2mfq A BS01 III B 1 V26 D27 D28 D29 G30 Y59 L60 C61 L62 R63 R64 Y65 G66 Y67 D68 S69 N70 L71 F72 S73 G77 R78 I86 A88 F89 K90 F98 Q102 M105 S109 I110 P116 V19 D20 D21 D22 G23 Y52 L53 C54 L55 R56 R57 Y58 G59 Y60 D61 S62 N63 L64 F65 S66 G70 R71 I79 A81 F82 K83 F91 Q95 M98 S102 I103 P109 Q8WU20 24470253 SHMDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNN 2mg5 A BS01 III B 1 E11 F12 A15 L18 F19 V35 M36 S38 L39 Q41 L48 M51 F68 M72 K75 E84 E87 A88 V91 F92 I100 E104 L105 M109 M124 I125 E127 A128 V136 F141 M144 M145 K148 E11 F12 A15 L18 F19 V35 M36 S38 L39 Q41 L48 M51 F68 M72 K75 E84 E87 A88 V91 F92 I100 E104 L105 M109 M124 I125 E127 A128 V136 F141 M144 M145 K148 P62158 24495081 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 2mkr A BS01 III B 1 Q49 A50 T51 P52 S55 K57 M59 L60 R61 R86 M88 Q49 A50 T51 P52 S55 K57 M59 L60 R61 R86 M88 P32776 PSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDAD 3w5k B 2.60 BS01 ZN B 1 C156 C159 K161 H172 H176 C4 C7 K9 H20 H24 O95863 AFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR 3w5k B 2.60 BS02 ZN B 2 C182 T184 C185 H198 H202 C30 T32 C33 H46 H50 O95863 AFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR 3w5k B 2.60 BS03 ZN B 3 C210 C213 H226 H230 C56 C59 H72 H76 O95863 AFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR 3w5k B 2.60 BS04 ZN B 4 C238 C241 H254 C259 C84 C87 H100 C105 O95863 AFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQACARTFSRMSLLHKHQESGCSGCPR 3w6y A 2.68 BS01 W6Y A 1 K43 N53 N67 M69 G70 L71 N127 P131 N194 S195 K214 K44 N54 N68 M70 G71 L72 N128 P132 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w6y A 2.68 BS02 FMN A 1 A18 A19 G20 K43 S44 Y58 N67 N127 K164 V193 N194 S195 G221 G222 I225 C248 G249 G250 G271 T272 A19 A20 G21 K44 S45 Y59 N68 N128 K165 V194 N195 S196 G222 G223 I226 C249 G250 G251 G272 T273 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w6y B 2.68 BS01 W6Y B 1 K43 N67 M69 G70 L71 N127 S129 P131 N194 S195 K214 K44 N68 M70 G71 L72 N128 S130 P132 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w70 A 2.60 BS02 FMN A 1 A18 A19 G20 K43 S44 Y58 N67 M69 N127 K164 V193 N194 G221 G222 I225 C248 G250 G271 T272 A19 A20 G21 K44 S45 Y59 N68 M70 N128 K165 V194 N195 G222 G223 I226 C249 G251 G272 T273 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w70 B 2.60 BS01 W70 B 1 K43 R50 N67 M69 G70 L71 S99 N127 N194 S195 K44 R51 N68 M70 G71 L72 S100 N128 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w70 B 2.60 BS02 FMN B 1 A18 A19 G20 K43 S44 Y58 N67 M69 N127 K164 V193 N194 G221 G222 C248 G249 G250 G271 T272 A19 A20 G21 K44 S45 Y59 N68 M70 N128 K165 V194 N195 G222 G223 C249 G250 G251 G272 T273 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w72 A 1.55 BS01 W7B A 1 K43 R50 N67 M69 G70 L71 S99 L101 N127 C130 P131 N194 S195 K44 R51 N68 M70 G71 L72 S100 L102 N128 C131 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w72 B 1.55 BS01 W7B B 1 N67 M69 G70 L71 N127 P131 N194 S195 N68 M70 G71 L72 N128 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w73 A 1.78 BS01 W73 A 1 K43 N67 S68 M69 G70 L71 L101 N127 S129 N194 S195 K44 N68 S69 M70 G71 L72 L102 N128 S130 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w75 A 1.47 BS01 W75 A 1 K43 N67 S68 M69 G70 L71 N127 S129 C130 P131 Q138 N194 S195 K44 N68 S69 M70 G71 L72 N128 S130 C131 P132 Q139 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7c B 1.75 BS01 W7C B 1 K43 R50 N67 S68 M69 G70 L71 N127 N194 S195 K214 K44 R51 N68 S69 M70 G71 L72 N128 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7d A 1.52 BS01 W7D A 1 K43 R50 N53 N67 M69 G70 L71 N127 P131 N194 S195 K44 R51 N54 N68 M70 G71 L72 N128 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7k A 1.61 BS02 W7K A 1 K43 N53 N67 M69 G70 L71 N127 S129 P131 N194 S195 K44 N54 N68 M70 G71 L72 N128 S130 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7l A 1.88 BS01 W7L A 1 R50 N67 M69 G70 L71 N127 P131 N194 S195 R51 N68 M70 G71 L72 N128 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7m A 2.40 BS01 W7M A 1 K43 R50 N53 N67 S68 M69 G70 L71 N127 P131 N194 S195 K214 K44 R51 N54 N68 S69 M70 G71 L72 N128 P132 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7n A 2.39 BS02 FMN A 1 A18 A19 G20 K43 S44 Y58 N67 N127 K164 V193 N194 G222 I225 C248 G249 G250 G271 T272 A19 A20 G21 K44 S45 Y59 N68 N128 K165 V194 N195 G223 I226 C249 G250 G251 G272 T273 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7o B 1.68 BS01 W7O B 1 K43 N67 M69 G70 L71 N127 C130 P131 N194 S195 K44 N68 M70 G71 L72 N128 C131 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w7q A 1.83 BS01 W7Q A 1 K43 R50 N53 N67 S68 M69 G70 L71 N127 S129 P131 N194 S195 K44 R51 N54 N68 S69 M70 G71 L72 N128 S130 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3wdr A 1.40 BS01 BGC A 1 F86 E92 F72 E78 3.2.1.78 H7CGE2 QDWNISSSPVTPSPSAGAQKLYSFLVQNFQKKIISGAMTLQGGDESAQTKEPDWLQQNAGHRPALVGLDFMFQTGKGEEWYYNDSRFSKQVVNGAKSYWQKGGIPALCWHWRDPSKDTDAFYSPSSGNSATQFDADQAVKSGTAENKAILQDLAVIADQLQDLRDAGVAVLWRPLHEASGKWFWWGYKGADALKKLWKIEFDYFVKERNLNNLIWVFTAGTPIEGIADWYPGDDMVDVIGMDIYATQGDHATQQDYFNQCKSIFKGRKIVAMSECGSVPEPDLAAPWSFFMPWYNNYCIPEGSNPYNSLEFWKKTMSSSLVITLDNMPGW 3wdr A 1.40 BS02 BGC A 2 M85 R126 F135 M71 R112 F121 3.2.1.78 H7CGE2 QDWNISSSPVTPSPSAGAQKLYSFLVQNFQKKIISGAMTLQGGDESAQTKEPDWLQQNAGHRPALVGLDFMFQTGKGEEWYYNDSRFSKQVVNGAKSYWQKGGIPALCWHWRDPSKDTDAFYSPSSGNSATQFDADQAVKSGTAENKAILQDLAVIADQLQDLRDAGVAVLWRPLHEASGKWFWWGYKGADALKKLWKIEFDYFVKERNLNNLIWVFTAGTPIEGIADWYPGDDMVDVIGMDIYATQGDHATQQDYFNQCKSIFKGRKIVAMSECGSVPEPDLAAPWSFFMPWYNNYCIPEGSNPYNSLEFWKKTMSSSLVITLDNMPGW 3wdr A 1.40 BS03 BCT A 1 H124 H190 E191 F197 E288 H110 H176 E177 F183 E274 3.2.1.78 H7CGE2 QDWNISSSPVTPSPSAGAQKLYSFLVQNFQKKIISGAMTLQGGDESAQTKEPDWLQQNAGHRPALVGLDFMFQTGKGEEWYYNDSRFSKQVVNGAKSYWQKGGIPALCWHWRDPSKDTDAFYSPSSGNSATQFDADQAVKSGTAENKAILQDLAVIADQLQDLRDAGVAVLWRPLHEASGKWFWWGYKGADALKKLWKIEFDYFVKERNLNNLIWVFTAGTPIEGIADWYPGDDMVDVIGMDIYATQGDHATQQDYFNQCKSIFKGRKIVAMSECGSVPEPDLAAPWSFFMPWYNNYCIPEGSNPYNSLEFWKKTMSSSLVITLDNMPGW 3wnr A 2.01 BS01 9BE A 1 P2 M3 Y37 I65 F114 P1 M2 Y36 I64 F113 5.3.2.1,5.3.3.12 P14174 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 3wns A 1.66 BS01 9AI A 1 P2 M3 Y37 V107 P1 M2 Y36 V106 5.3.2.1,5.3.3.12 P14174 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 3wns C 1.66 BS02 9AI C 1 P2 M3 H63 V107 P1 M2 H62 V106 5.3.2.1,5.3.3.12 P14174 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 3wnt C 2.07 BS02 9BE C 1 P2 M3 H63 S64 I65 M102 V107 P1 M2 H62 S63 I64 M101 V106 5.3.2.1,5.3.3.12 P14174 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 3wr1 A 3.50 BS01 HEM A 1 Y42 F43 H45 H58 K61 V62 A65 L66 L83 H87 L91 V93 N97 F98 L101 M129 V132 L136 Y42 F43 H45 H58 K61 V62 A65 L66 L83 H87 L91 V93 N97 F98 L101 M129 V132 L136 P10780 VLSASDKTNVKGVFAKVGGSAEAYGAETLERMFTAYPQTKTYFPHFDLHHGSAQIKAHGKKVAAALVEAANHIDDIAGALSKLSDLHAQKLRVDPVNFKLLGHCFLVVVAIHHPTLLTPEVHASLDKFMCAVAKELTAKYR 3wr1 B 3.50 BS01 HEM B 1 F41 F42 F45 H63 K66 V67 S70 F71 F85 L88 L91 H92 L96 V98 N102 F103 L106 L141 F41 F42 F45 H63 K66 V67 S70 F71 F85 L88 L91 H92 L96 V98 N102 F103 L106 L141 P10782 VHWTAEEKQLITGLWGKVNVAECGAEALARLLIVYPWTQRFFASFGNLSSATAITGNPMVRAHGKKVLTSFGEAVKNLDNIKATFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFAKDFTPECQAAWQKLVGAVAHALARKYH 4c7k A 1.91 BS02 DZL A 1 T124 L126 S170 L171 Y177 V180 Y183 G216 T222 A223 A226 M233 T99 L101 S145 L146 Y152 V155 Y158 G191 T197 A198 A201 M208 1.1.1.146 P28845 24422550 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTS 4c7k C 1.91 BS02 DZL C 1 I121 T124 L126 S170 L171 Y177 V180 Y183 G216 L217 T222 A226 M233 I96 T99 L101 S145 L146 Y152 V155 Y158 G191 L192 T197 A201 M208 1.1.1.146 P28845 24422550 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPLVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSRWTTLLIRNPSRKILEELYSTS 4cki A 2.12 BS01 ADN A 1 L730 G731 E732 V738 A756 V804 E805 Y806 A807 S811 L881 L31 G32 E33 V39 A57 V105 E106 Y107 A108 S112 L163 2.7.10.1 P07949 24560924 GPLSLSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWTAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRR 4clk A 2.20 BS01 APC A 1 D47 I48 S49 G50 F51 T52 A97 G98 D99 F336 F338 L345 T405 V406 V411 N412 A415 R416 D47 I48 S49 G50 F51 T52 A97 G98 D99 F330 F332 L339 T399 V400 V405 N406 A409 R410 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRT 4clk A 2.20 BS02 CA A 1 D47 I48 D99 D47 I48 D99 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRT 4cll A 1.70 BS01 BCT A 1 K95 L166 V167 V172 R176 F336 M337 K95 L157 V158 V163 R167 F327 M328 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEK 4clp A 1.90 BS01 CMP A 1 R199 I202 E203 I204 E205 S206 R192 I195 E196 I197 E198 S199 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFELDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTE 4clp A 1.90 BS02 CMP A 2 A97 G98 F336 F338 L345 T405 V406 V411 N412 A415 R416 A97 G98 F329 F331 L338 T398 V399 V404 N405 A408 R409 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFELDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTE 4cls A 1.85 BS01 MG A 1 D47 D99 D47 D99 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTE 4cls A 1.85 BS02 POP A 1 D47 I48 S49 G50 F51 T52 D99 K144 N412 D47 I48 S49 G50 F51 T52 D99 K136 N404 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTE 4clt A 1.95 BS02 CMP A 1 W194 R199 I202 E203 I204 E205 S206 W187 R192 I195 E196 I197 E198 S199 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFGLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKV 4clt A 1.95 BS03 CMP A 2 A97 G98 R176 F336 L345 V406 V411 N412 A415 R416 A97 G98 R169 F329 L338 V399 V404 N405 A408 R409 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFGLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKV 4clt A 1.95 BS04 POP A 1 D47 S49 G50 F51 T52 D99 K144 D47 S49 G50 F51 T52 D99 K137 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFGLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKV 4clw A 2.15 BS01 APC A 1 D47 S49 G50 F51 T52 A97 G98 D99 R176 F336 F338 L345 V406 V411 N412 A415 R416 D47 S49 G50 F51 T52 A97 G98 D99 R168 F328 F330 L337 V398 V403 N404 A407 R408 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRT 4cly A 2.05 BS01 BSY A 1 K95 L102 V167 F336 M337 K95 L102 V160 F329 M330 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETQIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEK 4clz A 1.90 BS01 4DS A 1 F8 D10 V14 R15 A18 R250 A252 C253 Q276 I277 N279 Q281 Q283 T399 V400 F8 D10 V14 R15 A18 R240 A242 C243 Q266 I267 N269 Q271 Q273 T389 V390 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEK 4clz A 1.90 BS02 4DS A 2 F45 K95 F96 A97 L101 L102 R176 F336 F338 D339 R416 M419 Y420 F45 K95 F96 A97 L101 L102 R166 F326 F328 D329 R406 M409 Y410 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEK 4clz A 1.90 BS03 4DS A 3 F51 M54 K57 F58 M62 Y63 I74 H78 F51 M54 K57 F58 M62 Y63 I74 H78 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEK 4cm0 A 3.20 BS01 APC A 1 D47 I48 S49 G50 F51 T52 A97 G98 D99 K144 F336 V406 V411 N412 A415 R416 G452 D47 I48 S49 G50 F51 T52 A97 G98 D99 K140 F332 V400 V405 N406 A409 R410 G446 4.6.1.1 Q96PN6 24567411 MNTPKEEFQDWPIVRIAAHLPDLIVYGHFSPERPFMDYFDGVLMFVDISGFTAMTEKFSSAMYMDRGAEQLVEILNYHISAIVEKVLIFGGDILKFAGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETQGLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLACTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEIGPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFEKVPDELTHALECAMDIFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVTCDSVTYNGSNLPPYFFKELPKKVMKGVADSGPLYQYWGRTE 4coo A 2.00 BS01 HEM A 1 S50 R51 C52 T53 W54 R58 E62 S63 P64 H65 A226 P229 L230 Y233 R266 S8 R9 C10 T11 W12 R16 E20 S21 P22 H23 A184 P187 L188 Y191 R224 4.2.1.22 P35520 WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQMVFGVVTAIDLLNFVAAQER 4coo A 2.00 BS02 PLP A 1 K119 N149 S254 V255 G256 T257 G258 T260 E304 G305 I306 S349 P375 D376 K77 N107 S212 V213 G214 T215 G216 T218 E262 G263 I264 S307 P333 D334 4.2.1.22 P35520 WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQMVFGVVTAIDLLNFVAAQER 4coo B 2.00 BS01 HEM B 1 S50 R51 C52 T53 W54 R58 P59 E62 S63 P64 H65 A226 P229 L230 Y233 R266 V314 S8 R9 C10 T11 W12 R16 P17 E20 S21 P22 H23 A184 P187 L188 Y191 R224 V272 4.2.1.22 P35520 WIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQQMVFGVVTAIDLLNFVAAQER 4cos A 1.67 BS01 ZN A 1 C255 C258 C274 H278 C170 C173 C189 H193 Q9ULU4 RNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDQEKVKL 4cos A 1.67 BS02 ZN A 2 C91 C94 H111 C114 C6 C9 H26 C29 Q9ULU4 RNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDQEKVKL 4cos A 1.67 BS03 ZN A 3 C103 C106 C127 C130 C18 C21 C42 C45 Q9ULU4 RNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDQEKVKL 4iy0 A 1.90 BS01 ADP A 1 T451 D455 C456 F457 Y478 T479 R480 P482 I566 T568 E570 D571 T23 D27 C28 F29 Y50 T51 R52 P54 I138 T140 E142 D143 Q9H8M5 KEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSE 4j6b A 2.20 BS01 PLO A 1 M84 F179 Q239 A240 A243 A244 T248 V291 L294 Q398 M81 F176 Q234 A235 A238 A239 T243 V286 L289 Q393 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6b A 2.20 BS02 HEM A 1 L55 M91 F92 H99 R103 I158 L241 A244 G245 T248 T249 P290 V291 L294 R297 Y320 S349 F350 G351 H355 C357 P358 G359 L362 A363 L52 M88 F89 H96 R100 I155 L236 A239 G240 T243 T244 P285 V286 L289 R292 Y315 S344 F345 G346 H350 C352 P353 G354 L357 A358 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6b A 2.20 BS03 MG A 1 H6 D8 H3 D5 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6c A 1.90 BS01 STR A 1 M84 F92 F179 A240 A243 A244 T248 V291 L294 Q398 M81 F89 F176 A237 A240 A241 T245 V288 L291 Q395 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6c A 1.90 BS02 HEM A 1 L55 M91 F92 H99 R103 I158 L241 A244 G245 T248 T249 L285 P290 L294 R297 Y320 S349 F350 G351 H355 C357 P358 G359 A363 L52 M88 F89 H96 R100 I155 L238 A241 G242 T245 T246 L282 P287 L291 R294 Y317 S346 F347 G348 H352 C354 P355 G356 A360 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6d A 2.40 BS01 HEM A 1 M91 F92 H99 R103 I158 A240 L241 A244 G245 T248 L252 P290 L294 R297 Y320 S349 F350 G351 H355 C357 P358 G359 L362 A363 M88 F89 H96 R100 I155 A236 L237 A240 G241 T244 L248 P286 L290 R293 Y316 S345 F346 G347 H351 C353 P354 G355 L358 A359 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGTPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6d A 2.40 BS03 TES A 1 M84 V87 F92 F179 Q239 A240 A243 V291 L294 Q398 M81 V84 F89 F176 Q235 A236 A239 V287 L290 Q394 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGTPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4j6d B 2.40 BS02 TES B 1 M84 V87 F92 F179 F180 Q239 A240 A243 A244 V291 Q398 M81 V84 F89 F176 F177 Q235 A236 A239 A240 V287 Q394 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYADGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4jbt A 2.20 BS01 ASD A 1 M84 F179 A240 A243 A244 T248 L294 Q398 M81 F176 A237 A240 A241 T245 L291 Q395 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4jbt B 2.20 BS02 ASD B 1 M84 F92 F179 Q239 A240 A243 A244 T248 Q398 M81 F89 F176 Q236 A237 A240 A241 T245 Q395 Q5YNS8 CPHSDTLTIDPMITDLAGETSRLRAAGPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDRSMFTVDGPEHRRLRIKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKSVFAYPLPMRVISALMGVPSEDQEQLLTWYKAFFSILTPQDERLRVIDEMHGYFTEMVRRKTAEPGDDLTSALIYATDGETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFDITRATAARHISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPALPLDQIPNLPVLTQNDLSHFPIHLGR 4jcw B 1.75 BS01 CE5 B 1 L12 G21 N22 S24 D67 H70 K115 W122 Y153 L12 G21 N22 S24 D67 H70 K115 W122 Y153 3.2.1.4 A5CLK3 MTTHGRATHYSLGQGNTIANGNCSMPAVPADRMYVAVSSPEYSGAAACGTFLDVTGPKGTVRVQVADQCHGCEVGHLDLSEEAFRALGDFNAGIIPISYVTVRDPAGPTVAIRVKEGSSRWWAGLQVLNAGNRIDRVEIQAGRQWLPLTRTDYGYWVTPSPIQDGPLTVKVTDQYGRAVVLPGLRMAPGEIQRTASRFYPVH 4je2 A 1.65 BS01 F95 A 1 D443 E478 D498 S499 H539 D549 D19 E54 D74 S75 H115 D125 3.1.13.2 P03366 LWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 4je2 A 1.65 BS02 MN A 1 D443 D498 D549 D19 D74 D125 3.1.13.2 P03366 LWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 4je2 A 1.65 BS03 MN A 2 D443 E478 D498 D19 E54 D74 3.1.13.2 P03366 LWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIR 4jgd A 2.05 BS02 4JG A 1 M43 L46 P52 H56 A59 T63 L68 Y356 L359 T360 P364 M11 L14 P20 H24 A27 T31 L36 Y324 L327 T328 P332 1.3.5.2 Q02127 GDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 4jgn A 1.86 BS01 NUC E 1 S14 P15 W17 W20 N30 Q31 P34 L35 K38 Y51 Q85 I86 G87 R93 G96 S102 G103 G104 S12 P13 W15 W18 N28 Q29 P32 L33 K36 Y49 Q83 I84 G85 R91 G94 S100 G101 G102 P69517 HMTSPFKLPDESPSWTEWRLHNDETNSNQDNPLGFKESWGFGKVVFKRYLRYDRTEASLHRVLGSWTGDSVNYAASRFFGFDQIGCTYSIRFRGVSITVSGGSRTLQHLCEMAIRSKQELLQLAP 4jgu A 1.42 BS01 CA A 1 N774 K775 D802 D804 D844 N9 K10 D37 D39 D79 Q46085 AEIKDLSENKLPVIYMHVPKSGALNQKVVFYGKGTYDPDGSIAGYQWDFGDGSDFSSEQNPSHVYTKKGEYTVTLRVMDSSGQMSEKTMKIKITD 4jna A 2.00 BS01 III I 1 C177 Y179 M267 H314 R315 G316 G317 C133 Y135 M223 H270 R271 G272 G273 A4ZPY8 SPMLFDVIVIGGSHAGQSAALQIARARRRVLVIDAGARRNRFASQSHGVIGQDGRSPDAIAADGKAQLLAYPNAQWREDSVVRAERSDAGYTLICASGQHYRACQLVLAFGVVDELPELEGLEERWGESVFHCPYCHGYELDGGRIGVLGSGPLSYLSAMLMPEWGQTVFLTDASFEPDEEQREALARRGVEIVRDRIARIVDRATVELADGRRIAFDGLFTMNRMRLSSPVAEQLGCAIEEGPLGPYVRTDDAMETSTPGVFACGDITHRGGTVALAIGNGALAGIAAHRKLVFG 4jna A 2.00 BS02 FAD A 1 G55 S57 H58 A59 I77 D78 A79 G80 A81 R82 R83 N84 S90 H91 D123 S124 V125 A153 F154 G155 D158 W170 G171 C180 H181 S273 G310 D311 G317 T318 V319 G11 S13 H14 A15 I33 D34 A35 G36 A37 R38 R39 N40 S46 H47 D79 S80 V81 A109 F110 G111 D114 W126 G127 C136 H137 S229 G266 D267 G273 T274 V275 A4ZPY8 SPMLFDVIVIGGSHAGQSAALQIARARRRVLVIDAGARRNRFASQSHGVIGQDGRSPDAIAADGKAQLLAYPNAQWREDSVVRAERSDAGYTLICASGQHYRACQLVLAFGVVDELPELEGLEERWGESVFHCPYCHGYELDGGRIGVLGSGPLSYLSAMLMPEWGQTVFLTDASFEPDEEQREALARRGVEIVRDRIARIVDRATVELADGRRIAFDGLFTMNRMRLSSPVAEQLGCAIEEGPLGPYVRTDDAMETSTPGVFACGDITHRGGTVALAIGNGALAGIAAHRKLVFG 4jna B 2.00 BS01 III H 1 C177 Y179 L198 M267 P288 L289 T313 H314 R315 G316 C130 Y132 L151 M220 P241 L242 T266 H267 R268 G269 A4ZPY8 LFDVIVIGGSHAGQSAALQIARARRRVLVIDAGARRNRFASQSHGVIGQDGRSPDAIAADGKAQLLAYPNAQWREDSVVRAERSDAGYTLICASGQHYRACQLVLAFGVVDELPELEGLEERWGESVFHCPYCHGYELDGGRIGVLGSGPLSYLSAMLMPEWGQTVFLTDASFEPDEEQREALARRGVEIVRDRIARIVDRATVELADGRRIAFDGLFTMNRMRLSSPVAEQLGCAIEEGPLGPYVRTDDAMETSTPGVFACGDITHRGGTVALAIGNGALAGIAAHRKLVFG 4jp4 A 1.43 BS01 ZN A 1 H222 H226 H232 H119 H123 H129 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYHFMLPDDDVQGIQSLYGPGDED 4jp4 A 1.43 BS02 CA A 1 D162 N194 Y195 G196 D198 D59 N91 Y92 G93 D95 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYHFMLPDDDVQGIQSLYGPGDED 4jp4 A 1.43 BS03 ZN A 2 H172 D174 H187 H200 H69 D71 H84 H97 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYHFMLPDDDVQGIQSLYGPGDED 4jp4 A 1.43 BS05 AZ4 A 1 L184 L185 A186 H187 A188 L218 H222 E223 H226 H232 L239 F241 P242 I243 Y244 T245 F252 L81 L82 A83 H84 A85 L115 H119 E120 H123 H129 L136 F138 P139 I140 Y141 T142 F145 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYHFMLPDDDVQGIQSLYGPGDED 4jp4 B 1.43 BS05 AZ4 B 1 L184 L185 A186 H187 A188 L218 H222 E223 H226 H232 L239 F241 P242 I243 T245 L81 L82 A83 H84 A85 L115 H119 E120 H123 H129 L136 F138 P139 I140 T142 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 4jpa A 2.00 BS05 AZ6 A 1 L184 L185 A186 H187 L218 H222 E223 H226 H232 G237 A238 L239 F241 P242 I243 Y244 T245 Y246 F252 L81 L82 A83 H84 L115 H119 E120 H123 H129 G134 A135 L136 F138 P139 I140 Y141 T142 Y143 F145 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYHFMLPDDDVQGIQSLYGPGDED 4jpa B 2.00 BS05 AZ6 B 1 L185 A186 L218 H222 E223 H226 H232 A238 L239 F241 P242 I243 T245 Y246 T247 F252 L82 A83 L115 H119 E120 H123 H129 A135 L136 F138 P139 I140 T142 Y143 T144 F149 3.4.24.- P45452 23810497 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 4jqe A 1.77 BS01 ANP A 1 R48 G49 K50 Y51 S52 V54 V67 K69 I134 E153 V155 I213 D214 R46 G47 K48 Y49 S50 V52 V65 K67 I132 E151 V153 I211 D212 2.7.11.1 P15790 24531484 CRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4jr7 A 1.48 BS01 GNP A 1 V46 G47 R48 S52 V54 V67 K69 V155 N157 D195 K197 H199 N200 M202 I213 D214 V46 G47 R48 S49 V51 V64 K66 V150 N152 D190 K192 H194 N195 M197 I208 D209 2.7.11.1 P15790 24531484 MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRSEVFQGVKLDSKVKIVIKMLKKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK 4js0 A 1.90 BS01 III B 1 T3 I4 K5 T17 I21 Y23 V36 F37 D38 N39 Y40 A41 V42 T43 V44 M45 I46 G47 T52 G54 F56 L67 L70 S71 K166 D170 I173 L174 T3 I4 K5 T17 I21 Y23 V36 F37 D38 N39 Y40 A41 V42 T43 V44 M45 I46 G47 T52 G54 F56 L67 L70 S71 K166 D170 I173 L174 P60953 MQTIKCVVVGDVAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 4js0 A 1.90 BS02 GNP A 1 V12 A13 V14 G15 K16 T17 C18 F28 Y32 P34 T35 G60 Q116 D118 L119 S158 A159 L160 V12 A13 V14 G15 K16 T17 C18 F28 Y32 P34 T35 G60 Q116 D118 L119 S158 A159 L160 P60953 MQTIKCVVVGDVAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE 4jzx A 1.80 BS02 476 A 1 F94 D98 D102 R107 T163 T164 Q167 K207 T208 D250 K264 F94 D98 D102 R107 T163 T164 Q167 K207 T208 D250 K264 2.5.1.1,2.5.1.10 Q4QBL1 MAHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKLGKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQK 4jzx B 1.80 BS03 CA B 1 D98 D102 D170 D98 D102 D170 2.5.1.1,2.5.1.10 Q4QBL1 MAHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKLGKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQK 4kaz A 1.90 BS01 NUC B 1 E25 T26 F29 A74 F77 N78 H120 N121 F124 V163 L164 S165 K166 Q169 D174 F175 S177 H181 D186 E18 T19 F22 A67 F70 N71 H113 N114 F117 V156 L157 S158 K159 Q162 D167 F168 S170 H174 D179 3.1.13.- P30014 TGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAAE 4kb0 A 2.00 BS01 NUC C 1 V24 E25 T26 F29 E73 A74 F77 N78 H120 N121 F124 V163 L164 V18 E19 T20 F23 E67 A68 F71 N72 H114 N115 F118 V157 L158 3.1.13.- P30014 LTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAAE 4kb1 B 1.80 BS02 MG B 1 D23 E25 A180 D186 D17 E19 A174 D180 3.1.13.- P30014 LTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSA 4kvg A 1.65 BS01 GTP A 1 V12 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 G60 N116 K117 D119 L120 S147 A148 V13 G14 V15 G16 K17 S18 A19 F29 V30 E31 Y33 P35 T36 G61 N114 K115 D117 L118 S145 A146 P62834 24287201 HMREYKLVVLGSVGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR 4l61 A 2.13 BS01 MET A 1 I446 G447 S448 E499 M505 M566 D614 H657 C659 C739 G740 I437 G438 S439 E489 M495 M556 D604 H647 C649 C728 G729 2.1.1.14 P82610 24524835 MVQSSVLGFPRIGGQRELKKITEAYWSGKATVEELLAKGKELREHNWKLQQKAGVDIIPSNDFSYYDQVLDLSLLFNAIPERYTKFDLAPIDVLFAMGRGLQAAVTALEMVKWFDSNYHYVRPTFSHSTEFKLNTAAGIKPVDEFNEAKALGVQTRPVILGPVSYLYLGKADKDSLDLEPISLLPKILPVYKELLQKLKEAGAEQVQIDEPVLVLDLPEAVQSKFKEAYDALVGADVPELILTTYFGDVRPNLKAIENLPVAGFHFDFVRVPEQLDEVASILKDGQTLSAGVVDGRNIWKTDFAKASAVVQKAIEKVGKDKVVVATSSSLLHTPVDLESETKLDAVIKDWFSFATQKLDEVVVIAKNVSGEDVSKQLEANAASIKARSESSITNDPKVQERLTTINEALATRKAAFPERLTEQKAKYNLPLFPTTTIGSFPQTKDIRINRNKFAGQITAEEYEAFINKEIETVVRFQEEIGLDVLVHGEPERNDMVQYFGEQLNGFAFTTNGWVQSYGSRYVRPPIIVGDVSRPKAMTVKESVYAQSITSKPMKGMLTGPVTILRWSFPRDDVSGKIQALQLGLALRDEVNDLEGAGITVIQVDEPAIREGLPLRAGKERSDYLNWAAQSFRVATSGVENSTQIHSHFCYSDLDPNHIKALDADVVSIEFSKKDPNYIQEFSEYPNHIGLGLFDIHSPRIPSKQEFVSRIEEILKVYPASKFWVNPDCGLKTRGWPEVKESLTNMVEAAKEFRAK 4l64 A 2.18 BS02 C2F A 1 K19 W523 S526 Y527 R530 Y531 V532 W576 K19 W517 S520 Y521 R524 Y525 V526 W570 2.1.1.14 P82610 24524835 MVQSSVLGFPRIGGQRELKKITEAYWSGKATVEELLAKGKELREHNWKLQQKAGVDIIPSNDFSYYDQVLDLSLLFNAIPERYTKFDLAPIDVLFAMGRGLQAAQAAVDVTALEMVKWFDSNYHYVRPTFSHSTEFKLNTAAGIKPVDEFNEAKALGVQTRPVILGPVSYLYLGKADKDSLDLEPISLLPKILPVYKELLQKLKEAGAEQVQIDEPVLVLDLPEAVQSKFKEAYDALVGADVPELILTTYFGDVRPNLKAIENLPVAGFHFDFVRVPEQLDEVASILKDGQTLSAGVVDGRNIWKTDFAKASAVVQKAIEKVGKDKVVVATSSSLLHTPVDLESETKLDAVIKDWFSFATQKLDEVVVIAKNVSGEDVSKQLEANAASIKARSESSITNDPKVQERLTTINEALATRKAAFPERLTEQKAKYNLPLFPTTTIGSFPKDIRINRNKFAKGQITAEEYEAFINKEIETVVRFQEEIGLDVLVHGEPERNDMVQYFGEQLNGFAFTTNGWVQSYGSRYVRPPIIVGDVSRPKAMTVKESVYAQSITSKPMKGMLTGPVTILRWSFPRDDVSGKIQALQLGLALRDEVNDLEGAGITVIQVDEPAIREGLPLRAGKERSDYLNWAAQSFRVATSGVENSTQIHSHFCYDPNHIKALDADVVSIEEFSEYPNHIGLGLFPSKQEFVSRIEEILKPASKFWVNPDCGLRGWPEVKESLTNMVEAAKEFR 4l65 A 2.31 BS02 C2F A 1 K19 N126 D504 Y527 R530 Y531 V532 W576 K19 N115 D493 Y516 R519 Y520 V521 W565 2.1.1.14 P82610 24524835 MVQSSVLGFPRIGGQRELKKITEAYWSGKATVEELLAKGKELREHNWKLQQKAGVDIIPSNDFSYYDQVLDLSLLFNAIPERYTKFDLAPIDVLFAMGRGLQVTALEMVKWFDSNYHYVRPTFSHSTEFKLNTAAGIKPVDEFNEAKALGVQTRPVILGPVSYLYLGKADKDSLDLEPISLLPKILPVYKELLQKLKEAGAEQVQIDEPVLVLDLPEAVQSKFKEAYDALVGADVPELILTTYFGDVRPNLKAIENLPVAGFHFDFVRVPEQLDEVASILKDGQTLSAGVVDGRNIWKTDFAKASAVVQKAIEKVGKDKVVVATSSSLLHTPVDLESETKLDAVIKDWFSFATQKLDEVVVIAKNVSGEDVSKQLEANAASIKARSESSITNDPKVQERLTTINEALATRKAAFPERLTEQKAKYNLPLFPTTTIGSFPQTKDIRINRNKFAKGQITAEEYEAFINKEIETVVRFQEEIGLDVLVHGEPERNDMVQYFGEQLNGFAFTTNGWVQSYGSRYVRPPIIVGDVSRPKAMTVKESVYAQSITSKPMKGMLTGPVTILRWSFPRDDVSGKIQALQLGLALRDEVNDLEGAGITVIQVDEPAIREGLPLRAGKERSDYLNWAAQSFRVATSGVENSTQIHSHFCYSDLDPNHIKALDADVVSIEFSNYIQEFSEYPNHIGLGLFDIHSPRIPSKQEFVSRIEEILKYPASKFWVNPDCGLKTRGWPEVKESLTNMVEAAKEFRAKY 4l6h A 1.75 BS02 MTX A 1 K19 D504 S526 R530 Y531 V532 P535 W576 K19 D502 S524 R528 Y529 V530 P533 W574 2.1.1.14 P82610 24524835 MVQSSVLGFPRIGGQRELKKITEAYWSGKATVEELLAKGKELREHNWKLQQKAGVDIIPSNDFSYYDQVLDLSLLFNAIPERYTKFDLAPIDVLFAMGRGLQAAATQAAVDVTALEMVKWFDSNYHYVRPTFSHSTEFKLNTAAGIKPVDEFNEAKALGVQTRPVILGPVSYLYLGKADKDSLDLEPISLLPKILPVYKELLQKLKEAGAEQVQIDEPVLVLDLPEAVQSKFKEAYDALVGADVPELILTTYFGDVRPNLKAIENLPVAGFHFDFVRVPEQLDEVASILKDGQTLSAGVVDGRNIWKTDFAKASAVVQKAIEKVGKDKVVVATSSSLLHTPVDLESETKLDAVIKDWFSFATQKLDEVVVIAKNVSGEDVSKQLEANAASIKARSESSITNDPKVQERLTTINEALATRKAAFPERLTEQKAKYNLPLFPTTTIGSFPQTKDIRINRNKFAKGQITAEEYEAFINKEIETVVRFQEEIGLDVLVHGEPERNDMVQYFGEQLNGFAFTTNGWVQSYGSRYVRPPIIVGDVSRPKAMTVKESVYAQSITSKPMKGMLTGPVTILRWSFPRDDVSGKIQALQLGLALRDEVNDLEGAGITVIQVDEPAIREGLPLRAGKERSDYLNWAAQSFRVATSGVENSTQIHSHFCLDPNHIKALDADVVSIEFSKDDPNYIQEFSEYPNHIGLGLFDIHSPRIPSKQEFVSRIEEILKVYPASKFWVNPDCGLKTRGWPEVKESLTNMVEAAKEFRAKY 4lfi A 1.85 BS01 GNP A 1 G47 R48 G49 K50 Y51 S52 V54 V67 K69 V155 N157 D195 K197 H199 N200 M202 I213 D214 G46 R47 G48 K49 Y50 S51 V53 V66 K68 V154 N156 D194 K196 H198 N199 M201 I212 D213 2.7.11.1 P15790 24531484 KCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi A 1.85 BS02 MN A 1 K197 N200 D214 K196 N199 D213 2.7.11.1 P15790 24531484 KCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi A 1.85 BS03 MN A 2 Y51 D195 D214 Y50 D194 D213 2.7.11.1 P15790 24531484 KCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi A 1.85 BS04 SO4 A 1 R81 R194 N228 R80 R193 N227 2.7.11.1 P15790 24531484 KCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi A 1.85 BS06 SO4 A 3 R316 P318 W319 H320 I337 R315 P317 W318 H319 I336 2.7.11.1 P15790 24531484 KCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi A 1.85 BS07 SO4 A 4 R268 K317 R321 R267 K316 R320 2.7.11.1 P15790 24531484 KCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi B 1.85 BS02 MN B 1 Y51 D214 Y51 D214 2.7.11.1 P15790 24531484 MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lfi B 1.85 BS06 SO4 B 3 R316 P318 W319 H320 R316 P318 W319 H320 2.7.11.1 P15790 24531484 MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIE 4lmg A 2.20 BS01 NUC G 1 R54 K58 V73 I74 E75 R76 S77 D78 R87 S88 R13 K17 V32 I33 E34 R35 S36 D37 R46 S47 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLP 4lmg A 2.20 BS02 NUC H 1 R76 D78 K81 T83 R112 R114 M129 R35 D37 K40 T42 R53 R55 M70 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLP 4lmg A 2.20 BS03 ZN A 1 C86 C109 H133 H135 C45 C50 H74 H76 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLP 4lmg B 2.20 BS01 NUC E 1 K58 V73 I74 E75 R76 S77 S88 K17 V32 I33 E34 R35 S36 S47 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4lmg B 2.20 BS02 NUC F 1 R76 D78 R35 D37 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4lmg B 2.20 BS04 ZN B 2 D53 H55 D12 H14 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4lmg C 2.20 BS01 NUC E 1 R76 S80 K81 Y117 V119 R120 W124 R35 S39 K40 Y58 V60 R61 W65 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4lmg C 2.20 BS02 NUC F 1 R54 K58 V73 I74 E75 R76 S77 D78 S88 R13 K17 V32 I33 E34 R35 S36 D37 S47 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSVACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4lmg D 2.20 BS01 NUC G 1 R76 S79 S80 K81 Y117 S118 V119 R120 R35 S38 S39 K40 Y57 S58 V59 R60 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4lmg D 2.20 BS02 NUC H 1 H55 K58 V73 I74 E75 R76 S77 D78 R87 S88 H14 K17 V32 I33 E34 R35 S36 D37 R46 S47 Q08957 LIHLDPVPSFEDRHEIKPWLQKIFYPQGIDIVIERSDSSKVTFKCRSACPFRIRAAYSVRLQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL 4m32 A 1.86 BS03 FE2 B 2 K38 H41 W42 K37 H40 W41 A0QXB7 SARRTESDIQGFHATPEFGGNLQKVLVDLIELSLQGKQAHWNVVGSNFRDLHLQLDELVDFAREGSDTIAERMRALDAVPDGRSDTVAATTTLPEFPAFERSTADVVDLITTRINATVDTIRRVHDAVDAEDPSTANLLHGLIDGLEKQAWLIRSENRKV 4m33 A 2.22 BS03 FE2 B 1 H41 D57 H41 D57 A0QXB7 MSARRTESDIQGFHATPEFGGNLQKVLVDLIELSLQGKQAHWNVVGSNFRDLHLQLDELVDFAREGSDTIAERMRALDAVPDGRSDTVAATTTLPEFPAFERSTADVVDLITTRINATVDTIRRVHDAVDAEDPSTADLLDGLIDGLEKQAWLIRSENRKV 4m6u A 1.80 BS02 TTN A 1 K164 K166 D195 N197 E221 E247 H297 E317 L319 K162 K164 D193 N195 E219 E245 H295 E315 L317 5.1.2.2 P11444 24472022 EVLITGLRTRAVNVPLAYPVHTAVGTVGTAPLVLIDLATSAGVVGHSYLFAYTPVALKSLKQLLDDMAAMIVNEPLAPVSLEAMLAKRFCLAGYTGLIRMAAAGIDMAAWDALGKVHETPLVKLLGANARPVQAYDSHSLDGVKLATERAVTAAELGFRAVKTKIGYPALDQDLAVVRSIRQAVGDDFGIMVDYNQSLDVPAAIKRSQALQQEGVTWIEEPTLQHDYEGHQRIQSKLNVPVQMGENWLGPEEMFKALSIGACRLAMPDAMKIGGVTGWIRASALAQQFGIPMSSHLFQEISAHLLAATPTAHWLERLDLAGSVIEPTLTFEGGNAVIPDLPGVGIIWREKEIGKYLV 4m6u B 1.80 BS02 TTN B 1 K164 K166 D195 N197 E221 E247 H297 E317 K162 K164 D193 N195 E219 E245 H295 E315 5.1.2.2 P11444 24472022 EVLITGLRTRAVNVPLAYPVHTAVGTVGTAPLVLIDLATSAGVVGHSYLFAYTPVALKSLKQLLDDMAAMIVNEPLAPVSLEAMLAKRFCLAGYTGLIRMAAAGIDMAAWDALGKVHETPLVKLLGANARPVQAYDSHSLDGVKLATERAVTAAELGFRAVKTKIGYPALDQDLAVVRSIRQAVGDDFGIMVDYNQSLDVPAAIKRSQALQQEGVTWIEEPTLQHDYEGHQRIQSKLNVPVQMGENWLGPEEMFKALSIGACRLAMPDAMKIGGVTGWIRASALAQQFGIPMSSHLFQEISAHLLAATPTAHWLERLDLAGSVIEPTLTFEGGNAVIPDLPGVGIIWREKEIGKYLV 4m7u A 2.10 BS01 NAP A 1 W6 A7 I14 G15 G18 K19 L20 G43 R44 A45 T46 L63 T64 S65 H78 S79 V80 G97 G98 G99 S100 V101 V102 F103 E105 T126 W14 A15 I22 G23 G26 K27 L28 G51 R52 A53 T54 L71 T72 S73 H86 S87 V88 G105 G106 G107 S108 V109 V110 F111 E113 T134 1.5.1.3 Q834R2 24495113 MENLYFQGMLAAIWAQDEQGVIGKEGKLPWHLPNDLKFFKEKTIHNTLVLGRATFEGMGCRPLPNRTTIVLTSNPDYQAEGVLVMHSVEEILAYADKYEGVTVIGGGSVVFKELIPACDVLYRTMIHETFEGDTFFPEIDWSVWEKVATVPGVVDEKNLYAHDYETYHRN 4m7v A 2.30 BS01 RAR A 1 I5 W6 A7 G18 L20 D27 L28 F31 K32 L55 R58 G97 I10 W11 A12 G23 L25 D32 L33 F36 K37 L60 R63 G102 1.5.1.3 Q834R2 24495113 LYFQGMLAAIWAQDEQGVIGKEGKLPWHLPNDLKFFKEKTIHNTLVLGRATFEGMGCRPLPNRTTIVLTSNPDYQAEGVLVMHSVEEILAYADKYEGVTVIGGGSVVFKELIPACDVLYRTMIHETFEGDTFFPEIDWSVWEKVATVPGVVDEKNLYAHDYETYHRND 4mf9 A 1.95 BS01 HEM A 1 L103 R112 F114 T208 H209 R222 M257 F259 K307 Q329 F331 R334 P336 L95 R104 F106 T200 H201 R214 M249 F251 K299 Q321 F323 R326 P328 O68880 24560694 HSPAELYRAWQDLRAERPQLRARDAAALLQVSEGELVASRVGIDAVRLRPDWAALLPALGELGPIMALTRNEHCVHERKGPYREVTVSANGQMGLVVSPDIDLRLFLGGWNAVFAIAEETARGTQRSIQVFDQQGVAVHKVFLAEASDVRAWEPLVERLRAAEQDAVLALHEPRAPAAALVDAQIDAAALREGWAALKDTHHFHALLKKHGAQRTQALRLAGGEWAERLDNGDLAKLFEAAAESGLPIMVFVGNAHCIQIHTGPVCNLKWLDDWFNVLDPEFNLHLKTTGIAELWRVRKPSTDGIVTSWEAFDPDGELIVQLFGARKPGEPERDDWRELAESFKAL 4mnt A 1.58 BS01 CU A 1 E18 C106 E17 C105 3.4.-.- Q99497 ASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLK 4mp6 A 2.10 BS01 NAD A 1 R94 R122 T123 I145 G146 G148 L149 I150 Y171 D172 Q173 C213 T214 V215 I235 P306 G308 R92 R120 T121 I143 G144 G146 L147 I148 Y169 D170 Q171 C211 T212 V213 I233 P304 G306 Q8NYS7 24485762 REMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 4mp6 A 2.10 BS02 CIT A 1 R60 I62 M64 K78 R94 R122 G308 R58 I60 M62 K76 R92 R120 G306 Q8NYS7 24485762 REMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 4mp8 A 1.85 BS01 NAD A 1 R60 R94 R122 T123 G148 L149 I150 Y171 D172 Q173 C213 T214 V215 I235 P306 G308 R58 R92 R120 T121 G146 L147 I148 Y169 D170 Q171 C211 T212 V213 I233 P304 G306 Q8NYS7 24485762 REMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 4mp8 A 1.85 BS02 MLI A 1 R60 I80 R94 A95 R58 I78 R92 A93 Q8NYS7 24485762 REMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 4mpd A 2.10 BS01 NAJ A 1 R60 R94 R122 T123 G148 L149 I150 D172 Q173 F174 C213 T214 V215 T216 I235 P306 G308 R51 R80 R108 T109 G134 L135 I136 D158 Q159 F160 C199 T200 V201 T202 I221 P288 G290 Q8NYS7 24485762 REMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQADRIIAMPSHIISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 4mpd A 2.10 BS02 AKG A 1 K45 R60 I62 M64 K78 I80 R94 A95 R122 M307 G308 K43 R51 I53 M55 K64 I66 R80 A81 R108 M289 G290 Q8NYS7 24485762 REMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPLKPYLRQADRIIAMPSHIISGIKWIGSKHDNPSKRNMERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLEQFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNTINQLVLEGKFSKEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLNLY 4mqn A 1.80 BS01 2B0 A 1 W65 G124 S125 Y157 H158 E220 D254 I256 A257 K283 W57 G116 S117 Y149 H150 E212 D246 I248 A249 K275 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqn A 1.80 BS02 KAP A 1 Y25 W64 Y157 A226 K283 R400 F402 Y18 W56 Y149 A218 K275 R392 F394 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqn A 1.80 BS04 KAP B 1 G316 T318 G308 T310 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqn B 1.80 BS04 KAP B 1 Y25 W64 W65 Y157 A226 K283 R400 F402 Y18 W55 W56 Y148 A217 K274 R391 F393 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGRESPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqo A 1.70 BS01 2BG A 1 Y25 W64 W65 Y157 M174 A226 F402 Y18 W54 W55 Y147 M164 A216 F392 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGRSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqo A 1.70 BS02 2B0 A 1 G124 S125 Y157 H158 E220 D254 I256 A257 K283 G114 S115 Y147 H148 E210 D244 I246 A247 K273 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGRSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqo B 1.70 BS02 2B0 A 1 G316 P317 T318 G310 P311 T312 2.6.1.62 P0A4X6 24482078 GLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLV 4mqp A 1.83 BS01 2B1 A 1 W64 W65 G124 S125 Y157 H158 G159 E220 G225 A226 M229 D254 I256 K283 Y407 W57 W58 G117 S118 Y150 H151 G152 E213 G218 A219 M222 D247 I249 K276 Y400 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqp B 1.83 BS02 2B1 B 1 W64 W65 G124 S125 Y157 H158 G159 E220 A226 D254 I256 K283 F402 Y407 W57 W58 G117 S118 Y150 H151 G152 E213 A219 D247 I249 K276 F395 Y400 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG 4mqq A 1.70 BS01 2B6 A 1 Y25 W64 W65 G124 S125 Y157 H158 G159 D254 I256 K283 Y18 W57 W58 G117 S118 Y150 H151 G152 D247 I249 K276 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqq B 1.70 BS02 2B6 B 1 P24 W64 G124 S125 Y157 H158 G159 D254 I256 K283 P18 W58 G118 S119 Y151 H152 G153 D248 I250 K277 2.6.1.62 P0A4X6 24482078 GLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG 4mqr A 2.10 BS01 2B9 A 1 Y25 W64 G124 S125 Y157 H158 G159 D254 I256 K283 Y18 W57 G117 S118 Y150 H151 G152 D247 I249 K276 2.6.1.62 P0A4X6 24482078 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4n4g A 1.95 BS01 ZN A 1 C258 C261 C277 H281 C101 C104 C120 H124 Q8R5C8 NKQEMGTYLRFIVSRMKERAIDGKDSKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWKSK 4n4h A 2.30 BS01 III B 1 E254 S265 N266 R268 M288 K289 G290 F291 W294 R309 F310 H315 Q316 R317 E78 S89 N90 R92 M112 K113 G114 F115 W118 R133 F134 H139 Q140 R141 Q8R5C8 QEMGTYLRFIVSRMKERAIDLVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGAASAQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWK 4n4i A 2.00 BS01 III B 1 R168 H250 E251 E254 F262 S265 N266 R268 M288 K289 F291 W294 R309 F310 H315 Q316 R317 R15 H78 E79 E82 F90 S93 N94 R96 M116 K117 F119 W122 R137 F138 H143 Q144 R145 Q8R5C8 NKQEMGTYLRFIVSRMKERAIDLVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGAASAQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHRLHVKRSMGWKKACDELELHQRFLREGRFWK 4nb4 A 2.25 BS01 ADP A 1 G8 G9 T10 L11 K13 L28 G98 T99 G121 G122 Q125 Y137 G224 S225 S226 G8 G9 T10 L11 K13 L28 G98 T99 G121 G122 Q125 Y137 G222 S223 S224 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK 4nb4 A 2.25 BS02 SH3 A 1 G9 E70 F71 T99 G100 T101 S102 R113 G116 I117 G9 E70 F71 T99 G100 T101 S102 R113 G116 I117 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK 4nb4 A 2.25 BS03 SH3 A 2 V156 I159 I167 L171 T172 A173 E202 Y240 V156 I159 I167 L171 T172 A173 E200 Y238 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK 4nb4 B 2.25 BS01 SH3 A 1 V156 L171 T172 A173 E202 T206 Y240 V156 L170 T171 A172 E201 T205 Y239 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLE 4nb4 B 2.25 BS02 SH3 A 3 G9 E70 F71 T99 G100 T101 S102 R113 G116 G9 E70 F71 T99 G100 T101 S102 R113 G116 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLE 4nb4 C 2.25 BS03 SH3 C 2 V156 I159 T172 A173 E202 T206 Y240 V157 I160 T171 A172 E200 T204 Y238 2.7.1.33 Q6G7I0 24470271 GMKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKEPPIPGDLTAANFGHVLHHLDDFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK 4nb4 D 2.25 BS01 SH3 C 1 V156 I159 L171 T172 A173 E202 T206 Y240 V156 I159 L171 T172 A173 E202 T206 Y240 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYL 4nb4 E 2.25 BS01 ADP E 1 G8 G9 T10 L11 K13 G98 T99 G121 G122 Q125 Y137 S225 S226 G8 G9 T10 L11 K13 G97 T98 G120 G121 Q124 Y136 S218 S219 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENIIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLE 4nb4 E 2.25 BS03 SH3 F 2 T172 A173 E202 T206 Y240 T165 A166 E195 T199 Y233 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENIIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLE 4nb4 F 2.25 BS01 ADP F 1 G8 G9 T10 L11 K13 G98 T99 G121 G122 Q125 Y137 G224 S225 H228 G8 G9 T10 L11 K13 G95 T96 G118 G119 Q122 Y134 G221 S222 H225 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYL 4nb4 F 2.25 BS03 SH3 F 3 G9 E70 T99 G100 T101 S102 R113 G116 I117 G9 E67 T96 G97 T98 S99 R110 G113 I114 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYL 4nb4 F 2.25 BS04 MG F 1 D6 E70 D6 E67 2.7.1.33 Q6G7I0 24470271 MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYL 4nb4 H 2.25 BS03 SH3 H 1 G9 E70 T99 G100 T101 S102 R113 G116 G10 E71 T100 G101 T102 S103 R114 G117 2.7.1.33 Q6G7I0 24470271 GMKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLE 4ncj A 2.00 BS01 ADP A 1 R12 S13 G33 S34 G35 K36 S37 S38 E60 F61 T62 K63 V64 R12 S13 G33 S34 G35 K36 S37 S38 E60 F61 T62 K63 V64 P58301 24493214 MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLLDAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGTKYRITRRFLKGYSSGEIHAMKRLVGNEWKHVTEPSSKAISAFMEKLIPYNIFLNAIYIRQGQIDAILESDEAREKVVREVLNLKYKALAREAALSKIGELASEIFAEFTEGKYSEVVVRAEENKVRLFVVWEGKERPLTFLSGGERIALGLAFELAMSLYLAGEISLLILDEPTPYLDEERRRKLITIMERYLKKIPQVILVSHDEELKDAADHVIRISLENGSSKVEVVS 4ncj A 2.00 BS02 BEF A 1 N32 G33 K36 Q140 N32 G33 K36 Q140 P58301 24493214 MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLLDAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGTKYRITRRFLKGYSSGEIHAMKRLVGNEWKHVTEPSSKAISAFMEKLIPYNIFLNAIYIRQGQIDAILESDEAREKVVREVLNLKYKALAREAALSKIGELASEIFAEFTEGKYSEVVVRAEENKVRLFVVWEGKERPLTFLSGGERIALGLAFELAMSLYLAGEISLLILDEPTPYLDEERRRKLITIMERYLKKIPQVILVSHDEELKDAADHVIRISLENGSSKVEVVS 4ncj B 2.00 BS01 ADP B 1 R12 S13 N32 G33 S34 G35 K36 S37 S38 E60 F61 T62 K63 V64 R12 S13 N32 G33 S34 G35 K36 S37 S38 E60 F61 T62 K63 V64 P58301 24493214 MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLLDAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGTKYRITRRFLKGYSSGEIHAMKRLVGNEWKHVTEPSSKAISAFMEKLIPYNIFLNAIYIRQGQIDAILESDEAREKVVREVLNLDYKALAREAALSKIGELASEIFAEFTEGKYSEVVVRAEENKVRLFVVWEGKERPLTFLSGGERIALGLAFELAMSLYLAGEISLLILDEPTPYLDEERRRKLITIMERYLKKIPQVILVSHDEELKDAADHVIRISLENGSSKVEVVS 4ngb A 2.25 BS01 NUC B 1 Y926 R927 F950 P951 S952 F958 Y961 Y962 K965 Y966 S1006 W1014 L1017 Q1018 Q1021 I1022 L1023 Y160 R161 F184 P185 S186 F192 Y195 Y196 K199 Y200 S229 W237 L240 Q241 Q244 I245 L246 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKPALAYCVLPLNVVSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngd A 1.96 BS01 NUC B 1 Y926 R927 F950 P951 S952 F958 Y961 Y962 K965 Y966 S1005 S1006 W1014 L1017 Q1018 K1020 Q1021 I1022 L1023 Y160 R161 F184 P185 S186 F192 Y195 Y196 K199 Y200 S232 S233 W241 L244 Q245 K247 Q248 I249 L250 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKPALAYCVLPLNVVSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngf A 3.10 BS01 NUC G 1 Q931 H933 H982 S984 K1011 W1014 Q147 H149 H198 S200 K218 W221 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRYCVLPLNVVSTLDIDFKFMEDIEKSETKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngf A 3.10 BS02 NUC H 1 Y926 R927 F950 P951 S952 F958 Y961 Y962 K965 Y966 S1005 S1006 R1010 W1014 L1017 Q1018 Q1021 I1022 L1023 Y142 R143 F166 P167 S168 F174 Y177 Y178 K181 Y182 S212 S213 R217 W221 L224 Q225 Q228 I229 L230 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRYCVLPLNVVSTLDIDFKFMEDIEKSETKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngf B 3.10 BS02 NUC F 1 H933 S984 K1011 W1014 H150 S201 K217 W220 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLYCVLPLNVSTLDIDFKFMEDIEKSEYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngf C 3.10 BS02 NUC F 1 Y926 R927 F950 P951 S952 F958 Y961 Y962 K965 Y966 A1007 R1010 W1014 L1017 Q1018 Q1021 I1022 L1023 Y141 R142 F165 P166 S167 F173 Y176 Y177 K180 Y181 A212 R215 W219 L222 Q223 Q226 I227 L228 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLYCVLPLNVVTLDIDFKFMEDIEKSEKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngf D 3.10 BS02 NUC H 1 D930 H933 S984 K1011 W1014 D147 H150 S201 K218 W221 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRYCVLPLNVSTLDIDFKFMEDIEKSEKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngg A 2.60 BS01 NUC B 1 Y926 R927 H933 F950 S952 F958 Y961 Y962 K965 Y966 W1014 Q1021 I1022 Y156 R157 H163 F180 S182 F188 Y191 Y192 K195 Y196 W228 Q235 I236 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEYCVLPLNVVNDSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4ngg A 2.60 BS02 PO4 A 1 R778 R811 H982 S984 R986 R23 R56 H212 S214 R216 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEYCVLPLNVVNDSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4nh5 A 2.55 BS01 NUC B 1 Y926 R927 F950 P951 S952 Y961 Y962 K965 Y966 W1014 L1017 Q1018 Q1021 I1022 L1023 Y156 R157 F180 P181 S182 Y191 Y192 K195 Y196 W232 L235 Q236 Q239 I240 L241 3.1.26.- Q9UPY3 24486018 QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKYCVLPLNVVNSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4nha A 3.40 BS01 NUC B 1 Y926 R927 F950 P951 S952 F958 Y961 Y962 Y966 K1020 Q1021 I1022 Y134 R135 F158 P159 S160 F166 Y169 Y170 Y174 K201 Q202 I203 3.1.26.- Q9UPY3 24486018 LYVIGMVLTTPLPDELRKLYPPEDTTRCFGILTAKPIPQIPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLSAYCVLPLNVTLDIDFKFMEDIEKSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC 4nhf B 2.00 BS01 CA B 1 D113 D115 D22 D24 C6AAT5 SYGEVVDRYWLNQYVLNRENYDYDTIQLNYDTTALLSAASVQQEYYKIYDGENARDKVLSNKARITVKVRSIQLNGLGQATVRFTTQQLDSTTGPKQHQIATIGYTYVGAPMKSSDRLLNPLGFQITSYRSDPEILLN 4niq A 2.30 BS01 III C 1 G4 L7 T8 I11 Q15 I18 D21 T22 Y46 E47 K48 N49 S52 L55 K59 E62 Y63 R66 G4 L7 T8 I11 Q15 I18 D21 T22 Y46 E47 K48 N49 S52 L55 K59 E62 Y63 R66 P52917 MSTGDFLTKGIELVQKAIDLDTATQYEEAYTAYYNGLDYLMLALKYEKNPKSKDLIRAKFTEYLNRAEQLKKHLESEEANAA 4niq B 2.30 BS01 III D 1 G4 L7 T8 I11 Q15 I18 D21 T22 Y33 K45 Y46 E47 K48 N49 K51 S52 L55 I56 K59 E62 Y63 R66 G1 L4 T5 I8 Q12 I15 D18 T19 Y30 K42 Y43 E44 K45 N46 K48 S49 L52 I53 K56 E59 Y60 R63 P52917 GDFLTKGIELVQKAIDLDTATQYEEAYTAYYNGLDYLMLALKYEKNPKSKDLIRAKFTEYLNRAEQLKKHLESEEANA 4nsq A 2.31 BS01 COA A 1 Q525 L526 C574 A575 V576 Q581 V582 K583 G584 Y585 G586 T587 Y612 A613 G615 Y616 F617 K619 Q30 L31 C79 A80 V81 Q86 V87 K88 G89 Y90 G91 T92 Y117 A118 G120 Y121 F122 K124 2.3.1.48 Q92831 24423233 KVIEFHVVGNSPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNP 4ntc A 1.90 BS01 FAD A 1 G20 A21 G22 P23 A24 D43 S44 G45 V46 Y47 R48 N49 T52 M55 H56 V58 S89 T90 I91 A121 T122 G123 D126 A139 H144 C148 F261 G293 D294 K300 A301 V302 G20 A21 G22 P23 A24 D43 S44 G45 V46 Y47 R48 N49 T52 M55 H56 V58 S89 T90 I91 A121 T122 G123 D126 A139 H144 C148 F261 G293 D294 K300 A301 V302 Q5MBU7 24446392 MSIGKLLSNGALLVDVLIIGAGPAGLSTATGLARQLHTAVVFDSGVYRNAKTQHMHNVLGWDHRNPAELRAAGRADLTTRYSTIQFQNSTIEAIRQVETNQLFEARDNEGHSWYGRKVVLATGVRDIPLDIEGYSECWANGIYHCLFCDGYEERGQETVGVLALGPIANPARALHLARMALRLSESVTIYTNGNEQLAKEIQQAAEESPVGASGLKFEARPIRRFEKGDVAKTVIVHLGESESKTEGFLVYNPQTEVNGPFAKQLALNMTEGGDILTTPPFYETSVPGVFAVGDCATPLKAVTPAVSMGSLAAGGLVAQLQAQAL 4ntd A 1.60 BS01 GSH A 1 R43 H139 C140 P141 Y142 H165 L168 P279 R280 A281 R43 H139 C140 P141 Y142 H165 L168 P279 R280 A281 E2PZ87 24446392 NGFTHEGGIDVVVIGAGAGGLNAALVLARARRRVVLVDSGAPRNAPSAHMQGFLSRDGMAPSALLETGRAEVSGYGAEFIRGEVDDVEREGEDDAPRFTVRLVGGVALSTRRVVVATGLRDELPDIPGVRERWGKDLLHCPYCHGYEVSDQPLGVLGTSPGAVRHALLLRQWSDDVVLFRHGLELTDDDRRALSARQVPVIEGTVKRLVVEDDRLRGVELAEDSGVARSTVFVVPRMVPRDGLLTALGCERGADGWIATDRSGLTSVPGVWAVGNVVDPRALVVSSAGMGSAAAFALNHQLVDEDVASAVRAAARTVA 4ntd A 1.60 BS02 FAD A 1 I14 G15 G17 A18 G19 V37 D38 S39 G40 A41 R43 N44 S47 M50 Q51 G82 E83 V84 A116 T117 D121 W133 C143 H144 R240 G274 N275 A281 L282 V283 S286 I14 G15 G17 A18 G19 V37 D38 S39 G40 A41 R43 N44 S47 M50 Q51 G82 E83 V84 A116 T117 D121 W133 C143 H144 R240 G274 N275 A281 L282 V283 S286 E2PZ87 24446392 NGFTHEGGIDVVVIGAGAGGLNAALVLARARRRVVLVDSGAPRNAPSAHMQGFLSRDGMAPSALLETGRAEVSGYGAEFIRGEVDDVEREGEDDAPRFTVRLVGGVALSTRRVVVATGLRDELPDIPGVRERWGKDLLHCPYCHGYEVSDQPLGVLGTSPGAVRHALLLRQWSDDVVLFRHGLELTDDDRRALSARQVPVIEGTVKRLVVEDDRLRGVELAEDSGVARSTVFVVPRMVPRDGLLTALGCERGADGWIATDRSGLTSVPGVWAVGNVVDPRALVVSSAGMGSAAAFALNHQLVDEDVASAVRAAARTVA 4nte A 1.90 BS01 FAD A 1 I11 G12 S14 H15 A16 I34 D35 A36 G37 A38 R40 N41 S47 H48 D80 S81 V82 F111 D115 W127 G128 C137 H138 S230 G267 D268 G274 T275 V276 I8 G9 S11 H12 A13 I31 D32 A33 G34 A35 R37 N38 S44 H45 D77 S78 V79 F106 D110 W122 G123 C132 H133 S225 G262 D263 G269 T270 V271 A4ZPY8 24446392 MLFDVIVIGGSHAGQSAALQIARARRRVLVIDAGARRNRFASQSHGVIGQDGRSPDAIAADGKAQLLAYPNAQWREDSVVRAERSGYTLICASGQHYRACQLVLAFGVVDELPELEGLEERWGESVFHCPYCHGYELDGGRIGVLGSGPLSYLSAMLMPEWGQTVFLTDASFEPDEEQREALARRGVEIVRDRIARIVDRATVELADGRRIAFDGLFTMNRMRLSSPVAEQLGCAIEEGPLGPYVRTDDAMETSTPGVFACGDITHRGGTVALAIGNGALAGIAAHRKLVFG 4nus A 2.39 BS01 2NK A 1 Q76 F79 V82 A98 K100 V131 D148 L150 L200 T210 D211 F212 Q24 F27 V30 A46 K48 V79 D96 L98 L148 T158 D159 F160 2.7.11.1 P51812 24554780 THHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATFYFDP 4o1j A 2.69 BS01 ZN A 1 C45 H101 C104 C42 H98 C101 4.2.1.1 C1L335 24506675 ENTFHYALSSNNAWAGYKAHQNPHFFPKLAGGQAPEILWIGCSDSRCPETTILGMQPGDVFVHRNIANIVSPTDINTTAVIEYAVAHLKVKHIVLCGHSACGGAAGALSDGRIGGVLDTWLLPLKTVRYNHAEELDAITDEKERVIRIAQLNVEAGIKVLMNNPTIREAIAERGLEVHGVFFDIGCGRIKELGCGTA 4o1k A 1.83 BS01 ZN A 1 C56 D58 H112 C115 C43 D45 H99 C102 4.2.1.1 C1L336 24506675 LQETHDKVFENNKSWATEQVAKDPDFFKKLAAGQNPEYLWIGCSDSRIPAEQITGLQPGDAFVHRNIANLVCNTDLNVMSVIEYAVKHLKVKHIVVCGHYGCGGVKAAMTPKDLGLMNPWLRNIRDVYRLHEKELDAIADEEARYERLVELNVYEQCRNVVKTAALQQSYAENGFPVIHGWVFNFRDGLLKDLNVDFETILKDIQKIYNLT 4o2a A 2.50 BS01 GTP A 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 V177 S178 T179 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 V177 S178 T179 E183 N206 Y224 N228 I231 P81947 24530796 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVEE 4o2a A 2.50 BS02 CA A 1 D39 T41 G44 F49 E55 D39 T41 G44 F49 E55 P81947 24530796 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVEE 4o2a B 2.50 BS01 GDP B 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 V177 D179 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 V175 D177 E181 N204 Y222 N226 Q6B856 24530796 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4o2a B 2.50 BS02 2RR B 1 Y202 V238 C241 L248 A250 L255 N258 M259 V315 A316 I318 N349 N350 K352 I378 Y200 V236 C239 L246 A248 L253 N256 M257 V303 A304 I306 N337 N338 K340 I358 Q6B856 24530796 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLLTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4o2a C 2.50 BS01 GTP C 1 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 S178 E183 N206 Y224 N228 I231 G10 Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 G146 I171 S178 E183 N206 Y224 N228 I231 P81947 24530796 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4o2a C 2.50 BS02 CA C 1 D39 T41 G44 D47 E55 D39 T41 G44 D47 E55 P81947 24530796 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4o2a F 2.50 BS01 ADP F 1 K74 K150 Q183 K184 Y185 L186 K198 L240 T241 M320 I330 E331 K74 K127 Q143 K144 Y145 L146 K158 L200 T201 M280 I290 E291 E1BQ43 24530796 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPDEREVFLAAYNRRREGREGNVWIAKSISSEASELLDFHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLAPTSIFIKLH 4o2b B 2.30 BS02 LOC B 1 C241 L242 L248 A250 D251 K254 L255 N258 M259 T314 V315 A316 I318 N350 K352 I378 C239 L240 L246 A248 D249 K252 L253 N256 M257 T306 V307 A308 I310 N342 K344 I362 Q6B856 24530796 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDA 4o2b C 2.30 BS02 CA C 1 E279 Y282 E279 Y282 P81947 24530796 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4o2b C 2.30 BS03 LOC D 1 S178 A180 V181 S178 A180 V181 P81947 24530796 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSV 4o2b F 2.30 BS01 MG F 1 R222 D318 R177 D269 E1BQ43 24530796 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNGNVWIAKSISSEASELLDFIHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKEYSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 4o2b F 2.30 BS02 ACP F 1 K74 K150 Q183 K184 Y185 L186 K198 D200 H239 L240 T241 N242 D318 I330 E331 N333 K74 K121 Q138 K139 Y140 L141 K153 D155 H191 L192 T193 N194 D269 I281 E282 N284 E1BQ43 24530796 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTDEREVFLAAYNGNVWIAKSISSEASELLDFIHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSADKTCHLTNHCIQKEYSNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLASIFIKL 4o4h B 2.10 BS02 LLM B 1 Q293 F296 D297 S298 P307 R308 N334 V335 N339 Y342 Q287 F290 D291 S292 P301 R302 N328 V329 N333 Y336 Q6B856 24470331 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA 4o4h D 2.10 BS01 GDP D 1 G10 Q11 C12 Q15 S140 G143 G144 T145 G146 P173 E183 N206 Y224 N228 G10 Q11 C12 Q15 S138 G141 G142 T143 G144 P171 E181 N204 Y222 N226 Q6B856 24470331 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAD 4o4h F 2.10 BS01 ACP F 1 K74 K150 Q183 K184 Y185 L186 K198 R202 R222 L240 T241 N242 D318 I330 E331 N333 K74 K131 Q159 K160 Y161 L162 K174 R178 R198 L216 T217 N218 D294 I306 E307 N309 E1BQ43 24470331 MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTNLTDEREVFLAAYNRRREGREGNVWIAKSSEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLAPTSIFIKLHH 4o70 A 1.55 BS01 1QK A 1 W81 P82 F83 V87 L92 L94 Y139 N140 D144 D145 I146 W40 P41 F42 V46 L51 L53 Y98 N99 D103 D104 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o70 A 1.55 BS02 1QK A 2 V90 K91 L92 N93 V49 K50 L51 N52 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o71 A 1.36 BS01 CPB A 1 W81 P82 Q85 V87 L92 L94 Y97 Y139 N140 I146 W40 P41 Q44 V46 L51 L53 Y56 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o71 B 1.36 BS01 CPB B 1 W81 P82 V87 L92 Y97 Y139 N140 I146 W40 P41 V46 L51 Y56 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o72 A 1.40 BS01 2R4 A 1 W81 P82 F83 Q85 P86 V87 D88 L92 L94 Y139 N140 I146 W40 P41 F42 Q44 P45 V46 D47 L51 L53 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o75 A 1.55 BS01 2RC A 1 W81 P82 F83 Q85 V87 K91 L92 L94 Y97 Y139 N140 W40 P41 F42 Q44 V46 K50 L51 L53 Y56 Y98 N99 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o76 B 1.70 BS01 1M3 B 1 P82 F83 V87 L92 L94 N140 I146 P41 F42 V46 L51 L53 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o77 A 2.00 BS01 2RE A 1 W81 P82 V87 L92 Y97 N135 C136 N140 I146 W40 P41 V46 L51 Y56 N94 C95 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o77 B 2.00 BS01 2RE B 1 W81 P82 V87 L92 Y97 N135 C136 N140 W40 P41 V46 L51 Y56 N94 C95 N99 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o78 A 1.34 BS01 SAV A 1 W81 P82 F83 Q85 V87 L92 L94 Y97 C136 Y139 D145 I146 W40 P41 F42 Q44 V46 L51 L53 Y56 C95 Y98 D104 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7a A 1.34 BS01 2RF A 1 W81 P82 Q85 V87 L92 L94 N140 I146 M149 W40 P41 Q44 V46 L51 L53 N99 I105 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7b A 1.50 BS01 2RJ A 1 W81 P82 F83 V87 L92 L94 Y97 M132 N140 D145 I146 W40 P41 F42 V46 L51 L53 Y56 M91 N99 D104 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7c A 1.55 BS01 2RK A 1 W81 P82 F83 Q85 V87 L92 Y139 N140 I146 W40 P41 F42 Q44 V46 L51 Y98 N99 I105 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7e A 1.85 BS01 2RN A 1 W81 P82 V87 L92 W40 P41 V46 L51 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7e A 1.85 BS02 2RN A 2 Q78 F79 D145 L148 M149 Q37 F38 D104 L107 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7e B 1.85 BS01 2RN B 1 Q78 F79 W81 D145 M149 Q37 F38 W40 D104 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7e B 1.85 BS02 2RN B 2 W81 P82 Q85 V87 L92 W40 P41 Q44 V46 L51 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7f A 1.80 BS01 2RQ A 1 W81 P82 F83 V87 L92 L94 Y97 C136 N140 I146 M149 W40 P41 F42 V46 L51 L53 Y56 C95 N99 I105 M108 O60885 SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 4o7m A 1.50 BS01 LMR A 1 V41 V42 K48 S98 K101 R176 M178 F199 N216 N220 L241 Y243 V9 V10 K16 S66 K69 R144 M146 F167 N184 N188 L209 Y211 A3QCW5 PTEIKFSHVVAENTPKGQMALKFKQLVEERLPGEYQVNVFPNSQLFGDNNELSALLLNDVQFVAPSLSKFERYTKKLQLFDLPFLFKDMDAVNRFQQSDAGQQLLNSMKRKGVVGLGYLHNGMKQFSASSPLVLPEDAQGKKFRIMASDVLAAQFQAVEAIPVKKPFSEVFTLLQTRAIDGQENTWSNIYSKKFYEVQSNITESNHGVLDYMVVTSNTFWKSLPADKRKVIKASLDEAIAYGNEIAAAKVNKDKQAIIDSKRSEVTYLTPEQRAAWVNAMKPVWAQFEDKIGKDLIDAAVASNE 4o9r A 3.20 BS01 CY8 A 1 N219 F222 L303 D384 V386 Y394 R400 D473 Q477 E481 F484 E518 N28 F31 L112 D183 V185 Y193 R199 D371 Q375 E379 F382 E408 Q99835 24525480 QCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCR 4oa5 A 2.30 BS01 SAH A 1 Q39 L40 G64 T65 C66 F69 S70 E88 K89 N93 G115 E116 A117 D136 A137 N138 Q33 L34 G58 T59 C60 F63 S64 E82 K83 N87 G109 E110 A111 D130 A131 N132 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 A 2.30 BS02 IOD A 1 L166 F167 S180 A183 L160 F161 S174 A177 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 A 2.30 BS03 IOD A 2 Q49 R53 H76 A77 Q43 R47 H70 A71 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 A 2.30 BS04 IOD A 3 S59 Y85 F130 S53 Y79 F124 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 A 2.30 BS05 IOD A 4 K139 S140 A183 K133 S134 A177 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 A 2.30 BS06 IOD A 5 G23 K26 N103 G17 K20 N97 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 A 2.30 BS07 IOD A 6 L143 N147 K150 E193 L137 N141 K144 E187 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 B 2.30 BS04 IOD B 3 A128 P129 M151 Y152 A122 P123 M145 Y146 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 B 2.30 BS05 IOD B 4 E22 L25 K26 E16 L19 K20 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 C 2.30 BS02 IOD C 1 V179 S180 A183 V173 S174 A177 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 C 2.30 BS03 IOD C 2 Q49 H76 A77 Q43 H70 A71 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 C 2.30 BS04 IOD C 3 Y85 L113 M127 Y79 L107 M121 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 C 2.30 BS05 IOD C 4 A128 P129 M151 A122 P123 M145 2.1.1.- Q2GKC7 SKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 D 2.30 BS02 IOD D 1 A128 P129 Y152 A123 P124 Y147 2.1.1.- Q2GKC7 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 D 2.30 BS04 IOD D 3 E116 A117 L118 Y145 E111 A112 L113 Y140 2.1.1.- Q2GKC7 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 D 2.30 BS05 IOD D 4 G115 E116 A119 G110 E111 A114 2.1.1.- Q2GKC7 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 D 2.30 BS07 IOD D 6 H58 S59 K81 H53 S54 K76 2.1.1.- Q2GKC7 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 E 2.30 BS02 IOD E 1 K139 L166 F167 S180 A183 K135 L162 F163 S176 A179 2.1.1.- Q2GKC7 SLSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 F 2.30 BS04 IOD F 3 T176 K178 V179 T171 K173 V174 2.1.1.- Q2GKC7 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4oa5 F 2.30 BS05 IOD F 4 G115 E116 A119 Q120 G110 E111 A114 Q115 2.1.1.- Q2GKC7 LSKQDEYLNKLFAVDTEGALKAHKTAPSELRMAQLGTVEGQMLQLLIRMAGIHSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEALAQLNTLKEMAPFDMIFIDANKSSYLAYLNWAKMYIRKGGLIVADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKYLSTIIPTSEGMMVSIKLT 4odj A 1.60 BS01 SAM A 1 H34 P35 D187 K189 S255 R257 F258 D266 H14 P15 D167 K169 S235 R237 F238 D246 2.5.1.6 Q5CKX0 EQFLFSSESVCSGHPDKLCDQISDAILDACLEQDPESFVACETCTKTGFIMVFGEITTKANVNYERVVRETVKEIGYDSEEKGLDYKTMDVIIKLEQQSNQIAGCVHVDKNVEDIGAGDQGMMFGYATNETKELMPLTHVLATSITRELDYIRMKGVSSRVGWLRPDGKAQVTVEYNCKHGVLIPKRIHTILVSVQHDENIENEEIREFVLENVIKKVCPSDLMDKETRILINPSGRFTIGGPAADAGLTGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSGAYMARLVAKSIVFSGLCSRCLVQVSYGIGIARPLSLYINTFGTAKDGYNDTKLLEIVNKVFDFRPGILIKQLNLKSPIFKKTSSGGHFGRSEKEFLWEKPIILQ 4odj A 1.60 BS02 3PO A 1 H34 D36 K189 R272 K273 H14 D16 K169 R252 K253 2.5.1.6 Q5CKX0 EQFLFSSESVCSGHPDKLCDQISDAILDACLEQDPESFVACETCTKTGFIMVFGEITTKANVNYERVVRETVKEIGYDSEEKGLDYKTMDVIIKLEQQSNQIAGCVHVDKNVEDIGAGDQGMMFGYATNETKELMPLTHVLATSITRELDYIRMKGVSSRVGWLRPDGKAQVTVEYNCKHGVLIPKRIHTILVSVQHDENIENEEIREFVLENVIKKVCPSDLMDKETRILINPSGRFTIGGPAADAGLTGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSGAYMARLVAKSIVFSGLCSRCLVQVSYGIGIARPLSLYINTFGTAKDGYNDTKLLEIVNKVFDFRPGILIKQLNLKSPIFKKTSSGGHFGRSEKEFLWEKPIILQ 4odj A 1.60 BS03 MG A 1 D36 K273 D16 K253 2.5.1.6 Q5CKX0 EQFLFSSESVCSGHPDKLCDQISDAILDACLEQDPESFVACETCTKTGFIMVFGEITTKANVNYERVVRETVKEIGYDSEEKGLDYKTMDVIIKLEQQSNQIAGCVHVDKNVEDIGAGDQGMMFGYATNETKELMPLTHVLATSITRELDYIRMKGVSSRVGWLRPDGKAQVTVEYNCKHGVLIPKRIHTILVSVQHDENIENEEIREFVLENVIKKVCPSDLMDKETRILINPSGRFTIGGPAADAGLTGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSGAYMARLVAKSIVFSGLCSRCLVQVSYGIGIARPLSLYINTFGTAKDGYNDTKLLEIVNKVFDFRPGILIKQLNLKSPIFKKTSSGGHFGRSEKEFLWEKPIILQ 4og3 A 2.01 BS01 2S6 A 1 S155 S178 E179 D180 H181 F238 C241 A242 M278 Y319 M322 Y323 W341 E363 S134 S157 E158 D159 H160 F217 C220 A221 M257 Y298 M301 Y302 W320 E342 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQ 4og4 A 1.45 BS01 2VK A 1 S178 F238 C241 A242 M278 Y319 M322 Y323 W341 E363 S157 F217 C220 A221 M257 Y298 M301 Y302 W320 E342 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 4og4 A 1.45 BS02 PGE A 1 W126 L129 K135 W105 L108 K114 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 4og5 A 1.63 BS01 2S7 A 1 S155 S178 E179 H181 F238 C241 A242 Y276 M278 Y319 M322 Y323 W341 E363 S134 S157 E158 H160 F217 C220 A221 Y255 M257 Y298 M301 Y302 W320 E342 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 4og6 A 1.49 BS01 2S9 A 1 S155 S178 D180 H181 F238 C241 A242 M278 Y319 M322 Y323 W341 E363 S134 S157 D159 H160 F217 C220 A221 M257 Y298 M301 Y302 W320 E342 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 4og8 A 1.53 BS01 TBF A 1 S154 S155 S133 S134 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 4og8 A 1.53 BS03 PGA A 1 W126 K135 W198 W105 K114 W177 O00255 24472025 GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMK 4ojq A 2.25 BS01 2SX A 1 V232 T254 G255 T269 G271 K272 A275 Y502 V47 T69 G70 T84 G86 K87 A90 Y312 K4KA16 24467709 DNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSILGIGTVLDQAETAGARLVVLATATPPGSVTVSHPNIEEVALSTTGEIPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYLDVSVIPDVVVVSTDALMTGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVAPGERPSGMFDSSVLCECYDAGCAWYELMPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMTCMSADLEVV 4ojq B 2.25 BS02 CA B 1 D437 S439 D229 S231 K4KA16 24467709 NSSPPAVPQSFQVAHLHAPTTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSILGIGTVLDQAETAGARLVVLATATPPGSVTVSHPNIEEVALSTTGEIPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTNGDVVVVSTDALMGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVAPGERPSGMFDSSVLCECYDAGCAWYELMPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMTCMSADLE 4ok3 A 2.30 BS01 2SY A 1 V232 T254 G255 T269 G271 K272 A275 A297 T298 A497 W501 Y502 V46 T68 G69 T83 G85 K86 A89 A111 T112 A294 W298 Y299 K4KA16 24467709 NSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSILGIGTVLDQAETAGARLVVLATATPPGSVTVSHPNIEEVALSTTGEIPFYGKAIPLEVIKGGRHLIFCHSKKKCDELAAKLNAVASVIPDVVVVSTDALMTGGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVAPGERPSGMFDSSVLCECYDAGCAWYELMPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPITKYIMTCMSADLEV 4ol8 A 3.10 BS01 NUC C 1 C114 V115 R118 L131 F185 G186 L187 V188 P191 N297 R300 K386 C82 V83 R86 L99 F153 G154 L155 V156 P159 N263 R266 K334 2.7.7.49,2.7.7.7,3.1.26.4 Q99315 PVWLQQKYREIIRNDLPPPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKDAPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLEYPAGELELLGIIKALHHFRYMLHGKHFTLRTNHARRVQRWLDDLATYDFTLEY 4ol8 A 3.10 BS02 NUC D 1 Y211 L212 D213 D214 L258 G259 K287 Q290 R291 G294 M295 Y298 R442 R445 Y179 L180 D181 D182 L224 G225 K253 Q256 R257 G260 M261 Y264 R373 R376 2.7.7.49,2.7.7.7,3.1.26.4 Q99315 PVWLQQKYREIIRNDLPPPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKDAPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLEYPAGELELLGIIKALHHFRYMLHGKHFTLRTNHARRVQRWLDDLATYDFTLEY 4ol8 B 3.10 BS01 NUC D 1 Q434 N435 K436 Q410 N411 K412 2.7.7.49,2.7.7.7,3.1.26.4 Q99315 KDTFCTLPVWLQQKYREIIRNDLPPRPAPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICDKSQWTEKQDKAIDKLKDALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLEYPAGELELLGIIKALHHFRYMLHGKHFTLRTNHISLLSLQNKNEPARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAVY 4ol8 E 3.10 BS01 NUC G 1 C114 D116 R118 N121 L131 Y156 F185 G186 L187 V188 P191 N297 R300 C83 D85 R87 N90 L100 Y125 F154 G155 L156 V157 P160 N264 R267 2.7.7.49,2.7.7.7,3.1.26.4 Q99315 PVWLQQKYREIIRNDLPPRPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPGTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKSPVLVPFNYRLTTDASKDGIGAVLEVGYFSKSLESAQGELELLGIIKALHHFRYMLHGKHFTLRTNHIEPARRVQRWLDDLATYDFTLE 4ol8 E 3.10 BS02 NUC H 1 Y156 Y211 L212 D213 L258 K287 Q290 R291 G294 Y298 R442 Y125 Y180 L181 D182 L227 K254 Q257 R258 G261 Y265 R365 2.7.7.49,2.7.7.7,3.1.26.4 Q99315 PVWLQQKYREIIRNDLPPRPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPGTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKSPVLVPFNYRLTTDASKDGIGAVLEVGYFSKSLESAQGELELLGIIKALHHFRYMLHGKHFTLRTNHIEPARRVQRWLDDLATYDFTLE 4onx A 2.80 BS01 ZN A 1 E72 H76 E38 H42 Q0TTS5 YMDEDVRNTLKETAFSISEIPFIQEDLSNGEINSRIQEYTKHFIEAINDVDIIVVADMRGVKYSHLDEKQIGQVFVNEDKKEVLTQGSSYYSLMKGSMGETLRWFQPVMYNGKQVGFIMVGKYYNEIQ 4opp A 2.30 BS01 11Z B 1 Q125 N126 A129 Q125 N126 A129 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4opp B 2.30 BS01 11Z B 1 P3 P4 A5 C6 L134 P3 P4 A5 C6 L134 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4opp C 2.30 BS01 NAG C 1 W66 K90 G91 A92 P96 N99 W66 K90 G91 A92 P96 N99 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4opp C 2.30 BS02 11Z D 1 P96 T97 Q150 P96 T97 Q150 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4opp D 2.30 BS03 11Z D 1 E24 W66 C67 R85 G91 A92 H93 G95 N99 E24 W66 C67 R85 G91 A92 H93 G95 N99 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4orv B 2.50 BS01 XXC B 1 P4 L134 P4 L134 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4orv C 2.50 BS01 NAG C 1 W66 G91 A92 P96 N99 W66 G91 A92 P96 N99 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4orv D 2.50 BS02 XXC D 1 W66 R85 A92 H93 G95 N99 W66 R85 A92 H93 G95 N99 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4otz A 1.36 BS01 CYS A 1 L70 T130 L131 S132 S153 N154 T155 F204 D280 F331 L18 T78 L79 S80 S101 N102 T103 F152 D228 F279 Q3MFZ5 NTIPIGIALAQTSNVALLGQEQVAGAKIAEKYFNDKGGVNGTPIKLIFQDTAGDEAGTINAFQTLINKDKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPEIGDYVARVSAPVSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQGLELVTVQKFQTTDTDFQSQATNAINLKPDLVIISGLAADGGNLVRQLRELGYQGAIIGGDGLNTSNVFAVCKALCDGVLIAQAYSPEYTGEINKAFRQAYVDQYKKEPPQFSAQAFAAVQVYVESLKALDTKNKVSKIQLPELRTELNKQLLTGKYNTPLGEISFTPIGEVVQKDFYVAQIKMEKDGSQGKFTFLK 4otz B 1.36 BS01 CYS B 1 L70 T130 L131 S132 S153 N154 T155 F204 D280 L18 T78 L79 S80 S101 N102 T103 F152 D228 Q3MFZ5 NTIPIGIALAQTSNVALLGQEQVAGAKIAEKYFNDKGGVNGTPIKLIFQDTAGDEAGTINAFQTLINKDKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPEIGDYVARVSAPVSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQGLELVTVQKFQTTDTDFQSQATNAINLKPDLVIISGLAADGGNLVRQLRELGYQGAIIGGDGLNTSNVFAVCKALCDGVLIAQAYSPEYTGEINKAFRQAYVDQYKKEPPQFSAQAFAAVQVYVESLKALDTKNKVSKIQLPELRTELNKQLLTGKYNTPLGEISFTPIGEVVQKDFYVAQIKMEKDGSQGKFTFLK 4ou1 A 1.25 BS01 2V7 A 1 K53 D56 P57 S58 F89 Y110 R182 D183 W184 T186 G187 K210 E211 K52 D55 P56 S57 F88 Y109 R181 D182 W183 T185 G186 K209 E210 4.1.-.- PRYLKGWLEDVVQLSLRRPSVRASRQRPIISLNERILEFNKRNITAIIAEYKRKDPSGLDVERDPIEYAKFMERYAVGLFISTEEKYFNGSYETLRKIASSVSIPILMYDFIVKESQIDDAYNLGADTVALIVKILTERELESLLEYARSYGMEPLIIINDENDLDIALRIGARFIGIAARDWETGEINKENQRKLISMIPSNVVKVAKEGISERNEIEELRKLGVNAFLIGSSLMRNPEKIKELIE 4oug C 2.46 BS01 LP5 C 1 L64 W66 K90 G91 A92 H93 A94 G95 P96 N99 Q150 L64 W66 K90 G91 A92 H93 A94 G95 P96 N99 Q150 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4oug D 2.46 BS01 LP5 C 1 A92 G95 P96 T97 W98 N99 K144 H146 D148 V149 Q150 P151 A92 G95 P96 T97 W98 N99 K144 H146 D148 V149 Q150 P151 Q9GK12 EDPPACGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQNVQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGISFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSPGDRLYEIIQTWSHYRA 4ovf A 2.05 BS01 CA A 1 N251 D253 N247 D249 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4ovf A 2.05 BS03 2VG A 1 R152 Y154 T172 G174 H175 R176 L177 P242 V247 M362 R148 Y150 T168 G170 H171 R172 L173 P238 V243 M358 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4ovf B 2.05 BS01 CA B 1 G280 V281 T293 A294 N295 G272 V273 T285 A286 N287 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4ovf B 2.05 BS03 2VG B 1 R152 Y154 L155 T172 G174 H175 R176 L177 V247 M362 R144 Y146 L147 T164 G166 H167 R168 L169 V239 M354 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4ovg A 1.90 BS01 2VF A 1 R152 Y154 T172 G174 R176 L177 P242 V247 V360 M362 R147 Y149 T167 G169 R171 L172 P237 V242 V355 M357 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4ovg A 1.90 BS02 CA A 1 T110 L111 T105 L106 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4ovg A 1.90 BS03 CA A 2 S181 S356 S176 S351 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4ovh A 2.25 BS01 2VE A 1 R152 Y154 T172 G174 H175 R176 L177 V247 V360 M362 R150 Y152 T170 G172 H173 R174 L175 V245 V358 M360 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4ovl A 1.70 BS02 1TD B 1 Q95 L102 A128 A129 W132 Q39 L46 A72 A73 W76 2.7.7.1 Q76353 24532034 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4owg A 1.55 BS01 PEP A 1 N11 K13 H95 E165 I170 G171 G209 G210 S211 L230 G232 G233 N9 K11 H93 E163 I168 G169 G207 G208 S209 L228 G230 G231 5.3.1.1 P00939 SRKFFVGGNWKMNGRKKNLGELITTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ 4oyq B 1.70 BS01 1X2 B 1 P2 M3 P34 Y37 H63 S64 I65 F114 P1 M2 P33 Y36 H62 S63 I64 F113 5.3.2.1,5.3.2.1 P14174 PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 4pnu B 1.90 BS01 2VD B 1 R152 Y154 G174 H175 R176 L177 P242 V247 M362 R146 Y148 G168 H169 R170 L171 P236 V241 M356 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4pnv A 1.86 BS03 CA A 3 Y153 N156 G157 P196 V237 Y153 N156 G157 P196 V237 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4pnv A 1.86 BS04 CA A 4 H255 Y310 S311 G312 H255 Y310 S311 G312 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4pnv A 1.86 BS05 CA A 5 L14 V17 S18 L33 L14 V17 S18 L33 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4pnv B 1.86 BS03 CA B 2 T4 V5 L59 V60 Q61 T4 V5 L59 V60 Q61 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4pnv B 1.86 BS04 CA B 3 T110 L111 P112 T110 L111 P112 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4pnw B 2.00 BS01 2VM B 1 Y153 Y154 T172 D173 G174 H175 R176 L177 P242 V360 M362 Y153 Y154 T172 D173 G174 H175 R176 L177 P242 V360 M362 2.7.7.7 U6NCW5 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM