3w8k A 1.50 BS01 ZN A 1 V278 H351 V270 H339 3.5.2.6 Q51578 DPLRPVVDASIQPLLKEHRIPGMAVAVLKDGKAHYFNYGVANRESGASVSEQTLFEIGSVSKTLTATLGAYAVVKGAMQLDDKASRHAPWLKGSVFDSITMGELATYSAGGLPLQFPEEVDSSEKMRAYYRQWAPVYSPGSHRQYSNPSIGLFGHLAASSLKQPFAQLMEQTLLPGLGMHHTYVNVPKQAMASYAYGYSKEDKPIRVGMLADEAYGIKTSSADLLAFVKANIGGVDDKALQQAISLTHKGHYSVGGMTQGLGWESYAYPVTEQTLLAGNSAKVILEANPTAAPRQVLFNKTGSSNGFGAYVAFVPARGIGIVMLANRNYPIPARVKAAHAILAQLAG 3w8k A 1.50 BS02 ZN A 2 H187 D231 H181 D223 3.5.2.6 Q51578 DPLRPVVDASIQPLLKEHRIPGMAVAVLKDGKAHYFNYGVANRESGASVSEQTLFEIGSVSKTLTATLGAYAVVKGAMQLDDKASRHAPWLKGSVFDSITMGELATYSAGGLPLQFPEEVDSSEKMRAYYRQWAPVYSPGSHRQYSNPSIGLFGHLAASSLKQPFAQLMEQTLLPGLGMHHTYVNVPKQAMASYAYGYSKEDKPIRVGMLADEAYGIKTSSADLLAFVKANIGGVDDKALQQAISLTHKGHYSVGGMTQGLGWESYAYPVTEQTLLAGNSAKVILEANPTAAPRQVLFNKTGSSNGFGAYVAFVPARGIGIVMLANRNYPIPARVKAAHAILAQLAG 3wez A 2.11 BS01 N8V A 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 W273 L274 H276 Y306 N321 Y333 Y485 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 W245 L246 H248 Y278 N293 Y305 Y457 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf3 A 2.15 BS01 NAG A 1 N247 T249 D250 N219 T221 D222 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf3 A 2.15 BS02 GAL A 1 Y83 I126 C127 A128 E129 N187 E188 E268 Y270 L274 Y306 Y333 Y55 I98 C99 A100 E101 N159 E160 E240 Y242 L246 Y278 Y305 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wf3 B 2.15 BS01 NAG B 1 W527 M553 N555 P613 W499 M511 N513 P571 3.2.1.23 P16278 QRMFEIDYSRDSFLKDGQPFRYTSGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSS 3wip F 2.60 BS02 ACH J 1 R104 M114 R104 M114 P58154 24637639 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTEDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEI 3wip H 2.60 BS01 ACH G 1 R104 L112 R102 L110 P58154 24637639 LDRADILYNIRQTSRPDVIPTQRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3wip I 2.60 BS01 ACH I 1 W143 Y185 Y192 W143 Y181 Y188 P58154 24637639 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3wky A 1.80 BS01 CUO A 1 F72 H199 H203 H226 H357 H361 F393 H397 F61 H188 H192 H215 H346 H350 F382 H386 G5EKM4 24720693 DEELRQLFYLPYESTSTLADRLGIQLPPLELSTAVTVLDPELKAKLGSALSIPEGIPFFAFNKQHSQAVKDLSKVFIEAKSLNVLKDVAIMVKDHVNSAVFLAALYHTYYERKDLSPGDTPPLPTVLPDRFVPTFIINKAKKLAKSAIINNQTEVVVEWHSDETGLSSRSPEHRVSYWREDMNLNSFHWHWHLSNPYYIEPGDRDRRGELFYYMHHNLVARYNMERLSLNLKPVKAFEDWRIPVQDGYFPHLTTGNGQEWSSRQDSTFFQDIREIPLVDSNYVSQLEMWRTHLYHGIDVGYLIHENGSYVRLTDNPEVGEDYGINLVGEALEAGDSVNPDVYGNIHNLGHDFLGQSHDPAKKHSTTSGVMGAVETAVRDPVFFRWHKFIDNVFHRYKLTQPPYTPRQLSGNITVLNVTVQEEHWIDDYVSPENLLHTFFTPKTFNSSSGIDFRLKRDDNITVHIKSNFLEHPDFSYTITVNNPTSDFKRMKLRIFLAPKFDEEGVKMNYASLLRYWTEVDVFETDPIAPGIAYITRHSNESSILSTTAFAFSGCSWPRNLQVPRGTQDGMNFHFFVMATDVSSSSFCGRPDQPIPDPWPMGYPLERRSSKATIEDFVDEHPNMMLQEVTITHLRDPSSVLRRPISERKECLLFTC 3wky B 1.80 BS02 MG B 1 A247 F248 E249 D250 A237 F238 E239 D240 G5EKM4 24720693 DEELRQLFYLPYESTSTLADRLGIQLPPLELSPTAVTVLDPELKAKLGSALSIPEGIPFFAFNKQHSQAVKDLSKVFIEAKSLNVLKDVAIMVKDHVNSAVFLAALYHTYYERKDLSPGDTPPLPTVLPDRFVPTFIINKAKKLAKSAIINNQTEVVVEWHSDETGLSSRSPEHRVSYWREDMNLNSFHWHWHLSNPYYIEPGDRDRRGELFYYMHHNLVARYNMERLSLNLKPVKAFEDWRIPVQDGYFPHLTTGNGQEWSSRQDSTFFQDIREIPLVDSNYVSQLEMWRTHLYHGIDVGYLIHENGSYVRLTDNPEVGEDYGINLVGEALEAGDSVNPDVYGNIHNLGHDFLGQSHDPAKKHSTTSGVMGAVETAVRDPVFFRWHKFIDNVFHRYKLTQPPYTPRQLSGNITVLNVTVQEEHWIDDYVSPENLLHTFFTPKTFNSSSGIDFRLKRDDNITVHIKSNFLEHPDFSYTITVNNPTSDFKRMKLRIFLAPKFDEEGVKMNYASLLRYWTEVDVFETDPIAPGIAYITRHSNESSILSTTAFAFSGCSWPRNLQVPRGTQDGMNFHFFVMATDVSSSFCGRPDQPIPDPWPMGYPLERRSSKATIEDFVDEHPNMMLQEVTITHLRDPSSVLRRPISERKECLLFTC 3wq5 A 1.80 BS01 VPA A 1 Q53 H157 W158 N202 E203 W205 S206 Y345 F389 E416 W463 E470 W471 S473 Q477 F479 Q21 H125 W126 N170 E171 W173 S174 Y313 F357 E384 W431 E438 W439 S441 Q445 F447 3.2.1.149 Q7X9A9 SFNRTSFPDGFVFGAASSAYQFEGAAKEGGKGPNIWDTFTHEFPGKISNGSTGDVADDFYHRYKEDVKVLKFIGLDGFRMSISWARVLPRGKLSGGVNKEGIAFYNNVINDLLSKGIQPFITIFHWDLPQALEDEYGGFLSPHIVNDFRDFAELCFKEFGDRVKHWITMNEPWSYSYGGYDAGLLAPGRCSAFMAFCPKGNSGTEPYIVTHNLLLSHAAAVKLYKEKYQAYQKGQIGITLVTYWMIPYSNSKADKDAAQRALDFMYGWFIEPLSFGEYPKSMRRLVGKRLPRFTKEQAMLVKGSFDFLGLNYYIANYVLNVPTSNSVNLSYTTDSLSNQTAFRNGVAIGRPTGVPAFFMYPKGLKDLLVYTKEKYNDPVIYITENGMGDNNNVTTEEGIKDPQRVYFYNQHLLSLKNAIAAGVKVKGYFTWAFLDNFEWLSGYTQRFGIVYVDFKDGLKRYPKHSALWFKKFLLK 3wq5 A 1.80 BS02 VPA A 2 A58 K59 K63 G64 P65 D69 P121 R122 A163 A26 K27 K31 G32 P33 D37 P89 R90 A131 3.2.1.149 Q7X9A9 SFNRTSFPDGFVFGAASSAYQFEGAAKEGGKGPNIWDTFTHEFPGKISNGSTGDVADDFYHRYKEDVKVLKFIGLDGFRMSISWARVLPRGKLSGGVNKEGIAFYNNVINDLLSKGIQPFITIFHWDLPQALEDEYGGFLSPHIVNDFRDFAELCFKEFGDRVKHWITMNEPWSYSYGGYDAGLLAPGRCSAFMAFCPKGNSGTEPYIVTHNLLLSHAAAVKLYKEKYQAYQKGQIGITLVTYWMIPYSNSKADKDAAQRALDFMYGWFIEPLSFGEYPKSMRRLVGKRLPRFTKEQAMLVKGSFDFLGLNYYIANYVLNVPTSNSVNLSYTTDSLSNQTAFRNGVAIGRPTGVPAFFMYPKGLKDLLVYTKEKYNDPVIYITENGMGDNNNVTTEEGIKDPQRVYFYNQHLLSLKNAIAAGVKVKGYFTWAFLDNFEWLSGYTQRFGIVYVDFKDGLKRYPKHSALWFKKFLLK 3wq6 A 1.80 BS01 ZPA A 1 Q53 H157 W158 N202 E203 W205 S206 Y209 L217 Y275 Y345 F389 E416 W463 E470 W471 L472 S473 Q477 F479 Q22 H126 W127 N171 E172 W174 S175 Y178 L186 Y244 Y314 F358 E385 W432 E439 W440 L441 S442 Q446 F448 3.2.1.149 Q7X9A9 SSFNRTSFPDGFVFGAASSAYQFEGAAKEGGKGPNIWDTFTHEFPGKISNGSTGDVADDFYHRYKEDVKVLKFIGLDGFRMSISWARVLPRGKLSGGVNKEGIAFYNNVINDLLSKGIQPFITIFHWDLPQALEDEYGGFLSPHIVNDFRDFAELCFKEFGDRVKHWITMNEPWSYSYGGYDAGLLAPGRCSAFMAFCPKGNSGTEPYIVTHNLLLSHAAAVKLYKEKYQAYQKGQIGITLVTYWMIPYSNSKADKDAAQRALDFMYGWFIEPLSFGEYPKSMRRLVGKRLPRFTKEQAMLVKGSFDFLGLNYYIANYVLNVPTSNSVNLSYTTDSLSNQTAFRNGVAIGRPTGVPAFFMYPKGLKDLLVYTKEKYNDPVIYITENGMGDNNNVTTEEGIKDPQRVYFYNQHLLSLKNAIAAGVKVKGYFTWAFLDNFEWLSGYTQRFGIVYVDFKDGLKRYPKHSALWFKKFLL 3wq6 A 1.80 BS02 FUC A 1 F34 S38 K448 F3 S7 K417 3.2.1.149 Q7X9A9 SSFNRTSFPDGFVFGAASSAYQFEGAAKEGGKGPNIWDTFTHEFPGKISNGSTGDVADDFYHRYKEDVKVLKFIGLDGFRMSISWARVLPRGKLSGGVNKEGIAFYNNVINDLLSKGIQPFITIFHWDLPQALEDEYGGFLSPHIVNDFRDFAELCFKEFGDRVKHWITMNEPWSYSYGGYDAGLLAPGRCSAFMAFCPKGNSGTEPYIVTHNLLLSHAAAVKLYKEKYQAYQKGQIGITLVTYWMIPYSNSKADKDAAQRALDFMYGWFIEPLSFGEYPKSMRRLVGKRLPRFTKEQAMLVKGSFDFLGLNYYIANYVLNVPTSNSVNLSYTTDSLSNQTAFRNGVAIGRPTGVPAFFMYPKGLKDLLVYTKEKYNDPVIYITENGMGDNNNVTTEEGIKDPQRVYFYNQHLLSLKNAIAAGVKVKGYFTWAFLDNFEWLSGYTQRFGIVYVDFKDGLKRYPKHSALWFKKFLL 3wss A 2.15 BS01 SAH A 1 F33 M36 R42 I71 G72 T73 G74 L78 L93 E94 V95 R122 S123 E140 V141 T154 F13 M16 R22 I51 G52 T53 G54 L58 L73 E74 V75 R102 S103 E120 V121 T134 2.1.1.- Q9XW42 24726727 DYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 3wst D 2.39 BS01 SAH D 1 M36 R42 I71 G72 T73 L78 E94 V95 E121 R122 S123 E140 V141 T154 M36 R42 I71 G72 T73 L78 E94 V95 E121 R122 S123 E133 V134 T147 2.1.1.- Q9XW42 24726727 MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 3wst B 2.39 BS01 SAH B 1 F33 M36 R42 I71 G72 T73 G74 L78 E94 V95 R122 S123 E140 T154 F33 M36 R42 I71 G72 T73 G74 L78 E94 V95 R122 S123 E134 T148 2.1.1.- Q9XW42 24726727 MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 3wst M 2.39 BS01 SAH M 1 F33 M36 R42 I71 G72 T73 G74 T75 L78 L93 E94 V95 E121 R122 S123 E140 T154 F33 M36 R42 I71 G72 T73 G74 T75 L78 L91 E92 V93 E119 R120 S121 E133 T147 2.1.1.- Q9XW42 24726727 MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREDKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 3wst O 2.39 BS01 SAH O 1 F33 M36 R42 I71 G72 T73 G74 L93 E94 V95 E121 R122 S123 E140 V141 T154 F33 M36 R42 I71 G72 T73 G74 L93 E94 V95 E121 R122 S123 E137 V138 T151 2.1.1.- Q9XW42 24726727 MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVSQSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 3wst R 2.39 BS01 SAH R 1 M36 R42 G72 T73 G74 L78 E94 V95 E121 R122 S123 E140 T154 M36 R42 G72 T73 G74 L78 E94 V95 E121 R122 S123 E134 T148 2.1.1.- Q9XW42 24726727 MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 3wst J 2.39 BS01 SAH J 1 M36 R42 G72 T73 L78 E94 V95 R122 S123 E140 V141 T154 M36 R42 G72 T73 L78 E94 V95 R122 S123 E140 V141 T154 2.1.1.- Q9XW42 24726727 MFLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMSSSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKS 4bhm A 2.70 BS01 NUC G 1 S60 F62 K63 F67 N69 R71 Y74 P82 G83 K84 G88 T90 Q93 S23 F25 K26 F30 N32 R34 Y37 P45 G46 K47 G51 T53 Q56 G4NEJ8 GSQVDAEGNPFWEISDKRRVGISQFKKMDFINIREYYEAGGEMKPGKKGIGLTVDQYTAFLKAIPAINAELRSRGHDIT 4bhm A 2.70 BS02 NUC H 1 D53 R55 D16 R18 G4NEJ8 GSQVDAEGNPFWEISDKRRVGISQFKKMDFINIREYYEAGGEMKPGKKGIGLTVDQYTAFLKAIPAINAELRSRGHDIT 4bhm B 2.70 BS01 NUC G 1 S52 R55 E72 S14 R17 E34 G4NEJ8 SQVDAEGNPFWEISDKRRVGISQFKKMDFINIREYYEAGEMKPGKKGIGLTVDQYTAFLKAIPAINAELRSRGHDIT 4bhm C 2.70 BS01 NUC I 1 S60 F62 N69 R71 Y74 P82 G83 K84 T90 Q93 S23 F25 N32 R34 Y37 P45 G46 K47 T53 Q56 G4NEJ8 GSQVDAEGNPFWEISDKRRVGISQFKKMDFINIREYYEAGGEMKPGKKGIGLTVDQYTAFLKAIPAINAELRSRGHDIT 4bhm D 2.70 BS01 NUC G 1 S60 F62 M65 F67 N69 R71 Y74 P82 G83 K84 S22 F24 M27 F29 N31 R33 Y36 P41 G42 K43 G4NEJ8 SQVDAEGNPFWEISDKRRVGISQFKKMDFINIREYYEAMKPGKKGIGLTVDQYTAFLKAIPAINAELRSRGHDIT 4bhm D 2.70 BS02 NUC I 1 R55 K85 R17 K44 G4NEJ8 SQVDAEGNPFWEISDKRRVGISQFKKMDFINIREYYEAMKPGKKGIGLTVDQYTAFLKAIPAINAELRSRGHDIT 4biz A 2.65 BS01 ADP A 1 N360 R363 Y364 D386 P389 V391 I399 Y404 R405 T406 A409 G416 T417 G418 G420 L421 L445 N140 R143 Y144 D166 P169 V171 I179 Y184 R185 T186 A189 G194 T195 G196 G198 L199 L223 2.7.13.3 P0AE82 AGASFNQMVTALERMMTSQQRLLSDISEELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARDREGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYK 4biz E 2.65 BS01 ADP E 1 N360 Y364 D386 P389 V391 I399 Y404 R405 T406 A409 G416 T417 G418 G420 L421 L445 N138 Y142 D164 P167 V169 I177 Y182 R183 T184 A187 G190 T191 G192 G194 L195 L219 2.7.13.3 P0AE82 ASFNQMVTALERMMTSQQRLLSDISEELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARDGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYK 4biz F 2.65 BS01 ADP F 1 N360 R363 Y364 D386 G390 V391 I399 T406 T417 G418 L419 G420 L421 L445 N138 R141 Y142 D164 G168 V169 I177 T184 T186 G187 L188 G189 L190 L214 2.7.13.3 P0AE82 ASFNQMVTALERMMTSQQRLLSDISEELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYKR 4bj0 A 1.00 BS02 BGC A 1 E112 R115 H117 E111 R114 H116 3.2.1.8 Q6V8M0 LVANINGGFESTPAGVVTDLAEGVEGWDLNVGSSVTNPPVFEVLETSDAPEGNKVLAVTVNGVGNNPFNIQATALPVNVRPGVTYTYTIRARAEQDGAVVSFTVGNQSFDEYGRLHHQQITTEWQPFTFEFTVSDQETVIRAPIHFGYAANVGNTIYIDGLAIVDL 4bj0 A 1.00 BS04 BGC A 2 F110 E112 R115 F109 E111 R114 3.2.1.8 Q6V8M0 LVANINGGFESTPAGVVTDLAEGVEGWDLNVGSSVTNPPVFEVLETSDAPEGNKVLAVTVNGVGNNPFNIQATALPVNVRPGVTYTYTIRARAEQDGAVVSFTVGNQSFDEYGRLHHQQITTEWQPFTFEFTVSDQETVIRAPIHFGYAANVGNTIYIDGLAIVDL 4bj0 A 1.00 BS05 BGC A 3 F69 F110 H146 F68 F109 H145 3.2.1.8 Q6V8M0 LVANINGGFESTPAGVVTDLAEGVEGWDLNVGSSVTNPPVFEVLETSDAPEGNKVLAVTVNGVGNNPFNIQATALPVNVRPGVTYTYTIRARAEQDGAVVSFTVGNQSFDEYGRLHHQQITTEWQPFTFEFTVSDQETVIRAPIHFGYAANVGNTIYIDGLAIVDL 4bj0 A 1.00 BS06 XYS A 1 F69 R115 H117 H146 Y149 F68 R114 H116 H145 Y148 3.2.1.8 Q6V8M0 LVANINGGFESTPAGVVTDLAEGVEGWDLNVGSSVTNPPVFEVLETSDAPEGNKVLAVTVNGVGNNPFNIQATALPVNVRPGVTYTYTIRARAEQDGAVVSFTVGNQSFDEYGRLHHQQITTEWQPFTFEFTVSDQETVIRAPIHFGYAANVGNTIYIDGLAIVDL 4bj0 A 1.00 BS07 XYS A 2 F69 Q72 T74 P144 H146 F68 Q71 T73 P143 H145 3.2.1.8 Q6V8M0 LVANINGGFESTPAGVVTDLAEGVEGWDLNVGSSVTNPPVFEVLETSDAPEGNKVLAVTVNGVGNNPFNIQATALPVNVRPGVTYTYTIRARAEQDGAVVSFTVGNQSFDEYGRLHHQQITTEWQPFTFEFTVSDQETVIRAPIHFGYAANVGNTIYIDGLAIVDL 4cbk B 2.42 BS01 DPV B 1 I19 I23 K26 I19 I23 K26 P22483 24707994 MAFLGAAIAAGLAAVAGAIAVAIIVKATIEGTTRQPELRGTLQTLMFIGVPLAEAVPIIAIVISLLILF 4cbk L 2.42 BS01 DPV L 1 V15 I23 K26 V15 I23 K26 P22483 24707994 MAFLGAAIAAGLAAVAGAIAVAIIVKATIEGTTRQPELRGTLQTLMFIGVPLAEAVPIIAIVISLLILF 4cqo A 2.80 BS01 III B 1 I2330 K2331 W2338 E2350 F2353 Q2354 A2357 Q2358 M2361 I479 K480 W487 E499 F502 Q503 A506 Q507 M510 A5YKK6 YDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCM 4cqo C 2.80 BS01 III D 1 I2330 K2331 W2338 E2350 F2353 Q2354 A2357 M2361 I485 K486 W493 E505 F508 Q509 A512 M516 A5YKK6 YDDPPGLREKAEYLLREWVNLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCM 4cxq A 1.80 BS01 PLP A 1 W65 G124 S125 Y157 H158 G159 E220 D254 I256 A257 K283 W57 G116 S117 Y149 H150 G151 E212 D246 I248 A249 K275 2.6.1.62 P9WQ80 24482078 LTPEQIIAVDGAHLWHPYSSIGREVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4cxq A 1.80 BS02 KAP A 1 Y25 W64 Y157 A226 K283 R400 Y18 W56 Y149 A218 K275 R392 2.6.1.62 P9WQ80 24482078 LTPEQIIAVDGAHLWHPYSSIGREVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4cxq B 1.80 BS04 KAP B 1 Y25 W64 W65 Y157 A226 K283 R400 Y18 W55 W56 Y148 A217 K274 R391 2.6.1.62 P9WQ80 24482078 LTPEQIIAVDGAHLWHPYSSIGRESPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4cxr A 1.70 BS02 2BG A 1 Y25 W64 W65 Y157 M174 A226 Y18 W54 W55 Y147 M164 A216 2.6.1.62 P9WQ80 24482078 LTPEQIIAVDGAHLWHPYSSIGRSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4j09 A 1.90 BS01 III B 1 Q73 H122 A124 H125 T140 A142 G143 A158 H160 G176 V177 H191 Q73 H122 A124 H125 T140 A142 G143 A158 H160 G176 V177 H191 2.3.1.129 P0A722 MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR 4jhu A 1.89 BS05 CU A 5 H401 D441 H401 D441 GIGPVTDLTISDGPVSPDGFTRQAILVNNQFPSPLITGNKGDRFQLNVIDNMNNHTMLKSTSIHWHGFFQHGTNWADGPAFVNQCPISPGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPIVVYDPQDPHKDLYDVDDDSTVITLADWYHLAAKVGPAVPTADATLINGLGRSISTLNADLAVISVTKGKRYRFRLVSLSCDPNHTFSIDGHTMTVIEADSVNLKPQVVDSIQIFAAQRYSFVLNADQDIGNYWIRAMPNSGTRNFDGGVNSAILRYDGADPVEPTTTQTPSSQPLVESALTTLEGTAAPGSPTAGGVDLAINMAFGFAGGRFTINGASFTPPTVPVLLQILSGAQNAQDLLPTGSVYSLPANADIEISLPATAAAPGFPHPFHLHGHTFAVVRSAGSSTYNYANPVYRDVVSTGSPGDNVTIRFRTDNPGPWFLHCHIDFHLEAGFAVVMAEDIPDVAAVNPVPQAWSDLCPTYNALDPNDQ 4jhu A 1.89 BS06 CU A 6 D378 R439 D378 R439 GIGPVTDLTISDGPVSPDGFTRQAILVNNQFPSPLITGNKGDRFQLNVIDNMNNHTMLKSTSIHWHGFFQHGTNWADGPAFVNQCPISPGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPIVVYDPQDPHKDLYDVDDDSTVITLADWYHLAAKVGPAVPTADATLINGLGRSISTLNADLAVISVTKGKRYRFRLVSLSCDPNHTFSIDGHTMTVIEADSVNLKPQVVDSIQIFAAQRYSFVLNADQDIGNYWIRAMPNSGTRNFDGGVNSAILRYDGADPVEPTTTQTPSSQPLVESALTTLEGTAAPGSPTAGGVDLAINMAFGFAGGRFTINGASFTPPTVPVLLQILSGAQNAQDLLPTGSVYSLPANADIEISLPATAAAPGFPHPFHLHGHTFAVVRSAGSSTYNYANPVYRDVVSTGSPGDNVTIRFRTDNPGPWFLHCHIDFHLEAGFAVVMAEDIPDVAAVNPVPQAWSDLCPTYNALDPNDQ 4jhv A 1.60 BS03 CU A 3 H394 C450 H455 H394 C450 H455 GIGPVTDLTISDGPVSPDGFTRQAILVNNQFPSPLITGNKGDRFQLNVIDNMNNHTMLKSTSIHWHGFFQHGTNWADGPAFVNQCPISPGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPIVVYDPQDPHKDLYDVDDDSTVITLADWYHLAAKVGPAVPTADATLINGLGRSISTLNADLAVISVTKGKRYRFRLVSLSCDPNHTFSIDGHTMTVIEADSVNLKPQVVDSIQIFAAQRYSFVLNADQDIGNYWIRAMPNSGTRNFDGGVNSAILRYDGADPVEPTTTQTPSSQPLVESALTTLEGTAAPGSPTAGGVDLAINMAFGFAGGRFTINGASFTPPTVPVLLQILSGAQNAQDLLPTGSVYSLPANADIEISLPATAAAPGFPHPFHLHGHTFAVVRSAGSSTYNYANPVYRDVVSTGSPGDNVTIRFRTDNPGPWFLHCHIDFHLEAGFAVVMAEDIPDVAAVNPVPQAWSDLCPTYNALDPNDQ 4jmg A 1.40 BS01 III B 1 R47 R66 S68 S70 S76 Q86 H87 F88 K89 L100 W101 Y142 R144 Y184 G186 K190 Y191 Y192 Q194 R41 R60 S62 S64 S70 Q80 H81 F82 K83 L94 W95 Y136 R138 Y178 G180 K184 Y185 Y186 Q188 VKFNSLNELVDYHRSTSVSRNQQIFLRDIGGHPWYKGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVGGSGGSVSSVPTKLEVVAATPTSLLISWDAWSGSDWPVSYYRITYGETGGNSPVQEFTVPGSSYTATISGLSPGVDYTITVYAGYDGKYYYQSPISINYRT 4jmh A 2.41 BS01 III B 1 S21 R22 N23 R47 R66 S68 E69 S70 S76 F81 Q86 H87 F88 K89 L91 L100 W101 V102 Y137 Y138 V139 S140 H187 R188 S21 R22 N23 R45 R64 S66 E67 S68 S74 F79 Q84 H85 F86 K87 L89 L98 W99 V100 Y135 Y136 V137 S138 H185 R186 GSVKFNSLDELVDYHRSTSVSRNQQIFLRDIGGGGHPWYKGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVGGSGGSVSSVPTKLEVVAATPTSLLISWDAIWYPYYVSYYRITYGETGGNSPVQEFTVPGYSSTATISGLSPGVDYTITIYAKYHRAKYYSSPISINYRT 4js9 A 2.78 BS01 MH0 A 1 W188 A191 R193 C194 I195 Q199 M349 F363 N364 G365 W366 E371 M428 W457 Y483 Y485 W101 A104 R106 C107 I108 Q112 M260 F274 N275 G276 W277 E282 M339 W368 Y394 Y396 1.14.13.39 P29477 QYVRIKNWGSGEILHDTLHHKATSSIMNPKSLTRGPRDKPTPLEELLPHAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARNCSTAQEMFQHICRHILYATNNGNIRSAITVFPQRSDGKHDFRLWNSQLIRYAGYQMPTIRGDAATLEFTQLCIDLGWKPRYGRFDVLPLVLQADGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHI 4js9 B 2.78 BS01 MH0 B 1 W188 C194 G196 Q199 M349 F363 N364 G365 W366 E371 W457 Y483 Y485 W101 C107 G109 Q112 M259 F273 N274 G275 W276 E281 W367 Y393 Y395 1.14.13.39 P29477 YVRIKNWGSGEILHDTLHHKATSGSIMNPKSLTRGPRDKPTPLEELLPHAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARNCSTAQEMFQHICRHILYATNNGNIRSAITVFPQRSDGKHDFRLWNSQLIRYAGYQMTIRGDAATLEFTQLCIDLGWKPRYGRFDVLPLVLQADGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKT 4jy0 A 2.20 BS01 1O9 A 1 P197 R200 C366 S367 S368 L384 R386 R394 S407 G410 M414 Y415 Q446 Y448 G449 P193 R196 C362 S363 S364 L380 R382 R390 S403 G406 M410 Y411 Q442 Y444 G445 3.4.22.-,3.4.21.98,3.6.1.15,3.6.4.13,2.7.7.48 O92972 SMSYTWTGALITPCAAEESKLPINPLSNSLLRHHNMVYATTSRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSIEEACKLTPPHSAKSKFGYGAKDVRNLSSRAVNHIRSVWEDLLEDTETPIDTTIMAKSEVFCVQPRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQRVEFLVNTWKSKKCPMGFSYDTRCFDSTVTESDIRVEESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKATAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAAALRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPINSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFTLHSYSPGEINRVASCLRKLGVPPLRTWRHRARSVRAKLLSQGGRAATCGRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYHS 4jy0 B 2.20 BS01 1O9 B 1 R200 C366 S368 L384 R386 S407 G410 N411 M414 Y415 Q446 I447 Y448 G449 R195 C361 S363 L379 R381 S402 G405 N406 M409 Y410 Q441 I442 Y443 G444 3.4.22.-,3.4.21.98,3.6.1.15,3.6.4.13,2.7.7.48 O92972 SMSYTWTGALITPCAAEESKLPINPLSNSLLRHHNMVYATTSRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSIEEACKLTPPHSAKSKFGYGAKDVRNLSSRAVNHIRSVWEDLLEDTETPIDTTIMAKSEVFCVGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQRVEFLVNTWKSKKCPMGFSYDTRCFDSTVTESDIRVEESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKATAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAAALRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPINSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFTLHSYSPGEINRVASCLRKLGVPPLRTWRHRARSVRAKLLSQGGRAATCGRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYHS 4jy1 A 2.60 BS01 NN3 A 1 L419 R422 M423 H475 S476 Y477 I482 W528 L415 R418 M419 H471 S472 Y473 I478 W524 3.4.22.-,3.4.21.98,3.6.1.15,3.6.4.13,2.7.7.48 O92972 SMSYTWTGALITPCAAEESKLPINPLSNSLLRHHNMVYATTSRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSIEEACKLTPPHSAKSKFGYGAKDVRNLSSRAVNHIRSVWEDLLEDTETPIDTTIMAKSEVFCVQPRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQRVEFLVNTWKSKKCPMGFSYDTRCFDSTVTESDIRVEESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKATAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAAALRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPINSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFTLHSYSPGEINRVASCLRKLGVPPLRTWRHRARSVRAKLLSQGGRAATCGRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYHS 4jyq B 1.80 BS01 HEM B 1 E31 Y34 F35 H55 K58 V59 L83 M86 Q88 H89 L92 N96 F97 L100 L127 E31 Y34 F35 H55 K58 V59 L83 M86 Q88 H89 L92 N96 F97 L100 L127 Q9NAV8 GFKQDIATIRGDLRTYAQDIFLAFLNKYPDERRYFKNYVGKSDQELKSMAKFGDHTEKVFNLMMEVADRATDCVPLASDANTLVQMKQHSSLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK 4k1r A 1.63 BS01 ZN A 1 H304 H332 H58 H86 3.4.19.- Q9P371 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRVK 4k1r A 1.63 BS02 ZN A 2 H341 H343 D354 H95 H97 D108 3.4.19.- Q9P371 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRVK 4k1r A 1.63 BS03 ZN A 3 H356 C397 H404 H406 H110 C151 H158 H160 3.4.19.- Q9P371 TFKIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQNAFFITHLVIPLQEATSDTCGTTDEASLFEFQDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCRKPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLRVK 4k7n B 2.30 BS01 MCT B 1 T44 P45 G46 C47 F120 R127 T44 P45 G46 C47 F120 R127 1.11.1.15 P30044 APIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL 4k7o A 1.98 BS01 EKZ A 1 P40 T44 P45 G46 C47 L116 I119 F120 R127 T147 P41 T45 P46 G47 C48 L117 I120 F121 R128 T148 1.11.1.15 P30044 SAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL 4k7o C 1.98 BS01 EKZ C 1 T44 P45 G46 C47 L116 R127 T43 P44 G45 C46 L115 R126 1.11.1.15 P30044 PIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL 4k8y A 1.00 BS01 III B 1 F41 C42 H57 L99 M147 L167 D187 S188 C189 N190 G191 D192 S193 V207 S208 F209 G210 K211 A212 F25 C26 H41 L83 M131 L151 D171 S172 C173 N174 G175 D176 S177 V191 S192 F193 G194 K195 A196 3.4.21.- Q9Y5K2 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 4k9q A 1.60 BS01 MG A 1 D429 N456 E458 D429 N456 E458 4.1.1.7 A4SXU0 MRTVKEITFDLLRKLQVTTVVGNPGSTEETFLKDFPSDFNYVLALQEASVVAIADGLSQSLRKPVIVNIHTGAGLGNAMGCLLTAYQNKTPLIITAGQQTREMLLNEPLLTNIEAINMPKPWVKWSYEPARPEDVPGAFMRAYATAMQQPQGPVFLSLPLDDWEKLIPEVDVARTVSTRQGPDPDKVKEFAQRITASKNPLLIYGSDIARSQAWSDGIAFAERLNAPVWAAPFAERTPFPEDHPLFQGALTSGIGSLEKQIQGHDLIVVIGAPVFRYYPWIAGQFIPEGSTLLQVSDDPNMTSKAVVGDSLVSDSKLFLIEALKLIDQREKNNTPQRSPMTKEDRTAMPLRPHAVLEVLKENSPKEIVLVEECPSIVPLMQDVFRINQPDTFYTFASGGLGWDLPAAVGLALGEEVSGRNRPVVTLMGDGSFQYSVQGIYTGVQQKTHVIYVVFQNEEYGILKQFAELEQTPNVPGLDLPGLDIVAQGKAYGAKSLKVETLDELKTAYLEALSFKGTSVIVVPITKELKPL 4k9q A 1.60 BS02 TPP A 1 C373 P374 S375 G398 L400 G428 D429 G430 S431 Y434 N456 E458 Y459 G460 I461 L462 C373 P374 S375 G398 L400 G428 D429 G430 S431 Y434 N456 E458 Y459 G460 I461 L462 4.1.1.7 A4SXU0 MRTVKEITFDLLRKLQVTTVVGNPGSTEETFLKDFPSDFNYVLALQEASVVAIADGLSQSLRKPVIVNIHTGAGLGNAMGCLLTAYQNKTPLIITAGQQTREMLLNEPLLTNIEAINMPKPWVKWSYEPARPEDVPGAFMRAYATAMQQPQGPVFLSLPLDDWEKLIPEVDVARTVSTRQGPDPDKVKEFAQRITASKNPLLIYGSDIARSQAWSDGIAFAERLNAPVWAAPFAERTPFPEDHPLFQGALTSGIGSLEKQIQGHDLIVVIGAPVFRYYPWIAGQFIPEGSTLLQVSDDPNMTSKAVVGDSLVSDSKLFLIEALKLIDQREKNNTPQRSPMTKEDRTAMPLRPHAVLEVLKENSPKEIVLVEECPSIVPLMQDVFRINQPDTFYTFASGGLGWDLPAAVGLALGEEVSGRNRPVVTLMGDGSFQYSVQGIYTGVQQKTHVIYVVFQNEEYGILKQFAELEQTPNVPGLDLPGLDIVAQGKAYGAKSLKVETLDELKTAYLEALSFKGTSVIVVPITKELKPL 4kp1 A 1.80 BS01 KP1 A 1 F300 S303 C304 L372 S384 F390 F299 S302 C303 L371 S383 F389 4.2.1.33,4.2.1.35 P81291 24699638 GMTIVEKILAKASGKKEVSPGDIVMANIDVAMVHDITGPLTVNTLKEYGIEKVWNPEKIVILFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIREGVCHQVLPEKGHVAPGEVVVGADSHTCTHGAFGAFATGIGSTDMAHVFATGKLWFKVPETIYFNITGDLQPYVTSKDVILSIIGEVGVDGATYKACQFGGETVKKMSIASRMTMTNMAIEMGGKTGIIEPDEKTIQYVKEAMKKHGTERPFEVIKGDEDAEFAEVYEIEADKIEPVFACPHNVDNVKQAREVAGKPIDQVFIGSCTNGRLEDLRMAIKIIEKHGGIADDVRVVVTPASREEYLKALKEGIIEKFLKYGCVVTNPSCSACMGSLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACAVKGELVDPRDL 4kp1 A 1.80 BS02 MG A 1 H103 H124 N215 C304 T305 R388 H102 H123 N214 C303 T304 R387 4.2.1.33,4.2.1.35 P81291 24699638 GMTIVEKILAKASGKKEVSPGDIVMANIDVAMVHDITGPLTVNTLKEYGIEKVWNPEKIVILFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIREGVCHQVLPEKGHVAPGEVVVGADSHTCTHGAFGAFATGIGSTDMAHVFATGKLWFKVPETIYFNITGDLQPYVTSKDVILSIIGEVGVDGATYKACQFGGETVKKMSIASRMTMTNMAIEMGGKTGIIEPDEKTIQYVKEAMKKHGTERPFEVIKGDEDAEFAEVYEIEADKIEPVFACPHNVDNVKQAREVAGKPIDQVFIGSCTNGRLEDLRMAIKIIEKHGGIADDVRVVVTPASREEYLKALKEGIIEKFLKYGCVVTNPSCSACMGSLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACAVKGELVDPRDL 4kr6 A 2.85 BS01 NUC D 1 S12 E13 L16 K17 K19 N20 R21 K22 R42 K104 V105 Q106 A107 K108 Y119 N122 S123 G126 A127 L130 V138 V140 R141 S12 E13 L16 K17 K19 N20 R21 K22 R42 K104 V105 Q106 A107 K108 Y119 N122 S123 G126 A127 L130 V138 V140 R141 2.8.1.4 Q9X220 24705700 MEELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr6 B 2.85 BS01 NUC C 1 R10 Y11 S12 E13 E25 E26 R42 W44 G45 R46 Q68 N69 K104 V105 Q106 K108 K109 V118 Y119 N122 S123 G126 A127 V138 V140 R141 R152 R162 R10 Y11 S12 E13 E25 E26 R42 W44 G45 R46 Q68 N69 K104 V105 Q106 K108 K109 V118 Y119 N122 S123 G126 A127 V138 V140 R141 R152 R162 2.8.1.4 Q9X220 24705700 MEELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr6 B 2.85 BS02 NUC D 1 K257 Y333 P339 Q341 N351 P352 A353 T354 K257 Y333 P339 Q341 N351 P352 A353 T354 2.8.1.4 Q9X220 24705700 MEELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr7 A 3.42 BS01 NUC M 1 I14 G15 L16 K17 G18 K19 R21 K22 R42 K104 V105 K108 A110 Y111 V118 Y119 N122 S123 G126 A127 L130 V138 V140 R141 R152 I12 G13 L14 K15 G16 K17 R19 K20 R40 K102 V103 K106 A108 Y109 V116 Y117 N120 S121 G124 A125 L128 V136 V138 R139 R150 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr7 A 3.42 BS02 ATP A 1 L180 L181 S182 G184 I185 D186 S187 V204 T205 F206 R264 M267 T285 G286 E287 Q295 L178 L179 S180 G182 I183 D184 S185 V202 T203 F204 R262 M265 T283 G284 E285 Q293 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr7 B 3.42 BS01 NUC M 1 Y340 N351 Y338 N349 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr7 B 3.42 BS02 NUC X 1 R21 K104 V105 Q106 A107 K108 Y119 S123 G126 A127 L130 V138 V140 R141 R19 K102 V103 Q104 A105 K106 Y117 S121 G124 A125 L128 V136 V138 R139 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr7 B 3.42 BS03 ATP B 1 L180 L181 S182 D186 S187 V204 T205 F206 R264 M267 G286 E287 N288 K320 L178 L179 S180 D184 S185 V202 T203 F204 R262 M265 G284 E285 N286 K318 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr9 A 3.50 BS01 NUC M 1 G15 K17 G18 R21 R42 K104 V105 K108 A110 V118 Y119 N122 S123 G126 A127 L130 V138 V140 R152 G13 K15 G16 R19 R40 K102 V103 K106 A108 V116 Y117 N120 S121 G124 A125 L128 V136 V138 R150 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr9 B 3.50 BS01 NUC M 1 K338 N351 K336 N349 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4kr9 B 3.50 BS02 NUC X 1 K19 R21 K104 V105 Q106 A107 K108 Y119 N122 S123 G126 A127 L130 V138 V140 R141 K17 R19 K102 V103 Q104 A105 K106 Y117 N120 S121 G124 A125 L128 V136 V138 R139 2.8.1.4 Q9X220 24705700 ELRVYIVRYSEIGLKGKNRKDFEEALRRNIERVTGMKVKRQWGRFLIPIDENVTLDDKLKKIFGIQNFSKGFLVSHDFEEVKKYSLIAVKEKLEKGNYRTFKVQAKKAYKEYKKGVYEINSELGALILKNFKELSVDVRNPDFVLGVEVRPEGVLIFTDRVECYGGLPVGTGGKAVLLLSGGIDSPVAGWYALKRGVLIESVTFVSPPFTSEGAVEKVRDILRVLREFSGGHPLRLHIVNLTKLQLEVKKRVPDKYSLIMYRRSMFRIAEKIAEETGAVAFYTGENIGQVASQTLENLWSIESVTTRPVIRPLSGFDKTEIVEKAKEIGTYEISIKPYQDSCVFFAPKNPATRSHPSILEKLEQQVPDLPVLEEEAFTSRKVEVIE 4m37 A 1.70 BS01 SAH A 1 M75 R81 E101 I102 G103 A104 G105 L109 V124 E125 G126 L130 M152 M153 S154 I173 Y186 M38 R44 E64 I65 G66 A67 G68 L72 V87 E88 G89 L93 M115 M116 S117 I136 Y149 2.1.1.- Q582G4 24726341 RPPDAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLC 4m38 A 2.20 BS01 III E 1 D70 F71 M75 E172 F174 G175 T176 G180 E181 F246 K248 H249 Q329 W330 D30 F31 M35 E132 F134 G135 T136 G140 E141 F206 K208 H209 Q289 W290 2.1.1.- Q582G4 24726341 DAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLC 4m38 A 2.20 BS02 SAH A 1 H72 M75 R81 E101 I102 G103 A104 S106 L109 V124 E125 G126 L130 M152 M153 S154 Y186 H32 M35 R41 E61 I62 G63 A64 S66 L69 V84 E85 G86 L90 M112 M113 S114 Y146 2.1.1.- Q582G4 24726341 DAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLC 4m38 B 2.20 BS01 III F 1 M75 E172 F174 G175 T176 M177 G180 E181 F246 Q329 W330 M35 E132 F134 G135 T136 M137 G140 E141 F206 Q289 W290 2.1.1.- Q582G4 24726341 DAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLC 4m38 B 2.20 BS02 SAH B 1 H72 M75 R81 E101 I102 G103 A104 G105 L109 V124 E125 G126 L130 M152 M153 S154 E172 I173 Y186 H32 M35 R41 E61 I62 G63 A64 G65 L69 V84 E85 G86 L90 M112 M113 S114 E132 I133 Y146 2.1.1.- Q582G4 24726341 DAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLC 4mi1 A 1.40 BS01 DSZ A 1 I84 G85 G86 Y111 A112 D113 P137 F177 W180 N210 N212 T213 K239 E269 A303 I83 G84 G85 Y110 A111 D112 P136 F176 W179 N209 N211 T212 K238 E268 A302 Q81RT8 PLPKSLKYGDTIGIYSPSSPVTYTSPKRFERAKSYLLQKGFHILEGSLTGRYDYYRSGSIQERAKELNALIRNPNVSCIMSTIGGMNSNSLLPYIDYDAFQNNPKIMIGYADATALLLGIYAKTGIPTFYGPALVPSFGEFEPFVDDTYKYFLETLLHDQALPYNIKQPLFWSDEFINWEEKTKEKELRPNNWISVTNGQATGRVIGGNLNTIQGIWGSPYMPCIQEGDILFIEDSSKDAATIERSFSFLKINGVFDKVSGIILGKHEQFDDCGTNRKPYEILLEVLQNQRIPLLADFDCCATHPMITMPIGVQVKMDATNKTIHILEKWKI 4mrt C 2.00 BS01 COA A 1 H44 A45 F69 H37 A38 F62 O30409 24704508 YVAPTNAVESKLAEIWERVLGVSGIGILDNFFQIGGHALKAMAVAAQVHREYQVELPLKVLFAQPTIKALAQYVATR 4mrt A 2.00 BS01 MG A 1 D107 E151 D107 E151 2.7.8.- P39135 24704508 MKIYGIYMDRPLSQEENERFMTFISPEKREKCRRFYHKEDAHRTLLGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDSQPIGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSLPLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEELLR 4mrt A 2.00 BS02 COA A 1 K31 T44 Y73 G74 K75 P76 N87 I88 S89 H90 D107 E151 K155 G158 G160 L161 S162 K31 T44 Y73 G74 K75 P76 N87 I88 S89 H90 D107 E151 K155 G158 G160 L161 S162 2.7.8.- P39135 24704508 MKIYGIYMDRPLSQEENERFMTFISPEKREKCRRFYHKEDAHRTLLGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDSQPIGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSLPLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEELLR 4mvj A 2.85 BS01 PO4 A 1 K257 A295 K296 K257 A295 K296 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj A 2.85 BS02 POP A 1 G11 R12 I13 A181 G11 R12 I13 A181 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj B 2.85 BS01 PO4 B 1 Y253 K257 A295 K296 Y254 K258 A296 K297 1.2.1.12 C9QTS9 AMTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj B 2.85 BS02 POP B 1 G11 R12 I13 G12 R13 I14 1.2.1.12 C9QTS9 AMTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj C 2.85 BS01 NAD C 1 N8 F10 G11 R12 I13 D34 R78 A96 T97 G98 L99 T120 C150 T180 A181 N314 Y318 N8 F10 G11 R12 I13 D34 R78 A96 T97 G98 L99 T120 C150 T180 A181 N314 Y318 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj D 2.85 BS01 NAD D 1 N8 G11 R12 I13 D34 A96 T97 G98 L99 T120 C150 A181 N314 N8 G11 R12 I13 D34 A96 T97 G98 L99 T120 C150 A181 N314 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj D 2.85 BS02 PO4 D 1 D39 Y43 K46 Y47 D39 Y43 K46 Y47 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj E 2.85 BS01 NAD E 1 N8 G9 F10 G11 R12 I13 D34 A96 T97 G98 L99 T120 C150 A181 N314 N8 G9 F10 G11 R12 I13 D34 A96 T97 G98 L99 T120 C150 A181 N314 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj I 2.85 BS01 NAD I 1 N8 F10 G11 R12 I13 D34 T97 G98 L99 T120 C150 A181 N314 Y318 N7 F9 G10 R11 I12 D33 T96 G97 L98 T119 C149 A180 N313 Y317 1.2.1.12 C9QTS9 TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj L 2.85 BS01 PO4 L 1 F166 G167 E248 K249 F166 G167 E248 K249 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj O 2.85 BS01 NAD O 1 N8 F10 G11 R12 I13 D34 A96 T97 L99 T120 C150 A181 N314 Y318 N8 F10 G11 R12 I13 D34 A96 T97 L99 T120 C150 A181 N314 Y318 1.2.1.12 C9QTS9 MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mvj P 2.85 BS01 NAD P 1 G9 G11 R12 I13 D34 A96 T97 G98 L99 T120 C150 A181 N314 E315 Y318 G8 G10 R11 I12 D33 A95 T96 G97 L98 T119 C149 A180 N313 E314 Y317 1.2.1.12 C9QTS9 TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK 4mxd A 1.45 BS01 PGE A 1 H28 L167 R236 H31 L170 R239 4.2.99.20 P37355 SGSMILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF 4myd A 1.37 BS01 164 A 1 G22 F23 Y85 S86 L87 R90 R124 W147 Y148 F153 G22 F23 Y85 S86 L87 R90 R124 W147 Y148 F153 4.2.99.20 P37355 MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF 4myd B 1.37 BS01 164 B 1 G22 F23 Y85 S86 L87 R90 W147 Y148 F153 G22 F23 Y85 S86 L87 R90 W147 Y148 F153 4.2.99.20 P37355 MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF 4mys B 1.42 BS02 PYR B 1 R124 S127 D128 W131 W147 Q150 R124 S127 D128 W131 W147 Q150 4.2.99.20 P37355 MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWVQRFLTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF 4n5v A 1.90 BS01 PRP A 1 G107 G109 G110 N117 S119 T120 K135 N138 A140 A141 S142 S143 G146 G147 E252 G85 G87 G88 N95 S97 T98 K113 N116 A118 A119 S120 S121 G124 G125 E230 2.4.2.18 P9WFX5 24712732 SVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4n5v A 1.90 BS04 FA0 A 1 V106 G107 T108 H136 G137 N138 A179 R193 G206 P207 V84 G85 T86 H114 G115 N116 A157 R171 G184 P185 2.4.2.18 P9WFX5 24712732 SVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4n7s A 2.10 BS01 ZN A 1 E258 D262 Q280 E257 D261 Q279 Q9HYC5 24724564 TATSDLIESLISYSWDDWQVTRQEARRVIAAIRNDNVPDATIAALDKSGSLIKLFQRVGPPELARSLIASIAGRTTMQRYQARNALIRSLINNPLGTQTDNWIYFPTITFFDICADLADAAGRLGFAAAGATGVASQAIQGPFSGVGATGVNPTDLPSIAFGDQLKLLNKDPATVTKYSNPLGDLGAYLSQLSPQDKLNQAQTLVGQPISTLFPDAYPGNPPSRAKVMSAAARKYDLTPQLIGAIILAEQRDQTRDEDAKDYQAAVSIKSANTSIGLGQVVVSTAIKYELFTDLLGQPVRRGLSRKAVATLLASDEFNIFATARYIRYVANLASQQDLRKLPKTRGAFPSIDLRAYAGNPRNWPRDNVRALASEYTSRPWDDNLSPGWPMFVDDAYATFLD 4n7u A 1.46 BS01 2JA A 1 R412 L414 R418 R469 R116 L118 R122 R173 O00481 24703779 GAYNEWKKALFKPADVILDPKTADPILLVSEDQRSVERAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICP 4n88 A 2.80 BS01 CA A 1 D18 Q20 E25 D17 Q19 E24 Q9HYC5 24724564 TATSDLIESLISYSWDDWQVTRQEARRVIAAIRNDNVPDATIAALDKSGSLIKLFQRVGPPELARSLIASIAGRTTMQRYQARNALIRSLINNPLGTQTDNWIYFPTITFFDICADLADAAGRLGFAAAGATGVASQAIQGPFSGVGATGVNPTDLPSIAFGDQLKLLNKDPATVTKYSNPLGDLGAYLSQLSPQDKLNQAQTLVGQPISTLFPDAYPGNPPSRAKVMSAAARKYDLTPQLIGAIILAEQRDQTRDEDAKDYQAAVSIKSANTSIGLGQVVVSTAIKYELFTDLLGQPVRRGLSRKAVATLLASDEFNIFATARYIRYVANLASQQDLRKLPKTRGAFPSIDLRAYAGNPRNWPRDNVRALASEYTSRPWDDNLSPGWPMFVDDAYATFLD 4n88 C 2.80 BS01 CA C 1 L11 D18 Q20 V21 E25 L10 D17 Q19 V20 E24 Q9HYC5 24724564 TATSDLIESLISYSWDDWQVTRQEARRVIAAIRNDNVPDATIAALDKSGSLIKLFQRVGPPELARSLIASIAGRTTMQRYQARNALIRSLINNPLGTQTDNWIYFPTITFFDICADLADAAGRLGFAAAGATGVASQAIQGPFSGVGATGVNPTDLPSIAFGDQLKLLNKDPATVTKYSNPLGDLGAYLSQLSPQDKLNQAQTLVGQPISTLFPDAYPGNPPSRAKVMSAAARKYDLTPQLIGAIILAEQRDQTRDEDAKDYQAAVSIKSANTSIGLGQVVVSTAIKYELFTDLLGQPVRRGLSRKAVATLLASDEFNIFATARYIRYVANLASQQDLRKLPKTRGAFPSIDLRAYAGNPRNWPRDNVRALASEYTSRPWDDNLSPGWPMFVDDAYATFLD 4n8q B 2.08 BS01 FA0 B 1 N138 S143 A179 P180 H183 Y186 R187 A190 R194 N111 S116 A152 P153 H156 Y159 R160 A163 R167 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQILA 4n93 A 2.03 BS03 6M1 A 1 V106 G107 T108 H136 N138 A179 R193 G206 P207 V83 G84 T85 H113 N115 A156 R170 G183 P184 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4nb5 A 1.64 BS01 2JT B 1 F79 E108 R109 R111 A112 E115 F63 E92 R93 R95 A96 E99 I6Y8F7 DIMEFVEQMGGYFESRSLTRLAGRLLGWLLVCDPERQSSEELATALAASSGGISTNARMLIQFGFIERLAVAGDRRTYFRLRPNAFAAGERERIRAMAELQDLADVGLRALGDAPPQRSRRLREMRDLLAYMENVVSDALGRYSQ 4nb5 B 1.64 BS01 2JT B 1 R32 F79 F81 G105 E106 E108 R109 R18 F65 F67 G91 E92 E94 R95 I6Y8F7 EPDIMEFVEQMGGYFESRSLTRLAGRLLGWLLVCDPERQSSEELATALAASSGGISTNARMLIQFGFIERLAVAGDRRTYFRLRPNAFAAGERERIRAMAELQDLADVGLRALGDAPPQRSRRLREMRDLLAYMENVVSDALGRYSQRT 4nb5 C 1.64 BS01 2JT C 1 R32 L34 F81 F102 G105 E106 R17 L19 F66 F87 G90 E91 I6Y8F7 PDIMEFVEQMGGYFESRSLTRLAGRLLGWLLVCDPERQSSEELATALAASSGGISTNARMLIQFGFIERLAVAGDRRTYFRLRPNAFAAGERERIRAMAELQDLADVGLRALGDAPPQRSRRLREMRDLLAYMENVVSDALGRYSQR 4nb5 D 1.64 BS01 2JT C 1 E108 R109 R111 A112 E115 L116 E93 R94 R96 A97 E100 L101 I6Y8F7 PDIMEFVEQMGGYFESRSLTRLAGRLLGWLLVCDPERQSSEELATALAASSGGISTNARMLIQFGFIERLAVAGDRRTYFRLRPNAFAAGERERIRAMAELQDLADVGLRALGDAPPQRSRRLREMRDLLAYMENVVSDALGRYSQ 4nes A 1.42 BS01 UD1 A 1 P11 Q37 H38 Y39 S40 S64 H67 T96 N97 E129 H207 R208 H241 P242 R243 K246 P11 Q37 H38 Y39 S40 S64 H67 T96 N97 E129 H205 R206 H239 P240 R241 K244 5.1.3.14 Q58899 24470206 MKLSIILGTRPEIIKLSPIIRALEKTNIDWHIIHTNQHYSENMDKIFFEELNLPNPKYNLNIGSGTHGEQTGKMLIEIEKVLLKEKPDVVVVQGDTNTVLAGALVASKLKIDVAHVEAGLRSFDRNMPEEINRVLTDHISSYLFAPTEIAKNNLLREGIEENKIFVVGNTIVDATLQNLKIAEKNENVRAFFNSVVDDYFLLTLHRAENVDNKERLKNIVEGIFEIIEIYDKAIIFSIHPRTKKRLKEFNLFDKLKSNKKIKIIEPVGYLEFLMLEKNAELILTDSGGVQEEACILKVPCITLRDNTERPETVEVGANILVGDNKEKLIKAVEIMLNKKRNWKNPFGNGKSGERIVRILTYG 4nes A 1.42 BS02 UDP A 1 R10 P11 I14 F47 H207 R208 S239 P268 V269 Y271 F274 S288 G289 G290 E294 R10 P11 I14 F47 H205 R206 S237 P266 V267 Y269 F272 S286 G287 G288 E292 5.1.3.14 Q58899 24470206 MKLSIILGTRPEIIKLSPIIRALEKTNIDWHIIHTNQHYSENMDKIFFEELNLPNPKYNLNIGSGTHGEQTGKMLIEIEKVLLKEKPDVVVVQGDTNTVLAGALVASKLKIDVAHVEAGLRSFDRNMPEEINRVLTDHISSYLFAPTEIAKNNLLREGIEENKIFVVGNTIVDATLQNLKIAEKNENVRAFFNSVVDDYFLLTLHRAENVDNKERLKNIVEGIFEIIEIYDKAIIFSIHPRTKKRLKEFNLFDKLKSNKKIKIIEPVGYLEFLMLEKNAELILTDSGGVQEEACILKVPCITLRDNTERPETVEVGANILVGDNKEKLIKAVEIMLNKKRNWKNPFGNGKSGERIVRILTYG 4nsv A 0.90 BS01 2OY A 1 H57 Y169 T189 E190 P191 G192 S194 H210 G211 G212 S214 D225 H57 Y169 T189 E190 P191 G192 S194 H210 G211 G212 S214 D225 3.4.21.50 Q7M135 GVSGSCNIDVVCPEGNGHRDVIRSVAAYSRQGTMWCTGSLVNNSANDKKMYFLTANHCGMTTAAIASSMVVYWNYQNSTCRAPGSSSSGANGDGSLAQSQTGAVVRATNAASDFTLLELNTAANPAYNLFWAGWDRRDQNFAGATAIHHPNVAEKRISHSTVATEISGYNGATGTSHLHVFWQASGGVTEPGSSGSPIYSPEKRVLGQLHGGPSSCSATGADRSDYYGRVFTSWTGGGTSATRLSDWLDAAGTGAQFIDGLDST 4nsv A 0.90 BS02 2OY B 1 A110 Y169 H210 A110 Y169 H210 3.4.21.50 Q7M135 GVSGSCNIDVVCPEGNGHRDVIRSVAAYSRQGTMWCTGSLVNNSANDKKMYFLTANHCGMTTAAIASSMVVYWNYQNSTCRAPGSSSSGANGDGSLAQSQTGAVVRATNAASDFTLLELNTAANPAYNLFWAGWDRRDQNFAGATAIHHPNVAEKRISHSTVATEISGYNGATGTSHLHVFWQASGGVTEPGSSGSPIYSPEKRVLGQLHGGPSSCSATGADRSDYYGRVFTSWTGGGTSATRLSDWLDAAGTGAQFIDGLDST 4nw3 A 2.82 BS01 NUC B 1 S1152 R1154 K1176 K1186 Q1187 C1188 K1193 S3 R5 K27 K37 Q38 C39 K44 Q03164 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM 4nw3 A 2.82 BS02 NUC C 1 I1184 K1185 K1186 Q1187 M1200 I35 K36 K37 Q38 M51 Q03164 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM 4nw3 A 2.82 BS03 ZN A 1 C1167 C1170 C1173 C1189 C18 C21 C24 C40 Q03164 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWM 4o1w A 2.00 BS01 HEM A 1 M13 C14 C17 H18 Y29 P30 L32 Y39 L40 Q43 L44 F47 R52 D54 T56 M57 M60 L72 M12 C13 C16 H17 Y28 P29 L31 Y38 L39 Q42 L43 F46 R51 D53 T55 M56 M59 L71 Q48A34 GDAAAGKAKSVMCAACHGAAGVSAVPTYPNLAGQKEAYLTKQLNDFKSGKRNDPTMKGMVMALSPADMENLAAYYANMK 4o1w A 2.00 BS02 HEM D 1 Y39 K42 Q43 Y38 K41 Q42 Q48A34 GDAAAGKAKSVMCAACHGAAGVSAVPTYPNLAGQKEAYLTKQLNDFKSGKRNDPTMKGMVMALSPADMENLAAYYANMK 4o45 A 1.87 BS01 III B 1 A47 V48 S49 A65 S91 D107 F133 Y260 C261 F263 I305 L321 A18 V19 S20 A36 S62 D78 F104 Y231 C232 F234 I276 L292 P61964 PVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4obo A 2.10 BS01 2QV A 1 V31 Y36 V39 A52 K54 M105 E106 F107 C108 L160 V170 D171 V16 Y21 V24 A37 K39 M81 E82 F83 C84 L136 V146 D147 2.7.11.1 O95819 24673130 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEIKLEINMLKKYSHHRNIATYYGAFIKKSDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4obp A 2.27 BS01 MG A 1 S77 H79 I82 T84 S65 H67 I70 T72 2.7.11.1 O95819 24673130 IDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSANTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4oim A 1.85 BS02 JUS A 1 G96 F97 M103 F149 P156 Y158 M161 K165 A198 M199 I202 L218 G94 F95 M101 F147 P154 Y156 M159 K163 A196 M197 I200 L216 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS03 ACT A 1 F41 Q66 F97 I122 F39 Q64 F95 I120 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS04 ACT A 2 F97 M98 A201 F95 M96 A199 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS05 ACT A 3 G208 G212 A213 G206 G210 A211 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS06 ACT A 4 S19 H24 I194 K233 A235 S17 H22 I192 K231 A233 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS07 ACT A 5 N86 K87 N139 N84 K85 N137 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS08 ACT A 6 L61 E62 R77 L59 E60 R75 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4oim A 1.85 BS09 ACT A 7 P140 K181 Y182 G183 P138 K179 Y180 G181 1.3.1.9 P9WGR0 24616444 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4op4 A 1.65 BS02 ZN A 2 H68 D101 E164 H67 D100 E161 3.5.1.18 Q9KQ52 TDSPVLALAKELISRQSVTPADAGCQDLMIERLKALGFEIESMVFEDTTNFWARRGTQSPLFVFAGHTDVVPAGPLSQWHTPPFEPTVIDGFLHGRGAADMKGSLACMIVAVERFIAEHPDHQGSIGFLITSDEEGPNGTVRVVETLMARNELIDMCIVGEPSSTLAVGDVVKNGRRGGGFLTDTGELLAAVVAAVEEVNHQAPALLTTGGTSDGRFIAQMGAQVVELGPVNATIHKVNECVRIADLEKLTDMYQKTLNHLLG 4oq3 A 2.30 BS01 2V8 A 1 L54 G58 I61 M62 Y67 Q72 F91 V93 K94 H96 I99 L37 G41 I44 M45 Y50 Q55 F74 V76 K77 H79 I82 6.3.2.- Q00987 24704029 QIPASEQETLVRPKPELLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVV 4oq3 B 2.30 BS01 2V8 B 1 L54 L57 G58 I61 M62 Y67 Q72 F91 V93 K94 H96 I99 Y100 L37 L40 G41 I44 M45 Y50 Q55 F74 V76 K77 H79 I82 Y83 6.3.2.- Q00987 24704029 QIPASEQETLVRPKPELLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLV 4ot8 A 2.00 BS01 PLP A 1 S98 G99 S100 H127 S176 D201 A203 H204 T227 H229 K230 S97 G98 S99 H126 S175 D200 A202 H203 T226 H228 K229 2.1.2.1 B4ECY9 FDRAQSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4ot8 A 2.00 BS02 SER A 1 S36 H127 H204 K230 R361 S35 H126 H203 K229 R360 2.1.2.1 B4ECY9 FDRAQSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4ot8 A 2.00 BS03 SER A 2 E58 Y66 E57 Y65 2.1.2.1 B4ECY9 FDRAQSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4ot8 B 2.00 BS02 SER B 1 S36 H127 S176 H204 K230 R361 S32 H123 S172 H200 K226 R357 2.1.2.1 B4ECY9 AQSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4ot8 B 2.00 BS03 SER B 2 Y56 E58 Y66 Y52 E54 Y62 2.1.2.1 B4ECY9 AQSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4otl A 2.00 BS03 PLP C 1 Y56 G261 Y50 G255 2.1.2.1 B4ECY9 STIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4otl A 2.00 BS04 GLY C 1 Y56 Y66 Y50 Y60 2.1.2.1 B4ECY9 STIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4otl B 2.00 BS02 GLY B 1 S36 H204 K230 R361 S30 H198 K224 R355 2.1.2.1 B4ECY9 STIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLIVAGASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQVAELTKRFPVYR 4ovz A 2.50 BS02 P85 A 1 L163 G164 D165 P248 P249 Y265 N268 Y269 Q270 Y274 T302 L155 G156 D157 P240 P241 Y257 N260 Y261 Q262 Y266 T294 3.4.19.12,3.4.22.69 P0C6U8 24568342 FTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTT 4ow0 A 2.10 BS02 S88 A 1 L163 G164 D165 P249 Y265 Y269 Q270 Y274 T302 L160 G161 D162 P246 Y262 Y266 Q267 Y271 T299 3.4.19.12,3.4.22.69 P0C6U8 24568342 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTI 4owm B 1.99 BS03 PRP B 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 A140 A141 G146 G147 E252 V83 G84 G86 G87 N94 S96 T97 K112 N115 A117 A118 G121 G122 E227 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAALSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQILE 4owm B 1.99 BS04 3F0 B 1 A179 P180 H183 Y186 R187 A190 R194 A154 P155 H158 Y161 R162 A165 R169 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAALSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQILE 4own A 2.11 BS03 POP A 1 V106 G107 N117 S119 T120 K135 E252 V83 G84 N94 S96 T97 K112 E226 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRALSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4own A 2.11 BS04 5RG A 1 V106 G107 T108 H136 G137 N138 A179 R193 G206 V83 G84 T85 H113 G114 N115 A153 R167 G180 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRALSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4own B 2.11 BS05 5RG B 2 V106 G107 T108 H136 N138 A179 R193 G206 V83 G84 T85 H113 N115 A155 R169 G182 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQIL 4owq A 1.89 BS04 3M0 A 1 A179 P180 H183 Y186 A190 R194 A156 P157 H160 Y163 A167 R171 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4owq B 1.89 BS02 PRP B 1 V106 G107 G109 G110 N117 S119 T120 K135 G146 G147 E252 V83 G84 G86 G87 N94 S96 T97 K112 G120 G121 E226 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRALSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQIL 4owu A 1.89 BS03 PRP A 1 V106 G107 G109 G110 N117 S119 T120 K135 N138 R139 A141 S142 S143 G146 G147 E252 V83 G84 G86 G87 N94 S96 T97 K112 N115 R116 A118 S119 S120 G123 G124 E229 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4owv B 1.90 BS01 BE2 B 1 N138 A179 H183 Y186 R187 A190 N113 A154 H158 Y161 R162 A165 2.4.2.18 P9WFX5 24712732 VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI 4p5s A 1.02 BS01 CU1 A 1 H53 C92 M98 H53 C92 M98 P22364 24704124 DKATIPSESPFAAAEVADGAIVVDIAKMKYETPELHVKVGDTVTYINREAMPHNVHFVAGVLGEAALKGPMMKKEQAYSLTFTEAGTYDYHCTPHPFMRGKVVVE 4psi A 2.45 BS01 III D 1 P52 K57 K64 F66 D111 A112 K113 M165 K166 N167 R168 I174 P16 K21 K28 F30 D62 A63 K64 M116 K117 N118 R119 I125 Q9NWS0 24656813 AHSAALEVLFQGPGQPGFCIKTNSSEGKVFINICHSPSIPPPADVTEFRIPMSLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSI 4psi B 2.45 BS01 III E 1 P52 K57 K64 D111 A112 K113 R163 M165 K166 N167 R168 I174 P14 K19 K26 D60 A61 K62 R112 M114 K115 N116 R117 I123 Q9NWS0 24656813 AHSAALEVLFPGQPGFCIKTNSSEGKVFINICHSPSIPPPADVTEFRIPMSLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNSDFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSI 4puz A 2.08 BS01 CG9 A 1 L377 G378 S379 F382 V385 A400 M448 E449 A451 E452 G454 P455 L501 D512 L15 G16 S17 F20 V23 A38 M81 E82 A84 E85 G87 P88 L134 D145 2.7.10.2 P43405 VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDV 4pv8 A 2.31 BS01 III E 1 Y7 V9 E24 E63 K66 N70 S73 F74 D77 L81 Y84 V97 Q114 Y116 T143 K146 W147 E152 R155 L156 Y159 W167 Y171 Y7 V9 E24 E63 K66 N70 S73 F74 D77 L81 Y84 V97 Q114 Y116 T143 K146 W147 E152 R155 L156 Y159 W167 Y171 P01901 GPHSLRYFVTAVSRPGLGEPRYMEVGYVDDTEFVRFDSDAENPRYEPRARWMEQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQSKGGSHTIQVISGCEVGSDGRLLRGYQQYAYDGCDYIALNEDLKTWTAADMAALITKHKWEQAGEAERLRAYLEGTCVEWLRRYLKNGNATLLRTDSPKAHVTHHSRPEDKVTLRCWALGFYPADITLTWQLNGEELIQDMELVETRPAGDGTFQKWASVVVPLGKEQYYTCHVYHQGLPEPLTLRWEPPP 4pv9 A 2.00 BS01 III E 1 Y7 V9 E24 R62 E63 K66 N70 S73 F74 D77 T80 L81 Y84 V97 S99 Q114 Y116 T143 K146 W147 E152 R155 Y159 T163 W167 Y171 Y7 V9 E24 R62 E63 K66 N70 S73 F74 D77 T80 L81 Y84 V97 S99 Q114 Y116 T143 K146 W147 E152 R155 Y159 T163 W167 Y171 P01901 GPHSLRYFVTAVSRPGLGEPRYMEVGYVDDTEFVRFDSDAENPRYEPRARWMEQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQSKGGSHTIQVISGCEVGSDGRLLRGYQQYAYDGCDYIALNEDLKTWTAADMAALITKHKWEQAGEAERLRAYLEGTCVEWLRRYLKNGNATLLRTDSPKAHVTHHSRPEDKVTLRCWALGFYPADITLTWQLNGEELIQDMELVETRPAGDGTFQKWASVVVPLGKEQYYTCHVYHQGLPEPLTLRWEPPP 4px6 A 1.60 BS01 2X6 A 1 S379 A400 V433 M448 E449 M450 A451 E452 G454 P455 R498 N499 L501 D512 S16 A35 V63 M78 E79 M80 A81 E82 G84 P85 R128 N129 L131 D142 2.7.10.2 P43405 24726806 YLDRKLLTLEDKELGSGNFGTVKKGYYQMVVKTVAVKILKPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVTDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNE 4pxy A 1.50 BS01 ZN A 1 H48 H120 E178 H234 H25 H97 E155 H211 A7V213 YPANYAKAPRFKALIYYTQHAEEAHVQFAEQATTFFKKLNYGDGFVLDITTDFSKYPYEKLKEYNVIIMLNTSPNTKAERDAFEQYMENGGGWVGFHAAAYNDKNTHWPWFVKFLGGGVFYCNNWPPQPVLVEVDNEEHPVTKNLPASFVAPASEWYQWTPSPRQNKDVEVLLSLSPKNYPLGIKDVVNFGDFPIVWSNKNYRMIYLNMGHGDEEFIDGTQNLLLVNAFRWVVSKDKSGNPFLK 4pxy A 1.50 BS02 ZN A 2 I240 D241 I217 D218 A7V213 YPANYAKAPRFKALIYYTQHAEEAHVQFAEQATTFFKKLNYGDGFVLDITTDFSKYPYEKLKEYNVIIMLNTSPNTKAERDAFEQYMENGGGWVGFHAAAYNDKNTHWPWFVKFLGGGVFYCNNWPPQPVLVEVDNEEHPVTKNLPASFVAPASEWYQWTPSPRQNKDVEVLLSLSPKNYPLGIKDVVNFGDFPIVWSNKNYRMIYLNMGHGDEEFIDGTQNLLLVNAFRWVVSKDKSGNPFLK 4pyh A 1.65 BS01 GLC A 1 H88 F140 H3 F55 3.1.3.- Q9FEB5 GSHMYRHELGMNYNFIRPDLIVGSCLQTPEDVDKLRKIGVKTIFCLQQDPDLEYFGVDISSIQAYAKKYSDIQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKRSCFPKLDAIRNATIDILTGLKRKTVTLTLKDKGFSRVEISGLDIGWGQRIPLTLDKGTGFWILKRELPEGQFEYKYIIDGEWTHNEAEPFIGPNKDGHTNNYAKVVDDPTSVDGTTRERLSSEDPELLEEERSKLIQFLETCSEAE 4pyh A 1.65 BS02 GLC A 2 H88 M89 Y90 D166 F167 A200 M202 H3 M4 Y5 D81 F82 A115 M117 3.1.3.- Q9FEB5 GSHMYRHELGMNYNFIRPDLIVGSCLQTPEDVDKLRKIGVKTIFCLQQDPDLEYFGVDISSIQAYAKKYSDIQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKRSCFPKLDAIRNATIDILTGLKRKTVTLTLKDKGFSRVEISGLDIGWGQRIPLTLDKGTGFWILKRELPEGQFEYKYIIDGEWTHNEAEPFIGPNKDGHTNNYAKVVDDPTSVDGTTRERLSSEDPELLEEERSKLIQFLETCSEAE 4pyh A 1.65 BS03 GLC A 3 G86 S87 F235 K237 G1 S2 F150 K152 3.1.3.- Q9FEB5 GSHMYRHELGMNYNFIRPDLIVGSCLQTPEDVDKLRKIGVKTIFCLQQDPDLEYFGVDISSIQAYAKKYSDIQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKRSCFPKLDAIRNATIDILTGLKRKTVTLTLKDKGFSRVEISGLDIGWGQRIPLTLDKGTGFWILKRELPEGQFEYKYIIDGEWTHNEAEPFIGPNKDGHTNNYAKVVDDPTSVDGTTRERLSSEDPELLEEERSKLIQFLETCSEAE 4pyh A 1.65 BS04 GLC A 4 F167 K237 W278 N326 D328 F82 K152 W193 N241 D243 3.1.3.- Q9FEB5 GSHMYRHELGMNYNFIRPDLIVGSCLQTPEDVDKLRKIGVKTIFCLQQDPDLEYFGVDISSIQAYAKKYSDIQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKRSCFPKLDAIRNATIDILTGLKRKTVTLTLKDKGFSRVEISGLDIGWGQRIPLTLDKGTGFWILKRELPEGQFEYKYIIDGEWTHNEAEPFIGPNKDGHTNNYAKVVDDPTSVDGTTRERLSSEDPELLEEERSKLIQFLETCSEAE 4pyh A 1.65 BS05 GLC A 5 F167 W278 W314 N332 F82 W193 W229 N247 3.1.3.- Q9FEB5 GSHMYRHELGMNYNFIRPDLIVGSCLQTPEDVDKLRKIGVKTIFCLQQDPDLEYFGVDISSIQAYAKKYSDIQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKRSCFPKLDAIRNATIDILTGLKRKTVTLTLKDKGFSRVEISGLDIGWGQRIPLTLDKGTGFWILKRELPEGQFEYKYIIDGEWTHNEAEPFIGPNKDGHTNNYAKVVDDPTSVDGTTRERLSSEDPELLEEERSKLIQFLETCSEAE 4pyh A 1.65 BS06 GLC A 6 K307 W314 H330 K222 W229 H245 3.1.3.- Q9FEB5 GSHMYRHELGMNYNFIRPDLIVGSCLQTPEDVDKLRKIGVKTIFCLQQDPDLEYFGVDISSIQAYAKKYSDIQHIRCEIRDFDAFDLRMRLPAVVGTLYKAVKRNGGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKRSCFPKLDAIRNATIDILTGLKRKTVTLTLKDKGFSRVEISGLDIGWGQRIPLTLDKGTGFWILKRELPEGQFEYKYIIDGEWTHNEAEPFIGPNKDGHTNNYAKVVDDPTSVDGTTRERLSSEDPELLEEERSKLIQFLETCSEAE 4pyr A 1.45 BS01 GSH A 1 L168 N169 S170 S185 L186 I187 R219 L335 L86 N87 S88 S103 L104 I105 R137 L253 Q7P0B4 KVRIGVILPAESSALGEAAAVVRSGVEAAAQVDQSAELYSVDATGDNVVERYRAAVADGVNVVIGPLSRDSIVKLAPSVTVPTLALNSVGREAAANPKLYSLSLIVEGEARQLARLMRDDSRAAPLLVVGGDALSQRLGKAFADEWRAAAGKPVRQMAFDANDMAPLLQAAGQADAVALALDVAQAARLKSALTPDVPVYGTSQLNVGGMQPELAGVRFIDMPWFLMPAHPAVQRYPRPAAPLTRQTERLYALGIDAYRLAVQLAGSRSGAAVRLDGVTGDLKLGRDRAFERQLPAGVM 4pzf A 2.20 BS01 FAD A 1 L99 S101 G102 G103 H104 S105 Y106 S110 L122 S141 A164 C166 V169 G170 G172 G173 H174 F180 G225 G226 G229 A230 I231 Y456 N458 L74 S76 G77 G78 H79 S80 Y81 S85 L97 S116 A139 C141 V144 G145 G147 G148 H149 F155 G200 G201 G204 A205 I206 Y431 N433 1.21.3.3 P30986 DLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAAWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFD 4q04 A 1.90 BS01 MG A 1 D61 D63 S65 T67 D53 D55 S57 T59 Q9GSV7 CLWNLQPIQGSWMGAACIYQMPPSVRNTWWFPLLNTIPLDQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALRMMRIFDTDFNGHISFYEFMAMYKFMELAYNLFVMNDRNRSGTLEPHEILPALQQLGFYINQRTSLLLHRLFARGMAFCDLNCWIAICAFAAQTRSAYQMIFMNPYYGPMKPFNPMEFGKFLDVVTSLLE 4q0k A 1.34 BS01 GA3 A 1 Q22 V30 L34 F56 F58 Q68 F103 S140 T141 Y144 Q22 V30 L34 F56 F58 Q68 F103 S140 T141 Y144 G7J032 MIKEFNTQTTLNVGLEALWAAQSKDITLVVPKVLPNIVKDVQVIEGDGGVGTKLIFNFLPGIAPVNYQREVITEYDELSHTIGLQVVEGGYLNQGLSYYKTTFQFSAISENKTLVNVKISYDHESELIEEKVKPTKTSESTLFYLGQLEKFLLN 4q12 A 2.85 BS01 UDP A 1 N10 H63 K65 F93 Q95 S135 Y139 H205 F208 N210 N11 H64 K66 F94 Q96 S136 Y140 H206 F209 N211 P9WKZ2 SMVTILILTDNVHAHALAVDLQARHGDMDVYQSPIGQLPGVPRCDVAERVAEIVERYDLVLSFHCKQRFPAALIDGVRCVNVHPGFNPYNRGWFPQVFSIIDGQKVGVTIHEIDDQLDHGPIIAQRECAIESWDSSGSVYARLMDIERELVLEHFDAIRDGSYTAKSPATEGNLNLKKDFEQLRRLDLNERGTFGHFLNRLRALTHDDFRNAWFVDASGRKVFVRVVLEPEK 4q22 A 1.93 BS01 NAG A 1 W114 A159 W160 W97 A142 W143 3.2.1.14 A8GFD6 AHAASYLSVGYFNGGGDVTAGPGGDINKLDVTQITHLNYSFGLIYNDEKQETNPALKDPSRLHQIYLSPKVMADLQLLPVLRKQNPELKVLLSVGGWGARGFSGAAATAESRAVFIRSVQQVIKQYHLDGIDLDWEYPVNGAWGLVESQPADRANFTLLLAELHKALDKGKLLTIAVGANVKSPQEWVDVKGIAPYLDYINLMTYDMAYGTQYFNSNLYDSKQWPTVAAADRYSANFVVDNYLAAGLKPAQLNLGIGFYGRVPKRATEPGIDWDKADAAKNPVTQPYFTARETAVFKAMGLDLTKDSYFKYNDIVSKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKPLFAISYENPRSVALKADYIKSKGLGGAMFWEYGADDNNRLAHQLAESLGI 4q39 A 2.20 BS01 NAI A 1 A2 N121 T125 V147 G150 K151 V152 Y170 D171 A172 L176 A203 T204 P205 C206 T209 P224 I226 E245 P246 L247 A2 N121 T125 V147 G150 K151 V152 Y170 D171 A172 L176 A203 T204 P205 C206 T209 P224 I226 E245 P246 L247 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q39 A 2.20 BS03 PYH A 1 L3 L4 P52 V53 G58 I59 I60 F63 A103 D104 F108 L3 L4 P52 V53 G58 I59 I60 F63 A103 D104 F108 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3a A 2.20 BS03 2YC A 1 L3 L4 V53 G58 I59 I60 F63 A103 F108 N121 P246 L3 L4 V53 G58 I59 I60 F63 A103 F108 N121 P246 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3a B 2.20 BS01 NAI B 1 A2 N121 T125 G150 K151 V152 Y170 D171 A172 D173 A203 T204 P205 C206 T209 P224 E245 P246 L247 A2 N121 T125 G150 K151 V152 Y170 D171 A172 D173 A203 T204 P205 C206 T209 P224 E245 P246 L247 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3a C 2.20 BS03 2YC C 1 L3 L4 P52 V53 G58 I59 I60 F63 A103 F108 N121 L4 L5 P53 V54 G59 I60 I61 F64 A104 F109 N122 1.4.1.- Q46E80 SMALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3a D 2.20 BS01 NAI D 1 A2 N121 T125 V147 G150 K151 V152 Y170 D171 A172 A203 T204 P205 T209 P224 E245 P246 L247 A2 N121 T125 V147 G150 K151 V152 Y170 D171 A172 A203 T204 P205 T209 P224 E245 P246 L247 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3a D 2.20 BS03 2YC D 1 L3 L4 P52 V53 G58 I59 I60 F63 A103 N121 P246 L3 L4 P52 V53 G58 I59 I60 F63 A103 N121 P246 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3b A 1.90 BS03 2YF A 1 L3 L4 V53 G58 I59 I60 F63 A103 D104 N121 P246 L247 L4 L5 V54 G59 I60 I61 F64 A104 D105 N122 P247 L248 1.4.1.- Q46E80 SMALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3b C 1.90 BS03 2YF C 1 L3 L4 P52 V53 G58 I59 I60 F63 A103 L247 L4 L5 P53 V54 G59 I60 I61 F64 A104 L248 1.4.1.- Q46E80 SMALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3c C 2.10 BS03 2YG C 1 L3 L4 P52 V53 G58 I59 I60 F63 A103 L3 L4 P52 V53 G58 I59 I60 F63 A103 1.4.1.- Q46E80 MALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3c D 2.10 BS01 NAD D 1 N121 V147 G150 K151 V152 Y170 D171 A172 A203 T204 P205 T209 P224 E245 P246 N120 V146 G149 K150 V151 Y169 D170 A171 A202 T203 P204 T208 P223 E244 P245 1.4.1.- Q46E80 ALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3d A 2.20 BS03 2YH A 1 L3 V53 G58 I59 I60 F63 A103 D104 D105 R106 T107 N121 Q122 L2 V52 G57 I58 I59 F62 A102 D103 D104 R105 T106 N120 Q121 1.4.1.- Q46E80 ALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3d B 2.20 BS03 2YH B 1 L3 P52 V53 G58 I59 I60 F63 A103 D104 D105 R106 Q122 L2 P51 V52 G57 I58 I59 F62 A102 D103 D104 R105 Q121 1.4.1.- Q46E80 ALLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3d C 2.20 BS03 2YH C 1 P52 V53 G58 I59 I60 F63 A103 D104 D105 R106 P41 V42 G47 I48 I49 F52 A92 D93 D94 R95 1.4.1.- Q46E80 INMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3d D 2.20 BS01 NAD D 1 N121 T125 V147 G150 K151 V152 Y170 D171 A172 A203 T204 P205 C206 T209 P224 G225 I226 E245 P246 N118 T122 V144 G147 K148 V149 Y167 D168 A169 A200 T201 P202 C203 T206 P221 G222 I223 E242 P243 1.4.1.- Q46E80 LTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3e A 2.20 BS03 2YJ A 1 V53 I60 F63 A103 D105 I226 V51 I54 F57 A97 D99 I220 1.4.1.- Q46E80 LLTPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL 4q3e B 2.20 BS03 2YJ B 1 P52 V53 I60 F63 A103 D104 P48 V49 I56 F59 A99 D100 1.4.1.- Q46E80 TPDDLININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPVTSGNGIIGNFSASLHAITQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFLAHNLKNGKMANNQPCTGIIYAEIASRYLKADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERATSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL