2m32 A BS01 III B 1 N14 S15 I16 Y17 P18 D114 G115 E116 R148 F156 N14 S15 I16 Y17 P18 D114 G115 E116 R148 F156 P56199 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERI 2m32 A BS02 III C 1 S13 N14 S15 R79 Q80 T81 S117 H118 F156 S13 N14 S15 R79 Q80 T81 S117 H118 F156 P56199 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERI 2m32 A BS03 MG A 1 S13 S15 T81 S13 S15 T81 P56199 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERI 2mf8 A BS01 NUC B 1 H812 I813 T814 Y817 S819 R821 S822 L823 S824 G825 S841 A842 S866 L867 H14 I15 T16 Y19 S21 R23 S24 L25 S26 G27 S43 A44 S68 L69 Q8CFC2 24097990 LLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRA 2mf8 A BS02 NUC C 1 L800 R821 S822 L823 H856 I857 T858 Y861 S863 R865 S866 S868 G869 L2 R23 S24 L25 H58 I59 T60 Y63 S65 R67 S68 S70 G71 Q8CFC2 24097990 LLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRA 2mf8 A BS03 ZN A 1 C802 C807 H820 C826 C4 C9 H22 C28 Q8CFC2 24097990 LLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRA 2mf8 A BS04 ZN A 2 C846 T848 C851 H864 C870 C48 T50 C53 H66 C72 Q8CFC2 24097990 LLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRA 2yoc A 2.88 BS01 CA A 1 S376 D469 L470 E475 E556 S357 D450 L451 E456 E537 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSS 2yoc A 2.88 BS02 CA A 2 T472 A538 D541 Y543 D881 T453 A519 D522 Y524 D862 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSS 2yoc A 2.88 BS03 CA A 3 D982 S989 D991 L994 D995 Q1058 D963 S970 D972 L975 D976 Q1039 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSS 2yoc A 2.88 BS04 CA A 4 E621 E627 D702 R703 E602 E608 D683 R684 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSS 2yoc B 2.88 BS01 CA B 1 S376 D469 L470 E475 E556 S357 D450 L451 E456 E537 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSSYYHH 2yoc B 2.88 BS02 CA B 2 T472 A538 D541 Y543 D881 T453 A519 D522 Y524 D862 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSSYYHH 2yoc B 2.88 BS03 CA B 3 D982 S989 D991 L994 Q1058 D963 S970 D972 L975 Q1039 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSSYYHH 2yoc B 2.88 BS04 CA B 4 E621 Q700 D702 R703 E602 Q681 D683 R684 3.2.1.41 G8WM45 DVVVRLPDVAVPGEAVTAVENQAVIHLVDIAGITSSSAADYSSKNLYLWNNETCDALSAPVADWNDVSTTPSGSDKYGPYWVIPLNKESGCINVIVRDGTDKLIDSDLRVAFGDFTDRTVSVIAGNSAVYDSRADAFRAAFGVALAEAHWVDKNTLLWPGGQDKPIVRLYYSHSSKVAADGEGKFTDRYLKLTPTTVSQQVSMRFPHLSSYAAFKLPDNANVDELLQGETVAIAAAEDGILISATQVQTAGVLDDAYAEAAEALSYGAQLADGGVTFRVWAPTAQQVDVVVYSADKKVIGSHPMTRDSASGAWSWQGGSDLKGAFYRYAMTVYHPQSRKVEQYEVTDPYAHSLSTNSEYSQVVDLNDSALKPDGWDNLTMPHAQKTKADLAKMTIHESHIRDLSAWDQTVPAELRGKYLALTAGDSNMVQHLKTLSASGVTHVELLPVFDLATVNEFSDKVADIQQPFSRLCEVNSAVKSSEFAGYCDSGSTVEEVLNQLKQSDSQDNPQVQALNTLVAQTDSYNWGYDPFHYTVPEGSYATDPEGTTRIKEFRTMIQAIKQDLGMNVIMDVVYNHTNAAGPTDRTSVLDKIVPWYYQRLNETTGSVESATCCSDSAPEHRMFAKLIADSLAVWTTDYKIDGFRFDLMGYHPKAQILSAWERIKALNPDIYFFGEGWDSNQSDRFEIASQINLKGTGIGTFSDRLRDSVRGGGPFDSGDALRQNQGIGSGAGVLPNELASLSDDQVRHLADLTRLGMAGNLADFVMIDKDGAAKKGSEIDYNGAPGGYAADPTEVVNYVSKHDNQTLWDMISYKASQEADLATRVRMQAVSLATVMLGQGIAFDQQGSELLRSKSFTRDSYDSGDWFNRVDYSLQDNNYNVGMPRISDDGSNYEVITRVKEMVATPGEAELKQMTAFYQELTELRKSSPLFTLGDGSAVMKRVDFRNTGSDQQAGLLVMTVDDGMKAGASLDSRLDGLVVAINAAPESRTLNEFAGETLQLSAIQQTAGENSLANGVQIAADGTVTLPAWSVAVLELPQGEAQGAGLPVSSYYHH 2you A 2.19 BS01 III B 1 W30 G33 F34 D37 I51 Y52 Q54 F55 F64 F72 F85 T92 S93 A182 L183 S184 W23 G26 F27 D30 I44 Y45 Q47 F48 F57 F65 F78 T85 S86 A175 L176 S177 P62168 LKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2you A 2.19 BS02 III C 1 F55 F56 Y129 M131 V132 G133 V136 E137 P139 E142 S178 Q181 A182 Y186 D187 F48 F49 Y122 M124 V125 G126 V129 E130 P132 E135 S171 Q174 A175 Y179 D180 P62168 LKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2you A 2.19 BS03 CA A 1 D73 N75 D77 R79 E81 E84 D66 N68 D70 R72 E74 E77 P62168 LKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2you A 2.19 BS04 CA A 2 D109 D111 D113 Y115 E120 D102 D104 D106 Y108 E113 P62168 LKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2you A 2.19 BS05 CA A 3 D157 N159 D161 K163 E168 D150 N152 D154 K156 E161 P62168 LKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2yov A 1.95 BS01 CA A 1 D73 N75 D77 R79 E84 D66 N68 D70 R72 E77 P62168 GKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2yov A 1.95 BS02 CA A 2 D109 D111 D113 Y115 E120 D102 D104 D106 Y108 E113 P62168 GKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2yov A 1.95 BS03 CA A 3 D157 N159 D161 K163 E168 D143 N145 D147 K149 E154 P62168 GKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV 2yov B 1.95 BS01 CA B 1 D73 N75 D77 R79 E81 E84 D64 N66 D68 R70 E72 E75 P62168 PEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSL 2yov B 1.95 BS02 CA B 2 D109 D111 D113 Y115 E120 D100 D102 D104 Y106 E111 P62168 PEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSL 2yov B 1.95 BS03 CA B 3 D157 N159 D161 K163 E168 D143 N145 D147 K149 E154 P62168 PEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSL 3w0t A 1.35 BS01 ZN A 1 Q33 E99 Q26 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t A 1.35 BS02 HPU A 1 H126 M157 E172 M179 L182 M183 H119 M150 E165 M172 L175 M176 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t A 1.35 BS03 ZN B 1 H126 E172 H119 E165 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t A 1.35 BS04 HPU B 1 Q33 M35 C60 F62 F67 L69 F71 E99 T101 Q26 M28 C53 F55 F60 L62 F64 E92 T94 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t B 1.35 BS01 ZN A 1 H126 E172 H125 E171 4.4.1.5 Q04760 EPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t B 1.35 BS02 HPU A 1 Q33 M35 C60 F67 L69 F71 L92 E99 Q32 M34 C59 F66 L68 F70 L91 E98 4.4.1.5 Q04760 EPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t B 1.35 BS03 ZN B 1 Q33 E99 Q32 E98 4.4.1.5 Q04760 EPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t B 1.35 BS04 HPU B 1 H126 M157 F162 E172 M179 M183 H125 M156 F161 E171 M178 M182 4.4.1.5 Q04760 EPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t C 1.35 BS01 ZN C 1 Q33 E99 Q26 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t C 1.35 BS02 HPU C 1 H126 M157 E172 M179 L182 M183 H119 M150 E165 M172 L175 M176 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t C 1.35 BS03 ZN D 1 H126 E172 H119 E165 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t C 1.35 BS04 HPU D 1 Q33 M35 C60 F62 L69 F71 L92 E99 Q26 M28 C53 F55 L62 F64 L85 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t D 1.35 BS01 ZN C 1 H126 E172 H119 E165 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t D 1.35 BS02 HPU C 1 Q33 M35 C60 F62 F67 L69 F71 E99 Q26 M28 C53 F55 F60 L62 F64 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t D 1.35 BS03 ZN D 1 Q33 E99 Q26 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0t D 1.35 BS04 HPU D 1 H126 M157 L160 W170 E172 M179 M183 H119 M150 L153 W163 E165 M172 M176 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 3w0u A 1.70 BS01 ZN A 1 Q33 E99 Q26 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u A 1.70 BS02 ZN A 2 H126 E172 H119 E165 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u A 1.70 BS03 HPW A 1 H126 K150 K156 M157 L160 F162 E172 M179 H119 K143 K149 M150 L153 F155 E165 M172 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u A 1.70 BS04 HPW B 1 Q33 M35 C60 F62 F67 L69 I88 E99 Q26 M28 C53 F55 F60 L62 I81 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u B 1.70 BS01 ZN A 1 H126 E172 H119 E165 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u B 1.70 BS02 ZN A 3 Q33 E99 Q26 E92 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u B 1.70 BS03 HPW A 1 Q33 M35 C60 F67 L69 F71 E99 T101 Q26 M28 C53 F60 L62 F64 E92 T94 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0u B 1.70 BS04 HPW B 1 H126 M157 L160 E172 M179 A180 L182 H119 M150 L153 E165 M172 A173 L175 4.4.1.5 Q04760 GGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATL 3w0w A 2.60 BS01 III C 1 Y7 Y59 E62 E63 K66 H70 T73 N77 I80 Y84 L95 F99 Y116 Y123 T143 K146 W147 V152 Q155 Q156 Y159 Y171 Y7 Y59 E62 E63 K66 H70 T73 N77 I80 Y84 L95 F99 Y116 Y123 T143 K146 W147 V152 Q155 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWGSLGG 3w0w D 2.60 BS01 III C 1 Y92 Q94 G96 Y92 Q94 G96 QKEVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMSIYSNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLWGTYNQGGKLIFGQGTELSVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESS 3w0w E 2.60 BS01 III C 1 E30 Y31 M50 S94 A96 H98 E30 Y31 M50 S94 A96 H98 EAQVTQNPRYLITVTGKKLTVTCSQNMNHEYMSWYRQDPGLGLRQIYYSMNVEVTDKGDVPEGYKVSRKEKRNFPLILESPSPNQTSLYFCASSGASHEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3zka A 1.55 BS01 MN A 1 H139 E205 H108 E174 P0A4G2 KLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTNSIAEQGKEGDSYYSMMKYNLDKIAEGLAK 3zka B 1.55 BS01 MN B 1 H139 E205 H108 E174 P0A4G2 KLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTNSIAEQGKEGDSYYSMMKYNLDKIAEGLAK 3zps A 1.55 BS01 EQM B 1 R8 D25 G27 A28 D29 I47 G48 G49 I50 P81 R8 D25 G27 A28 D29 I47 G48 G49 I50 P81 3.4.23.16 P03366 24160253 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF 3zps B 1.55 BS01 EQM B 1 L123 D125 G127 A128 D129 G148 G149 I150 P181 L23 D25 G27 A28 D29 G48 G49 I50 P81 3.4.23.16 P03366 24160253 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF 3zpt A 1.54 BS01 M8Y B 1 R8 D25 G27 A28 D29 G48 G49 I50 P81 T82 R8 D25 G27 A28 D29 G48 G49 I50 P81 T82 3.4.23.16 P03366 24160253 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF 3zpt B 1.54 BS01 M8Y B 1 R108 L123 D125 G127 A128 D129 G148 G149 I150 P181 T182 R8 L23 D25 G27 A28 D29 G48 G49 I50 P81 T82 3.4.23.16 P03366 24160253 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF 3zpu A 1.80 BS01 M8B B 1 R8 D25 G27 A28 D29 D30 I47 G48 G49 I50 P81 T82 R8 D25 G27 A28 D29 D30 I47 G48 G49 I50 P81 T82 3.4.23.16 P03366 24160253 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF 3zpu B 1.80 BS01 M8B B 1 R108 L123 D125 G127 A128 D129 G148 G149 I150 P181 T182 R8 L23 D25 G27 A28 D29 G48 G49 I50 P81 T82 3.4.23.16 P03366 24160253 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICGHKAIGTVLVGPTPTNVIGRNLLTQIGCTLNF 4bf9 A 2.60 BS01 FMN A 1 A6 P7 M8 E9 V11 F33 Q68 N95 C98 K139 H168 Y176 N200 G201 E202 G224 R225 A9 P10 M11 E12 V14 F36 Q71 N98 C101 K142 H171 Y179 N203 G204 E205 G227 R228 1.3.1.- P33371 MASMRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKTVNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL 4bfa A 1.65 BS01 FMN A 1 A6 P7 M8 E9 V11 F33 Q68 N95 C98 K139 H168 Y176 N200 G201 E202 G224 R225 A8 P9 M10 E11 V13 F35 Q70 N97 C100 K141 H170 Y178 N202 G203 E204 G226 R227 1.3.1.- P33371 ASMRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKTVNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL 4bfa B 1.65 BS01 FMN B 1 A6 P7 M8 E9 V11 F33 Q68 N95 K139 H168 Y176 N200 G201 E202 G224 R225 A8 P9 M10 E11 V13 F35 Q70 N97 K131 H160 Y168 N192 G193 E194 G216 R217 1.3.1.- P33371 ASMRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL 4bqn A 1.38 BS01 COA A 1 S13 C14 Q15 V68 S69 Y72 Y97 H99 W159 E163 R167 N172 N200 R294 S13 C14 Q15 V68 S69 Y72 Y97 H99 W159 E163 R167 N172 N200 R294 Q63R74 SMAQRKKYSVYGSCQAPALAKMLNSCPTFARDWELVEMEPCFVASEEQIDRHLAETIPKLDLFLYQPVSEGYRGEKYSSVFLRNSMPPGGNALSVQYMHWEGYHPTVNSPYGLPPHPEGYVDALIAGAVVMDVDKETYLRHLEEIGASLRIDIDEIESWCVDELKTREVGENDGGKQIDISVTDFILANCRQKRLFYTMNHPTAALMREIAARCMLALGYTYSDISFDQNLDPLDVTKMSLYPIYRDCFDFSELNRMNEYQVLYKKKAYEPYLLEQFEWFERSPKADVSAFFDRVAANRRWVRTALRRAFE 4bqn B 1.38 BS01 COA B 1 S13 C14 C41 F42 V68 S69 Y72 Y97 H99 E163 L164 R167 N172 N200 R294 S11 C12 C39 F40 V66 S67 Y70 Y95 H97 E161 L162 R165 N170 N198 R292 Q63R74 AQRKKYSVYGSCQAPALAKMLNSCPTFARDWELVEMEPCFVASEEQIDRHLAETIPKLDLFLYQPVSEGYRGEKYSSVFLRNSMPPGGNALSVQYMHWEGYHPTVNSPYGLPPHPEGYVDALIAGAVVMDVDKETYLRHLEEIGASLRIDIDEIESWCVDELKTREVGENDGGKQIDISVTDFILANCRQKRLFYTMNHPTAALMREIAARCMLALGYTYSDISFDQNLDPLDVTKMSLYPIYRDCFDFSELNRMNEYQVLYKKKAYEPYLLEQFEWFERSPKADVSAFFDRVAANRRWVRTALRRAFE 4bqo A 1.56 BS01 COA A 1 S13 C14 C41 F42 S69 Y72 Y97 H99 E163 L164 R167 N172 R294 S10 C11 C38 F39 S66 Y69 Y94 H96 E160 L161 R164 N169 R291 Q63R74 QRKKYSVYGSCQAPALAKMLNSCPTFARDWELVEMEPCFVASEEQIDRHLAETIPKLDLFLYQPVSEGYRGEKYSSVFLRNSMPPGGNALSVQYMHWEGYHPTVNSPYGLPPHPEGYVDALIAGAVVMDVDKETYLRHLEEIGASLRIDIDEIESWCVDELKTREVGENDGGKQIDISVTDFILANCRQKRLFYTMNHPTAALMREIAARCMLALGYTYSDISFDQNLDPLDVTKMSLYPIYRDCFDFSELNRMNEYQVLYKKKAYEPYLLEQFEWFERSPKADVSAFFDRVAANRRWVRTALRRAFE 4bqo B 1.56 BS01 COA B 1 S13 C14 C41 F42 V68 S69 Y72 Y97 H99 E163 L164 R167 N172 N200 R294 S11 C12 C39 F40 V66 S67 Y70 Y95 H97 E161 L162 R165 N170 N198 R292 Q63R74 AQRKKYSVYGSCQAPALAKMLNSCPTFARDWELVEMEPCFVASEEQIDRHLAETIPKLDLFLYQPVSEGYRGEKYSSVFLRNSMPPGGNALSVQYMHWEGYHPTVNSPYGLPPHPEGYVDALIAGAVVMDVDKETYLRHLEEIGASLRIDIDEIESWCVDELKTREVGENDGGKQIDISVTDFILANCRQKRLFYTMNHPTAALMREIAARCMLALGYTYSDISFDQNLDPLDVTKMSLYPIYRDCFDFSELNRMNEYQVLYKKKAYEPYLLEQFEWFERSPKADVSAFFDRVAANRRWVRTALRRAFE 4bs9 A 2.90 BS01 ZN A 1 C209 C212 C318 C321 C196 C199 C293 C296 B2KYG8 PTALQIKPHFHVEIIEPKQVYLLGEQGNHALTGQLYCQILPFLNGEYTREQIVEKLDGQVPEEYIDFVLSRLVEKGYLTEVAPELSLEVAAFWSELGIAPSVVAEGLKQPVTVTTAGKGIREGIVANLAAALEEAGIQVSDPTAQLQVVLTDDYLQPELAAINKEALERQQPWLLVKPVGSILWLGPLFVPGETGCWHCLAQRLQGNREVEASVLQQKRALQERPTARATLPSTLQTGLQWAATEIAKWMVKRHLNAIAPGTARFPTLAGKIFTFNQTTLELKAHPLSRRPQCPTCGDRETLQRRGFEPLKLESRPKHPEQTVQKYQHLIGPITGVVTELVRSRASGLCEAIERYSGIFQGDEPRKRATLAELGDLAIHPEQCLHFSDRQYDNRESSNERATVTHDWIPQRFDASKAHDWTPVWSLTEQTHKYLPTALCYYRYPFPPEHRFCRSDSNGNAAGNTLEEAILQGFMELVERDSVCLWWYNRVSRPAVDLSSFDEPYFLQLQQFYQTQNRDLWVLDLTADLGIPAFVGVSNRKAGSSERIILGFGAHLDPTVAILRALTEVNQIGLELDATDWLVNATLAASPYLVADASQPLKTAKDYPRRWSDDIYTDVMTCVEIAKQAGLETLVLDQTRPDIGLNVVKVIVPGMRFWSRFGSGRLYDVPVKLGWREQPLAEAQMNPTPMPF 4bw0 B 2.33 BS01 NUC A 1 K30 G31 T32 N33 E34 K37 R41 D54 P55 I58 K79 I88 E89 V90 P91 C92 A93 K30 G31 T32 N33 E34 K37 R41 D54 P55 I58 K79 I88 E89 V90 P91 C92 A93 O29494 24149842 SYVRFEVPEDMQNEALSLLEKVRESGKVKKGTNETTKAVERGLAKLVYIAEDVDPPEIVAHLPLLCEEKNVPYIYVKSKNDLGRAVGIEVPCASAAIINEGELRKELGSLVEKIKGL 4c3x A 2.00 BS01 FAD A 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L445 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x B 2.00 BS01 FAD B 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x C 2.00 BS01 FAD C 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x D 2.00 BS01 FAD D 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 G476 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L445 G474 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x E 2.00 BS01 FAD E 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 G476 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L445 G474 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x F 2.00 BS01 FAD F 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x G 2.00 BS01 FAD G 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3x H 2.00 BS01 FAD H 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L445 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y A 2.30 BS01 FAD A 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 L445 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y A 2.30 BS02 ANB A 1 S52 F116 F294 Y318 Y487 P490 G491 S50 F114 F292 Y316 Y485 P488 G489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y B 2.30 BS01 FAD B 1 V13 G14 S15 G16 L36 E37 K38 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 W280 L447 G476 N477 G491 P493 L494 V11 G12 S13 G14 L34 E35 K36 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 W278 L442 G471 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y B 2.30 BS02 ANB B 1 S52 F116 F294 Y318 I354 Y487 P490 G491 S50 F114 F292 Y316 I352 Y482 P485 G486 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y C 2.30 BS01 FAD C 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 F294 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 F292 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y C 2.30 BS02 ANB C 1 S52 F116 Y318 I354 Y487 P490 G491 S50 F114 Y316 I352 Y482 P485 G486 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y D 2.30 BS01 FAD D 1 V13 G14 G16 L36 E37 K38 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 L447 G476 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 L445 G474 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y D 2.30 BS02 ANB D 1 S52 F116 Y119 F294 Y318 I354 Y487 P490 G491 S50 F114 Y117 F292 Y316 I352 Y485 P488 G489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y E 2.30 BS01 FAD E 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 L445 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y E 2.30 BS02 ANB E 1 S52 F116 Y119 Y318 I354 Y487 P490 G491 S50 F114 Y117 Y316 I352 Y485 P488 G489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y F 2.30 BS01 FAD F 1 V13 G14 G16 L36 E37 K38 G43 G44 T45 S46 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 G41 G42 T43 S44 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y F 2.30 BS02 ANB F 1 S52 F116 Y318 I354 Y487 P490 G491 S50 F114 Y316 I352 Y482 P485 G486 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y G 2.30 BS01 FAD G 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 Y48 S49 G50 A51 S52 S193 V194 L195 A229 G230 M252 A257 N258 D261 L447 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 Y46 S47 G48 A49 S50 S191 V192 L193 A227 G228 M250 A255 N256 D259 L442 N472 G486 P488 L489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y G 2.30 BS02 ANB G 1 S52 F116 F294 Y318 I354 Y487 P490 G491 S50 F114 F292 Y316 I352 Y482 P485 G486 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y H 2.30 BS01 FAD H 1 V13 G14 G16 L36 E37 K38 T39 G43 G44 T45 S46 S49 G50 A51 S52 L153 S193 V194 L195 A229 G230 M252 A257 N258 D261 L447 G476 N477 G491 P493 L494 V11 G12 G14 L34 E35 K36 T37 G41 G42 T43 S44 S47 G48 A49 S50 L151 S191 V192 L193 A227 G228 M250 A255 N256 D259 L445 G474 N475 G489 P491 L492 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c3y H 2.30 BS02 ANB H 1 S52 F116 F294 Y318 I354 Y487 P490 G491 S50 F114 F292 Y316 I352 Y485 P488 G489 1.3.99.4 Q9RA02 24165124 DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK 4c7a A 2.30 BS01 ZN A 1 T64 H65 T24 H25 Q90X26 FCKKSTTCEVLKYNTCLGSPLPYTHTSLILAEDSETQEEAFEKLAMWSGLRNAPRCWAVIQPLLCAVYMPKCENGKVELPSQHLCQATRNPCSIVERERGWPNFLKCENKEQFPKGC 4c8y A 1.80 BS01 NUC C 1 L19 G20 R22 G23 F24 Y26 R30 P34 H37 D38 Q39 G40 E41 N42 R83 G85 F128 R129 R141 L142 E145 S146 R149 G224 A225 K226 S228 L19 G20 R22 G23 F24 Y26 R30 P34 H37 D38 Q39 G40 E41 N42 R83 G85 F128 R129 R141 L142 E145 S146 R149 G224 A225 K226 S228 Q5SM65 24150936 MVLAALVLVLEGEGLPEPLGLRGFFYGLLREVAPEVHDQGENPFALGFGGREGAAWARVSLLVEGLYARLAPRLYALEGEEVRLGPPFRVRAVLQEGHPWAGVSTYPRLFQGPPSRDLALRFASPTFFRRKGVHYPVPEPRLVLESLLRRLEAFGPLKAPEGVREALLERTTVRSLEGRTLPARTEVDTAGFVGRVVYHLPRATEEEALWLSALGRFAFYSGVGAKTSLGYGRARAES 4c8z A 2.50 BS01 NUC C 1 R22 Y26 H37 D38 Q39 G40 E41 N42 F128 R129 R130 V133 H134 R141 L142 E145 S146 R149 E186 V187 D188 G224 A225 K226 S228 R22 Y26 H37 D38 Q39 G40 E41 N42 F128 R129 R130 V133 H134 R141 L142 E145 S146 R149 E186 V187 D188 G224 A225 K226 S228 Q5SM65 24150936 MVLAALVLVLEGEGLPEPLGLRGFFYGLLREVAPEVHDQGENPFALGFGGREGAAWARVSLLVEGLYARLAPRLYALEGEEVRLGPPFRVRAVLQEGHPWAGVSTYPRLFQGPPSRDLALRFASPTFFRRKGVHYPVPEPRLVLESLLRRLEAFGPLKAPEGVREALLERTTVRSLEGRTLPARTEVDTAGFVGRVVYHLPRATEEEALWLSALGRFAFYSGVGAKTSLGYGRARAES 4c8z B 2.50 BS01 NUC C 1 V173 R174 H199 P201 R202 V166 R167 H192 P194 R195 Q5SM65 24150936 MVLAALVLVLEGEGLPEPLGLRGFFYGLLREVAENPFALGFGGREGAAWARVSLLVEGLYARLAPRLYALEGEEVRLGPPFRVRAVLQEGHPWAGVSTYPRLFQGPPSRDLALRFASPTFFRRKGVHYPVPEPRLVLESLLRRLEAFGPLKAPEGVREALLERTTVRSLEGRTLPARTEVDTAGFVGRVVYHLPRATEEEALWLSALGRFAFYSGVGAKTSLGYGRARAES 4c98 A 2.00 BS01 ZN A 1 H23 H42 H27 H46 Q53VU8 24150936 GAASMPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPGTLRLRLTTLDDGLFAPFLRALSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL 4c9d A 3.00 BS01 NUC C 1 H23 H42 A44 P45 R46 K47 F144 A145 T146 S147 K148 P149 G151 T153 Y155 R162 L163 S167 D170 R208 K213 F215 G251 A252 K253 P255 Y256 H23 H42 A44 P45 R46 K47 F142 A143 T144 S145 K146 P147 G149 T151 Y153 R160 L161 S165 D168 R206 K211 F213 G249 A250 K251 P253 Y254 Q53VU8 24150936 MPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPGPEGATLKGTLRLRLTTLDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL 4c9d A 3.00 BS02 NUC D 1 E197 W228 E195 W226 Q53VU8 24150936 MPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPGPEGATLKGTLRLRLTTLDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL 4c9d B 3.00 BS01 NUC C 1 E197 W228 E193 W224 Q53VU8 24150936 ASMPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRTLKGTLRLRLTTLDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL 4c9d B 3.00 BS02 NUC D 1 H23 H42 A44 P45 K47 F144 A145 T146 S147 K148 P149 G150 T153 R154 Y155 R162 L163 S167 D170 R208 K213 G214 F216 P217 G251 A252 K253 P255 Y256 H25 H44 A46 P47 K49 F140 A141 T142 S143 K144 P145 G146 T149 R150 Y151 R158 L159 S163 D166 R204 K209 G210 F212 P213 G247 A248 K249 P251 Y252 Q53VU8 24150936 ASMPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRTLKGTLRLRLTTLDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL 4g32 A 1.75 BS01 FE2 A 1 H377 H382 H555 N559 I685 H322 H327 H500 N504 I630 1.13.11.- Q8RNT4 23985801 IPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFANVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIAAGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIALLTRVGLLVDDILKSASNLVDGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 4g32 A 1.75 BS02 ZPE A 1 I117 L182 V185 G186 D190 L193 E373 H377 H382 F415 I416 G419 A420 R422 I423 L424 F430 N607 Y609 L612 I685 I68 L133 V136 G137 D141 L144 E318 H322 H327 F360 I361 G364 A365 R367 I368 L369 F375 N552 Y554 L557 I630 1.13.11.- Q8RNT4 23985801 IPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFANVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIAAGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIALLTRVGLLVDDILKSASNLVDGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 4g33 A 2.03 BS01 FE2 A 1 H377 H382 H555 N559 I685 H353 H358 H531 N535 I661 1.13.11.- Q8RNT4 23985801 ANDSIFFSPLKYLGAEQQRSIDASRSLLDNLIPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFANVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIAAGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIALLTRVGLLVDDILKSASNLVDGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 4g33 A 2.03 BS02 ZPE A 1 W105 T109 I113 I117 L182 V185 D190 E373 H377 H382 F415 I416 G419 A420 I423 L424 I431 N607 Y609 L611 L612 I685 W87 T91 I95 I99 L164 V167 D172 E349 H353 H358 F391 I392 G395 A396 I399 L400 I407 N583 Y585 L587 L588 I661 1.13.11.- Q8RNT4 23985801 ANDSIFFSPLKYLGAEQQRSIDASRSLLDNLIPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFANVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIAAGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIALLTRVGLLVDDILKSASNLVDGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAGLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 4hf8 A 2.45 BS01 PLG A 1 S87 G88 I89 Y113 E156 N160 D185 T187 F188 S207 T209 K210 S339 L340 R374 S86 G87 I88 Y112 E155 N159 D184 T186 F187 S206 T208 K209 S338 L339 R373 4.4.1.11 Q84AR1 SDCRTYGFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTDALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLSHSMPKFGINVRFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGALLVVDNTFMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMSLPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKAT 4hf8 A 2.45 BS02 GLY A 1 H355 V358 H354 V357 4.4.1.11 Q84AR1 SDCRTYGFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTDALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLSHSMPKFGINVRFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGALLVVDNTFMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMSLPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKAT 4hzv A 1.80 BS01 FUC A 1 N306 N307 N226 N227 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzv A 1.80 BS02 CA A 1 D293 N294 G297 D324 G345 P347 G348 D213 N214 G217 D243 G263 P265 G266 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzw A 1.70 BS01 CA A 1 D293 N294 G297 D324 G345 P347 G348 D213 N214 G217 D243 G263 P265 G266 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzw A 1.70 BS02 LNV A 1 R118 E119 D151 R152 R156 W178 I222 R224 E227 A246 E276 E277 R292 R371 Y406 R37 E38 D70 R71 R75 W98 I142 R144 E147 A166 E197 E198 R212 R289 Y324 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzx A 2.20 BS01 FUC A 1 N306 N307 N226 N227 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzx A 2.20 BS02 CA A 1 D293 G297 D324 G345 P347 G348 D213 G217 D243 G263 P265 G266 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzx A 2.20 BS03 G39 A 1 R118 E119 D151 R152 W178 I222 R224 A246 E276 R292 N294 R371 Y406 R37 E38 D70 R71 W98 I142 R144 A166 E197 R212 N214 R289 Y324 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQHLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzy A 1.60 BS01 CA A 1 D293 G297 S298 D324 G345 G348 D213 G217 S218 D243 G263 G266 A9YN63 23824808 FRPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQYLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzz A 1.60 BS01 CA A 1 D293 G297 D324 G345 G348 D212 G216 D242 G262 G265 A9YN63 23824808 RPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQYLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4hzz A 1.60 BS02 G39 A 1 R118 E119 D151 R152 R224 E276 R292 R371 Y406 R36 E37 D69 R70 R143 E196 R211 R288 Y323 A9YN63 23824808 RPFKSPLPLCPFRGFFPFHKDNAIRLGENKDVIVTREPYVSCDNDNCWSFALAQGALLGTKHSNGTIKDRTPYRSLIRFPIGTAPVLGNYKEICIAWSSSSCFDGKEWMHVCMTGNDNDASAQIIYGGRMTDSIKSWRKDILRTQESECQCIDGTCVVAVTDGPAANSADYRVYWIREGKIIKYENVPKTKIQYLEECSCYVDIDVYCICRDNWKGSNRPWMRINNETILETGYVCSKFHSDTPRPADPSTMSCDSPSNVNGGPGVKGFGFKAGDDVWLGRTVSTSGRSGFEIIKVTEGWINSPNHVKSITQTLVSNNDWSGYSGSFIVKAKDCFQPCFYVELIRGRPNKNDDVSWTSNSIVTFCGLDNEPGSGNWPDGSNIGFMPK 4ig9 A 2.64 BS01 III B 1 K236 N241 T242 I243 R466 P468 F474 D475 E477 L478 L479 G480 D481 I485 E488 R492 K4 N9 T10 I11 R234 P236 F242 D243 E245 L246 L247 G248 D249 I253 E256 R260 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLC 4ig9 A 2.64 BS02 ZN A 1 C371 C374 C395 C398 C139 C142 C163 C166 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLC 4ig9 C 2.64 BS01 III D 1 K236 N241 T242 I243 F474 D475 E477 L478 L479 I485 E488 K4 N9 T10 I11 F242 D243 E245 L246 L247 I253 E256 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLC 4ig9 C 2.64 BS02 ZN C 1 C371 C374 C395 C398 C139 C142 C163 C166 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLC 4ig9 E 2.64 BS01 III F 1 K236 N241 T242 I243 F474 D475 E477 L478 L479 I485 E488 H491 K5 N10 T11 I12 F243 D244 E246 L247 L248 I254 E257 H260 3.5.1.- Q96EB6 24120939 HMRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLC 4ig9 E 2.64 BS02 ZN E 1 C371 C374 C395 C398 C140 C143 C164 C167 3.5.1.- Q96EB6 24120939 HMRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLC 4ig9 G 2.64 BS01 III H 1 K236 N241 T242 I243 R466 P468 F474 D475 E477 L478 L479 G480 D481 I485 E488 R492 K4 N9 T10 I11 R234 P236 F242 D243 E245 L246 L247 G248 D249 I253 E256 R260 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCC 4ig9 G 2.64 BS02 ZN G 1 C371 C374 C395 C398 C139 C142 C163 C166 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCC 4ige A 2.15 BS01 CHJ A 1 A217 N218 A219 V222 Y267 Y277 A319 A320 I323 F368 I369 A120 N121 A122 V125 Y170 Y180 A222 A223 I226 F228 I229 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAITFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4ige A 2.15 BS02 NAD A 1 G104 I105 G106 G110 Y111 W131 F167 D168 A169 S215 L216 A217 N218 L265 T266 Y267 K285 A312 G313 P314 L315 S317 A319 G8 I9 G10 G14 Y15 W35 F71 D72 A73 S118 L119 A120 N121 L168 T169 Y170 K188 A215 G216 P217 L218 S220 A222 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAITFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4ige B 2.15 BS01 CHJ B 1 A217 N218 A219 Y267 Y277 A319 A320 F368 I369 A121 N122 A123 Y171 Y181 A223 A224 F231 I232 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4ige B 2.15 BS02 NAD B 1 I105 G106 G110 Y111 W131 F167 D168 A169 S170 S215 L216 A217 N218 L265 T266 Y267 K285 A312 G313 P314 L315 S317 A319 I369 I9 G10 G14 Y15 W35 F71 D72 A73 S74 S119 L120 A121 N122 L169 T170 Y171 K189 A216 G217 P218 L219 S221 A223 I232 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4igf A 2.30 BS01 CHV A 1 A217 A219 V222 Y267 Y277 F368 I369 A120 A122 V125 Y170 Y180 F221 I222 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4igf A 2.30 BS02 NAD A 1 G104 I105 G106 G110 Y111 W131 F167 D168 A169 S215 L216 A217 L265 T266 Y267 K285 A312 G313 P314 L315 S317 I369 G8 I9 G10 G14 Y15 W35 F71 D72 A73 S118 L119 A120 L168 T169 Y170 K188 A215 G216 P217 L218 S220 I222 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4igf B 2.30 BS01 CHV B 1 A217 N218 A219 V222 Y267 Y277 A319 A320 I323 F368 A121 N122 A123 V126 Y171 Y181 A223 A224 I227 F231 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4igf B 2.30 BS02 NAD B 1 G104 I105 G106 G110 Y111 W131 F167 D168 A169 S215 L216 A217 N218 L265 T266 Y267 K285 A312 G313 P314 L315 S317 A319 I369 G8 I9 G10 G14 Y15 W35 F71 D72 A73 S119 L120 A121 N122 L169 T170 Y171 K189 A216 G217 P218 L219 S221 A223 I232 1.3.1.9 C6KSZ2 24063369 EDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPD 4iit A 4.30 BS01 FAQ A 1 R33 Q37 K103 Y104 S105 S106 M193 M194 G196 P197 S202 P203 N204 K214 N218 F264 I268 R33 Q37 K103 Y104 S105 S106 M193 M194 G196 P197 S202 P203 N204 K214 N218 F264 I268 1.14.13.- A6T8I0 24055609 STEEQRFDQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIVGMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDLYQKMLDGQMKYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQRQGFEACMALAQGNEAQRQMLQDAINRFWWPALMMFGPNDDNSPNSARSMAWKIKLHSNDELRQRFVDNTVPQVEILGMTVPDPDLQFDEASGHYRFGEIDWQEFNEVISGRGICNHERLAAKRKAWEEGEWVREAALAHAQK 4ij3 B 2.70 BS01 PO4 B 1 E185 R188 H189 E185 R188 H189 23867277 DVVMTQSHKFMSTSVGDRVSITCKASQDVSTAVAWYQQKSGQSPKLLIHSASYRYTGVPDRFTGSGSGTDFTFTISSVQAEDLAVYYCQQHYSIPLTFGAGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC 4imf A 1.90 BS01 SI3 A 1 A10 G46 S47 T48 Y136 I138 T166 G188 F189 D190 E191 I205 G206 S207 L250 Y251 A9 G45 S46 T47 Y135 I137 T165 G187 F188 D189 E190 I204 G205 S206 L249 Y250 4.1.3.3 Q9CKB0 24152047 KNLKGIFSALLVSFNADGSINEKGLRQIVRYNIDKMKVDGLYVGGSTGENFMLSTEEKKEIFRIAKDEAKDEIALIAQVGSVNLQEAIELGKYATELGYDSLSAVTPFYYKFSFPEIKHYYDSIIEATGNYMIVYSIPFLTGVNIGVEQFGELYKNPKVLGVAFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTQAGKLKEALEIQHVTNDLIEGILANGLYLTIKELLKLDGVEAGYCREPMTKELSSEKVAFAKELKAKYLS 4imf B 1.90 BS01 SI3 B 1 A10 G46 S47 T48 Y136 I138 T166 G188 F189 D190 E191 I205 G206 S207 L250 Y251 A9 G45 S46 T47 Y135 I137 T165 G187 F188 D189 E190 I204 G205 S206 L249 Y250 4.1.3.3 Q9CKB0 24152047 KNLKGIFSALLVSFNADGSINEKGLRQIVRYNIDKMKVDGLYVGGSTGENFMLSTEEKKEIFRIAKDEAKDEIALIAQVGSVNLQEAIELGKYATELGYDSLSAVTPFYYKFSFPEIKHYYDSIIEATGNYMIVYSIPFLTGVNIGVEQFGELYKNPKVLGVAFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTQAGKLKEALEIQHVTNDLIEGILANGLYLTIKELLKLDGVEAGYCREPMTKELSSEKVAFAKELKAKYLS 4img A 1.85 BS01 NGF A 1 A10 G46 S47 T48 Y136 I138 F140 T166 G188 F189 D190 E191 G206 S207 L250 Y251 A10 G46 S47 T48 Y136 I138 F140 T166 G188 F189 D190 E191 G206 S207 L250 Y251 4.1.3.3 Q9CKB0 24152047 MKNLKGIFSALLVSFNADGSINEKGLRQIVRYNIDKMKVDGLYVGGSTGENFMLSTEEKKEIFRIAKDEAKDEIALIAQVGSVNLQEAIELGKYATELGYDSLSAVTPFYYKFSFPEIKHYYDSIIEATGNYMIVYSIPFLTGVNIGVEQFGELYKNPKVLGVAFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTQAGKLKEALEIQHVTNDLIEGILANGLYLTIKELLKLDGVEAGYCREPMTKELSSEKVAFAKELKAKYLS 4img B 1.85 BS01 NGF B 1 A10 Y43 G46 S47 T48 Y136 I138 T166 G188 F189 D190 E191 G206 S207 L250 Y251 A10 Y43 G46 S47 T48 Y136 I138 T166 G188 F189 D190 E191 G206 S207 L250 Y251 4.1.3.3 Q9CKB0 24152047 MKNLKGIFSALLVSFNADGSINEKGLRQIVRYNIDKMKVDGLYVGGSTGENFMLSTEEKKEIFRIAKDEAKDEIALIAQVGSVNLQEAIELGKYATELGYDSLSAVTPFYYKFSFPEIKHYYDSIIEATGNYMIVYSIPFLTGVNIGVEQFGELYKNPKVLGVAFTAGDFYLLERLKKAYPNHLIWAGFDEMMLPAASLGVDGAIGSTFNVNGVRARQIFELTQAGKLKEALEIQHVTNDLIEGILANGLYLTIKELLKLDGVEAGYCREPMTKELSSEKVAFAKELKAKYLS 4ipz A 1.67 BS01 III B 1 R55 F60 Q63 G72 A101 N102 A103 Q111 F113 W121 L122 H126 R54 F59 Q62 G71 A99 N100 A101 Q109 F111 W119 L120 H124 5.2.1.8 P62937 VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE 4j2x A 2.85 BS01 III B 1 G234 N235 F236 E257 E259 E260 F261 T262 V263 D265 K275 V277 G282 M283 A284 P286 R330 I331 I332 Q333 G182 N183 F184 E205 E207 E208 F209 T210 V211 D213 K223 V225 G230 M231 A232 P234 R278 I279 I280 Q281 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTP 4j2x A 2.85 BS02 NUC G 1 K84 Y86 R91 D158 S191 K192 S194 K196 R220 Q222 K32 Y34 R39 D106 S139 K140 S142 K144 R168 Q170 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTP 4j2x A 2.85 BS03 NUC H 1 K90 R91 F92 K192 R218 S221 T223 K295 K311 K38 R39 F40 K140 R166 S169 T171 K243 K259 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTP 4j2x C 2.85 BS01 III D 1 G234 N235 F236 E257 E259 E260 F261 T262 V263 D265 K275 V277 G282 M283 A284 L285 P286 L324 I331 I332 Q333 G182 N183 F184 E205 E207 E208 F209 T210 V211 D213 K223 V225 G230 M231 A232 L233 P234 L272 I279 I280 Q281 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPE 4j2x C 2.85 BS02 NUC E 1 K84 Y86 D158 S191 K192 S194 K196 R220 Q222 V224 K32 Y34 D106 S139 K140 S142 K144 R168 Q170 V172 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPE 4j2x C 2.85 BS03 NUC F 1 K90 R91 F92 K192 K195 R218 S221 T223 K311 K38 R39 F40 K140 K143 R166 S169 T171 K259 P31266 PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPE 4j4j A 3.10 BS01 ZN A 1 H249 C280 C283 H59 C90 C93 3.5.4.5 Q8IUX4 QGSAMDPPTFTFNFNNEPWVRGRHETYLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 4j4j B 3.10 BS01 ZN B 1 H249 C280 C283 H59 C90 C93 3.5.4.5 Q8IUX4 QGSAMDPPTFTFNFNNEPWVRGRHETYLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE 4ji0 B 3.49 BS01 NUC A 1 K22 R23 W24 P26 E35 N37 G38 R96 G99 G100 T103 N104 I108 R111 R144 K147 Y148 I172 E176 K179 K16 R17 W18 P20 E29 N31 G32 R90 G93 G94 T97 N98 I102 R105 R138 K141 Y142 I166 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji0 B 3.49 BS02 MG B 1 R96 L98 R90 L92 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji0 B 3.49 BS03 MG B 2 H19 E20 K74 D166 D189 D191 D205 D206 H13 E14 K68 D160 D183 D185 D199 D200 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji0 C 3.49 BS01 NUC A 1 G2 N3 K4 I5 F10 R126 K150 S154 G155 R156 E161 Q162 A163 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 L188 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 R125 K149 S153 G154 R155 E160 Q161 A162 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 L187 R189 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji0 C 3.49 BS02 MG C 1 F128 A129 V130 R131 I157 F127 A128 V129 R130 I156 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji0 D 3.49 BS01 NUC A 1 G2 I5 P7 V8 C9 R10 R13 R14 L21 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 R59 Q62 R65 R66 S71 E72 R73 Q74 N77 K84 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 L155 E156 E205 S208 R209 G1 I4 P6 V7 C8 R9 R12 R13 L20 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 R58 Q61 R64 R65 S70 E71 R72 Q73 N76 K83 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 L154 E155 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji0 D 3.49 BS02 ZN D 1 C9 C12 C26 C31 C8 C11 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji0 D 3.49 BS03 MG D 1 W173 R187 W172 R186 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji0 D 3.49 BS04 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji0 E 3.49 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 G23 R24 R25 R27 K47 P49 K57 Y60 Y61 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 G19 R20 R21 R23 K43 P45 K53 Y56 Y57 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji0 F 3.49 BS01 NUC A 1 R2 Y4 Y50 K54 E69 N73 R77 R87 M89 V90 K92 R2 Y4 Y50 K54 E69 N73 R77 R87 M89 V90 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji0 F 3.49 BS02 MG F 1 R80 R82 V85 R80 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji0 G 3.49 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 G82 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 G81 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji0 H 3.49 BS01 NUC A 1 M1 L2 T3 D4 P5 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 G130 E132 M1 L2 T3 D4 P5 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 G130 E132 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji0 I 3.49 BS01 NUC A 1 E2 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 E1 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji0 J 3.49 BS01 NUC A 1 R5 K7 H13 S35 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 E97 R3 K5 H11 S33 P35 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 E95 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji0 J 3.49 BS02 MG J 1 K57 R60 K55 R58 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji0 K 3.49 BS01 NUC A 1 Y20 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 V47 K51 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 N16 N17 I19 T21 G27 N28 P29 W32 S34 G36 V37 K41 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji0 L 3.49 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K17 R19 K21 S22 K23 V24 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 T61 Y69 G72 E73 R86 G87 K91 D92 L94 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K13 R15 K17 S18 K19 V20 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 G68 E69 R82 G83 K87 D88 L90 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLLGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji0 M 3.49 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 K27 A28 R29 R44 V74 N77 I78 R80 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 K26 A27 R28 R43 V73 N76 I77 R79 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji0 N 3.49 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K11 K15 F16 K17 V18 R19 Y21 T22 R23 R26 C27 R29 A30 R31 S32 V33 Y34 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K10 K14 F15 K16 V17 R18 Y20 T21 R22 R25 C26 R28 A29 R30 S31 V32 Y33 R34 R40 I41 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji0 N 3.49 BS02 ZN N 1 C24 C27 R29 C40 C43 C23 C26 R28 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji0 O 3.49 BS01 NUC A 1 P2 K8 F18 D21 T22 G23 S24 Q28 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 G61 R64 R65 L66 R68 Y69 R72 E73 P1 K7 F17 D20 T21 G22 S23 Q27 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 G60 R63 R64 L65 R67 Y68 R71 E72 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji0 P 3.49 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 K35 Y38 P41 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 K35 Y38 P41 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji0 Q 3.49 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 N94 Y95 S97 L98 S99 K100 P1 K2 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 N93 Y94 S96 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji0 Q 3.49 BS02 MG Q 1 D13 M15 E49 D12 M14 E48 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji0 R 3.49 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 K31 I32 R35 A42 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji0 S 3.49 BS01 NUC A 1 P2 R3 S4 K6 F10 H14 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 Y80 R81 P1 R2 S3 K5 F9 H13 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 Y79 R80 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji0 T 3.49 BS01 NUC A 1 R8 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 R25 N26 K27 A28 K29 S31 K34 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 R80 K81 S82 R83 M85 R86 K87 R89 G101 G102 G103 L104 S105 R1 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 R18 N19 K20 A21 K22 S24 K27 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 R73 K74 S75 R76 M78 R79 K80 R82 G94 G95 G96 L97 S98 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji1 B 3.14 BS01 NUC A 1 K22 W24 P26 L98 G99 G100 T103 N104 T107 I108 R111 K133 R144 Y148 I172 E176 K179 K16 W18 P20 L92 G93 G94 T97 N98 T101 I102 R105 K127 R138 Y142 I166 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji1 B 3.14 BS02 MG B 1 E20 K74 D166 D191 D205 E14 K68 D160 D185 D199 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji1 B 3.14 BS03 MG B 2 P194 V197 I200 P188 V191 I194 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji1 C 3.14 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 K27 R126 S154 R156 G158 G159 E161 Q162 A163 W167 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 K26 R125 S153 R155 G157 G158 E160 Q161 A162 W166 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji1 D 3.14 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K84 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 R141 K151 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K83 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 R140 K150 E155 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji1 D 3.14 BS02 ZN D 1 C9 C12 C26 C31 C8 C11 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji1 D 3.14 BS03 MG D 1 W173 R187 W172 R186 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji1 D 3.14 BS04 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji1 E 3.14 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y60 Y61 A86 K92 A94 A95 T98 I101 A102 G103 R107 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y56 Y57 A82 K88 A90 A91 T94 I97 A98 G99 R103 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji1 F 3.14 BS01 NUC A 1 R2 Y4 Y50 K54 E69 N73 R80 R87 V90 V91 K92 R2 Y4 Y50 K54 E69 N73 R80 R87 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji1 F 3.14 BS02 MG F 1 R80 R82 R80 R82 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji1 G 3.14 BS01 NUC A 1 A2 R3 R4 R5 R6 A7 R10 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 R4 R5 A6 R9 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji1 H 3.14 BS01 NUC A 1 M1 L2 T3 D4 P5 D8 T11 R12 R14 N15 V19 K21 S29 R30 K56 R75 K88 P89 R91 R92 Y94 V95 G96 V97 K98 S113 T114 S115 G128 G130 E132 M1 L2 T3 D4 P5 D8 T11 R12 R14 N15 V19 K21 S29 R30 K56 R75 K88 P89 R91 R92 Y94 V95 G96 V97 K98 S113 T114 S115 G128 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji1 H 3.14 BS02 MG H 1 K21 E22 K21 E22 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji1 H 3.14 BS03 MG H 2 R14 H82 I83 R14 H82 I83 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji1 I 3.14 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 G30 Y36 Q38 G39 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 K116 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 G29 Y35 Q37 G38 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 K115 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji1 J 3.14 BS01 NUC A 1 R5 K7 R9 H13 V34 S35 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 I50 R51 G52 P53 F54 K55 H56 K57 R60 H62 H68 R70 L71 D73 E97 R3 K5 R7 H11 V32 S33 P35 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 I48 R49 G50 P51 F52 K53 H54 K55 R58 H60 H66 R68 L69 D71 E95 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji1 J 3.14 BS02 MG J 1 K57 R60 K55 R58 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji1 J 3.14 BS03 MG J 2 R51 R60 E61 H62 R49 R58 E59 H60 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji1 K 3.14 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 D36 G37 N38 P39 I40 W42 S44 G46 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 H12 N16 N17 I19 T21 D26 G27 N28 P29 I30 W32 S34 G36 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 4ji1 K 3.14 BS02 MG K 1 Y25 N26 Y15 N16 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 4ji1 L 3.14 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K17 V18 R19 K20 K21 S22 K23 K28 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 T61 Y69 P71 G72 E73 L84 R86 V90 K91 D92 L94 R97 V101 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K13 V14 R15 K16 K17 S18 K19 K24 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 P67 G68 E69 L80 R82 V86 K87 D88 L90 R93 V97 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLLGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji1 M 3.14 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 V74 N77 I78 Y87 R88 R91 H92 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 V73 N76 I77 Y86 R87 R90 H91 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVA 4ji1 N 3.14 BS01 NUC A 1 A2 R3 K4 A5 L6 K15 F16 K17 V18 R19 Y21 T22 R23 C27 R29 R31 S32 V33 Y34 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 K14 F15 K16 V17 R18 Y20 T21 R22 C26 R28 R30 S31 V32 Y33 R34 R40 I41 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji1 N 3.14 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji1 N 3.14 BS03 MG N 1 T22 A30 V33 T21 A29 V32 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji1 O 3.14 BS01 NUC A 1 P2 K8 F18 D21 T22 G23 S24 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 G61 R64 R65 L66 R68 Y69 R72 P1 K7 F17 D20 T21 G22 S23 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 G60 R63 R64 L65 R67 Y68 R71 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4ji1 P 3.14 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 Y38 P41 R42 K43 T44 T45 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 Y38 P41 R42 K43 T44 T45 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji1 Q 3.14 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 R91 N94 Y95 S97 L98 S99 K100 R101 G102 G103 K104 A105 P1 K2 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 R90 N93 Y94 S96 L97 S98 K99 R100 G101 G102 K103 A104 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKRGGKA 4ji1 Q 3.14 BS02 MG Q 1 D13 M15 D12 M14 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKRGGKA 4ji1 R 3.14 BS01 NUC A 1 K49 I50 P52 R53 A60 K61 Q63 R64 K68 K71 R72 R74 I75 F81 K34 I35 P37 R38 A45 K46 Q48 R49 K53 K56 R57 R59 I60 F66 Q5SLQ0 24152548 PSRKAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji1 S 3.14 BS01 NUC A 1 P2 R3 S4 K6 K7 F10 H14 K18 W34 R36 R37 Y52 N53 G54 K55 K70 E73 T77 R78 T79 Y80 R81 P1 R2 S3 K5 K6 F9 H13 K17 W33 R35 R36 Y51 N52 G53 K54 K69 E72 T76 R77 T78 Y79 R80 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji1 T 3.14 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 K29 S31 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R86 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 K22 S24 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R79 R82 G94 G95 G96 L97 S98 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji1 T 3.14 BS02 MG T 1 S11 A12 S4 A5 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji2 B 3.64 BS01 NUC A 1 R21 K22 R23 W24 P26 E35 N37 G38 R96 L98 G99 G100 T103 N104 R111 R144 Y148 I172 E176 K179 R15 K16 R17 W18 P20 E29 N31 G32 R90 L92 G93 G94 T97 N98 R105 R138 Y142 I166 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji2 B 3.64 BS02 MG B 1 R96 L98 R90 L92 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji2 B 3.64 BS03 MG B 2 E20 K74 D166 D191 D205 E14 K68 D160 D185 D199 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji2 B 3.64 BS04 MG B 3 R53 T54 Y199 I200 R47 T48 Y193 I194 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji2 C 3.64 BS01 NUC A 1 G2 N3 K4 I5 I14 K27 R126 S154 G155 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 L188 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 I13 K26 R125 S153 G154 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 L187 R189 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji2 C 3.64 BS02 MG C 1 F128 A129 V130 R131 I157 F127 A128 V129 R130 I156 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji2 D 3.64 BS01 NUC A 1 G2 I5 P7 V8 C9 R10 R13 R14 L21 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 S52 Y54 A55 R59 K61 Q62 R65 R66 S71 E72 R73 Q74 K84 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 L155 E205 S208 R209 G1 I4 P6 V7 C8 R9 R12 R13 L20 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 S51 Y53 A54 R58 K60 Q61 R64 R65 S70 E71 R72 Q73 K83 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 L154 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji2 D 3.64 BS02 ZN D 1 C9 C12 C26 C31 C8 C11 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji2 D 3.64 BS03 MG D 1 W173 R187 W172 R186 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji2 D 3.64 BS04 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji2 E 3.64 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y60 Y61 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y56 Y57 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji2 F 3.64 BS01 NUC A 1 R2 Y4 Y50 K54 N73 R77 R87 M89 V90 V91 K92 R2 Y4 Y50 K54 N73 R77 R87 M89 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji2 F 3.64 BS02 MG F 1 R80 R82 V85 R80 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji2 G 3.64 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 G82 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 G81 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji2 H 3.64 BS01 NUC A 1 M1 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 G130 E132 M1 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji2 I 3.64 BS01 NUC A 1 E2 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 E1 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji2 I 3.64 BS02 MG I 1 V108 V109 V107 V108 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji2 J 3.64 BS01 NUC A 1 R5 K7 H13 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 P53 F54 K55 H56 K57 S59 R60 E61 H62 H68 R70 E97 R3 K5 H11 D15 S33 G34 P35 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 P51 F52 K53 H54 K55 S57 R58 E59 H60 H66 R68 E95 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji2 J 3.64 BS02 MG J 1 K57 R60 K55 R58 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji2 K 3.64 BS01 NUC A 1 Y20 N26 N27 I29 T31 T33 G37 N38 P39 W42 S44 G46 V47 G52 S53 K55 K71 R85 P113 V114 P115 H116 N117 G118 C119 R120 K122 K123 K124 Y10 N16 N17 I19 T21 T23 G27 N28 P29 W32 S34 G36 V37 G42 S43 K45 K61 R75 P103 V104 P105 H106 N107 G108 C109 R110 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji2 L 3.64 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K17 R19 K21 S22 K23 V24 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 K57 T61 Y69 G72 E73 R86 G87 V90 K91 D92 W94 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K13 R15 K17 S18 K19 V20 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 K53 T57 Y65 G68 E69 R82 G83 V86 K87 D88 W90 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLWGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji2 M 3.64 BS01 NUC A 1 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 V74 N77 I78 L81 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 V73 N76 I77 L80 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji2 N 3.64 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K11 K15 F16 K17 V18 R19 Y21 T22 R23 R26 C27 R29 A30 R31 S32 Y34 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K10 K14 F15 K16 V17 R18 Y20 T21 R22 R25 C26 R28 A29 R30 S31 Y33 R34 R40 I41 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji2 N 3.64 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji2 O 3.64 BS01 NUC A 1 P2 K8 Q9 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 G61 R64 R65 L66 Y69 R72 P1 K7 Q8 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 G60 R63 R64 L65 Y68 R71 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji2 P 3.64 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 K43 T44 K50 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 K43 T44 K50 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji2 P 3.64 BS02 MG P 1 K35 I36 K35 I36 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji2 Q 3.64 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 T20 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 I90 R91 N94 Y95 L98 S99 K100 P1 K2 S11 K13 M14 Q15 K16 T17 T19 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 I89 R90 N93 Y94 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji2 Q 3.64 BS02 MG Q 1 D13 M15 E49 D12 M14 E48 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji2 R 3.64 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 K68 K71 R72 R74 I75 F81 K31 I32 R35 A42 K43 Q45 R46 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji2 S 3.64 BS01 NUC A 1 P2 R3 S4 K6 K7 F10 H14 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 T79 Y80 P1 R2 S3 K5 K6 F9 H13 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 T78 Y79 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji2 T 3.64 BS01 NUC A 1 L10 K14 R15 H16 R17 S19 K21 R22 R23 N26 K27 S31 T35 K38 K39 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 R80 K81 S82 R83 M85 R86 R89 G101 G102 G103 L104 S105 L3 K7 R8 H9 R10 S12 K14 R15 R16 N19 K20 S24 T28 K31 K32 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 R73 K74 S75 R76 M78 R79 R82 G94 G95 G96 L97 S98 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji3 B 3.35 BS01 NUC A 1 K22 W24 P26 R96 G99 G100 T103 N104 T107 R111 K132 K133 R144 Y148 I172 E176 K179 K16 W18 P20 R90 G93 G94 T97 N98 T101 R105 K126 K127 R138 Y142 I166 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji3 B 3.35 BS02 MG B 1 D166 D191 D205 D206 D160 D185 D199 D200 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji3 B 3.35 BS03 MG B 2 E50 R53 T54 D198 Y199 I200 E44 R47 T48 D192 Y193 I194 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji3 C 3.35 BS01 NUC A 1 G2 N3 K4 I5 F10 K27 R126 R127 S154 G155 R156 G158 G159 E161 A163 W167 R172 V173 P174 L175 H176 T177 L178 R179 F186 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K26 R125 R126 S153 G154 R155 G157 G158 E160 A162 W166 R171 V172 P173 L174 H175 T176 L177 R178 F185 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji3 C 3.35 BS02 MG C 1 R179 A180 N181 I182 R178 A179 N180 I181 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji3 D 3.35 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 L21 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K86 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 L20 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K85 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 L154 E155 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji3 D 3.35 BS02 ZN D 1 C9 C12 C26 C31 C8 C11 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji3 D 3.35 BS03 MG D 1 W173 R187 W172 R186 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji3 D 3.35 BS04 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji3 E 3.35 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 P49 K57 Y60 Y61 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 P45 K53 Y56 Y57 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji3 F 3.35 BS01 NUC A 1 R2 Y4 Y50 K54 E69 N73 R77 R80 R87 M89 V90 V91 K92 R2 Y4 Y50 K54 E69 N73 R77 R80 R87 M89 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji3 F 3.35 BS02 MG F 1 R80 R82 V85 R80 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji3 G 3.35 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 R94 R95 S98 R102 N109 R114 A116 R119 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 R93 R94 S97 R101 N108 R113 A115 R118 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji3 H 3.35 BS01 NUC A 1 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 G130 E132 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji3 H 3.35 BS02 MG H 1 K21 E22 K21 E22 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji3 I 3.35 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji3 J 3.35 BS01 NUC A 1 R5 K7 H13 S35 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 I50 R51 G52 F54 K55 H56 K57 S59 R60 H62 H68 D73 R3 K5 H11 S33 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 I48 R49 G50 F52 K53 H54 K55 S57 R58 H60 H66 D71 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji3 K 3.35 BS01 NUC A 1 Y20 N26 N27 I29 T31 D36 G37 N38 P39 I40 W42 S44 G46 G52 S53 K55 K71 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 N16 N17 I19 T21 D26 G27 N28 P29 I30 W32 S34 G36 G42 S43 K45 K61 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji3 L 3.35 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K17 V18 K20 S22 K23 G29 A30 P31 F32 R33 R34 K46 N49 S50 A51 L52 R53 K54 T61 Y69 P71 G72 E73 R86 G87 V90 K91 D92 W94 R97 V101 V104 Y105 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K13 V14 K16 S18 K19 G25 A26 P27 F28 R29 R30 K42 N45 S46 A47 L48 R49 K50 T57 Y65 P67 G68 E69 R82 G83 V86 K87 D88 W90 R93 V97 V100 Y101 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLWGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji3 M 3.35 BS01 NUC A 1 R14 V17 Y21 Y23 G24 I25 G26 A28 R29 V74 N77 I78 R80 Y87 R88 R91 H92 L96 P97 V98 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 R13 V16 Y20 Y22 G23 I24 G25 A27 R28 V73 N76 I77 R79 Y86 R87 R90 H91 L95 P96 V97 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji3 N 3.35 BS01 NUC A 1 A2 R3 K4 A5 L6 F16 K17 V18 R19 Y21 T22 R23 C27 R29 R31 S32 V33 Y34 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 F15 K16 V17 R18 Y20 T21 R22 C26 R28 R30 S31 V32 Y33 R34 R40 I41 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji3 N 3.35 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji3 N 3.35 BS03 MG N 1 T22 A30 T21 A29 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji3 O 3.35 BS01 NUC A 1 P2 K8 F18 D21 T22 G23 S24 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 G61 R64 R65 L66 R68 Y69 R72 P1 K7 F17 D20 T21 G22 S23 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 G60 R63 R64 L65 R67 Y68 R71 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji3 P 3.35 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 K35 Y38 P41 R42 K43 T44 T45 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 K35 Y38 P41 R42 K43 T44 T45 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji3 Q 3.35 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 R91 N94 Y95 S97 L98 S99 K100 P1 K2 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 R90 N93 Y94 S96 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji3 Q 3.35 BS02 MG Q 1 D13 M15 E49 D12 M14 E48 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji3 R 3.35 BS01 NUC A 1 K49 I50 P52 R53 K61 Q63 R64 K68 K71 R72 R74 I75 F81 K31 I32 P34 R35 K43 Q45 R46 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji3 S 3.35 BS01 NUC A 1 P2 S4 L5 K6 K7 F10 H14 K32 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 T79 Y80 P1 S3 L4 K5 K6 F9 H13 K31 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 T78 Y79 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji3 T 3.35 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 R25 N26 K27 K29 S31 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R86 K87 R89 G101 G102 G103 L104 S105 A106 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 R18 N19 K20 K22 S24 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R79 K80 R82 G94 G95 G96 L97 S98 A99 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji4 B 3.69 BS01 NUC A 1 R21 R23 P26 E35 G38 R96 L98 G99 G100 T103 N104 T107 R111 K132 R144 I172 E176 K179 R15 R17 P20 E29 G32 R90 L92 G93 G94 T97 N98 T101 R105 K126 R138 I166 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji4 B 3.69 BS02 MG B 1 E20 D189 D191 D205 D206 E14 D183 D185 D199 D200 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji4 C 3.69 BS01 NUC A 1 G2 N3 K4 I5 F10 R126 R127 S154 G155 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 L188 T191 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 R125 R126 S153 G154 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 L187 T190 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji4 C 3.69 BS02 MG C 1 A129 V130 R131 I157 A128 V129 R130 I156 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji4 D 3.69 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 R59 Q62 R66 E72 R73 Q74 N77 K84 K85 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 S137 Y138 L155 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 R58 Q61 R65 E71 R72 Q73 N76 K83 K84 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 S136 Y137 L154 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji4 D 3.69 BS02 ZN D 1 C9 C12 K22 C26 C31 C8 C11 K21 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji4 D 3.69 BS03 MG D 1 W173 R187 W172 R186 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji4 D 3.69 BS04 MG D 2 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji4 E 3.69 BS01 NUC A 1 R14 T16 A17 R18 M19 A21 G22 R24 R25 R27 K47 K57 Y60 Y61 A86 K92 A94 A95 T98 I101 A102 R107 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 A17 G18 R20 R21 R23 K43 K53 Y56 Y57 A82 K88 A90 A91 T94 I97 A98 R103 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji4 F 3.69 BS01 NUC A 1 R2 Y4 Y50 K54 V72 N73 R77 R80 R87 M89 V90 V91 K92 R2 Y4 Y50 K54 V72 N73 R77 R80 R87 M89 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji4 F 3.69 BS02 MG F 1 R80 R82 V85 R80 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji4 G 3.69 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 G82 R94 R95 S98 R102 N109 R114 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 G81 R93 R94 S97 R101 N108 R113 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji4 H 3.69 BS01 NUC A 1 M1 L2 T3 P5 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 K98 S113 T114 S115 G130 E132 M1 L2 T3 P5 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 K98 S113 T114 S115 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji4 I 3.69 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 R20 Y36 Q38 G39 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 K116 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 R19 Y35 Q37 G38 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 K115 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji4 I 3.69 BS02 MG I 1 V108 V109 V107 V108 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji4 J 3.69 BS01 NUC A 1 R5 K7 H13 S35 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 P53 F54 K55 H56 K57 S59 R60 E61 H62 H68 R70 D73 E97 K99 R3 K5 H11 S33 P35 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 P51 F52 K53 H54 K55 S57 R58 E59 H60 H66 R68 D71 E95 K97 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji4 J 3.69 BS02 MG J 1 K57 R60 K55 R58 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji4 K 3.69 BS01 NUC A 1 Y20 N26 N27 T31 D36 G37 N38 P39 W42 S44 G45 G46 V47 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 N16 N17 T21 D26 G27 N28 P29 W32 S34 G35 G36 V37 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji4 L 3.69 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K17 V18 R19 S22 K23 V24 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 L52 R53 K54 T61 Y69 G72 E73 R86 K91 D92 L94 R97 V101 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K13 V14 R15 S18 K19 V20 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 L48 R49 K50 T57 Y65 G68 E69 R82 K87 D88 L90 R93 V97 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLLGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji4 M 3.69 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 V74 N77 I78 Y87 R88 R91 H92 R94 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 V73 N76 I77 Y86 R87 R90 H91 R93 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji4 N 3.69 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K11 K15 F16 K17 V18 R19 Y21 T22 R23 R26 C27 R29 A30 R31 S32 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K10 K14 F15 K16 V17 R18 Y20 T21 R22 R25 C26 R28 A29 R30 S31 R34 R40 I41 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji4 N 3.69 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji4 O 3.69 BS01 NUC A 1 P2 K8 Q9 F18 D21 T22 G23 S24 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 Q62 R64 R65 R68 Y69 R72 E73 P1 K7 Q8 F17 D20 T21 G22 S23 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 Q61 R63 R64 R67 Y68 R71 E72 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji4 P 3.69 BS01 NUC A 1 M1 K3 R5 L6 R8 F9 S11 K12 H13 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 I33 K35 Y38 P41 R42 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 R81 Q82 M1 K3 R5 L6 R8 F9 S11 K12 H13 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 I33 K35 Y38 P41 R42 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji4 Q 3.69 BS01 NUC A 1 P2 K3 K4 K14 M15 Q16 K17 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 I90 R91 R92 N94 Y95 S97 L98 S99 K100 P1 K2 K3 K13 M14 Q15 K16 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 I89 R90 R91 N93 Y94 S96 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji4 Q 3.69 BS02 MG Q 1 D13 M15 E49 D12 M14 E48 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji4 R 3.69 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 K68 K71 R72 R74 I75 F81 K31 I32 R35 A42 K43 Q45 R46 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji4 S 3.69 BS01 NUC A 1 P2 R3 S4 K6 K7 F10 H14 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 T79 Y80 R81 P1 R2 S3 K5 K6 F9 H13 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 T78 Y79 R80 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji4 T 3.69 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 K21 R22 R23 N26 K27 S31 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 R80 K81 S82 R83 M85 R86 R89 G101 G102 G103 S105 A106 L3 K7 R8 H9 R10 Q11 K14 R15 R16 N19 K20 S24 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 R73 K74 S75 R76 M78 R79 R82 G94 G95 G96 S98 A99 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji5 B 3.85 BS01 NUC A 1 P26 K27 R96 L98 G99 G100 T103 N104 T107 I108 Q110 R111 R144 Y148 I172 R175 E176 K179 P20 K21 R90 L92 G93 G94 T97 N98 T101 I102 Q104 R105 R138 Y142 I166 R169 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji5 C 3.85 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 R127 S154 G155 R156 E161 A163 W167 R172 V173 P174 L175 H176 T177 L178 R179 F186 L188 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 R126 S153 G154 R155 E160 A162 W166 R171 V172 P173 L174 H175 T176 L177 R178 F185 L187 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji5 D 3.85 BS01 NUC A 1 G2 R3 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 S71 E72 R73 Q74 N77 K84 K86 G87 S113 R115 Q116 R118 Q119 R122 H123 H125 R131 V133 D134 L135 P136 S137 Y138 K151 L155 E205 S208 R209 G1 R2 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 S70 E71 R72 Q73 N76 K83 K85 G86 S112 R114 Q115 R117 Q118 R121 H122 H124 R130 V132 D133 L134 P135 S136 Y137 K150 L154 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji5 D 3.85 BS02 ZN D 1 C9 C12 L21 C26 C31 C8 C11 L20 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji5 D 3.85 BS03 MG D 1 S83 K85 G87 T89 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji5 E 3.85 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 K57 Y61 F84 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 L123 S125 R126 N127 N130 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 K53 Y57 F80 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 L119 S121 R122 N123 N126 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji5 F 3.85 BS01 NUC A 1 R2 Y4 Y50 K54 N73 R87 V90 V91 K92 R2 Y4 Y50 K54 N73 R87 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji5 F 3.85 BS02 MG F 1 R80 R82 V85 R80 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji5 G 3.85 BS01 NUC A 1 A2 R3 R4 R5 A7 R10 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 G81 G82 Y85 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 R4 A6 R9 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 G80 G81 Y84 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji5 H 3.85 BS01 NUC A 1 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 R102 R105 S113 T114 S115 K116 V129 G130 E132 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 R102 R105 S113 T114 S115 K116 V129 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji5 I 3.85 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji5 J 3.85 BS01 NUC A 1 K7 H13 D17 Q33 S35 G36 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 L71 D73 K99 K5 H11 D15 Q31 S33 G34 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 L69 D71 K97 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji5 K 3.85 BS01 NUC A 1 R12 Y20 H22 N26 N27 I29 T31 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 K71 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 R126 R2 Y10 H12 N16 N17 I19 T21 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 K45 K61 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 R116 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji5 K 3.85 BS02 MG K 1 N26 G52 S53 K55 N16 G42 S43 K45 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji5 L 3.85 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K20 S22 K23 K28 G29 A30 P31 F32 R33 R34 K46 K47 N49 S50 L52 R53 K54 T61 Y69 G72 E73 L84 R86 G87 K91 D92 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K16 S18 K19 K24 G25 A26 P27 F28 R29 R30 K42 K43 N45 S46 L48 R49 K50 T57 Y65 G68 E69 L80 R82 G83 K87 D88 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji5 M 3.85 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 V74 N77 I78 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 V73 N76 I77 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji5 N 3.85 BS01 NUC A 1 A2 R3 K4 A5 L6 K15 F16 K17 V18 R19 Y21 T22 R23 C27 R29 A30 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 K14 F15 K16 V17 R18 Y20 T21 R22 C26 R28 A29 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji5 N 3.85 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji5 O 3.85 BS01 NUC A 1 P2 K8 Q9 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 Q62 R64 R65 R68 Y69 R72 P1 K7 Q8 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 Q61 R63 R64 R67 Y68 R71 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji5 P 3.85 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 H16 Y17 R18 D23 R25 K27 R28 G30 K31 I33 K35 Y38 P41 R42 K43 T44 K50 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 S11 K12 H13 H16 Y17 R18 D23 R25 K27 R28 G30 K31 I33 K35 Y38 P41 R42 K43 T44 K50 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji5 Q 3.85 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 R25 P28 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 L43 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 R72 K87 R91 N94 Y95 S97 L98 S99 K100 P1 K2 K3 S11 K13 M14 Q15 K16 T17 R24 P27 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 L42 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 R71 K86 R90 N93 Y94 S96 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji5 R 3.85 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 K31 I32 R35 A42 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji5 S 3.85 BS01 NUC A 1 P2 R3 S4 L5 K6 F10 H14 K18 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 T79 Y80 R81 P1 R2 S3 L4 K5 F9 H13 K17 W33 R35 R36 Y51 N52 G53 K54 K69 G71 E72 T76 R77 T78 Y79 R80 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji5 T 3.85 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 R25 N26 K27 A28 K29 S31 A32 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R86 K87 R89 G101 G102 G103 L104 S105 A106 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 R18 N19 K20 A21 K22 S24 A25 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R79 K80 R82 G94 G95 G96 L97 S98 A99 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji6 B 3.55 BS01 NUC A 1 P26 K27 R96 L98 G99 G100 T103 N104 I108 R111 R144 Y148 I172 R175 E176 K179 P20 K21 R90 L92 G93 G94 T97 N98 I102 R105 R138 Y142 I166 R169 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji6 B 3.55 BS02 MG B 1 R96 W97 R90 W91 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji6 B 3.55 BS03 MG B 2 D166 D191 D205 D160 D185 D199 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji6 C 3.55 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 K27 R127 K150 S154 G155 R156 E161 Q162 A163 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 K26 R126 K149 S153 G154 R155 E160 Q161 A162 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 R189 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji6 D 3.55 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K84 K86 G87 S113 R115 Q116 R118 Q119 R122 H123 H125 R131 R132 V133 D134 L135 P136 S137 Y138 R141 K151 L155 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K83 K85 G86 S112 R114 Q115 R117 Q118 R121 H122 H124 R130 R131 V132 D133 L134 P135 S136 Y137 R140 K150 L154 E204 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji6 D 3.55 BS02 ZN D 1 C9 C12 C26 C31 C8 C11 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji6 D 3.55 BS03 MG D 1 S83 K85 T89 S82 K84 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji6 D 3.55 BS04 MG D 2 R107 R114 R106 R113 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji6 E 3.55 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 A48 P49 K57 Y61 A86 K92 A94 A95 T98 I101 A102 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 A44 P45 K53 Y57 A82 K88 A90 A91 T94 I97 A98 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji6 E 3.55 BS02 MG E 1 E68 P70 E64 P66 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji6 F 3.55 BS01 NUC A 1 R2 Y4 K54 E69 N73 R87 V90 V91 K92 R2 Y4 K54 E69 N73 R87 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji6 F 3.55 BS02 MG F 1 R82 V85 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji6 G 3.55 BS01 NUC A 1 A2 R3 R4 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 I42 R76 R79 G81 G82 Y85 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 I41 R75 R78 G80 G81 Y84 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji6 H 3.55 BS01 NUC A 1 M1 L2 T3 P5 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 K98 R102 R105 S113 T114 S115 K116 G117 G128 V129 G130 E132 M1 L2 T3 P5 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 K98 R102 R105 S113 T114 S115 K116 G117 G128 V129 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji6 I 3.55 BS01 NUC A 1 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji6 J 3.55 BS01 NUC A 1 K7 R9 H13 Q33 S35 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 G52 P53 F54 K55 H56 K57 R60 H62 H68 R70 L71 D73 E97 K99 K5 R7 H11 Q31 S33 P35 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 G50 P51 F52 K53 H54 K55 R58 H60 H66 R68 L69 D71 E95 K97 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji6 K 3.55 BS01 NUC A 1 Y20 N26 N27 I29 T31 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 Y75 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 R126 Y10 N16 N17 I19 T21 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 K45 Y65 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 R116 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji6 K 3.55 BS02 MG K 1 Q104 V105 Q94 V95 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji6 L 3.55 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 S22 K23 K28 G29 A30 P31 F32 R33 R34 K46 K47 P48 N49 S50 L52 R53 K54 K57 T61 Y69 G72 E73 L84 R86 G87 V90 K91 D92 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 S18 K19 K24 G25 A26 P27 F28 R29 R30 K42 K43 P44 N45 S46 L48 R49 K50 K53 T57 Y65 G68 E69 L80 R82 G83 V86 K87 D88 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLLGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji6 M 3.55 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 V74 N77 I78 R88 R91 H92 L96 P97 V98 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 V73 N76 I77 R87 R90 H91 L95 P96 V97 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji6 N 3.55 BS01 NUC A 1 A2 R3 K4 A5 E8 K15 F16 K17 V18 R19 Y21 T22 R23 C27 R29 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 E7 K14 F15 K16 V17 R18 Y20 T21 R22 C26 R28 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji6 N 3.55 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji6 N 3.55 BS03 MG N 1 T22 A30 V33 T21 A29 V32 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji6 O 3.55 BS01 NUC A 1 P2 K8 T22 G23 S24 Q28 L31 R35 R38 H42 H46 K48 D49 H50 H51 S52 R54 G55 R64 R65 R68 Y69 P1 K7 T21 G22 S23 Q27 L30 R34 R37 H41 H45 K47 D48 H49 H50 S51 R53 G54 R63 R64 R67 Y68 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji6 P 3.55 BS01 NUC A 1 M1 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 R25 R26 K27 R28 G30 K31 I33 K35 Y38 P41 R42 K43 T44 T45 K50 W59 S61 G63 T67 T69 R72 R75 R81 Q82 M1 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 R25 R26 K27 R28 G30 K31 I33 K35 Y38 P41 R42 K43 T44 T45 K50 W59 S61 G63 T67 T69 R72 R75 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji6 Q 3.55 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 E24 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 L43 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 N94 Y95 S97 L98 S99 K100 P1 K2 K3 S11 K13 M14 Q15 K16 T17 E23 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 L42 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 N93 Y94 S96 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji6 R 3.55 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 K31 I32 R35 A42 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji6 S 3.55 BS01 NUC A 1 P2 R3 S4 L5 K6 F10 H14 W34 R36 R37 Y52 N53 G54 K55 K70 G72 T77 R78 T79 Y80 R81 P1 R2 S3 L4 K5 F9 H13 W33 R35 R36 Y51 N52 G53 K54 K69 G71 T76 R77 T78 Y79 R80 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji6 T 3.55 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 A28 K29 S31 A32 T35 L36 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R86 K87 R89 G101 G102 G103 L104 S105 A106 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 A21 K22 S24 A25 T28 L29 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R79 K80 R82 G94 G95 G96 L97 S98 A99 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji7 B 3.50 BS01 NUC A 1 K22 W24 R96 L98 G99 G100 T103 N104 T107 I108 R111 R144 Y148 I172 R175 E176 K179 K16 W18 R90 L92 G93 G94 T97 N98 T101 I102 R105 R138 Y142 I166 R169 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji7 B 3.50 BS02 MG B 1 R96 L98 R90 L92 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji7 B 3.50 BS03 MG B 2 E20 K74 D166 D191 D205 E14 K68 D160 D185 D199 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji7 B 3.50 BS04 MG B 3 P194 V197 P188 V191 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji7 C 3.50 BS01 NUC A 1 G2 N3 K4 I5 F10 I14 K26 K27 R127 S154 G155 R156 E161 A163 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 L188 T191 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 I13 K25 K26 R126 S153 G154 R155 E160 A162 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 L187 T190 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji7 D 3.50 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 L21 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K84 K85 K86 G87 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 K151 L155 E156 E205 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 L20 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K83 K84 K85 G86 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 K150 L154 E155 E204 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji7 D 3.50 BS02 ZN D 1 C9 C12 C26 C31 C8 C11 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji7 D 3.50 BS03 MG D 1 A82 S83 K85 G87 T89 A81 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji7 E 3.50 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y61 F84 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y57 F80 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 S121 R122 N123 I125 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji7 F 3.50 BS01 NUC A 1 R2 Y4 Y50 K54 V72 N73 R80 R87 V90 V91 K92 R2 Y4 Y50 K54 V72 N73 R80 R87 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji7 G 3.50 BS01 NUC A 1 A2 R3 R4 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R79 G81 Y85 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R78 G80 Y84 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji7 H 3.50 BS01 NUC A 1 M1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 R105 S113 T114 S115 G128 G130 E132 M1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 R105 S113 T114 S115 G128 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji7 I 3.50 BS01 NUC A 1 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 G39 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 G38 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji7 J 3.50 BS01 NUC A 1 R5 K7 H13 S35 P37 I38 P39 L40 P41 T42 R43 V44 R46 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 L71 D73 K99 R3 K5 H11 S33 P35 I36 P37 L38 P39 T40 R41 V42 R44 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 L69 D71 K97 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji7 K 3.50 BS01 NUC A 1 R12 Y20 H22 N26 N27 I29 T31 D36 G37 N38 P39 I40 W42 S44 G46 V47 K51 G52 S53 K55 Y75 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 R2 Y10 H12 N16 N17 I19 T21 D26 G27 N28 P29 I30 W32 S34 G36 V37 K41 G42 S43 K45 Y65 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji7 L 3.50 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 V18 K21 S22 K28 G29 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 T61 Y69 G72 E73 R86 G87 V90 K91 D92 W94 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 V14 K17 S18 K24 G25 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 G68 E69 R82 G83 V86 K87 D88 W90 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLWGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji7 M 3.50 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 V74 N77 I78 Y87 R88 R91 H92 L96 P97 V98 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 V73 N76 I77 Y86 R87 R90 H91 L95 P96 V97 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji7 N 3.50 BS01 NUC A 1 A2 R3 K4 A5 L6 K15 F16 K17 V18 R19 Y21 T22 R23 C27 R29 A30 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 K14 F15 K16 V17 R18 Y20 T21 R22 C26 R28 A29 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji7 N 3.50 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji7 N 3.50 BS03 MG N 1 T22 A30 V33 T21 A29 V32 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji7 O 3.50 BS01 NUC A 1 P2 K8 Q9 I12 F18 D21 T22 G23 Q28 L31 R35 R38 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 M58 R64 R65 L66 R68 Y69 R72 P1 K7 Q8 I11 F17 D20 T21 G22 Q27 L30 R34 R37 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 M57 R63 R64 L65 R67 Y68 R71 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji7 P 3.50 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 Y38 P41 R42 K43 T45 Y58 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 Y38 P41 R42 K43 T45 Y58 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji7 Q 3.50 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 N94 Y95 L98 S99 K100 P1 K2 K3 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 N93 Y94 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji7 R 3.50 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 K68 K71 R72 R74 I75 F81 K31 I32 R35 A42 K43 Q45 R46 K50 K53 R54 R56 I57 F63 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji7 S 3.50 BS01 NUC A 1 P2 R3 S4 L5 K6 K7 F10 H14 K18 W34 R36 R37 Y52 G54 K55 K70 G72 E73 T77 R78 T79 Y80 R81 P1 R2 S3 L4 K5 K6 F9 H13 K17 W33 R35 R36 Y51 G53 K54 K69 G71 E72 T76 R77 T78 Y79 R80 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji7 T 3.50 BS01 NUC A 1 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 A28 K29 S31 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 K87 R89 G101 G102 G103 L104 S105 A106 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 A21 K22 S24 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 K80 R82 G94 G95 G96 L97 S98 A99 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4ji8 B 3.74 BS01 NUC A 1 K22 W24 R96 L98 G99 G100 T103 N104 T107 I108 Q110 R111 H140 R144 Y148 I172 E176 K179 K16 W18 R90 L92 G93 G94 T97 N98 T101 I102 Q104 R105 H134 R138 Y142 I166 E170 K173 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji8 B 3.74 BS02 MG B 1 R96 L98 R90 L92 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji8 B 3.74 BS03 MG B 2 K74 D166 D191 D205 K68 D160 D185 D199 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji8 B 3.74 BS04 MG B 3 P194 V197 P188 V191 P80371 24152548 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4ji8 C 3.74 BS01 NUC A 1 G2 N3 K4 I5 F10 I14 K26 R127 S154 G155 R156 G159 E161 Q162 A163 G171 R172 V173 P174 L175 H176 T177 L178 R179 F186 L188 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 I13 K25 R126 S153 G154 R155 G158 E160 Q161 A162 G170 R171 V172 P173 L174 H175 T176 L177 R178 F185 L187 T191 Y192 G193 V194 G196 K198 P80372 24152548 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4ji8 D 3.74 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 L21 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 S71 E72 R73 Q74 N77 K84 K86 G87 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 Y138 R141 K151 L155 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 L20 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 S70 E71 R72 Q73 N76 K83 K85 G86 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 Y137 R140 K150 L154 S207 R208 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji8 D 3.74 BS02 ZN D 1 C9 C12 K22 C26 C31 C8 C11 K21 C25 C30 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji8 D 3.74 BS03 MG D 1 S83 K85 G87 T89 S82 K84 G86 T88 P80373 24152548 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4ji8 E 3.74 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 K57 Y61 R64 A86 K92 A95 T98 I101 A102 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 K53 Y57 R60 A82 K88 A91 T94 I97 A98 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 24152548 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKG 4ji8 F 3.74 BS01 NUC A 1 R2 Y4 Y50 K54 N73 R77 R87 M89 V90 V91 K92 R2 Y4 Y50 K54 N73 R77 R87 M89 V90 V91 K92 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji8 F 3.74 BS02 MG F 1 R82 V85 R82 V85 Q5SLP8 24152548 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4ji8 G 3.74 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 G81 G82 Y85 R94 R95 S98 R102 N109 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 G80 G81 Y84 R93 R94 S97 R101 N108 R113 R114 A115 R118 W155 P17291 24152548 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4ji8 H 3.74 BS01 NUC A 1 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 K98 R105 S113 T114 S115 G128 G130 E132 M1 L2 T3 D4 A7 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 K98 R105 S113 T114 S115 G128 G130 E132 Q5SHQ2 24152548 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4ji8 I 3.74 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 G39 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 G38 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 24152548 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4ji8 J 3.74 BS01 NUC A 1 R5 K7 H13 Q33 S35 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 K99 R3 K5 H11 Q31 S33 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 K97 Q5SHN7 24152548 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4ji8 K 3.74 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 D36 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 R54 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 Y10 H12 N16 N17 I19 T21 D26 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 R44 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P80376 24152548 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4ji8 L 3.74 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K17 V18 K21 S22 K23 K28 G29 A30 P31 F32 R33 R34 K46 P48 N49 S50 A51 L52 R53 K54 T61 Y69 G72 E73 L84 R86 G87 K91 D92 W94 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K13 V14 K17 S18 K19 K24 G25 A26 P27 F28 R29 R30 K42 P44 N45 S46 A47 L48 R49 K50 T57 Y65 G68 E69 L80 R82 G83 K87 D88 W90 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 F6DEQ7 24152548 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLWGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEA 4ji8 M 3.74 BS01 NUC A 1 K13 R14 V17 Y23 G24 I25 G26 A28 R29 R44 V74 N77 L81 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y22 G23 I24 G25 A27 R28 R43 V73 N76 L80 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 24152548 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAG 4ji8 N 3.74 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K15 F16 K17 V18 R19 Y21 T22 R23 C27 R29 A30 R31 S32 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K14 F15 K16 V17 R18 Y20 T21 R22 C26 R28 A29 R30 S31 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji8 N 3.74 BS02 ZN N 1 C24 C27 C40 C43 C23 C26 C39 C42 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji8 N 3.74 BS03 MG N 1 T22 A30 V33 T21 A29 V32 Q5SHQ1 24152548 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4ji8 O 3.74 BS01 NUC A 1 P2 K5 K8 Q9 F18 D21 T22 G23 S24 T25 Q28 L31 R35 R38 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 L57 G61 Q62 R65 L66 R68 Y69 R72 P1 K4 K7 Q8 F17 D20 T21 G22 S23 T24 Q27 L30 R34 R37 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 L56 G60 Q61 R64 L65 R67 Y68 R71 Q5SJ76 24152548 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIR 4ji8 P 3.74 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 K35 Y38 P41 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 I33 K35 Y38 P41 K43 T44 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 24152548 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4ji8 Q 3.74 BS01 NUC A 1 P2 K3 K4 S12 K14 M15 Q16 K17 T18 E24 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 L43 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 I90 R91 N94 Y95 S97 L98 S99 K100 P1 K2 K3 S11 K13 M14 Q15 K16 T17 E23 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 L42 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 I89 R90 N93 Y94 S96 L97 S98 K99 Q5SHP7 24152548 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4ji8 R 3.74 BS01 NUC A 1 K49 I50 R53 A60 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 T82 K31 I32 R35 A42 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 T64 Q5SLQ0 24152548 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4ji8 S 3.74 BS01 NUC A 1 P2 R3 S4 L5 K6 K7 F10 H14 W34 R36 R37 Y52 N53 G54 K55 G72 E73 T77 R78 T79 Y80 P1 R2 S3 L4 K5 K6 F9 H13 W33 R35 R36 Y51 N52 G53 K54 G71 E72 T76 R77 T78 Y79 Q5SHP2 24152548 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4ji8 T 3.74 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 R22 R23 N26 K27 A28 K29 S31 A32 T35 L36 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R86 K87 R89 G101 G102 G103 L104 S105 A106 L3 K7 R8 H9 R10 Q11 S12 R15 R16 N19 K20 A21 K22 S24 A25 T28 L29 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R79 K80 R82 G94 G95 G96 L97 S98 A99 P80380 24152548 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4kh4 A 3.00 BS01 ANP A 1 G72 S73 S74 R77 R108 T188 A189 E236 G279 G280 A281 S282 G38 S39 S40 R43 R74 T154 A155 E202 G245 G246 A247 S248 3.6.1.15 Q27895 24115522 DADTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh4 A 3.00 BS02 MG A 1 E236 W600 E202 W563 3.6.1.15 Q27895 24115522 DADTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh4 B 3.00 BS01 ANP B 1 G72 S73 S74 R77 R108 T188 A189 E236 G279 G280 S282 M329 A330 R492 E493 G36 S37 S38 R41 R72 T152 A153 E200 G243 G244 S246 M293 A294 R456 E457 3.6.1.15 Q27895 24115522 DTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh4 B 3.00 BS02 MG B 1 D70 W600 D34 W564 3.6.1.15 Q27895 24115522 DTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh5 A 3.00 BS01 AU1 A 1 G72 S73 S74 R77 T188 A189 G279 G280 A281 S282 G38 S39 S40 R43 T154 A155 G245 G246 A247 S248 3.6.1.15 Q27895 24115522 DADTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh5 B 3.00 BS01 AU1 B 1 G72 S73 S74 R77 R108 T188 A189 E236 G279 G280 A281 S282 R492 E493 G36 S37 S38 R41 R72 T152 A153 E200 G243 G244 A245 S246 R454 E455 3.6.1.15 Q27895 24115522 DTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh5 B 3.00 BS02 MG B 1 D70 R77 T188 W600 D34 R41 T152 W562 3.6.1.15 Q27895 24115522 DTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGREMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh6 A 2.40 BS01 AU1 A 1 S73 S74 R77 G280 M329 R492 G493 A496 L553 L557 S40 S41 R44 G247 M294 R457 G458 A461 L518 L522 3.6.1.15 Q27895 24115522 VDADTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGRGMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kh6 B 2.40 BS01 AU1 B 1 G72 S73 S74 R77 T188 A189 E236 G280 A281 S282 G39 S40 S41 R44 T155 A156 E203 G247 A248 S249 3.6.1.15 Q27895 24115522 VDADTEKRINVGKTHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKTRSCPNKGRSIDPDSIQLIREGKRFTGLRVVLEEWLDTYAGKDWESRPVDARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEEQKVQVKALGIPVMLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKHSRNDLAGVVEVGGASAQIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVRKNRLKPLATYCSVHNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSIIEGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTAPMFITGRGMLASIDTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTDGPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKSIAGPDGKPLADLGWQVGVILHHVLFTEEWGRTAYEAGYSHNLE 4kni A 1.80 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 24103428 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4kni A 1.80 BS02 E1E A 1 I91 Q92 H94 H96 H119 V121 F131 L141 V143 L198 T199 T200 W209 I88 Q89 H91 H93 H116 V118 F127 L137 V139 L194 T195 T196 W205 4.2.1.1 P00918 24103428 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4knj A 2.00 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 24103428 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4knj A 2.00 BS02 E1F A 1 H94 H96 H119 V121 F131 V135 L141 V143 L198 T199 T200 P202 W209 H91 H93 H116 V118 F127 V131 L137 V139 L194 T195 T196 P198 W205 4.2.1.1 P00918 24103428 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4knm A 1.90 BS01 ZN A 1 H96 H98 H121 H92 H94 H117 4.2.1.1 Q8N1Q1 24103428 LSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knm A 1.90 BS02 E1E A 1 H96 H98 H121 V123 F133 V134 V145 L200 T201 V202 P204 W211 H92 H94 H117 V119 F129 V130 V141 L196 T197 V198 P200 W207 4.2.1.1 Q8N1Q1 24103428 LSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knm B 1.90 BS01 ZN B 1 H96 H98 H121 H91 H93 H116 4.2.1.1 Q8N1Q1 24103428 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knm B 1.90 BS02 E1E B 1 H96 H98 H121 V123 F133 V134 A137 V145 L200 T201 V202 L206 W211 H91 H93 H116 V118 F128 V129 A132 V140 L195 T196 V197 L201 W206 4.2.1.1 Q8N1Q1 24103428 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knn B 1.40 BS01 ZN B 1 H96 H98 H121 H91 H93 H116 4.2.1.1 Q8N1Q1 24103428 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knn B 1.40 BS02 E1F B 1 R93 Q94 H96 H98 H121 V123 F133 V145 L200 T201 V202 V209 W211 R88 Q89 H91 H93 H116 V118 F128 V140 L195 T196 V197 V204 W206 4.2.1.1 Q8N1Q1 24103428 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knn A 1.40 BS01 ZN A 1 H96 H98 H121 H91 H93 H116 4.2.1.1 Q8N1Q1 24103428 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4knn A 1.40 BS02 E1F A 1 H96 H98 H121 V123 F133 V145 L200 T201 V202 P204 W211 H91 H93 H116 V118 F128 V140 L195 T196 V197 P199 W206 4.2.1.1 Q8N1Q1 24103428 SWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 4kom A 2.60 BS01 SIA A 1 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 L217 Y86 G122 A123 T124 S125 W140 L142 H172 E179 L183 L215 24009358 ICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4kon A 2.60 BS01 SIA A 1 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L217 Y86 G122 A123 T124 S125 W140 L142 H172 E179 L215 24009358 ICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4kp5 A 1.45 BS01 ZN A 1 H91 H93 H117 H89 H91 H115 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp5 A 1.45 BS02 E1F A 1 H91 H93 H117 V119 S133 V141 L197 T198 T199 P201 V206 W208 H89 H91 H115 V117 S131 V139 L195 T196 T197 P199 V204 W206 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp5 B 1.45 BS01 ZN B 1 H91 H93 H117 H89 H91 H115 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp5 B 1.45 BS02 E1F B 1 H91 H93 H117 S133 V141 L197 T198 T199 P201 N203 V206 W208 H89 H91 H115 S131 V139 L195 T196 T197 P199 N201 V204 W206 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp5 C 1.45 BS01 ZN C 1 H91 H93 H117 H89 H91 H115 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4kp5 C 1.45 BS02 E1F C 1 Q89 H91 H93 H117 V119 S133 V141 L197 T198 T199 P201 V206 W208 Q87 H89 H91 H115 V117 S131 V139 L195 T196 T197 P199 V204 W206 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4kp5 D 1.45 BS01 ZN D 1 H91 H93 H117 H89 H91 H115 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4kp5 D 1.45 BS02 E1F D 1 H91 H93 H117 V119 S130 S133 L139 V141 L197 T198 P201 V206 W208 H89 H91 H115 V117 S128 S131 L137 V139 L195 T196 P199 V204 W206 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4kp8 A 1.80 BS01 ZN A 1 H91 H93 H117 H89 H91 H115 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp8 A 1.80 BS02 E1G A 1 Q89 H91 H93 H117 V119 S133 L197 T198 T199 P201 W208 Q87 H89 H91 H115 V117 S131 L195 T196 T197 P199 W206 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp8 B 1.80 BS01 ZN B 1 H91 H93 H117 H88 H90 H114 4.2.1.1 O43570 24103428 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4kp8 B 1.80 BS02 E1G B 1 Q89 H91 H93 H117 V119 S133 L197 T198 T199 P201 W208 Q86 H88 H90 H114 V116 S130 L194 T195 T196 P198 W205 4.2.1.1 O43570 24103428 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS 4kp8 C 1.80 BS01 ZN C 1 H91 H93 H117 H89 H91 H115 4.2.1.1 O43570 24103428 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp8 D 1.80 BS01 ZN D 1 H91 H93 H117 H88 H90 H114 4.2.1.1 O43570 24103428 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kp8 D 1.80 BS02 E1G D 1 Q89 H91 H93 H117 V119 S133 L197 T198 T199 P201 Q86 H88 H90 H114 V116 S130 L194 T195 T196 P198 4.2.1.1 O43570 24103428 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ 4kqo A 2.31 BS01 JPP A 1 S294 Y328 V333 S349 N351 Y409 S485 G486 T487 A488 R489 Y498 S245 Y279 V284 S300 N302 Y360 S436 G437 T438 A439 R440 Y449 G3XD46 23899657 ARSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPT 4kqo B 2.31 BS01 JPP B 1 S294 Y328 V333 S349 N351 Y409 K484 S485 G486 T487 R489 Y498 S221 Y255 V260 S276 N278 Y336 K411 S412 G413 T414 R416 Y425 G3XD46 23899657 IPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPTA 4kqq A 2.10 BS01 VPP A 1 S294 K297 V333 S349 N351 T404 Y407 Y409 S485 G486 T487 R489 Y498 Y503 F533 G534 G535 S244 K247 V283 S299 N301 T354 Y357 Y359 S435 G436 T437 R439 Y448 Y453 F483 G484 G485 G3XD46 23899657 RSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPTATEQQQVN 4kqq B 2.10 BS01 VPP B 1 S294 K297 Y328 V333 S349 N351 T404 Y407 Y409 S485 G486 T487 A488 R489 Y498 Y503 F533 G534 G535 S223 K226 Y257 V262 S278 N280 T333 Y336 Y338 S414 G415 T416 A417 R418 Y427 Y432 F462 G463 G464 G3XD46 23899657 AIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPTATEQQQVN 4kqr A 2.01 BS01 VPP A 1 S294 V333 S349 N351 T404 Y407 Y409 S485 G486 T487 R489 Y498 Y503 F533 G534 G535 S244 V283 S299 N301 T354 Y357 Y359 S435 G436 T437 R439 Y448 Y453 F483 G484 G485 G3XD46 23899657 RSVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPTATEQQQVN 4kqr B 2.01 BS01 VPP B 1 S294 V333 S349 N351 T404 Y407 Y409 S485 G486 T487 R489 Y498 Y503 F533 G534 G535 S242 V281 S297 N299 T352 Y355 Y357 S433 G434 T435 R437 Y446 Y451 F481 G482 G483 G3XD46 23899657 VRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAAALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEFRRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRRGRVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSMSAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSNVGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAETATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISPEVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVSVGTKGYRENAYRSLFAGFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPDNLPTATEQQQVN 4l4z A 2.30 BS01 D5X A 1 F124 G125 E126 A127 I210 G211 T220 I221 D243 L245 K288 F56 G57 E58 A59 I142 G143 T152 I153 D175 L177 K220 P76141 24047255 EGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l4z B 2.30 BS01 D5X B 1 F124 G125 E126 A127 I210 G211 T220 I221 D243 L245 G246 K288 F57 G58 E59 A60 I143 G144 T153 I154 D176 L178 G179 K221 P76141 24047255 FEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l50 A 2.10 BS01 D8X A 1 F124 G125 E126 A127 L176 I210 G211 T220 I221 Y226 D243 L245 G246 K288 F55 G56 E57 A58 L107 I141 G142 T151 I152 Y157 D174 L176 G177 K219 P76141 24047255 FEGCLEYETQLRRQFSLQHVRVIPGLADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l50 B 2.10 BS01 D8X B 1 F124 G125 E126 A127 L176 I210 G211 T220 I221 D243 L245 G246 K288 F54 G55 E56 A57 L106 I140 G141 T150 I151 D173 L175 G176 K218 P76141 24047255 EGCLEYETQLRRQFSLQHVRVIPGDADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l51 A 1.90 BS01 HSX A 1 F124 G125 E126 A127 G209 I210 G211 T220 I221 D243 I244 L245 K288 F53 G54 E55 A56 G138 I139 G140 T149 I150 D172 I173 L174 K217 P76141 24047255 EGCLEYETQLRRQFSLQHVRVIPGLDVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l51 B 1.90 BS01 HSX B 1 F124 G125 E126 A127 G209 G211 T220 D243 I244 L245 K288 F55 G56 E57 A58 G140 G142 T151 D174 I175 L176 K219 P76141 24047255 FEGCLEYETQLRRQFSLQHVRVIPGLADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l5j A 2.60 BS01 HSX A 1 F124 G125 E126 A127 G209 T220 I221 D243 L245 K288 F115 G116 E117 A118 G200 T211 I212 D234 L236 K279 P76141 24047255 EQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l5j B 2.60 BS01 HSX B 1 F124 G125 E126 A127 G209 I210 G211 T220 I221 D243 L245 K288 F115 G116 E117 A118 G200 I201 G202 T211 I212 D234 L236 K279 P76141 24047255 EQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l5j C 2.60 BS01 HSX C 1 F124 G125 E126 A127 G209 T220 I221 D243 L245 K288 F115 G116 E117 A118 G200 T211 I212 D234 L236 K279 P76141 24047255 EQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l5j D 2.60 BS01 HSX D 1 F124 G125 E126 A127 G209 I210 G211 T220 I221 D243 I244 L245 K288 F115 G116 E117 A118 G200 I201 G202 T211 I212 D234 I235 L236 K279 P76141 24047255 EQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS 4l6t A 1.86 BS01 ZN A 1 H179 H183 H189 H150 H154 H160 3.4.24.- Q8GAV4 24095060 AERTPNEEKKVIGYADHNGQLYNITSIYGPVINYTVPDENITINTINRTQLTINYSDYVREAFNEWAPSGIRVQQVSSRVVSFSTTNYADNSLGSTIFDPSGNSRTRIDIGSFNRIVMNNFEKLKSRGAIPANMSPEEYIKLKLRITIKHEIGHILGLLHNNEGGSYFPHGVGLEVARCRLLNQAPSIMLNGSNYDYIDRLSHYLERPVTETDIGPSRNDIEGVRVMRRGGSGNSFTNRFSCLGLGLAF 4l6t B 1.86 BS01 GAL B 1 E73 Q78 H79 Q83 W110 N112 K113 E52 Q57 H58 Q62 W89 N91 K92 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t B 1.86 BS02 SIA B 1 E33 Y34 Q35 L80 E12 Y13 Q14 L59 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t C 1.86 BS01 GAL C 1 E73 Q78 H79 Q83 W110 N112 K113 E52 Q57 H58 Q62 W89 N91 K92 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t C 1.86 BS02 SIA C 1 E33 Y34 Q35 L80 E12 Y13 Q14 L59 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t D 1.86 BS01 SIA C 1 G55 K56 G34 K35 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t D 1.86 BS02 GAL D 1 E73 Q78 H79 Q83 W110 N112 K113 E52 Q57 H58 Q62 W89 N91 K92 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t D 1.86 BS03 SIA D 1 E33 Y34 Q35 L80 E12 Y13 Q14 L59 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t E 1.86 BS01 GAL E 1 E73 Q78 H79 Q83 W110 N112 K113 E52 Q57 H58 Q62 W89 N91 K92 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t E 1.86 BS02 SIA E 1 E33 Y34 Q35 L80 E12 Y13 Q14 L59 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t F 1.86 BS01 SIA E 1 G55 K56 G34 K35 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t F 1.86 BS02 GAL F 1 E73 Q78 H79 Q83 W110 N112 K113 E52 Q57 H58 Q62 W89 N91 K92 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4l6t F 1.86 BS03 SIA F 1 E33 Y34 Q35 L80 E12 Y13 Q14 L59 Q8GAV3 24095060 MTPQNITDLCNEYQNTMIYSLNKEIATYTESLAGKREMVIISFSNGATFQVEVPGSQHLESQKRPLERMKDTLRAAYFTGIKISKLCAWTNKSPNSIAAIELSNL 4lkg A 2.99 BS01 SIA A 1 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 24009358 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSSCRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARTQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYYSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkg A 2.99 BS02 GAL A 1 G216 Q217 G216 Q217 24009358 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSSCRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARTQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYYSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkg C 2.99 BS01 SIA C 1 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 24009358 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSSCRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARTQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYYSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkg E 2.99 BS01 SIA E 1 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 24009358 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSSCRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARTQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYYSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkh A 3.10 BS01 SIA A 1 Y88 G124 A125 T126 S127 L144 H174 E181 L185 Q217 Y88 G124 A125 T126 S127 L144 H174 E181 L185 Q217 24009358 DKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSSCRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKNPALIVWGIHHSGSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARTQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDADCEGDCYYSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkj A 2.80 BS01 SIA A 1 Y88 G124 A125 T126 S127 W142 L144 H174 L185 Q217 Y86 G122 A123 T124 S125 W140 L142 H172 L183 Q215 24009358 ICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkk A 2.49 BS01 SIA A 1 Y88 G124 A125 T126 S127 W142 L144 H174 E181 L185 Q217 Y86 G122 A123 T124 S125 W140 L142 H172 E179 L183 Q215 24009358 ICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lkk A 2.49 BS02 GAL A 1 G216 Q217 G214 Q215 24009358 ICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPE 4lmp A 1.95 BS01 6MD A 1 L197 D198 K203 S220 V239 L240 L249 L197 D198 K203 S220 V239 L240 L249 1.4.1.1 I6YEC9 MRVGIPTETKNNEFRVAITPAGVAELTRRGHEVLIQAGAGEGSAITDADFKAAGAQLVGTADQVWADADLLLKVKEPIAAEYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETVQTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVLVPGAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRPTTYDHPTFAVHDTLFYCVANMPASVPKTSTYALTNATMPYVLELADHGWRAACRSNPALAKGLSTHEGALLSERVATDLGVPFTEPASVLA 4lni A 2.58 BS01 P3S A 1 E132 E134 Y156 E189 V190 N240 G241 H245 R298 Y303 E304 A305 R316 R335 E131 E133 Y155 E188 V189 N239 G240 H244 R297 Y302 E303 A304 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni A 2.58 BS02 ADP A 1 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 R321 I328 S329 R331 E333 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 R320 I327 S328 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni A 2.58 BS03 MG A 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni A 2.58 BS04 MG A 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni A 2.58 BS05 MG A 3 E132 E196 D198 E131 E195 D197 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni A 2.58 BS06 P3S F 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni B 2.58 BS01 P3S A 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni B 2.58 BS02 P3S B 1 E132 E134 Y156 E189 V190 N240 G241 H245 R298 Y303 E304 R316 R335 E131 E133 Y155 E188 V189 N239 G240 H244 R297 Y302 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni B 2.58 BS03 ADP B 1 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 N256 R321 I328 R331 E333 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 N255 R320 I327 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni B 2.58 BS04 MG B 1 E132 E134 E189 E196 E131 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni B 2.58 BS05 MG B 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni B 2.58 BS06 MG B 3 E132 E196 D198 E131 E195 D197 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni C 2.58 BS01 P3S C 1 E132 E134 Y156 E189 V190 E196 N240 G241 G243 H245 R298 Y303 E304 R316 R335 E131 E133 Y155 E188 V189 E195 N239 G240 G242 H244 R297 Y302 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni C 2.58 BS02 ADP C 1 N128 E132 E184 D198 F199 K200 Y201 N247 S249 N256 R321 I328 R331 E333 N127 E131 E183 D197 F198 K199 Y200 N246 S248 N255 R320 I327 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni C 2.58 BS03 MG C 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni C 2.58 BS04 MG C 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni C 2.58 BS05 MG C 3 E132 E196 E131 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni D 2.58 BS01 P3S C 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni D 2.58 BS02 P3S D 1 E132 E134 Y156 E189 V190 E196 N240 G241 H245 R298 E304 A305 R316 R335 E131 E133 Y155 E188 V189 E195 N239 G240 H244 R297 E303 A304 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni D 2.58 BS03 ADP D 1 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 N256 R316 R321 I328 S329 R331 E333 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 N255 R315 R320 I327 S328 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni D 2.58 BS04 MG D 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni D 2.58 BS05 MG D 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni D 2.58 BS06 MG D 3 E132 E196 E131 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni E 2.58 BS01 P3S D 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni E 2.58 BS02 P3S E 1 E132 E134 Y156 E189 V190 N240 G241 H245 R298 Y303 E304 R316 R335 E131 E133 Y155 E188 V189 N239 G240 H244 R297 Y302 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni E 2.58 BS03 ADP E 1 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 R321 I328 R331 E333 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 R320 I327 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni E 2.58 BS04 MG E 1 E132 E134 E189 E196 E131 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni E 2.58 BS05 MG E 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni E 2.58 BS06 MG E 3 E132 E196 E131 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni F 2.58 BS01 P3S F 1 E132 E134 Y156 E189 V190 N240 G241 H245 R298 Y303 E304 R316 R335 E131 E133 Y155 E188 V189 N239 G240 H244 R297 Y302 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni F 2.58 BS02 ADP F 1 G130 E132 E184 D198 F199 K200 Y201 N247 S249 N256 R316 R321 I328 S329 R331 E333 G129 E131 E183 D197 F198 K199 Y200 N246 S248 N255 R315 R320 I327 S328 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni F 2.58 BS03 MG F 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni F 2.58 BS04 MG F 2 E132 H245 R321 E333 E131 H244 R320 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni F 2.58 BS05 MG F 3 E132 E196 D198 E131 E195 D197 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni G 2.58 BS01 P3S G 1 E132 E134 Y156 E189 V190 N240 G241 G243 H245 R298 E304 R316 R335 E131 E133 Y155 E188 V189 N239 G240 G242 H244 R297 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni G 2.58 BS02 ADP G 1 G130 E132 E184 E196 D198 F199 Y201 N247 S249 R321 I328 S329 R331 E333 G129 E131 E183 E195 D197 F198 Y200 N246 S248 R320 I327 S328 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni G 2.58 BS03 MG G 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni G 2.58 BS04 MG G 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni G 2.58 BS05 MG G 3 E132 E196 D198 E131 E195 D197 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni G 2.58 BS06 P3S H 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni H 2.58 BS01 P3S H 1 E132 E134 Y156 E189 V190 N240 G241 H245 R298 Y303 E304 R316 R335 E131 E133 Y155 E188 V189 N239 G240 H244 R297 Y302 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni H 2.58 BS02 ADP H 1 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 N256 R321 I328 S329 R331 E333 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 N255 R320 I327 S328 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni H 2.58 BS03 MG H 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni H 2.58 BS04 MG H 2 E132 H245 E333 R335 E131 H244 E332 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni H 2.58 BS05 MG H 3 E132 E196 E131 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni I 2.58 BS01 P3S I 1 E132 E134 Y156 E189 V190 N240 G241 G243 H245 R298 Y303 E304 A305 R316 R335 E131 E133 Y155 E188 V189 N239 G240 G242 H244 R297 Y302 E303 A304 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni I 2.58 BS02 ADP I 1 N128 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 R321 I328 R331 E333 N127 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 R320 I327 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni I 2.58 BS03 MG I 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni I 2.58 BS04 MG I 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni I 2.58 BS05 MG I 3 E132 E196 E131 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni I 2.58 BS06 P3S J 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni J 2.58 BS01 P3S J 1 E132 E134 Y156 E189 V190 N240 G241 G243 H245 R298 E304 R316 R335 E129 E131 Y153 E186 V187 N237 G238 G240 H242 R295 E301 R313 R332 6.3.1.2 P12425 YTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni J 2.58 BS02 ADP J 1 G130 E132 E184 D198 F199 K200 Y201 N247 S249 R321 I328 S329 R331 E333 G127 E129 E181 D195 F196 K197 Y198 N244 S246 R318 I325 S326 R328 E330 6.3.1.2 P12425 YTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni J 2.58 BS03 MG J 1 E134 E189 E196 E131 E186 E193 6.3.1.2 P12425 YTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni J 2.58 BS04 MG J 2 E132 H245 E333 E129 H242 E330 6.3.1.2 P12425 YTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni J 2.58 BS05 MG J 3 E132 E196 D198 E129 E193 D195 6.3.1.2 P12425 YTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni J 2.58 BS06 P3S K 1 D53 S56 D50 S53 6.3.1.2 P12425 YTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni K 2.58 BS01 P3S K 1 E132 E134 Y156 E189 V190 N240 G241 H245 R298 Y303 E304 A305 R316 R335 E131 E133 Y155 E188 V189 N239 G240 H244 R297 Y302 E303 A304 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni K 2.58 BS02 ADP K 1 G130 E132 E184 E196 D198 F199 K200 Y201 N247 S249 N256 R321 I328 R331 E333 G129 E131 E183 E195 D197 F198 K199 Y200 N246 S248 N255 R320 I327 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni K 2.58 BS03 MG K 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni K 2.58 BS04 MG K 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni K 2.58 BS05 MG K 3 E132 E196 D198 E131 E195 D197 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni K 2.58 BS06 P3S L 1 D53 S56 D52 S55 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni L 2.58 BS01 P3S L 1 E132 E134 Y156 E189 V190 N240 G241 G243 H245 R298 Y303 E304 R316 R335 E131 E133 Y155 E188 V189 N239 G240 G242 H244 R297 Y302 E303 R315 R334 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni L 2.58 BS02 ADP L 1 G130 E132 E184 D198 F199 K200 Y201 N247 S249 N256 R321 I328 R331 E333 G129 E131 E183 D197 F198 K199 Y200 N246 S248 N255 R320 I327 R330 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni L 2.58 BS03 MG L 1 E134 E189 E196 E133 E188 E195 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni L 2.58 BS04 MG L 2 E132 H245 E333 E131 H244 E332 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lni L 2.58 BS05 MG L 3 E132 E196 D198 E131 E195 D197 6.3.1.2 P12425 AKYTREDIEKLVKEENVKYIRLQFTDILGTIKNVEIPVSQLGKALDNKVMFDGSSIEGFVRIEESDMYLYPDLNTFVIFPWTAEKGKVARFICDIYNPDGTPFEGDPRNNLKRILKEMEDLGFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLAPTDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYAGAVRSCDDIQTFKLVVKTIARKHGLHATFMPKPLFGVNGSGMHCNLSLFKNGVNAFFDENADLQLSETAKHFIAGIVKHATSFTAVTNPTVNSYKRLVPGYEAPCYVAWSAQNRSPLIRIPASRGISTRVEVRSVDPAANPYLALSVLLAAGLDGIKNKLEAPAPIDRNIYVMSKEERMENGIVDLPATLAEALEEFKSNEVMVKALGEHLFEHFIEAKEIEWDMFRTQVHPWEREQYMSQY 4lnj A 2.10 BS01 MG A 1 T8 T10 S196 T201 T8 T10 S196 T201 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnj A 2.10 BS02 MG A 2 A93 V94 S97 A93 V94 S97 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnj A 2.10 BS03 PLR A 1 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnj B 2.10 BS01 MG A 3 A93 V94 S97 A93 V94 S97 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnj B 2.10 BS02 MG B 1 T8 T10 S196 T201 T8 T10 S196 T201 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnj B 2.10 BS03 PLR B 1 T57 G58 T59 H83 E136 D166 A168 R169 K197 T57 G58 T59 H83 E136 D166 A168 R169 K197 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl A 2.10 BS01 MG A 1 T8 T10 S196 T201 T8 T10 S196 T201 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl A 2.10 BS02 2BO A 1 S6 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 R308 S6 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 R308 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl A 2.10 BS03 2BK A 1 S6 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 R308 S6 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 R308 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl A 2.10 BS04 MG B 1 A93 V94 S97 A93 V94 S97 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl B 2.10 BS01 MG B 2 T8 T10 S196 T201 T8 T10 S196 T201 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl B 2.10 BS02 MG B 1 A93 V94 S97 A93 V94 S97 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnl B 2.10 BS03 PLG B 1 S6 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 R308 S6 T57 G58 T59 N62 H83 E136 D166 A168 R169 K197 R308 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLA 4lnm A 2.10 BS01 CA A 1 T8 T10 S196 T201 T8 T10 S196 T201 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFL 4lnm A 2.10 BS02 PLR A 1 T57 G58 T59 H83 E136 D166 A168 K197 T57 G58 T59 H83 E136 D166 A168 K197 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFL 4lnm A 2.10 BS03 CA A 2 A93 V94 S97 A93 V94 S97 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFL 4lnm B 2.10 BS01 PLG A 1 S6 T57 G58 T59 H83 E136 D166 A168 R169 K197 R308 S6 T57 G58 T59 H83 E136 D166 A168 R169 K197 R308 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFL 4lnm B 2.10 BS02 CA A 3 A93 V94 S97 A93 V94 S97 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFL 4lnm B 2.10 BS03 CA B 1 T8 T10 S196 T201 T8 T10 S196 T201 4.1.2.5 E7U392 24165453 MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALKNNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFL 4lrr A 2.41 BS01 CF9 A 1 E58 F62 W80 W83 Y94 L143 C146 H147 Q165 S167 C168 D169 G173 L174 N177 E58 F62 W80 W83 Y94 L143 C146 H147 Q165 S167 C168 D169 G173 L174 N177 2.1.1.45 P0A886 24147825 MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI 4lrr A 2.41 BS02 UMP A 1 R21 R166 R21 R166 2.1.1.45 P0A886 24147825 MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI 4lv7 A 2.60 BS01 IHP A 1 G19 G20 A21 R45 R130 K168 K170 H196 K200 N238 D368 D407 K411 R415 Y419 G17 G18 A19 R43 R116 K146 K148 H174 K178 N216 D333 D360 K364 R368 Y372 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKARRSVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 A 2.60 BS02 ADP A 1 R16 G17 E18 G19 G20 A21 N22 V24 V38 R40 N147 D148 H149 E166 R241 F243 M372 I406 D407 R14 G15 E16 G17 G18 A19 N20 V22 V36 R38 N133 D134 H135 E144 R219 F221 M337 I359 D360 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKARRSVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 A 2.60 BS03 MG A 1 R40 D407 S409 R38 D360 S362 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKARRSVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 A 2.60 BS04 ZN A 1 H320 C330 C333 H346 H295 C305 C308 H311 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKARRSVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 B 2.60 BS01 IHP B 1 G19 G20 A21 R130 K168 K170 H196 K200 N238 D368 D407 K411 R415 Y419 G17 G18 A19 R114 K146 K148 H174 K178 N216 D334 D364 K368 R372 Y376 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKASVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFSQDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSGHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQSRDYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 B 2.60 BS02 ADP B 1 R16 G17 E18 G19 G20 A21 N22 V24 V38 R40 N147 D148 H149 E166 M372 D407 R14 G15 E16 G17 G18 A19 N20 V22 V36 R38 N131 D132 H133 E144 M338 D364 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKASVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFSQDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSGHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQSRDYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 B 2.60 BS03 MG B 1 G19 D407 G17 D364 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKASVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFSQDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSGHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQSRDYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4lv7 B 2.60 BS04 ZN B 1 H320 C330 C333 H346 H296 C306 C309 H312 2.7.1.158 Q93YN9 MILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQKASVLTSDEQHLWRENNELISSPNKCVLEQRYVQNVIIPLLGPKHVDAGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDCALILNDHSLFSQDCISVEIKPKCGFLPTSRFIGKENILKTSVSRFKMHQLLKLEYIEISEESEYDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTSPEIGYAFEDALKGFIQSGHRTECFLQLVSDAVYGSGVLDRLLEIQKLDKLDIEGAIHCYYDIINQPCPICSLHALPLDESLKIVKEYLIAATAKDCSIMISFQSRDYVSLKPTNQTFDYKVHFIDLSLKPLKRMESYYKLDKKIISFYNRKQKAE 4m2r A 1.99 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 24090602 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2r A 1.99 BS02 BZ1 A 1 H64 Q92 H94 H96 H119 V121 F131 L198 T199 T200 W209 H61 Q89 H91 H93 H116 V118 F127 L194 T195 T196 W205 4.2.1.1 P00918 24090602 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2u A 2.00 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 24090602 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2u A 2.00 BS02 ETS A 1 W5 Q92 H94 H96 H119 V121 F131 L198 T199 T200 W209 W2 Q89 H91 H93 H116 V118 F127 L194 T195 T196 W205 4.2.1.1 P00918 24090602 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2v A 1.72 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 24090602 HWGYGAHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2v A 1.72 BS02 BZ1 A 1 Q92 H94 H96 H119 V121 V131 G132 L141 L198 T199 T200 W209 Q89 H91 H93 H116 V118 V127 G128 L137 L194 T195 T196 W205 4.2.1.1 P00918 24090602 HWGYGAHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2w A 1.66 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 24090602 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m2w A 1.66 BS02 ETS A 1 Q92 H94 H96 H119 V121 L141 L198 T199 T200 W209 Q89 H91 H93 H116 V118 L137 L194 T195 T196 W205 4.2.1.1 P00918 24090602 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHSFQVTFDDSQDKAVLKGGPLDGTYRLLQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTEGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLAECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4m9q A 2.50 BS01 GNP A 1 D28 N29 A30 G31 K32 T33 T34 T47 T50 G72 N128 K129 D131 L132 T160 A161 K162 D13 N14 A15 G16 K17 T18 T19 T31 T34 G56 N112 K113 D115 L116 T144 A145 K146 3.6.5.2 A8INQ0 GPRKITIALLGLDNAGKTTLLNSIQGEDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEARKKK 4m9q A 2.50 BS02 MG A 1 T33 T50 T18 T34 3.6.5.2 A8INQ0 GPRKITIALLGLDNAGKTTLLNSIQGEDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEARKKK 4m9q B 2.50 BS01 GNP B 1 D28 N29 A30 G31 K32 T33 T34 T47 T50 G71 G72 N128 K129 D131 L132 T160 A161 K162 D11 N12 A13 G14 K15 T16 T17 T30 T33 G54 G55 N111 K112 D114 L115 T143 A144 K145 3.6.5.2 A8INQ0 RKITIALLGLDNAGKTTLLNSIQGEVDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEARKKKER 4m9q B 2.50 BS02 MG B 1 T33 T50 T16 T33 3.6.5.2 A8INQ0 RKITIALLGLDNAGKTTLLNSIQGEVDRDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEARKKKER 4m9q C 2.50 BS01 GNP C 1 D28 N29 A30 G31 K32 T33 T34 T47 T50 G72 N128 K129 D131 T160 A161 K162 D13 N14 A15 G16 K17 T18 T19 T30 T33 G55 N111 K112 D114 T143 A144 K145 3.6.5.2 A8INQ0 GPRKITIALLGLDNAGKTTLLNSIQGERDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEAR 4m9q C 2.50 BS02 MG C 1 T33 T50 T18 T33 3.6.5.2 A8INQ0 GPRKITIALLGLDNAGKTTLLNSIQGERDTTPTFGFNSTTLNEGKYKIEVFDLGGGKNIRGVWKKYLAEVHAIVYVVDAADPGRFEESKMTMAEVLENQFMRDKPICIFANKQDLPTAAPAAEVVKGLGLATCRNSHNVFPCTAKMPAGQDVDHRLRDGLKWLVGTVDREFGRLDPRVQTEAEEVRQEEAR 4mbo A 1.65 BS01 CA A 1 D375 T408 D59 T92 Q8E473 MLGKDVSSELQKVNIALKDNTLSEPGTVKLDSSENLVLNFAFSIASVNEGDVFTVKLSDNLDTQGIGTILKVQDIMDETGQLLATGSYSPLTHNITYTWTRYASTLNNIKARVNMPVWPDQRIISKTTSDKQCFTATLNNQVASIEERVQYNSPSVTEHTNVKTNVRSRIMKLDDERQTETYITQINPEGKEMYFASGLGNLYTIIGSDGSPVNLLNAEVKILKTNSKNLTDSMDQNYDSPEFEDVTSQYSYTNDGSKITIDWKTNSISSTTSYVVLVKIPKQSGVLYSTVSDINQTYGSKYSYGHTN 4mde A 1.80 BS01 NUC C 1 S17 K21 S37 N38 R41 Q51 T52 T54 F58 H62 T80 Q83 A86 R123 Y128 V129 H133 S18 K22 S38 N39 R42 Q52 T53 T55 F59 H63 T81 Q84 A87 R124 Y129 V130 H134 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mde A 1.80 BS02 GDP A 1 G18 G20 K21 S22 T23 R116 R120 G19 G21 K22 S23 T24 R117 R121 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mde A 1.80 BS03 MG A 1 S22 R123 S23 R124 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mde B 1.80 BS01 NUC D 1 S17 K21 S37 N38 R41 Q51 T52 T54 F58 H62 T80 Q83 A86 R123 V125 Y128 V129 R131 K132 H133 S18 K22 S38 N39 R42 Q52 T53 T55 F59 H63 T81 Q84 A87 R124 V126 Y129 V130 R132 K133 H134 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mde B 1.80 BS02 GDP B 1 S16 G18 S19 G20 K21 S22 T23 R116 R120 S17 G19 S20 G21 K22 S23 T24 R117 R121 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mde B 1.80 BS03 MG B 1 S22 R123 S23 R124 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mdf A 1.73 BS01 NUC C 1 S37 N38 R41 Q51 T52 T54 F58 H62 T80 Q83 A86 R123 Y128 V129 H133 S38 N39 R42 Q52 T53 T55 F59 H63 T81 Q84 A87 R124 Y129 V130 H134 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mdf A 1.73 BS02 GTP A 1 S17 G18 S19 G20 K21 S22 T23 N38 R116 R120 R123 S18 G19 S20 G21 K22 S23 T24 N39 R117 R121 R124 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mdf B 1.73 BS01 NUC D 1 S37 N38 R41 Q51 T52 T54 F58 H62 A79 T80 Q83 A86 R123 V125 Y128 V129 R131 H133 S38 N39 R42 Q52 T53 T55 F59 H63 A80 T81 Q84 A87 R124 V126 Y129 V130 R132 H134 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mdf B 1.73 BS02 GTP B 1 S17 G18 S19 G20 K21 S22 T23 N38 R116 R120 R123 S18 G19 S20 G21 K22 S23 T24 N39 R117 R121 R124 A3DJ38 24150947 SMKLTIPELSLVVLIGSSGSGKSTFAKKHFKPTEVISSNFCRGLVSDDENDQTVTGAAFDVLHYIVSKRLQLGKLTVVDATNVQESARKPLIEIAKDYHCFPVAVVFNLPEKVCQERNKNRTDRQVEEYVIRKHTQQMKKSIKGLQREGFRYVYILNSPEEVEEVVFERQP 4mfb A 2.88 BS01 29T A 1 L100 K101 K102 K103 V106 V108 V179 Y181 Y188 V189 G190 F227 W229 P236 Y318 L97 K98 K99 K100 V103 V105 V176 Y178 Y185 V186 G187 F224 W226 P233 Y315 2.7.7.49 P03366 24151856 PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFAAQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQ 4mj0 A 1.70 BS01 SIA A 1 L62 L67 K68 N272 S274 T276 Q278 L31 L36 K37 N241 S243 T245 Q247 Q85235 24130487 VEVLEVKTGVDAITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSVK 4mj0 B 1.70 BS01 SIA B 1 L62 L67 K68 N272 S274 T276 Q278 L28 L33 K34 N238 S240 T242 Q244 Q85235 24130487 EVLEVKTDAITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSVKN 4mj0 B 1.70 BS02 SIA B 2 K68 S274 T276 K34 S240 T242 Q85235 24130487 EVLEVKTDAITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSVKN 4mj0 C 1.70 BS01 SIA C 1 L62 L67 K68 N272 S274 T276 Q278 L23 L28 K29 N224 S226 T228 Q230 Q85235 24130487 VLEVITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSV 4mj0 C 1.70 BS02 SIA C 2 K68 T276 K29 T228 Q85235 24130487 VLEVITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSV 4mj0 D 1.70 BS01 SIA D 1 L62 L67 K68 N272 S274 T276 Q278 L31 L36 K37 N241 S243 T245 Q247 Q85235 24130487 VEVLEVKTGVDAITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSVKNP 4mj0 D 1.70 BS02 SIA D 2 D59 L67 D28 L36 Q85235 24130487 VEVLEVKTGVDAITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPERKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGITSMLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGDPLEMQGVLMNYRTKYPDGTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENTRYFGTFTGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRGLARYFKIRLRKRSVKNP 4mj7 A 2.51 BS01 ZN A 1 C64 C89 H91 C102 C62 C87 H89 C100 Q12339 24152547 QKRAKSYRKQLLVYSHTFKFREPYQVLVDNQLVLECNNSNFNLPSGLKRTLQADVKVMITQCCIQALYETRNDGAINLAKQFERRRCNHSFKDPKSPAECIESVVNISGANKHRYVVASQDIDLRRKLRTVPGVPLIHLTRSVMVMEPLSTASAKAS 4mj7 B 2.51 BS01 ZN B 1 C64 C89 H91 C102 C62 C87 H89 C96 Q12339 24152547 QKRAKSYRKQLLVYSHTFKFREPYQVLVDNQLVLECNNSNFNLPSGLKRTLQADVKVMITQCCIQALYETRNDGAINLAKQFERRRCNHSKSPAECIESVVNISGANKHRYVVASQDIDLRRKLRTVPGVPLIHLTRSVMVMEPLSTASAKAS 4mjo A 2.40 BS01 2C1 A 1 V17 M18 G21 R22 R25 G26 G28 E29 L30 T31 M177 V9 M10 G13 R14 R17 G18 G20 E21 L22 T23 M161 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo A 2.40 BS02 2C1 C 1 T27 G28 T19 G20 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo B 2.40 BS01 2C1 B 1 V17 M18 E20 G21 R22 A24 R25 G26 G28 E29 L30 T31 V160 M177 V9 M10 E12 G13 R14 A16 R17 G18 G20 E21 L22 T23 V142 M159 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo B 2.40 BS02 2C1 D 1 T27 G28 T19 G20 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo C 2.40 BS01 2C1 C 1 M18 G21 R22 A24 R25 G26 G28 E29 L30 T31 M177 M10 G13 R14 A16 R17 G18 G20 E21 L22 T23 M159 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo D 2.40 BS01 2C1 B 1 T27 G28 T19 G20 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo D 2.40 BS02 2C1 D 1 V17 M18 E20 G21 R22 A24 R25 G26 G28 E29 L30 T31 M177 V9 M10 E12 G13 R14 A16 R17 G18 G20 E21 L22 T23 M160 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo E 2.40 BS01 2C1 E 1 V17 M18 G21 R22 A24 R25 G26 G28 E29 L30 T31 M177 V9 M10 G13 R14 A16 R17 G18 G20 E21 L22 T23 M161 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo F 2.40 BS01 2C1 F 1 V17 M18 G21 R22 A24 R25 G26 G28 E29 L30 T31 M177 V9 M10 G13 R14 A16 R17 G18 G20 E21 L22 T23 M159 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo F 2.40 BS02 2C1 H 1 T27 G28 T19 G20 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo G 2.40 BS01 2C1 G 1 V17 M18 G21 R22 R25 G26 T27 G28 E29 L30 T31 V9 M10 G13 R14 R17 G18 T19 G20 E21 L22 T23 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo H 2.40 BS01 2C1 F 1 T27 G28 T19 G20 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mjo H 2.40 BS02 2C1 H 1 V17 M18 G21 R22 A24 R25 G26 G28 E29 L30 T31 V160 M177 V9 M10 G13 R14 A16 R17 G18 G20 E21 L22 T23 V142 M159 3.1.3.11 P09467 24128068 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 4mpk A 2.65 BS01 NAG A 1 N39 I40 S41 W48 R84 N39 I40 S41 W48 R84 Q7YS85 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLWPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVTAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSYTLASSKTDVGAPISGPGIPGRFTKWKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSAIKDVLARV 4mpk A 2.65 BS02 NAG A 2 W10 R14 W78 T267 W331 L335 W10 R14 W78 T266 W330 L334 Q7YS85 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNTLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLWPGWRDKRHLTTLVKEMKAEFVREAQAGTEQLLLSAAVTAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSPLFRGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSYTLASSKTDVGAPISGPGIPGRFTKWKGILAYYEICDFLHGATTHRFRDQQVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSAIKDVLARV 4my0 A 2.10 BS01 ACO A 1 S25 F26 V85 V87 R92 G93 R94 G95 G97 S98 A121 T122 V124 I125 Y126 H128 S22 F23 V82 V84 R89 G90 R91 G92 G94 S95 A118 T119 V121 I122 Y123 H125 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 A 2.10 BS02 AC8 C 1 R148 R153 S245 I246 R145 R150 S242 I243 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 B 2.10 BS01 ACO B 1 S25 F26 V85 V87 R92 G93 R94 G95 G97 S98 A121 V124 I125 Y126 H128 S22 F23 V82 V84 R89 G90 R91 G92 G94 S95 A118 V121 I122 Y123 H125 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 B 2.10 BS02 ACO F 1 R148 S245 I246 R145 S242 I243 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 C 2.10 BS01 AC8 C 1 F26 V85 V87 R92 G93 R94 G95 G97 S98 A121 T122 V124 I125 Y126 F29 V88 V90 R95 G96 R97 G98 G100 S101 A124 T125 V127 I128 Y129 D2PVF8 SNAVTDDLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 C 2.10 BS02 ACO E 1 R148 S245 I246 R151 S248 I249 D2PVF8 SNAVTDDLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 D 2.10 BS01 ACO B 1 R148 S245 I246 R145 S242 I243 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 D 2.10 BS02 ACO D 1 S25 F26 V85 V87 R92 G93 R94 G95 G97 S98 A121 T122 V124 I125 Y126 H128 S22 F23 V82 V84 R89 G90 R91 G92 G94 S95 A118 T119 V121 I122 Y123 H125 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 E 2.10 BS01 ACO A 1 R148 S245 I246 R145 S242 I243 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 E 2.10 BS02 ACO E 1 S25 F26 V85 V87 R92 G93 R94 G95 G97 S98 A121 T122 V124 Y126 H128 S22 F23 V82 V84 R89 G90 R91 G92 G94 S95 A118 T119 V121 Y123 H125 D2PVF8 DLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 F 2.10 BS01 ACO D 1 R148 S245 I246 R146 S243 I244 D2PVF8 DDLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4my0 F 2.10 BS02 ACO F 1 S25 F26 V85 V87 R92 G93 R94 G95 G97 S98 A121 T122 V124 I125 Y126 H128 S23 F24 V83 V85 R90 G91 R92 G93 G95 S96 A119 T120 V122 I123 Y124 H126 D2PVF8 DDLRLVDITETQLDDVLRVRARSFGLLAAGAREDWVRDAVEFVHDGRFLGVVSGDEVVAAARIWDFQQWWGGRRVPMAGIAGVVVAPEYRGRGVGSLLMRGVLERSRDKGMPISALYPATTVIYRHLGYEFGGHRYRFSFQAADLRSLGGREVAVRRAGAKDAARFLELVGTAHEASRASGLLVWPESKIAEWLEDEENFAYLAEDGFVVYNWSDGDLQVDELVAHSEATARALWATVGSGASIARTVHAYLSPNDPVHLLVEHEADKQAHVQRWMLRLLDAPAAIAARGFAPGAAAEVDLLIDDPGVPAQSGRWHLSVADGTGELTPSDRSGDVLQLGSRGLAALYAGTPLAALRTAGLVTGGPVASDRLLDTAFGGAAPYMLDYF 4mza A 1.65 BS01 CA A 1 D279 S282 G284 A316 D139 S142 G144 A176 3.2.1.18 P08492 24149514 RITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCVRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASSGIEDIVLDIVNHDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENAICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGSEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTSTERVNELAIRNKTLSAGYTTTSCITHYNKGYCFHIVEINHKSLDTFQPMLFKTEIPKSCS 4mza B 1.65 BS01 CA B 1 D279 S282 S283 G284 A316 D144 S147 S148 G149 A181 3.2.1.18 P08492 24149514 EVPPQRITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCVRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASSGIEDIVLDIVNHDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENAICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGSEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTSTERVNELAIRNKTLSAGYTTTSCITHYNKGYCFHIVEINHKSLDTFQPMLFKTEIPKSCS 4mze A 1.80 BS01 CA A 1 D279 S282 S283 G284 A316 D139 S142 S143 G144 A176 3.2.1.18 P08492 24149514 RITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCVRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASSGIEDIVLDIVNHDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENAICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGSEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTSTERVNELAIRNKTLSAGYTTTSCITHYNKGYCFHIVEINQKSLDTFRPMLFKTEIPKSCS 4mze B 1.80 BS01 CA B 1 D279 S282 G284 I285 A316 D139 S142 G144 I145 A176 3.2.1.18 P08492 24149514 RITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCVRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASSGIEDIVLDIVNHDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENAICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGSEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTSTERVNELAIRNKTLSAGYTTTSCITHYNKGYCFHIVEINQKSLDTFRPMLFKTEIPKSCS 4mzj A 1.47 BS01 III T 1 Y97 R100 K101 G103 L104 A105 P106 H136 D139 L144 M147 H150 L168 W171 G172 D173 A174 L175 A183 F198 D201 I202 L203 Q204 Y35 R38 K39 G41 L42 A43 P44 H74 D77 L82 M85 H88 L106 W109 G110 D111 A112 L113 A121 F136 D139 I140 L141 Q142 Q8I4W8 ADIQQLEEKVDESDVRIYFNEKSSGGKISIDNASYNARKLGLAPSSIDEKKIKELYGDNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYKLFCEDILQ 4mzk A 1.82 BS01 III T 1 Y97 R100 L104 A105 P106 I109 H136 D139 E143 L144 F148 H150 L168 W171 G172 D173 A174 L175 F198 I202 L203 Y35 R38 L42 A43 P44 I47 H74 D77 E81 L82 F86 H88 L106 W109 G110 D111 A112 L113 F136 I140 L141 Q8I4W8 ADIQQLEEKVDESDVRIYFNEKSSGGKISIDNASYNARKLGLAPSSIDEKKIKELYGDNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYKLFCEDILQ 4mzl A 2.01 BS01 III C 1 Y97 R100 K101 G103 L104 A105 P106 I109 H136 D139 E143 L144 K146 M147 H150 I167 L168 W171 G172 D173 A174 L175 E179 A183 F198 I202 L203 Q204 Y31 R34 K35 G37 L38 A39 P40 I43 H70 D73 E77 L78 K80 M81 H84 I101 L102 W105 G106 D107 A108 L109 E113 A117 F132 I136 L137 Q138 Q8I4W8 QLEEKVDESDVRIYFNEKSSGGKISIDNASYNARKLGLAPSSIDEKKIKELYGDNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYKLFCEDILQ 4mzl B 2.01 BS01 III D 1 R100 G103 L104 A105 P106 I109 H136 D139 E143 L144 K146 M147 H150 L168 W171 G172 D173 A174 L175 E179 A183 D201 I202 L203 Q204 R34 G37 L38 A39 P40 I43 H70 D73 E77 L78 K80 M81 H84 L102 W105 G106 D107 A108 L109 E113 A117 D135 I136 L137 Q138 Q8I4W8 QLEEKVDESDVRIYFNEKSSGGKISIDNASYNARKLGLAPSSIDEKKIKELYGDNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNIDYKLFCEDILQ 4n0q A 2.30 BS01 LEU A 1 F40 V99 T100 T101 T122 A123 T124 Y172 Y224 E248 G249 F297 F17 V76 T77 T78 T99 A100 T101 Y149 Y201 E225 G226 F274 Q8YEE8 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSAANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRDGQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNAQGTLFTNAKDATKNPAAKDAIQALKAKNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSAAVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKWDDGKIVGL 4n0q B 2.30 BS01 LEU B 1 F40 V99 T100 T101 T122 A123 T124 Y172 Y224 E248 G249 F297 F18 V77 T78 T79 T100 A101 T102 Y150 Y202 E226 G227 F275 Q8YEE8 ADITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSAANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRDGQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNAQGTLFTNAKDATKNPAAKDAIQALKAKNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSAAVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKWDDGKIVGL 4n0q C 2.30 BS01 LEU C 1 F40 V99 T100 T101 T122 A123 T124 Y172 Y224 E248 G249 F297 F17 V76 T77 T78 T99 A100 T101 Y149 Y201 E225 G226 F274 Q8YEE8 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSAANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRDGQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNAQGTLFTNAKDATKNPAAKDAIQALKAKNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSAAVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKWDDGKIVGL 4n0q D 2.30 BS01 LEU D 1 F40 V99 T100 T101 T122 A123 T124 Y172 Y224 E248 G249 F297 F17 V76 T77 T78 T99 A100 T101 Y149 Y201 E225 G226 F274 Q8YEE8 DITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSAANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRDGQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNAQGTLFTNAKDATKNPAAKDAIQALKAKNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSAAVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKWDDGKIVGL 4n6y A 2.60 BS01 2HV A 1 L44 G45 F49 V52 A65 K67 E89 I104 L120 E121 R122 V126 L174 I185 D186 L13 G14 F18 V21 A34 K36 E58 I73 L89 E90 R91 V95 L143 I154 D155 2.7.11.1 P11309 EPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 4n6z A 2.20 BS01 2HW A 1 L44 F49 V52 A65 K67 I104 L120 E121 R122 D128 E171 L174 I185 D186 L12 F17 V20 A33 K35 I72 L88 E89 R90 D96 E139 L142 I153 D154 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 4n70 A 2.10 BS01 2HX A 1 L44 F49 A65 K67 I104 L120 E121 R122 P123 V126 D128 E171 L174 I185 D186 L13 F18 A34 K36 I73 L89 E90 R91 P92 V95 D97 E140 L143 I154 D155 2.7.11.1 P11309 EPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLHS 4n7a A 1.79 BS01 HEM A 1 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 V354 F380 L417 Q423 L433 I436 R440 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 V354 F380 L417 Q423 L433 I436 R440 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4n7a A 1.79 BS02 CA A 1 D110 T184 F186 D188 S190 D110 T184 F186 D188 S190 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4n7a A 1.79 BS03 3AX A 1 H109 R255 E258 H109 R255 E258 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4n7t A 2.00 BS01 MN A 1 D13 T92 D339 H340 H351 D12 T91 D338 H339 H350 5.4.2.7 Q8DTU0 STFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI 4n7t A 2.00 BS02 MN A 2 T92 D165 D298 H303 H351 T91 D164 D297 H302 H350 5.4.2.7 Q8DTU0 STFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI 4n7t A 2.00 BS03 AZI A 1 S270 V273 E316 F317 R320 S269 V272 E315 F316 R319 5.4.2.7 Q8DTU0 STFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI 4n7t B 2.00 BS01 MN B 1 D13 T92 D339 H340 H351 D11 T90 D337 H338 H349 5.4.2.7 Q8DTU0 TFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI 4n7t B 2.00 BS02 MN B 2 T92 D298 H303 H351 T90 D296 H301 H349 5.4.2.7 Q8DTU0 TFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI 4n7t B 2.00 BS03 AZI B 1 S270 V273 F317 R320 S268 V271 F315 R318 5.4.2.7 Q8DTU0 TFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI 4n8s A 2.30 BS01 XXH A 1 A14 Q15 N39 A40 Y261 G263 L264 A14 Q15 N39 A40 Y261 G263 L264 3.1.1.3 O59952 EVSQDLFNQFNLFAQYSAAAYCGKNNDAPAGTNITCTGNACPEVEKADATFLYSFEDSGVGDVTGFLALDNTNKLIVLSFRGSRSIENWIGNLNFDLKEINDICSGCRGHDGFTSSWRSVADTLRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLRGNGYDIDVFSYGAPRVGNRAFAEFLTVQTGGTLYRITHTNDIVPRLPPREFGYSHSSPEYWIKSGTLVPVTRNDIVKIEGIDATGGNNQPNIPDIPAHLWYFGLIGTCL 4n8s A 2.30 BS02 EAC A 1 R81 G82 S83 R84 S85 R81 G82 S83 R84 S85 3.1.1.3 O59952 EVSQDLFNQFNLFAQYSAAAYCGKNNDAPAGTNITCTGNACPEVEKADATFLYSFEDSGVGDVTGFLALDNTNKLIVLSFRGSRSIENWIGNLNFDLKEINDICSGCRGHDGFTSSWRSVADTLRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLRGNGYDIDVFSYGAPRVGNRAFAEFLTVQTGGTLYRITHTNDIVPRLPPREFGYSHSSPEYWIKSGTLVPVTRNDIVKIEGIDATGGNNQPNIPDIPAHLWYFGLIGTCL 4n8s B 2.30 BS01 XXH B 1 D5 N8 Q9 L12 E43 N73 D5 N8 Q9 L12 E43 N73 3.1.1.3 O59952 EVSQDLFNQFNLFAQYSAAAYCGKNNDAPAGTNITCTGNACPEVEKADATFLYSFEDSGVGDVTGFLALDNTNKLIVLSFRGSRSIENWIGNLNFDLKEINDICSGCRGHDGFTSSWRSVADTLRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLRGNGYDIDVFSYGAPRVGNRAFAEFLTVQTGGTLYRITHTNDIVPRLPPREFGYSHSSPEYWIKSGTLVPVTRNDIVKIEGIDATGGNNQPNIPDIPAHLWYFGLIGTCL 4n8s B 2.30 BS02 EAC B 1 S83 R84 S85 W89 S83 R84 S85 W89 3.1.1.3 O59952 EVSQDLFNQFNLFAQYSAAAYCGKNNDAPAGTNITCTGNACPEVEKADATFLYSFEDSGVGDVTGFLALDNTNKLIVLSFRGSRSIENWIGNLNFDLKEINDICSGCRGHDGFTSSWRSVADTLRQKVEDAVREHPDYRVVFTGHSLGGALATVAGADLRGNGYDIDVFSYGAPRVGNRAFAEFLTVQTGGTLYRITHTNDIVPRLPPREFGYSHSSPEYWIKSGTLVPVTRNDIVKIEGIDATGGNNQPNIPDIPAHLWYFGLIGTCL 4n94 A 1.73 BS01 2HO A 1 T172 G174 H175 L177 P242 V247 T166 G168 H169 L171 P236 V241 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n94 B 1.73 BS01 CA B 1 E6 G85 E87 E6 G85 E87 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n94 B 1.73 BS02 CA B 2 V179 S181 Q355 S356 V179 S181 Q355 S356 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n95 A 1.80 BS01 2HQ A 1 T172 G174 H175 R176 L177 V247 V360 T166 G168 H169 R170 L171 V241 V354 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n95 A 1.80 BS02 CA A 1 E95 T110 E89 T104 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n95 A 1.80 BS03 CA A 2 N32 P71 S109 T110 L111 N26 P65 S103 T104 L105 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n95 A 1.80 BS04 CA A 3 P213 R215 H226 P207 R209 H220 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n95 A 1.80 BS05 CA A 4 G85 E87 G79 E81 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n96 A 1.70 BS01 6NI A 1 T172 G174 V247 S346 V360 T162 G164 V237 S336 V350 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n96 A 1.70 BS02 CA A 1 G46 T47 E52 E202 G37 T38 E43 E192 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n96 A 1.70 BS03 CA A 2 E6 E8 G85 E6 E8 G76 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n96 B 1.70 BS01 CA B 1 E6 G85 E87 E6 G82 E84 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n97 A 1.97 BS01 2HU A 1 T172 G174 H175 V247 S346 V360 M362 T167 G169 H170 V242 S341 V355 M357 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n97 A 1.97 BS02 CA A 1 R103 R105 R98 R100 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n97 B 1.97 BS01 CA A 1 E303 I305 E302 I304 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMR 4n98 A 1.70 BS01 4FC A 1 R152 Y154 T172 G174 H175 R176 P242 V247 V360 M362 R146 Y148 T166 G168 H169 R170 P236 V241 V354 M356 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4n98 A 1.70 BS02 CA A 1 G46 T47 E202 G40 T41 E196 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4n98 A 1.70 BS03 CA A 2 S181 Q355 S356 S175 Q349 S350 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4n98 A 1.70 BS04 CA A 3 V5 E6 H9 V60 Q61 V5 E6 H9 V54 Q55 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4n98 B 1.70 BS01 CA B 1 G46 T47 M51 E202 G39 T40 M44 E195 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n98 B 1.70 BS02 CA B 2 V5 E6 H9 Q61 V5 E6 H9 Q54 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n98 B 1.70 BS03 CA B 3 V179 S181 S356 V172 S174 S349 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n99 A 2.30 BS01 2J1 A 1 R152 G174 H175 P242 V247 S346 M362 R146 G168 H169 P232 V237 S336 M352 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n99 A 2.30 BS02 CA A 1 V57 A58 V51 A52 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n99 A 2.30 BS03 CA A 2 R282 E316 L366 R272 E306 L356 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n99 A 2.30 BS04 CA A 3 G228 D229 F230 G218 D219 F220 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n99 B 2.30 BS01 CA B 1 E93 L98 S107 E92 L97 S106 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4n9a A 1.90 BS01 CA A 1 G280 V281 A294 N295 G272 V273 A286 N287 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4n9a A 1.90 BS02 2J2 A 1 T172 G174 H175 R176 L177 P242 V247 M362 T164 G166 H167 R168 L169 P234 V239 M354 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM 4n9a B 1.90 BS01 CA B 1 G46 T47 M51 E202 G40 T41 M45 E196 2.7.7.7 P0A988 MKFTVEREHLLKPLQQVSGPLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL 4naw A 2.19 BS01 III D 1 K54 K72 W73 A74 V75 E76 R79 L84 F87 K90 K2 K20 W21 A22 V23 E24 R27 L32 F35 K38 O94817 KKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG 4naw E 2.19 BS01 III H 1 K54 K72 W73 A74 V75 R79 L84 F87 K90 F91 K2 K20 W21 A22 V23 R27 L32 F35 K38 F39 O94817 KKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG 4naw I 2.19 BS01 III L 1 K54 K72 W73 A74 E76 R79 L84 F87 K90 F91 K2 K20 W21 A22 E24 R27 L32 F35 K38 F39 O94817 KKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG 4naw M 2.19 BS01 III P 1 K54 K72 W73 A74 E76 R79 L84 F87 K90 F91 K93 K2 K20 W21 A22 E24 R27 L32 F35 K38 F39 K41 O94817 KKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG 4nax A 1.30 BS01 GDS A 1 T28 P29 N30 F52 Q57 K70 I71 P72 E89 S90 M123 G127 P128 G131 W188 T26 P27 N28 F50 Q55 K68 I69 P70 E87 S88 M121 G125 P126 G129 W186 A5W1A6 ELSAFPITRKWPAKHPERLQLYSLPTPNGVKVSIMLEEIGLAYEAHKVSFDNDDQLSPEFISLSANNKIPAILDPNGPGGQPLPLFESGAILQYLAEKSGQLLSQDPAQRYQTLQWLMFQMGGIGPMFGQVGFFHFFAGKEYEDKRPRDRYVNESKRLLGVLDRHLKGRQWMAEEYSIADIAIFPWVRNLVERYNARDLVGFDQFKEVQRVLANFLERPAVQHGLKIPGAENLYFQG 4nax B 1.30 BS01 GDS B 1 T28 P29 N30 Q57 K70 I71 P72 E89 S90 M123 G127 P128 G131 W188 T27 P28 N29 Q56 K69 I70 P71 E88 S89 M122 G126 P127 G130 W187 A5W1A6 TELSAFPITRKWPAKHPERLQLYSLPTPNGVKVSIMLEEIGLAYEAHKVSFDNDDQLSPEFISLSANNKIPAILDPNGPGGQPLPLFESGAILQYLAEKSGQLLSQDPAQRYQTLQWLMFQMGGIGPMFGQVGFFHFFAGKEYEDKRPRDRYVNESKRLLGVLDRHLKGRQWMAEEYSIADIAIFPWVRNLVERYNARDLVGFDQFKEVQRVLANFLERPAVQHGLKIPG 4nc5 A 2.51 BS01 FSI A 1 R21 I22 R41 N86 Y179 Y181 L217 E218 R237 R304 Y334 R19 I20 R39 N78 Y163 Y165 L201 E202 R219 R280 Y310 3.2.1.18 Q9Y3R4 SLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRAAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYL 4ncz A 1.89 BS01 NHE A 1 R25 N26 I27 H122 V123 A124 F149 V158 R24 N25 I26 H121 V122 A123 F148 V157 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNR 4ncz A 1.89 BS02 CA A 1 E33 E75 E32 E74 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNR 4ncz B 1.89 BS01 NHE B 1 R25 N26 I27 Q86 H122 I151 V158 R24 N25 I26 Q85 H121 I150 V157 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLN 4ncz B 1.89 BS02 CA B 1 E33 E75 E32 E74 Q9KL03 NSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLN 4ncz C 1.89 BS01 CA A 1 E33 E75 E30 E72 Q9KL03 QLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 4ncz C 1.89 BS02 NHE C 1 R25 N26 A124 F149 R22 N23 A121 F146 Q9KL03 QLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVVEDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIYLHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE 4nea A 1.90 BS01 NAD A 1 I153 P155 W156 N157 K180 E183 A212 G213 G217 D218 T232 G233 G234 T237 H240 I241 E255 C289 E390 F392 I162 P164 W165 N166 K189 E192 A221 G222 G226 D227 T241 G242 G243 T246 H249 I250 E264 C298 E399 F401 1.2.1.8 Q5HCU0 MHHHHHHSAMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4nea B 1.90 BS01 NAD B 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 S214 G217 D218 F231 T232 G233 G234 T237 I241 E255 L256 C289 H336 E390 F392 I157 T158 P159 W160 N161 K184 S186 E187 G217 S218 G221 D222 F235 T236 G237 G238 T241 I245 E259 L260 C293 H340 E394 F396 1.2.1.8 Q5HCU0 QSNAMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4nea C 1.90 BS01 NAD C 1 I153 T154 P155 W156 N157 K180 P181 S182 E183 G213 G217 F231 T232 G233 G234 T237 I241 E255 L256 C289 H336 E390 F392 I154 T155 P156 W157 N158 K181 P182 S183 E184 G214 G218 F232 T233 G234 G235 T238 I242 E256 L257 C290 H337 E391 F393 1.2.1.8 Q5HCU0 AMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK 4nea D 1.90 BS01 NAD D 1 I153 T154 P155 W156 N157 K180 S182 E183 G213 G217 F231 T232 G233 G234 T237 H240 I241 E255 G257 C289 H336 E390 F392 I159 T160 P161 W162 N163 K186 S188 E189 G219 G223 F237 T238 G239 G240 T243 H246 I247 E261 G263 C295 H342 E396 F398 1.2.1.8 Q5HCU0 YFQSNAMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK