S1068 Y1071 H81 G82 Y110 A112 K117 S118 Y121 2.4.2.30 Q9H2K2 RENLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pnr A 1.71 BS02 G18 A 1 H1031 G1032 Y1050 Y1060 F1061 A1062 K1067 S1068 Y1071 E1138 H70 G71 Y89 Y99 F100 A101 K106 S107 Y110 E177 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4pns A 1.65 BS02 32Y A 1 H1031 G1032 Y1060 S1068 Y1071 E1138 H70 G71 Y97 S105 Y108 E175 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4pns C 1.65 BS02 32Y C 1 H1031 G1032 Y1060 S1068 Y1071 I1075 E1138 H79 G80 Y108 S116 Y119 I123 E186 2.4.2.30 Q9H2K2 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4q0d E 3.45 BS01 NDP E 1 A11 I19 G20 G23 Q24 L25 G55 R56 K57 T58 I75 S76 S77 S78 R92 C113 G115 E116 S117 T145 A9 I17 G18 G21 Q22 L23 G53 R54 K55 T56 I73 S74 S75 S76 R90 C111 G113 E114 S115 T143 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQEKKLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0d E 3.45 BS03 2XB E 1 S290 I315 N319 D426 L429 G430 F433 Y466 M519 A520 S277 I302 N306 D413 L416 G417 F420 Y453 M506 A507 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQEKKLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0d E 3.45 BS04 MTX E 1 V9 V10 A11 L25 D32 L33 K34 F36 S37 I62 L67 R70 T134 V7 V8 A9 L23 D30 L31 K32 F34 S35 I60 L65 R68 T132 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQEKKLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0d B 3.45 BS01 NDP B 1 V10 A11 I19 G23 Q24 L25 G55 R56 K57 T58 I75 S76 S77 S78 R92 C113 G114 G115 E116 S117 I118 T145 V8 A9 I17 G21 Q22 L23 G53 R54 K55 T56 I73 S74 S75 S76 R90 C111 G112 G113 E114 S115 I116 T143 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQEKKLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0d B 3.45 BS03 2XB B 1 A287 I315 N319 D426 L429 G430 F433 Y466 M519 A520 A274 I302 N306 D413 L416 G417 F420 Y453 M506 A507 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQEKKLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0e A 2.78 BS04 2XB A 2 V9 V10 A11 L25 D32 L33 K34 F36 S37 R70 C113 T134 V7 V8 A9 L23 D30 L31 K32 F34 S35 R68 C111 T132 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0e B 2.78 BS04 2XB B 2 V9 V10 A11 D32 L33 K34 F36 S37 R70 C113 T134 V7 V8 A9 D30 L31 K32 F34 S35 R68 C111 T132 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q0e E 2.78 BS01 NDP E 1 A11 I19 G23 Q24 L25 G55 R56 K57 T58 I75 S76 S77 S78 R92 G114 G115 E116 S117 T145 A9 I17 G21 Q22 L23 G53 R54 K55 T56 I73 S74 S75 S76 R90 G112 G113 E114 S115 T143 2.1.1.45,1.5.1.3 Q5CGA3 25127103 EKNVSIVVAASVLSSGIGINGQLPWSISEDLKFFSKITNNKCDSNKKNALIMGRKTWDSIGRRPLKNRIIVVISSSLPQDEADPNVVVFRNLEDSIENLMNDDSIENIFVCGGESIYRDALKDNFVDRIYLTRVALEDIEFDTYFPEIPETFLPVYMSQTFCTKNISYDFMIFEKQLKSIDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV 4q9m A 2.06 BS01 2ZW A 1 M49 L52 Q53 A71 F72 I87 M88 P91 Y95 Y98 V99 L102 A125 A129 F143 L145 M33 L36 Q37 A55 F56 I71 M72 P75 Y79 Y82 V83 L86 A109 A113 F127 L129 2.5.1.- Q8DRB3 25287857 TQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRH 4q9m A 2.06 BS02 FPP A 1 M27 D28 G29 N30 G31 R32 R41 H45 M49 L52 A71 R79 I87 F143 M11 D12 G13 N14 G15 R16 R25 H29 M33 L36 A55 R63 I71 F127 2.5.1.- Q8DRB3 25287857 TQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRH 4q9o A 2.20 BS01 2ZW A 1 M49 L52 Q53 A71 F72 I87 M88 P91 F94 Y95 Y98 V99 L102 A125 L126 A129 F143 L145 M43 L46 Q47 A65 F66 I81 M82 P85 F88 Y89 Y92 V93 L96 A119 L120 A123 F137 L139 2.5.1.- Q8DRB3 25287857 GSMAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWPDFDEAALQEAILAYNRRH 4qfx A 2.20 BS05 MG A 1 R206 D309 D311 R94 D191 D193 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4qfx C 2.20 BS01 DTP A 1 V156 F157 I325 R372 H376 V378 V44 F45 I207 R254 H258 V260 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4qg0 B 2.30 BS06 DUT D 1 V156 F157 R372 H376 V43 F44 R253 H257 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4qg0 C 2.30 BS04 DGT C 1 Y155 V156 K377 V378 R451 K455 Y43 V44 K259 V260 R333 K337 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4qpl A 1.90 BS01 V3L A 1 K61 Y107 G109 R110 W114 Y116 I139 Y144 Q153 R161 R163 K175 G179 K32 Y78 G80 R81 W85 Y87 I110 Y115 Q124 R132 R134 K146 G150 6.3.2.- Q9CZW6 SLTVPECAICLQTCVHPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGEYAWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVADLENMVQYRRNEHGRRRKIKRDIIDIPKKGVAGLRL 4qpl A 1.90 BS02 ZN A 1 C36 C39 C56 C59 C7 C10 C27 C30 6.3.2.- Q9CZW6 SLTVPECAICLQTCVHPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGEYAWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVADLENMVQYRRNEHGRRRKIKRDIIDIPKKGVAGLRL 4qpl A 1.90 BS03 ZN A 2 C51 H53 C70 C73 C22 H24 C41 C44 6.3.2.- Q9CZW6 SLTVPECAICLQTCVHPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGEYAWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVADLENMVQYRRNEHGRRRKIKRDIIDIPKKGVAGLRL 4qx6 A 2.46 BS01 NAD A 1 G9 G11 R12 I13 N33 D34 L35 R78 A96 T97 G98 F99 F100 T121 A122 C152 N316 Y320 G7 G9 R10 I11 N31 D32 L33 R76 A94 T95 G96 F97 F98 T118 A119 C149 N313 Y317 1.2.1.12 Q8E3E8 VKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHEGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIA 4qx6 B 2.46 BS01 NAD B 1 N8 G9 G11 R12 I13 N33 D34 L35 E77 R78 A96 T97 G98 F99 F100 T121 A122 C152 N316 Y320 N7 G8 G10 R11 I12 N32 D33 L34 E76 R77 A95 T96 G97 F98 F99 T120 A121 C151 N315 Y319 1.2.1.12 Q8E3E8 VVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPANIDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTSQLVRTLEYFAKIAK 4r17 I 2.10 BS02 MG I 2 R27 A178 D204 R27 A178 D204 3.4.25.1 P25451 25244435 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4r17 K 2.10 BS01 3K4 K 1 T2 D17 K33 G130 S131 G132 Y170 S171 T1 D16 K32 G129 S130 G131 Y169 S170 3.4.25.1 P30656 25244435 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4r18 I 2.40 BS02 MG I 2 R27 A178 W182 D204 R27 A178 W182 D204 3.4.25.1 P25451 25244435 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLKMRQD 4r18 K 2.40 BS01 ABA K 1 T2 D17 K33 M45 G130 S131 Y170 S171 T1 D16 K32 M44 G129 S130 Y169 S170 3.4.25.1 P30656 25244435 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4r18 K 2.40 BS03 MG K 2 I82 N85 I81 N84 3.4.25.1 P30656 25244435 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 4r1x A 2.20 BS02 AMP A 1 A214 E215 P216 N235 S236 F237 G238 M239 T240 D304 I325 R328 I334 N339 A215 E216 P217 N236 S237 F238 G239 M240 T241 D305 I326 R329 I335 N340 Q8AAN6 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEAVRVKDLRDN 4r1x A 2.20 BS03 COD A 1 S136 G137 F141 F147 A163 H182 A214 E215 P216 N235 S236 F237 G238 M239 T240 G244 P245 D304 I325 R328 I334 G337 N339 S137 G138 F142 F148 A164 H183 A215 E216 P217 N236 S237 F238 G239 M240 T241 G245 P246 D305 I326 R329 I335 G338 N340 Q8AAN6 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEAVRVKDLRDN 4r1x B 2.20 BS03 COD B 1 S93 S94 S136 G137 F141 G143 A163 H182 I184 A214 E215 P216 N235 S236 F237 G238 G244 P245 D304 I325 R328 E422 G423 K424 S91 S92 S132 G133 F137 G139 A159 H178 I180 A210 E211 P212 N231 S232 F233 G234 G240 P241 D300 I321 R324 E414 G415 K416 Q8AAN6 TQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLR 4r1x D 2.20 BS03 COD D 1 S136 G137 F141 F147 H182 I184 A214 E215 P216 N235 S236 F237 G238 M239 T240 G244 P245 D304 I325 R328 E422 G423 K424 S130 G131 F135 F141 H176 I178 A208 E209 P210 N229 S230 F231 G232 M233 T234 G238 P239 D298 I319 R322 E414 G415 K416 Q8AAN6 STQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRDN 4r59 A 1.65 BS02 3J3 A 1 L91 H94 H96 H119 V121 V134 L140 L197 T198 T199 W208 L89 H92 H94 H117 V119 V132 L138 L195 T196 T197 W206 4.2.1.1 P00918 25254302 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4r5a A 1.64 BS02 3J4 A 1 W5 N62 H64 Q67 Q92 H94 H96 H119 V143 L198 T199 T200 P201 P202 W209 W5 N62 H64 Q67 Q92 H94 H96 H119 V142 L197 T198 T199 P200 P201 W208 4.2.1.1 P00918 25254302 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4r5b A 1.50 BS02 3J4 A 1 N62 N67 Q92 H94 H96 H119 F131 L198 T199 T200 W209 N62 N67 Q92 H94 H96 H119 F130 L197 T198 T199 W208 4.2.1.1 P00918 25254302 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4ras A 2.30 BS01 SF4 A 1 S472 R473 I474 L479 F511 C512 C515 C518 C568 P569 W570 S472 R473 I474 L479 F511 C512 C515 C518 C568 P569 W570 K2MB66 MRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSAG 4ras A 2.30 BS02 SF4 A 2 C522 P523 C524 I527 C548 Y551 C561 R563 C564 C522 P523 C524 I527 C548 Y551 C561 R563 C564 K2MB66 MRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSAG 4ras A 2.30 BS03 B12 A 1 V276 D289 F290 F291 Y379 Q403 S422 Y426 V457 I458 H459 N460 P461 I463 V471 I474 D476 T477 L478 S487 K488 S489 F535 Y538 I540 K542 A543 V545 C548 T549 R552 C561 G562 M565 V276 D289 F290 F291 Y379 Q403 S422 Y426 V457 I458 H459 N460 P461 I463 V471 I474 D476 T477 L478 S487 K488 S489 F535 Y538 I540 K542 A543 V545 C548 T549 R552 C561 G562 M565 K2MB66 MRLYSNRDRPNHLGPLALERLARVDDVVAQPARQPEDGFAASEDSLLGDVEEYARLFTRFLDGPVAPLGDAIPDDPARRAENLKASAYFLDASMVGICRLDPDDRAGDCDPSHTHALVFAVQFGREPEAGEAGAEWIRGTNAARTDMRCAEIAAILSGYVRWMGFPARGHFSGDAQVDLARLAVRAGLARVVDGVLVAPFLRRGFRLGVVTTGYALAADRPLAPEGDLGETAPEVMLGIDGTRPGWEDAEEEKRPLHMGRYPMETIRRVDEPTTLVVRQEIQRVAKRGDFFKRAEAGDLGEKAKQEKKRFPMKHPLALGMQPLIQNMVPLQGTREKLAPTGKGGDLSDPGRNAEAIKALGYYLGADFVGICRAEPWMYYASDEVEGKPIEAYHDYAVVMLIDQGYETMEGASGDDWISASQSMRAYMRGAEIAGVMAAHCRRMGYSARSHSNAHSEVIHNPAILMAGLGEVSRIGDTLLNPFIGPRSKSIVFTTDLPMSVDRPIDFGLQDFCNQCRKCARECPCNAISFGDKVMFNGYEIWKADVEKCTKYRVTQMKGSACGRCMKMCPWNREDTVEGRRLAELSIKVPEARAAIIAMDDALQNGKRNLIKRWWFDLEVIDGVAGAPRMGTNERDLSPDRGDKIGANQKLAMYPPRLQPPPGTTLDAVLPVDRSGGLAEYAAAETPAAARARLKSSAG 4rb5 B 2.40 BS01 NUC A 1 W24 P26 R96 G99 G100 T103 N104 T107 I108 R111 K133 R144 Y148 I172 E176 K179 W18 P20 R90 G93 G94 T97 N98 T101 I102 R105 K127 R138 Y142 I166 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rb5 B 2.40 BS02 MG B 1 E84 Q212 P234 E78 Q206 P228 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rb5 C 2.40 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 R127 S154 G155 R156 E161 Q162 A163 W167 R172 V173 P174 L175 H176 T177 L178 R179 F186 L188 T192 Y193 G194 V195 L196 G197 K199 G1 N2 K3 I4 F9 K25 R126 S153 G154 R155 E160 Q161 A162 W166 R171 V172 P173 L174 H175 T176 L177 R178 F185 L187 T191 Y192 G193 V194 L195 G196 K198 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4rb5 D 2.40 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 R49 S52 Y54 A55 R57 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 S113 R115 Q116 Q119 R122 H123 H125 R132 V133 D134 L135 S137 R141 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 R48 S51 Y53 A54 R56 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 S112 R114 Q115 Q118 R121 H122 H124 R131 V132 D133 L134 S136 R140 L154 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4rb5 E 2.40 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y61 R64 F84 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y57 R60 F80 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rb5 E 2.40 BS02 MG E 1 E68 P70 R143 D147 E64 P66 R139 D143 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rb5 E 2.40 BS03 MG E 2 G85 S87 N130 G81 S83 N126 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rb5 G 2.40 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 R94 R95 S98 R102 N109 R114 R115 A116 R119 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 R93 R94 S97 R101 N108 R113 R114 A115 R118 P17291 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4rb5 H 2.40 BS01 NUC A 1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K32 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 R105 S113 T114 S115 G128 V129 G130 E132 L1 T2 D3 P4 A6 D7 T10 R11 R13 N14 R17 V18 K20 S28 R29 F30 K31 K55 R74 K87 P88 G89 R90 R91 Y93 V94 G95 V96 R104 S112 T113 S114 G127 V128 G129 E131 Q5SHQ2 LTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4rb5 I 2.40 BS01 NUC A 1 Q3 Y5 T7 R9 K11 E12 V14 R16 F18 R20 Y36 Q38 G39 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 K116 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 K10 E11 V13 R15 F17 R19 Y35 Q37 G38 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 K115 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4rb5 J 2.40 BS01 NUC A 1 R5 K7 R9 H13 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 T48 I50 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 D73 R2 K4 R6 H10 D14 S32 G33 P34 I35 P36 L37 P38 T39 R40 V41 R42 T45 I47 R48 G49 P50 F51 K52 H53 K54 S56 R57 H59 H65 R67 D70 Q5SHN7 IRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4rb5 K 2.40 BS01 NUC A 1 Y20 N26 N27 I29 T31 D36 G37 N38 P39 W42 S44 G46 V47 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 Y8 N14 N15 I17 T19 D24 G25 N26 P27 W30 S32 G34 V35 G40 S41 K43 R73 P101 V102 P103 H104 N105 G106 C107 R108 P109 K110 K111 P80376 QVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4rb5 L 2.40 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K23 L27 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 T61 Y69 P71 G72 E73 G74 R86 G87 R89 V90 K91 D92 P94 G95 R97 V104 R113 K114 K115 S116 R117 S118 K119 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K19 L23 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 P67 G68 E69 G70 R82 G83 R85 V86 K87 D88 P90 G91 R93 V100 R109 K110 K111 S112 R113 S114 K115 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPK 4rb5 M 2.40 BS01 NUC A 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 L70 N77 I78 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 K111 P113 R114 K115 T116 V117 K12 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 L69 N76 I77 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 K110 P112 R113 K114 T115 V116 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAP 4rb5 N 2.40 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 F16 K17 V18 R19 Y21 T22 R23 C27 R29 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 F15 K16 V17 R18 Y20 T21 R22 C26 R28 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4rb5 O 2.40 BS01 NUC A 1 P2 K5 K8 Q9 I12 F18 D21 T22 G23 S24 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 G61 Q62 R64 R65 R68 Y69 P1 K4 K7 Q8 I11 F17 D20 T21 G22 S23 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 G60 Q61 R63 R64 R67 Y68 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4rb5 P 2.40 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 K31 Y32 I33 Y38 P41 R42 K43 T44 T45 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 K31 Y32 I33 Y38 P41 R42 K43 T44 T45 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQ 4rb5 Q 2.40 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 R92 N94 Y95 S97 L98 K100 P1 K2 K3 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 R91 N93 Y94 S96 L97 K99 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4rb5 T 2.40 BS01 NUC A 1 L10 S11 A12 K14 R15 H16 R17 Q18 S19 R22 R23 N26 A28 K29 S31 A32 K34 T35 L36 K38 K39 L43 E51 K54 I55 R57 E60 S61 D64 K68 S70 H73 N75 A78 R79 K81 S82 R83 M85 R86 R89 G101 G102 G103 L3 S4 A5 K7 R8 H9 R10 Q11 S12 R15 R16 N19 A21 K22 S24 A25 K27 T28 L29 K31 K32 L36 E44 K47 I48 R50 E53 S54 D57 K61 S63 H66 N68 A71 R72 K74 S75 R76 M78 R79 R82 G94 G95 G96 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGG 4rb6 D 2.40 BS01 NUC A 1 K7 P8 Y9 T10 P11 S12 R13 R14 F15 F21 E28 K31 K35 P36 L37 K38 K39 T40 G41 G42 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 R54 G55 G56 H58 K59 R60 L61 Y62 R63 K68 K78 Y84 P86 N87 R88 D99 G100 E101 K102 L147 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 L177 P178 S179 E181 R183 A199 H201 K202 V205 L206 G207 K208 A209 G210 R211 S212 R213 W214 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 H233 G236 E237 G238 R239 A240 P241 R242 G243 R244 P246 A247 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 K261 R263 K264 P265 S266 R268 F269 I270 R273 R274 K6 P7 Y8 T9 P10 S11 R12 R13 F14 F20 E27 K30 K34 P35 L36 K37 K38 T39 G40 G41 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 R53 G54 G55 H57 K58 R59 L60 Y61 R62 K67 K77 Y83 P85 N86 R87 D98 G99 E100 K101 L146 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 L176 P177 S178 E180 R182 A198 H200 K201 V204 L205 G206 K207 A208 G209 R210 S211 R212 W213 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 H232 G235 E236 G237 R238 A239 P240 R241 G242 R243 P245 A246 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 K260 R262 K263 P264 S265 R267 F268 I269 R272 R273 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rb6 D 2.40 BS11 MG D 10 L147 E148 Y172 H186 L146 E147 Y171 H185 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rb6 D 2.40 BS12 MG D 11 A224 A225 M226 A223 A224 M225 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rb6 E 2.40 BS01 NUC A 1 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 Q48 Q54 K57 R58 N60 R61 P62 L63 G65 H66 K69 R76 L78 R79 E80 R82 R101 S108 K109 G110 R111 G112 F113 G115 M117 K118 R119 N121 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 G153 K154 M156 A157 H159 Y160 R164 V165 T166 M168 N169 K185 G186 A187 V188 P189 G190 P191 N192 K202 K203 A204 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 Q48 Q54 K57 R58 N60 R61 P62 L63 G65 H66 K69 R76 L78 R79 E80 R82 R101 S108 K109 G110 R111 G112 F113 G115 M117 K118 R119 N121 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 G153 K154 M156 A157 H159 Y160 R164 V165 T166 M168 N169 K185 G186 A187 V188 P189 G190 P191 N192 K202 K203 A204 Q5SHN8 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKA 4rb6 E 2.40 BS06 MG E 5 G106 T107 G194 L195 G106 T107 G194 L195 Q5SHN8 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKA 4rb6 F 2.40 BS01 NUC A 1 N29 H31 L32 W34 E35 R38 W39 Q40 L41 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 P81 I82 F83 V84 G85 V88 V89 F90 G91 P92 P94 R95 Y99 T100 L101 P102 K103 K104 V105 R106 K108 G134 K135 T136 L140 R165 R168 N169 L170 P171 L176 E179 G180 N182 Y184 R205 N24 H26 L27 W29 E30 R33 W34 Q35 L36 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 Q62 K63 H64 G66 R67 A68 R69 H70 G71 P76 I77 F78 V79 G80 V83 V84 F85 G86 P87 P89 R90 Y94 T95 L96 P97 K98 K99 V100 R101 K103 G129 K130 T131 L135 R160 R163 N164 L165 P166 L171 E174 G175 N177 Y179 R200 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4rb6 F 2.40 BS12 MG F 11 R164 T175 R159 T170 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4rb6 F 2.40 BS13 MG F 12 R117 V187 T189 E190 R112 V182 T184 E185 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4rb6 G 2.40 BS01 NUC A 1 K36 V38 N40 G42 L43 E45 K47 T71 A73 K74 K75 I77 N79 F80 L82 I88 S124 F125 D126 R128 N132 L133 G134 L135 R136 G154 M155 D156 A158 V160 K35 V37 N39 G41 L42 E44 K46 T70 A72 K73 K74 I76 N78 F79 L81 I87 S123 F124 D125 R127 N131 L132 G133 L134 R135 G153 M154 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rb6 G 2.40 BS04 MG G 2 L139 F141 P142 I144 L138 F140 P141 I143 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rb6 H 2.40 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 L71 N74 K85 G108 F109 S110 H111 K138 Q139 G142 Q143 R152 Y157 H158 K160 K172 G174 K175 S1 R2 I3 R58 K61 S62 G65 L66 T69 L70 N73 K84 G107 F108 S109 H110 K137 Q138 G141 Q142 R151 Y156 H157 K159 K171 G173 K174 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRLKPGK 4rb6 I 2.40 BS02 MG I 1 S91 D96 S91 D96 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4rb6 N 2.40 BS01 NUC A 1 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 T73 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 R115 K118 K121 H130 Q133 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 T73 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 R115 K118 K121 H130 Q133 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rb6 N 2.40 BS02 MG N 1 R35 W42 T43 V46 M48 R35 W42 T43 V46 M48 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rb6 N 2.40 BS04 MG N 3 R25 L26 K29 V140 R25 L26 K29 V140 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rb6 N 2.40 BS06 MG U 1 K2 Y4 K2 Y4 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rb6 O 2.40 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K67 E68 K70 R78 N82 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K67 E68 K70 R78 N82 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rb6 O 2.40 BS02 MG O 1 A46 I47 P48 R49 G50 V52 A46 I47 P48 R49 G50 V52 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rb6 O 2.40 BS03 MG O 2 D12 T14 V85 I86 P93 R94 G95 D12 T14 V85 I86 P93 R94 G95 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rb6 O 2.40 BS04 MG O 3 V10 R17 V10 R17 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rb6 P 2.40 BS01 NUC A 1 L3 S4 R7 P8 N9 P10 G11 A12 N13 K14 R16 K17 R18 V19 G20 R21 G22 P23 G24 S25 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 P48 R49 R50 F51 E52 G53 G54 R55 S56 T58 M60 R61 L62 P63 K64 R65 G66 M67 Q68 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 R90 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 S133 L3 S4 R7 P8 N9 P10 G11 A12 N13 K14 R16 K17 R18 V19 G20 R21 G22 P23 G24 S25 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 P48 R49 R50 F51 E52 G53 G54 R55 S56 T58 M60 R61 L62 P63 K64 R65 G66 M67 Q68 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 R90 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 S133 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLE 4rb6 P 2.40 BS02 MG F 13 M1 K2 M1 K2 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLE 4rb6 P 2.40 BS04 MG P 2 R33 K39 R33 K39 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLE 4rb6 P 2.40 BS06 MG P 4 G26 H27 G28 A31 T32 G26 H27 G28 A31 T32 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLE 4rb6 P 2.40 BS07 MG P 5 G44 L45 G44 L45 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLE 4rb6 Q 2.40 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 K22 G24 Y26 W41 Q45 Q46 A49 R56 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 K22 G24 Y26 W41 Q45 Q46 A49 R56 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rb6 Q 2.40 BS06 MG Q 4 T21 V96 V97 K98 R101 T21 V96 V97 K98 R101 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rb6 R 2.40 BS01 NUC A 1 M1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 R68 Q71 V73 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 M1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 R68 Q71 V73 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4rb6 S 2.40 BS02 NUC B 1 R10 K11 R15 K19 R25 F29 R30 S31 L32 K33 Y36 Q38 I40 G45 V46 T47 S50 L54 N61 K62 T63 Y92 K93 H95 G96 R97 R8 K9 R13 K17 R23 F27 R28 S29 L30 K31 Y34 Q36 I38 G43 V44 T45 S48 L52 N59 K60 T61 Y90 K91 H93 G94 R95 Q5SHQ4 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4rb6 S 2.40 BS03 MG S 1 R15 S27 V28 D88 R89 G90 R13 S25 V26 D86 R87 G88 Q5SHQ4 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4rb6 S 2.40 BS04 MG S 2 I35 K62 A66 R97 I33 K60 A64 R95 Q5SHQ4 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4rb6 T 2.40 BS01 NUC A 1 M1 N2 R3 G4 R23 R51 R53 R54 N55 G56 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 K119 M1 N2 R3 G4 R23 R51 R53 R54 N55 G56 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 K119 P60490 MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDQDRAAERAA 4rb6 T 2.40 BS02 MG T 1 D117 R118 K119 D117 R118 K119 P60490 MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDQDRAAERAA 4rb6 U 2.40 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 V9 R10 R11 R12 K13 H14 K15 K16 K19 K22 G23 Y24 W25 G26 L27 R28 K30 S31 F32 R33 K34 R36 E37 A41 A42 Y45 A46 Y47 H49 R50 K51 R52 R53 K54 R55 F57 R58 R59 W61 I62 V63 N66 R70 N75 Y76 S77 I80 H81 K84 D91 R92 K93 P1 R2 A3 K4 T5 G6 V7 V8 R9 R10 R11 K12 H13 K14 K15 K18 K21 G22 Y23 W24 G25 L26 R27 K29 S30 F31 R32 K33 R35 E36 A40 A41 Y44 A45 Y46 H48 R49 K50 R51 R52 K53 R54 F56 R57 R58 W60 I61 V62 N65 R69 N74 Y75 S76 I79 H80 K83 D90 R91 K92 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rb6 U 2.40 BS03 MG U 3 V9 R12 K13 V8 R11 K12 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rb6 U 2.40 BS04 MG U 1 D97 R101 D96 R100 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rb6 U 2.40 BS08 MG U 7 K5 G7 K4 G6 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rb6 W 2.40 BS01 NUC A 1 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4rb6 W 2.40 BS03 MG W 2 Y75 D77 H102 I103 T104 Y75 D77 H102 I103 T104 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4rb6 X 2.40 BS04 MG X 3 R73 P74 R76 R73 P74 R76 Q5SHP0 MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL 4rb6 X 2.40 BS05 MG X 4 V59 R60 G61 P74 D75 R76 V59 R60 G61 P74 D75 R76 Q5SHP0 MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL 4rb6 X 2.40 BS06 MG X 5 A17 F21 K25 Y26 T27 A17 F21 K25 Y26 T27 Q5SHP0 MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL 4rb6 Y 2.40 BS01 NUC A 1 M1 R2 K4 H6 K8 K9 S17 G18 K19 K21 V30 P32 K34 Y35 K46 K47 A48 V49 R50 V51 G58 G59 F60 H68 S70 K71 R73 R84 R86 K87 K94 K95 M1 R2 K4 H6 K8 K9 S17 G18 K19 K21 V30 P32 K34 Y35 K46 K47 A48 V49 R50 V51 G58 G59 F60 H68 S70 K71 R73 R84 R86 K87 K94 K95 Q5SHP9 MRVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCGGALD 4rb6 Y 2.40 BS03 MG Y 1 I38 V39 V42 N43 A65 L67 I38 V39 V42 N43 A65 L67 Q5SHP9 MRVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCGGALD 4rb6 Z 2.40 BS01 NUC A 1 I146 H151 E169 T170 I129 H134 E152 T153 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVEIHRDILVKVSPRNIPEFIEVDVIGDSLHASDLKLPPGVELAVSPEETI 4rb6 Z 2.40 BS02 NUC B 1 R10 K14 P15 R19 V27 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R10 K14 P15 R19 V27 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVEIHRDILVKVSPRNIPEFIEVDVIGDSLHASDLKLPPGVELAVSPEETI 4rb6 Z 2.40 BS03 MG B 1 Y29 D87 Y29 D87 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVEIHRDILVKVSPRNIPEFIEVDVIGDSLHASDLKLPPGVELAVSPEETI 4rb6 0 2.40 BS01 NUC A 1 A2 H3 K4 G8 T10 N12 R14 D15 S16 Q17 A18 K19 R20 K24 R25 Y26 E27 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 L62 F69 R74 L75 R77 A1 H2 K3 G7 T9 N11 R13 D14 S15 Q16 A17 K18 R19 K23 R24 Y25 E26 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 G53 R54 D55 F56 T57 F59 L61 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4rb6 0 2.40 BS04 MG 0 2 T10 R11 T9 R10 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4rb6 0 2.40 BS06 MG 0 4 E68 H80 E67 H79 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4rb6 1 2.40 BS01 NUC A 1 S2 K3 K10 R11 P12 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 G28 G29 V30 G31 K32 K33 T34 T35 I37 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 R61 A64 S65 H66 K69 R76 G79 L80 K81 K92 S1 K2 K9 R10 P11 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 G27 G28 V29 G30 K31 K32 T33 T34 I36 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 R60 A63 S64 H65 K68 R75 G78 L79 K80 K91 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4rb6 2 2.40 BS03 MG 2 2 K54 I57 K54 I57 Q5SHP6 MKLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQ 4rb6 3 2.40 BS04 MG 3 2 L31 Q32 Q33 L30 Q31 Q32 Q5SHQ6 PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 4rb6 5 2.40 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 D17 A18 R19 R20 S21 H22 H23 A24 T29 V31 P32 P34 K40 P42 H43 Y52 A53 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 D16 A17 R18 R19 S20 H21 H22 A23 T28 V30 P31 P33 K39 P41 H42 Y51 A52 P80339 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4rb6 6 2.40 BS01 NUC A 1 A2 S3 R6 K8 R18 R19 Y21 A22 T23 E24 K25 N26 N29 T30 L36 R37 K38 Y39 W42 R44 K45 H46 I54 A1 S2 R5 K7 R17 R18 Y20 A21 T22 E23 K24 N25 N28 T29 L35 R36 K37 Y38 W41 R43 K44 H45 I53 P35871 ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4rb6 6 2.40 BS03 MG 6 1 E51 V52 K53 E50 V51 K52 P35871 ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4rb6 7 2.40 BS03 MG 7 2 R21 V30 L42 P44 R21 V30 L42 P44 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4rb6 8 2.40 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K11 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 Q35 S37 G38 K39 I41 R42 Q43 K44 R46 K47 F48 V49 L50 A51 K52 P53 E54 R57 Y64 P1 K2 M3 K4 T5 H6 K7 K10 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 Q34 S36 G37 K38 I40 R41 Q42 K43 R45 K46 F47 V48 L49 A50 K51 P52 E53 R56 Y63 Q5SKU1 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 4rb6 8 2.40 BS02 MG 8 1 M4 L60 P63 M3 L59 P62 Q5SKU1 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 4rb6 9 2.40 BS01 NUC A 1 M1 K2 V3 R4 A5 S6 V7 K8 R9 I10 K15 V16 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 K2 V3 R4 A5 S6 V7 K8 R9 I10 K15 V16 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 Q5SHR2 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 4rb7 B 2.40 BS01 NUC A 1 P26 R96 G99 G100 T103 N104 T107 R111 K133 R144 I172 R175 E176 K179 P20 R90 G93 G94 T97 N98 T101 R105 K127 R138 I166 R169 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rb7 D 2.40 BS01 NUC A 1 G2 R3 I5 V8 C9 R10 R13 R14 K22 G23 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 R57 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 S137 Y138 R141 L155 E156 L157 E205 S208 R209 G1 R2 I4 V7 C8 R9 R12 R13 K21 G22 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 R56 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 S136 Y137 R140 L154 E155 L156 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4rb7 E 2.40 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 P49 K57 Y61 F84 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 P45 K53 Y57 F80 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rb7 E 2.40 BS02 MG E 1 E68 P70 L142 R143 D147 E64 P66 L138 R139 D143 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rb7 J 2.40 BS01 NUC A 1 K7 R9 H13 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 L71 K3 R5 H9 D13 S31 G32 P33 I34 P35 L36 P37 T38 R39 V40 R41 R42 T44 R47 G48 P49 F50 K51 H52 K53 S55 R56 H58 H64 R66 L67 Q5SHN7 RIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4rb7 L 2.40 BS03 MG L 1 V66 T67 G95 V96 R97 Y98 V62 T63 G91 V92 R93 Y94 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPK 4rb7 M 2.40 BS01 NUC A 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 K27 A28 R29 R44 L70 V74 N77 I78 Y87 R88 R91 H92 L96 P97 V98 R99 Q101 R102 T103 R104 T105 N106 R108 T109 R110 K111 P113 R114 K115 T116 V117 K120 K11 R12 V15 Y19 I20 Y21 G22 I23 G24 K25 A26 R27 R42 L68 V72 N75 I76 Y85 R86 R89 H90 L94 P95 V96 R97 Q99 R100 T101 R102 T103 N104 R106 T107 R108 K109 P111 R112 K113 T114 V115 K118 P80377 RIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAP 4rb7 M 2.40 BS03 NUC X 1 T116 G119 K121 T114 G117 K119 P80377 RIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAP 4rb7 N 2.40 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 K15 F16 K17 V18 R19 Y21 T22 C27 R29 A30 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 K14 F15 K16 V17 R18 Y20 T21 C26 R28 A29 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4rb7 Q 2.40 BS02 MG Q 1 K50 Y51 K52 D55 K49 Y50 K51 D54 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4rb7 R 2.40 BS02 MG R 1 D30 R32 D33 D11 R13 D14 Q5SLQ0 AKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVR 4rb8 D 2.40 BS03 MG D 2 T27 E28 P29 T26 E27 P28 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rb8 F 2.40 BS07 MG F 6 D96 S98 D91 S93 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4rb8 G 2.40 BS01 NUC A 1 K36 V38 N40 G42 L43 E45 K47 T71 A73 K74 K75 I77 N79 F80 I88 S124 D126 R128 N132 G134 L135 R136 G154 D156 A158 V160 K35 V37 N39 G41 L42 E44 K46 T70 A72 K73 K74 I76 N78 F79 I87 S123 D125 R127 N131 G133 L134 R135 G153 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rb8 I 2.40 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 S42 K45 A46 A49 R50 K22 P23 G24 Y25 N28 Y29 S42 K45 A46 A49 R50 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4rb8 N 2.40 BS01 NUC A 1 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 R35 K37 N45 F51 T63 G64 K66 Q69 K70 T73 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 R97 E100 H101 A102 G105 M106 P108 P111 L112 R114 F117 K118 P129 H130 Q133 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 R35 K37 N45 F51 T63 G64 K66 Q69 K70 T73 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 R97 E100 H101 A102 G105 M106 P108 P111 L112 R114 F117 K118 P129 H130 Q133 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rb8 O 2.40 BS02 MG O 1 A11 F99 A11 F99 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rb8 Q 2.40 BS01 NUC A 1 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 K18 K22 G24 Y26 A28 F29 W41 Q46 A49 R56 K63 R67 F69 D71 Y74 T75 K76 K77 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 K18 K22 G24 Y26 A28 F29 W41 Q46 A49 R56 K63 R67 F69 D71 Y74 T75 K76 K77 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rb8 Q 2.40 BS02 NUC B 1 R16 L17 K18 G19 E38 R16 L17 K18 G19 E38 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rb8 Q 2.40 BS04 MG Q 2 K76 K77 N89 E91 K76 K77 N89 E91 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rb8 S 2.40 BS02 NUC B 1 R10 R15 K19 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 I40 G45 V46 T47 S50 L54 A55 G60 N61 K62 T63 Y92 K93 H95 G96 R97 R8 R13 K17 R23 F27 R28 S29 L30 K31 H32 Y34 Q36 I38 G43 V44 T45 S48 L52 A53 G58 N59 K60 T61 Y90 K91 H93 G94 R95 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4rb8 V 2.40 BS01 NUC A 1 G8 G9 K10 E23 K24 R66 K69 K74 F75 K76 A77 K78 V79 Q80 Y81 R82 R83 K84 K85 G86 H87 Q89 P90 G8 G9 K10 E23 K24 R66 K69 K74 F75 K76 A77 K78 V79 Q80 Y81 R82 R83 K84 K85 G86 H87 Q89 P90 P60492 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4rb8 W 2.40 BS02 MG W 1 N40 K41 N40 K41 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4rb8 Z 2.40 BS01 NUC A 1 K46 I146 G147 E169 T170 K46 I132 G133 E155 T156 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAV 4rb8 Z 2.40 BS03 MG Z 1 M1 H55 V56 M1 H55 V56 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAV 4rb9 B 2.55 BS01 NUC A 1 K22 W24 P26 R96 G99 G100 T103 N104 I108 R111 K133 R144 I172 E176 K179 K16 W18 P20 R90 G93 G94 T97 N98 I102 R105 K127 R138 I166 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rb9 L 2.55 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 V18 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 K57 T61 Y69 G72 E73 G74 R86 G87 R89 V90 K91 D92 P94 G95 R97 V101 V104 Y105 R113 K114 K115 S116 R117 S118 K119 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 V14 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 K53 T57 Y65 G68 E69 G70 R82 G83 R85 V86 K87 D88 P90 G91 R93 V97 V100 Y101 R109 K110 K111 S112 R113 S114 K115 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPK 4rba D 2.55 BS02 MG D 1 A224 A225 M226 G235 A223 A224 M225 G234 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rba G 2.55 BS01 NUC A 1 K36 V38 N40 G42 L43 E45 K47 T71 A73 K74 I77 N79 F80 I88 R91 S124 D126 R128 N132 L133 G134 L135 G154 M155 D156 A158 V160 K35 V37 N39 G41 L42 E44 K46 T70 A72 K73 I76 N78 F79 I87 R90 S123 D125 R127 N131 L132 G133 L134 G153 M154 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rba I 2.55 BS01 NUC A 1 K22 G24 Y25 R27 N28 Y29 R33 S42 N43 A46 A49 R50 A53 K22 G24 Y25 R27 N28 Y29 R33 S42 N43 A46 A49 R50 A53 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4rba N 2.55 BS01 NUC A 1 T3 V5 W13 L23 G24 R25 T28 A31 R35 K37 N45 F51 T63 G64 K65 K66 Q69 K70 T73 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 L107 P108 K109 G110 P111 L112 R114 K118 K121 P129 H130 Q133 T3 V5 W13 L23 G24 R25 T28 A31 R35 K37 N45 F51 T63 G64 K65 K66 Q69 K70 T73 R74 Y75 S76 Y78 P79 G80 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 L107 P108 K109 G110 P111 L112 R114 K118 K121 P129 H130 Q133 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rba Q 2.55 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 K22 G24 Y26 F29 W41 Q45 Q46 A49 V52 R56 R67 F69 D71 Y74 T75 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 K22 G24 Y26 F29 W41 Q45 Q46 A49 V52 R56 R67 F69 D71 Y74 T75 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rba U 2.55 BS06 MG U 5 K5 T6 G7 K4 T5 G6 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rba Z 2.55 BS01 NUC A 1 K46 G114 I120 I146 H151 E169 T170 K46 G114 I120 I146 H151 E169 T170 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETI 4rba 2 2.55 BS01 NUC A 1 M1 K2 L3 S4 R7 L10 R14 K29 S45 Q46 N47 H48 I50 R51 K54 R55 A58 R59 L61 T62 N65 E66 R69 M1 K2 L3 S4 R7 L10 R14 K29 S45 Q46 N47 H48 I50 R51 K54 R55 A58 R59 L61 T62 N65 E66 R69 Q5SHP6 MKLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQ 4rba 5 2.55 BS03 MG 5 1 T11 S12 K13 R16 T10 S11 K12 R15 P80339 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4rba 6 2.55 BS02 MG 6 1 Y21 K38 Y39 H46 Y20 K37 Y38 H45 P35871 ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4rba 7 2.55 BS02 MG 7 1 R21 L42 P44 R21 L42 P44 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4rbb B 2.55 BS01 NUC A 1 K22 W24 P26 R96 G99 G100 T103 N104 T107 R111 K133 R144 I172 R175 E176 K179 K16 W18 P20 R90 G93 G94 T97 N98 T101 R105 K127 R138 I166 R169 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rbb C 2.55 BS01 NUC A 1 G2 N3 K4 I5 F10 I14 K26 R127 S154 G155 R156 E161 A163 W167 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 T192 Y193 G194 V195 L196 G197 K199 G1 N2 K3 I4 F9 I13 K25 R126 S153 G154 R155 E160 A162 W166 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 T191 Y192 G193 V194 L195 G196 K198 P80372 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4rbb D 2.55 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 R57 L58 R59 Q62 R65 R66 E72 R73 Q74 N77 G87 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 S137 Y138 R141 L155 E156 L157 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 R56 L57 R58 Q61 R64 R65 E71 R72 Q73 N76 G86 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 S136 Y137 R140 L154 E155 L156 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4rbb K 2.55 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 D36 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 R85 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 Y8 H10 N14 N15 I17 T19 D24 G25 N26 P27 I28 W30 S32 G34 V35 G40 S41 K43 R73 V102 P103 H104 N105 G106 C107 R108 P109 K110 K111 P80376 QVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4rbb T 2.55 BS01 NUC A 1 L10 S11 A12 K14 R15 H16 R17 S19 R22 R23 N26 K27 A28 K29 S31 A32 K34 T35 L36 K38 K39 L43 E51 K54 R57 E60 S61 D64 K68 S70 H73 K74 N75 A78 R79 K81 S82 R83 M85 R86 R89 G101 G102 G103 L3 S4 A5 K7 R8 H9 R10 S12 R15 R16 N19 K20 A21 K22 S24 A25 K27 T28 L29 K31 K32 L36 E44 K47 R50 E53 S54 D57 K61 S63 H66 K67 N68 A71 R72 K74 S75 R76 M78 R79 R82 G94 G95 G96 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGG 4rbc D 2.55 BS03 MG D 2 G57 H58 R60 L215 G56 H57 R59 L214 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rbc D 2.55 BS06 MG D 5 R52 H220 V221 R222 R51 H219 V220 R221 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rbc G 2.55 BS01 NUC A 1 K36 V38 N40 G42 L43 E45 T71 A73 K74 K75 I77 N79 F80 I88 R91 S124 D126 R128 N130 N132 L133 G134 L135 G154 M155 D156 A158 V160 K35 V37 N39 G41 L42 E44 T70 A72 K73 K74 I76 N78 F79 I87 R90 S123 D125 R127 N129 N131 L132 G133 L134 G153 M154 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rbc G 2.55 BS03 MG G 1 R128 G129 N130 T161 T162 A163 R127 G128 N129 T160 T161 A162 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rbc H 2.55 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 L71 N74 K85 G108 F109 S110 H111 K138 Q139 G142 Q143 A146 R152 K153 Y157 H158 K160 K172 K175 S1 R2 I3 R58 K61 S62 G65 L66 T69 L70 N73 K84 G107 F108 S109 H110 K137 Q138 G141 Q142 A145 R151 K152 Y156 H157 K159 K171 K174 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRLKPGK 4rbc I 2.55 BS01 NUC A 1 K22 G24 Y25 R27 N28 Y29 R33 S42 K45 A46 A49 R50 K22 G24 Y25 R27 N28 Y29 R33 S42 K45 A46 A49 R50 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4rbc O 2.55 BS01 NUC A 1 M1 Q3 P4 Q5 T6 Y7 I22 R23 L25 K26 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K59 K66 K67 E68 K70 R78 N82 M1 Q3 P4 Q5 T6 Y7 I22 R23 L25 K26 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K59 K66 K67 E68 K70 R78 N82 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rbc Q 2.55 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 K22 G23 G24 Y26 A28 F29 A40 W41 Q46 A49 R56 K63 R67 F69 D71 Y74 T75 K76 K77 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 I120 H123 K124 P126 K128 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 K22 G23 G24 Y26 A28 F29 A40 W41 Q46 A49 R56 K63 R67 F69 D71 Y74 T75 K76 K77 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 I120 H123 K124 P126 K128 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rbc Z 2.55 BS01 NUC A 1 K46 G114 I120 I146 G147 H151 E169 K46 G114 I120 I146 G147 H151 E169 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAV 4rbc 0 2.55 BS01 NUC A 1 A2 H3 K4 G8 S9 T10 R11 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 F45 G54 R55 D56 F57 T58 F60 F69 R74 L75 R77 A1 H2 K3 G7 S8 T9 R10 N11 R13 D14 S15 Q16 A17 K18 R19 V22 K23 R24 Y25 E26 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 F44 G53 R54 D55 F56 T57 F59 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4rbc 0 2.55 BS03 MG 0 1 S16 Q17 S15 Q16 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4rbc 1 2.55 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 Q19 R20 R21 A24 K25 R26 G28 G29 V30 G31 K32 K33 T34 T35 I37 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 R50 R52 G55 R61 A64 S65 H66 K69 R76 K78 G79 L80 K81 K92 L97 S1 K2 K9 R10 I12 V13 A14 N15 Q18 R19 R20 A23 K24 R25 G27 G28 V29 G30 K31 K32 T33 T34 I36 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 R49 R51 G54 R60 A63 S64 H65 K68 R75 K77 G78 L79 K80 K91 L96 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4rbc 7 2.55 BS02 MG 7 1 W5 P7 W5 P7 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4rbd B 2.70 BS01 NUC A 1 K22 W24 P26 R96 L98 G99 G100 T103 N104 T107 R111 H140 I172 E176 K179 K16 W18 P20 R90 L92 G93 G94 T97 N98 T101 R105 H134 I166 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rbd E 2.70 BS02 MG E 1 E68 R143 D147 E64 R139 D143 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rbd F 2.70 BS01 NUC A 1 R2 Y4 Y50 K54 V72 N73 R77 R80 R87 V90 K92 R2 Y4 Y50 K54 V72 N73 R77 R80 R87 V90 K92 Q5SLP8 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLAN 4rbd H 2.70 BS01 NUC A 1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 P57 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 R102 R105 S113 T114 S115 G128 V129 G130 G131 E132 L1 T2 D3 P4 A6 D7 T10 R11 R13 N14 R17 V18 K20 A27 S28 R29 F30 K55 P56 R74 K87 P88 G89 R90 R91 Y93 V94 G95 V96 R101 R104 S112 T113 S114 G127 V128 G129 G130 E131 Q5SHQ2 LTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4rbd M 2.70 BS01 NUC A 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 L70 V74 N77 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 K111 R114 K115 T116 V117 K120 K12 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 L69 V73 N76 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 K110 R113 K114 T115 V116 K119 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKK 4rbd O 2.70 BS01 NUC A 1 P2 K8 I12 F18 D21 T22 G23 S24 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 G61 R64 R65 L66 R68 Y69 P1 K7 I11 F17 D20 T21 G22 S23 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 G60 R63 R64 L65 R67 Y68 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4rbe D 2.70 BS05 MG D 4 G41 G42 I49 V51 R52 F53 R54 G40 G41 I48 V50 R51 F52 R53 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4rbe G 2.70 BS01 NUC A 1 K36 V38 N40 G42 L43 G44 E45 K47 T71 A73 K74 K75 I77 N79 F80 I88 R91 S124 F125 D126 R128 N130 N132 L133 L135 G154 M155 D156 V160 K35 V37 N39 G41 L42 G43 E44 K46 T70 A72 K73 K74 I76 N78 F79 I87 R90 S123 F124 D125 R127 N129 N131 L132 L134 G153 M154 D155 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rbe N 2.70 BS02 MG N 1 R35 T43 V46 M48 R35 T43 V46 M48 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rbe Y 2.70 BS01 NUC A 1 M1 R2 K4 K8 K9 S17 G18 K19 K21 V30 P32 Y35 K46 K47 A48 V49 R50 V51 G58 G59 F60 K63 H68 S70 K71 R73 R84 R86 K87 K95 M1 R2 K4 K8 K9 S17 G18 K19 K21 V30 P32 Y35 K46 K47 A48 V49 R50 V51 G58 G59 F60 K63 H68 S70 K71 R73 R84 R86 K87 K95 Q5SHP9 MRVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCGGALD 4rbe 2 2.70 BS01 NUC A 1 M1 K2 L3 R7 L10 R14 K29 S45 Q46 N47 H48 I50 R51 R55 A58 R59 L61 T62 N65 E66 M1 K2 L3 R7 L10 R14 K29 S45 Q46 N47 H48 I50 R51 R55 A58 R59 L61 T62 N65 E66 Q5SHP6 MKLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQ 4rbe 5 2.70 BS03 MG 5 1 A2 K3 A1 K2 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4rbe 6 2.70 BS03 ZN 6 1 C13 C16 C40 W42 C43 C12 C15 C39 W41 C42 P35871 ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4rbe 7 2.70 BS03 MG 7 2 R21 V30 R34 L42 R21 V30 R34 L42 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4rbf B 2.70 BS01 NUC A 1 W24 P26 R96 L98 G99 G100 T103 N104 T107 R111 K133 H140 R144 Y148 E176 K179 W18 P20 R90 L92 G93 G94 T97 N98 T101 R105 K127 H134 R138 Y142 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rbf D 2.70 BS01 NUC A 1 G2 R3 I5 V8 C9 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K85 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 V133 D134 L135 S137 Y138 R141 L155 E156 L157 E205 S208 R209 G1 R2 I4 V7 C8 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K84 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 V132 D133 L134 S136 Y137 R140 L154 E155 L156 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4rbf E 2.70 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 G23 R24 R25 R27 K47 P49 K57 Y61 R64 F84 G85 A86 K92 A94 A95 T98 I101 A102 G103 R107 L119 T120 K121 E122 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 G19 R20 R21 R23 K43 P45 K53 Y57 R60 F80 G81 A82 K88 A90 A91 T94 I97 A98 G99 R103 L115 T116 K117 E118 S121 R122 N123 N126 Y129 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rbf E 2.70 BS02 MG E 1 F84 A86 S87 N130 F80 A82 S83 N126 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rbf J 2.70 BS01 NUC A 1 R9 H13 D17 S35 G36 P37 I38 P39 L40 P41 T42 V44 R45 T48 I50 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 N69 L71 R5 H9 D13 S31 G32 P33 I34 P35 L36 P37 T38 V40 R41 T44 I46 R47 G48 P49 F50 K51 H52 K53 S55 R56 H58 H64 N65 L67 Q5SHN7 RIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4rbf K 2.70 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 V47 G52 S53 K55 K71 R85 P113 V114 H116 N117 G118 C119 R120 P121 K123 Y8 H10 N14 N15 I17 T19 G25 N26 P27 W30 S32 G34 V35 G40 S41 K43 K59 R73 P101 V102 H104 N105 G106 C107 R108 P109 K111 P80376 QVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4rbf O 2.70 BS01 NUC A 1 P2 K5 K8 Q9 I12 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 G61 R64 R65 R68 Y69 R72 E73 P1 K4 K7 Q8 I11 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 G60 R63 R64 R67 Y68 R71 E72 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4rbg G 2.70 BS01 NUC A 1 V38 N40 G42 L43 G44 E45 T71 A73 K74 K75 I77 N79 F80 I88 S124 F125 D126 R128 N130 N132 L133 G134 L135 R136 G154 M155 D156 A158 V160 V37 N39 G41 L42 G43 E44 T70 A72 K73 K74 I76 N78 F79 I87 S123 F124 D125 R127 N129 N131 L132 G133 L134 R135 G153 M154 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rbg G 2.70 BS03 MG G 1 G129 N130 T161 A163 G128 N129 T160 A162 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rbg Q 2.70 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 K18 K22 G24 Y26 F29 A40 W41 Q45 Q46 A49 V52 R56 K63 R67 F69 D71 Y74 K76 K77 E80 R82 M83 G84 K85 G86 K87 G88 R101 R119 I120 H123 K124 L125 P126 K128 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 K18 K22 G24 Y26 F29 A40 W41 Q45 Q46 A49 V52 R56 K63 R67 F69 D71 Y74 K76 K77 E80 R82 M83 G84 K85 G86 K87 G88 R101 R119 I120 H123 K124 L125 P126 K128 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rbg S 2.70 BS02 NUC B 1 K11 R15 R25 F29 R30 S31 L32 K33 Y36 Q38 I40 G45 V46 T47 S50 L54 A55 G60 N61 K62 T63 K93 H95 G96 R97 K9 R13 R23 F27 R28 S29 L30 K31 Y34 Q36 I38 G43 V44 T45 S48 L52 A53 G58 N59 K60 T61 K91 H93 G94 R95 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4rbg U 2.70 BS05 MG U 4 T6 R10 T5 R9 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rbg V 2.70 BS03 MG V 1 E23 K24 Q89 P90 Y91 E23 K24 Q89 P90 Y91 P60492 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4rbg W 2.70 BS03 MG W 2 Y38 T39 N40 Y38 T39 N40 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4rbg X 2.70 BS01 NUC A 1 M1 K2 S14 K16 K25 H31 T35 K36 T37 E38 N41 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 R68 Y69 L70 G71 K72 R73 P74 D75 K77 K78 I80 M1 K2 S14 K16 K25 H31 T35 K36 T37 E38 N41 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 R68 Y69 L70 G71 K72 R73 P74 D75 K77 K78 I80 Q5SHP0 MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL 4rbg Z 2.70 BS01 NUC A 1 K46 Q118 I120 I146 G147 S149 H151 E169 K46 Q118 I120 I146 G147 S149 H151 E169 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAV 4rbh D 2.70 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 R59 K61 Q62 R65 R66 S71 E72 R73 Q74 N77 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 R141 L155 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 R58 K60 Q61 R64 R65 S70 E71 R72 Q73 N76 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 R140 L154 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4rbh E 2.70 BS03 MG E 2 G85 A86 S87 S125 G81 A82 S83 S121 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4rbi H 2.70 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 L64 G66 L67 T70 L71 N74 K85 G108 F109 S110 H111 K138 Q139 G142 Q143 R152 K153 A156 Y157 H158 K160 K172 G174 K175 S1 R2 I3 R58 K61 S62 L63 G65 L66 T69 L70 N73 K84 G107 F108 S109 H110 K137 Q138 G141 Q142 R151 K152 A155 Y156 H157 K159 K171 G173 K174 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRLKPGK 4rbi I 2.70 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 R33 S42 N43 A46 R50 R52 A53 K22 P23 G24 Y25 N28 Y29 R33 S42 N43 A46 R50 R52 A53 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4rbi N 2.70 BS02 MG N 1 R35 W42 L116 R35 W42 L116 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4rbi Q 2.70 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K22 G24 Y26 A28 F29 W41 Q45 Q46 A49 V52 R56 K63 F65 I66 R67 F69 D71 Y74 T75 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K22 G24 Y26 A28 F29 W41 Q45 Q46 A49 V52 R56 K63 F65 I66 R67 F69 D71 Y74 T75 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rbi R 2.70 BS03 MG R 2 R17 Y21 R17 Y21 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4rbi U 2.70 BS03 MG U 2 W25 L27 R28 W24 L26 R27 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rbi U 2.70 BS08 MG U 7 T6 G7 V8 V9 R10 R11 T5 G6 V7 V8 R9 R10 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4rbi V 2.70 BS04 MG V 3 A77 K78 A77 K78 P60492 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4rbi 5 2.70 BS04 MG 5 3 S21 H22 A24 S20 H21 A23 P80339 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4rbj B 2.70 BS01 NUC A 1 K22 W24 P26 R96 L98 G99 G100 T103 N104 T107 R111 K133 H140 R144 Y148 I172 E176 K179 K16 W18 P20 R90 L92 G93 G94 T97 N98 T101 R105 K127 H134 R138 Y142 I166 E170 K173 P80371 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4rbj M 2.70 BS02 NUC W 1 K120 K121 P124 K118 K119 P122 P80377 RIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAP 4rbk G 2.70 BS01 NUC A 1 K36 V38 N40 G42 L43 E45 T71 R72 A73 K74 K75 I77 N79 F80 I88 R91 S124 F125 D126 R128 N130 N132 G134 L135 R136 G154 M155 D156 A158 V160 K35 V37 N39 G41 L42 E44 T70 R71 A72 K73 K74 I76 N78 F79 I87 R90 S123 F124 D125 R127 N129 N131 G133 L134 R135 G153 M154 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4rbk I 2.70 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 R33 S42 A46 A49 R50 A53 K22 P23 G24 Y25 N28 Y29 R33 S42 A46 A49 R50 A53 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4rbk O 2.70 BS02 MG O 1 Y7 N82 Y7 N82 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4rbk Q 2.70 BS04 MG Q 2 K76 K77 P78 N89 E91 K76 K77 P78 N89 E91 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4rbk Z 2.70 BS01 NUC A 1 K46 G114 Q118 I120 I146 G147 H151 T170 K46 G114 Q118 I120 I146 G147 H151 T170 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAV 4rbk 5 2.70 BS03 MG 5 1 K8 K9 K7 K8 P80339 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4rg1 A 1.86 BS01 SAH A 1 T289 S290 E291 R292 F311 G312 G313 L314 G316 V340 N341 T342 Q346 I351 T353 A356 T200 S201 E202 R203 F222 G223 G224 L225 G227 V251 N252 T253 Q257 I262 T264 A267 Q5T280 RGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDEEGQACVQLARILQYLECPQYLRKAFFPKHLQFAGLLNPLDSPHHMRQDEESEFREGIVVDRPTRPGHGSFVNCGMKKEVKIDKNLEPGLRVTVRLNQQQDCKTYHGKVVSSQDPRTKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLPNFRHALVVFGGLQGLEAGADADPNLEVAEPSVLFDLYVNTCPGQGSRTIRTEEAILISLAALQPGLTQAGAR 4rg2 A 1.50 BS01 3OO A 1 Y1502 F1519 D1521 M1584 Y18 F35 D37 M100 Q12888 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4rg2 A 1.50 BS02 UNX A 1 Y1502 S1503 D1520 M1584 Y18 S19 D36 M100 Q12888 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4rg2 A 1.50 BS03 UNX A 2 K1530 R1597 G1603 K46 R113 G119 Q12888 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4rg2 A 1.50 BS04 UNX A 3 P1539 L1540 H1561 P55 L56 H77 Q12888 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4rg2 A 1.50 BS05 UNX B 1 K1582 M1584 A1585 K98 M100 A101 Q12888 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4rg2 B 1.50 BS01 3OO A 1 W1495 D1521 Y1523 M1584 W14 D40 Y42 M103 Q12888 GGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGL 4rg2 B 1.50 BS02 UNX B 2 S1503 D1520 M1584 S22 D39 M103 Q12888 GGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGL 4rg3 A 1.94 BS01 FAD A 1 I14 G15 G17 F18 G19 D39 K40 G46 T47 W48 W50 N51 Y53 S58 D59 T60 Y65 E111 V112 A142 V143 G144 N388 I392 L428 N436 L437 I9 G10 G12 F13 G14 D34 K35 G41 T42 W43 W45 N46 Y48 S53 D54 T55 Y60 E106 V107 A137 V138 G139 N383 I387 L423 N431 L432 1.14.13.22 C0STX7 25265531 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQYSVPVGNRPVNPEQIAEIKADYDRIWERAKNSAVAFGFEESTLPAMSVSEEERNRIFQEAWDHGGGFRFMFGTFGDIATDEAANEAAASFIRAKVAEIIEDPETARKLMPKGLFAKRPLCDSGYYEVYNRPNVEAVAIKENPIREVTAKGVVTEDGVLHELDVLVFATGFDAVDGNYRRIEIRGRDGLHINDHWDGQPTSYLGVSTANFPNWFMVLGPNGPFTNLPPSIETQVEWISDTIGYAERNGVRAIEPTPEAEAEWTETCTEIANATLFTKGDSWIFGANIPGKKPSVLFYLGGLRNYRAVMAEVAADGYRGFEVKS 4rg3 A 1.94 BS02 NAP A 1 Y53 L57 S58 D59 L146 P152 I184 G185 T186 G187 S188 T189 Q192 R209 T210 R329 I350 A379 T380 G381 W492 Y48 L52 S53 D54 L141 P147 I179 G180 T181 G182 S183 T184 Q187 R204 T205 R324 I345 A374 T375 G376 W487 1.14.13.22 C0STX7 25265531 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQYSVPVGNRPVNPEQIAEIKADYDRIWERAKNSAVAFGFEESTLPAMSVSEEERNRIFQEAWDHGGGFRFMFGTFGDIATDEAANEAAASFIRAKVAEIIEDPETARKLMPKGLFAKRPLCDSGYYEVYNRPNVEAVAIKENPIREVTAKGVVTEDGVLHELDVLVFATGFDAVDGNYRRIEIRGRDGLHINDHWDGQPTSYLGVSTANFPNWFMVLGPNGPFTNLPPSIETQVEWISDTIGYAERNGVRAIEPTPEAEAEWTETCTEIANATLFTKGDSWIFGANIPGKKPSVLFYLGGLRNYRAVMAEVAADGYRGFEVKS 4rg3 A 1.94 BS03 ECE A 1 F279 R329 F434 T435 L437 W492 F274 R324 F429 T430 L432 W487 1.14.13.22 C0STX7 25265531 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQYSVPVGNRPVNPEQIAEIKADYDRIWERAKNSAVAFGFEESTLPAMSVSEEERNRIFQEAWDHGGGFRFMFGTFGDIATDEAANEAAASFIRAKVAEIIEDPETARKLMPKGLFAKRPLCDSGYYEVYNRPNVEAVAIKENPIREVTAKGVVTEDGVLHELDVLVFATGFDAVDGNYRRIEIRGRDGLHINDHWDGQPTSYLGVSTANFPNWFMVLGPNGPFTNLPPSIETQVEWISDTIGYAERNGVRAIEPTPEAEAEWTETCTEIANATLFTKGDSWIFGANIPGKKPSVLFYLGGLRNYRAVMAEVAADGYRGFEVKS 4rg4 A 2.51 BS03 ECE A 1 F279 R329 T435 L437 F274 R324 T430 L432 1.14.13.22 C0STX7 25265531 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQYSVPVGNRPVNPEQIAEIKADYDRIWERAKNSAVAFGFEESTLPAMSVSEEERNRIFQEAWDHGGGFRFMFGTFGDIATDEAANEAAASFIRAKVAEIIEDPETARKLMPKGLFAKRPLCDSGYYEVYNRPNVEAVAIKENPIREVTAKGVVTEDGVLHELDVLVFATGFDAVDGNYRRIEIRGRDGLHINDHWDGQPTSYLGVSTANFPNWFMVLGPNGPFTNLPPSIETQVEWISDTIGYAERNGVRAIEPTPEAEAEWTETCTEIANATLFTKLFYLGGLRNYRAVMAEVAADGYRGFEVK 4rg4 A 2.51 BS04 PTD A 1 K40 N388 K35 N383 1.14.13.22 C0STX7 25265531 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQYSVPVGNRPVNPEQIAEIKADYDRIWERAKNSAVAFGFEESTLPAMSVSEEERNRIFQEAWDHGGGFRFMFGTFGDIATDEAANEAAASFIRAKVAEIIEDPETARKLMPKGLFAKRPLCDSGYYEVYNRPNVEAVAIKENPIREVTAKGVVTEDGVLHELDVLVFATGFDAVDGNYRRIEIRGRDGLHINDHWDGQPTSYLGVSTANFPNWFMVLGPNGPFTNLPPSIETQVEWISDTIGYAERNGVRAIEPTPEAEAEWTETCTEIANATLFTKLFYLGGLRNYRAVMAEVAADGYRGFEVK 4rg4 A 2.51 BS05 PTD A 2 E163 K174 S175 R179 E158 K169 S170 R174 1.14.13.22 C0STX7 25265531 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQYSVPVGNRPVNPEQIAEIKADYDRIWERAKNSAVAFGFEESTLPAMSVSEEERNRIFQEAWDHGGGFRFMFGTFGDIATDEAANEAAASFIRAKVAEIIEDPETARKLMPKGLFAKRPLCDSGYYEVYNRPNVEAVAIKENPIREVTAKGVVTEDGVLHELDVLVFATGFDAVDGNYRRIEIRGRDGLHINDHWDGQPTSYLGVSTANFPNWFMVLGPNGPFTNLPPSIETQVEWISDTIGYAERNGVRAIEPTPEAEAEWTETCTEIANATLFTKLFYLGGLRNYRAVMAEVAADGYRGFEVK 4rgb A 1.95 BS01 NAD A 1 G27 A29 R30 G31 Q32 D51 I52 G64 A88 D89 V90 N116 A117 G118 V119 T167 S168 S169 Y186 K190 P216 T217 N218 C219 T221 P222 M223 I224 G12 A14 R15 G16 Q17 D36 I37 G49 A73 D74 V75 N101 A102 G103 V104 T152 S153 S154 Y171 K175 P201 T202 N203 C204 T206 P207 M208 I209 1.1.1.275 A0QDP5 GSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVKR 4rgc A 1.05 BS01 NAP A 1 A6 A7 I14 G15 N18 A19 M20 W22 G43 R44 H45 T46 L62 S63 S64 K76 I94 G96 G97 R98 V99 Y100 Q102 A6 A7 I14 G15 N18 A19 M20 W22 G43 R44 H45 T46 L62 S63 S64 K76 I94 G96 G97 R98 V99 Y100 Q102 1.5.1.3 U6N356 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR 4rgg A 2.15 BS01 GN1 A 1 R237 F240 N289 S291 A292 N341 F343 R234 F237 N286 S288 A289 N338 F340 D3W0F1 VLKGINFDRSIVTPENEASILDLAMQNRSGVLDGMTIDILNTTSNQLALFHGTAVLQGYGIEITRAAAPDVLVDTTGQSNETMLLCLTIDLNQVNVPSGTVGTNTYAVDYKQIRLEFLDVPTLLKQYWRDHSLHDLIDPRRVISMPLYWITFGQTGTTPKYEQIKSNYIDGGNSGNPAYGIAARCENFNHFINKVAVQSIPINGVANRPVSSTASQLTNYKVWRNPYLCSQDPRDKFAPDNLVIEEDGIYRIDISGSINIANYTFPASGNSWRVGGRYFQIVCARNSSANNLAEFGAEQHLPPSGVWTRRVLVGEYTAGMTEQAFSSVATISLFKGDNFFLQFETGTNTSRDSAYNNGYGTSGTHLRNFSYTLERVGDLNGTAYYDNGTF 4tju A 1.57 BS02 CNQ A 1 H1031 G1032 Y1060 F1061 K1067 S1068 Y1071 I1075 E1138 H69 G70 Y97 F98 K104 S105 Y108 I112 E175 2.4.2.30 Q9H2K2 KEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tju B 1.57 BS02 CNQ B 1 H1031 G1032 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 E1138 H74 G75 Y103 F104 A105 K110 S111 Y114 I118 E180 2.4.2.30 Q9H2K2 YFQGDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjw A 1.70 BS02 P34 A 1 H1031 G1032 Y1050 G1052 G1053 G1056 G1058 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 E1138 H69 G70 Y88 G90 G91 G94 G96 Y98 F99 A100 K105 S106 Y109 I113 E176 2.4.2.30 Q9H2K2 KEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4tjw B 1.70 BS02 P34 B 1 H1031 G1032 Y1050 G1052 G1056 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 E1138 H79 G80 Y98 G100 G104 Y108 F109 A110 K115 S116 Y119 I123 E185 2.4.2.30 Q9H2K2 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVGLALAEYVIYRGEQAYPEYLITYQIMRP 4tjy A 1.90 BS02 3GN A 1 H1031 G1032 G1053 Y1060 F1061 K1067 S1068 Y1071 E1138 H70 G71 G92 Y99 F100 K106 S107 Y110 E177 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tk5 A 2.02 BS02 UHB A 1 H1031 G1032 S1033 F1035 A1038 I1039 G1043 F1044 D1045 H1048 A1049 G1058 Y1060 S1068 Y1071 H72 G73 S74 F76 A79 I80 G84 F85 D86 H89 A90 G99 Y101 S109 Y112 2.4.2.30 Q9H2K2 PDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tk5 C 2.02 BS02 UHB C 1 H1031 G1032 S1033 A1038 I1039 G1043 F1044 D1045 H1048 A1049 Y1060 K1067 S1068 Y1071 I1075 H79 G80 S81 A86 I87 G91 F92 D93 H96 A97 Y108 K115 S116 Y119 I123 2.4.2.30 Q9H2K2 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tkg A 1.95 BS02 09L A 1 H1031 G1032 F1035 I1039 F1044 D1045 H1048 Y1050 I1059 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 E1138 H70 G71 F74 I78 F83 D84 H87 Y89 I98 Y99 F100 A101 K106 S107 Y110 I114 E177 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4tkg C 1.95 BS02 09L C 1 H1031 G1032 D1045 H1048 G1058 I1059 Y1060 F1061 A1062 K1067 S1068 Y1071 E1138 H80 G81 D94 H97 G105 I106 Y107 F108 A109 K114 S115 Y118 E185 2.4.2.30 Q9H2K2 ENLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4tkg D 1.95 BS02 09L D 1 H1031 G1032 I1039 D1045 H1048 A1049 I1051 G1058 I1059 Y1060 F1061 A1062 K1067 S1068 Y1071 E1138 H67 G68 I75 D81 H84 A85 I86 G93 I94 Y95 F96 A97 K102 S103 Y106 E173 2.4.2.30 Q9H2K2 FQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4tki A 2.15 BS02 33E A 1 H1031 G1032 S1033 Y1050 Y1060 F1061 K1067 S1068 Y1071 E1138 H70 G71 S72 Y89 Y99 F100 K106 S107 Y110 E177 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tki A 2.15 BS03 33E A 2 F1035 A1038 I1039 G1043 D1045 H1048 F74 A77 I78 G82 D84 H87 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tki A 2.15 BS04 33E A 3 K999 C1001 N1002 K1003 W1006 Y1148 E1150 K38 C40 N41 K42 W45 Y187 E189 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tki C 2.15 BS03 33E C 2 F1035 I1039 G1043 D1045 H1048 F83 I87 G91 D93 H96 2.4.2.30 Q9H2K2 NLYFQGSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRP 4tki D 2.15 BS04 33E D 3 C1001 N1002 K1003 W1006 R1100 Y1148 E1150 C40 N41 K42 W45 R137 Y181 E183 2.4.2.30 Q9H2K2 DKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPLALAEYVIYRGEQAYPEYLITYQIMRP 4tpl A 2.90 BS01 OXN A 1 T2 C15 T13 C26 Q5SBG8 GTENLYFQSNADTGCAIDISRQELRCGSGVFIHNDVEAWMDRYKYYPETPQGLAKIIQKAHKEGVCGLRSVSRLEHQMWEAVKDELNTLLKENGVDLSVVVEKQEGMYKSAPKRLTATANNTFVVDGPETKECPTQNRAWNSLEVEDFGFGLTSTRMFLKVRESNTTECDSKIIGTAVKNNLAIHSDLSYWIESRLNDTWKLERAVLGEVKSCTWPETHTLWGDGILESDLIIPVTLAGPRSNHNRRPGYKTQNQGPWDEGRVEIDFDYCPGTTVTLSESCGHRGPATRTTTESGKLITDWCCRSCTLPPLRYQTDSGCWYGMEIRPQRHDEKTLVQSQVNA 4tpl A 2.90 BS02 OXN B 1 C4 L13 C15 L24 Q5SBG8 GTENLYFQSNADTGCAIDISRQELRCGSGVFIHNDVEAWMDRYKYYPETPQGLAKIIQKAHKEGVCGLRSVSRLEHQMWEAVKDELNTLLKENGVDLSVVVEKQEGMYKSAPKRLTATANNTFVVDGPETKECPTQNRAWNSLEVEDFGFGLTSTRMFLKVRESNTTECDSKIIGTAVKNNLAIHSDLSYWIESRLNDTWKLERAVLGEVKSCTWPETHTLWGDGILESDLIIPVTLAGPRSNHNRRPGYKTQNQGPWDEGRVEIDFDYCPGTTVTLSESCGHRGPATRTTTESGKLITDWCCRSCTLPPLRYQTDSGCWYGMEIRPQRHDEKTLVQSQVNA 4tpl B 2.90 BS01 OXN B 1 T2 C4 C15 T23 C25 C36 Q5SBG8 HHHHSSGVDLGTENLYFQSNADTGCAIDISRQELRCGSGVFIHNDVEAWMDRYKYYPETPQGLAKIIQKAHKEGVCGLRSVSRLEHQMWEAVKDELNTLLKENGVDLSVVVEKQEGMYKSAPKRLTATTNNTFVVDGPETKECPTQNRAWNSLEVEDFGFGLTSTRMFLKVRESNTTECDSKIIGTAVKNNLAIHSDLSYWIESRLNDTWKLERAVLGEVKSCTWPETHTLWGDGILESDLIIPVTLAGPRSNHNRRPGYKTQNQGPWDEGRVEIDFDYCPGTTVTLSESCGHRGPATRTTTESGKLITDWCCRSCTLPPLRYQTDSGCWYGMEIRPQRHDEKTLVQSQVNA 4tug A 3.55 BS01 NUC G 1 R55 R89 R90 R59 R93 R94 Q58719 25107472 RGSHMMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDEFIDMPDN 4tug A 3.55 BS02 NUC H 1 R89 R90 L91 K129 S131 R93 R94 L95 K133 S135 Q58719 25107472 RGSHMMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDEFIDMPDN 4tug B 3.55 BS01 NUC G 1 Y13 R14 Y16 N17 R211 Y13 R14 Y16 N17 R211 Q58719 25107472 MMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDE 4tug B 3.55 BS02 NUC H 1 R14 N17 L18 D19 R89 R90 K129 R14 N17 L18 D19 R89 R90 K129 Q58719 25107472 MMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDE 4tug F 3.55 BS02 MG F 2 D8 H10 D49 H186 H188 D10 H12 D51 H188 H190 Q58719 25107472 SHMMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIV 4tuh A 1.80 BS01 38H A 1 A93 E96 F97 Y101 R102 F105 S106 D107 L108 T109 L130 N136 G138 R139 A142 S145 F146 A149 Y195 A41 E44 F45 Y49 R50 F53 S54 D55 L56 T57 L78 N84 G86 R87 A90 S93 F94 A97 Y143 Q07817 24944740 PLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 4tuh B 1.80 BS01 38H B 1 A93 E96 F97 Y101 R102 F105 S106 D107 L108 T109 E129 L130 N136 G138 R139 S145 F146 A149 L194 Y195 A42 E45 F46 Y50 R51 F54 S55 D56 L57 T58 E78 L79 N85 G87 R88 S94 F95 A98 L143 Y144 Q07817 24944740 GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG 4tui A 3.59 BS01 NUC G 1 R89 R90 R93 R94 Q58719 25107472 RGSHMMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDEFIDMPDN 4tui A 3.59 BS02 NUC H 1 R89 L91 K129 S131 R93 L95 K133 S135 Q58719 25107472 RGSHMMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDEFIDMPDN 4tui B 3.59 BS01 NUC G 1 Q15 Y16 N17 R211 Q15 Y16 N17 R211 Q58719 25107472 MMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDE 4tui B 3.59 BS02 NUC H 1 R14 Y16 N17 L18 D19 K129 R14 Y16 N17 L18 D19 K129 Q58719 25107472 MMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKALRIAMQAFKKLHENNIKVYIVAGNHEMPRRLGEESPLALLKDYVKILDGKDVINVNGEEIFICGTYYHKKSKREEMLDKLKNFESEAKNYKKKILMLHQGINPYIPLDYELEHFDLPKFSYYALGHIHKRILERFNDGILAYSGSTEIIYRNEYEDYKKEGKGFYLVDFSGNDLDISDIEKIDIECREFVEVNIKDKKSFNEAVNKIERCKNKPVVFGKIKREFKPWFDTLKDKILINKAIIVDDE 4tx0 A 1.03 BS01 384 A 1 Y57 F67 D68 R73 F77 Q85 V86 I87 W90 Y113 S118 K121 I122 F130 Y45 F55 D56 R61 F65 Q73 V74 I75 W78 Y101 S106 K109 I110 F118 5.2.1.8 Q13451 25286062 GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE 4u8v B 2.30 BS01 MIY B 1 L177 F178 G179 S180 N274 D276 I277 A279 V612 F615 R620 L177 F178 G179 S180 N274 D276 I277 A279 V612 F615 R620 P31224 25248080 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVNDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRF 4une B 1.59 BS01 III A 1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 K29 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 K29 P01308 25286859 FVNQHLCGSHLVEALYLVCGERGFFFTPKT 4uni A 2.60 BS01 GAL A 1 F59 R125 N163 E164 D291 Y293 E324 W332 F362 E372 H375 F53 R119 N157 E158 D285 Y287 E318 W326 F356 E366 H369 3.2.1.23 C6A6W5 25287704 HRAHRWPQPLPGNDRKIWFGADYNPDQWPEDVQDEDIRLMKQAGVNIVSLAIFSWANIETSDGNFEFDWLDRVIDKLYKAGIAVDLASATASPPMWLTSAHPEVLRRDEQGHVIWPGARQHWRPTSPTFRTYALRLCREMAEHYKDNPAIVSWHVGNEYGCHNYFDYSDDAVQAFREWCRDRYGTIDKVNAAWGTNFWSQRLNSFEEILPPRYVGGEGNFTNPGRLLDFKHFCSDALKEFFCAERDVLSEVTPNIPLTTNFMVSASQNTLDYDDWAHEVDFVSNDHYFTPGSWHIDELAYSASLVDGISRKKPWFLMEQSTSAVNWREINPRKEPGELIRDSMLHLAMGADAICYFQWRQSRSGAEKFHSAMLPLAGEHSQIYRDVCALGADLDTLSDAGILRSKLSKARVAIVQDIQSEWATEHTATPTQHIREWTEPLDWFAAFANRGVTADVTPIHAQWDTYDAVVIPCVYLFSEEMAERLRTFVRNGGKAFVTYYSALADEHDRLHTEGWPGLIGDVVGVRIEEHCPLGTLFPGMLDHLDVSNGTVVHDLADVIDAIADDTTVLATFEADPATGMDGRAAITVHPYHEGGVAYIAGKLGRDGISQSLPEICAALGFELDADPRAGDVLRVVREQEDGAIFEFLFNRTRNTVTADRPAGDMLICSLATDSTDKVTLEPNGVLAFRR 4uoc A 2.46 BS01 NCN A 1 S269 L270 Y296 K301 T340 G341 V342 A343 G344 D346 L348 R377 S269 L270 Y296 K301 T340 G341 V342 A343 G344 D346 L348 R377 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4uoc A 2.46 BS02 NCN B 1 P283 G284 A285 S286 P283 G284 A285 S286 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4uov A 1.85 BS02 AZM A 1 Q110 H112 H114 H131 V133 L197 T198 T199 W208 Q88 H90 H92 H109 V111 L175 T176 T177 W186 4.2.1.1 E8T502 25286845 GAHWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVKACLAPVSVYYVSDAKYVVNNGHTIKVVMGGRGYVVVDGKRFYLKQFHFHAPSEHTVNGKHYPFEAHFVHLDKNGNITVLGVFFKVGKENPELEKVWRVMPEEPGQKRHLTARIDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNNRPVQPLNARKVMK 4uov C 1.85 BS02 AZM C 1 Q110 H112 H114 H131 L197 T198 T199 W208 Q88 H90 H92 H109 L175 T176 T177 W186 4.2.1.1 E8T502 25286845 GAHWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVKACLAPVSVYYVSDAKYVVNNGHTIKVVMGGRGYVVVDGKRFYLKQFHFHAPSEHTVNGKHYPFEAHFVHLDKNGNITVLGVFFKVGKENPELEKVWRVMPEEPGQKRHLTARIDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNNRPVQPLNARKVMK 4uqu A 1.60 BS01 SF4 A 1 S290 R291 M292 I296 C329 C332 K333 K334 C335 C390 P391 F392 S290 R291 M292 I296 C329 C332 K333 K334 C335 C390 P391 F392 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4uqu A 1.60 BS02 SF4 A 2 C339 P340 S341 I344 C372 C383 G384 V385 C386 C339 P340 S341 I344 C372 C383 G384 V385 C386 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4uqu A 1.60 BS03 BVQ A 1 I22 Y31 T36 A37 F38 Y170 T242 Y246 M249 N272 G275 Q276 S277 V278 A279 A289 M292 G293 A294 C295 P302 V304 R305 L306 H357 N358 Q359 K362 Q364 Y369 C372 W376 Y382 C386 V387 I22 Y31 T36 A37 F38 Y170 T242 Y246 M249 N272 G275 Q276 S277 V278 A279 A289 M292 G293 A294 C295 P302 V304 R305 L306 H357 N358 Q359 K362 Q364 Y369 C372 W376 Y382 C386 V387 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur0 B 1.80 BS04 TCV B 1 F38 Y102 T242 Y246 N272 W376 Y382 F34 Y98 T238 Y242 N268 W372 Y378 1.97.1.8 W6EQP0 25278505 KNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRNITEVWDGKINTYGLDADHFRDTVSFRKDRV 4ur1 A 1.65 BS04 CB0 A 1 F38 W56 W96 Y102 T242 Y246 W376 Y382 F38 W56 W96 Y102 T242 Y246 W376 Y382 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLDPLMNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur2 A 2.10 BS04 IOD A 1 F38 Y246 R305 W376 F38 Y246 R305 W376 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur2 A 2.10 BS05 IOD A 2 F38 W96 Y102 Y246 F38 W96 Y102 Y246 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur2 A 2.10 BS06 IOD A 3 R152 V159 S455 R460 R152 V159 S438 R443 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur2 A 2.10 BS07 IOD A 4 R30 V195 F196 R30 V195 F196 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur2 A 2.10 BS08 IOD A 5 T232 N235 N431 I432 T232 N235 N414 I415 1.97.1.8 W6EQP0 25278505 AEKEKNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur2 B 2.10 BS08 IOD B 5 R109 P177 A178 K192 R103 P171 A172 K186 1.97.1.8 W6EQP0 25278505 AAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKNITEVWDGKINTYGLDADHFRDTVSFRKDRV 4ur3 A 2.24 BS03 BVQ A 1 Y31 T36 A37 F38 Y170 Y246 M249 N272 G275 Q276 S277 V278 A289 M292 G293 A294 C295 V304 R305 L306 H357 N358 Q359 K362 Q364 Y369 C372 W376 Y382 C386 V387 Y27 T32 A33 F34 Y166 Y242 M245 N268 G271 Q272 S273 V274 A285 M288 G289 A290 C291 V300 R301 L302 H353 N354 Q355 K358 Q360 Y365 C368 W372 Y378 C382 V383 1.97.1.8 W6EQP0 25278505 KNAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTRFLDPLMLGMDDALGYGAKRNITEVWDGKINTYGLDADHFRDTVSFRKDRVK 4ur3 B 2.24 BS01 SF4 B 1 S290 R291 M292 I296 F328 C329 C332 K334 C335 C390 P391 F392 S285 R286 M287 I291 F323 C324 C327 K329 C330 C385 P386 F387 1.97.1.8 W6EQP0 25278505 NAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNTNITEVWDGKINTYGLDADHFRDTVSFRKDRV 4ur3 E 2.24 BS01 SF4 E 1 S290 R291 M292 C329 C332 K334 C335 C390 P391 F392 S285 R286 M287 C324 C327 K329 C330 C385 P386 F387 1.97.1.8 W6EQP0 25278505 NAAEIRQQFAMTAGSPIIVNDKLERYAEVRTAFTHPTSFFKPNYKGEVKPWFLSAYDEKVRQIENGENGPKMKAKNVGEARAGRALEAAGWTLDINYGNIYPNRFFMLWSGETMTNTQLWAPVGLDRRPPDTTDPVELTNYVKFAARMAGADLVGVARLNRNWVYSEAVTIPADVPYEQSLHKEIEKPIVFKDVPLPIETDDELIIPNTCENVIVAGIAMNREMMQTAPNSMACATTAFCYSRMCMFDMWLCQFIRYMGYYAIPSCNGVGQSVAFAVEAGLGQASRMGACITPEFGPNVRLTKVFTNMPLVPDKPIDFGVTEFCETCKKCARECPSKAITEGPRTFEGRSIHNQSGKLQWQNDYNKCLGYWPESGGYCGVCVAVCPFTKGNIWIHDGVEWLIDNNITEVWDGKINTYGLDADHFRDTVSFRKDRV 4utu A 1.45 BS01 LRY A 1 Q14 R43 I64 Y75 T147 Y151 E180 G181 R182 G203 G204 R208 Q23 R52 I73 Y84 T156 Y160 E189 G190 R191 G212 G213 R217 5.1.3.9 Q8XNZ3 GSSHHHHHHMLDVVKGNLIVSCQALSDEPLHSSFIMGRMAIAAKQGGAAAIRAQGVNDINEIKEVTKLPIIGIIARNYDDSEIYITPTMKEVDELLKTDCEMIALDATKRKRPNGENVKDLVDAIHAKGRLAMADISTLEEGIEAEKLGFDCVSTTLSGYTPYSKQSNSVDFELLEELVKTVKIPVICEGRINTPEELKKALDLGAYSAVVGGAITRPQQITKRFTDIL 4utw C 1.90 BS01 RFW C 1 Q14 R43 I64 K66 Y75 I76 T147 L148 Y151 E180 G181 R182 G203 G204 R208 Q23 R52 I73 K75 Y84 I85 T156 L157 Y160 E189 G190 R191 G212 G213 R217 5.1.3.9 Q0TUP9 GSSHHHHHHMLDVVKGNLIVSCQALSDEPLHSSFIMGRMAIAAKQGGAAAIRAQGVNDINEIKEVTKLPIIGIIKRNYDDSEIYITPTMKEVDELLKTDCEMIALDATKRKRPNGENVKDLVDAIHAKGRLAMADISTLEEGIEAEKLGFDCVSTTLSGYTPYSKQSNSVDFELLEELVKTVKIPVICEGRINTPEELKKALDLGAYSAVVGGAITRPQQITKRFTDIL 4utw D 1.90 BS01 RFW D 1 Q14 R43 I64 K66 Y75 T147 L148 Y151 E180 R182 G203 G204 R208 Q23 R52 I73 K75 Y84 T156 L157 Y160 E189 R191 G212 G213 R217 5.1.3.9 Q0TUP9 GSSHHHHHHMLDVVKGNLIVSCQALSDEPLHSSFIMGRMAIAAKQGGAAAIRAQGVNDINEIKEVTKLPIIGIIKRNYDDSEIYITPTMKEVDELLKTDCEMIALDATKRKRPNGENVKDLVDAIHAKGRLAMADISTLEEGIEAEKLGFDCVSTTLSGYTPYSKQSNSVDFELLEELVKTVKIPVICEGRINTPEELKKALDLGAYSAVVGGAITRPQQITKRFTDIL 4uuw A 1.98 BS01 AMP A 1 E12 L13 T18 L19 D20 T21 N22 P153 E12 L13 T18 L19 D20 T21 N22 P153 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVREEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4uux A 1.99 BS01 APR A 1 L13 T18 L19 D20 T21 N22 G68 G69 L70 G71 D76 Q118 T134 A135 P151 G152 P153 E156 L13 T18 L19 D20 T21 N22 G68 G69 L70 G71 D76 Q118 T134 A135 P151 G152 P153 E156 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVRGEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4uux B 1.99 BS01 APR B 1 L13 L19 D20 T21 N22 G68 G69 L70 G71 D76 Q118 N130 G133 T134 A135 P151 G152 P153 E156 L13 L19 D20 T21 N22 G68 G69 L70 G71 D76 Q118 N130 G133 T134 A135 P151 G152 P153 E156 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVRGEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4uux B 1.99 BS02 MG B 1 G71 D76 G71 D76 Q5SHB0 MERAEILGVGTELLYGETLDTNTAEIARSLKPYALKVERTLRVADEVAPLAREVEEAFARARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEIEAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVLLPGPPPEWRPMWQEVLPRLGLPRRPYAERVLKTWGIGESEIVERLGPLFVRGEEVEVGTYPKVHGVEVVVRGREDRVAELAERIKKKLLKEVWGEGEMTLAEAVKRRMEREGATLSTMESLTGGLLGAEITRVPGASRFYLGGVVSYSVGAKARFGVPQDLLSRTVSAETARAMAEAARSLFGSTYALATTGVAGPDPLEGEPPGTVYVALAGPTGAEVRRYRFPGDRETVRLRSVYAALALLVT 4uy1 A 2.20 BS02 TJM A 1 L5 V9 P17 Y20 F26 G28 C43 H46 D47 I94 L98 L5 V9 P17 Y20 F26 G28 C43 H46 D47 I94 L98 3.1.1.4 GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKC 4uy1 B 2.20 BS02 TJM B 1 I2 L5 A6 P17 Y20 M21 F26 G28 C43 H46 D47 I94 L98 I2 L5 A6 P17 Y20 M21 F26 G28 C43 H46 D47 I94 L98 3.1.1.4 O15496 GILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD 4v06 A 2.63 BS01 FE A 1 H318 H323 E363 H177 H182 E222 1.14.16.4 Q8IWU9 LYFQSMLEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI 4v24 A 1.80 BS01 GYR A 1 F259 I260 V263 D264 F278 T282 L347 L354 M358 A360 F374 L388 F389 M392 H397 L405 F167 I168 V171 D172 F186 T190 L249 L256 M260 A262 F276 L290 F291 M294 H299 L307 2.7.1.91 Q9NYA1 PRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVS 4w7p A 2.80 BS01 3J7 A 1 I82 V90 A103 K105 V137 M153 E154 Y155 M156 D160 D202 L205 D216 F368 I77 V85 A98 K100 V129 M145 E146 Y147 M148 D152 D194 L197 D208 F357 2.7.11.1 Q13464 25248678 SFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEETFPIPKAFVGNQLPFVGFTYYSNRRY 4w8x A 3.00 BS01 3GP A 1 P30 A35 W38 W39 S148 S153 R154 W279 P30 A35 W38 W39 S148 S153 R154 W272 Q8U1S5 25280103 MFIEEFEIESITSTHLLEVLTREYPEVRSPSIKGAMRWWFRALAGSYFGDDAQKLKEIENQVFGSTKERSRVKISVTPLSSPKRLNLKEFKDKNVGYIWFSINLLGKRGTITHYYPPGSRFRVVLESPSERVIKLATLSLWALVSLGSVGFRSRRGTGSMKIVRASSEVLEDLGLTTEFNSIDEFKDSLKRVLDVTGEILGVSLPSYATLKFSDVEVFGPGKNTWEVLAQFNNSYKEYLRRRIKKYQRIIFGLPRFKLRGVRKDLRRASPLWFGVVEIGGKPYGRIIKFFQSTFHPEVRSKHIVDWNVLSNFDWFISSRLPVTKVWGGW 4w8y A 3.00 BS01 ZN A 1 C448 C451 C478 C481 C434 C437 C464 C467 Q8U1S6 25280103 MVNIKEKLFVYLHDPPDKALKIENHEERSKKILSSGNIQDKVKQADALSSKTQRFIIREPVIDFLGRFHVGYPVFIHPISTEIKRYETLEKYIDLGRSNRGERFVNEFLERVSKLEGDVLKEVFEDASNKFKGEESKQWAYIWQFYPVKLKEGVKEFAKSELKLKEEEAEKFAEEFVNLPADTRFPDHAIWTHLDLTSALSVKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGLSIDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLGEISTRIHPNIRDYVEIPEAKYYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFENGSLLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLERFIYHVLREVDTWPIDEMLKFEVIRHIKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 4w8y A 3.00 BS02 MN A 1 D14 K18 H25 D14 K18 H25 Q8U1S6 25280103 MVNIKEKLFVYLHDPPDKALKIENHEERSKKILSSGNIQDKVKQADALSSKTQRFIIREPVIDFLGRFHVGYPVFIHPISTEIKRYETLEKYIDLGRSNRGERFVNEFLERVSKLEGDVLKEVFEDASNKFKGEESKQWAYIWQFYPVKLKEGVKEFAKSELKLKEEEAEKFAEEFVNLPADTRFPDHAIWTHLDLTSALSVKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGLSIDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLGEISTRIHPNIRDYVEIPEAKYYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFENGSLLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLERFIYHVLREVDTWPIDEMLKFEVIRHIKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 4w8y A 3.00 BS03 MN A 2 H13 D14 K18 D50 H207 H13 D14 K18 D46 H193 Q8U1S6 25280103 MVNIKEKLFVYLHDPPDKALKIENHEERSKKILSSGNIQDKVKQADALSSKTQRFIIREPVIDFLGRFHVGYPVFIHPISTEIKRYETLEKYIDLGRSNRGERFVNEFLERVSKLEGDVLKEVFEDASNKFKGEESKQWAYIWQFYPVKLKEGVKEFAKSELKLKEEEAEKFAEEFVNLPADTRFPDHAIWTHLDLTSALSVKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGLSIDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLGEISTRIHPNIRDYVEIPEAKYYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFENGSLLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLERFIYHVLREVDTWPIDEMLKFEVIRHIKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 4w8y A 3.00 BS04 MN A 3 D600 D673 D674 D578 D651 D652 Q8U1S6 25280103 MVNIKEKLFVYLHDPPDKALKIENHEERSKKILSSGNIQDKVKQADALSSKTQRFIIREPVIDFLGRFHVGYPVFIHPISTEIKRYETLEKYIDLGRSNRGERFVNEFLERVSKLEGDVLKEVFEDASNKFKGEESKQWAYIWQFYPVKLKEGVKEFAKSELKLKEEEAEKFAEEFVNLPADTRFPDHAIWTHLDLTSALSVKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGLSIDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLGEISTRIHPNIRDYVEIPEAKYYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFENGSLLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLERFIYHVLREVDTWPIDEMLKFEVIRHIKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 4w8y A 3.00 BS05 MN A 4 E656 E694 E700 E634 E672 E678 Q8U1S6 25280103 MVNIKEKLFVYLHDPPDKALKIENHEERSKKILSSGNIQDKVKQADALSSKTQRFIIREPVIDFLGRFHVGYPVFIHPISTEIKRYETLEKYIDLGRSNRGERFVNEFLERVSKLEGDVLKEVFEDASNKFKGEESKQWAYIWQFYPVKLKEGVKEFAKSELKLKEEEAEKFAEEFVNLPADTRFPDHAIWTHLDLTSALSVKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGLSIDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLGEISTRIHPNIRDYVEIPEAKYYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFENGSLLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLERFIYHVLREVDTWPIDEMLKFEVIRHIKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 4w8y B 3.00 BS02 MN B 1 H13 D14 K18 H207 H13 D14 K18 H195 Q8U1S6 25280103 MVNIKEKLFVYLHDPPDKALKIENHEERSKKILSSGNITDKVKQADALSSKTQRFIIREPVIDFLGRSYFHVGYPVFIHPISTEIKRYETLEKYIDLGRSNRGERFVNEFLERVSKLEGDVLKEVFEDASNKFKGEESKQWAYIWQFYPVKLKEGVKEFAKSELKLKEEEAEKFAEEFVNLPADTRFPDHAIWTHLDLTSALSVKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEEEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLGEISTRIHPNIRDYVEIPEAKYYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFENGSLLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLERFIYHVLREVDTWPIDEMLKFEVIRHIKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 4w90 B 3.12 BS01 NUC C 1 Y13 N15 N16 L44 S48 L49 K50 M51 R52 G53 Q54 F56 Y86 A87 K88 T89 D90 S91 D92 Y7 N9 N10 L38 S42 L43 K44 M45 R46 G47 Q48 F50 Y80 A81 K82 T83 D84 S85 D86 P09012 25271255 RPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAK 4w9n A 1.84 BS01 TCL B 1 L1753 F1766 L1780 I1784 V1789 F1791 L220 F233 L241 I245 V250 F252 2.3.1.39 P49327 HAFVSTLTRGDLSSIRWVCSRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPE 4w9n B 1.84 BS01 TCL B 1 F1766 L1780 I1784 V1789 F1791 F222 L231 I235 V240 F242 2.3.1.39 P49327 HAFVSTLTRGDLSSIRWVCAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE 4w9n D 1.84 BS01 TCL D 1 L1753 F1766 I1784 V1789 F1791 L212 F225 I235 V240 F242 2.3.1.39 P49327 HAFVSTLTRGDLSSIRWVCCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQHIGKVVVQVLAEEP 4wg3 A 2.20 BS01 UWA A 1 L57 K59 V65 A78 K80 M112 L126 E129 Y131 L181 D195 F196 L198 L15 K17 V23 A36 K38 M70 L84 E87 Y89 L139 D153 F154 L156 2.7.11.17 Q9BJF5 STAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 4wg4 A 2.30 BS01 UWB A 1 V65 A78 K80 M112 L126 E129 Y131 E135 E178 L181 D195 F196 L198 V23 A36 K38 M70 L84 E87 Y89 E93 E136 L139 D153 F154 L156 2.7.11.17 Q9BJF5 STAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 4wg5 A 2.30 BS01 UW3 A 1 G58 V65 A78 K80 L103 M112 L126 E129 V130 Y131 L181 I194 D195 F196 L198 G15 V22 A35 K37 L60 M69 L83 E86 V87 Y88 L138 I151 D152 F153 L155 2.7.11.17 Q9BJF5 TAIFSDRYKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFEDKGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN 4wh8 A 2.70 BS01 3M7 A 1 Q1041 F1043 H1057 G1058 V1078 D1081 L1135 K1136 G1137 A1139 F1154 R1155 A1156 A1157 C1159 Q60 F62 H76 G77 V97 D100 L154 K155 G156 A158 F173 R174 A175 A176 C178 A8DG50 25243902 HMASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSAGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVESLETTM 4wh8 B 2.70 BS01 3M7 B 1 Q1041 F1043 H1057 G1058 V1078 D1081 R1123 I1132 L1135 K1136 G1137 A1139 F1154 R1155 A1156 A1157 Q60 F62 H76 G77 V97 D100 R142 I151 L154 K155 G156 A158 F173 R174 A175 A176 A8DG50 25243902 HMASMKKKGSVVIVGRINLSGDTAYAQQTRGEEGCQETSQTGRDKNQVEGEVQIVSTATQTFLATSINGVLWTVYHGAGTRTIASPKGPVTQMYTNVDKDLVGWQAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSAGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVESLETTM