1vvl B 3.22 BS01 NUC A 1 W24 P26 R96 G99 G100 T103 N104 T107 R111 K133 Y148 I172 E176 K179 W21 P23 R93 G96 G97 T100 N101 T104 R108 K130 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vvl C 3.22 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 S154 R156 E161 Q162 A163 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 S153 R155 E160 Q161 A162 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 R189 T191 Y192 G193 V194 G196 K198 P80372 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGE 1vvl D 3.22 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 L58 R59 K61 Q62 R66 E72 R73 Q74 R76 N77 K85 K86 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 K151 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 L57 R58 K60 Q61 R65 E71 R72 Q73 R75 N76 K84 K85 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 K150 L154 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 1vvl E 3.22 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 A48 P49 K57 Y60 Y61 G85 A86 K92 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 A44 P45 K53 Y56 Y57 G81 A82 K88 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 1vvl G 3.22 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R94 S98 R102 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R93 S97 R101 R113 R114 A115 R118 W155 P17291 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 1vvl H 3.22 BS01 NUC A 1 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 A28 S29 R30 F31 K56 P57 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 V129 G130 E132 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 A28 S29 R30 F31 K56 P57 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 V129 G130 E132 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vvl H 3.22 BS02 MG H 1 R102 R105 R102 R105 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vvl I 3.22 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 R16 F18 R20 Y36 Q38 G39 R42 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 R15 F17 R19 Y35 Q37 G38 R41 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 1vvl J 3.22 BS01 NUC A 1 R5 R9 H13 K14 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 K99 R3 R7 H11 K12 D15 S33 G34 P35 I36 P37 L38 P39 T40 R41 V42 R43 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 K97 Q5SHN7 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV 1vvl K 3.22 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 V47 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 H12 N16 N17 I19 T21 G27 N28 P29 W32 S34 G36 V37 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vvl L 3.22 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K17 K20 S22 K28 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 T61 Y69 P71 G72 E73 G74 R86 G87 V90 K91 D92 P94 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K13 K16 S18 K24 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 P67 G68 E69 G70 R82 G83 V86 K87 D88 P90 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 1vvl M 3.22 BS01 NUC A 1 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 V74 N77 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 P113 R114 K115 T116 V117 K121 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 V73 N76 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 P112 R113 K114 T115 V116 K120 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vvl N 3.22 BS01 NUC A 1 A2 R3 K4 A5 L6 K9 F16 K17 V18 R19 Y21 T22 C27 R29 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 K8 F15 K16 V17 R18 Y20 T21 C26 R28 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 1vvl O 3.22 BS01 NUC A 1 P2 K5 K8 Q9 D21 T22 G23 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 G61 Q62 R64 R65 L66 R68 Y69 R72 P1 K4 K7 Q8 D20 T21 G22 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 G60 Q61 R63 R64 L65 R67 Y68 R71 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 1vvl P 3.22 BS01 NUC A 1 M1 K3 R5 L6 R8 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 D29 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 S61 V62 G63 Q65 T67 T69 R72 R75 F80 R81 Q82 M1 K3 R5 L6 R8 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 D29 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 S61 V62 G63 Q65 T67 T69 R72 R75 F80 R81 Q82 Q5SJH3 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 1vvl Q 3.22 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 R63 P64 I65 S66 K67 R68 K69 R70 R72 K87 R91 R92 N94 Y95 S97 L98 K100 R101 P1 K2 K3 S11 K13 M14 Q15 K16 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 R62 P63 I64 S65 K66 R67 K68 R69 R71 K86 R90 R91 N93 Y94 S96 L97 K99 R100 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 1vvl T 3.22 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 R25 N26 K27 A28 K29 S31 T35 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 R18 N19 K20 A21 K22 S24 T28 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R82 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vvm D 3.22 BS01 NUC A 1 K7 P8 Y9 T10 S12 R13 R14 F15 V18 F21 L37 K38 K39 G42 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 R54 G55 G56 H58 K59 R60 L61 Y62 R63 Y84 P86 R88 D99 G100 E101 K102 L147 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 P178 S179 E181 R183 A199 H201 K202 V205 L206 G207 K208 A209 G210 R211 S212 R213 W214 L215 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 H233 G236 E237 G238 R239 A240 P241 R242 G243 R244 P245 P246 A247 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 K261 R262 R263 K264 S266 R268 F269 I270 K6 P7 Y8 T9 S11 R12 R13 F14 V17 F20 L36 K37 K38 G41 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 R53 G54 G55 H57 K58 R59 L60 Y61 R62 Y83 P85 R87 D98 G99 E100 K101 L146 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 P177 S178 E180 R182 A198 H200 K201 V204 L205 G206 K207 A208 G209 R210 S211 R212 W213 L214 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 H232 G235 E236 G237 R238 A239 P240 R241 G242 R243 P244 P245 A246 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 K260 R261 R262 K263 S265 R267 F268 I269 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIAR 1vvm D 3.22 BS02 MG D 1 N45 Q46 N44 Q45 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIAR 1vvm E 3.22 BS01 NUC A 1 M11 T12 R13 Q35 R37 K41 D42 Y44 Q48 R58 N60 R61 P62 K64 R76 I77 L78 R79 E80 R82 K109 G110 R111 G112 F113 G115 M117 K118 R119 N121 F122 A123 G124 P126 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 K154 K155 M156 A157 H159 Y160 R164 V165 T166 M168 N169 L170 K185 A187 V188 P189 G190 P191 N192 K202 K203 M11 T12 R13 Q35 R37 K41 D42 Y44 Q48 R58 N60 R61 P62 K64 R76 I77 L78 R79 E80 R82 K109 G110 R111 G112 F113 G115 M117 K118 R119 N121 F122 A123 G124 P126 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 K154 K155 M156 A157 H159 Y160 R164 V165 T166 M168 N169 L170 K185 A187 V188 P189 G190 P191 N192 K202 K203 Q5SHN8 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAA 1vvm F 3.22 BS01 NUC A 1 N29 H31 W34 E35 R38 Q40 L41 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 L101 P102 K103 K104 V105 R106 K135 T136 R165 R168 N169 P171 V174 T175 A177 E179 G180 N182 Y184 R205 N24 H26 W29 E30 R33 Q35 L36 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 Q62 K63 H64 G66 R67 A68 R69 H70 G71 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 L96 P97 K98 K99 V100 R101 K130 T131 R160 R163 N164 P166 V169 T170 A172 E174 G175 N177 Y179 R200 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vvm F 3.22 BS02 MG F 1 R168 V173 R163 V168 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vvm G 3.22 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 T71 A73 K74 K75 I77 N79 F80 L82 I88 R91 D126 R128 N130 N132 G134 D156 A158 K35 N39 G41 G43 E44 K46 T70 A72 K73 K74 I76 N78 F79 L81 I87 R90 D125 R127 N129 N131 G133 D155 A157 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvm G 3.22 BS02 NUC B 1 P2 N27 V28 W29 E30 R33 Q66 K67 P68 A69 V70 T71 R72 R91 V92 T93 R95 R96 R98 P1 N26 V27 W28 E29 R32 Q65 K66 P67 A68 V69 T70 R71 R90 V91 T92 R94 R95 R97 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvm H 3.22 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 F109 S110 H111 K138 Q139 G142 Q143 A146 R152 Y157 H158 K160 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 F108 S109 H110 K137 Q138 G141 Q142 A145 R151 Y156 H157 K159 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 1vvm I 3.22 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 R33 S42 K45 A46 R50 R52 K56 K22 P23 G24 Y25 N28 Y29 R33 S42 K45 A46 R50 R52 K56 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vvm N 3.22 BS01 NUC A 1 K2 T3 V5 W13 L23 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 G64 K65 K66 Q69 K70 R74 Y75 S76 Y78 G80 G81 L82 K83 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 K118 K121 P129 Q131 K2 T3 V5 W13 L23 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 G64 K65 K66 Q69 K70 R74 Y75 S76 Y78 G80 G81 L82 K83 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 K118 K121 P129 Q131 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vvm O 3.22 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 K26 S28 N29 A30 K31 Y32 S42 K44 K66 K67 E68 K70 R78 M1 Q3 Q5 T6 Y7 I22 R23 K26 S28 N29 A30 K31 Y32 S42 K44 K66 K67 E68 K70 R78 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 1vvm P 3.22 BS01 NUC A 1 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 G20 R21 P23 G24 S25 G28 K29 T30 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 K46 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 G20 R21 P23 G24 S25 G28 K29 T30 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 K46 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vvm P 3.22 BS02 MG P 1 E52 T58 E52 T58 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vvm Q 3.22 BS01 NUC A 1 P4 R5 R6 K8 Y9 R10 K11 Q13 R14 G15 R16 K18 T21 K22 G23 Y26 W41 Q45 Q46 A49 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 R10 K11 Q13 R14 G15 R16 K18 T21 K22 G23 Y26 W41 Q45 Q46 A49 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vvm Q 3.22 BS02 NUC B 1 R16 L17 A20 R16 L17 A20 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vvm R 3.22 BS01 NUC A 1 M1 R2 H3 L4 K5 S6 R8 K9 N11 R12 H13 S14 S15 H16 R17 A19 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 K40 K42 R45 G46 D49 H50 H53 R57 H61 R63 R64 L65 L67 R68 Q71 V73 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 V117 M1 R2 H3 L4 K5 S6 R8 K9 N11 R12 H13 S14 S15 H16 R17 A19 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 K40 K42 R45 G46 D49 H50 H53 R57 H61 R63 R64 L65 L67 R68 Q71 V73 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 V117 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 1vvm R 3.22 BS02 MG R 1 R2 H3 K5 R2 H3 K5 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 1vvm S 3.22 BS02 NUC B 1 R10 K11 R15 K19 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 I40 G45 V46 T47 S50 L54 A55 K57 N61 K62 T63 Y92 K93 H95 R97 R9 K10 R14 K18 R24 F28 R29 S30 L31 K32 H33 Y35 Q37 I39 G44 V45 T46 S49 L53 A54 K56 N60 K61 T62 Y91 K92 H94 R96 Q5SHQ4 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 1vvm U 3.22 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 V9 R10 R11 R12 K13 H14 K15 K16 K19 K22 G23 Y24 W25 G26 L27 R28 K30 S31 F32 R33 K34 R36 E37 A41 A42 Y45 Y47 H49 R50 K51 R52 R53 K54 R55 D56 F57 R58 R59 W61 I62 V63 N66 R70 N75 Y76 S77 H81 R92 K93 N94 Q117 P1 R2 A3 K4 T5 G6 V7 V8 R9 R10 R11 K12 H13 K14 K15 K18 K21 G22 Y23 W24 G25 L26 R27 K29 S30 F31 R32 K33 R35 E36 A40 A41 Y44 Y46 H48 R49 K50 R51 R52 K53 R54 D55 F56 R57 R58 W60 I61 V62 N65 R69 N74 Y75 S76 H80 R91 K92 N93 Q116 P60491 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQG 1vvm W 3.22 BS01 NUC A 1 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I95 I96 K97 K98 R99 H102 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I95 I96 K97 K98 R99 H102 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK 1vvm X 3.22 BS01 NUC A 1 S14 E15 K16 K25 H31 T35 K36 T37 E38 K40 N41 E44 K50 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 Y69 L70 G71 K72 R73 P74 D75 K77 K78 I80 S12 E13 K14 K23 H29 T33 K34 T35 E36 K38 N39 E42 K48 K51 N53 T54 L55 H56 R58 K60 K61 K62 R63 L64 Y67 L68 G69 K70 R71 P72 D73 K75 K76 I78 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vvm Y 3.22 BS01 NUC A 1 K4 H6 K8 K9 S17 G18 K19 K21 P32 Y35 I44 V45 K47 V49 V51 G59 F60 H68 S70 K71 R73 P82 R84 V85 E91 K3 H5 K7 K8 S16 G17 K18 K20 P31 Y34 I43 V44 K46 V48 V50 G58 F59 H67 S69 K70 R72 P81 R83 V84 E90 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vvm Z 3.22 BS01 NUC A 1 I120 I146 H151 E169 T170 I120 I146 H151 E169 T170 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvm Z 3.22 BS02 NUC B 1 R10 K14 R19 Y29 N30 R31 N34 R72 Q73 N75 R79 E84 H85 D87 F89 R10 K14 R19 Y29 N30 R31 N34 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvm 0 3.22 BS01 NUC A 1 H3 K4 G8 S9 T10 R11 N12 R14 D15 S16 Q17 A18 K19 R20 L21 V23 K24 R25 Y26 E27 G28 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 F60 F69 R74 L75 R77 H2 K3 G7 S8 T9 R10 N11 R13 D14 S15 Q16 A17 K18 R19 L20 V22 K23 R24 Y25 E26 G27 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 G53 R54 D55 F56 F59 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vvm 1 3.22 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 R26 G28 V30 G31 K32 K33 T34 T35 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 R61 S65 H66 K69 R76 K78 K88 E93 L94 L97 L98 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 R25 G27 V29 G30 K31 K32 T33 T34 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 R60 S64 H65 K68 R75 K77 K87 E92 L93 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 1vvm 2 3.22 BS01 NUC A 1 S4 E5 R7 L10 R14 Q46 N47 H48 I50 R51 K54 R55 A58 R59 L61 T62 N65 E66 R69 S1 E2 R4 L7 R11 Q43 N44 H45 I47 R48 K51 R52 A55 R56 L58 T59 N62 E63 R66 Q5SHP6 SEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 1vvm 3 3.22 BS01 NUC A 1 K10 S11 I13 G14 Y15 K17 D18 A21 A22 K24 A25 R29 R30 L31 Q32 P41 A42 I43 G45 N46 K49 K9 S10 I12 G13 Y14 K16 D17 A20 A21 K23 A24 R28 R29 L30 Q31 P40 A41 I42 G44 N45 K48 Q5SHQ6 PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 1vvm 4 3.22 BS01 NUC B 1 M1 K2 M1 K2 Q5SJE1 MKEGIHPKLVPARIICGCGNVIETYSTKPEIYVEVCSKCHPFYTGQQRFVDTEGRVERFQRRYGDSYRKGR 1vvm 6 3.22 BS01 NUC A 1 V5 R6 K8 T23 E24 K25 K27 R28 T30 P31 R37 K38 Y39 C40 W42 K45 H46 V1 R2 K4 T19 E20 K21 K23 R24 T26 P27 R33 K34 Y35 C36 W38 K41 H42 P35871 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 1vvm 7 3.22 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 P25 R28 K29 V30 K32 R33 R34 R35 Q36 K37 R39 W40 R41 P44 R47 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 P25 R28 K29 V30 K32 R33 R34 R35 Q36 K37 R39 W40 R41 P44 R47 K48 R49 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 1vvm 8 3.22 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 G9 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 S37 K39 I41 R42 Q43 R46 F48 V49 K52 L61 L62 Y64 E65 P1 K2 M3 K4 T5 H6 K7 G8 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 S36 K38 I40 R41 Q42 R45 F47 V48 K51 L60 L61 Y63 E64 Q5SKU1 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 1vvm 9 3.22 BS01 NUC A 1 M1 V3 R4 A5 S6 V7 K8 I10 K15 V16 I17 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 V3 R4 A5 S6 V7 K8 I10 K15 V16 I17 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 P80256 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 1vvn G 3.22 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 R76 R94 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 R75 R93 S97 R101 N108 R113 R114 A115 R118 W155 P17291 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 1vvn M 3.22 BS03 MG M 1 R11 N12 R10 N11 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vvn T 3.22 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 R22 R23 R25 N26 K27 A28 K29 S31 A32 K34 T35 L36 K38 K39 E51 R57 E60 D64 K65 K68 S70 K74 A78 R79 K81 S82 R83 M85 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 R15 R16 R18 N19 K20 A21 K22 S24 A25 K27 T28 L29 K31 K32 E44 R50 E53 D57 K58 K61 S63 K67 A71 R72 K74 S75 R76 M78 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vvo F 3.22 BS01 NUC A 1 N29 H31 W34 E35 R38 W39 Q40 L41 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 V57 A58 Y59 S60 G61 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 P102 K103 K104 R106 K135 T136 L140 R165 R168 N169 P171 V174 T175 A177 E179 G180 N182 Y184 N24 H26 W29 E30 R33 W34 Q35 L36 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 V52 A53 Y54 S55 G56 R57 K58 Q62 K63 H64 G66 R67 A68 R69 H70 G71 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 P97 K98 K99 R101 K130 T131 L135 R160 R163 N164 P166 V169 T170 A172 E174 G175 N177 Y179 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vvo G 3.22 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 T71 A73 K74 K75 I77 N79 L82 I88 R91 N123 S124 D126 R128 N132 G134 D156 K35 N39 G41 G43 E44 K46 T70 A72 K73 K74 I76 N78 L81 I87 R90 N122 S123 D125 R127 N131 G133 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvo G 3.22 BS02 NUC B 1 P2 N27 V28 W29 E30 Q66 K67 P68 A69 V70 R91 V92 T93 R95 R96 R98 P1 N26 V27 W28 E29 Q65 K66 P67 A68 V69 R90 V91 T92 R94 R95 R97 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvo I 3.22 BS01 NUC A 1 K22 P23 G24 Y25 N28 E41 S42 K45 A46 A49 R50 R52 K22 P23 G24 Y25 N28 E41 S42 K45 A46 A49 R50 R52 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vvo N 3.22 BS01 NUC A 1 K2 T3 W13 L23 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 G64 K65 K66 Q69 K70 R74 Y75 S76 Y78 G80 G81 L82 K83 R97 E100 H101 A102 K104 G105 M106 P108 G110 P111 L112 R114 F117 K118 R119 K121 P129 K2 T3 W13 L23 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 G64 K65 K66 Q69 K70 R74 Y75 S76 Y78 G80 G81 L82 K83 R97 E100 H101 A102 K104 G105 M106 P108 G110 P111 L112 R114 F117 K118 R119 K121 P129 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vvo Q 3.22 BS01 NUC A 1 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 G24 Y26 W41 Q45 Q46 A49 R56 K63 F65 I66 R67 F69 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 G24 Y26 W41 Q45 Q46 A49 R56 K63 F65 I66 R67 F69 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vvo Q 3.22 BS02 NUC B 1 R16 L17 G19 A20 R16 L17 G19 A20 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vvo S 3.22 BS02 NUC B 1 R10 R15 K19 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 I40 G45 V46 T47 S50 S52 L54 A55 K57 K59 N61 K62 T63 Y92 K93 H95 R97 R9 R14 K18 R24 F28 R29 S30 L31 K32 H33 Y35 Q37 I39 G44 V45 T46 S49 S51 L53 A54 K56 K58 N60 K61 T62 Y91 K92 H94 R96 Q5SHQ4 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 1vvo W 3.22 BS01 NUC A 1 K4 A5 I6 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 P80 K83 R84 L86 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 K4 A5 I6 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 P80 K83 R84 L86 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK 1vvo X 3.22 BS02 MG X 1 A17 K25 Y26 T27 A15 K23 Y24 T25 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vvo Z 3.22 BS01 NUC A 1 I120 I146 G147 S149 H151 E169 T170 V175 P176 I120 I146 G147 S149 H151 E169 T170 V175 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvo Z 3.22 BS02 NUC B 1 R10 K14 P15 R19 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R10 K14 P15 R19 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvo 6 3.22 BS01 NUC A 1 V5 R6 K8 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 K45 H46 V1 R2 K4 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 K41 H42 P35871 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 1vvp J 3.90 BS01 NUC A 1 R5 K7 R9 H13 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 K99 R3 K5 R7 H11 D15 S33 G34 P35 I36 P37 L38 P39 T40 R41 V42 R43 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 K97 Q5SHN7 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV 1vvq F 3.90 BS02 MG F 1 R168 N169 R163 N164 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vvq G 3.90 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 T71 A73 K74 K75 N79 F80 L82 I88 R91 R128 N130 N132 G134 R136 D156 A158 K35 N39 G41 G43 E44 K46 T70 A72 K73 K74 N78 F79 L81 I87 R90 R127 N129 N131 G133 R135 D155 A157 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvq H 3.90 BS01 NUC A 1 S2 R3 I4 G5 R59 K62 S63 G66 L67 T70 N74 F109 S110 K138 Q139 G142 Q143 R152 Y157 H158 K160 R170 S1 R2 I3 G4 R58 K61 S62 G65 L66 T69 N73 F108 S109 K137 Q138 G141 Q142 R151 Y156 H157 K159 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 1vvq P 3.90 BS02 MG P 1 T30 G34 H35 T30 G34 H35 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vvq Z 3.90 BS01 NUC A 1 I120 I146 G147 H151 E168 E169 T170 P176 I120 I146 G147 H151 E168 E169 T170 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvq 1 3.90 BS01 NUC A 1 S2 K3 K10 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 R26 G28 V30 G31 K32 K33 T34 T35 K39 R40 R41 Q42 Y43 P44 N45 Q47 R50 R52 R61 S65 H66 K69 R76 K78 K88 E93 L94 L97 L98 S1 K2 K9 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 R25 G27 V29 G30 K31 K32 T33 T34 K38 R39 R40 Q41 Y42 P43 N44 Q46 R49 R51 R60 S64 H65 K68 R75 K77 K87 E92 L93 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 1vvr C 3.90 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 K27 S154 G155 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 F186 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 K26 S153 G154 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 F185 R189 T191 Y192 G193 V194 G196 K198 P80372 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGE 1vvr H 3.90 BS01 NUC A 1 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 K88 P89 G90 R92 Y94 V97 S113 T114 S115 V129 E132 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 K88 P89 G90 R92 Y94 V97 S113 T114 S115 V129 E132 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vvr K 3.90 BS01 NUC A 1 Y20 N26 N27 T31 T33 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 N16 N17 T21 T23 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vvr M 3.90 BS01 NUC A 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 V74 N77 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 N106 A107 R108 T109 K111 R114 K115 T116 K121 K12 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 V73 N76 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 N105 A106 R107 T108 K110 R113 K114 T115 K120 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vvr M 3.90 BS03 NUC Y 1 K121 K122 K120 K121 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vvr N 3.90 BS01 NUC A 1 A2 R3 K4 A5 L6 K9 F16 K17 V18 R19 Y21 T22 R23 C27 R29 A30 R31 S32 V33 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 K8 F15 K16 V17 R18 Y20 T21 R22 C26 R28 A29 R30 S31 V32 R34 R40 I41 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 1vvr Q 3.90 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 R25 Q26 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 R81 K87 R91 R92 N94 Y95 S97 L98 S99 K100 R101 P1 K2 K3 S11 K13 M14 Q15 K16 T17 R24 Q25 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 R80 K86 R90 R91 N93 Y94 S96 L97 S98 K99 R100 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 1vvs F 3.90 BS01 NUC A 1 N29 H31 W34 E35 R38 W39 Q40 L41 K43 R44 R45 R46 G47 T48 A49 S50 T51 K52 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 W65 Q67 K68 H69 G71 R72 A73 R74 H75 G76 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 P102 K103 K104 R106 G134 K135 T136 R165 R168 N169 L170 P171 V174 T175 E179 G180 N182 Y184 R205 N24 H26 W29 E30 R33 W34 Q35 L36 K38 R39 R40 R41 G42 T43 A44 S45 T46 K47 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 W60 Q62 K63 H64 G66 R67 A68 R69 H70 G71 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 P97 K98 K99 R101 G129 K130 T131 R160 R163 N164 L165 P166 V169 T170 E174 G175 N177 Y179 R200 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vvs G 3.90 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 T71 A73 K74 K75 I77 N79 L82 I88 R91 N123 S124 R128 N132 L133 G134 R136 R153 G154 D156 K35 N39 G41 G43 E44 K46 T70 A72 K73 K74 I76 N78 L81 I87 R90 N122 S123 R127 N131 L132 G133 R135 R152 G153 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvs I 3.90 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 R33 S42 K45 A46 A49 R50 R52 K22 P23 G24 Y25 N28 Y29 R33 S42 K45 A46 A49 R50 R52 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vvs P 3.90 BS02 MG P 1 D5 L6 R7 D5 L6 R7 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vvs W 3.90 BS01 NUC A 1 A5 I6 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 K49 S53 A56 N57 N60 N61 H62 Y75 V76 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 A5 I6 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 K49 S53 A56 N57 N60 N61 H62 Y75 V76 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK 1vvs Y 3.90 BS01 NUC A 1 R2 K4 H6 K8 K9 S17 G18 K19 K21 V30 P32 Y35 I44 V45 K47 V49 V51 G58 G59 F60 H68 S70 K71 R73 R84 V85 R1 K3 H5 K7 K8 S16 G17 K18 K20 V29 P31 Y34 I43 V44 K46 V48 V50 G57 G58 F59 H67 S69 K70 R72 R83 V84 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vvs Z 3.90 BS01 NUC A 1 I146 G147 H151 E169 T170 P176 I146 G147 H151 E169 T170 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvs Z 3.90 BS02 NUC B 1 R10 P15 R19 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R10 P15 R19 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvs 0 3.90 BS01 NUC A 1 A2 H3 K4 G8 S9 T10 N12 R14 D15 S16 Q17 A18 K19 R20 K24 R25 Y26 E27 G28 Q29 A33 G34 N35 I36 R39 R41 G42 T43 F45 G54 R55 D56 F57 F60 F69 R74 L75 R77 A1 H2 K3 G7 S8 T9 N11 R13 D14 S15 Q16 A17 K18 R19 K23 R24 Y25 E26 G27 Q28 A32 G33 N34 I35 R38 R40 G41 T42 F44 G53 R54 D55 F56 F59 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vvs 1 3.90 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 R21 K25 R26 G28 V30 K32 K33 T34 T35 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 R50 R52 R61 A64 S65 H66 I67 K69 K78 K88 E93 L97 L98 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 R20 K24 R25 G27 V29 K31 K32 T33 T34 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 R49 R51 R60 A63 S64 H65 I66 K68 K77 K87 E92 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 1vvs 3 3.90 BS01 NUC A 1 K10 S11 I13 G14 K17 A21 A22 K24 A25 R29 R30 L31 Q32 P41 A42 I43 G45 N46 K49 K9 S10 I12 G13 K16 A20 A21 K23 A24 R28 R29 L30 Q31 P40 A41 I42 G44 N45 K48 Q5SHQ6 PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 1vvs 9 3.90 BS01 NUC A 1 M1 V3 R4 A5 S6 V7 K8 K15 V16 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 V3 R4 A5 S6 V7 K8 K15 V16 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 P80256 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 1vvt N 3.90 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 F16 K17 V18 R19 Y21 T22 R29 A30 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 F15 K16 V17 R18 Y20 T21 R28 A29 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 1vvu D 3.90 BS02 MG D 1 N45 Q46 R48 N44 Q45 R47 P60405 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIAR 1vvu G 3.90 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 T71 A73 K74 K75 I77 N79 F80 L82 I88 R91 R128 N132 G134 L152 R153 G154 D156 K35 N39 G41 G43 E44 K46 T70 A72 K73 K74 I76 N78 F79 L81 I87 R90 R127 N131 G133 L151 R152 G153 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvu S 3.90 BS02 NUC B 1 R15 K19 R25 F29 R30 S31 L32 K33 Y36 Q38 I40 G45 V46 T47 S50 L54 A55 K57 N61 K62 T63 Y92 K93 H95 G96 R97 R14 K18 R24 F28 R29 S30 L31 K32 Y35 Q37 I39 G44 V45 T46 S49 L53 A54 K56 N60 K61 T62 Y91 K92 H94 G95 R96 Q5SHQ4 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 1vvu X 3.90 BS01 NUC A 1 S14 E15 K16 K25 H31 T35 K36 T37 K40 N41 E44 K50 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 Y69 L70 G71 K72 R73 D75 K78 S12 E13 K14 K23 H29 T33 K34 T35 K38 N39 E42 K48 K51 N53 T54 L55 H56 R58 K60 K61 K62 R63 L64 Y67 L68 G69 K70 R71 D73 K76 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vvu Y 3.90 BS01 NUC A 1 R2 K4 H6 K8 K9 S17 G18 K19 K21 V30 P32 Y35 I44 K47 V49 V51 F60 H68 S70 K71 R73 P82 R84 V85 E91 R1 K3 H5 K7 K8 S16 G17 K18 K20 V29 P31 Y34 I43 K46 V48 V50 F59 H67 S69 K70 R72 P81 R83 V84 E90 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vvu Z 3.90 BS01 NUC A 1 Q118 I120 I146 G147 H151 E168 E169 T170 V175 Q118 I120 I146 G147 H151 E168 E169 T170 V175 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvv F 3.90 BS01 NUC A 1 R2 Y4 Y50 K54 E69 V72 N73 V90 K92 R2 Y4 Y50 K54 E69 V72 N73 V90 K92 Q5SLP8 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 1vvv O 3.90 BS01 NUC A 1 P2 K5 Q9 D21 T22 G23 T25 Q28 L31 R35 H42 H46 K48 D49 H50 H51 S52 H53 R54 G55 M58 M59 G61 Q62 R64 R65 R68 Y69 R72 P1 K4 Q8 D20 T21 G22 T24 Q27 L30 R34 H41 H45 K47 D48 H49 H50 S51 H52 R53 G54 M57 M58 G60 Q61 R63 R64 R67 Y68 R71 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 1vvv T 3.90 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 R22 R23 R25 K27 A28 K29 S31 A32 T35 L36 K38 K39 K54 I55 R57 E60 D64 K65 K68 S70 K74 A78 R79 K81 S82 R83 M85 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 R15 R16 R18 K20 A21 K22 S24 A25 T28 L29 K31 K32 K47 I48 R50 E53 D57 K58 K61 S63 K67 A71 R72 K74 S75 R76 M78 R82 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vvw G 3.90 BS01 NUC A 1 K36 N40 G42 L43 G44 E45 K47 T71 R72 A73 K74 K75 I77 N79 L82 I88 R91 D126 R128 N132 G134 G154 D156 K35 N39 G41 L42 G43 E44 K46 T70 R71 A72 K73 K74 I76 N78 L81 I87 R90 D125 R127 N131 G133 G153 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vvw H 3.90 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 G108 F109 S110 H111 K138 Q139 G142 Q143 Y157 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 G107 F108 S109 H110 K137 Q138 G141 Q142 Y156 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 1vvw S 3.90 BS02 NUC B 1 R10 R15 K19 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 I40 G45 V46 T47 S52 L54 K57 K59 N61 K62 T63 Y92 K93 H95 R97 R9 R14 K18 R24 F28 R29 S30 L31 K32 H33 Y35 Q37 I39 G44 V45 T46 S51 L53 K56 K58 N60 K61 T62 Y91 K92 H94 R96 Q5SHQ4 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 1vvw Y 3.90 BS01 NUC A 1 K4 H6 K8 S17 G18 K19 K21 V30 P32 Y35 I44 K47 V49 V51 G59 F60 H68 S70 K71 R73 R84 V85 E91 K3 H5 K7 S16 G17 K18 K20 V29 P31 Y34 I43 K46 V48 V50 G58 F59 H67 S69 K70 R72 R83 V84 E90 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vvw Z 3.90 BS01 NUC A 1 I146 G147 E169 T170 V175 P176 I146 G147 E169 T170 V175 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvw Z 3.90 BS02 NUC B 1 R10 P15 R19 Y29 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R10 P15 R19 Y29 K36 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvw 9 3.90 BS01 NUC A 1 M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 G21 R22 V23 Y24 I26 P30 K31 K33 R35 Q36 G37 M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 G21 R22 V23 Y24 I26 P30 K31 K33 R35 Q36 G37 P80256 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 1vvx B 3.92 BS01 NUC A 1 P26 R96 L98 G99 G100 T103 N104 T107 R111 K133 R144 Y148 I172 E176 K179 P23 R93 L95 G96 G97 T100 N101 T104 R108 K130 R141 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vvx E 3.92 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 K47 A48 P49 K57 Y61 G85 A86 K92 A95 T98 I101 A102 L119 T120 K121 E122 S125 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 K43 A44 P45 K53 Y57 G81 A82 K88 A91 T94 I97 A98 L115 T116 K117 E118 S121 N123 I125 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 1vvx L 3.92 BS01 NUC A 1 P5 T6 N8 Q9 R12 R15 E16 K17 K20 K21 S22 K28 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 T61 Y69 P71 G72 E73 R86 G87 V90 K91 D92 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 R8 R11 E12 K13 K16 K17 S18 K24 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 P67 G68 E69 R82 G83 V86 K87 D88 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 1vvx M 3.92 BS03 MG M 1 T20 Y21 I22 I25 T19 Y20 I21 I24 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vvy R 3.92 BS02 MG R 1 R2 H3 R2 H3 Q9Z9H5 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 1vvy Z 3.92 BS01 NUC A 1 I120 I146 G147 H151 E168 E169 T170 A173 I120 I146 G147 H151 E168 E169 T170 A173 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvy Z 3.92 BS02 NUC B 1 R10 K14 P15 R19 G26 Y29 N30 N34 K36 R72 Q73 N75 R79 E84 H85 F89 R10 K14 P15 R19 G26 Y29 N30 N34 K36 R72 Q73 N75 R79 E84 H85 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vvy 0 3.92 BS02 NUC B 1 R72 G73 R74 R71 G72 R73 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vvz K 3.92 BS01 NUC A 1 Y20 H22 N26 N27 T31 G37 N38 P39 W42 S44 G46 G52 S53 K55 R85 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 H12 N16 N17 T21 G27 N28 P29 W32 S34 G36 G42 S43 K45 R75 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vvz L 3.92 BS01 NUC A 1 P5 T6 N8 L10 R12 R15 E16 K17 K20 K21 K28 G29 A30 P31 F32 R33 R34 K46 K47 P48 N49 S50 L52 R53 K54 K57 T61 Y69 P71 G72 E73 G74 R86 G87 V90 K91 D92 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 L6 R8 R11 E12 K13 K16 K17 K24 G25 A26 P27 F28 R29 R30 K42 K43 P44 N45 S46 L48 R49 K50 K53 T57 Y65 P67 G68 E69 G70 R82 G83 V86 K87 D88 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 1vvz T 3.92 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 R25 N26 K27 A28 K29 S31 A32 K34 T35 L36 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 A78 R79 K81 S82 R83 M85 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 R18 N19 K20 A21 K22 S24 A25 K27 T28 L29 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 A71 R72 K74 S75 R76 M78 R82 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vw0 G 3.92 BS01 NUC A 1 K36 N40 G42 G44 E45 T71 A73 K74 K75 I77 L82 I88 R91 N123 R128 N130 N132 G154 D156 K35 N39 G41 G43 E44 T70 A72 K73 K74 I76 L81 I87 R90 N122 R127 N129 N131 G153 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vw0 I 3.92 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 S42 K45 A46 R50 K22 P23 G24 Y25 N28 Y29 S42 K45 A46 R50 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vw0 N 3.92 BS01 NUC A 1 K2 T3 V5 W13 L23 G24 R25 T28 K29 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 P79 G80 G81 K83 K89 R97 E100 H101 A102 K104 G105 M106 P108 G110 P111 L112 R114 K118 R119 P129 Q131 K2 T3 V5 W13 L23 G24 R25 T28 K29 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 P79 G80 G81 K83 K89 R97 E100 H101 A102 K104 G105 M106 P108 G110 P111 L112 R114 K118 R119 P129 Q131 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vw0 Z 3.92 BS01 NUC A 1 R112 Q118 I120 I146 G147 D148 E169 T170 V175 P176 R112 Q118 I120 I146 G147 D148 E169 T170 V175 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vw0 Z 3.92 BS02 NUC B 1 R10 P15 R19 G26 V27 Y29 N30 R31 N34 K36 R72 Q73 R79 E84 H85 D87 R10 P15 R19 G26 V27 Y29 N30 R31 N34 K36 R72 Q73 R79 E84 H85 D87 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vw0 0 3.92 BS01 NUC A 1 A2 H3 K4 G8 S9 T10 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 G28 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 F45 G54 R55 D56 F57 T58 F60 L62 F69 R74 L75 R77 A1 H2 K3 G7 S8 T9 N11 R13 D14 S15 Q16 A17 K18 R19 V22 K23 R24 Y25 E26 G27 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 F44 G53 R54 D55 F56 T57 F59 L61 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vw0 0 3.92 BS02 NUC B 1 D71 R72 G73 R74 L75 D70 R71 G72 R73 L74 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vw0 2 3.92 BS01 NUC A 1 E5 R7 L10 R14 K29 Q46 N47 H48 I50 R51 K54 R55 A58 R59 T62 N65 E66 R69 E2 R4 L7 R11 K26 Q43 N44 H45 I47 R48 K51 R52 A55 R56 T59 N62 E63 R66 Q5SHP6 SEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 1vw0 6 3.92 BS01 NUC A 1 V5 R6 K8 R19 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 W42 K45 H46 V1 R2 K4 R15 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 W38 K41 H42 P35871 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 1vx8 D 2.94 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K85 V112 S113 R115 Q116 Q119 R122 H123 H125 R131 R132 V133 D134 L135 S137 Y138 R141 K151 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K84 V111 S112 R114 Q115 Q118 R121 H122 H124 R130 R131 V132 D133 L134 S136 Y137 R140 K150 L154 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 1vx8 F 2.94 BS01 NUC A 1 R2 Y4 Y50 K54 E69 V72 N73 R77 R80 R87 V90 V91 K92 R2 Y4 Y50 K54 E69 V72 N73 R77 R80 R87 V90 V91 K92 Q5SLP8 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 1vx8 K 2.94 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 D36 G37 N38 P39 W42 S44 G46 G52 S53 K55 R85 V114 P115 H116 N117 G118 C119 R120 K122 K123 K124 Y10 H12 N16 N17 I19 T21 D26 G27 N28 P29 W32 S34 G36 G42 S43 K45 R75 V104 P105 H106 N107 G108 C109 R110 K112 K113 K114 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vx8 M 2.94 BS03 MG M 1 T20 Y21 I22 Y23 I25 T19 Y20 I21 Y22 I24 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 1vx8 O 2.94 BS01 NUC A 1 P2 K5 K8 Q9 I12 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 H53 R54 G55 M58 M59 G61 R64 R65 R68 Y69 R72 P1 K4 K7 Q8 I11 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 H52 R53 G54 M57 M58 G60 R63 R64 R67 Y68 R71 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 1vx8 P 2.94 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 K27 R28 G30 K31 Y32 K35 Y38 P41 R42 K43 T44 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 K27 R28 G30 K31 Y32 K35 Y38 P41 R42 K43 T44 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 1vx8 R 2.94 BS01 NUC A 1 K49 I50 P52 R53 R54 K61 Q63 R64 K68 K71 R72 R74 I75 F81 T82 K31 I32 P34 R35 R36 K43 Q45 R46 K50 K53 R54 R56 I57 F63 T64 Q5SLQ0 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 1vx9 G 2.94 BS01 NUC A 1 K36 N40 G42 L43 G44 E45 T71 R72 A73 K74 N79 F80 L82 I88 R91 S124 D126 R128 N130 N132 L133 G134 L135 G154 M155 D156 A158 K35 N39 G41 L42 G43 E44 T70 R71 A72 K73 N78 F79 L81 I87 R90 S123 D125 R127 N129 N131 L132 G133 L134 G153 M154 D155 A157 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vx9 N 2.94 BS01 NUC A 1 K2 T3 V5 W13 L23 G24 R25 T28 K29 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 T73 R74 Y75 S76 Y78 P79 G80 G81 L82 K89 H94 R97 E100 H101 A102 G105 M106 P108 K109 P111 L112 R114 K118 K121 P129 Q131 K2 T3 V5 W13 L23 G24 R25 T28 K29 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 T73 R74 Y75 S76 Y78 P79 G80 G81 L82 K89 H94 R97 E100 H101 A102 G105 M106 P108 K109 P111 L112 R114 K118 K121 P129 Q131 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vx9 O 2.94 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 Q5SHP8 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 1vx9 P 2.94 BS01 NUC A 1 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 G20 R21 G22 P23 G24 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 G20 R21 G22 P23 G24 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 Q5SHQ7 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 1vx9 Q 2.94 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 T21 K22 G23 Y26 W41 Q46 A49 V52 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 T21 K22 G23 Y26 W41 Q46 A49 V52 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vx9 X 2.94 BS01 NUC A 1 S14 E15 K16 K25 H31 K33 T35 K36 T37 E38 N41 E44 K53 N55 T56 L57 H58 R60 K62 K64 R65 L66 Y69 L70 G71 K72 R73 P74 D75 K78 I80 S12 E13 K14 K23 H29 K31 T33 K34 T35 E36 N39 E42 K51 N53 T54 L55 H56 R58 K60 K62 R63 L64 Y67 L68 G69 K70 R71 P72 D73 K76 I78 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vx9 Y 2.94 BS01 NUC A 1 R2 K4 H6 K8 K9 S17 G18 K19 V30 P32 K34 Y35 I44 V45 K46 K47 A48 V49 V51 G58 G59 F60 H68 S70 K71 R73 R84 V85 E91 R1 K3 H5 K7 K8 S16 G17 K18 V29 P31 K33 Y34 I43 V44 K45 K46 A47 V48 V50 G57 G58 F59 H67 S69 K70 R72 R83 V84 E90 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vx9 Z 2.94 BS01 NUC A 1 I120 I146 G147 S149 H151 E168 E169 T170 I120 I146 G147 S149 H151 E168 E169 T170 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vx9 Z 2.94 BS02 NUC B 1 R10 P15 R19 Y29 N30 N34 R72 Q73 N75 R79 E84 H85 D87 F89 R10 P15 R19 Y29 N30 N34 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vx9 2 2.94 BS01 NUC A 1 S4 E5 R7 R14 K29 Q46 N47 H48 I50 R51 K54 R55 A58 R59 L61 T62 N65 E66 R69 S1 E2 R4 R11 K26 Q43 N44 H45 I47 R48 K51 R52 A55 R56 L58 T59 N62 E63 R66 Q5SHP6 SEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 1vx9 6 2.94 BS01 NUC A 1 V5 R6 K8 Y21 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 K45 H46 K53 V1 R2 K4 Y17 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 K41 H42 K49 P35871 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 1vx9 7 2.94 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 R23 P25 G26 G27 R28 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41 R47 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 R23 P25 G26 G27 R28 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41 R47 K48 R49 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 1vx9 9 2.94 BS01 NUC A 1 M1 R4 A5 S6 V7 K8 R9 I10 K15 V16 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 R4 A5 S6 V7 K8 R9 I10 K15 V16 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 P80256 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 1vxi B 2.94 BS01 NUC A 1 K22 W24 P26 R96 G99 G100 T103 N104 I108 R111 K133 R144 Y148 I172 E176 K179 K19 W21 P23 R93 G96 G97 T100 N101 I105 R108 K130 R141 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vxi C 2.94 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 K27 R127 S154 G155 R156 E161 Q162 A163 W167 R172 V173 L175 H176 T177 L178 R179 F186 L188 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 K26 R126 S153 G154 R155 E160 Q161 A162 W166 R171 V172 L174 H175 T176 L177 R178 F185 L187 R189 T191 Y192 G193 V194 G196 K198 P80372 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGE 1vxi D 2.94 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 R57 R59 K61 Q62 R65 R66 E72 R73 Q74 R76 N77 K86 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 R56 R58 K60 Q61 R64 R65 E71 R72 Q73 R75 N76 K85 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 L154 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 1vxi E 2.94 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y60 Y61 F84 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y56 Y57 F80 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 1vxi H 2.94 BS01 NUC A 1 M1 L2 T3 P5 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 G128 V129 G130 E132 M1 L2 T3 P5 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 G128 V129 G130 E132 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vxi K 2.94 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 D36 G37 N38 P39 I40 W42 S44 G46 G52 S53 K55 Y75 R85 P113 V114 H116 N117 G118 C119 R120 K122 K123 K124 Y10 H12 N16 N17 I19 T21 D26 G27 N28 P29 I30 W32 S34 G36 G42 S43 K45 Y65 R75 P103 V104 H106 N107 G108 C109 R110 K112 K113 K114 P80376 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 1vxi L 2.94 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K17 K20 K21 K23 V24 K28 G29 P31 F32 R33 R34 K46 K47 P48 N49 S50 A51 L52 R53 K54 K57 T61 Y69 P71 G72 E73 G74 R86 R89 V90 K91 D92 P94 G95 R97 V101 V104 R113 K114 K115 S116 R117 S118 K119 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K13 K16 K17 K19 V20 K24 G25 P27 F28 R29 R30 K42 K43 P44 N45 S46 A47 L48 R49 K50 K53 T57 Y65 P67 G68 E69 G70 R82 R85 V86 K87 D88 P90 G91 R93 V97 V100 R109 K110 K111 S112 R113 S114 K115 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 1vxi N 2.94 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 F16 K17 V18 R19 Y21 T22 C27 R29 R31 S32 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 F15 K16 V17 R18 Y20 T21 C26 R28 R30 S31 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 1vxi O 2.94 BS01 NUC A 1 P2 K5 K8 Q9 I12 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 M59 G61 Q62 R64 R65 L66 R68 Y69 R72 P1 K4 K7 Q8 I11 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 M58 G60 Q61 R63 R64 L65 R67 Y68 R71 Q5SJ76 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 1vxi T 2.94 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 R22 R23 N26 K27 A28 K29 S31 A32 T35 L36 K39 E51 I55 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 R15 R16 N19 K20 A21 K22 S24 A25 T28 L29 K32 E44 I48 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R82 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 1vxj F 2.94 BS01 NUC A 1 N29 H31 L32 W34 E35 R38 Q40 L41 R44 R45 R46 T48 A49 S50 T51 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 W65 Q67 K68 H69 G71 R72 A73 R74 H75 G76 I78 P81 I82 F83 V84 G85 V88 V89 F90 G91 P92 P94 R95 Y99 T100 L101 P102 K103 K104 V105 R106 K108 K135 T136 L140 R165 R168 N169 L170 P171 V174 T175 A177 E179 G180 N182 Y184 N24 H26 L27 W29 E30 R33 Q35 L36 R39 R40 R41 T43 A44 S45 T46 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 W60 Q62 K63 H64 G66 R67 A68 R69 H70 G71 I73 P76 I77 F78 V79 G80 V83 V84 F85 G86 P87 P89 R90 Y94 T95 L96 P97 K98 K99 V100 R101 K103 K130 T131 L135 R160 R163 N164 L165 P166 V169 T170 A172 E174 G175 N177 Y179 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vxj G 2.94 BS01 NUC A 1 K36 V38 N40 G42 L43 G44 E45 T71 R72 A73 K74 K75 I77 N79 F80 L82 I88 G89 R91 S124 D126 R128 N130 N132 L133 G134 L135 G154 M155 D156 A158 V160 K35 V37 N39 G41 L42 G43 E44 T70 R71 A72 K73 K74 I76 N78 F79 L81 I87 G88 R90 S123 D125 R127 N129 N131 L132 G133 L134 G153 M154 D155 A157 V159 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vxj H 2.94 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 N74 K85 G108 F109 S110 H111 K138 Q139 G142 Q143 A146 R152 Y157 H158 K160 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 N73 K84 G107 F108 S109 H110 K137 Q138 G141 Q142 A145 R151 Y156 H157 K159 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 1vxj I 2.94 BS01 NUC A 1 N11 K22 G24 Y25 N28 Y29 S42 K45 A46 A49 R50 R52 N11 K22 G24 Y25 N28 Y29 S42 K45 A46 A49 R50 R52 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vxj N 2.94 BS01 NUC A 1 K2 T3 V5 W13 L23 G24 R25 T28 K29 A31 R35 K37 P44 N45 F51 T63 K65 K66 Q69 K70 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 P108 G110 P111 L112 R114 K118 R119 P129 K2 T3 V5 W13 L23 G24 R25 T28 K29 A31 R35 K37 P44 N45 F51 T63 K65 K66 Q69 K70 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 P108 G110 P111 L112 R114 K118 R119 P129 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vxj Q 2.94 BS01 NUC A 1 P4 R5 R6 K8 Y9 R10 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 Y26 F29 W41 Q46 A49 R56 K63 F65 R67 F69 D71 Y74 K76 K77 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 R10 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 Y26 F29 W41 Q46 A49 R56 K63 F65 R67 F69 D71 Y74 K76 K77 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vxj W 2.94 BS01 NUC A 1 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 D77 E78 P80 L82 K83 R84 P87 R88 A89 R90 G91 R92 D94 I96 K97 K98 R99 H102 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 D77 E78 P80 L82 K83 R84 P87 R88 A89 R90 G91 R92 D94 I96 K97 K98 R99 H102 Q5SHP3 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK 1vxj X 2.94 BS01 NUC A 1 S14 E15 K16 K25 H31 K33 T35 K36 T37 K40 N41 E44 K50 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 Y69 L70 G71 K72 R73 P74 D75 K77 K78 S12 E13 K14 K23 H29 K31 T33 K34 T35 K38 N39 E42 K48 K51 N53 T54 L55 H56 R58 K60 K61 K62 R63 L64 Y67 L68 G69 K70 R71 P72 D73 K75 K76 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vxj X 2.94 BS02 MG X 1 A17 G20 F21 K25 Y26 T27 A15 G18 F19 K23 Y24 T25 Q5SHP0 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 1vxj Y 2.94 BS01 NUC A 1 R2 H6 K8 K9 S17 G18 K19 V30 P32 K34 Y35 I44 V45 K46 K47 A48 V49 V51 G58 G59 F60 H68 S70 K71 R73 P82 R84 V85 R1 H5 K7 K8 S16 G17 K18 V29 P31 K33 Y34 I43 V44 K45 K46 A47 V48 V50 G57 G58 F59 H67 S69 K70 R72 P81 R83 V84 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vxj Z 2.94 BS01 NUC A 1 I120 I146 G147 S149 H151 E169 T170 P176 I120 I146 G147 S149 H151 E169 T170 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxj Z 2.94 BS02 NUC B 1 R10 K14 P15 R19 G26 V27 Y29 N30 N34 R72 Q73 N75 R79 E84 H85 D87 F89 R10 K14 P15 R19 G26 V27 Y29 N30 N34 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxj 0 2.94 BS02 NUC B 1 D71 R72 G73 R74 D70 R71 G72 R73 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vxj 0 2.94 BS03 NUC a 1 A2 H3 A1 H2 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 1vxj 5 2.94 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 D17 A18 R19 R20 S21 H22 H23 T29 V31 P32 H43 Y51 Y52 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 D16 A17 R18 R19 S20 H21 H22 T28 V30 P31 H42 Y50 Y51 P80339 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 1vxk B 3.48 BS01 NUC A 1 K22 R96 L98 G99 G100 T103 N104 T107 R111 K133 Y148 I172 E176 K179 K19 R93 L95 G96 G97 T100 N101 T104 R108 K130 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vxk E 3.48 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 P49 K57 Y60 Y61 F84 G85 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 P45 K53 Y56 Y57 F80 G81 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 1vxl N 3.48 BS01 NUC A 1 K2 T3 W13 L23 G24 R25 T28 K29 T32 R35 K37 P44 N45 F51 T63 K65 K66 Q69 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 K89 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 F117 K118 K121 P129 Q131 K2 T3 W13 L23 G24 R25 T28 K29 T32 R35 K37 P44 N45 F51 T63 K65 K66 Q69 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 K89 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 F117 K118 K121 P129 Q131 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 1vxl Z 3.48 BS01 NUC A 1 I146 G147 H151 E168 E169 T170 P176 I146 G147 H151 E168 E169 T170 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxl Z 3.48 BS02 NUC B 1 R10 P15 R19 Y29 N34 K36 R72 Q73 N75 E84 H85 D87 F89 R10 P15 R19 Y29 N34 K36 R72 Q73 N75 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxl 8 3.48 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K11 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 Q35 S37 G38 K39 I41 R42 Q43 R46 F48 V49 K52 L61 L62 Y64 E65 P1 K2 M3 K4 T5 H6 K7 K10 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 Q34 S36 G37 K38 I40 R41 Q42 R45 F47 V48 K51 L60 L61 Y63 E64 Q5SKU1 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 1vxm H 3.48 BS01 NUC A 1 M1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 K21 S29 R30 F31 K56 P57 K88 P89 G90 R92 Y94 V97 S113 T114 S115 V129 E132 M1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 K21 S29 R30 F31 K56 P57 K88 P89 G90 R92 Y94 V97 S113 T114 S115 V129 E132 Q5SHQ2 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 1vxm L 3.48 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K17 K20 K21 S22 G29 A30 P31 F32 R33 R34 K46 K47 P48 N49 S50 A51 L52 R53 K54 K57 Y69 P71 G72 E73 G74 R86 G87 R89 V90 K91 D92 P94 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K13 K16 K17 S18 G25 A26 P27 F28 R29 R30 K42 K43 P44 N45 S46 A47 L48 R49 K50 K53 Y65 P67 G68 E69 G70 R82 G83 R85 V86 K87 D88 P90 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 1vxn G 3.48 BS01 NUC A 1 K36 N40 G42 L43 G44 E45 K47 T71 R72 A73 K74 K75 I77 N79 F80 L82 I88 R91 S124 R128 N130 N132 L133 G134 G154 D156 K35 N39 G41 L42 G43 E44 K46 T70 R71 A72 K73 K74 I76 N78 F79 L81 I87 R90 S123 R127 N129 N131 L132 G133 G153 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vxn Z 3.48 BS01 NUC A 1 I146 G147 H151 E169 T170 V175 P176 I146 G147 H151 E169 T170 V175 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxn Z 3.48 BS02 NUC B 1 R10 K14 P15 R19 V27 Y29 N30 N34 K36 R72 Q73 N75 R79 H85 D87 F89 R10 K14 P15 R19 V27 Y29 N30 N34 K36 R72 Q73 N75 R79 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxp B 3.14 BS01 NUC A 1 R96 G99 G100 T103 N104 T107 R111 K133 R144 Y148 I172 E176 K179 R93 G96 G97 T100 N101 T104 R108 K130 R141 Y145 I169 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 1vxp D 3.14 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 R59 K61 Q62 R66 E72 R73 Q74 N77 K85 K86 G87 S113 R115 Q116 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 K151 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 R58 K60 Q61 R65 E71 R72 Q73 N76 K84 K85 G86 S112 R114 Q115 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 K150 L154 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 1vxq F 3.14 BS01 NUC A 1 N29 H31 W34 E35 R38 Q40 L41 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 V57 A58 Y59 S60 G61 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 P102 K103 K104 V105 R106 K108 K135 T136 R165 N169 V174 T175 E179 G180 N182 Y184 N24 H26 W29 E30 R33 Q35 L36 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 V52 A53 Y54 S55 G56 R57 K58 Q62 K63 H64 G66 R67 A68 R69 H70 G71 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 P97 K98 K99 V100 R101 K103 K130 T131 R160 N164 V169 T170 E174 G175 N177 Y179 Q5SHN9 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 1vxq G 3.14 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 T71 A73 K74 K75 I77 N79 F80 L82 I88 R91 R128 N132 G134 D156 K35 N39 G41 G43 E44 K46 T70 A72 K73 K74 I76 N78 F79 L81 I87 R90 R127 N131 G133 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vxq I 3.14 BS01 NUC A 1 K22 P23 G24 Y25 R27 N28 Y29 S42 K45 A46 R50 R52 K56 K22 P23 G24 Y25 R27 N28 Y29 S42 K45 A46 R50 R52 K56 Q5SLQ1 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 1vxq Y 3.14 BS01 NUC A 1 R2 K4 H6 K8 K9 S17 G18 K19 K21 P32 Y35 I44 K47 V49 V51 F60 H68 S70 K71 R73 R84 V85 R1 K3 H5 K7 K8 S16 G17 K18 K20 P31 Y34 I43 K46 V48 V50 F59 H67 S69 K70 R72 R83 V84 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 1vxq Z 3.14 BS01 NUC A 1 I120 I146 G147 H151 E168 E169 T170 I120 I146 G147 H151 E168 E169 T170 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxt G 3.14 BS01 NUC A 1 K36 N40 G42 L43 G44 E45 K47 T71 R72 A73 K74 K75 I77 N79 F80 L82 I88 R91 S124 R128 N132 D156 K35 N39 G41 L42 G43 E44 K46 T70 R71 A72 K73 K74 I76 N78 F79 L81 I87 R90 S123 R127 N131 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 1vxt Q 3.14 BS01 NUC A 1 P4 R5 R6 K8 Y9 R10 K11 Q13 R14 G15 R16 K18 T21 K22 G23 G24 Y26 W41 Q45 Q46 A49 V52 R56 K63 F65 R67 F69 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 R10 K11 Q13 R14 G15 R16 K18 T21 K22 G23 G24 Y26 W41 Q45 Q46 A49 V52 R56 K63 F65 R67 F69 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 1vxt Z 3.14 BS01 NUC A 1 I120 I146 G147 H151 E169 T170 V175 P176 I120 I146 G147 H151 E169 T170 V175 P176 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 1vxt 2 3.14 BS01 NUC A 1 S4 E5 R7 L10 R14 K29 Q46 N47 H48 I50 R55 A58 R59 L61 T62 N65 E66 R69 S1 E2 R4 L7 R11 K26 Q43 N44 H45 I47 R52 A55 R56 L58 T59 N62 E63 R66 Q5SHP6 SEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 1vxw A 6.20 BS01 NUC g 1 V29 Q30 H32 R101 P104 G105 T108 N109 Q131 Y138 V28 Q29 H31 R100 P103 G104 T107 N108 Q130 Y137 P32905 25043550 SLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDP 1vxw B 6.20 BS01 NUC g 1 V21 P23 K27 V65 V114 R115 K116 W117 Q118 T119 E122 R136 F138 N148 Q149 V150 K151 H153 Q157 S158 S159 H160 R162 R165 K202 D203 I204 F205 V2 P4 K8 V46 V95 R96 K97 W98 Q99 T100 E103 R117 F119 N129 Q130 V131 K132 H134 Q138 S139 S140 H141 R143 R146 K183 D184 I185 F186 P33442 25043550 VVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHG 1vxw C 6.20 BS01 NUC g 1 Q87 K88 Q89 T90 R91 A92 G93 R95 R97 K99 T159 K161 G163 S164 R168 I170 V179 A180 S181 Y197 T198 Q199 N201 K203 T204 R205 T206 L207 E208 N209 Q54 K55 Q56 T57 R58 A59 G60 R62 R64 K66 T126 K128 G130 S131 R135 I137 V146 A147 S148 Y164 T165 Q166 N168 K170 T171 R172 T173 L174 E175 N176 P25443 25043550 GWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLLPGLQDEVMNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIPIRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPAVKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAIGNTYGFLTPNLWAEQPLPVSPLDIYSDEASAQ 1vxw D 6.20 BS01 NUC g 1 L4 I5 S6 K7 R9 S139 G140 R143 R146 K151 L157 I158 H159 S160 G161 Q162 P163 H174 L176 V181 K185 P203 D204 L2 I3 S4 K5 R7 S137 G138 R141 R144 K149 L155 I156 H157 S158 G159 Q160 P161 H172 L174 V179 K183 P201 D202 P05750 25043550 ALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPILAPSVKDY 1vxw E 6.20 BS01 NUC g 1 A2 R3 G4 P5 K6 K7 H8 K10 R11 L12 H16 L19 D21 K22 C26 Y27 P29 R30 A33 G34 P35 K37 L38 R49 N57 M66 R68 K75 R77 Y82 K106 R108 K128 Q130 L131 G132 K133 K134 Y138 V140 R145 T146 R148 K155 G186 R187 N188 H197 H201 D202 F205 V219 R221 N224 I248 R255 L261 A1 R2 G3 P4 K5 K6 H7 K9 R10 L11 H15 L18 D20 K21 C25 Y26 P28 R29 A32 G33 P34 K36 L37 R48 N56 M65 R67 K74 R76 Y81 K105 R107 K127 Q129 L130 G131 K132 K133 Y137 V139 R144 T145 R147 K154 G185 R186 N187 H196 H200 D201 F204 V218 R220 N223 I247 R254 L260 P0CX35 25043550 ARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL 1vxw F 6.20 BS01 NUC g 1 H72 A74 A78 K80 R81 K84 N95 L97 M98 M99 N100 G101 R102 N103 N104 G105 K106 K107 K109 R112 I113 R166 N169 F184 R185 N186 I187 K188 I190 H53 A55 A59 K61 R62 K65 N76 L78 M79 M80 N81 G82 R83 N84 N85 G86 K87 K88 K90 R93 I94 R147 N150 F165 R166 N167 I168 K169 I171 P26783 25043550 FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIFVAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLDIINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVNQAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR 1vxw F 6.20 BS02 NUC h 1 G152 G153 A154 G133 G134 A135 P26783 25043550 FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIFVAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLDIINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVNQAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR 1vxw G 6.20 BS01 NUC g 1 K2 N4 Q13 T15 K51 S53 N56 D57 Q59 G60 F61 Q65 G66 L75 C83 R85 R87 R88 G90 E91 R92 K93 R94 K95 V108 K131 R132 L133 G134 P135 K136 R137 N139 N140 K143 F144 K149 R154 R160 V162 K164 K171 A172 P173 K174 I175 Q176 R177 L178 V179 Q182 R183 L184 Q185 R186 K187 R188 H189 Q190 R191 A192 K194 V195 N197 A198 Q201 R202 L216 K220 K2 N4 Q13 T15 K51 S53 N56 D57 Q59 G60 F61 Q65 G66 L75 C83 R85 R87 R88 G90 E91 R92 K93 R94 K95 V108 K131 R132 L133 G134 P135 K136 R137 N139 N140 K143 F144 K149 R154 R160 V162 K164 K171 A172 P173 K174 I175 Q176 R177 L178 V179 Q182 R183 L184 Q185 R186 K187 R188 H189 Q190 R191 A192 K194 V195 N197 A198 Q201 R202 L216 K220 P0CX37 25043550 MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEI 1vxw H 6.20 BS01 NUC g 1 P63 V64 P65 E95 R96 R97 I98 P100 K101 R104 T105 S106 R107 Q108 Q110 K111 R112 R114 S115 R116 T117 L118 T119 H122 K148 T177 K179 P60 V61 P62 E92 R93 R94 I95 P97 K98 R101 T102 S103 R104 Q105 Q107 K108 R109 R111 S112 R113 T114 L115 T116 H119 K145 T174 K176 P26786 25043550 PQAKILSQAPTELELQVAQAFVELENSSPELKAELRPLQFKSIREIDVAGGKKALAIFVPVPSLAGFHKVQTKLTRELEKKFQDRHVIFLAERRILPKPSRTSRQVQKRPRSRTLTAVHDKILEDLVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPS 1vxw I 6.20 BS01 NUC g 1 G2 I3 R5 D6 R8 H9 K10 R11 A13 T14 A16 K17 R18 A19 R22 K23 K24 R25 K26 F27 L29 R31 Q32 P33 K41 R42 I43 H44 R47 R49 G50 K54 R56 L58 R59 N64 I72 S73 K74 S86 K98 A99 K137 N138 A139 R141 K142 S170 S171 R172 P173 Q175 R178 D180 G1 I2 R4 D5 R7 H8 K9 R10 A12 T13 A15 K16 R17 A18 R21 K22 K23 R24 K25 F26 L28 R30 Q31 P32 K40 R41 I42 H43 R46 R48 G49 K53 R55 L57 R58 N63 I71 S72 K73 S85 K97 A98 K125 N126 A127 R129 K130 S158 S159 R160 P161 Q163 R166 D168 P0CX39 25043550 GISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK 1vxw J 6.20 BS01 NUC g 1 P2 R3 P5 R6 T7 Y8 S9 K10 T11 Y12 T14 P15 K16 R17 P18 Y19 S21 K37 N38 K39 K40 E41 R44 S50 R54 R57 F71 E72 A75 R79 R82 V83 S121 H123 H124 V127 T130 Q131 R132 H133 Q139 V141 I143 P144 S145 F146 M147 R149 S162 P163 R168 G170 R171 V172 A173 R175 P1 R2 P4 R5 T6 Y7 S8 K9 T10 Y11 T13 P14 K15 R16 P17 Y18 S20 K36 N37 K38 K39 E40 R43 S49 R53 R56 F70 E71 A74 R78 R81 V82 S120 H122 H123 V126 T129 Q130 R131 H132 Q138 V140 I142 P143 S144 F145 M146 R148 S161 P162 R167 G169 R170 V171 A172 R174 O13516 25043550 PRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGE 1vxw K 6.20 BS01 NUC g 1 M1 L2 M3 R8 K44 S48 S51 K52 F59 Y64 M1 L2 M3 R8 K44 S48 S51 K52 F59 Y64 Q08745 25043550 MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERN 1vxw L 6.20 BS01 NUC g 1 E10 R11 Q14 P17 H18 F20 K26 S28 W34 K36 N37 A38 G39 L40 K43 S65 I66 R67 K69 S77 K79 M80 H81 T83 Y90 H92 Y93 P95 K96 Y97 Y100 K102 R103 H104 N106 Q127 R129 P130 I131 S132 K133 T134 F137 E9 R10 Q13 P16 H17 F19 K25 S27 W33 K35 N36 A37 G38 L39 K42 S64 I65 R66 K68 S76 K78 M79 H80 T82 Y89 H91 Y92 P94 K95 Y96 Y99 K101 R102 H103 N105 Q126 R128 P129 I130 S131 K132 T133 F136 P0CX47 25043550 STELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF 1vxw M 6.20 BS01 NUC g 1 R43 G44 L45 R46 T67 L103 K114 V116 G117 A118 R24 G25 L26 R27 T48 L84 K95 V97 G98 A99 P48589 25043550 AEVTIEDALKVVLRTALVHDGLARGLRESTKALTRGEALLVVLVSSVTEANIIKLVEGLANDPENKVPLIKVADAKQLGEWAGLGKIDREGNARKVVGASVVVVKNWGAETDELSMIMEHFSQQ 1vxw N 6.20 BS01 NUC g 1 G2 R3 M4 H5 K9 G10 I11 S12 S13 S14 A15 I16 P17 R20 S48 Q49 Q62 A63 R64 N69 K70 I71 M72 R73 D87 Y90 L91 K94 V98 H101 R104 N105 K107 D108 K109 K112 F113 R114 I116 L117 I118 S120 R121 R124 L125 R127 Y128 G1 R2 M3 H4 K8 G9 I10 S11 S12 S13 A14 I15 P16 R19 S47 Q48 Q61 A62 R63 N68 K69 I70 M71 R72 D86 Y89 L90 K93 V97 H100 R103 N104 K106 D107 K108 K111 F112 R113 I115 L116 I117 S119 R120 R123 L124 R126 Y127 P05756 25043550 GRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN 1vxw O 6.20 BS01 NUC g 1 R18 Y20 N24 D25 F27 H29 S34 G35 K36 T38 R41 T43 G45 M46 K49 A50 D51 R52 E54 P120 V121 P122 S123 D124 S125 R127 K128 G131 R132 R133 R135 R136 L137 R8 Y10 N14 D15 F17 H19 S24 G25 K26 T28 R31 T33 G35 M36 K39 A40 D41 R42 E44 P110 V111 P112 S113 D114 S115 R117 K118 G121 R122 R123 R125 R126 L127 P06367 25043550 SQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL 1vxw P 6.20 BS01 NUC g 1 R18 P38 A39 R40 R42 R43 R44 R47 A54 G55 K58 K59 R77 H79 R81 N82 Y97 N98 G99 K100 F102 Y115 G117 E118 T122 V126 R127 H128 R11 P31 A32 R33 R35 R36 R37 R40 A47 G48 K51 K52 R70 H72 R74 N75 Y90 N91 G92 K93 F95 Y108 G110 E111 T115 V119 R120 H121 Q01855 25043550 KKRVFKTHSYRGVDLEKLLEMSTEDFVKLAPARVRRRFARGMTSKPAGFMKKLRAAKLAAPENEKPAPVRTHMRNMIIVPEMIGSVVGIYNGKAFNQVEIRPEMLGHYLGEFSITYTPVRHGRA 1vxw Q 6.20 BS01 NUC g 1 Q8 T9 F10 K12 K14 T17 V19 H21 K23 L28 K30 R66 R68 G72 G73 H74 V75 S76 I118 A119 S121 R122 R123 P124 E125 P126 K127 K128 F129 G130 G133 A134 R135 S136 R137 F138 Q139 K140 S141 Y142 R143 Q6 T7 F8 K10 K12 T15 V17 H19 K21 L26 K28 R64 R66 G70 G71 H72 V73 S74 I116 A117 S119 R120 R121 P122 E123 P124 K125 K126 F127 G128 G131 A132 R133 S134 R135 F136 Q137 K138 S139 Y140 R141 P0CX51 25043550 AVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR 1vxw R 6.20 BS01 NUC g 1 G2 R3 V4 R5 T6 K7 K10 F28 K32 S43 K44 R45 L46 R47 N48 K49 G52 R60 R67 G1 R2 V3 R4 T5 K6 K9 F27 K31 S42 K43 R44 L45 R46 N47 K48 G51 R59 R66 P02407 25043550 GRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSA 1vxw S 6.20 BS01 NUC g 1 I26 K27 Y30 I35 K36 G37 G39 R40 R41 Y42 H55 R57 W84 F85 N87 R88 Q89 H99 L109 H122 R123 R126 H127 R132 V133 R134 G135 Q136 H137 T138 K139 T140 T141 R143 R144 I25 K26 Y29 I34 K35 G36 G38 R39 R40 Y41 H54 R56 W83 F84 N86 R87 Q88 H98 L108 H121 R122 R125 H126 R131 V132 R133 G134 Q135 H136 T137 K138 T139 T140 R142 R143 P0CX55 25043550 SLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLANNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA 1vxw T 6.20 BS01 NUC g 1 P2 G3 V4 S5 R7 A11 I15 K38 S41 E44 M45 P46 P47 Q48 K56 H64 Y66 R68 K69 V73 G74 K75 K78 L79 G81 G82 A83 R86 G87 V88 R89 Y91 K92 H93 S97 G98 S99 R102 K119 R122 R123 E126 Q129 R130 D133 P1 G2 V3 S4 R6 A10 I14 K37 S40 E43 M44 P45 P46 Q47 K55 H63 Y65 R67 K68 V72 G73 K74 K77 L78 G80 G81 A82 R85 G86 V87 R88 Y90 K91 H92 S96 G97 S98 R101 K118 R121 R122 E125 Q128 R129 D132 P07280 25043550 PGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE 1vxw U 6.20 BS01 NUC g 1 R23 T25 E35 K53 G54 P55 V56 R57 L58 P59 T60 K61 V62 R68 K69 T70 P71 N72 G73 E74 G75 K77 T78 W79 R85 H87 R89 Y90 R9 T11 E21 K39 G40 P41 V42 R43 L44 P45 T46 K47 V48 R54 K55 T56 P57 N58 G59 E60 G61 K63 T64 W65 R71 H73 R75 Y76 P38701 25043550 QQQQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVASN 1vxw W 6.20 BS01 NUC g 1 T2 R3 S4 D9 N12 K19 R28 S31 K32 H56 R57 K71 S76 N80 V81 K88 T105 T106 S107 I110 R118 K119 H120 S122 G123 K124 Y130 T1 R2 S3 D8 N11 K18 R27 S30 K31 H55 R56 K70 S75 N79 V80 K87 T104 T105 S106 I109 R117 K118 H119 S121 G122 K123 Y129 P0C0W1 25043550 TRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY 1vxw X 6.20 BS01 NUC g 1 G2 K3 G4 K5 P6 R7 G8 L9 N10 S11 R13 K14 R19 R20 N22 R23 W24 A25 E26 Y29 K31 R32 T36 F38 S46 S47 H48 A49 K50 K62 Q63 N65 S66 A67 I68 R69 K70 R73 K78 N89 D90 G91 G106 F107 G108 R109 K110 G111 K112 A113 K114 G115 D116 G119 R121 K123 L133 W136 K139 G1 K2 G3 K4 P5 R6 G7 L8 N9 S10 R12 K13 R18 R19 N21 R22 W23 A24 E25 Y28 K30 R31 T35 F37 S45 S46 H47 A48 K49 K61 Q62 N64 S65 A66 I67 R68 K69 R72 K77 N88 D89 G90 G105 F106 G107 R108 K109 G110 K111 A112 K113 G114 D115 G118 R120 K122 L132 W135 K138 P0CX29 25043550 GKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS 1vxw Y 6.20 BS01 NUC g 1 T9 R10 K11 V12 R32 A33 N34 S36 K37 Y48 F58 G59 F60 R61 T62 Q63 F64 G65 Y89 R93 R105 R108 K109 Q110 K112 N113 K116 K117 F119 G120 T121 K123 R124 K127 K128 R131 R132 T8 R9 K10 V11 R31 A32 N33 S35 K36 Y47 F57 G58 F59 R60 T61 Q62 F63 G64 Y88 R92 R104 R107 K108 Q109 K111 N112 K115 K116 F118 G119 T120 K122 R123 K126 K127 R130 R131 P0CX31 25043550 SDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD 1vxw Z 6.20 BS01 NUC g 1 A36 A39 G73 S74 R77 R81 H95 S96 A1 A4 G38 S39 R42 R46 H60 S61 Q3E792 25043550 AQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRAT 1vxw a 6.20 BS01 NUC g 1 P2 K3 K4 R5 S7 N8 R10 N11 K12 K13 G14 R15 H17 K32 K34 K37 R38 K70 S76 I79 R85 V86 R87 S88 R89 R92 R95 A96 P97 P1 K2 K3 R4 S6 N7 R9 N10 K11 K12 G13 R14 H16 K31 K33 K36 R37 K69 S75 I78 R84 V85 R86 S87 R88 R91 R94 A95 P96 P39938 25043550 PKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPP 1vxw b 6.20 BS01 NUC g 1 R17 H19 K20 K22 Q26 P28 S30 Y31 F32 F47 H49 Q51 P66 T67 G68 G69 K70 R16 H18 K19 K21 Q25 P27 S29 Y30 F31 F46 H48 Q50 P65 T66 G67 G68 K69 P35997 25043550 VLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK 1vxw c 6.20 BS01 NUC g 1 R18 G20 S21 R22 G23 P47 R14 G16 S17 R18 G19 P43 Q3E7X9 25043550 TPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR 1vxw d 6.20 BS01 NUC g 1 V6 W7 F8 S9 H10 R12 Y14 G15 K16 G17 R19 C24 H27 T28 G29 L30 I31 R32 K33 Y34 R40 Q41 C42 K54 F55 R56 V3 W4 F5 S6 H7 R9 Y11 G12 K13 G14 R16 C21 H24 T25 G26 L27 I28 R29 K30 Y31 R37 Q38 C39 K51 F52 R53 P41057 25043550 ENVWFSHPRRYGKGSRQCRVCSSHTGLIRKYGLNICRQCFREKANDIGFNKFR 1vxw e 6.20 BS01 NUC g 1 A2 R10 K13 V14 Q17 T18 V21 K23 T24 E25 K26 K28 P30 K31 G32 R33 A34 R37 L39 V45 N46 M56 N57 P60 A1 R9 K12 V13 Q16 T17 V20 K22 T23 E24 K25 K27 P29 K30 G31 R32 A33 R36 L38 V44 N45 M55 N56 P59 P0CX33 25043550 AKVHGSLARAGKVKSQTPKVEKTEKPKKPKGRAYKRLLYTRRFVNVTLVNGKRRMNPGPS 1vxw f 6.20 BS01 NUC g 1 I91 H93 K94 H95 Y105 R118 F131 A133 N134 H135 R138 Y140 G142 H145 S146 K149 I10 H12 K13 H14 Y24 R37 F50 A52 N53 H54 R57 Y59 G61 H64 S65 K68 P05759 25043550 KKVYTTPKKIKHKHKKVKLAVLSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA 1vxz A 6.30 BS01 NUC g 1 N28 H32 R101 P104 T108 N109 T112 E135 Y138 N27 H31 R100 P103 T107 N108 T111 E134 Y137 P32905 25043550 SLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDP 1vxz B 6.30 BS01 NUC g 1 P23 F24 V65 V114 K116 W117 Q118 L120 R136 F138 Q146 N148 Q149 V150 K151 H153 Y155 Q157 S158 S159 R162 R165 K166 K202 I204 F205 K216 P4 F5 V46 V95 K97 W98 Q99 L101 R117 F119 Q127 N129 Q130 V131 K132 H134 Y136 Q138 S139 S140 R143 R146 K147 K183 I185 F186 K197 P33442 25043550 VVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHG 1vxz C 6.30 BS01 NUC g 1 V86 Q87 K88 Q89 T90 R91 A92 G93 R95 K116 K157 T159 K161 C162 G163 S164 V165 R168 I170 V179 A180 S181 Y197 T198 Q199 N201 G202 K203 T204 R205 T206 E208 N209 F224 V53 Q54 K55 Q56 T57 R58 A59 G60 R62 K83 K124 T126 K128 C129 G130 S131 V132 R135 I137 V146 A147 S148 Y164 T165 Q166 N168 G169 K170 T171 R172 T173 E175 N176 F191 P25443 25043550 GWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLLPGLQDEVMNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIPIRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPAVKKLLQLAGVEDVYTQSNGKTRTLENTLKAAFVAIGNTYGFLTPNLWAEQPLPVSPLDIYSDEASAQ 1vxz D 6.30 BS01 NUC g 1 L4 I5 S6 K7 K8 R9 R143 A144 R146 A147 K151 L157 I158 H159 S160 G161 Q162 H174 Q179 V181 L182 G183 K185 P203 D204 L2 I3 S4 K5 K6 R7 R141 A142 R144 A145 K149 L155 I156 H157 S158 G159 Q160 H172 Q177 V179 L180 G181 K183 P201 D202 P05750 25043550 ALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPILAPSVKDY 1vxz E 6.30 BS01 NUC g 1 A2 R3 G4 P5 K6 K7 H8 K10 L12 A13 H16 L19 D21 K22 C26 Y27 P29 R30 A33 G34 P35 H36 K37 L38 N57 R59 K62 A63 M66 Y82 K106 R108 L131 G132 K133 K134 V140 G144 R145 T146 R148 K155 R187 N188 H197 R200 H201 D202 F205 R255 A1 R2 G3 P4 K5 K6 H7 K9 L11 A12 H15 L18 D20 K21 C25 Y26 P28 R29 A32 G33 P34 H35 K36 L37 N56 R58 K61 A62 M65 Y81 K105 R107 L130 G131 K132 K133 V139 G143 R144 T145 R147 K154 R186 N187 H196 R199 H200 D201 F204 R254 P0CX35 25043550 ARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL 1vxz F 6.30 BS01 NUC g 1 H72 A74 A78 N79 K80 R81 K84 N95 L97 M98 N100 G101 R102 N103 N104 G105 K106 K107 L108 K109 G153 R166 N169 R180 F184 R185 N186 I187 T189 I190 H53 A55 A59 N60 K61 R62 K65 N76 L78 M79 N81 G82 R83 N84 N85 G86 K87 K88 L89 K90 G134 R147 N150 R161 F165 R166 N167 I168 T170 I171 P26783 25043550 FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIFVAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLDIINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVNQAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR 1vxz F 6.30 BS02 NUC j 1 R148 G153 A154 A155 R157 E216 R129 G134 A135 A136 R138 E197 P26783 25043550 FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIFVAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLDIINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDVSPLRRVNQAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR 1vxz G 6.30 BS01 NUC g 1 N4 Q13 T15 S53 N56 D57 Q59 G60 K64 Q65 G66 V67 L76 R85 R87 R88 D89 G90 E91 R92 K93 R94 V108 K131 R132 L133 G134 K136 R137 N139 K143 R154 R159 R160 K164 K167 Y169 K171 P173 K174 I175 Q176 R177 V179 Q182 R183 L184 Q185 R186 K187 R188 Q190 R191 A192 K194 N197 A198 R202 N4 Q13 T15 S53 N56 D57 Q59 G60 K64 Q65 G66 V67 L76 R85 R87 R88 D89 G90 E91 R92 K93 R94 V108 K131 R132 L133 G134 K136 R137 N139 K143 R154 R159 R160 K164 K167 Y169 K171 P173 K174 I175 Q176 R177 V179 Q182 R183 L184 Q185 R186 K187 R188 Q190 R191 A192 K194 N197 A198 R202 P0CX37 25043550 MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEI 1vxz H 6.30 BS01 NUC g 1 P65 R96 R97 I98 L99 P100 K101 R104 T105 S106 R107 Q108 V109 Q110 K111 R114 S115 R116 T117 L118 T119 K148 L176 T177 K179 P62 R93 R94 I95 L96 P97 K98 R101 T102 S103 R104 Q105 V106 Q107 K108 R111 S112 R113 T114 L115 T116 K145 L173 T174 K176 P26786 25043550 PQAKILSQAPTELELQVAQAFVELENSSPELKAELRPLQFKSIREIDVAGGKKALAIFVPVPSLAGFHKVQTKLTRELEKKFQDRHVIFLAERRILPKPSRTSRQVQKRPRSRTLTAVHDKILEDLVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPS 1vxz I 6.30 BS01 NUC g 1 G2 I3 R5 R8 H9 K10 R11 A13 F21 R22 K23 K24 R25 K26 F27 L29 R31 Q32 P33 R42 I43 R47 T48 R49 G50 K54 Y55 R56 L58 N64 A68 G71 I72 S73 K75 S86 T97 K98 A99 K137 N138 A139 R141 S170 S171 P173 G174 Q175 S176 R178 D180 G181 G1 I2 R4 R7 H8 K9 R10 A12 F20 R21 K22 K23 R24 K25 F26 L28 R30 Q31 P32 R41 I42 R46 T47 R48 G49 K53 Y54 R55 L57 N63 A67 G70 I71 S72 K74 S85 T96 K97 A98 K125 N126 A127 R129 S158 S159 P161 G162 Q163 S164 R166 D168 G169 P0CX39 25043550 GISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK 1vxz J 6.30 BS01 NUC g 1 P2 R3 P5 R6 T7 Y8 S9 K10 T11 Y12 T14 P15 K16 R17 P18 Y19 S21 K37 N38 K39 K40 R44 S50 R53 R54 F71 E72 A75 R79 R82 K120 S121 H123 H124 R126 V127 T130 Q131 R132 H133 I140 N142 I143 P144 S145 F146 R149 P163 R168 P169 G170 R171 V172 A173 R175 N176 P1 R2 P4 R5 T6 Y7 S8 K9 T10 Y11 T13 P14 K15 R16 P17 Y18 S20 K36 N37 K38 K39 R43 S49 R52 R53 F70 E71 A74 R78 R81 K119 S120 H122 H123 R125 V126 T129 Q130 R131 H132 I139 N141 I142 P143 S144 F145 R148 P162 R167 P168 G169 R170 V171 A172 R174 N175 O13516 25043550 PRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGE 1vxz K 6.30 BS01 NUC g 1 M1 L2 M3 K5 R8 F27 N28 L40 K44 S48 S51 F59 Y64 M1 L2 M3 K5 R8 F27 N28 L40 K44 S48 S51 F59 Y64 Q08745 25043550 MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERN 1vxz L 6.30 BS01 NUC g 1 A12 P17 H18 I19 F20 W34 K36 N37 A38 G39 L40 K43 E50 L63 S65 I66 R67 K69 S77 K79 M80 H81 T83 V85 R88 Y90 H92 Y93 P95 K96 Y97 Y100 K102 R103 H104 K105 N106 Q127 R129 P130 I131 S132 K133 T134 R136 F137 K151 A11 P16 H17 I18 F19 W33 K35 N36 A37 G38 L39 K42 E49 L62 S64 I65 R66 K68 S76 K78 M79 H80 T82 V84 R87 Y89 H91 Y92 P94 K95 Y96 Y99 K101 R102 H103 K104 N105 Q126 R128 P129 I130 S131 K132 T133 R135 F136 K150 P0CX47 25043550 STELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF 1vxz M 6.30 BS01 NUC g 1 R43 G44 L45 R46 E47 T67 K114 V116 G117 A118 S119 R24 G25 L26 R27 E28 T48 K95 V97 G98 A99 S100 P48589 25043550 AEVTIEDALKVVLRTALVHDGLARGLRESTKALTRGEALLVVLVSSVTEANIIKLVEGLANDPENKVPLIKVADAKQLGEWAGLGKIDREGNARKVVGASVVVVKNWGAETDELSMIMEHFSQQ 1vxz N 6.30 BS01 NUC g 1 G2 R3 M4 H5 S6 G8 K9 G10 I11 S12 S13 S14 A15 I16 P17 R20 P47 S48 G51 T61 R64 K70 I71 M72 R73 K76 E86 D87 Y90 L91 K94 S97 H101 R104 N105 D108 K109 D110 K112 F113 R114 I116 R121 R124 L125 R127 Y128 Y129 G1 R2 M3 H4 S5 G7 K8 G9 I10 S11 S12 S13 A14 I15 P16 R19 P46 S47 G50 T60 R63 K69 I70 M71 R72 K75 E85 D86 Y89 L90 K93 S96 H100 R103 N104 D107 K108 D109 K111 F112 R113 I115 R120 R123 L124 R126 Y127 Y128 P05756 25043550 GRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN 1vxz O 6.30 BS01 NUC g 1 R18 Y20 N24 D25 F27 H29 G35 K36 E37 T38 R41 T43 G45 M46 K49 A50 D51 R52 E54 R90 P120 V121 P122 S123 D124 S125 T126 R127 K128 K129 G130 G131 R132 R133 R135 R136 R8 Y10 N14 D15 F17 H19 G25 K26 E27 T28 R31 T33 G35 M36 K39 A40 D41 R42 E44 R80 P110 V111 P112 S113 D114 S115 T116 R117 K118 K119 G120 G121 R122 R123 R125 R126 P06367 25043550 SQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL 1vxz P 6.30 BS01 NUC g 1 R18 P38 A39 R40 R43 R47 A54 G55 K59 R77 T78 H79 R81 N82 Y97 N98 G99 K100 F102 Y115 G117 S120 I121 T122 Y123 T124 V126 H128 R11 P31 A32 R33 R36 R40 A47 G48 K52 R70 T71 H72 R74 N75 Y90 N91 G92 K93 F95 Y108 G110 S113 I114 T115 Y116 T117 V119 H121 Q01855 25043550 KKRVFKTHSYRGVDLEKLLEMSTEDFVKLAPARVRRRFARGMTSKPAGFMKKLRAAKLAAPENEKPAPVRTHMRNMIIVPEMIGSVVGIYNGKAFNQVEIRPEMLGHYLGEFSITYTPVRHGRA 1vxz Q 6.30 BS01 NUC g 1 Q8 F10 K12 K14 S15 T17 V19 H21 L28 K30 N32 G33 P41 R68 G71 G72 G73 H74 V75 S76 Q77 I118 S121 R122 R123 P124 E125 P126 K127 K128 F129 G130 G131 K132 G133 A134 R135 S136 R137 F138 Q139 K140 S141 Y142 R143 Q6 F8 K10 K12 S13 T15 V17 H19 L26 K28 N30 G31 P39 R66 G69 G70 G71 H72 V73 S74 Q75 I116 S119 R120 R121 P122 E123 P124 K125 K126 F127 G128 G129 K130 G131 A132 R133 S134 R135 F136 Q137 K138 S139 Y140 R141 P0CX51 25043550 AVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR 1vxz R 6.30 BS01 NUC g 1 G2 R3 V4 R5 K7 T8 K10 F28 K32 S43 K44 R45 L46 N48 K49 G52 R67 S125 G1 R2 V3 R4 K6 T7 K9 F27 K31 S42 K43 R44 L45 N47 K48 G51 R66 S119 P02407 25043550 GRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSA 1vxz T 6.30 BS01 NUC g 1 P2 G3 R7 A11 Q12 I15 Y33 K38 T39 S41 N43 E44 M45 P47 Q48 S60 R63 H64 Y66 M67 R68 K69 G72 V73 G74 K75 K78 L79 Y80 G82 S85 R86 G87 V88 R89 P90 Y91 H93 S97 G98 S99 R102 K119 G120 R122 R123 Q129 R130 D133 P1 G2 R6 A10 Q11 I14 Y32 K37 T38 S40 N42 E43 M44 P46 Q47 S59 R62 H63 Y65 M66 R67 K68 G71 V72 G73 K74 K77 L78 Y79 G81 S84 R85 G86 V87 R88 P89 Y90 H92 S96 G97 S98 R101 K118 G119 R121 R122 Q128 R129 D132 P07280 25043550 PGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE 1vxz U 6.30 BS01 NUC g 1 R23 E35 K53 G54 V56 R57 L58 P59 T60 S66 T67 R68 K69 T70 N72 G73 E74 G75 K77 T78 W79 R85 R89 Y90 R9 E21 K39 G40 V42 R43 L44 P45 T46 S52 T53 R54 K55 T56 N58 G59 E60 G61 K63 T64 W65 R71 R75 Y76 P38701 25043550 QQQQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVASN 1vxz W 6.30 BS01 NUC g 1 T2 R3 S4 V6 N12 N16 K19 R28 S30 S31 K32 H56 R57 S58 K71 S76 R78 N80 V81 K82 I83 W89 T105 T106 S107 R118 K119 H120 S122 K124 F128 Y130 T1 R2 S3 V5 N11 N15 K18 R27 S29 S30 K31 H55 R56 S57 K70 S75 R77 N79 V80 K81 I82 W88 T104 T105 S106 R117 K118 H119 S121 K123 F127 Y129 P0C0W1 25043550 TRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY 1vxz X 6.30 BS01 NUC g 1 G2 K3 G4 K5 P6 R7 G8 L9 N10 S11 R13 K14 R19 R20 N22 R23 W24 A25 E26 N27 R32 F38 S46 S47 H48 K50 K62 N65 S66 A67 I68 R69 K70 I77 K78 N89 D90 G106 F107 G108 R109 K110 G111 K114 D116 R121 K123 K139 G1 K2 G3 K4 P5 R6 G7 L8 N9 S10 R12 K13 R18 R19 N21 R22 W23 A24 E25 N26 R31 F37 S45 S46 H47 K49 K61 N64 S65 A66 I67 R68 K69 I76 K77 N88 D89 G105 F106 G107 R108 K109 G110 K113 D115 R120 K122 K138 P0CX29 25043550 GKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS 1vxz Y 6.30 BS01 NUC g 1 R8 T9 R10 K11 V12 K21 A33 N34 V35 S36 K37 V47 Y48 G59 F60 R61 T62 Q63 F64 G65 G66 Y89 R105 Q106 R108 K109 Q110 K112 N113 K116 K117 F119 G120 T121 K123 R124 K127 R132 R7 T8 R9 K10 V11 K20 A32 N33 V34 S35 K36 V46 Y47 G58 F59 R60 T61 Q62 F63 G64 G65 Y88 R104 Q105 R107 K108 Q109 K111 N112 K115 K116 F118 G119 T120 K122 R123 K126 R131 P0CX31 25043550 SDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD 1vxz Z 6.30 BS01 NUC g 1 A36 G73 S74 R77 R81 K94 H95 A1 G38 S39 R42 R46 K59 H60 Q3E792 25043550 AQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRAT 1vxz a 6.30 BS01 NUC g 1 P2 K3 K4 R5 A6 S7 N8 G9 R10 N11 K12 K13 G14 R15 H17 K28 K32 K34 K37 R38 K70 V75 S76 I79 V84 R85 V86 R87 S88 R89 R92 N94 R95 A96 P97 P1 K2 K3 R4 A5 S6 N7 G8 R9 N10 K11 K12 G13 R14 H16 K27 K31 K33 K36 R37 K69 V74 S75 I78 V83 R84 V85 R86 S87 R88 R91 N93 R94 A95 P96 P39938 25043550 PKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPP 1vxz b 6.30 BS01 NUC g 1 R17 H19 K20 L21 K22 P28 S30 F32 F47 H49 Q51 P66 T67 G68 G69 K70 R16 H18 K19 L20 K21 P27 S29 F31 F46 H48 Q50 P65 T66 G67 G68 K69 P35997 25043550 VLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK 1vxz d 6.30 BS01 NUC g 1 W7 F8 S9 H10 R12 R13 Y14 G15 K16 G17 R19 C24 T28 G29 I31 R32 K33 Y34 R40 Q41 R44 K54 F55 R56 W4 F5 S6 H7 R9 R10 Y11 G12 K13 G14 R16 C21 T25 G26 I28 R29 K30 Y31 R37 Q38 R41 K51 F52 R53 P41057 25043550 ENVWFSHPRRYGKGSRQCRVCSSHTGLIRKYGLNICRQCFREKANDIGFNKFR 1vxz e 6.30 BS01 NUC g 1 R10 V14 V21 E22 K23 E25 K26 K28 P30 K31 R33 A34 K36 L38 L39 R42 V45 M56 N57 P58 P60 R9 V13 V20 E21 K22 E24 K25 K27 P29 K30 R32 A33 K35 L37 L38 R41 V44 M55 N56 P57 P59 P0CX33 25043550 AKVHGSLARAGKVKSQTPKVEKTEKPKKPKGRAYKRLLYTRRFVNVTLVNGKRRMNPGPS 1vxz f 6.30 BS01 NUC g 1 T87 P88 K89 K92 H93 K94 H95 V98 K99 L100 A101 Y105 R118 V130 F131 A133 N134 H135 R138 Y140 G142 K143 H145 S146 K149 T6 P7 K8 K11 H12 K13 H14 V17 K18 L19 A20 Y24 R37 V49 F50 A52 N53 H54 R57 Y59 G61 K62 H64 S65 K68 P05759 25043550 KKVYTTPKKIKHKHKKVKLAVLSYYKVDAEGKVTKLRRECSNPTCGAGVFLANHKDRLYCGKCHSVYKVNA 2mny A BS01 ZN A 1 C312 C315 H335 C338 C7 C10 H30 C33 1.14.11.- Q9UGL1 24952722 AVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 2mny A BS02 ZN A 2 C327 C330 C353 C356 C22 C25 C48 C51 1.14.11.- Q9UGL1 24952722 AVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 2mnz A BS01 III B 1 V307 D308 Y310 V311 G316 S317 G318 N319 E321 L324 L325 L326 D328 V346 P347 K348 G349 D350 W351 V2 D3 Y5 V6 G11 S12 G13 N14 E16 L19 L20 L21 D23 V41 P42 K43 G44 D45 W46 1.14.11.- Q9UGL1 24952722 AVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 2mnz A BS03 ZN A 2 C327 C330 D331 C353 C356 C22 C25 D26 C48 C51 1.14.11.- Q9UGL1 24952722 AVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQE 2mq1 A BS03 ZN A 3 C61 C67 H80 H85 C61 C67 H80 H85 6.3.2.- Q9JIY2 VHFCDKCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAG 3we4 A 2.00 BS02 5FI A 1 G98 K99 G100 Y102 G103 V105 A121 K123 L125 L172 E173 Y174 L175 M225 K241 G14 K15 G16 Y18 G19 V21 A37 K39 L41 L88 E89 Y90 L91 M141 K157 2.7.11.1 P23443 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 3wf5 A 2.10 BS02 FZ8 A 1 L97 G98 K99 G100 G103 V105 A121 V156 L172 E173 L175 M225 K241 L13 G14 K15 G16 G19 V21 A37 V60 L76 E77 L79 M129 K145 2.7.11.1 P23443 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 3wf6 A 2.03 BS02 FZ9 A 1 L97 G98 K99 G100 V105 A121 K123 V156 L172 E173 L175 M225 K241 L13 G14 K15 G16 V21 A37 K39 V60 L76 E77 L79 M129 K145 2.7.11.1 P23443 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 3wf7 A 1.85 BS02 FS9 A 1 L97 K99 G100 Y102 G103 K104 V105 A121 K123 L125 V156 E173 Y174 L175 M225 K241 L15 K17 G18 Y20 G21 K22 V23 A39 K41 L43 V74 E91 Y92 L93 M143 K159 2.7.11.1 P23443 PEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQ 3wf8 A 1.98 BS02 F76 A 1 L97 K99 G100 G101 Y102 G103 V105 A121 L125 V156 E173 Y174 L175 M225 C240 K241 L13 K15 G16 G17 Y18 G19 V21 A37 L41 V72 E89 Y90 L91 M141 C156 K157 2.7.11.1 P23443 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPL 3wf9 A 2.04 BS02 FS7 A 1 L97 K99 G100 G101 Y102 G103 V105 A121 L125 E173 Y174 L175 L239 C240 K241 L13 K15 G16 G17 Y18 G19 V21 A37 L41 E89 Y90 L91 L155 C156 K157 2.7.11.1 P23443 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPL 3wfw A 1.65 BS01 HEM A 1 L77 R80 H81 Y84 V86 H90 Y91 V94 Y122 L125 M129 L77 R80 H81 Y84 V86 H90 Y91 V94 Y122 L125 M129 B3DUZ1 MTREEIKMIQKSWLRVIDKMDEAGLLFYRRLFDVEPKVRPLFKIDIEKQGRKLMDVLNWIVLNLQDIDAALDAARELARRHVKYGVKAEHYPVVGHTLIWTLRKMIGSEWTKQLEQLWTQAYEALAQVMIEEHHHHHH 3wfx A 1.94 BS02 IMD A 1 F27 F42 V56 F27 F42 V56 B3DUZ1 MTREEIKMIQKSWLRVIDKMDEAGLLFYRRLFDVEPKVRPLFKIDIEKQGRKLMDVLNWIVLNLQDIDAALDAARELARRHVKYGVKAEHYPVVGHTLIWTLRKMIGSEWTKQLEQLWTQAYEALAQVMIEEHHHH 3wfx A 1.94 BS03 HEM B 1 L41 F42 K43 I44 V56 W59 I60 L41 F42 K43 I44 V56 W59 I60 B3DUZ1 MTREEIKMIQKSWLRVIDKMDEAGLLFYRRLFDVEPKVRPLFKIDIEKQGRKLMDVLNWIVLNLQDIDAALDAARELARRHVKYGVKAEHYPVVGHTLIWTLRKMIGSEWTKQLEQLWTQAYEALAQVMIEEHHHH 3wfx B 1.94 BS01 HEM A 1 L41 F42 K43 D55 V56 I60 L41 F42 K43 D55 V56 I60 B3DUZ1 MTREEIKMIQKSWLRVIDKMDEAGLLFYRRLFDVEPKVRPLFKIDIEKQGRKLMDVLNWIVLNLQDIDAALDAARELARRHVKYGVKAEHYPVVGHTLIWTLRKMIGSEWTKQLEQLWTQAYEALAQVMIEEHHH 3wfx B 1.94 BS02 IMD B 1 F27 Y28 F42 V56 F27 Y28 F42 V56 B3DUZ1 MTREEIKMIQKSWLRVIDKMDEAGLLFYRRLFDVEPKVRPLFKIDIEKQGRKLMDVLNWIVLNLQDIDAALDAARELARRHVKYGVKAEHYPVVGHTLIWTLRKMIGSEWTKQLEQLWTQAYEALAQVMIEEHHH 3wmt A 1.50 BS01 CA A 1 D272 D275 A277 D279 I281 D235 D238 A240 D242 I244 3.1.1.73 Q2UP89 SFQAECESFKAKINVTNANVHSVTYVPAGVNISMADNPSICGGDPITSTFAFCRIALNVTTSSKSQIFMEAWLPSNYSGRFLSTGNGGLGGCVKYDDMAYAAGYGFATVGTNNGHFGNNGVSFYQNTEVVEDFAYRALHTGVVVGKELTKNFYPQGYNKSYYLGCSTGGRQGWKSVQTFPDDFDGVVAGAPAFNFINLTSWGARFLTLTGDSSAETFVTETQWTAVHNEIIRQCDSLDGAKDGIIEDPDLCQPIIEALLCNATQSSTSGTCLTGAQVKTVNGVFSATYGLNGSFLYPRMQPGSELAAYSSYYSGTPFAYAEDWYRYVVFNNTNWDVATWTVQDAAIANAQDPYQISTWNGDLSPFQKKGGKVLHYHGMEDAIISSESSKVYYKHVADTMNLSPSELDSFYRFFPISGMAHCANADGPSAIGQGTGTFAGNNPQDNVLLAMVQWVEEGVAPDFVRGAKLNGSTVEYRRKHCKYPKRNRYVGPGSYTDENAWECV 3wx1 A 1.93 BS01 ZN A 1 C326 C329 C394 C397 C7 C10 C75 C78 Q8C7D2 GPTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP 4byg A 2.85 BS01 ALF A 1 D426 K427 T428 T577 G578 N627 D353 K354 T355 T504 G505 N554 3.6.3.- Q5ZWR1 VSPEYLDMRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLLLATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAWIYSMVAVLWPGVFPHAFRSQEGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVSLDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTGSFVMKALHVGSDTMLARIVQMVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWALLGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGKGAQSGVLIKNAEALERMEKVNTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLSLGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMAVDGKTVALLVVEDPIKSSTPETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEIMPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIAMGTGTDVAIESAGVTLLHGDLRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALSSVSVIINALRLKRVTL 4bzp A 1.47 BS01 ADP A 1 G453 S454 G455 K456 S457 S458 R559 P561 R597 S598 I599 Q602 G14 S15 G16 K17 S18 S19 R120 P122 R158 S159 I160 Q163 2.7.1.25 A5U1Y4 PPRGKTVWFTGLSGSGKSSVAMLVERKLLEKGISAYVLDGDNLRHGLNADLGFSMADRAENLRRLSHVATLLADCGHLVLVPAISPLAEHRALARKVHADAGIDFFEVFCDTPLQDCERRDPKGLYAKARAGEITHFTGIDSPYQRPKNPDLRLTPDRSIDEQAQEVIDLLES 4c4u B 2.58 BS01 FE2 B 1 H14 H40 H46 C110 I112 H113 H13 H39 H45 C109 I111 H112 1.15.1.2 O29903 ELFQTADWKKQKHVPVIEVLRAEGGVVEVKVSVGKEIPHPNTTEHHIAWIELVFQPEGSKFPYVVGRAEFAAHGASVDGPNTSGVYTDPVAVFAFKAEKSGKLTAFSYCNIHGLWMGEATLSL 4cpe A 1.06 BS01 LUV A 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 A86 S88 T90 W92 W108 L110 S112 L124 D128 N8 L10 S12 Y28 S30 V32 G33 N34 W64 A71 S73 T75 W77 W93 L95 S97 L109 D113 P22629 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4cpe B 1.06 BS01 LUV B 1 N23 L25 S27 Y43 S45 V47 G48 N49 W79 S88 T90 W92 W108 L110 S112 D128 N8 L10 S12 Y28 S30 V32 G33 N34 W64 S73 T75 W77 W93 L95 S97 D113 P22629 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKV 4cpf B 1.14 BS01 LH3 B 1 N23 L25 S27 Y43 E44 S45 W79 R84 N85 A86 T90 W92 W108 D128 N8 L10 S12 Y28 E29 S30 W64 R69 N70 A71 T75 W77 W93 D113 P22629 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4cph B 1.64 BS01 LH4 B 1 N23 L25 S27 Y43 S45 S52 Y54 W79 R84 N85 A86 T90 W92 W108 L110 D128 N8 L10 S12 Y28 S30 S37 Y39 W64 R69 N70 A71 T75 W77 W93 L95 D113 P22629 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4cph C 1.64 BS01 LH4 C 1 N23 L25 S27 Y43 S45 S52 Y54 W79 N85 A86 S88 T90 W92 W108 L110 D128 N8 L10 S12 Y28 S30 S37 Y39 W64 N70 A71 S73 T75 W77 W93 L95 D113 P22629 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4cpi A 1.54 BS01 LH4 A 1 N23 L25 S27 Y43 S45 A46 V47 Y54 W79 Y83 R84 N85 D86 T90 W92 W108 D128 N8 L10 S12 Y28 S30 A31 V32 Y39 W64 Y68 R69 N70 D71 T75 W77 W93 D113 P22629 GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNDHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVK 4cpi B 1.54 BS01 LH4 B 1 N23 L25 S27 Y43 W79 D86 T90 W92 W108 L110 D128 N9 L11 S13 Y29 W62 D69 T73 W75 W91 L93 D111 P22629 AGITGTWYNQLGSTFIVTAGADGALTGTYESNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNDHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKP 4cri A 2.35 BS01 III C 1 W1495 N1498 Y1500 Y1502 D1521 Y1523 L1547 S1548 E1549 E1551 Y1552 F1553 A1585 I1587 W11 N14 Y16 Y18 D37 Y39 L63 S64 E65 E67 Y68 F69 A101 I103 Q12888 25049398 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4cri A 2.35 BS02 III D 1 K1514 L1528 K30 L44 Q12888 25049398 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4cri B 2.35 BS01 III D 1 W1495 N1498 Y1500 Y1502 D1521 L1547 S1548 E1549 E1551 Y1552 F1553 W11 N14 Y16 Y18 D37 L63 S64 E65 E67 Y68 F69 Q12888 25049398 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG 4csh A 1.79 BS02 ZN A 1 C54 G116 C53 G115 Q6Y7T6 25064136 AKTQAEINKRLDAYAKGTVDSPYRVKKATSYDPSFGVMEAGAIDADGYYHAQCQDLITDYVLWLTDNKVRTWGNAKDQIKQSYGTGFKIHENKPSTVPKKGWIAVFTSGSYEQWGHIGIVYDGGNTSTFTILEQNWNGYANKKPTKRVDNYYGLTHFIEIPVKA 4ct3 A 1.69 BS01 CMH A 1 Q53 Q55 D56 L57 A76 W115 G116 H117 I118 Q135 Q52 Q53 D54 L55 A74 W113 G114 H115 I116 Q133 Q6Y7T6 25064136 AKTQAEINKRLDAYAKGTVDSPYRVKKATSYDPSFGVMEAGAIDADGYYHAQQDLITDYVLWLTDNKVRTWGNAKDQIKQSYGTGFKIHENKPSTVPKKGWIAVFTSGSYEQWGHIGIVYDGGNTSTFTILEQNWNGYANKKPTKRVDNYYGLTHFIEIPVKA 4ct3 A 1.69 BS03 MMC A 1 K3 W64 D67 N68 K2 W62 D65 N66 Q6Y7T6 25064136 AKTQAEINKRLDAYAKGTVDSPYRVKKATSYDPSFGVMEAGAIDADGYYHAQQDLITDYVLWLTDNKVRTWGNAKDQIKQSYGTGFKIHENKPSTVPKKGWIAVFTSGSYEQWGHIGIVYDGGNTSTFTILEQNWNGYANKKPTKRVDNYYGLTHFIEIPVKA 4ctn A 2.10 BS01 M8P A 1 E88 N133 G135 L136 L139 N282 D283 N284 R292 D339 H341 H377 T378 N484 Y573 E672 A673 S674 G675 E77 N122 G124 L125 L128 N262 D263 N264 R272 D310 H312 H348 T349 N455 Y544 E643 A644 S645 G646 2.4.1.1 P00489 25009003 QISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPNDGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWDKAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQENKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFVVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPA 4cwu E 3.80 BS01 III V 1 S24 G26 Q29 S20 G22 Q25 P04133 25071205 MMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPTFKPYSGTAYNALAPKGAPNPCEWDTHVFGQAPYSGINITKEGIQIGVEGQTPKYADKTFQPEPQIGESQWYETEINHAAGRVLKKTTPMKPCYGSYAKPTNENGGQGILVKQQNGKLESQVEMQFFSTTEATAGNGDNLTPKVVLYSEDVDIETPDTHISYMPTIKEGNSRELMGQQSMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGVINTETLTKVKPKTGQENGWEKDATEFSDKNEIRVGNNFAMEINLNANLWRNFLYSNIALYLPDKLKYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYINLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGILHQHNNSGFVGYLAPTMREGQAYPANFPYPLIGKTAVDSITQKKFLCDRTLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRVHRPHRGVIETVYLRTPFSA 4cwu Y 3.80 BS01 III V 1 E57 T64 E27 T34 P24936 25071205 INYMSAGPHMISRVNGIRAHRNRILLEQAAITTTPRNNLNPRSWPAALVYQESPAP 4d08 A 1.90 BS02 Q2T A 1 N704 T768 D808 L809 Q812 I826 F830 M847 M848 Q859 F862 N126 T190 D230 L231 Q234 I248 F252 M269 M270 Q281 F284 3.1.4.17 O00408 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD 4d08 B 1.90 BS02 Q2T B 1 N704 T768 L770 T805 D808 L809 Q812 I826 F830 M847 M848 Q859 F862 N125 T189 L191 T226 D229 L230 Q233 I247 F251 M268 M269 Q280 F283 3.1.4.17 O00408 DEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 4d08 C 1.90 BS02 Q2T C 1 H656 T768 L770 D808 L809 Q812 I826 F830 M845 M847 M848 Q859 F862 H67 T179 L181 D219 L220 Q223 I237 F241 M256 M258 M259 Q270 F273 3.1.4.17 O00408 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 4d08 D 1.90 BS02 Q2T D 1 H656 N704 T768 L770 D808 Q812 I826 F830 M845 M847 M848 Q859 F862 H70 N118 T182 L184 D222 Q226 I240 F244 M259 M261 M262 Q273 F276 3.1.4.17 O00408 KLLIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 4d09 A 2.50 BS01 788 A 1 L770 L774 D808 L809 Q812 I826 M847 Q859 F862 L192 L196 D230 L231 Q234 I248 M269 Q281 F284 3.1.4.17 O00408 DDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDE 4d09 B 2.50 BS01 788 B 1 L770 L809 Q812 F830 M847 Q859 F862 L191 L230 Q233 F251 M268 Q280 F283 3.1.4.17 O00408 DEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD 4d09 B 2.50 BS03 MG B 1 D697 T768 D118 T189 3.1.4.17 O00408 DEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLD 4d09 C 2.50 BS01 788 C 1 Y655 L770 L774 L809 Q812 M847 Q859 F862 I866 Y68 L183 L187 L222 Q225 M260 Q272 F275 I279 3.1.4.17 O00408 DGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 4d09 C 2.50 BS03 MG C 1 H656 D697 H700 H69 D110 H113 3.1.4.17 O00408 DGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFL 4d09 D 2.50 BS01 788 D 1 L770 L774 L809 Q812 I822 M847 Q859 F862 L181 L185 L220 Q223 I233 M258 Q270 F273 3.1.4.17 O00408 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDF 4d09 D 2.50 BS03 MG D 1 D697 H700 E727 H730 D108 H111 E138 H141 3.1.4.17 O00408 IQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDF 4d0y B 2.00 BS04 ZN B 4 E90 K95 Y116 E36 K41 Y62 3.4.17.13 Q04LP8 25060741 AEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFDVIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEIAESGLSLEEYYGFEGGDYVD 4d0y B 2.00 BS05 ZN B 5 E97 K100 E43 K46 3.4.17.13 Q04LP8 25060741 AEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFDVIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEIAESGLSLEEYYGFEGGDYVD 4j1v A 1.95 BS01 III E 1 P91 R92 Y93 E94 Y95 H96 W97 D99 Y114 R154 R157 R199 P51 R52 Y53 E54 Y55 H56 W57 D59 Y68 R108 R111 R153 Q9H8S9 LRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG 4j1v A 1.95 BS02 III G 1 Y163 H164 F167 E176 A177 H178 N180 T181 K184 L204 L207 K210 L211 Y117 H118 F121 E130 A131 H132 N134 T135 K138 L158 L161 K164 L165 Q9H8S9 LRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG 4j1v A 1.95 BS03 ZN A 1 C79 C84 H161 H166 C39 C44 H115 H120 Q9H8S9 LRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG 4kwz D 3.44 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 R25 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 Y54 A55 L58 R59 K61 Q62 R66 E72 R73 Q74 N77 K85 K86 S113 R115 Q116 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 K151 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 R24 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 Y53 A54 L57 R58 K60 Q61 R65 E71 R72 Q73 N76 K84 K85 S112 R114 Q115 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 K150 L154 E155 E204 S207 R208 P80373 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4kx0 H 3.44 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 F109 S110 K138 Q139 Q143 A146 R152 Y157 H158 K160 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 F108 S109 K137 Q138 Q142 A145 R151 Y156 H157 K159 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 4kx0 N 3.44 BS01 NUC A 1 K2 T3 W13 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 K65 K66 Q69 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 R97 E100 H101 A102 G105 M106 P108 G110 P111 L112 R114 K118 K121 P129 K2 T3 W13 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 K65 K66 Q69 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 R97 E100 H101 A102 G105 M106 P108 G110 P111 L112 R114 K118 K121 P129 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 4kx0 Z 3.44 BS01 NUC B 1 P15 R19 Y29 N30 N34 R72 Q73 E84 H85 P15 R19 Y29 N30 N34 R72 Q73 E84 H85 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIA 4kx0 0 3.44 BS01 NUC A 1 A2 H3 K4 T10 R11 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 G28 Q29 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 L62 F69 R74 L75 R77 A1 H2 K3 T9 R10 N11 R13 D14 S15 Q16 A17 K18 R19 V22 K23 R24 Y25 E26 G27 Q28 A32 G33 N34 I35 R38 R40 G41 T42 R43 G53 R54 D55 F56 T57 F59 L61 F68 R73 L74 R76 P60493 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 4kx0 1 3.44 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 R26 G28 V30 G31 K32 K33 T34 T35 I37 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 R61 A64 S65 H66 R76 K78 K88 E93 L94 K96 L97 L98 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 R25 G27 V29 G30 K31 K32 T33 T34 I36 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 R60 A63 S64 H65 R75 K77 K87 E92 L93 K95 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4kx0 7 3.44 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 M22 P25 R28 K29 K32 R33 R34 R35 Q36 K37 R39 W40 R41 R47 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 M22 P25 R28 K29 K32 R33 R34 R35 Q36 K37 R39 W40 R41 R47 K48 R49 P80340 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 4kx1 B 3.44 BS01 NUC A 1 W24 P26 R96 G99 G100 T103 N104 T107 R111 K133 R144 Y148 E176 K179 W21 P23 R93 G96 G97 T100 N101 T104 R108 K130 R141 Y145 E173 K176 P80371 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4kx1 C 3.44 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 K27 R127 S154 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 F186 R190 T192 Y193 G194 V195 L196 G197 K199 G1 N2 K3 I4 F9 K25 K26 R126 S153 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 F185 R189 T191 Y192 G193 V194 L195 G196 K198 P80372 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGE 4kx1 M 3.44 BS03 MG M 1 G100 Q101 R102 G99 Q100 R101 P80377 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 4kx1 Q 3.44 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 R25 Q26 P28 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 R63 P64 I65 S66 K67 R68 K69 R70 R72 K87 R91 R92 N94 Y95 S97 L98 K100 R101 P1 K2 S11 K13 M14 Q15 K16 T17 R24 Q25 P27 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 R62 P63 I64 S65 K66 R67 K68 R69 R71 K86 R90 R91 N93 Y94 S96 L97 K99 R100 Q5SHP7 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 4kx1 T 3.44 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 R22 R23 R25 N26 K27 A28 K29 S31 T35 K38 K39 R57 E60 D64 K65 K68 S70 K74 A78 R79 K81 S82 R83 M85 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 R15 R16 R18 N19 K20 A21 K22 S24 T28 K31 K32 R50 E53 D57 K58 K61 S63 K67 A71 R72 K74 S75 R76 M78 G94 G95 G96 L97 S98 P80380 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4kx2 G 3.44 BS01 NUC A 1 K36 N40 G42 G44 E45 K47 A73 K74 I77 N79 L82 I88 R91 R128 N132 G154 D156 K35 N39 G41 G43 E44 K46 A72 K73 I76 N78 L81 I87 R90 R127 N131 G153 D155 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4kx2 G 3.44 BS02 NUC B 1 P2 N27 V28 W29 E30 Q66 K67 P68 A69 V70 T71 R91 V92 T93 R95 R98 P1 N26 V27 W28 E29 Q65 K66 P67 A68 V69 T70 R90 V91 T92 R94 R97 Q5SHQ0 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4kx2 H 3.44 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 F109 S110 K138 Q139 Q143 A146 Y157 H158 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 F108 S109 K137 Q138 Q142 A145 Y156 H157 R169 Q5SHQ3 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 4kx2 N 3.44 BS01 NUC A 1 K2 T3 W13 L23 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 G64 K65 K66 Q69 Y72 R74 Y75 S76 Y78 G80 G81 K83 K89 R97 E100 H101 A102 K104 G105 M106 P108 G110 P111 L112 R114 K118 R119 K2 T3 W13 L23 G24 R25 T28 K29 T32 R35 K37 N45 F51 T63 G64 K65 K66 Q69 Y72 R74 Y75 S76 Y78 G80 G81 K83 K89 R97 E100 H101 A102 K104 G105 M106 P108 G110 P111 L112 R114 K118 R119 P60488 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 4kx2 S 3.44 BS02 NUC B 1 R15 R25 F29 R30 S31 L32 K33 Y36 Q38 I40 G45 V46 T47 S50 L54 A55 K57 N61 K62 T63 Y92 K93 H95 R97 R14 R24 F28 R29 S30 L31 K32 Y35 Q37 I39 G44 V45 T46 S49 L53 A54 K56 N60 K61 T62 Y91 K92 H94 R96 Q5SHQ4 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4kx2 Y 3.44 BS01 NUC A 1 R2 K4 H6 V7 K8 K9 G18 K19 K21 V30 P32 Y35 I44 K47 V49 V51 G59 F60 H68 S70 K71 R73 R84 V85 R1 K3 H5 V6 K7 K8 G17 K18 K20 V29 P31 Y34 I43 K46 V48 V50 G58 F59 H67 S69 K70 R72 R83 V84 Q5SHP9 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 4kx2 Z 3.44 BS01 NUC B 1 P15 R19 Y29 N30 R72 Q73 N75 E84 H85 D87 F89 P15 R19 Y29 N30 R72 Q73 N75 E84 H85 D87 F89 Q5SHZ1 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIA 4kx2 1 3.44 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 K25 R26 G28 G29 V30 G31 K32 K33 T34 T35 I37 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 R61 A64 S65 H66 K69 R76 K78 K88 E93 L94 L97 L98 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 K24 R25 G27 G28 V29 G30 K31 K32 T33 T34 I36 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 R60 A63 S64 H65 K68 R75 K77 K87 E92 L93 L96 L97 P60494 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4ky4 A 2.79 BS01 UMP A 1 C489 H490 Q509 R510 S511 D513 N521 H551 Y553 C368 H369 Q388 R389 S390 D392 N400 H430 Y432 1.5.1.3,2.1.1.45 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 A 2.79 BS02 04J A 1 V8 V9 A10 D31 F32 F35 S36 M87 F91 L94 R97 T172 V6 V7 A8 D29 F30 F33 S34 M53 F57 L60 R63 T119 1.5.1.3,2.1.1.45 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 A 2.79 BS03 NDP A 1 V9 A10 I17 G18 I19 N21 G22 L23 G80 R81 K82 T83 S86 V102 S103 S104 G153 A154 G155 Y157 V182 V7 A8 I15 G16 I17 N19 G20 L21 G46 R47 K48 T49 S52 V68 S69 S70 G100 A101 G102 Y104 V129 1.5.1.3,2.1.1.45 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 A 2.79 BS04 1UE A 1 E381 I402 W403 N406 D513 L516 G517 M608 A609 E260 I281 W282 N285 D392 L395 G396 M487 A488 1.5.1.3,2.1.1.45 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 B 2.79 BS03 04J B 1 V8 V9 D31 F32 F35 S36 F91 R97 V6 V7 D29 F30 F33 S34 F57 R63 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 B 2.79 BS04 NDP B 1 V9 A10 I17 G18 N21 G22 L23 W25 G80 R81 K82 T83 S86 V102 S103 S104 S105 A128 G153 A154 V182 V7 A8 I15 G16 N19 G20 L21 W23 G46 R47 K48 T49 S52 V68 S69 S70 S71 A76 G100 A101 V129 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 B 2.79 BS05 1UE B 1 W403 N406 D513 L516 G517 F520 M608 A609 W284 N287 D394 L397 G398 F401 M489 A490 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 C 2.79 BS01 UMP C 1 Y429 C489 H490 Q509 R510 S511 D513 N521 H551 Y553 Y308 C368 H369 Q388 R389 S390 D392 N400 H430 Y432 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 C 2.79 BS04 1UE C 1 I402 W403 N406 D513 L516 G517 M608 A609 I281 W282 N285 D392 L395 G396 M487 A488 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 D 2.79 BS03 04J D 1 V8 V9 D31 F32 F35 S36 F91 L94 R97 V6 V7 D29 F30 F33 S34 F57 L60 R63 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 D 2.79 BS05 1UE D 1 W403 N406 D513 L516 G517 F520 M608 W284 N287 D394 L397 G398 F401 M489 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 E 2.79 BS02 04J E 1 V8 V9 A10 D31 F32 F35 S36 F91 L94 R97 V151 T172 V6 V7 A8 D29 F30 F33 S34 F57 L60 R63 V99 T119 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 F 2.79 BS03 04J F 1 V8 V9 A10 D31 F32 F35 S36 F91 R97 V6 V7 A8 D29 F30 F33 S34 F57 R63 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 F 2.79 BS05 1UE F 1 E381 W403 N406 D513 L516 G517 F520 M608 E262 W284 N287 D394 L397 G398 F401 M489 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 H 2.79 BS04 NDP H 1 V9 A10 I17 I19 N21 G22 W25 G80 R81 K82 T83 S86 V102 S103 S104 G153 A154 V7 A8 I15 I17 N19 G20 W23 G46 R47 K48 T49 S52 V68 S69 S70 G100 A101 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4ky4 H 2.79 BS05 1UE H 1 I402 W403 D513 L516 G517 M608 A609 I283 W284 D394 L397 G398 M489 A490 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya A 3.26 BS02 1UG A 1 I402 N406 D513 L516 F520 Y553 M608 A609 I302 N306 D413 L416 F420 Y453 M508 A509 1.5.1.3,2.1.1.45 Q07422 24470841 PVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPASRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEEEYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKATYRPIFISKTFSDNGVPYDFVVLEKRRSSAAAIAPVLAWMDELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya A 3.26 BS03 NDP A 1 V9 A10 I17 G18 N21 G22 W25 G80 R81 K82 T83 V102 S103 S104 S105 A128 V151 G152 G153 A154 G155 L156 Y157 V182 V6 A7 I14 G15 N18 G19 W22 G50 R51 K52 T53 V72 S73 S74 S75 A98 V121 G122 G123 A124 G125 L126 Y127 V152 1.5.1.3,2.1.1.45 Q07422 24470841 PVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPASRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEEEYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKATYRPIFISKTFSDNGVPYDFVVLEKRRSSAAAIAPVLAWMDELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya B 3.26 BS03 1UG B 1 I402 N406 D513 L516 G517 F520 M608 A609 I283 N287 D394 L397 G398 F401 M489 A490 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya B 3.26 BS04 NDP B 1 A10 I17 G18 N21 G22 R81 K82 T83 S86 V102 S103 S104 G153 A154 Y157 A8 I15 G16 N19 G20 R47 K48 T49 S52 V68 S69 S70 G100 A101 Y104 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya C 3.26 BS02 1UG C 1 E381 I402 W403 N406 L486 L516 F520 M608 A609 E281 I302 W303 N306 L386 L416 F420 M508 A509 1.5.1.3,2.1.1.45 Q07422 24470841 PVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPASRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEEEYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKATYRPIFISKTFSDNGVPYDFVVLEKRRSSAAAIAPVLAWMDELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya D 3.26 BS02 UMP D 1 L486 C489 H490 Q509 R510 S511 D513 N521 H551 Y553 L367 C370 H371 Q390 R391 S392 D394 N402 H432 Y434 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya D 3.26 BS03 1UG D 1 I402 N406 D513 L516 G517 F520 Y553 M608 A609 I283 N287 D394 L397 G398 F401 Y434 M489 A490 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya D 3.26 BS04 NDP D 1 V9 A10 I17 G18 N21 G22 G80 R81 K82 T83 S86 S103 S104 G153 A154 G155 Y157 V7 A8 I15 G16 N19 G20 G46 R47 K48 T49 S52 S69 S70 G100 A101 G102 Y104 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya E 3.26 BS02 1UG E 1 I402 W403 N406 D513 L516 F520 Y553 M608 A609 I302 W303 N306 D413 L416 F420 Y453 M508 A509 1.5.1.3,2.1.1.45 Q07422 24470841 PVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPASRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEEEYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKATYRPIFISKTFSDNGVPYDFVVLEKRRSSAAAIAPVLAWMDELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya F 3.26 BS03 1UG F 1 I402 N406 L486 D513 L516 G517 F520 Y553 M608 A609 I283 N287 L367 D394 L397 G398 F401 Y434 M489 A490 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya F 3.26 BS04 NDP F 1 V9 A10 I17 G18 N21 G22 R81 K82 T83 S86 V102 S103 S104 G153 A154 G155 Y157 A159 V7 A8 I15 G16 N19 G20 R47 K48 T49 S52 V68 S69 S70 G100 A101 G102 Y104 A106 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya G 3.26 BS01 UMP G 1 R344 L486 C489 H490 Q509 R510 S511 C512 D513 N521 H551 Y553 R244 L386 C389 H390 Q409 R410 S411 C412 D413 N421 H451 Y453 1.5.1.3,2.1.1.45 Q07422 24470841 PVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTTPASRFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKEEDIAAEKPQAEGQQRVRVCASLPAALSLLEEEYKDSVDQIFVVGGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKATYRPIFISKTFSDNGVPYDFVVLEKRRSSAAAIAPVLAWMDELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya H 3.26 BS03 1UG H 1 I402 W403 N406 D513 L516 G517 F520 Y553 M608 A609 I283 W284 N287 D394 L397 G398 F401 Y434 M489 A490 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4kya H 3.26 BS04 NDP H 1 A10 I17 G18 N21 G22 G80 R81 K82 T83 S86 S103 S104 G153 A154 Y157 A8 I15 G16 N19 G20 G46 R47 K48 T49 S52 S69 S70 G100 A101 Y104 1.5.1.3,2.1.1.45 Q07422 24470841 KPVCLVVAMTPKRGIGINNGLPWPHLTTDFKHFSRVTKTFNAVVMGRKTWESMPRKFRPLVDRLNIVVSSSLKVCASLPAALSLLEEEYKDSVDQIFVVGAGLYEAALSLGVASHLYITRVAREFPCDVFFPAFPGDDILSNKEATYRPIFISKTFSDNGVPYDFVVLEKRSSAAAIAPVLAWMDEEDKELIRAVPHVHFRGHEEFQYLDLIADIINNGRTMDDRTGVGVISKFGCTMRYSLDQAFPLLTTKRVFWKGVLEELLWFIRGDTNANHLSEKGVKIWDKNVTREFLDSRNLPHREVGDIGPGYGFQWRHFGAAYKDMHTDYTGQGVDQLKNVIQMLRTNPTDRRMLMTAWNPAALDEMALPPCHLLCQFYVNDQKELSCIMYQRSCDVGLGVPFNIASYSLLTLMVAHVCNLKPKEFIHFMGNTHVYTNHVEALKEQLRREPRPFPIVNILNKERIKEIDDFTAEDFEVVGYVPHGRIQMEMAV 4lqf A 2.30 BS01 ZN A 1 H113 E129 H15 E31 Q71TT1 SCNGLYYQGSCYILHSDYQMFSDAAANCTAESSTLPNKSDVMITWLIDYVEDTWGSDGNPITSDVSQEVRKYFCVKTM 4lxo A 1.42 BS01 CA A 1 E1364 E1392 Q1412 E39 E67 Q87 P02751 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPPLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYACRARGDNPDCSKPISINYRT 4lxo B 1.42 BS01 CA B 1 E1364 E1392 E39 E67 P02751 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPPLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYACRARGDNPDCSKPISINYRT 4lzu A 2.40 BS01 ZN A 1 D53 E74 D51 E72 P02754 VTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI 4m1k A 2.95 BS01 GDP A 1 H20 I21 D22 A23 G24 K25 T26 T27 N137 K138 D140 K141 S262 A263 L264 H15 I16 D17 A18 G19 K20 T21 T22 N105 K106 D108 K109 S230 A231 L232 P13551 EYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRIAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRLTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLI 4m3a A 1.96 BS01 ANP A 1 I52 Q57 G58 V60 A73 K75 M128 E129 L130 M131 N134 S175 N176 V178 L188 I24 Q29 G30 V32 A45 K47 M100 E101 L102 M103 N106 S147 N148 V150 L160 2.7.11.24 P92208 QHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYSFDRLFPDGLFPNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAEPYDHSVDERHTVEQWKELIYEEVM 4mb2 A 2.19 BS01 ATP A 1 A36 R39 G40 L161 D163 D181 L182 N183 D198 N199 I200 A28 R31 G32 L153 D155 D173 L174 N175 D190 N191 I192 6.3.2.26 B6YXQ1 24021277 PRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLLHIRDRLTKLAEGGIWRKKQL 4mb2 A 2.19 BS02 ATP B 1 R17 Y45 R9 Y37 6.3.2.26 B6YXQ1 24021277 PRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLLHIRDRLTKLAEGGIWRKKQL 4mb2 B 2.19 BS01 ATP B 1 A36 R39 L161 E162 D163 G164 D181 L182 N183 R187 S188 D198 N199 I200 A35 R38 L160 E161 D162 G163 D180 L181 N182 R186 S187 D197 N198 I199 6.3.2.26 B6YXQ1 24021277 VKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLLHIRDRLTKLAEGGIWRKK 4mb2 D 2.19 BS01 ATP C 1 R10 R17 R4 R11 6.3.2.26 B6YXQ1 24021277 SHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHEGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLLHIRDRLTKLAEGGIWRKKQLD 4mb2 D 2.19 BS02 ATP D 1 A36 R39 L161 E162 D163 D181 L182 N183 S186 D198 N199 I200 A30 R33 L154 E155 D156 D174 L175 N176 S179 D191 N192 I193 6.3.2.26 B6YXQ1 24021277 SHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHEGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLLHIRDRLTKLAEGGIWRKKQLD 4mn7 B 2.00 BS01 SME B 1 W27 Y31 T48 G58 L59 C60 Y81 S84 E91 D107 D109 W27 Y31 T48 G58 L59 C60 Y81 S84 E91 D107 D109 Q9HJW5 25043974 MDLKEFARSQMQAACQYLKEKNPKYDWVGFYVLEHGKLKLEAFVGEKTDHVEINLGDGLCSLAVLKNDIVNEYDVKSNPKYLASFPSTQSEIVVPVRYQGEPIGEIDIDSDKKAAFSKEDEAMLSSIADLMAPLVHEFFVKL 4mvp A 1.80 BS01 HEM A 1 G104 L105 I107 R108 W111 V239 P241 F261 L274 I275 G278 H279 G282 K283 T284 H285 T323 S324 W330 L386 T388 F416 W420 G70 L71 I73 R74 W77 V205 P207 F227 L240 I241 G244 H245 G248 K249 T250 H251 T289 S290 W296 L352 T354 F382 W386 1.11.1.21 B7CLB5 24785434 NGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA 4nwc A 2.01 BS01 2QE A 1 E443 Y491 P518 L519 T520 R525 V687 G690 A691 T692 N722 E739 T742 Y765 E12 Y60 P87 L88 T89 R94 V136 G139 A140 T141 N171 E188 T191 Y214 P42264 25044437 TNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCP 4obw A 2.40 BS01 SAM A 1 Y78 K94 A119 G120 S122 D148 I149 N150 M153 N179 G180 S197 N202 F203 Y5 K21 A46 G47 S49 D75 I76 N77 M80 N106 G107 S124 N129 F130 2.1.1.201 P49017 VANRYDLMNDVMSLGIHRLWKDHFINKLDAGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSKIENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV 4obw D 2.40 BS01 SAM D 1 Y78 N82 K94 A119 G120 D124 D148 I149 N150 M153 N179 G180 S197 F198 N202 F203 Y6 N10 K22 A47 G48 D52 D76 I77 N78 M81 N107 G108 S125 F126 N130 F131 2.1.1.201 P49017 SVANRYDLMNDVMSLGIHRLWKDHFINKLDAGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSKIENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV 4obw C 2.40 BS01 SAM C 1 Y78 K94 A119 G120 D148 I149 N150 M153 N179 G180 S197 F198 R201 N202 F203 Y6 K22 A47 G48 D76 I77 N78 M81 N107 G108 S125 F126 R129 N130 F131 2.1.1.201 P49017 SVANRYDLMNDVMSLGIHRLWKDHFINKLDAGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSKIENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV 4ojk A 2.66 BS01 GDP A 1 D19 G21 V22 G23 K24 S25 N26 F36 N37 L38 E39 K41 N124 K125 D127 L128 S154 A155 L156 D14 G16 V17 G18 K19 S20 N21 F31 N32 L33 E34 K36 N119 K120 D122 L123 S149 A150 L151 3.6.5.2 Q15907 GSYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQK 4ojk B 2.66 BS01 GDP B 1 D19 G21 V22 G23 K24 S25 N26 F36 N37 L38 E39 N124 K125 D127 S154 A155 L156 D13 G15 V16 G17 K18 S19 N20 F30 N31 L32 E33 N106 K107 D109 S136 A137 L138 3.6.5.2 Q15907 SYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLEIGVEFATRSIQVDGKTIKAQIWDTITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQ 4p4m A 1.92 BS01 NUC D 1 H103 G104 G106 P107 R108 A109 R269 D271 H14 G15 G17 P18 R19 A20 R172 D174 Q9U6N3 24666693 KPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4m A 1.92 BS02 NUC E 1 A236 Q237 G238 P239 L240 K241 R273 K291 V295 R298 Q299 I302 L307 L308 N309 E310 Y311 N335 A336 E338 A147 Q148 G149 P150 L151 K152 R176 K194 V198 R201 Q202 I205 L210 L211 N212 E213 Y214 N229 A230 E232 Q9U6N3 24666693 KPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4m A 1.92 BS03 D3T A 1 G183 S184 R187 S192 G193 D194 D196 T286 F287 G289 K291 N294 G94 S95 R98 S103 G104 D105 D107 T189 F190 G192 K194 N197 Q9U6N3 24666693 KPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4m A 1.92 BS04 MG A 1 D194 D196 D105 D107 Q9U6N3 24666693 KPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4o A 2.30 BS01 NUC E 1 H103 G104 F105 G106 P107 R108 A109 K241 M243 R269 D271 H41 G42 F43 G44 P45 R46 A47 K179 M181 R199 D201 Q9U6N3 24666693 QEMADLNNALGEKYKVSSYHKLLKKATKPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4o A 2.30 BS02 NUC G 1 Y33 K34 S37 K68 Y14 K15 S18 K21 Q9U6N3 24666693 QEMADLNNALGEKYKVSSYHKLLKKATKPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4p A 2.30 BS01 NUC C 1 H103 G104 F105 G106 P107 R108 A109 D194 D196 M243 R269 D271 R273 T286 F287 T288 G289 K291 N294 H17 G18 F19 G20 P21 R22 A23 D108 D110 M157 R175 D177 R179 T192 F193 T194 G195 K197 N200 Q9U6N3 24666693 KYKVPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4p A 2.30 BS02 NUC D 1 Y33 K34 Y2 K3 Q9U6N3 24666693 KYKVPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4p4p A 2.30 BS03 NUC B 1 Y33 A236 Q237 G238 P239 L240 K241 V295 R298 Q299 I302 L307 L308 N309 E310 Y311 K334 N335 A336 E338 Y2 A150 Q151 G152 P153 L154 K155 V201 R204 Q205 I208 L213 L214 N215 E216 Y217 K240 N241 A242 E244 Q9U6N3 24666693 KYKVPKLKAIQELTQVHGFGPRAAAALFDREGIFTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSILICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGPLKYMGMGRLPPRINTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQAAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQDVFDVLGMPYAKPENRDP 4phr A 1.34 BS02 MN A 1 R116 H223 R121 H228 I1ZPA1 25023666 SEFELMKRLSEIKVLPILESLKYIKHNHASVVRFGDGEIDLMTGHSIPYQDYNEKLAKRLQQILQTKSDEKLLVCLPDVFSNMDRYNQNARHFWERHFLKYSEFYLNCCDAPFYGSTFISRPYIDLIDKSPSEAYFESLKELWRGKDLLIVEGATSRSGVGNDLFVAASSIKRLVCPSKNAFQYYDEILRLTEKNAKNRLILVMLGPTAKVLVADLTTKGYQAIDLGHIDSEYEWYEMGATYKVKLTNKHTAEFNYDEGIELEFSQEYQEQIVARIG 4phw A 2.50 BS02 2W1 A 1 Y514 H515 S667 V668 I682 Y683 F686 P702 M703 K708 E711 V712 G715 Q716 F719 Y61 H62 S214 V215 I229 Y230 F233 P249 M250 K255 E258 V259 G262 Q263 F266 3.1.4.17,3.1.4.35 Q9Y233 25062128 LPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRG 4phw B 2.50 BS02 2W1 B 1 S667 V668 I682 Y683 F686 P702 M703 E711 V712 G715 Q716 F719 S214 V215 I229 Y230 F233 P249 M250 E258 V259 G262 Q263 F266 3.1.4.17,3.1.4.35 Q9Y233 25062128 LPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRG 4pu3 A 3.39 BS01 NUC Q 1 R383 R384 Q387 R376 R377 Q380 Q8EIX3 25056321 TLEMHLGDLMIGELSFDATADTFAVHYTKDWQQSGFPLSPTIPLDGTGTSNQISMFLVNLLPENKGLDYLIESLGVSKGNTFALIRAIGLDTAGAIAFVPKGALLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYNGKEFAFAEGTLSSTHIVKFEKYHHLVINEFITMRLAKVLGMNVANVDIVHFGRYKALCVERFDRRNIPGEQRVLRRHIVDSCQALGFSVSKKYERNFGTGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFMDGLGLPRNLLISNLTRIARRIPQAIAEVILMLPPLDEDEASFVAHYKTQLLARCERYLGFVDEVRDVEV 4pu3 B 3.39 BS01 NUC P 1 R380 R384 R373 R377 Q8EIX3 25056321 TLEMHLGDLMIGELSFDATADTFAVHYTKDWQQSGFPLSPTIPLDGTGTSNQISMFLVNLLPENKGLDYLIESLGVSKGNTFALIRAIGLDTAGAIAFVPKGALLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYNGKEFAFAEGTLSSTHIVKFEKYHHLVINEFITMRLAKVLGMNVANVDIVHFGRYKALCVERFDRRNIPGEQRVLRRHIVDSCQALGFSVSKKYERNFGTGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFMDGLGLPRNLLISNLTRIARRIPQAIAEVILMLPPLDEDEASFVAHYKTQLLARCERYLGFVDEVRDVEV 4pu3 D 3.39 BS01 NUC Q 1 K34 R37 T43 Q44 K55 K56 I59 K63 Y68 K16 R19 T25 Q26 K37 K38 I41 K45 Y50 Q8EIX4 25056321 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIDIVSAGWY 4pu3 D 3.39 BS02 NUC P 1 V53 T54 K56 T57 R60 D66 V67 Y68 T71 V35 T36 K38 T39 R42 D48 V49 Y50 T53 Q8EIX4 25056321 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIDIVSAGWY 4pu3 C 3.39 BS01 NUC Q 1 G52 V53 T54 K56 T57 R60 D66 V67 Y68 T71 G34 V35 T36 K38 T39 R42 D48 V49 Y50 T53 Q8EIX4 25056321 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIDIVSAGWY 4pu3 C 3.39 BS02 NUC P 1 R37 T43 Q44 K55 K56 I59 K63 Y68 R19 T25 Q26 K37 K38 I41 K45 Y50 Q8EIX4 25056321 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIDIVSAGWY 4pu4 D 3.79 BS01 NUC Q 1 R38 T44 Q45 K57 I60 K64 Y69 R19 T25 Q26 K38 I41 K45 Y50 Q8EIX4 25056321 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIDIVSAQTSDTETNGW 4pu4 D 3.79 BS02 NUC P 1 G53 V54 T55 T58 R61 D67 V68 Y69 T72 G34 V35 T36 T39 R42 D48 V49 Y50 T53 Q8EIX4 25056321 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIDIVSAQTSDTETNGW 4pu5 A 1.83 BS01 MG A 1 N311 D328 N316 D333 Q8EIX3 25056321 PRGSHMSTAKTLTLEMHLGDLMIGELSFDATADTFAVHYTKDWQQSGFPLSPTIPLDGTGTSNQISMFLVNLLPENKGLDYLIESLGVSKGNTFALIRAIGLDTAGAIAFVPKGALLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYNGKEFAFAEGTLSSTHIVKFEKYHHLVINEFITMRLAKVLGMNVANVDIVHFGRYKALCVERFDRRNIPGEQRVLRRHIVDSCQALGFSVSKKYERNFGTGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFMDGLGLPRNLLISNLTRIARRIPQAIAEVILMLPPLDEDEASFVAHYKTQLLARCERYLGFVDEVRDVEV 4pu5 A 1.83 BS02 ANP A 1 A149 G150 V151 Q152 K154 I176 K178 A204 V219 E220 R221 F222 D223 H308 K310 N311 Y327 D328 A154 G155 V156 Q157 K159 I181 K183 A209 V224 E225 R226 F227 D228 H313 K315 N316 Y332 D333 Q8EIX3 25056321 PRGSHMSTAKTLTLEMHLGDLMIGELSFDATADTFAVHYTKDWQQSGFPLSPTIPLDGTGTSNQISMFLVNLLPENKGLDYLIESLGVSKGNTFALIRAIGLDTAGAIAFVPKGALLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYNGKEFAFAEGTLSSTHIVKFEKYHHLVINEFITMRLAKVLGMNVANVDIVHFGRYKALCVERFDRRNIPGEQRVLRRHIVDSCQALGFSVSKKYERNFGTGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFMDGLGLPRNLLISNLTRIARRIPQAIAEVILMLPPLDEDEASFVAHYKTQLLARCERYLGFVDEVRDVEV 4q1n A 2.09 BS01 2Y9 A 1 D32 G34 R74 Y75 S76 T77 P111 A115 F117 V120 I130 D215 G217 A218 I291 T295 D38 G40 R82 Y83 S84 T85 P118 A122 F124 V127 I137 D222 G224 A225 I301 T305 3.4.23.15 P00797 25050166 LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 4q1n B 2.09 BS01 2Y9 B 1 D32 G34 L73 R74 Y75 S76 T77 P111 A115 F117 V120 L213 D215 G217 A218 I291 T295 D38 G40 L81 R82 Y83 S84 T85 P118 A122 F124 V127 L220 D222 G224 A225 I301 T305 3.4.23.15 P00797 25050166 LTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 4q4c A 1.90 BS01 ADP A 1 R134 P149 V185 K187 H194 L211 E237 E238 F239 M240 D246 P265 D309 L311 C320 D321 R93 P108 V144 K146 H153 L170 E196 E197 F198 M199 D205 P224 D268 L270 C279 D280 2.7.4.21,2.7.4.24 O43314 25044992 RQIVVGICSMAKKSKSKPMKEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSIPLEAED 4q4c A 1.90 BS02 I8P A 1 K53 K54 H194 R213 K214 K248 R262 R273 R281 D309 D321 N323 S326 K329 K12 K13 H153 R172 K173 K207 R221 R232 R240 D268 D280 N282 S285 K288 2.7.4.21,2.7.4.24 O43314 25044992 RQIVVGICSMAKKSKSKPMKEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSIPLEAED 4q4d A 1.85 BS02 2YN A 1 K53 K54 S102 K103 K214 Y250 R262 R273 R281 S326 K329 K11 K12 S60 K61 K172 Y208 R220 R231 R239 S284 K287 2.7.4.21,2.7.4.24 O43314 25044992 QIVVGICSMAKKSKSKPMKEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPFVINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVFQKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWS 4q71 A 2.20 BS01 FAD A 1 D278 A279 A310 Q312 Y314 R339 V341 K342 G343 A344 Y345 W346 F364 T365 R366 K367 T370 A393 T394 H395 N396 Y441 S466 F467 D268 A269 A300 Q302 Y304 R329 V331 K332 G333 A334 Y335 W336 F354 T355 R356 K357 T360 A383 T384 H385 N386 Y431 S456 F457 1.5.99.8,1.2.1.88 Q89E26 25046425 MPNIPPPFTAPYAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRVPDARTADQFIEDKLGEGDFIHHETKSTAFLVNASAWARVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPGQKTRYSFDMLGEGARTAADARRYFDAYASAIETIGKAAGNHALPDRPGISVKLSALHPRFEAISRARVMVELVPQLLDLAQRAKAHDLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMVRLVKGAYWDTEIKRAQERGLDGYPVFTRKAMTDLNYVACASKLLALRPRIFPQFATHNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQAADYRVPVPALLQRPADAIVRPQAAAHPRIPLPCDLFAPERRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSRTPAGIRAAALEQAAHLLESRSAHFIALLQREGGKTLDDALSELREAADFCRYYAAQGRKLFGSETAMPGPTGESNALTMRGRGVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGIPKSALYLVTGDGRIGAALTAHPDIAGVVFTGSTEVARSINRALAAKDGPIVPLIAETGGINAMIADATALPEQVADWVVTSAFRSAGQRCSALRLLFVQEDVADRMIEMVAGAARELKIGDPSDVATHVGPVIDVEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVFGPILHVVRYRPENLERVLRAIERTGYGLTLGVHSRIDDSIEAIIDRVQVGNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA 4qa0 A 2.24 BS02 SHH A 1 Y100 H142 H143 G151 F152 D178 H180 F208 D267 G304 Y306 Y87 H129 H130 G138 F139 D165 H167 F195 D254 G291 Y293 3.5.1.98 Q9BY41 25075551 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFFYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVVIEGRGSH 4qa0 A 2.24 BS03 SHH B 1 P273 Y306 P260 Y293 3.5.1.98 Q9BY41 25075551 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFFYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVVIEGRGSH 4qa1 A 1.92 BS02 B3N A 1 Y100 D101 H142 H143 G151 F152 D178 H180 F208 D267 Y306 Y78 D79 H120 H121 G129 F130 D156 H158 F186 D245 Y284 3.5.1.98 Q9BY41 25075551 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHV 4qa5 A 1.76 BS01 III C 1 I94 D101 W141 E148 G151 F152 H180 G206 F208 P209 D267 M274 G304 F306 I81 D88 W128 E135 G138 F139 H167 G193 F195 P196 D254 M261 G291 F293 3.5.1.98 Q9BY41 25075551 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 4qa5 B 1.76 BS01 III D 1 I94 Y100 D101 W141 H143 E148 G151 F152 H180 F208 P209 G210 D267 G304 F306 I82 Y88 D89 W129 H131 E136 G139 F140 H168 F196 P197 G198 D255 G292 F294 3.5.1.98 Q9BY41 25075551 SLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVVIEGR 4qa6 B 2.05 BS01 III D 1 I94 Y100 D101 W141 E148 G151 F152 H180 F208 P209 D267 M274 G304 F306 I81 Y87 D88 W128 E135 G138 F139 H167 F195 P196 D254 M261 G291 F293 3.5.1.98 Q9BY41 25075551 LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQNCESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV 4qdj A 1.60 BS01 SAM A 1 V12 F16 Y28 H44 G70 C71 G72 S75 D91 I92 S93 M96 Q119 D120 L121 L134 D135 V136 H139 Y140 V11 F15 Y27 H43 G69 C70 G71 S74 D90 I91 S92 M95 Q118 D119 L120 L133 D134 V135 H138 Y139 2.1.1.11 Q55467 TNAALDDKTIVRDYFNSTGFDRWRRIYGDGQVNFVQKDIRVGHQQTVDSVVAWLVADGNLPGLLVCDAGCGVGSLSIPLAQAGALVYGSDISEKMVGEAQQKAQEVLAYGNQPTFMTQDLAQLGGKYDTVICLDVLIHYPTEEASAMISHLASLADRRLILSFAPKRAYQHKEADIRKILGDNGFSIARTGMTSTRFYYSRILEAVRS 4qfg A 3.46 BS01 STU A 1 L22 G23 V24 G25 V30 A43 I77 M93 E94 Y95 V96 G99 E100 E143 N144 L146 A156 D157 L14 G15 V16 G17 V22 A35 I69 M85 E86 Y87 V88 G91 E92 E135 N136 L138 A148 D149 2.7.11.1,2.7.11.27,2.7.11.31,2.7.11.26 P54645 GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDERPGSHTIEFFEMCANLIKILAQ 4qfg C 3.46 BS01 AMP C 1 H150 T199 I203 A204 V224 S225 A226 R298 I311 S313 S315 D316 H122 T171 I175 A176 V196 S197 A198 R263 I276 S278 S280 D281 P80385 SSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 4qfr A 3.34 BS02 32J A 1 V11 G19 K29 K31 I46 K51 D88 F90 V3 G11 K21 K23 I38 K43 D80 F82 2.7.11.1,2.7.11.27,2.7.11.31,2.7.11.26 P54645 GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDSHTIEFFEMCANLIKILAQ 4qfr B 3.34 BS01 32J A 1 V81 R83 T106 R107 D108 V113 I115 V3 R5 T28 R29 D30 V35 I37 P80386 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRDQNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKAPPILPPHLLQVILNKSCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 4qfr C 3.34 BS03 ADP C 1 R69 M84 T86 I87 T88 D89 Y120 P127 V129 I149 H150 R151 P153 R42 M57 T59 I60 T61 D62 Y93 P100 V102 I122 H123 R124 P126 P80385 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV 4qfs A 3.55 BS02 32H A 1 K29 K31 I46 K51 D88 F90 K21 K23 I38 K43 D80 F82 2.7.11.1,2.7.11.27,2.7.11.31,2.7.11.26 P54645 GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDSHTIEFFEMCANLIKILAQ 4qfs B 3.55 BS01 32H A 1 V81 R83 D108 V113 I115 V3 R5 D30 V35 I37 P80386 PTVFRWTGGGKEVYLSGSFNNWSKLPLTRDQNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKAPPILPPHLLQVILNKCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI 4qfs C 3.55 BS01 AMP C 1 H150 I203 A204 V224 S225 A226 H297 S313 S315 D316 H123 I160 A161 V181 S182 A183 H247 S258 S260 D261 P80385 YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITSLEELQIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLHETLEAIINRLVEAEVHRLVDVVKGIVSLSDILQALV 4qj1 A 2.42 BS01 IMP A 1 S48 M50 N191 G216 S217 I218 C219 D252 G254 M273 I274 G275 S276 Y299 G301 M302 G303 E329 G330 S47 M49 N148 G173 S174 I175 C176 D209 G211 M230 I231 G232 S233 Y256 G258 M259 G260 E272 G273 1.1.1.205 Q8T6T2 GTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 A 2.42 BS02 N09 A 1 A165 H166 T221 M302 G303 E329 A122 H123 T178 M259 G260 E272 1.1.1.205 Q8T6T2 GTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 A 2.42 BS03 N09 B 1 S354 G357 Y358 S297 G300 Y301 1.1.1.205 Q8T6T2 GTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 B 2.42 BS02 N09 B 1 S164 A165 H166 T221 M302 G303 M308 E329 S123 A124 H125 T180 M261 G262 M267 E275 1.1.1.205 Q8T6T2 AMGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 C 2.42 BS01 N09 B 3 S164 A165 H166 M302 G303 E329 S123 A124 H125 M261 G262 E275 1.1.1.205 Q8T6T2 AMGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 C 2.42 BS03 N09 D 1 L25 S354 G357 Y358 L26 S300 G303 Y304 1.1.1.205 Q8T6T2 AMGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 D 2.42 BS01 N09 A 1 P26 S354 G357 Y358 P28 S301 G304 Y305 1.1.1.205 Q8T6T2 NAMGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 D 2.42 BS02 IMP D 1 S48 M50 G216 S217 I218 C219 D252 G254 M273 G275 S276 Y299 G301 M302 G303 E329 G330 S50 M52 G176 S177 I178 C179 D212 G214 M233 G235 S236 Y259 G261 M262 G263 E276 G277 1.1.1.205 Q8T6T2 NAMGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qj1 D 2.42 BS03 N09 D 1 A165 H166 M302 G303 M308 E329 A125 H126 M262 G263 M268 E276 1.1.1.205 Q8T6T2 NAMGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSNKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYS 4qne A 2.32 BS01 IMP A 1 A49 M51 G304 S305 I306 C307 D340 G341 G342 M361 V362 G363 S364 Y387 G389 M390 G391 E417 G418 A45 M47 G174 S175 I176 C177 D210 G211 G212 M231 V232 G233 S234 Y257 G259 M260 G261 E271 G272 1.1.1.205 Q9KTW3 RIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKISGGLRVGAAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKAQFVRISGAGMKESHVHDVQITKEAPNYRL 4qne A 2.32 BS02 NAJ A 1 A228 D250 S251 S252 S256 V259 G300 I301 G302 C307 T309 M390 G391 E417 A98 D120 S121 S122 S126 V129 G170 I171 G172 C177 T179 M260 G261 E271 1.1.1.205 Q9KTW3 RIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKISGGLRVGAAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKAQFVRISGAGMKESHVHDVQITKEAPNYRL 4qne B 2.32 BS01 IMP B 1 A49 M51 G304 S305 I306 C307 T309 D340 G341 G342 M361 G363 S364 Y387 G389 M390 G391 E417 G418 A45 M47 G174 S175 I176 C177 T179 D210 G211 G212 M231 G233 S234 Y257 G259 M260 G261 E271 G272 1.1.1.205 Q9KTW3 RIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKISGGLRVGAAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKAQFVRISGAGMKESHVHDVQITKEAPNYRL 4qnr A 1.54 BS01 ATP A 1 N7 L8 L9 F15 E37 R38 G39 T40 G41 K42 E43 L44 I226 R227 N1 L2 L3 F9 E31 R32 G33 T34 G35 K36 E37 L38 I212 R213 P37344 25063294 NLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEARHPGRFERADGGTLFLDQLATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKR 4qnr A 1.54 BS02 MG A 1 E43 D107 E37 D93 P37344 25063294 NLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEARHPGRFERADGGTLFLDQLATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKR 4qos A 1.42 BS01 ADP A 1 L8 L9 F15 G39 T40 G41 K42 E43 L44 I226 R227 L1 L2 F8 G32 T33 G34 K35 E36 L37 I210 R211 P37344 25063294 LLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHERHPGRFERADGGTLFLDQLATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKR 4qqd A 2.28 BS01 36X A 1 D142 W151 E153 R209 M224 W238 F278 D10 W19 E21 R61 M76 W90 F130 6.3.2.- Q96T88 GLYKVNEYVDARDTNMGAWFEAQVVRVTRKEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIER 4qqd A 2.28 BS02 36X A 2 M148 F152 Y188 Y191 F237 M16 F20 Y40 Y43 F89 6.3.2.- Q96T88 GLYKVNEYVDARDTNMGAWFEAQVVRVTRKEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIER 4qqd B 2.28 BS01 36X B 1 D142 W151 R209 M224 W238 F278 D12 W21 R64 M79 W93 F133 6.3.2.- Q96T88 MWGLYKVNEYVDARDTNMGAWFEAQVVRVTRKLEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIE 4qqm A 1.78 BS01 III B 1 L92 Q96 A99 Q100 F125 W130 A133 F134 E158 L163 T166 D187 N189 G190 Y196 R199 Y224 L229 A232 L233 L1 Q5 A8 Q9 F34 W39 A42 F43 E67 L72 T75 D96 N98 G99 Y105 R108 Y133 L138 A141 L142 O14593 LSIHQLAAQGELDQLKEHLRKGDNLVNKPDERGFTPLIWASAFGEIETVRFLLEWGADPHILAKERESALSLASTGGYTDIVGLLLERDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVIENHILKLFQS 4qrn A 1.07 BS02 1DF A 1 E19 L47 Y51 R58 T90 S91 H188 A208 F212 H241 D314 Y317 E20 L48 Y52 R59 T91 S92 H189 A209 F213 H242 D315 Y318 Q2GA79 SMTQDLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATGIDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHTQGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGHMGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMDYPYQYVADEVRAMDAMDMSAQTKKKFFQTNAEKWFKL 4qrn A 1.07 BS03 1DF B 1 R252 M256 R253 M257 Q2GA79 SMTQDLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATGIDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHTQGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGHMGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMDYPYQYVADEVRAMDAMDMSAQTKKKFFQTNAEKWFKL 4qro A 1.65 BS01 MN A 1 E8 H10 H164 D287 E8 H10 H164 D287 Q12BV1 MNGKIALEEHFATEETLMDSAGFVPDKDWPELRSRLLDIQDRRVRLMDEHGIETMILSLNAPAVQAIADSTRANETARRANDFLAEQVAKQPTRFRGFAALPMQDPELAARELERCVKELGFVGALVNGFSQDNRSAVPLYYDMAQYWPFWETVQALDVPFYLHPRNPLPSDARIYDGHAWLLGPTWAFGQETAVHALRLMGSGLFDKYPALKIILGHMGEGLPYSMWRIDHRNAWIKTTPKYPAKRKIVDYFNENFYLTTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHAADWFENTSISEADRKKIGWGNAQNLFKLNRAENLYF 4qro A 1.65 BS02 38L A 1 E8 H10 F23 H164 P185 F189 H218 D287 F290 E8 H10 F23 H164 P185 F189 H218 D287 F290 Q12BV1 MNGKIALEEHFATEETLMDSAGFVPDKDWPELRSRLLDIQDRRVRLMDEHGIETMILSLNAPAVQAIADSTRANETARRANDFLAEQVAKQPTRFRGFAALPMQDPELAARELERCVKELGFVGALVNGFSQDNRSAVPLYYDMAQYWPFWETVQALDVPFYLHPRNPLPSDARIYDGHAWLLGPTWAFGQETAVHALRLMGSGLFDKYPALKIILGHMGEGLPYSMWRIDHRNAWIKTTPKYPAKRKIVDYFNENFYLTTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHAADWFENTSISEADRKKIGWGNAQNLFKLNRAENLYF 4qro A 1.65 BS03 38L B 1 R229 N234 R229 N234 Q12BV1 MNGKIALEEHFATEETLMDSAGFVPDKDWPELRSRLLDIQDRRVRLMDEHGIETMILSLNAPAVQAIADSTRANETARRANDFLAEQVAKQPTRFRGFAALPMQDPELAARELERCVKELGFVGALVNGFSQDNRSAVPLYYDMAQYWPFWETVQALDVPFYLHPRNPLPSDARIYDGHAWLLGPTWAFGQETAVHALRLMGSGLFDKYPALKIILGHMGEGLPYSMWRIDHRNAWIKTTPKYPAKRKIVDYFNENFYLTTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHAADWFENTSISEADRKKIGWGNAQNLFKLNRAENLYF 4qro F 1.65 BS03 38L F 1 E8 H10 F23 H164 P185 H218 D287 F290 E8 H10 F23 H164 P185 H218 D287 F290 Q12BV1 MNGKIALEEHFATEETLMDSAGFVPDKDWPELRSRLLDIQDRRVRLMDEHGIETMILSLNAPAVQAIADSTRANETARRANDFLAEQVAKQPTRFRGFAALPMQDPELAARELERCVKELGFVGALVNGFSQDNRSAVPLYYDMAQYWPFWETVQALDVPFYLHPRNPLPSDARIYDGHAWLLGPTWAFGQETAVHALRLMGSGLFDKYPALKIILGHMGEGLPYSMWRIDHRNAWIKTTPKYPAKRKIVDYFNENFYLTTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHAADWFENTSISEADRKKIGWGNAQNLFKL 4qro G 1.65 BS03 BCT G 1 D172 Q191 D172 Q191 Q12BV1 MNGKIALEEHFATEETLMDSAGFVPDKDWPELRSRLLDIQDRRVRLMDEHGIETMILSLNAPAVQAIADSTRANETARRANDFLAEQVAKQPTRFRGFAALPMQDPELAARELERCVKELGFVGALVNGFSQDNRSAVPLYYDMAQYWPFWETVQALDVPFYLHPRNPLPSDARIYDGHAWLLGPTWAFGQETAVHALRLMGSGLFDKYPALKIILGHMGEGLPYSMWRIDHRNAWIKTTPKYPAKRKIVDYFNENFYLTTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHAADWFENTSISEADRKKIGWGNAQNLFKLLYF 4qs5 A 1.80 BS01 MN A 1 E19 H188 N314 E17 H186 N312 Q2GA79 QDLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATGIDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHTQGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGHMGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMNYPYQYVADEVRAMDAMDMSAQTKKKFFQTNAEKWFKL 4qs5 A 1.80 BS02 1DF A 1 E19 L47 Y51 T90 S91 H188 F212 H241 N314 Y317 E17 L45 Y49 T88 S89 H186 F210 H239 N312 Y315 Q2GA79 QDLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATGIDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHTQGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGHMGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMNYPYQYVADEVRAMDAMDMSAQTKKKFFQTNAEKWFKL 4qs5 C 1.80 BS02 1DF C 1 E19 Y51 T90 S91 H188 A208 F212 H241 N314 Y317 E16 Y48 T87 S88 H185 A205 F209 H238 N311 Y314 Q2GA79 DLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATGIDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHTQGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGHMGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMNYPYQYVADEVRAMDAMDMSAQTKKKFFQTNAEKWFKL 4qs5 D 1.80 BS03 1DF D 1 E19 Y51 T90 S91 H188 F212 H241 N314 Y317 E16 Y48 T87 S88 H185 F209 H238 N311 Y314 Q2GA79 DLKTGGEQGYLRIATEEAFATREIIDVYLRMIRDGTADKGMVSLWGFYAQSPSERATQILERLLDLGERRIADMDATGIDKAILALTSPGVQPLHDLDEARTLATRANDTLADACQKYPDRFIGMGTVAPQDPEWSAREIHRGARELGFKGIQINSHTQGRYLDEEFFDPIFRALVEVDQPLYIHPATSPDSMIDPMLEAGLDGAIFGFGVETGMHLLRLITIGIFDKYPSLQIMVGHMGEALPYWLYRLDYMHQAGVRSQRYERMKPLKKTIEGYLKSNVLVTNSGVAWEPAIKFCQQVMGEDRVMYAMNYPYQYVADEVRAMDAMDMSAQTKKKFFQTNAEKWFKL 4qsd A 1.34 BS01 SUC A 1 L36 D37 Q41 D89 N142 E195 E196 F199 Q245 W265 G297 D298 Y299 R367 L9 D10 Q14 D62 N115 E168 E169 F172 Q218 W238 G270 D271 Y272 R340 A9CGI0 DVTLTLWSLDRDIQPAPNLIKEFNALNNGIKIEYRQLQFDDVVSESMRAYSTGNAPDIIAIDNPNHAMFASRGAFLDVTDMIAKSDVIKTENYFPGPLKSVTWDGKYFGVPKATNTIALYYNKDLFKAAGLDAAKPPQTWDELVDAARKLTNPAKNVYGISFSAKANEEGTFQFLPWAQMAGATYKNINTDGAVKALETWKTLLDEKLASPDTLTRSQWDSTATFNAGNAAMAISGPWEIDRMLKDAKFDWGVTLLPVPTPDAPRSSAMGDYNWAIFSKTKHPAEAFKAIEFFASKDKDMFKNFGQLPARSDIPVPPTGNALKDEALKTFVEQLKYAQPRGPSPEWPKISKAIQDAIQGALSGQMTPKAALDQAAEKIKLVD 4qsd A 1.34 BS02 3CK A 1 L36 Q41 D89 N142 E195 E196 F199 Q245 W265 G297 D298 Y299 R367 L9 Q14 D62 N115 E168 E169 F172 Q218 W238 G270 D271 Y272 R340 A9CGI0 DVTLTLWSLDRDIQPAPNLIKEFNALNNGIKIEYRQLQFDDVVSESMRAYSTGNAPDIIAIDNPNHAMFASRGAFLDVTDMIAKSDVIKTENYFPGPLKSVTWDGKYFGVPKATNTIALYYNKDLFKAAGLDAAKPPQTWDELVDAARKLTNPAKNVYGISFSAKANEEGTFQFLPWAQMAGATYKNINTDGAVKALETWKTLLDEKLASPDTLTRSQWDSTATFNAGNAAMAISGPWEIDRMLKDAKFDWGVTLLPVPTPDAPRSSAMGDYNWAIFSKTKHPAEAFKAIEFFASKDKDMFKNFGQLPARSDIPVPPTGNALKDEALKTFVEQLKYAQPRGPSPEWPKISKAIQDAIQGALSGQMTPKAALDQAAEKIKLVD 4qsd A 1.34 BS03 SUC A 2 L158 D159 K162 P163 P164 Q165 E169 L131 D132 K135 P136 P137 Q138 E142 A9CGI0 DVTLTLWSLDRDIQPAPNLIKEFNALNNGIKIEYRQLQFDDVVSESMRAYSTGNAPDIIAIDNPNHAMFASRGAFLDVTDMIAKSDVIKTENYFPGPLKSVTWDGKYFGVPKATNTIALYYNKDLFKAAGLDAAKPPQTWDELVDAARKLTNPAKNVYGISFSAKANEEGTFQFLPWAQMAGATYKNINTDGAVKALETWKTLLDEKLASPDTLTRSQWDSTATFNAGNAAMAISGPWEIDRMLKDAKFDWGVTLLPVPTPDAPRSSAMGDYNWAIFSKTKHPAEAFKAIEFFASKDKDMFKNFGQLPARSDIPVPPTGNALKDEALKTFVEQLKYAQPRGPSPEWPKISKAIQDAIQGALSGQMTPKAALDQAAEKIKLVD 4qvu A 2.65 BS01 ZN A 1 H152 C177 E180 H116 C141 E144 Q73EW7 DILATEGSIIWLKNKFPTLKDTFQTVLIETDNCEDHIATYTEEHMRSLIRFSIKHWLNLQKNEEFTSVILYKNHGPFSGGSLHHAHMQIIGMKYVNYLDNVEQDNFQGVIVQKNEHIELNISDRPIIGFTEFNIIIEDIGCIDELANYIQQTVRYILTDFHKGCSSYNLFFYYLNEKIICKVVPRFVVSPLYVGYKIPQVSTKIEDVKIQLAAYFTK 4qxd B 2.55 BS02 MG B 2 E68 D106 D109 D223 E68 D106 D109 D223 3.1.3.57 C4M633 MQTSLFEFANVLITAVKEASYSISKFKEEVEIKYKSDGSEVTQVDTQSQQIIFSIIKNKYPTINIIGEEDVENGIPDNQLPTITQLSFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCVLVGVTYKGKPMIGIVSKPFYNNEITFAIENYISSISLQPLNDKIIFVCSKKNDIQHLIKSFPDPYEVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQVILEAQGGIVCDIYGNPLCYPSSKKESMRHKKGVLCLSPRAKKYLPYMLSISKTILLLQHH 4tqt A 2.15 BS01 ZN A 1 H61 H63 K151 D317 H56 H58 K146 D312 3.5.2.2 Q8G2P0 ASKVIKGGTVITADRTFRADILIEDGKIAAIGDSLEGDEVIDASGCYVMPGGIDPHTHLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKAGKARTDYSFHMAITGWNERTFNEMAEVVKRGINTFKHFMAYKGALMVNDDEMFASFQRCAELGAMPLVHAENGDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPFRDKLNQDSLWAGLAAGSLQCVATDHCAFTTEQKRYGIGNFTKIPNGTGGLEERMPVLWTRGVRTGRLTPNEFVAVTSTNIAKILNIYPQKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNVFEGFELKGLPIMTLSRGRIAFDKGQVTAKPGDGRFIEREPNGAVNRALSQWKEIVAPRKVERSA 4tqt A 2.15 BS02 ZN A 2 K151 H184 H240 K146 H179 H235 3.5.2.2 Q8G2P0 ASKVIKGGTVITADRTFRADILIEDGKIAAIGDSLEGDEVIDASGCYVMPGGIDPHTHLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKAGKARTDYSFHMAITGWNERTFNEMAEVVKRGINTFKHFMAYKGALMVNDDEMFASFQRCAELGAMPLVHAENGDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPFRDKLNQDSLWAGLAAGSLQCVATDHCAFTTEQKRYGIGNFTKIPNGTGGLEERMPVLWTRGVRTGRLTPNEFVAVTSTNIAKILNIYPQKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNVFEGFELKGLPIMTLSRGRIAFDKGQVTAKPGDGRFIEREPNGAVNRALSQWKEIVAPRKVERSA 4tsf A 3.20 BS01 ATP A 1 Q172 T173 G174 K175 T176 S177 F357 R362 P363 Q430 Q432 Q149 T150 G151 K152 T153 S154 F334 R339 P340 Q405 Q407 P19483 25049402 DLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKARRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVISQHQALLGKIRTDGKISEESDAKLKEIVTNFLAGFEA 4tsf D 3.20 BS01 ADP D 1 G157 G159 G161 K162 T163 V164 Y345 F418 F424 T425 G149 G151 G153 K154 T155 V156 Y337 F410 F416 T417 3.6.3.14 P00829 25049402 TTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEH 4tsf E 3.20 BS01 III H 1 M393 K401 V404 S405 R408 R412 D450 H451 L452 E454 Q455 L473 A474 H477 M385 K393 V396 S397 R400 R404 D442 H443 L444 E446 Q447 L465 A466 H469 3.6.3.14 P00829 25049402 TTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS 4tsf F 3.20 BS02 ADP F 1 G157 G159 V160 G161 K162 T163 V164 Y345 F418 G149 G151 V152 G153 K154 T155 V156 Y337 F410 3.6.3.14 P00829 25049402 TTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLA 4tt3 B 3.21 BS01 III I 1 E399 V400 E384 V385 P19483 25049402 ILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKARRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVADAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVISQHQALLGKIRTDGKISEESDAKLKEIVTNFLAGFEA 4tt3 E 3.21 BS01 III J 1 M393 K401 V404 S405 R408 D450 H451 L452 P453 A474 E475 E476 M386 K394 V397 S398 R401 D443 H444 L445 P446 A467 E468 E469 3.6.3.14 P00829 25049402 ATTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEH 4tt3 F 3.21 BS01 III I 1 Y381 Q385 I388 A389 M393 K401 V404 S405 R408 R412 D450 H451 L452 P453 E454 A470 L473 A474 H477 Y373 Q377 I380 A381 M385 K393 V396 S397 R400 R404 D442 H443 L444 P445 E446 A462 L465 A466 H469 3.6.3.14 P00829 25049402 TTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEH 4tt3 F 3.21 BS03 ADP F 1 G157 G159 V160 G161 K162 T163 V164 Y345 F418 F424 G149 G151 V152 G153 K154 T155 V156 Y337 F410 F416 3.6.3.14 P00829 25049402 TTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEH 4tt3 G 3.21 BS01 III I 1 K237 N238 E241 M242 K245 K148 N149 E152 M153 K156 P05631 25049402 ATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPASDRGLCGAIHSSVAKQMKSVGDKIRSILHRTHSDQFLTFKEVGRRPPTFGDASVIALELLNSGYRFRSVISYKTQEYSLANIIYYSLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAAL 4tth B 2.90 BS01 24V B 1 I19 V27 A41 V77 F98 E99 V101 D102 D104 T107 Q149 L152 A162 I5 V9 A22 V54 F68 E69 V71 D72 D74 T77 Q119 L122 A132 2.7.11.22 Q00534 24641103 CVAEIGEKVFKARDLKNGRFVALKRVRVEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTTKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPPIEKFDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 4tv3 A 2.85 BS01 ML9 A 1 R770 M772 I800 K802 D810 Y836 I848 E849 V851 Q859 M922 I932 D933 R627 M629 I657 K659 D667 Y693 I705 E706 V708 Q716 M772 I782 D783 2.7.1.153,2.7.11.1 P42336 25043846 NREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRKSLWVINSALRIKILCATYVNVNDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDRVPFVLTQDFLIVISTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDA 4twk A 2.60 BS01 K A 1 T142 I143 T251 I252 T105 I106 T206 I207 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS02 K A 2 I143 G144 F145 G146 I252 G253 G255 I106 G107 F108 G109 I207 G208 G210 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS03 37X A 1 W295 V298 I299 E302 W244 V247 I248 E251 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS04 37X A 2 K191 T195 K154 T158 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS05 37X A 3 D179 L181 G182 T183 G186 I189 S210 T211 Y284 M291 D142 L144 G145 T146 G149 I152 S173 T174 Y233 M240 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS06 37X A 4 I215 M291 W295 V298 I178 M240 W244 V247 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS07 MG A 1 G113 H126 G260 G76 H89 G215 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS08 K B 1 T142 I143 G144 T251 I252 G253 T105 I106 G107 T206 I207 G208 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk A 2.60 BS09 37X B 1 Q105 I106 A108 A112 I114 P116 R151 Q68 I69 A71 A75 I77 P79 R114 O95069 TINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPGWSALDAIYFVVITLTTIGFGDYVAGGSDIKPVVWFWILVGLAYFAAVLSMIGDWLRVISAENLYF 4twk B 2.60 BS02 K A 3 I143 G144 F145 I252 I95 G96 F97 I204 O95069 MKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYKPVVWFWILVGLAYFAAVLSMIGDWLRVISAE 4twk B 2.60 BS04 37X B 1 Q76 T79 I80 Q83 K84 Q35 T38 I39 Q42 K43 O95069 MKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYKPVVWFWILVGLAYFAAVLSMIGDWLRVISAE 4tx6 A 1.90 BS01 38B A 1 Y34 G123 A124 D172 E174 Q230 Y232 W312 Y6 G95 A96 D144 E146 Q202 Y204 W284 B0Y2Y2 25063338 SNLAIYWGQGPNQLRLSHFCQETSLDIINIGFINYFPDMSPGHWPGSNFGNQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGGFGYATMVNTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAKSFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASETAANQGYYLTPDEVESLVSTYMDRYPDTFGGIMLWEATASENNQIDGAPYADHMKDILLH 4tx6 B 1.90 BS01 38B B 1 Y34 F60 G123 A124 D172 E174 Q230 Y232 W312 Y7 F33 G96 A97 D145 E147 Q203 Y205 W285 B0Y2Y2 25063338 RSNLAIYWGQGPNQLRLSHFCQETSLDIINIGFINYFPDMSPGHWPGSNFGNQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGGFGYATMVNTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAKSFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASETAANQGYYLTPDEVESLVSTYMDRYPDTFGGIMLWEATASENNQIDGAPYADHMKDILLH 4tx9 A 1.60 BS01 AMZ A 1 G27 V56 L58 A61 F62 S85 G86 G87 R89 G108 T109 D134 G144 W145 G28 V57 L59 A62 F63 S86 G87 G88 R90 G109 T110 D135 G145 W146 B5I4P8 AMPSKLSRLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALSWQRAGAEWLHLVDLDAAFGTGDNRELVRQVTEAMDIKVELSGGIRDDASLAAALATGCTRVNLGTAALESPEWVAKVIAEHGDRIAVGLDVRGTTLKGRGWTSEGGDLYEALERLDKEGCARYVVTDIAKDGTLQGPNLELLRNVCAATDRPVVASGGVSSLDDLRAIAELVPLGVEGSIVGKALYAKAFTLEEALEAVAQ 4txe A 1.80 BS01 38F A 1 Y32 Q35 F60 A110 D155 E157 A187 F210 Q212 Y214 G247 W285 Y8 Q11 F36 A86 D131 E133 A163 F186 Q188 Y190 G223 W261 3.2.1.14 P29029 25063338 ANTNIAVYWGQNSAGTQESLATYCESSDADIFLLSFLNQFPTLGLNFANACSDTFSDGLLHCTQIAEDIETCQSLGKKVLLSLGGASGSYLFSDDSQAETFAQTLWDTFGEGTGASERPFDSAVVDGFDFDIENNNEVGYSALATKLRTLFAEGTKQYYLSAAPQCPYPDASVGDLLENADIDFAFIQFYNNYCSVSGQFNWDTWLTYAQTVSPNKNIKLFLGLPGSASAAGSGYISDTSLLESTIADIASSSSFGGIALWDASQAFSNELNGEPYVEILKNLLTSAS 4txt A 2.00 BS01 CT3 A 1 H41 E49 A50 E60 W417 W423 T497 D498 R618 W620 H31 E39 A40 E50 W407 W413 T487 D488 R608 W610 B9MKU7 LGEYGQRFMWLWNKIHDPANGYFNQDGIPYHSVETLICEAPDYGHLTTSEAFSYYVWLEAVYGKLTGDWSKFKTAWDTLEKYMIPSAEDQPMRSYDPNKPATYAGEWETPDKYPSPLEFNVPVGKDPLHNELVSTYGSTLMYGMHWLMDVDNWYGYGKRGDGVSRASFINTFQRGPEESVWETVPHPSWEEFKWGGPNGFLDLFIKDQNYSKQWRYTDAPDADARAIQATYWAKVWAKEQGKFNEISSYVAKAAKMGDYLRYAMFDKYFKPLGCQDKNAAGGTGYDSAHYLLSWYYAWGGALDGAWSWKIGSSHVHFGYQNPMAAWALANDSDMKPKSPNGASDWAKSLKRQIEFYRWLQSAEGAIAGGATNSWNGRYEKYPAGTATFYGMAYEPNPVYHDPGSNTWFGFQAWSMQRVAEYYYVTGDKDAGALLEKWVSWVKSVVKLNSDGTFAIPSTLDWSGQPDTWNGAYTGNSNLHVKVVDYGTDLGITASLANALLYYSAGTKKYGVFDEGAKNLAKELLDRMWKLYRDEKGLSAPEKRADYKRFFEQEVYIPAGWIGKMPNGDVIKSGVKFIDIRSKYKQDPDWPKLEAAYKSGQAPEFRYHRFWAQCDIAIANATYEILFG 4tz4 C 3.01 BS02 LVY C 1 N351 P352 H353 H378 S379 W380 W386 W400 F402 N284 P285 H286 H311 S312 W313 W319 W333 F335 Q96SW2 NFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSEAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPD 4tzc C 1.88 BS01 ZN C 1 C325 C328 C393 C396 C6 C9 C60 C63 Q8C7D2 STSLCCKQCQETEITTKNEIFSLSVHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP 4tzc C 1.88 BS02 EF2 C 1 H380 S381 W382 W388 W402 F404 H47 S48 W49 W55 W69 F71 Q8C7D2 STSLCCKQCQETEITTKNEIFSLSVHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP 4tzc B 1.88 BS02 EF2 B 1 H380 S381 W382 W388 W402 F404 H53 S54 W55 W61 W75 F77 Q8C7D2 TSLCCKQCQETEITTKNEIFSLSLCGPMGYVHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPT 4u5t A 3.30 BS01 3CG A 1 R20 R27 R19 R26 22851716 DPDLEIRAAFLEKENTALRTEVAELRKEVGRCKNIVS