2m7q A BS01 ZN A 1 C10 C13 H29 H33 C10 C13 H29 H33 Q86VP1 24239949 GPHMDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD 2rt5 A BS01 III B 1 L3515 K3516 R3548 I3549 A3550 Q3551 R3552 M3553 R3554 R3566 Y3602 G3610 I3611 L20 K21 R53 I54 A55 Q56 R57 M58 R59 R71 Y107 G115 I116 Q96T58 24268649 VDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAHRSLPLSEGGPPLRIAQRMRLEATQLEGVARRMTVETDYCLLLALPCGRDQEDVVSQTESLKAAFITYLQAKQAAGIINVPNPGSNQPAYVLQIFPPCEFSESHLSRLAPDLLASISNISPHLMIVIASV 3w2j A 1.42 BS01 QRO A 1 K43 N67 M69 G70 L71 N127 P131 N194 S195 K214 K44 N68 M70 G71 L72 N128 P132 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2j B 1.42 BS01 QRO B 1 K43 N67 M69 G70 L71 N127 S129 C130 P131 N194 S195 K214 K44 N68 M70 G71 L72 N128 S130 C131 P132 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2k A 1.54 BS01 KRO A 1 K43 N67 M69 G70 L71 L101 N127 P131 N194 S195 K44 N68 M70 G71 L72 L102 N128 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2k B 1.54 BS01 KRO B 1 K43 N67 M69 G70 L71 N127 S129 N194 S195 K44 N68 M70 G71 L72 N128 S130 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2l B 1.64 BS01 VRO B 1 K43 N67 M69 G70 L71 N127 S129 C130 P131 N132 N194 S195 K44 N68 M70 G71 L72 N128 S130 C131 P132 N133 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2m A 1.58 BS01 ZRO A 1 K43 N53 N67 S68 M69 G70 L71 N127 P131 N194 S195 K214 K44 N54 N68 S69 M70 G71 L72 N128 P132 N195 S196 K215 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2m B 1.58 BS01 ZRO B 1 K43 T46 R50 N67 M69 G70 L71 S99 L101 N127 S129 P131 N194 S195 K44 T47 R51 N68 M70 G71 L72 S100 L102 N128 S130 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3w2n A 1.96 BS01 ROD A 1 K43 N67 M69 G70 L71 S99 L101 N127 C130 P131 N194 S195 K44 N68 M70 G71 L72 S100 L102 N128 C131 P132 N195 S196 1.3.98.1 Q4D3W2 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMAFPLGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAMVRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGVKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGNGLVIDAESESVVIKPKQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTALQEEGPGIFTRLEDELLEIMARKGYRTLEEFRGRVKTIE 3wjw A 1.59 BS01 U6M A 1 A18 D20 K42 D70 K72 M126 S127 P180 Q185 G202 R203 A8 D10 K32 D60 K62 M116 S117 P170 Q175 G192 R193 4.1.1.23 O26232 24151964 VMNRLILAMDLMNRDDALRVTGEVREYIDTVKIGYPLVLSEGMDIIAEFRKRFGCRIIADFKVADIPETNEKICRATFKAGADAIIVHGFPGADSVRACLNVAEEMGREVFLLTEMSHPGAEMFIQGAADEIARMGVDLGVKNYVGPSTRPERLSRLREIIGQDSFLISPGVGAQGGDPGETLRFADAIIVGRSIYLADNPAAAAAGIIESIKDL 3wk0 A 1.41 BS01 O7M A 1 A18 D20 K42 D70 K72 I96 M126 S127 V155 P180 Q185 G202 R203 A8 D10 K32 D60 K62 I86 M116 S117 V145 P170 Q175 G192 R193 4.1.1.23 O26232 24151964 VMNRLILAMDLMNRDDALRVTGEVREYIDTVKIGYPLVLSEGMDIIAEFRKRFGCRIIADFKVADIPETNEKICRATFKAGADAIIVHGFPGADSVRACLNVAEEMGREVFLLTEMSHPGAEMFIQGAADEIARMGVDLGVKNYVGPSTRPERLSRLREIIGQDSFLISPGVGAQGGDPGETLRFADAIIVGRSIYLADNPAAAAAGIIESIKDL 3wk2 A 1.69 BS01 O7M A 1 A18 D20 K42 D70 A72 L123 M126 S127 P180 Q185 G202 R203 A8 D10 K32 D60 A62 L113 M116 S117 P170 Q175 G192 R193 4.1.1.23 O26232 24151964 VMNRLILAMDLMNRDDALRVTGEVREYIDTVKIGYPLVLSEGMDIIAEFRKRFGCRIIADFAVADIPETNEKICRATFKAGADAIIVHGFPGADSVRACLNVAEEMGREVFLLTEMSHPGAEMFIQGAADEIARMGVDLGVKNYVGPSTRPERLSRLREIIGQDSFLISPGVGAQGGDPGETLRFADAIIVGRSIYLADNPAAAAAGIIESIKDL 4bge A 2.25 BS01 PYW A 1 I21 A94 I95 G96 M103 M147 D148 F149 A157 Y158 M161 K165 G192 P193 I194 M199 I19 A92 I93 G94 M101 M145 D146 F147 A155 Y156 M159 K163 G190 P191 I192 M197 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge B 2.25 BS01 PYW B 1 I21 A94 I95 G96 M103 M147 D148 F149 Y158 M161 K165 G192 P193 I194 M199 I202 I215 L218 I19 A92 I93 G94 M101 M145 D146 F147 Y156 M159 K163 G190 P191 I192 M197 I200 I213 L216 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge C 2.25 BS01 PYW C 1 I21 A94 I95 G96 M103 M147 D148 F149 A157 Y158 M161 K165 A191 G192 P193 I194 I19 A92 I93 G94 M101 M145 D146 F147 A155 Y156 M159 K163 A189 G190 P191 I192 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIREEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge D 2.25 BS01 PYW D 1 I21 A94 I95 G96 M103 M147 D148 F149 Y158 M161 K165 G192 P193 I194 I215 I19 A92 I93 G94 M101 M145 D146 F147 Y156 M159 K163 G190 P191 I192 I198 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bge F 2.25 BS01 PYW F 1 I21 A94 I95 G96 M103 M147 D148 F149 A157 Y158 M161 K165 A191 G192 P193 I194 M199 I202 I19 A92 I93 G94 M101 M145 D146 F147 A155 Y156 M159 K163 A189 G190 P191 I192 M197 I200 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bgi C 2.09 BS01 NAD C 1 G14 I16 S20 F41 L63 D64 V65 A94 I95 G96 I122 M147 D148 F149 K165 A191 G192 I194 G12 I14 S18 F39 L61 D62 V63 A92 I93 G94 I120 M145 D146 F147 K163 A189 G190 I192 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIREEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bgi D 2.09 BS01 NAD D 1 G14 I16 S20 I21 F41 L63 D64 V65 A94 I95 G96 I122 M147 D148 F149 M161 K165 A191 G192 P193 I194 G12 I14 S18 I19 F39 L61 D62 V63 A92 I93 G94 I120 M145 D146 F147 M159 K163 A189 G190 P191 I192 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHAIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bii A 1.95 BS02 PYW A 1 I21 S94 I95 G96 M103 M147 D148 F149 A157 Y158 M161 K165 G192 P193 I194 I19 S92 I93 G94 M101 M145 D146 F147 A155 Y156 M159 K163 G190 P191 I192 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bii D 1.95 BS01 PYW D 1 S94 I95 G96 M103 M147 D148 F149 A157 Y158 K165 G192 P193 I194 M199 S88 I89 G90 M97 M141 D142 F143 A151 Y152 K159 G186 P187 I188 M193 1.3.1.9 P0A5Y6 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL 4bqd A 2.45 BS01 III C 1 T12 T14 A27 F28 K29 A30 D31 D32 A37 I38 F44 N45 I46 F47 I55 G57 N64 T11 T13 A26 F27 K28 A29 D30 D31 A36 I37 F43 N44 I45 F46 I54 G56 N63 Q59EE5 SEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 4bqd B 2.45 BS01 III D 1 A27 F28 K29 A30 D31 D32 C35 K36 A37 F44 N45 I46 F47 F54 I55 G57 N64 A13 F14 K15 A16 D17 D18 C21 K22 A23 F30 N31 I32 F33 F40 I41 G43 N50 Q59EE5 ELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRD 4c2c A 1.90 BS01 III B 1 G255 L257 V337 Q338 G210 L212 V292 Q293 A5HUP7 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2c A 1.90 BS02 III C 1 F111 G113 I114 G115 A116 E117 V118 L160 V164 I167 R168 F66 G68 I69 G70 A71 E72 V73 L115 V119 I122 R123 A5HUP7 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d A 2.70 BS01 III E 1 G254 G255 Y256 L257 S309 A310 V337 Q338 A340 L353 G209 G210 Y211 L212 S264 A265 V292 Q293 A295 L308 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d A 2.70 BS02 III M 1 F111 G113 I114 G115 A116 V118 F131 L160 I167 R168 L199 F66 G68 I69 G70 A71 V73 F86 L115 I122 R123 L154 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d B 2.70 BS01 III F 1 G254 G255 Y256 L257 S309 A310 K334 V337 Q338 A340 Y354 G209 G210 Y211 L212 S264 A265 K289 V292 Q293 A295 Y309 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d B 2.70 BS02 III N 1 Q102 F111 G113 I114 G115 A116 V118 F131 L160 N161 I167 R168 Q57 F66 G68 I69 G70 A71 V73 F86 L115 N116 I122 R123 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d C 2.70 BS01 III G 1 G255 Y256 L257 S309 A310 K334 V337 Q338 A340 G210 Y211 L212 S264 A265 K289 V292 Q293 A295 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d C 2.70 BS02 III O 1 Q102 F111 G113 I114 G115 A116 V118 F131 V164 Q57 F66 G68 I69 G70 A71 V73 F86 V119 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d D 2.70 BS01 III H 1 Y256 L257 Q338 Q339 Y121 L122 Q203 Q204 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2d D 2.70 BS02 III P 1 F103 G254 G255 S309 A310 K334 Q338 K350 F58 G119 G120 S174 A175 K199 Q203 K215 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2f A 2.40 BS01 III B 1 G255 L257 S309 V337 Q338 G210 L212 S264 V292 Q293 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIAGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2f A 2.40 BS02 III C 1 Y91 S106 F111 G113 I114 G115 A116 E117 V118 L160 V164 A308 F332 Y46 S61 F66 G68 I69 G70 A71 E72 V73 L115 V119 A263 F287 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIAGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c2g A 1.90 BS01 III B 1 G254 G255 L257 A309 A310 I313 K334 V337 Q338 G209 G210 L212 A264 A265 I268 K289 V292 Q293 3.4.21.102 O35002 24243021 SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDKQTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISINGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSAAASEILAGALKEAGHYDVVGDTSFGKGTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGPLQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQDQNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF 4c4e A 2.60 BS01 4T9 A 1 I531 A551 K553 I586 M602 E603 G605 I607 L654 I16 A36 K38 I71 M87 E88 G90 I92 L139 2.7.12.1 P33981 24256217 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPQVGTVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 4c4f A 2.36 BS01 7CE A 1 I531 Q541 A551 K553 I586 M602 E603 C604 G605 N606 D608 L654 I663 I17 Q27 A37 K39 I72 M88 E89 C90 G91 N92 D94 L140 I149 2.7.12.1 P33981 24256217 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQQVGTVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 4c4g A 2.65 BS01 7RO A 1 I531 A551 K553 L575 I586 M602 E603 C604 G605 I607 D608 S611 L654 I663 I17 A37 K39 L61 I72 M88 E89 C90 G91 I93 D94 S97 L140 I149 2.7.12.1 P33981 24256217 FQSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIAVGTVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 4c4h A 2.80 BS01 7RO A 1 I531 G532 V539 Q541 A551 K553 M602 E603 C604 G605 I607 D608 S611 L654 I663 I16 G17 V23 Q25 A35 K37 M86 E87 C88 G89 I91 D92 S95 L138 I147 2.7.12.1 P33981 24256217 QSMSVKGRIYSILKQIGSGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIATVNYMPPEAIKDISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 4c4i A 2.65 BS01 X20 A 1 I531 V539 Q541 A551 K553 I586 M602 E603 C604 G605 I607 D608 S611 L654 I663 I16 V24 Q26 A36 K38 I71 M87 E88 C89 G90 I92 D93 S96 L139 I148 2.7.12.1 P33981 24256217 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMTVNYMPPEAIKDMISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 4c4j A 2.50 BS01 X21 A 1 I531 G532 V539 Q541 A551 K553 E571 M602 E603 C604 G605 N606 I607 D608 S611 L654 I663 M671 P673 I16 G17 V24 Q26 A36 K38 E56 M87 E88 C89 G90 N91 I92 D93 S96 L139 I148 M156 P158 2.7.12.1 P33981 24256217 QSMSVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTVGTVNYMPPEAIKDMSSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQ 4c9k A 2.18 BS01 HEM A 1 P102 T103 H110 R114 I117 L121 F165 L252 L253 G256 T260 V261 F264 F297 V303 D305 R307 T357 F358 A359 H363 C365 A366 G367 A371 P93 T94 H101 R105 I108 L112 F156 L243 L244 G247 T251 V252 F255 F288 V294 D296 R298 T348 F349 A350 H354 C356 A357 G358 A362 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9k A 2.18 BS02 CAH A 1 W89 Y98 T103 T187 L252 L255 G256 T260 V303 V404 W80 Y89 T94 T178 L243 L246 G247 T251 V294 V395 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9k A 2.18 BS03 CAM A 1 W89 Y98 T103 L252 L255 G256 T260 V303 W80 Y89 T94 L243 L246 G247 T251 V294 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9k B 2.18 BS01 HEM B 1 P102 T103 H110 R114 I117 F165 L252 L253 G256 G257 T260 V261 F264 F297 V303 D305 R307 T357 F358 A359 H363 C365 G367 A371 P92 T93 H100 R104 I107 F155 L242 L243 G246 G247 T250 V251 F254 F287 V293 D295 R297 T347 F348 A349 H353 C355 G357 A361 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9l A 1.80 BS01 HEM A 1 Y77 P102 T103 H110 R114 I117 L121 F165 L252 L253 G256 G257 T260 V261 F264 F297 V302 V303 D305 R307 T357 F358 A359 H363 C365 A366 G367 L370 A371 Y68 P93 T94 H101 R105 I108 L112 F156 L243 L244 G247 G248 T251 V252 F255 F288 V293 V294 D296 R298 T348 F349 A350 H354 C356 A357 G358 L361 A362 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9l A 1.80 BS02 CAM A 1 W89 Y98 T103 T187 L252 L255 V303 W80 Y89 T94 T178 L243 L246 V294 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9l B 1.80 BS02 CAM B 1 W89 Y98 T103 T187 L252 L255 V303 D305 V404 W79 Y88 T93 T177 L242 L245 V293 D295 V394 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9m A 1.80 BS02 GOL A 1 W89 T103 L252 V303 V404 W80 T94 L243 V294 V395 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9n A 2.20 BS02 CAM A 1 W89 Y98 L252 L255 G256 T260 V303 W80 Y89 L243 L246 G247 T251 V294 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLNTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9n B 2.20 BS01 HEM B 1 P102 T103 H110 R114 F165 L252 L253 G256 G257 T260 V261 F264 V303 D305 R307 T357 F358 A359 H363 C365 G367 P92 T93 H100 R104 F155 L242 L243 G246 G247 T250 V251 F254 V293 D295 R297 T347 F348 A349 H353 C355 G357 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLNTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9n B 2.20 BS02 CAH B 1 W89 Y98 T103 T187 L252 L255 G256 V303 V404 W79 Y88 T93 T177 L242 L245 G246 V293 V394 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLNTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9n B 2.20 BS03 CAM B 1 W89 Y98 T103 T187 L252 L255 G256 V303 W79 Y88 T93 T177 L242 L245 G246 V293 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLNTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9o A 1.98 BS02 CAM A 1 I88 W89 Y98 T103 L252 L255 V303 D305 I403 I79 W80 Y89 T94 L243 L246 V294 D296 I394 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLNTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9o B 1.98 BS02 CAM B 1 I88 W89 Y98 T103 L252 L255 V303 D305 V404 I78 W79 Y88 T93 L242 L245 V293 D295 V394 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLNTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9p A 1.80 BS02 CAM A 1 W89 Y98 T103 T187 L255 G256 V303 W80 Y89 T94 T178 L246 G247 V294 Q2GB12 24261604 QKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDAVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4c9p B 1.80 BS01 HEM B 1 T103 H110 R114 L121 F165 L252 L253 G256 G257 A260 V261 F264 F297 V303 D305 R307 T357 F358 A359 H363 C365 G367 A371 T93 H100 R104 L111 F155 L242 L243 G246 G247 A250 V251 F254 F287 V293 D295 R297 T347 F348 A349 H353 C355 G357 A361 Q2GB12 24261604 KHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPFTGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKGLNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLGLLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKPMPDDRALGLVSLLLLGGLDAVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRFAVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQ 4cdr A 3.15 BS01 III E 1 H496 H498 H499 N557 P559 Y632 T633 K634 Q839 V895 H185 H187 H188 N246 P248 Y321 T322 K323 Q509 V565 2.4.1.255 O15294 24256146 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4cdr A 3.15 BS02 UDP E 1 Q839 K842 L866 F868 V895 A896 K898 H901 R904 H920 T921 T922 D925 Q509 K512 L536 F538 V565 A566 K568 H571 R574 H590 T591 T592 D595 2.4.1.255 O15294 24256146 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4cdr B 3.15 BS01 III F 1 H496 N557 P559 Y632 T633 K634 Q839 F868 V895 H185 N246 P248 Y321 T322 K323 Q509 F538 V565 2.4.1.255 O15294 24256146 SCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKIYDNRIVLNGIDLKAFLDSLPDVKIVKMLNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK 4cfs A 1.94 BS01 HQD A 1 W36 H38 H100 S101 H102 L143 W160 M177 W185 S188 I192 W34 H36 H98 S99 H100 L141 W158 M175 W183 S186 I190 1.13.11.48 O31266 DTYLHETLVFDNKLSYIDNQRDTDGPAILLLPGWCHDHRVYKYLIQELDADFRVIVPNWRGHGLSPSEVPDFGYQEQVKDALEILDQLGVETFLPVSHSHGGWVLVELLEQAGPERAPRGIIMDWLMWAPKPDFAKSLTLLKDPERWREGTHGLFDVWLDGHDEKRVRHHLLEEMADYGYDCWGRSGRVIEDAYGRNGSPMQMMANLTKTRPIRHIFSQPTEPEYEKINSDFAEQHPWFSYAKLGGPTAFPAIDVPDRAAVHIREFATAIRQG 4cgd A 2.00 BS01 8P3 A 1 E170 H171 T174 E114 H115 T118 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cgd B 2.00 BS02 8P3 B 1 E170 H171 T174 M178 E114 H115 T118 M122 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cgg B 1.75 BS02 K5Q B 3 Q95 E96 Y99 L102 A129 Q39 E40 Y43 L46 A73 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4cgj A 2.15 BS01 NZL A 1 D167 Q168 E170 H171 T174 M178 D111 Q112 E114 H115 T118 M122 2.7.7.7 Q76353 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ 4fnm A 1.80 BS01 DPF A 1 G135 G136 G137 S218 A219 W251 Y457 H471 T472 G134 G135 G136 S217 A218 W250 Y456 H470 T471 Q25252 23733941 NFNVSLMEKLKWKIKCIENKFLNYRLTTNETVVAETEYGKVKGVKRLTVYDDSYYSFEGIPYAQPPVGELRFKAPQRPTPWDGVRDCCNHKDKSVQVDFITGKVCGSEDCLYLSVYTNNLNPETKRPVLVYIHGGGFIIGENHRDMYGPDYFIKKDVVLINIQYRLGALGFLSLNSEDLNVPGNAGLKDQVMALRWIKNNCANFGGNPDNITVFGESAGAASTHYMMLTEQTRGLFHRGILMSGNAICPWANTQCQHRAFTLAKLAGYKGEDNDKDVLEFLMKAKPQDLIKLEEKVLTLEERTNKVMFPFGPTVEPYQTADCVLPKHPREMVKTAWGNSIPTMMGNTSYEGLFFTSILKQMPLLVKELETCVNFVPSELADAERTAPETLEMGAKIKKAHVTGETPTADNFMDLCSHFYFWFPMHRLLQLRFNHTSGTPVYLYRFDFDSEDLINPYRIMRSGRGVKGVSHTDELTYFFWNQLAKRMPKESREYKTIERMTGIWTQFATTGNPYSNEIEGMENVSWDPIEKSDEVYKCLNISDELKMIDVPEMGKIKQWESMFEKHRDLF 4hjs A 1.22 BS01 18J A 1 K15 L17 S52 E54 L110 S117 T118 T119 K6 L8 S43 E45 L101 S108 T109 T110 P02766 24180271 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4hjt A 1.45 BS01 18A A 1 K15 L17 E54 L110 S117 T118 K6 L8 E45 L101 S108 T109 P02766 24180271 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP 4hju B 1.35 BS01 16L B 1 L17 T106 L110 S117 T118 L8 T97 L101 S108 T109 P02766 24180271 CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN 4i5b A 2.12 BS01 III C 1 Q9 F24 S53 F54 G58 N62 C65 D66 N69 I72 M73 R76 Q8 F23 S52 F53 G57 N61 C64 D65 N68 I71 M72 R75 P01903 KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIACDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4i5b B 2.12 BS01 III C 1 L11 F13 Y47 P56 D57 Y60 W61 L67 Q70 R71 Y78 H81 N82 L10 F12 Y46 P55 D56 Y59 W60 L66 Q69 R70 Y77 H80 N81 P04229 DTRPRFLWQLKFECHFFNGTERVRLLERSIYNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSE 4i5b D 2.12 BS01 III F 1 Q9 F24 S53 F54 G58 N62 C65 D66 N69 R76 Q8 F23 S52 F53 G57 N61 C64 D65 N68 R75 P01903 KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIACDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPE 4i7w A 1.30 BS01 LYS A 1 S48 P49 L51 H53 H56 Y106 S48 P49 L51 H53 H56 Y106 4.2.1.52 F0L8Z6 MFKGSIPALITPFTDNGAVDEQAFAAHVEWQIAEGSNGLVPVGTTGESPTLSHDEHKRVVELCIEVAAKRVPVIAGAGSNNTDEAIELALHAQDAGADALLVVTPYYNKPTQKGLFAHFSAVAEAVKLPIVIYNIPPRSVVDMSPETMGALVKAHKNIVGVKDATGKLDRVSEQRISCGKDFIQLSGEDSTALGFNAHGGVGCISVSANVAPRLCSEFQAAMLAGDYAKALEYQDRLMPLHRAIFMEPGVCGTKYALSKTRGCNRKVRSPLMSTLEPATEAAIDAALKHAGLMN 4i7w A 1.30 BS02 LYS B 1 N80 E84 N80 E84 4.2.1.52 F0L8Z6 MFKGSIPALITPFTDNGAVDEQAFAAHVEWQIAEGSNGLVPVGTTGESPTLSHDEHKRVVELCIEVAAKRVPVIAGAGSNNTDEAIELALHAQDAGADALLVVTPYYNKPTQKGLFAHFSAVAEAVKLPIVIYNIPPRSVVDMSPETMGALVKAHKNIVGVKDATGKLDRVSEQRISCGKDFIQLSGEDSTALGFNAHGGVGCISVSANVAPRLCSEFQAAMLAGDYAKALEYQDRLMPLHRAIFMEPGVCGTKYALSKTRGCNRKVRSPLMSTLEPATEAAIDAALKHAGLMN 4i7w B 1.30 BS02 LYS B 1 S48 P49 L51 H56 Y106 S48 P49 L51 H56 Y106 4.2.1.52 F0L8Z6 MFKGSIPALITPFTDNGAVDEQAFAAHVEWQIAEGSNGLVPVGTTGESPTLSHDEHKRVVELCIEVAAKRVPVIAGAGSNNTDEAIELALHAQDAGADALLVVTPYYNKPTQKGLFAHFSAVAEAVKLPIVIYNIPPRSVVDMSPETMGALVKAHKNIVGVKDATGKLDRVSEQRISCGKDFIQLSGEDSTALGFNAHGGVGCISVSANVAPRLCSEFQAAMLAGDYAKALEYQDRLMPLHRAIFMEPGVCGTKYALSKTRGCNRKVRSPLMSTLEPATEAAIDAALKHAGLMN 4i97 A 2.15 BS01 GSH A 1 P12 L34 H39 H51 T52 I53 E65 S66 R67 M102 P11 L33 H38 H50 T51 I52 E64 S65 R66 M101 ADLYYLPGSSPCRSVIMVAKAIGLELNKKLLDLSTGEHLKPEFVKINPQHTIPTLVDNGFALWESRAILVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPELYKKMEAAVEFLNTFLEGQTYAAGDSLTIADIALLATMSSFEVAGYDFSKYENVNKWYANAKKVTPGWDENWAGCQEFKKYF 4i97 B 2.15 BS01 GSH B 1 P12 L34 H39 H51 T52 I53 E65 S66 R67 P11 L33 H38 H50 T51 I52 E64 S65 R66 ADLYYLPGSSPCRSVIMVAKAIGLELNKKLLDLSTGEHLKPEFVKINPQHTIPTLVDNGFALWESRAILVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPELYKKMEAAVEFLNTFLEGQTYAAGDSLTIADIALLATMSSFEVAGYDFSKYENVNKWYANAKKVTPGWDENWAGCQEFKKYF 4il5 A 2.03 BS01 ILE A 1 K58 T85 G87 N88 T89 Q159 F160 G192 G236 A239 K57 T84 G86 N87 T88 Q158 F159 G191 G235 A238 2.5.1.47 O15570 23747298 EQISISSPRKRIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTEGKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYTANEIWEDTDGEVDIVVSAVGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKKEFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPSCGERYLSTDLYKIKDEGTKIQILDSLLNE 4ip4 A 2.13 BS01 MG A 1 K218 D246 E272 E299 K217 D245 E271 E298 Q1GLV3 TKITGLRTYDLRFPTSEGLDGSDAMNPDPDYSAAYVILETEGTHEGHGLTFTIGRGNEICIAAIKALGALVVGLDLDWIREDMGRFWRHVTGDSQLRWIGPDKGAIHLAAGAVVNAVWDLWAKDTGKPVWRLVADMSPAEILRLIDFRYLTDVLAPEEALDLLKAAEPGKEERIARLIEEGYPCYTTSAGWLGYSDEKLRRLCREARAAGFTHTKFKVGRDLSDDIRRLTIAREELGEDMNIMIDANQVWEVDEAIDWVNRLAFARPLFIEEPTSPDDVLGHKAIREGVAPIKVATGEMCQNRIMFKQFIASGALDIVQIDSCRMGGLNEVLAVMLVAAKYDLPVWPHAGGVGLCEYVQHMSMIDYVAICGEKDSKRIEYVDHLHEHFKHPCIVTGGAYQAPHAPGFSIEMKEDTLDAFLF 4ip5 A 2.13 BS01 EHM A 1 G22 D24 Y32 W192 K216 K218 D246 N248 E272 E299 H349 G21 D23 Y31 W191 K215 K217 D245 N247 E271 E298 H348 Q1GLV3 TKITGLRTYDLRFPTSEGLDGSDAMNPDPDYSAAYVILETEGTHEGHGLTFTIGRGNEICIAAIKALGALVVGLDLDWIREDMGRFWRHVTGDSQLRWIGPDKGAIHLAAGAVVNAVWDLWAKDTGKPVWRLVADMSPAEILRLIDFRYLTDVLAPEEALDLLKAAEPGKEERIARLIEEGYPCYTTSAGWLGYSDEKLRRLCREARAAGFTHTKFKVGRDLSDDIRRLTIAREELGEDMNIMIDANQVWEVDEAIDWVNRLAFARPLFIEEPTSPDDVLGHKAIREGVAPIKVATGEMCQNRIMFKQFIASGALDIVQIDSCRMGGLNEVLAVMLVAAKYDLPVWPHAGGVGLCEYVQHMSMIDYVAICGEKDSKRIEYVDHLHEHFKHPCIVTGGAYQAPHAPGFSIEMKEDTLDAFLF 4jbl B 2.00 BS01 MET B 1 K58 T85 S86 N88 T89 M136 Q159 F160 G192 G236 I237 A239 K57 T84 S85 N87 T88 M135 Q158 F159 G191 G235 I236 A238 2.5.1.47 O15570 23747298 EQISISSPRKRIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTEGKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYTANEIWEDTDGEVDIVVSAVGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKKEFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPSCGERYLSTDLYKIKDEGTKIQILDSLLN 4jbn A 1.87 BS01 III C 1 K58 T85 S86 G87 N88 T89 M136 Q159 F160 G192 T193 G236 K57 T84 S85 G86 N87 T88 M135 Q158 F159 G191 T192 G235 O15570 23747298 EQISISSPRKRIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILTEGKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYTANEIWEDTDGEVDIVVSAVGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKKEFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPSCGERYLSTDLYKIKDEGTKIQILDSLLNE 4jhh A 2.20 BS01 H35 A 1 T66 Q68 Y82 V84 I98 F100 Y133 G137 R140 F144 T71 Q73 Y87 V89 I103 F105 Y138 G142 R145 F149 P93330 IDPFTMGVITSESEYVSSLSAEKLYRGIVEDGNIIYPKALPRFIEKAETLEGDGGPGTIKKLTFVGDFGSTKQHIDMVDRENCAYTYSVYEGIALSDQPLEKIVFEFKLVPTPEEGCIVKSTTKYYTKGDDIELSKDYLEAGIERFEGFTKAVESFLLANPDY 4jhi A 2.60 BS01 EMU A 1 T66 Q68 Y82 V84 I98 F100 Y133 A136 G137 R140 T70 Q72 Y86 V88 I102 F104 Y137 A140 G141 R144 P93330 DPFTMGVITSESEYVSSLSAEKLYRGIVEDGNIIYPKALPRFIEKAETLEGDGGPGTIKKLTFVGDFGSTKQHIDMVDRENCAYTYSVYEGIALSDQPLEKIVFEFKLVPTPEEGCIVKSTTKYYTKGDDIELSKDYLEAGIERFEGFTKAVESFLLANPDY 4jpm A 1.14 BS01 MA4 A 1 V224 P226 I231 I246 A248 V261 I263 I279 A280 A284 I287 E288 V199 P201 I206 I220 A222 V234 I236 I252 A253 A257 I260 E261 3.5.2.6 P0AD64 24219313 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4jpm A 1.14 BS02 MA4 A 2 L220 T235 R244 N276 I279 L195 T210 R218 N249 I252 3.5.2.6 P0AD64 24219313 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4jpm A 1.14 BS03 1OG A 1 M69 S70 Y105 S130 N132 G236 A237 M44 S45 Y80 S105 N107 G211 A212 3.5.2.6 P0AD64 24219313 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4k9f A 1.75 BS01 FE A 1 C5 C8 Y10 C38 I40 C41 C6 C9 Y11 C39 I41 C42 P24297 24100333 MAKWVCKICGYIYDEDAGDPDNGISPGTKFEELPDDWVCPICGAPKSEFEKLE 4kty A 1.98 BS01 III C 1 Y214 W279 Y283 S290 Q313 C314 W315 F339 M350 I352 T365 D367 S368 V369 W370 N371 Y372 H373 T398 L439 Y441 H459 Y200 W265 Y269 S276 Q299 C300 W301 F325 M336 I338 T351 D353 S354 V355 W356 N357 Y358 H359 T384 L425 Y427 H443 2.3.2.13 P00488 24115223 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 4kty A 1.98 BS02 CA A 1 A264 N267 A268 K269 D271 A250 N253 A254 K255 D257 2.3.2.13 P00488 24115223 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 4kty A 1.98 BS03 CA A 2 D343 D345 N347 Q349 D351 D367 D329 D331 N333 Q335 D337 D353 2.3.2.13 P00488 24115223 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 4kty A 1.98 BS04 CA A 3 N436 A457 T458 E485 E490 N422 A441 T442 E469 E474 2.3.2.13 P00488 24115223 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 4kty B 1.98 BS01 III D 1 Y214 R223 W279 S290 Q313 C314 W315 F339 M350 I352 T365 D367 S368 V369 W370 N371 Y372 H373 T398 Q400 L439 Y441 H459 Y200 R209 W265 S276 Q299 C300 W301 F325 M336 I338 T351 D353 S354 V355 W356 N357 Y358 H359 T384 Q386 L425 Y427 H440 2.3.2.13 P00488 24115223 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPS 4kty B 1.98 BS04 CA B 3 N436 A457 E485 E490 N422 A438 E466 E471 2.3.2.13 P00488 24115223 PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPS 4l80 A 2.01 BS01 1VU A 1 H32 F33 K40 I41 R44 N58 A62 R92 A183 P246 L274 P276 H31 F32 K39 I40 R43 N57 A61 R91 A182 P245 L273 P275 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAY 4l80 A 2.01 BS02 OXL A 1 R92 E157 G181 P182 A183 D184 P246 W272 R91 E156 G180 P181 A182 D183 P245 W271 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAY 4l80 A 2.01 BS03 MG A 1 E157 D184 E156 D183 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAY 4l80 A 2.01 BS04 1VU B 1 M316 D318 M315 D317 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAY 4l80 B 2.01 BS02 OXL B 1 R92 L155 E157 G181 P182 A183 D184 P246 W272 R91 L154 E156 G180 P181 A182 D183 P245 W271 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAYGL 4l80 C 2.01 BS01 1VU A 1 M311 M316 D318 M310 M315 D317 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAYGL 4l80 D 2.01 BS01 1VU D 1 H32 F33 K40 I41 R44 N58 D61 A62 R92 P246 L274 P276 H31 F32 K39 I40 R43 N57 D60 A61 R91 P242 L270 P272 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAYGL 4l80 E 2.01 BS01 1VU E 1 H32 F33 K40 I41 R44 D61 A62 R92 A183 P246 W272 L274 P276 H31 F32 K39 I40 R43 D60 A61 R91 A182 P242 W268 L270 P272 4.1.3.24 A9WC35 24206647 RKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAYGL 4l9y A 2.10 BS01 MG A 1 D45 E141 D168 D44 E140 D167 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4l9y A 2.10 BS02 1VU B 1 L297 D299 L296 D298 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4l9y B 2.10 BS01 1VU B 1 F19 G20 R24 L27 K30 M31 S46 R76 A167 I180 P223 W249 I251 H252 P253 F18 G19 R23 L26 K29 M30 S45 R75 A166 I179 P222 W248 I250 H251 P252 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTP 4l9y B 2.10 BS02 GLV B 1 R76 E141 G165 A166 A167 D168 P223 W249 R75 E140 G164 A165 A166 D167 P222 W248 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTP 4l9y D 2.10 BS02 MG D 1 E141 D168 E140 D167 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPS 4l9y E 2.10 BS01 MG E 1 E44 D45 E141 D168 E43 D44 E140 D167 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPS 4l9z A 2.01 BS01 COA A 1 F19 G20 P21 L27 K30 M31 S46 R76 I251 H252 P253 F17 G18 P19 L25 K28 M29 S44 R74 I249 H250 P251 4.1.3.24 Q3J5L6 24206647 FRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4l9z A 2.01 BS04 COA B 1 V292 L297 D299 V290 L295 D297 4.1.3.24 Q3J5L6 24206647 FRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4l9z B 2.01 BS01 COA B 1 F19 G20 P21 R24 L27 K30 M31 D42 S46 R76 W249 I251 H252 P253 F18 G19 P20 R23 L26 K29 M30 D41 S45 R75 W248 I250 H251 P252 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4l9z C 2.01 BS03 OXL C 1 R76 E141 G165 A166 A167 D168 P223 R75 E140 G164 A165 A166 D167 P222 4.1.3.24 Q3J5L6 24206647 SFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4l9z F 2.01 BS02 COA F 1 F19 G20 P21 L27 M31 S46 R76 W249 I251 H252 P253 F17 G18 P19 L25 M29 S44 R74 W247 I249 H250 P251 4.1.3.24 Q3J5L6 24206647 FRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEM 4ly6 A 3.60 BS01 08T A 1 Y139 V140 F141 S169 G170 G172 K173 E174 D238 E239 N280 V356 R357 K360 Y2 V3 F4 S32 G33 G35 K36 E37 D101 E102 N143 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 A 3.60 BS02 MG A 1 D238 E239 D101 E102 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 B 3.60 BS02 08T B 1 S169 G170 G172 K173 E174 V175 E239 N280 L320 R357 S32 G33 G35 K36 E37 V38 E102 N143 L183 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 C 3.60 BS01 08T B 1 E256 D295 R299 E119 D158 R162 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 C 3.60 BS02 08T C 1 Y139 S169 G170 G172 K173 E174 E239 N280 L320 V356 R357 Y2 S32 G33 G35 K36 E37 E102 N143 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 D 3.60 BS01 08T C 1 E256 R299 E119 R162 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 D 3.60 BS02 08T D 1 E138 Y139 V140 S169 G170 V171 G172 K173 E174 V175 D238 E239 N280 V356 R357 E1 Y2 V3 S32 G33 V34 G35 K36 E37 V38 D101 E102 N143 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 E 3.60 BS01 08T E 1 Y139 S169 G170 G172 K173 E174 V175 E239 N280 R313 V356 R357 Y2 S32 G33 G35 K36 E37 V38 E102 N143 R176 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 F 3.60 BS01 08T E 1 L252 E256 D295 R299 L115 E119 D158 R162 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 G 3.60 BS01 08T G 1 Y139 S169 G170 G172 K173 E174 V175 D238 E239 L320 V356 R357 Y2 S32 G33 G35 K36 E37 V38 D101 E102 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 H 3.60 BS02 08T H 1 G170 G172 K173 E174 V175 D238 E239 N280 R313 L320 V356 R357 G33 G35 K36 E37 V38 D101 E102 N143 R176 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 I 3.60 BS02 08T I 1 Y139 S169 G170 G172 K173 E174 N280 V356 R357 Y2 S32 G33 G35 K36 E37 N143 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 J 3.60 BS02 08T J 1 Y139 V140 S169 G170 V171 G172 K173 E174 V175 E239 N280 L320 V356 R357 Y2 V3 S32 G33 V34 G35 K36 E37 V38 E102 N143 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 L 3.60 BS02 ADP L 1 E138 Y139 V140 G170 V171 G172 K173 E174 V175 D238 N280 L320 V356 R357 E1 Y2 V3 G33 V34 G35 K36 E37 V38 D101 N143 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 M 3.60 BS01 08T M 1 Y139 S169 G170 G172 K173 E174 D238 E239 N280 V356 R357 K360 Y2 S32 G33 G35 K36 E37 D101 E102 N143 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 N 3.60 BS01 08T N 1 S169 G170 G172 K173 E174 V175 D238 E239 N280 L320 F324 V356 R357 S32 G33 G35 K36 E37 V38 D101 E102 N143 L183 F187 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 O 3.60 BS01 08T N 1 L252 E256 R299 L115 E119 R162 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 O 3.60 BS02 08T O 1 S169 G170 V171 G172 K173 E174 V175 D238 E239 N280 L320 F324 V356 R357 K360 S32 G33 V34 G35 K36 E37 V38 D101 E102 N143 L183 F187 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 S 3.60 BS01 08T S 1 Y139 V140 F141 S169 G170 V171 G172 K173 E174 V175 D238 E239 N280 L320 F324 V356 R357 K360 Y2 V3 F4 S32 G33 V34 G35 K36 E37 V38 D101 E102 N143 L183 F187 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 T 3.60 BS01 08T T 1 E168 S169 G170 G172 K173 E174 V175 R313 L320 V356 R357 E31 S32 G33 G35 K36 E37 V38 R176 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 U 3.60 BS02 08T U 1 S169 G170 V171 G172 K173 E174 N280 R313 L320 V356 R357 S32 G33 V34 G35 K36 E37 N143 R176 L183 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 U 3.60 BS03 MG U 1 K173 N280 K36 N143 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4ly6 V 3.60 BS02 08T V 1 Y139 S169 G170 V171 G172 K173 E174 V175 E239 N280 F324 V356 R357 Y2 S32 G33 V34 G35 K36 E37 V38 E102 N143 F187 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lz5 A 1.50 BS02 1YV C 1 I481 P494 F495 M496 S497 K730 G731 N754 L759 I89 P102 F103 M104 S105 K215 G216 N239 L244 P19491 24215237 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lz5 B 1.50 BS04 1YV B 1 I481 P494 F495 M496 S497 S729 K730 G731 N754 L759 I88 P101 F102 M103 S104 S213 K214 G215 N238 L243 P19491 24215237 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lz5 C 1.50 BS03 1YV C 1 K493 P494 M496 S497 K730 L751 N754 K100 P101 M103 S104 K214 L235 N238 P19491 24215237 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lz7 A 2.10 BS03 1YW C 1 P494 M496 S497 S729 K730 N754 P102 M104 S105 S214 K215 N239 P19491 24215237 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lz7 C 2.10 BS03 1YW C 1 P494 F495 M496 S729 K730 N754 P101 F102 M103 S213 K214 N238 P19491 24215237 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lz8 A 1.85 BS02 1YX A 1 K493 P494 F495 M496 S497 S729 K730 V750 L751 N754 K101 P102 F103 M104 S105 S214 K215 V235 L236 N239 P19491 24215237 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lz8 C 1.85 BS01 1YX A 1 P494 F495 M496 S497 S729 K730 L751 P101 F102 M103 S104 S213 K214 L235 P19491 24215237 TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC 4lzz A 3.21 BS01 08T A 1 Y139 M146 S169 G170 G172 K173 E174 E239 N280 V356 R357 Y2 M9 S32 G33 G35 K36 E37 E102 N143 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz B 3.21 BS01 08T B 1 S169 G170 V171 G172 K173 E174 V175 E239 N280 V356 R357 S32 G33 V34 G35 K36 E37 V38 E102 N143 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz C 3.21 BS01 08T B 1 L252 D295 R299 L115 D158 R162 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz C 3.21 BS02 08T C 1 V140 F141 S169 G170 V171 G172 K173 E174 E239 V356 R357 K360 V3 F4 S32 G33 V34 G35 K36 E37 E102 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz D 3.21 BS01 08T D 1 Y139 V140 S169 G170 G172 K173 E174 V175 V356 R357 Y2 V3 S32 G33 G35 K36 E37 V38 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz F 3.21 BS01 ADP F 1 Y139 V140 S169 G170 V171 G172 K173 E174 V175 D238 E239 L320 F324 V356 R357 Y2 V3 S32 G33 V34 G35 K36 E37 V38 D101 E102 L183 F187 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz G 3.21 BS01 08T G 1 V140 M146 S169 G170 V171 G172 K173 E174 V175 D238 V356 R357 V3 M9 S32 G33 V34 G35 K36 E37 V38 D101 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz G 3.21 BS02 MG G 1 S169 D238 S32 D101 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz I 3.21 BS02 08T I 1 V140 S169 G170 G172 K173 E174 V175 E239 F324 V356 R357 V4 S33 G34 G36 K37 E38 V39 E103 F188 V220 R221 O67198 24240239 EEYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz K 3.21 BS02 08T K 1 Y139 V140 F141 S169 G170 V171 G172 K173 E174 V175 F324 V356 R357 K360 Y2 V3 F4 S32 G33 V34 G35 K36 E37 V38 F187 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz K 3.21 BS03 MG K 1 K173 E239 R357 K36 E102 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz L 3.21 BS02 ADP L 1 Y139 V140 F141 E168 S169 G170 V171 G172 K173 E174 V175 D238 L320 F324 V356 R357 K360 Y1 V2 F3 E30 S31 G32 V33 G34 K35 E36 V37 D100 L182 F186 V218 R219 K222 O67198 24240239 YVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz M 3.21 BS01 08T M 1 Y139 S169 G170 G172 K173 E174 V175 D238 E239 N280 F324 V356 R357 K360 Y2 S32 G33 G35 K36 E37 V38 D101 E102 N143 F187 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz Q 3.21 BS02 08T Q 1 Y139 S169 G170 V171 G172 K173 E174 E239 V356 R357 Y2 S32 G33 V34 G35 K36 E37 E102 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz S 3.21 BS01 08T S 1 Y139 V140 S169 G170 V171 G172 K173 E174 E239 N280 F324 V356 R357 K360 Y2 V3 S32 G33 V34 G35 K36 E37 E102 N143 F187 V219 R220 K223 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz T 3.21 BS02 08T T 1 Y139 S169 G170 V171 G172 K173 E174 V175 D238 E239 N280 V356 R357 Y2 S32 G33 V34 G35 K36 E37 V38 D101 E102 N143 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz U 3.21 BS01 08T T 1 L252 R299 L115 R162 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz V 3.21 BS02 08T V 1 Y139 V140 S169 G170 G172 K173 E174 V175 D238 E239 V356 R357 Y2 V3 S32 G33 G35 K36 E37 V38 D101 E102 V219 R220 O67198 24240239 EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLV 4lzz W 3.21 BS02 08T W 1 Y139 V140 F141 S169 G172 K173 E174 E239 N280 V356 R357 Y4 V5 F6 S34 G37 K38 E39 E104 N145 V221 R222 O67198 24240239 EEEYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELSCLVN 4m17 D 2.10 BS03 CA D 3 D297 E301 D330 D82 E86 D115 P35247 24224757 GQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDAGGSEDCVEIFTNGKWNDVACGEKRLVVCEF 4m18 A 3.20 BS04 CA A 4 E232 K246 E19 K33 P35247 24224757 LQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDAGGSEDCVEIFTNGKWNDVACGEKRLVVCEF 4mbx A 1.92 BS01 CA E 1 S214 E217 S190 E193 24204265 SHMGGVEVLEVRTGPDAITQIEAYLNPRMGNNIPSEDLYGYSNSINTAFSKASDTPNKDTLPCYSVAVIKLPLLNEDMTCDTILMWEAVSVKTEVVGISSLVNLHQGGKYIYGSSSGCVPVQGTTYHMFAVGGEPLELQGLVASSTATYPDDVVAIKNMKPGNQGLDPKAKALLDKDGKYPVEVWCPDPSKNENTRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDKLFLSCADIAGVHTNYSETQVWRGLPRYFNVTLRKRIVKNPYP 4mby A 1.48 BS01 SIA A 1 L62 Y65 Q130 G131 H271 N273 Y274 V279 L38 Y41 Q106 G107 H247 N249 Y250 V255 24204265 SHMGGVEVLEVRTGPDAITQIEAYLNPRMGNNIPSEDLYGYSNSINTAFSKASDTPNKDTLPCYSVAVIKLPLLNEDMTCDTILMWEAVSVKTEVVGISSLVNLHQGGKYIYGSSSGCVPVQGTTYHMFAVGGEPLELQGLVASSTATYPDDVVAIKNMKPGNQGLDPKAKALLDKDGKYPVEVWCPDPSKNENTRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDKLFLSCADIAGVHTNYSETQVWRGLPRYFNVTLRKRIVKNPYP 4mby A 1.48 BS03 GAL E 1 S74 K75 S50 K51 24204265 SHMGGVEVLEVRTGPDAITQIEAYLNPRMGNNIPSEDLYGYSNSINTAFSKASDTPNKDTLPCYSVAVIKLPLLNEDMTCDTILMWEAVSVKTEVVGISSLVNLHQGGKYIYGSSSGCVPVQGTTYHMFAVGGEPLELQGLVASSTATYPDDVVAIKNMKPGNQGLDPKAKALLDKDGKYPVEVWCPDPSKNENTRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDKLFLSCADIAGVHTNYSETQVWRGLPRYFNVTLRKRIVKNPYP 4mby H 1.48 BS03 SIA H 1 L62 Y65 Q130 G131 H271 N273 Y274 L38 Y41 Q105 G106 H246 N248 Y249 24204265 SHMGGVEVLEVRTGPDAITQIEAYLNPRMGNNIPSEDLYGYSNSINTAFSKASDTPNKDTLPCYSVAVIKLPLLNEDMTCTILMWEAVSVKTEVVGISSLVNLHQGGKYIYGSSSGCVPVQGTTYHMFAVGGEPLELQGLVASSTATYPDDVVAIKNMKPGNQGLDPKAKALLDKDGKYPVEVWCPDPSKNENTRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDKLFLSCADIAGVHTNYSETQVWRGLPRYFNVTLRKRIVKN 4mby I 1.48 BS02 GAL H 1 F73 S74 K75 F49 S50 K51 24204265 SHMGGVEVLEVRTGPDAITQIEAYLNPRMGNNIPSEDLYGYSNSINTAFSKASDTPNKDTLPCYSVAVIKLPLLNEDMCDTILMWEAVSVKTEVVGISSLVNLHQGGKYIYGSSSGCVPVQGTTYHMFAVGGEPLELQGLVASSTATYPDDVVAIKNMKPGNQGLDPKAKALLDKDGKYPVEVWCPDPSKNENTRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDKLFLSCADIAGVHTNYSETQVWRGLPRYFNVTLRKRIVKN 4mbz B 1.75 BS03 SIA B 1 L62 Y65 S68 Q130 G131 H271 N273 Y274 V279 L37 Y40 S43 Q105 G106 H246 N248 Y249 V254 24204265 SHMGGVEVLEVRGPDAITQIEAYLNPRMGNNIPSEDLYGYSNSINTAFSKASDTPNKDTLPCYSVAVIKLPLLNEDMTCDTILMWEAVSVKTEVVGISSLVNLHQGGKYIYGSSSGCVPVQGTTYHMFAVGGEPLELQGLVASSTATYPDDVVAIKNMKPGNQGLDPKAKALLDKDGKYPVEVWCPDPSKNENTRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDKLFLSCADIAGVHTNYSETQVWRGLPRYFNVTLRKRIVKNP 4mcz A 2.41 BS01 III C 1 Q9 F24 I31 F51 A52 S53 F54 N62 Q7 F22 I29 F49 A50 S51 F52 N60 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4mcz A 2.41 BS02 III C 2 E11 N62 V65 D66 N69 I72 M73 E9 N60 V63 D64 N67 I70 M71 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4mcz B 2.41 BS01 III C 1 Y78 H81 N82 V85 G86 Y77 H80 N81 V84 G85 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 4mcz B 2.41 BS02 III C 3 H13 Y30 Y37 D57 Y60 W61 K71 H12 Y29 Y36 D56 Y59 W60 K70 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 4md0 A 2.19 BS01 III C 1 Q9 F24 I31 W43 A52 S53 F54 N62 Q7 F22 I29 W41 A50 S51 F52 N60 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4md0 A 2.19 BS02 III C 2 E11 N62 V65 D66 N69 E9 N60 V63 D64 N67 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4md0 B 2.19 BS02 III C 3 H13 Y30 Y60 W61 K71 H12 Y29 Y59 W60 K70 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 4md4 A 1.95 BS01 III C 1 I31 F32 A52 S53 F54 E55 I29 F30 A50 S51 F52 E53 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDTSG 4md4 A 1.95 BS02 VAL C 1 Q9 N62 Q7 N60 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDTSG 4md4 A 1.95 BS03 III C 2 E11 N62 V65 D66 N69 I72 R76 E9 N60 V63 D64 N67 I70 R74 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDTSG 4md4 B 1.95 BS01 III C 1 H81 N82 V85 G86 H80 N81 V84 G85 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 4md4 B 1.95 BS02 III C 3 V11 H13 Y30 Y47 P56 D57 Y60 W61 K71 V10 H12 Y29 Y46 P55 D56 Y59 W60 K70 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 4md5 A 1.65 BS01 III C 1 Q9 F24 A52 S53 F54 G58 N62 Q7 F22 A50 S51 F52 G56 N60 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDT 4md5 B 1.65 BS02 III C 3 H13 Y30 P56 D57 Y60 W61 L67 R71 H12 Y29 P55 D56 Y59 W60 L66 R70 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVVESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRAT 4mdi A 2.00 BS01 III C 1 Q9 F24 F51 A52 S53 F54 G58 N62 Q7 F22 F49 A50 S51 F52 G56 N60 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4mdi B 2.00 BS02 III C 3 H13 Y30 P56 D57 Y60 W61 I67 H12 Y29 P55 D56 Y59 W60 I66 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDILEDERAAVDTYCRHNYGVVESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA 4mdj A 1.70 BS01 III C 1 Q9 E11 F24 A52 S53 F54 G58 N62 V65 D66 N69 I72 R76 Q7 E9 F22 A50 S51 F52 G56 N60 V63 D64 N67 I70 R74 P01903 24190431 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4mdj B 1.70 BS01 III C 1 H13 F26 Y30 Y47 P56 D57 Y60 W61 D70 E71 T77 Y78 H81 N82 V85 H12 F25 Y29 Y46 P55 D56 Y59 W60 D69 E70 T76 Y77 H80 N81 V84 P13760 24190431 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDILEDERAAVDTYCRHNYGVVESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRATG 4mgv A 1.72 BS01 D5I A 1 Y43 D55 F64 V73 I74 W77 Y100 F117 Y39 D51 F60 V69 I70 W73 Y96 F113 5.2.1.8 A5K8X6 TLEQVHLTEDGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVPFKFHLGQGEVIKGWDICVASMTKNEKCSVRLDSKYGYGEEGCGESIPGNSVLIFEIELISFRE 4mkm A 1.75 BS01 CA A 1 D118 D120 N122 E124 D126 D113 D115 N117 E119 D121 B1R775 EGTLKTTVAADGVNGSSEKEALVSFENSKDGVDVKDTIDYKDLVANEKYNLTGKLMHVKDDGSLEEVATKTTEVTAVENGSGQWELDFGNQKLQVGEKYVVFENAESVENLIDTDNNYELDTKQVVKHEDKNDKAQTLIVEKPNLPEVKDGTLRTTVIADGVNGSSEKEALVSFENSKDGVDVKDTINYEGLVANQNYTLTGTLMHVKADGSLEEIATKTTNVTAGENGNGTWGLDFGNQKLQVGEKYVVFENAESVENLIDTDKDYNLDTKQVVKHEDKNDKAQTLVVEKP 4mkm A 1.75 BS02 CA A 2 D165 N181 D184 G185 V186 D160 N176 D179 G180 V181 B1R775 EGTLKTTVAADGVNGSSEKEALVSFENSKDGVDVKDTIDYKDLVANEKYNLTGKLMHVKDDGSLEEVATKTTEVTAVENGSGQWELDFGNQKLQVGEKYVVFENAESVENLIDTDNNYELDTKQVVKHEDKNDKAQTLIVEKPNLPEVKDGTLRTTVIADGVNGSSEKEALVSFENSKDGVDVKDTINYEGLVANQNYTLTGTLMHVKADGSLEEIATKTTNVTAGENGNGTWGLDFGNQKLQVGEKYVVFENAESVENLIDTDKDYNLDTKQVVKHEDKNDKAQTLVVEKP 4mkm A 1.75 BS04 CA A 4 D267 D269 D271 N273 D275 D262 D264 D266 N268 D270 B1R775 EGTLKTTVAADGVNGSSEKEALVSFENSKDGVDVKDTIDYKDLVANEKYNLTGKLMHVKDDGSLEEVATKTTEVTAVENGSGQWELDFGNQKLQVGEKYVVFENAESVENLIDTDNNYELDTKQVVKHEDKNDKAQTLIVEKPNLPEVKDGTLRTTVIADGVNGSSEKEALVSFENSKDGVDVKDTINYEGLVANQNYTLTGTLMHVKADGSLEEIATKTTNVTAGENGNGTWGLDFGNQKLQVGEKYVVFENAESVENLIDTDKDYNLDTKQVVKHEDKNDKAQTLVVEKP 4mn8 A 3.06 BS01 III C 1 Y128 Y148 D150 R152 G174 M196 V198 D220 Q268 E270 Y272 R294 Y296 H316 S320 E321 V340 T342 H344 T366 H392 D393 L412 D414 S416 H417 S437 Q485 Y103 Y123 D125 R127 G149 M171 V173 D195 Q243 E245 Y247 R269 Y271 H291 S295 E296 V315 T317 H319 T341 H367 D368 L387 D389 S391 H392 S412 Q460 2.7.11.1 Q9FL28 24114786 SFEPEIEALKSFKNGISNDPLGVLSDWTIIGSLRHCNWTGITCDSTGHVVSVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPAEIGKLTELNQLILYLNYFSGSIPSGIWELKNIFYLDLRNNLLSGDVPEEICKTSSLVLIGFDYNNLTGKIPECLGDLVHLQMFVAAGNHLTGSIPVSIGTLANLTDLDLSGNQLTGKIPRDFGNLLNLQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRLTQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGELPADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIPRGFGRMNLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLIGKLQKLRILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSNLTLLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLESLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKNMQLYLNFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNVFTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLVSLDLSSNNLTGEIPESLANLSTLKHLKLASNNLKGHVPESGVFKNINASDLMGNTDLCG 4mn8 B 3.06 BS01 III C 1 T52 L53 V54 T27 L28 V29 2.7.10.1,2.7.11.1 Q94F62 24114786 NAEGDALSALKNSLADPNKVLQSWDATLVTPCTWFHVTCNSDNSVTRVDLGNANLSGQLVMQLGQLPNLQYLELYSNNITGTIPEQLGNLTELVSLDLYLNNLSGPIPSTLGRLKKLRFLRLNNNSLSGEIPRSLTAVLTLQVLDLSNNPLTGDIPVNGSFSLFTPISFANTKLT 4mwi A 1.70 BS01 PXN A 1 S202 W206 Y218 S10 W14 Y26 Q8NB16 24219132 IKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFS 4mxo A 2.10 BS01 DB8 A 1 L273 A293 I294 K295 E310 M314 V323 I336 T338 E339 Y340 M341 S342 G344 L393 D404 L17 A37 I38 K39 E54 M58 V67 I80 T82 E83 Y84 M85 S86 G88 L137 D148 2.7.10.2 P12931 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mxo B 2.10 BS01 DB8 B 1 L273 V281 A293 I294 K295 E310 V323 I336 T338 E339 Y340 M341 S342 G344 L393 D404 L16 V24 A36 I37 K38 E53 V66 I79 T81 E82 Y83 M84 S85 G87 L136 D147 2.7.10.2 P12931 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mxx A 2.60 BS01 DB8 A 1 L273 A293 I294 K295 E310 M314 V323 I336 T338 E339 Y340 M341 S342 K343 G344 L393 T403 L17 A37 I38 K39 E54 M58 V67 I80 T82 E83 Y84 M85 S86 K87 G88 L137 T147 2.7.10.2 P12931 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVTDFGLARLIEFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mxx B 2.60 BS01 DB8 B 1 L273 A293 I294 K295 V323 I336 T338 E339 Y340 M341 S342 G344 L393 T403 F405 L16 A36 I37 K38 V66 I79 T81 E82 Y83 M84 S85 G87 L136 T146 F148 2.7.10.2 P12931 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVTDFGLFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mxz A 2.58 BS01 DB8 A 1 L273 V281 A293 K295 E310 V323 I336 M338 E339 Y340 M341 S342 G344 L393 D404 L17 V25 A37 K39 E54 V67 I80 M82 E83 Y84 M85 S86 G88 L137 D148 2.7.10.2 P12931 KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVLKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4mxz B 2.58 BS01 DB8 B 1 L273 A293 I294 K295 E310 V323 I336 M338 E339 Y340 M341 G344 L393 A403 D404 L16 A36 I37 K38 E53 V66 I79 M81 E82 Y83 M84 G87 L136 A146 D147 2.7.10.2 P12931 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVLKKLRHEKLVQLYAVVSEEPIYIVMEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4naq A 2.10 BS01 III B 1 Q208 A348 M349 E350 V380 H383 Q384 E406 S410 E413 P432 G433 D434 R437 Y472 Q145 A285 M286 E287 V317 H320 Q321 E343 S347 E350 P369 G370 D371 R374 Y409 3.4.11.2 P15145 23071329 SKPWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRFLCQEPTDVIIIHSKKLNYTTQGHMVVLRGVGDSQVPEIDRTELVELTEYLVVHLKGSLQPGHMYEMESEFQGELADDLAGFYRSEYMEGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRENALLFDPQSSSISNKERVVTVIAHQLAHQWFGNLVTLAWWNDLWLNEGFASYVEYLGADHAEPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKGASVIRMLSNFLTEDLFKEGLASYLHAFAYQNTTYLDLWEHLQKAVDAQTSIRLPDTVRAIMDRWTLQMGFPVITVDTKTGNISQKHFLLDSESNVTRSSAFDYLWIVPISSIKNGVMQDHYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQVNYDEDNWRMIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKEYMPWQAALSSLSYFSLMFDRSEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQYSEINAISTACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDFAWGQLQQAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVIGQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFGSGTRALEQALEKTKANIKWVKENKEVVLNWFIEHSS 4nbt A 1.48 BS01 NAD A 1 G13 A15 K16 G17 L18 D37 L38 L53 N54 V55 T56 N81 A82 G83 I84 I131 S132 S133 Y146 K150 P178 G179 Y180 I181 T183 G12 A14 K15 G16 L17 D36 L37 L52 N53 V54 T55 N80 A81 G82 I83 I130 S131 S132 Y145 K149 P177 G178 Y179 I180 T182 1.1.1.100 A9NFJ2 24212572 KKLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIMTDILKTVPQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTINVNGGMRL 4nbu A 1.34 BS01 NAI A 1 G20 N23 G24 I25 D44 F45 V65 D66 V67 N93 A94 G95 I96 V116 T143 S144 S145 Y158 K162 P188 G189 F190 T191 T193 M195 V196 G12 N15 G16 I17 D36 F37 V57 D58 V59 N85 A86 G87 I88 V108 T135 S136 S137 Y150 K154 P180 G181 F182 T183 T185 M187 V188 A6CQL2 24212572 SRLQDKVAIITGAANGIGLEAARVFMKEGAKVVIADFNEAAGKEAVEANPGVVFIRVDVSDRESVHRLVENVAERFGKIDILINNAGITRDSMLSKMTVDQFQQVINVNLTGVFHCTQAVLPYMAEQGKGKIINTSSVTGTYGNVGQTNYAAAKAGVIGMTKTWAKELARKGINVNAVAPGFTETAMVAEVPEKVIEKMKAQVPMGRLGKPEDIANAYLFLASHESDYVNGHVLHVDGGIMM 4nbu B 1.34 BS02 CAA B 1 T97 D99 K104 S145 T147 N152 V153 G154 Q155 Y158 F190 M195 V196 K206 T91 D93 K98 S139 T141 N146 V147 G148 Q149 Y152 F184 M189 V190 K200 A6CQL2 24212572 HMSRLQDKVAIITGAANGIGLEAARVFMKEGAKVVIADFNEAAGKEAVEANPGVVFIRVDVSDRESVHRLVENVAERFGKIDILINNAGITRDSMLSKMTVDQFQQVINVNLTGVFHCTQAVLPYMAEQGKGKIINTSSVTGTYGNVGQTNYAAAKAGVIGMTKTWAKELARKGINVNAVAPGFTETAMVAEVPEKVIEKMKAQVPMGRLGKPEDIANAYLFLASHESDYVNGHVLHVDGGIMM 4nbw A 2.00 BS01 NAD A 1 G19 A21 N22 G23 I24 D43 L44 V68 D69 V70 N96 A97 G98 V128 N129 S156 S157 Y170 K174 P200 G201 I203 T205 G8 A10 N11 G12 I13 D32 L33 V57 D58 V59 N85 A86 G87 V117 N118 S145 S146 Y159 K163 P189 G190 I192 T194 A6G411 24212572 KRVAIITGAANGIGRATALEFAQAGYHVVAWDLAEEAGAALIAEIADAGGSADFARVDVSAAESVEAAVAEIIAEHGRVDVLVNNAGILHDGQLVKVKGGEVVKKMAEAQFDAVISVNLKGVFLCTQAVAPHMIAAKYGRILNASSVVGLYGNFGQTNYVAAKSGVIGMTKVWARELGRYGITVNAIAPGFIATEMVQQMPERVLEAMVARTPVGRIGDPVDIARAYLFLASEESGFISGTTLSVDGGMVVGS 4nbw B 2.00 BS01 NAD B 1 G19 A21 N22 G23 I24 D43 L44 V68 D69 V70 N96 A97 G98 I99 V128 A155 S156 S157 Y170 K174 P200 G201 I203 T205 M207 G8 A10 N11 G12 I13 D32 L33 V57 D58 V59 N85 A86 G87 I88 V117 A144 S145 S146 Y159 K163 P189 G190 I192 T194 M196 A6G411 24212572 KRVAIITGAANGIGRATALEFAQAGYHVVAWDLAEEAGAALIAEIADAGGSADFARVDVSAAESVEAAVAEIIAEHGRVDVLVNNAGILHDGQLVKVKGGEVVKKMAEAQFDAVISVNLKGVFLCTQAVAPHMIAAKYGRILNASSVVGLYGNFGQTNYVAAKSGVIGMTKVWARELGRYGITVNAIAPGFIATEMVQQMPERVLEAMVARTPVGRIGDPVDIARAYLFLASEESGFISGTTLSVDGGMVVGS 4nel A 2.05 BS01 KEN A 1 Q180 W198 W218 D252 Q86 W104 W124 D158 C7MT25 SEARRRILETAWRLIARRGYHNVRIHDIASELGTSNATIHYHFPSKKDILLEALRRNVKLAFDRQVAELHTIADARERLVRLVELQLPTPGLLRDEWSVWLQVWTESTLNPKIRDLYNDAYDRWYQTIAMTIRTGQKQGVFRDQDADELATRLSALIDGLGIQVLTGKRGCSVDHMRQHLNDFIEHNIVE 4ngu A 2.50 BS01 DAL A 1 S99 E156 I160 M182 N219 S244 D245 Q246 S71 E128 I132 M154 N191 S216 D217 Q218 Q311Q1 MAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGNEQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIAFTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANVQYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKWLSGQIDTAWIDHAMEDARKANEAV 4ngu A 2.50 BS02 DAL A 2 N40 R180 M182 W202 N219 Y223 N12 R152 M154 W174 N191 Y195 Q311Q1 MAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGNEQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIAFTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANVQYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKWLSGQIDTAWIDHAMEDARKANEAV 4nml A 2.60 BS01 MLT A 1 K8 T32 T33 G89 D91 K129 K8 T32 T33 G89 D91 K129 5.3.1.6 S8GQK2 MNPQDKAKQAVGYFAVDTYVRSGMKVGLGTGTTAKFVVERIGQRMQEGSLKDLLCVPTSEATRKQAESLGIPLTTLDGIADCLDVAIDGADEILPPTLGLVKGRGGALLREKMIAAAAKTFIVAADETKLVSNGIGSTGALPVEVVVFSGSHTKRLLSALPSVKRHGGRAEFRKRAGAAQEDIREEDRFVTDNGNYIVDLYFTETVPDLHEMDKELKSIPGVVETGFFLDLASVCLIGKADGSVATLTAE 4nmx B 1.85 BS01 III Z 1 P155 D238 A239 I369 D374 T377 C378 F379 P3 D70 A71 I201 D206 T209 C210 F211 3.4.21.- Q8NBP7 24225950 SIPWNLERITPGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFSKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPP 4nmy A 1.90 BS01 VIB A 1 W12 N15 Y62 E64 S90 W114 W158 I159 F160 W163 Y189 T191 W10 N13 Y60 E62 S88 W112 W156 I157 F158 W161 Y187 T189 Q187U0 SKKVTMVLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQVTYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFKAVMKKNRADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKDLDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEVDEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEFLPQ 4nn3 A 1.40 BS01 ORO A 1 L36 E37 R43 F96 R172 M174 F195 N212 T216 M237 L9 E10 R16 F69 R145 M147 F168 N185 T189 M210 C6BW16 KYEARIGHLESPLQPRHQGLEKVAKLVKERTNGEVEFKIFPSSQLGNQRQMNEGVQFGTIEGTVSAAAFLGGFNPVVSIMDIPFLLPVDRAKAQELRQGKFGKALLKSFDSRGFKAIATWPNGRKNFTSNKPISTIADYKGQSFRVMDSKILIEQFAAIGASAIALPFGELYTALQNGVVDGEENPLDTIQRMKFYEVQKYLVTSEHGAMEDYVLFNPSYWESLPENYQKIIVDTFIEVMPGVEAHKEQAQKDALEVIKKAGVQVTPLQAADRAAMRELMYPKTKAAYLARAGAQGQELIKLYEEEYARIV 4nog A 1.20 BS01 PLP A 1 G136 A137 Y171 W172 E224 D257 I259 Q260 K286 G119 A120 Y154 W155 E207 D240 I242 Q243 K269 2.6.1.13 S8EY38 RKTNIEAYRDGLKLKTEEDFFACDRQYVCQNYAPVPVVISKGKGARVWDINGNEYYDFLAGVSSLSQGHCHPRVIAALCRQAERLTLTLRAFGNDVTGPACRFMAEMFGYDRVLLMNTGAEAGESALKIARKWAYEVKEIPPDSAKVILCNNNYWGRTITACSSSTTFDCYNNFGPFTPGFELIDYDDVGALEEALKDPNVAAFFVEPIQGEGGVNVPKPGYLKRAHELCRSKNVLLIVDEIQTGLCRTGRLLAADHDEVHPDILLLGKSLSAGVVPISAVMGRADVMDVLKPGTHGSTFGGNPLACAVAVEALTVLKDEKLADRAERLGAQFRDCLRRELYGKVPWIKEIRGRGLLNAVEVDSDAIDPNDVVMKLKENGILSKPTRGRVMRFIPPLVITDEEHRDATTRIIKSFLAVEEER