2m7y A BS01 ZN A 1 C14 H16 C23 C26 C14 H16 C23 C26 P12296 GSTAMATTMEQEICAHSMTFEECPKCSALQYRNGFYLLKYDEEWYPEELLTDGEDDVFDPDLDMEVVFETQ 2yn8 A 2.11 BS01 STU A 1 I621 G622 A623 V629 A645 K647 E664 T693 E694 F695 M696 G699 A700 R744 L747 S757 D758 I14 G15 A16 V22 A33 K35 E52 T81 E82 F83 M84 G87 A88 R132 L135 S145 D146 2.7.10.1 P54760 23840071 KEIDVSYVKIEEVIGAGEFGEVCRGRLKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQIVSALDKMIRNPASLKIVA 2ynb B 1.96 BS01 G85 B 1 M25 T26 H41 L49 Y54 F143 G146 S147 C148 H166 Q167 M168 E169 L170 H175 D190 K191 Q192 T193 Q195 M25 T26 H41 L49 Y54 F143 G146 S147 C148 H166 Q167 M168 E169 L170 H175 D190 K191 Q192 T193 Q195 3.4.22.69 P0C6T4 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDMLAHRTGVSVEQMLAAIQSLHAGFQGKTILGQSTLEDEFTPDDVNMQVMG 2yor A 2.19 BS01 HEM A 1 P35 C36 P37 G38 L39 I59 L67 F69 A77 T78 A81 L115 F121 E122 G123 S126 M127 T128 R189 E196 F199 P200 L203 P31 C32 P33 G34 L35 I55 L63 F65 A73 T74 A77 L111 F117 E118 G119 S122 M123 T124 R185 E192 F195 P196 L199 1.11.2.1 B9W4V6 24126915 PPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPVQIINAVQEGLNFDNQAAVFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVIQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFFFQGVAAGCTQVFPYGRD 2yor A 2.19 BS02 MG A 1 E122 G123 S126 E118 G119 S122 1.11.2.1 B9W4V6 24126915 PPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPVQIINAVQEGLNFDNQAAVFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVIQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFFFQGVAAGCTQVFPYGRD 2yor A 2.19 BS03 MZ0 A 1 A77 F121 T192 E196 F199 A73 F117 T188 E192 F195 1.11.2.1 B9W4V6 24126915 PPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPVQIINAVQEGLNFDNQAAVFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVIQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFFFQGVAAGCTQVFPYGRD 2yor B 2.19 BS03 MZ0 B 1 F69 A77 F121 T192 E196 F199 F66 A74 F118 T189 E193 F196 1.11.2.1 B9W4V6 24126915 LPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPVQIINAVQEGLNFDNQAAVFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVIQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFFFQGVAAGCTQVFPYGR 2yp1 D 2.31 BS01 HEM D 1 P35 C36 P37 G38 L39 V63 L67 F69 A77 T78 A81 F121 E122 G123 S126 M127 T128 R189 E196 F199 L203 F204 P32 C33 P34 G35 L36 V60 L64 F66 A74 T75 A78 F118 E119 G120 S123 M124 T125 R186 E193 F196 L200 F201 1.11.2.1 B9W4V6 24126915 LPPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVATPVQIINAVQEGLNFDNQAAVFATYAAHLVDGNLITDLLSIGRKTRLTGPDPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNRFGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLFVDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVIQAHPMQPGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKALNTNLDFFFQGVAAGCTQVFPYG 3j43 3 9.00 BS01 NUC 2 1 R27 K31 R33 K34 G35 T36 N37 E38 K41 V57 D58 P59 I62 K83 I92 E93 V94 A95 A97 R27 K31 R33 K34 G35 T36 N37 E38 K41 V57 D58 P59 I62 K83 I92 E93 V94 A95 A97 MAKPSYVKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVIIAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVAAASVAIIEPGKARDLVEEIAMKVKELMK 3j43 A 9.00 BS01 NUC 2 1 T9 R10 K16 D38 N45 R46 V47 K83 R93 V96 R97 R98 K99 T100 T101 R102 R118 M120 M126 R127 R128 I129 Q130 T131 S132 R135 R138 K139 K176 I177 Y178 P179 K187 T1 R2 K8 D30 N37 R38 V39 K75 R85 V88 R89 R90 K91 T92 T93 R94 R110 M112 M118 R119 R120 I121 Q122 T123 S124 R127 R130 K131 K168 I169 Y170 P171 K179 TRDKWKLKQWYIIYAPDFFGGVEVGLTPADDPEKVLNRVVEVTLKDVTGDFTKSHVKLYFQVYDVKGQNAYTKFKGMKLARSYIRSLVRRKTTRIDGIFNITTKDGYKLRVMAMAIAMRRIQTSQERAIRKIMQEIIYKKAEELNFKDFVLESVNGKIAAEIAKEAKKIYPLRKAEIRKIKVLEEPQVIA 3j43 B 9.00 BS01 NUC 2 1 Q23 K24 K29 V35 R36 Q37 Y41 G94 R95 L97 P98 T102 N103 P104 A105 V106 Q125 R128 R201 R202 Q23 K24 K29 V35 R36 Q37 Y41 G94 R95 L97 P98 T102 N103 P104 A105 V106 Q125 R128 R201 R202 MADEYLVPLDQYLAAGVHIGTQQKTKDMKKFIYRVRQDGLYVLDVRKTDERLKVAGKFLAKFEPQSILAVSVRLYGQKPVKKFGEVTGARAIPGRFLPGTMTNPAVKNFFEPDVLIVTDPRADHQAMREAVEIGIPIVALVDTENLLSYVDLAIPTNNKGRKALALIYWILAREILYNRGEIQSREDFKIPVEEFEMKIVRR 3j43 C 9.00 BS01 NUC 2 1 M1 A2 I3 R131 S133 G134 K135 E139 R140 A141 K142 S143 R145 Y147 A152 K153 V154 G155 N156 P157 Y166 Q168 L170 L171 K172 L173 G174 V175 K179 M1 A2 I3 R131 S133 G134 K135 E139 R140 A141 K142 S143 R145 Y147 A152 K153 V154 G155 N156 P157 Y166 Q168 L170 L171 K172 L173 G174 V175 K179 MAIERYFIREAVREMLIDEFLEKELRRAGYGGLDIKKTPLGTKVIIFAANPGYVIGRGGRRIRELTRILEKQFGLENPQIEVEEIKNPYLNAKVQAVRLAQALERGIHFRRAAYAALRAIMNNGARGVEIRLSGKLTGERAKSIRFYQGYLAKVGNPAETLVSKGYAQALLKLGVIGVKVAIMPPG 3j43 D 9.00 BS01 NUC 2 1 K9 K10 Y11 T13 P15 H16 P17 W18 K20 L23 R27 V28 M30 D31 K36 N37 K38 K39 W42 K43 K49 R52 R53 R54 R56 E69 Q72 R76 R79 R116 T117 R119 Q120 R122 V126 H127 Q135 I136 R138 S139 P140 Y142 R156 S158 H165 P166 E167 M170 K173 K1 K2 Y3 T5 P7 H8 P9 W10 K12 L15 R19 V20 M22 D23 K28 N29 K30 K31 W34 K35 K41 R44 R45 R46 R48 E61 Q64 R68 R71 R108 T109 R111 Q112 R114 V118 H119 Q127 I128 R130 S131 P132 Y134 R148 S150 H157 P158 E159 M162 K165 KKYETPPHPWIKERLDRERVLMDKYELKNKKELWKHETQLKNFRRRARRLLAARGKQAEIEREQLLARLKRLGLLPEDAVLDDVLSLTIEDILERRLQTIVYKKGLARTMRQARQLIVHGHIEVNGQIIRSPSYLVLKEEEDTITYARTSPFANPQHPERMMIEKAKQGGEA 3j43 E 9.00 BS01 NUC 2 1 R3 K4 G5 P6 K7 R8 H9 K11 L13 A15 Y20 I21 E22 R23 K24 Y26 K27 W28 A29 V30 R31 R33 P34 G35 P36 N38 M39 R40 L46 R50 T58 A59 R60 R63 K64 N67 R76 R78 K79 Y81 K82 I107 K109 R128 N129 K130 R131 M132 I133 K134 G135 A136 V138 Q139 N141 G145 T146 N147 I149 A153 E154 K155 F159 R171 G190 K191 N192 F205 P206 M207 G208 W209 D224 Y229 R1 K2 G3 P4 K5 R6 H7 K9 L11 A13 Y18 I19 E20 R21 K22 Y24 K25 W26 A27 V28 R29 R31 P32 G33 P34 N36 M37 R38 L44 R48 T56 A57 R58 R61 K62 N65 R74 R76 K77 Y79 K80 I105 K107 R126 N127 K128 R129 M130 I131 K132 G133 A134 V136 Q137 N139 G143 T144 N145 I147 A151 E152 K153 F157 R169 G188 K189 N190 F203 P204 M205 G206 W207 D222 Y227 RKGPKRHLKRLAAPTSWYIERKAYKWAVRPRPGPHNMRTSIPLLYIVRDYLGYAKTAREARKILNEGKFLVDGRVRKDYKFPVGIMDVVSIPETGEHYRVLPNRIGKLILHPISEDEAFIKPLRIRNKRMIKGARVQLNFHDGTNHIVSIAEKDNYFTSYTVLMKVPEREILEVLPFEKGAYVFVTQGKNVARKGRIVEIKRFPMGWPDVVTIEDEEGELFDTLKEYAFVVGTDKPKISLP 3j43 F 9.00 BS01 NUC 2 1 T71 V72 R73 M74 T75 D76 S77 R79 R80 R84 I100 H102 K104 I108 K112 L119 K148 E149 G150 S151 V152 L163 V166 I167 W184 S185 Q186 T187 F188 E190 T191 R192 T193 N196 F197 K199 T71 V72 R73 M74 T75 D76 S77 R79 R80 R84 I100 H102 K104 I108 K112 L119 K148 E149 G150 S151 V152 L163 V166 I167 W184 S185 Q186 T187 F188 E190 T191 R192 T193 N196 F197 K199 MSQEWKEYAKRVLDEWEPKTKLGMMVKEGQITDIHEIFRRGYQIKEPEIIDVLLPEVNARENQEVLDIALTVRMTDSGRRVRFRVLAAVGNRDGYVGLGIGHGKEVGIAIRKAINYAKLNIIEIKRGCGSWECRCRRPHSVPFAVEGKEGSVRVRLIPGPRGLGLVIGDVGKKILRLAGVQDVWSQTFGETRTTVNFAKAVFNALYNTNRVAISPEM 3j43 G 9.00 BS01 NUC 2 1 K5 G14 A16 K17 Q18 R64 T67 K69 D70 G71 P73 R75 P76 D77 I78 H79 R83 R85 V86 L87 P92 G93 F94 K97 E98 K99 G100 E101 R102 R103 K104 K105 T106 Q118 N120 K5 G14 A16 K17 Q18 R64 T67 K69 D70 G71 P73 R75 P76 D77 I78 H79 R83 R85 V86 L87 P92 G93 F94 K97 E98 K99 G100 E101 R102 R103 K104 K105 T106 Q118 N120 MATFKLVISDPKSGIAKQVEITGAETEKLIGKRIGDQIPAKELNINLNELFGKEFPEDVKLEIRGGTDKDGFPMRPDIHGPRRVRVLLSKGPGFRPKEKGERRKKTVRGNTISPEIVQVNVKLVY 3j43 H 9.00 BS01 NUC 2 1 M1 R8 H46 T47 H48 R50 H55 K58 E65 R66 N69 R73 S74 G75 G76 S77 H78 Y79 K80 V81 A82 G83 H84 F85 M86 R87 R88 E89 H90 R91 L93 N94 K96 K97 V98 K99 E102 M155 R156 D159 R163 C173 Y174 R175 N176 K177 M178 S179 F180 M1 R8 H46 T47 H48 R50 H55 K58 E65 R66 N69 R73 S74 G75 G76 S77 H78 Y79 K80 V81 A82 G83 H84 F85 M86 R87 R88 E89 H90 R91 L93 N94 K96 K97 V98 K99 E102 M155 R156 D159 R163 C173 Y174 R175 N176 K177 M178 S179 F180 MAKPLNERFFIPHEIKVMGRWSTEDVEVRDPSLKPYINLEPRLLPHTHGRHAKKHFGKANVHIVERLINKIMRSGGSHYKVAGHFMRREHRSLNSKKVKAYEVVKEAFKIIEQRTGKNPIQVLVWAIENAAPREDTTSVMFGGIRYHVAVDISPMRRLDVALRNIALGASAKCYRNKMSFAEALAEEIILAANKDPKSYAYSKKLEIERIAESSR 3j43 I 9.00 BS01 NUC 2 1 T2 L4 D5 N9 S12 H13 N16 R19 K22 K28 A30 S31 K32 L33 R57 K71 K76 P80 K82 V83 R92 F93 S105 T106 S107 G109 G122 G123 R124 T1 L3 D4 N8 S11 H12 N15 R18 K21 K27 A29 S30 K31 L32 R56 K70 K75 P79 K81 V82 R91 F92 S104 T105 S106 G108 G121 G122 R123 TLLDPLANALSHITNSERVGKREVYIKPASKLIGEVLRVMQKYGYIGEFEFIDDGRAGVYRVQLLGRINKAGAIKPRFPVKVSEFEKWEKRFLPAFEFGILIVSTSQGVMSHKEAIEKGIGGRLIAYVY 3j43 J 9.00 BS01 NUC 2 1 M1 I3 W4 Q5 G6 R7 L9 K10 K11 P12 S13 G14 G15 R16 I17 L19 A20 R21 K22 K23 R24 K25 R26 E27 R30 E31 P32 S33 R36 K42 R43 K44 I45 R47 T48 Y49 G50 N52 R53 R56 T58 Y62 N64 F66 S69 G70 K71 G72 R73 K74 A85 T96 K97 G98 T111 S112 R113 G115 Q116 D117 V119 N121 I123 M1 I3 W4 Q5 G6 R7 L9 K10 K11 P12 S13 G14 G15 R16 I17 L19 A20 R21 K22 K23 R24 K25 R26 E27 R30 E31 P32 S33 R36 K42 R43 K44 I45 R47 T48 Y49 G50 N52 R53 R56 T58 Y62 N64 F66 S69 G70 K71 G72 R73 K74 A85 T96 K97 G98 T111 S112 R113 G115 Q116 D117 V119 N121 I123 MAIWQGRSLKKPSGGRIVLARKKRKRELGREPSNTRVAEQDKRKIIRTYGGNRKVRLTAAAYANVFDKSGKGRKVRIIRVIENPANRQFARRNIITKGAIIETEIGKAKVTSRPGQDGVVNAILLEE 3j43 K 9.00 BS01 NUC 2 1 M1 I3 Q5 T7 R10 K11 I14 R16 V18 R20 K23 R25 R27 K31 I35 E37 P38 E39 I40 D61 K65 G68 G69 G70 F71 M72 G73 Q74 V108 D110 P111 R112 R113 T114 E115 P116 H117 K118 P119 R121 S122 T123 K124 P126 R127 K129 R130 Q131 K132 S133 Y134 R135 M1 I3 Q5 T7 R10 K11 I14 R16 V18 R20 K23 R25 R27 K31 I35 E37 P38 E39 I40 D61 K65 G68 G69 G70 F71 M72 G73 Q74 V108 D110 P111 R112 R113 T114 E115 P116 H117 K118 P119 R121 S122 T123 K124 P126 R127 K129 R130 Q131 K132 S133 Y134 R135 MRIIQTTGKRKTAIARAVIREGKGRVRINGKPVEIIEPEIARFTILEPLILAGEEIWNSVDIDVKVEGGGFMGQAEAARMAIARALVEWTGDMSLKEKFMKYDRTMLVGDPRRTEPHKPNRSTKGPRAKRQKSYR 3j43 L 9.00 BS01 NUC 2 1 K3 R5 K7 V13 R14 L16 D17 S35 G36 P37 I38 P39 L40 P41 T42 K43 R44 I45 R46 T48 R50 K51 S52 P53 D54 G55 E56 G57 S58 F61 R63 R67 H69 R71 E97 K3 R5 K7 V13 R14 L16 D17 S35 G36 P37 I38 P39 L40 P41 T42 K43 R44 I45 R46 T48 R50 K51 S52 P53 D54 G55 E56 G57 S58 F61 R63 R67 H69 R71 E97 MQKARIKIASTNVRSLDEVANQIKQIAERTGVRMSGPIPLPTKRIRITTRKSPDGEGSATFDRWELRVHKRLIDIEADERAMRQIMRIRVPEDVTIEIELIS 3j43 M 9.00 BS01 NUC 2 1 H18 Y20 N24 N25 I27 H29 T31 G35 A36 E37 T38 R41 S43 G45 M46 K49 D51 R52 E54 R82 R84 G87 S89 K90 I121 P122 H123 D124 R127 K129 G130 G131 R132 R133 G134 R135 R136 V137 H14 Y16 N20 N21 I23 H25 T27 G31 A32 E33 T34 R37 S39 G41 M42 K45 D47 R48 E50 R78 R80 G83 S85 K86 I117 P118 H119 D120 R123 K125 G126 G127 R128 R129 G130 R131 R132 V133 QVNIKKKEKWGIAHIYSSFNNTIIHITDITGAETISRWSGGMVVKADRDEPSPYAAMLAARRAAEEALEKGIVGVHIRVRAPGGSKSKTPGPGAQAAIRALARAGLKIGRVEDVTPIPHDGTRPKGGRRGRRV 3j43 N 9.00 BS01 NUC 2 1 G3 K4 K5 A6 P7 N8 G9 E10 F11 R14 K15 K19 R20 K21 F23 R24 W25 S26 D27 R29 Y30 K31 R33 R36 L37 K38 G46 P48 Q49 A50 R51 K63 Q64 N66 S67 R70 K71 R74 I78 K79 P89 G90 D91 G92 A93 E106 G107 I108 G110 P111 K112 G113 G114 S115 M116 D118 P120 G121 R123 K128 R131 S133 K135 E136 V138 K139 G140 R141 K142 G1 K2 K3 A4 P5 N6 G7 E8 F9 R12 K13 K17 R18 K19 F21 R22 W23 S24 D25 R27 Y28 K29 R31 R34 L35 K36 G44 P46 Q47 A48 R49 K61 Q62 N64 S65 R68 K69 R72 I76 K77 P87 G88 D89 G90 A91 E104 G105 I106 G108 P109 K110 G111 G112 S113 M114 D116 P118 G119 R121 K126 R129 S131 K133 E134 V136 K137 G138 R139 K140 GKKAPNGEFAGRKLKLKRKKFRWSDIRYKRRVLRLKEKSDPLEGAPQARGIVLEKIAVEAKQPNSGMRKAVRVQLIKNGKVVTAFCPGDGAIKFIDEHDEVIIEGIGGPKGGSMGDIPGIRYKVVKVNRVSLKELVKGRKEKPRR 3j43 O 9.00 BS01 NUC 2 1 K19 Q20 W23 T26 K29 G30 I31 G32 I33 N34 F35 F48 K50 W77 A78 N80 R81 P82 K83 E86 L98 I102 D105 R108 Y115 R116 R119 H120 L124 P125 V126 R127 G128 Q129 R130 T131 R132 S133 N134 F135 R136 R137 Q139 T140 G142 V143 S144 R145 K146 K148 K19 Q20 W23 T26 K29 G30 I31 G32 I33 N34 F35 F48 K50 W77 A78 N80 R81 P82 K83 E86 L98 I102 D105 R108 Y115 R116 R119 H120 L124 P125 V126 R127 G128 Q129 R130 T131 R132 S133 N134 F135 R136 R137 Q139 T140 G142 V143 S144 R145 K146 K148 MANFRHIVRVAGVDLDGNKQLRWALTAIKGIGINFATMVCRVAGLDPFMKAGYLTDEQVKKIEEILADPVAHGIPRWAVNRPKDYETGRDLHLITAKLDMAIREDIMRLRRIRAYRGIRHELGLPVRGQRTRSNFRRGQTVGVSRKKK 3j43 P 9.00 BS01 NUC 2 1 M1 A2 K3 A4 D5 Y6 N7 K8 R9 K10 P11 R12 K13 F14 G15 K16 G17 R19 C24 Q26 Y27 G28 P29 I30 I31 R32 I33 Q34 R40 H41 R44 K54 Y55 E56 M1 A2 K3 A4 D5 Y6 N7 K8 R9 K10 P11 R12 K13 F14 G15 K16 G17 R19 C24 Q26 Y27 G28 P29 I30 I31 R32 I33 Q34 R40 H41 R44 K54 Y55 E56 MAKADYNKRKPRKFGKGARRCIRCGQYGPIIRIQGLMLCRHCFREVAPKLGFRKYE 3j43 Q 9.00 BS01 NUC 2 1 M1 A2 R3 M4 H5 A6 R7 K8 R9 G10 K11 S12 G13 S14 K15 R16 P17 A48 M49 G51 T52 R55 P61 S62 V63 K64 R74 N75 T77 I78 T79 D94 L98 R101 L105 H108 H112 P113 K114 D115 L116 H117 R120 Q123 L124 S127 K128 R131 L132 K134 Y135 Y136 K139 K141 M1 A2 R3 M4 H5 A6 R7 K8 R9 G10 K11 S12 G13 S14 K15 R16 P17 A48 M49 G51 T52 R55 P61 S62 V63 K64 R74 N75 T77 I78 T79 D94 L98 R101 L105 H108 H112 P113 K114 D115 L116 H117 R120 Q123 L124 S127 K128 R131 L132 K134 Y135 Y136 K139 K141 MARMHARKRGKSGSKRPPRTAPPIWVEYTVEEIENLVVKLRKEGYSTAMIGTILRDQYGIPSVKLFKDPDNPNRNLTITRILEKHGLAPEIPEDLMFLIRRAVNLRKHLEQHPKDLHSMRGLQLIESKIRRLVKYYKRKGKLPKNWRYDPETAKLLVR 3j43 R 9.00 BS01 NUC 2 1 R3 D4 I5 G6 D18 K20 P22 W23 N26 K28 I29 H30 G31 R32 F34 S40 P43 R44 K45 T46 R51 Y53 F55 N58 K59 Y60 E61 L65 R66 R67 K69 H71 E90 R92 P93 L94 S95 K96 T97 K98 H99 F100 E110 E111 R112 R113 R3 D4 I5 G6 D18 K20 P22 W23 N26 K28 I29 H30 G31 R32 F34 S40 P43 R44 K45 T46 R51 Y53 F55 N58 K59 Y60 E61 L65 R66 R67 K69 H71 E90 R92 P93 L94 S95 K96 T97 K98 H99 F100 E110 E111 R112 R113 MMRDIGLRVQPPAEKCDDPKCPWHGNLKIHGRVFEGIVVSDKPRKTVTVERQYYFYLNKYERYELRRSKIHAHNPPCINAKVGDKVLIAETRPLSKTKHFVVVAVLERAEERR 3j43 S 9.00 BS01 NUC 2 1 M1 G2 K3 I4 R5 Q6 G7 F8 K10 T26 F28 K32 T42 S43 K44 K45 I46 N48 R49 G52 Y53 T55 K56 R59 M60 E63 G64 K65 L67 M1 G2 K3 I4 R5 Q6 G7 F8 K10 T26 F28 K32 T42 S43 K44 K45 I46 N48 R49 G52 Y53 T55 K56 R59 M60 E63 G64 K65 L67 MGKIRQGFIKRVARELVNKYPNEFTTDFEHNKKKVQELTNVTSKKIRNRIAGYVTKLVRMKMEGKIL 3j43 T 9.00 BS01 NUC 2 1 R26 L27 F28 P29 A30 R31 R33 R34 S35 R38 G39 L40 T41 E43 Q44 K46 L47 R49 K50 K58 Y59 K60 K61 R64 T65 H66 R68 D69 H84 N85 G86 K87 F89 Y102 G104 T109 R110 K111 E114 H115 G116 R21 L22 F23 P24 A25 R26 R28 R29 S30 R33 G34 L35 T36 E38 Q39 K41 L42 R44 K45 K53 Y54 K55 K56 R59 T60 H61 R63 D64 H79 N80 G81 K82 F84 Y97 G99 T104 R105 K106 E109 H110 G111 FRYRGYTLEQLMNMSLEELARLFPARQRRSLKRGLTPEQKKLLRKIRLAKKGKYKKPIRTHCRDMIILPEMVGLTIYVHNGKEFVPVEIKPEMIGHYLGEFAPTRKKVEHG 3j43 U 9.00 BS01 NUC 2 1 M1 A2 T3 Y5 D6 D10 V13 V35 K36 T37 R39 K41 E42 R43 W50 Y53 R54 S57 R60 R61 Y63 G69 I70 E71 R72 R74 T75 Y76 Y77 R80 K81 N82 R83 G84 H85 A86 P87 F90 Y91 K92 A93 G94 G95 R99 K100 Q103 K117 G118 R119 R126 S127 D130 A133 T134 K137 M1 A2 T3 Y5 D6 D10 V13 V35 K36 T37 R39 K41 E42 R43 W50 Y53 R54 S57 R60 R61 Y63 G69 I70 E71 R72 R74 T75 Y76 Y77 R80 K81 N82 R83 G84 H85 A86 P87 F90 Y91 K92 A93 G94 G95 R99 K100 Q103 K117 G118 R119 R126 S127 D130 A133 T134 K137 MATVYDVPGDLLVERVAQRLKEIPEIKPPEWAPFVKTGRHKERLPEQEDWWYYRVASILRRVYLDGPVGIERLRTYYGGRKNRGHAPEKFYKAGGSIIRKALQQLEAAGFVEKVPGKGRVITPKGRSFLDKIATELKKELEEII 3j43 V 9.00 BS01 NUC 2 1 G27 E28 P29 T30 P31 S32 R33 Y55 I56 R57 Y59 F60 G61 Y80 E84 Y85 I88 R89 E94 K95 K96 E97 G98 E99 G27 E28 P29 T30 P31 S32 R33 Y55 I56 R57 Y59 F60 G61 Y80 E84 Y85 I88 R89 E94 K95 K96 E97 G98 E99 MEIRIKEIKENKLIGRKEIYFEIYHPGEPTPSRKDVKGKLVAMLDLNPETTVIQYIRSYFGSYISKGYAKAYDSKERMLYIEPEYILIRDGLIEKKEGE 3j43 W 9.00 BS01 NUC 2 1 M1 P9 R10 F28 H30 A32 T48 G49 G50 K51 M1 P9 R10 F28 H30 A32 T48 G49 G50 K51 MAKPIIPMPRSRFLRVKCIDCGNEQIVFSHPATKVRCLICGATLVEPTGGKGIVKAKILEVLE 3j43 X 9.00 BS01 NUC 2 1 R17 T20 T21 G22 D23 T25 P48 R71 R17 T20 T21 G22 D23 T25 P48 R71 MAEDEGYPAEVIEIIGRTGTTGDVTQVKVRILEGRDKGRVIRRNVRGPVRIGDILILRETEREAREIKSRR 3j43 Y 9.00 BS01 NUC 2 1 M1 G2 Q3 K4 W5 K6 L7 Y8 K18 N19 G28 V29 F30 A32 D33 H34 R37 W38 A39 G41 K42 C43 G44 T46 E47 M1 G2 Q3 K4 W5 K6 L7 Y8 K18 N19 G28 V29 F30 A32 D33 H34 R37 W38 A39 G41 K42 C43 G44 T46 E47 MGQKWKLYEIKDGKVIRKNKFCPRCGPGVFMADHGDRWACGKCGYTEWKK 3j44 5 9.00 BS01 NUC 1 1 A14 G15 R16 R17 N31 K42 K44 R46 R47 M48 N49 K51 A12 G13 R14 R15 N29 K40 K42 R44 R45 M46 N47 K49 AIDVGRIAVVIAGRRAGQKVVVVDIIDKNFVLVTGAGLNKVKRRRMNIKHIEPLPQKIDIPRGASDEEVRAALEKAGISLA 3j44 A 9.00 BS01 NUC 1 1 M1 R5 Q6 K7 R22 N23 F24 S27 E29 N33 R56 K58 P94 R95 Q96 A97 R98 K99 K102 K103 R123 Y124 G126 R128 N129 K130 R154 Q156 K158 P161 V162 H164 P166 G168 E196 K205 T206 T207 M1 R5 Q6 K7 R22 N23 F24 S27 E29 N33 R56 K58 P94 R95 Q96 A97 R98 K99 K102 K103 R123 Y124 G126 R128 N129 K130 R154 Q156 K158 P161 V162 H164 P166 G168 E196 K205 T206 T207 MPFDRQKIVKAVKEAKARAKPRNFTQSVEVAVNLKDIDLKRPENRFKLEVVLPHGRGKDVKIAVIADGAVAEAARKLGLDVISSAELEEIASSPRQARKLAKKYDFFIAEAPLMPKIGRYLGRYLGPRNKMPVVVPPTLTDLTPIVEKLKKTVRIQLKNNPVVHAPVGTEKMSDEEIAENIEAVLNAIIGKLERGESQVKSVYVKTTMGPAVKIEG 3j44 a 9.00 BS01 NUC 1 1 K4 A5 F11 T12 P14 K16 K19 K20 I21 V22 P23 R24 W25 K26 R30 V32 K33 F34 R36 F38 R41 H42 K44 I49 I50 D51 N55 E56 W59 E60 R61 E64 K65 K69 K1 A2 F8 T9 P11 K13 K16 K17 I18 V19 P20 R21 W22 K23 R27 V29 K30 F31 R33 F35 R38 H39 K41 I46 I47 D48 N52 E53 W56 E57 R58 E61 K62 K66 KAGEEVIFTVPIKKIKKIVPRWKRAPRAVKFVREFVARHAKAQEVIIDPKVNEKIWERGIEKPPSKLRVKVKVETVRIAYVT 3j44 B 9.00 BS01 NUC 1 1 M1 G2 K3 S4 I6 Q7 Q8 R9 R10 G11 K12 S14 P15 T16 K18 S19 S21 H22 R23 F24 R25 G26 A27 P32 Y35 H50 P52 R54 T55 I114 P115 G116 K120 Y121 V122 R123 A124 G125 G126 T127 L143 P144 S145 K149 M154 G165 G166 R167 L168 E169 K170 L172 V173 K174 A175 G176 Y179 Y180 K181 R185 N186 K187 F188 W189 P190 P192 R193 G194 V195 K196 M197 N198 A199 V200 N201 G205 G206 K207 E208 H209 H210 G212 K213 P214 T215 T216 S218 R219 R220 P222 P223 G224 R225 K226 V227 G228 H229 I230 A231 A232 R233 R234 T235 R237 R238 K239 M1 G2 K3 S4 I6 Q7 Q8 R9 R10 G11 K12 S14 P15 T16 K18 S19 S21 H22 R23 F24 R25 G26 A27 P32 Y35 H50 P52 R54 T55 I114 P115 G116 K120 Y121 V122 R123 A124 G125 G126 T127 L143 P144 S145 K149 M154 G165 G166 R167 L168 E169 K170 L172 V173 K174 A175 G176 Y179 Y180 K181 R185 N186 K187 F188 W189 P190 P192 R193 G194 V195 K196 M197 N198 A199 V200 N201 G205 G206 K207 E208 H209 H210 G212 K213 P214 T215 T216 S218 R219 R220 P222 P223 G224 R225 K226 V227 G228 H229 I230 A231 A232 R233 R234 T235 R237 R238 K239 MGKSLIQQRRGKGSPTFKSPSHRFRGAVKYIPLNYTQEKTLRGVVEEIMHDPGRTAPVARVKFENGIEKLIIAPEGLLVGQEIYIGPDAPIAVGNTLPLAKIPEGTYVYNIEGIPGDGGKYVRAGGTYALVVSREPDKVIVQLPSGELKAFNPMCRATIGVVAGGGRLEKPLVKAGKAYYKYKARNKFWPTPRGVKMNAVNHPFGGKEHHPGKPTTTSRRAPPGRKVGHIAARRTGRRK 3j44 b 9.00 BS01 NUC 1 1 E3 F6 K7 L9 L10 R13 R15 L16 K17 R18 K19 K20 F23 R25 Q26 E27 W29 R30 Y31 P32 K33 F34 K35 K39 W40 R41 R42 K44 G45 I46 D47 K49 R51 L52 K53 K55 G56 R59 S62 I63 G64 W65 S66 S67 K69 V71 R72 G73 L74 H75 S77 L83 H85 N86 K88 E89 R101 I102 H104 T105 V106 G107 K108 K109 K110 R111 K124 L126 E1 F4 K5 L7 L8 R11 R13 L14 K15 R16 K17 K18 F21 R23 Q24 E25 W27 R28 Y29 P30 K31 F32 K33 K37 W38 R39 R40 K42 G43 I44 D45 K47 R49 L50 K51 K53 G54 R57 S60 I61 G62 W63 S64 S65 K67 V69 R70 G71 L72 H73 S75 L81 H83 N84 K86 E87 R99 I100 H102 T103 V104 G105 K106 K107 K108 R109 K122 L124 EKEFKRLLRVRARLKRKKPRFLRQEWWRYPKFKNDPKWRRPKGIDSKMRLKLKGKPRSPSIGWSSPKLVRGLHPSGYEEVLVHNVKELEALDPKRQAARIAHTVGKKKRIEIIKRAEELGIKVLNPR 3j44 C 9.00 BS01 NUC 1 1 M1 G2 K3 V4 H5 R6 P7 R8 R9 G10 S11 L12 G13 F14 P16 R17 K18 R19 K21 R26 R28 S29 M48 T49 H50 P58 G59 M68 P69 R84 Y86 R87 L91 L93 E94 T95 A96 T97 I100 K126 R130 I132 A133 T134 P136 K137 Q146 R164 K175 L176 K177 K178 K179 E181 M183 E184 K226 G227 G229 T230 Q231 G232 V234 K235 R236 I239 K240 L241 R242 H244 K245 S247 K248 R250 R251 K252 V253 G254 S255 I256 G257 P258 W259 H260 P261 A262 R263 V264 M265 W266 T267 V268 P269 M270 A271 G272 Q273 H277 H278 R279 T280 E281 L282 N283 K284 K308 G309 F311 H313 Y314 I316 S327 A331 K333 R334 R339 I342 R343 K346 K347 K348 E362 S363 K364 Q365 M1 G2 K3 V4 H5 R6 P7 R8 R9 G10 S11 L12 G13 F14 P16 R17 K18 R19 K21 R26 R28 S29 M48 T49 H50 P58 G59 M68 P69 R84 Y86 R87 L91 L93 E94 T95 A96 T97 I100 K103 R107 I109 A110 T111 P113 K114 Q123 R141 K152 L153 K154 K155 K156 E158 M160 E161 K203 G204 G206 T207 Q208 G209 V211 K212 R213 I216 K217 L218 R219 H221 K222 S224 K225 R227 R228 K229 V230 G231 S232 I233 G234 P235 W236 H237 P238 A239 R240 V241 M242 W243 T244 V245 P246 M247 A248 G249 Q250 H254 H255 R256 T257 E258 L259 N260 K261 K285 G286 F288 H290 Y291 I293 S304 A308 K310 R311 R316 I319 R320 K323 K324 K325 E339 S340 K341 Q342 MGKVHRPRRGSLGFSPRKRAKSIVPRIRSWPKETEVRMLGFAGYKAGMTHILMIDDEPGLTNGKEIFMPVTIIETPPLRVFGIRAYRMGYLGLETATEVIVPKLLERRIATLPKNYTQEMFEQKLGQLEDMIKEGEIVDVRAIVATQPWVIKLKKKPEVMEYAIGGTSVEEKFNYIKEKLGKELRVGEVLKEGELLDVIAVTKGKGTQGPVKRWGIKLRAHKDSKGRRKVGSIGPWHPARVMWTVPMAGQMGFHHRTELNKRLIAIGENGKLKLDENTEIEITPKGGFPHYGIVRSDFMMIAGSVPGAIKRIIRVRPAIRPPKKKPPVQRPQITYVSVESKQ 3j44 D 9.00 BS01 NUC 1 1 R27 R32 R33 S38 W39 T40 H41 I43 Q44 P45 Q46 G47 R48 D49 A52 K54 R55 R56 V57 E59 N60 K63 G64 H65 S66 M67 A68 R69 V70 E71 R72 K74 T75 P77 R78 Y79 F82 P84 F85 A86 R87 G88 G89 R90 R91 T92 H93 P95 K96 V97 E98 K99 I100 W102 E103 D104 N106 K107 K108 E109 K110 R111 L112 R130 G131 K153 T154 R155 R158 R172 S177 V179 R180 A181 G182 K183 K185 M186 R187 R189 R190 K192 K193 A194 K195 G206 L209 R212 N213 D223 N224 L225 G226 E228 H229 P232 H235 Y254 R27 R32 R33 S38 W39 T40 H41 I43 Q44 P45 Q46 G47 R48 D49 A52 K54 R55 R56 V57 E59 N60 K63 G64 H65 S66 M67 A68 R69 V70 E71 R72 K74 T75 P77 R78 Y79 F82 P84 F85 A86 R87 G88 G89 R90 R91 T92 H93 P95 K96 V97 E98 K99 I100 W102 E103 D104 N106 K107 K108 E109 K110 R111 L112 R130 G131 K153 T154 R155 R158 R172 S177 V179 R180 A181 G182 K183 K185 M186 R187 R189 R190 K192 K193 A194 K195 G206 L209 R212 N213 D223 N224 L225 G226 E228 H229 P232 H235 Y254 MKVKVFDLNGQPVGEIELPKVFFTPFRPDLIRRAVIASWTHRIQPQGRDPMAGKRRVTENIGKGHSMARVERLKTPPRYAAFVPFARGGRRTHPPKVEKIIWEDINKKEKRLALMSAIAATANYDLVRARGHIIDNVPQLPLIVVDDLQKVQKTRETREIFKKLGIWDDIVRAKEKSGVRAGKGKMRGRRYKKAKGPLIVVGKNEGIVLGARNHPGVDVVVVDNLGVEHLAPGTHPGRLTVWTVSAIERLRELYG 3j44 d 9.00 BS01 NUC 1 1 M1 K2 P3 M4 Y5 R6 R8 S9 R11 R12 Y14 R16 T17 P18 R21 V22 V23 H25 F26 E27 R28 K29 K30 P31 I33 A34 H35 A37 R41 L43 N44 G45 I46 P47 R48 R50 P51 V52 E53 R55 K56 P58 K59 T60 K61 K62 R63 P64 E65 R66 P67 M68 H70 P73 R74 R77 M1 K2 P3 M4 Y5 R6 R8 S9 R11 R12 Y14 R16 T17 P18 R21 V22 V23 H25 F26 E27 R28 K29 K30 P31 I33 A34 H35 A37 R41 L43 N44 G45 I46 P47 R48 R50 P51 V52 E53 R55 K56 P58 K59 T60 K61 K62 R63 P64 E65 R66 P67 M68 H70 P73 R74 R77 MKPMYRSRSWRRKYVRTPGGRVVIHFERKKPKIAHCAMCGRPLNGIPRGRPVEMRKLPKTKKRPERPMPHLCPRCMRKVMKEQIRAQLS 3j44 E 9.00 BS01 NUC 1 1 N31 G33 V34 R59 K60 A61 K62 K63 N65 R66 D67 F68 K79 S106 F107 D108 E109 H110 N112 C114 G116 E118 D138 C140 T142 K154 R157 N31 G33 V34 R59 K60 A61 K62 K63 N65 R66 D67 F68 K79 S106 F107 D108 E109 H110 N112 C114 G116 E118 D138 C140 T142 K154 R157 MAVEIPNKEQILADWEAHPMRRPRIEKVTINIGVGESGERLTKAEIMLQQLTGQKPIRRKAKKTNRDFGIRRGEPIAVKVTLRGPKAYELLKRLLAAVDNRLKASSFDEHGNVCFGIEEHINIPGVEYDPEIGIFGMDVCVTLERPGFRVARRKRKRAKIPTRHKLTKEEGMVYMMEEFGVEIVEG 3j44 E 9.00 BS02 NUC 3 1 H18 R21 R24 E26 Q54 K55 P56 I57 K79 V80 T81 R83 P146 G147 R149 V150 R152 R153 K154 K156 A158 I160 T162 R163 H164 H18 R21 R24 E26 Q54 K55 P56 I57 K79 V80 T81 R83 P146 G147 R149 V150 R152 R153 K154 K156 A158 I160 T162 R163 H164 MAVEIPNKEQILADWEAHPMRRPRIEKVTINIGVGESGERLTKAEIMLQQLTGQKPIRRKAKKTNRDFGIRRGEPIAVKVTLRGPKAYELLKRLLAAVDNRLKASSFDEHGNVCFGIEEHINIPGVEYDPEIGIFGMDVCVTLERPGFRVARRKRKRAKIPTRHKLTKEEGMVYMMEEFGVEIVEG 3j44 e 9.00 BS01 NUC 1 1 M1 G2 S3 G4 T5 A6 T7 F8 K10 R11 N12 S13 T14 P15 T16 H17 I18 R19 R21 R22 G24 R25 V26 Y28 K31 K32 A36 A37 F40 R42 S43 R44 R45 L46 R47 K48 Y49 R50 W51 K53 K54 K56 K57 K59 N60 H62 M1 G2 S3 G4 T5 A6 T7 F8 K10 R11 N12 S13 T14 P15 T16 H17 I18 R19 R21 R22 G24 R25 V26 Y28 K31 K32 A36 A37 F40 R42 S43 R44 R45 L46 R47 K48 Y49 R50 W51 K53 K54 K56 K57 K59 N60 H62 MGSGTATFGKRNSTPTHIRCRRCGRVSYNVKKGYCAACGFGRSRRLRKYRWSKKWKKKKNAH 3j44 F 9.00 BS01 NUC 1 1 M1 P2 V3 R37 F40 W41 R61 R62 K63 A66 I67 R69 T70 H74 N77 Y88 H96 L114 E116 K117 A118 R120 K123 K144 E145 G148 Q149 A152 Q156 R159 T161 W163 D164 R165 R166 I167 F168 K177 I182 M1 P2 V3 R37 F40 W41 R61 R62 K63 A66 I67 R69 T70 H74 N77 Y88 H96 L114 E116 K117 A118 R120 K123 K144 E145 G148 Q149 A152 Q156 R159 T161 W163 D164 R165 R166 I167 F168 K177 I182 MPVDAWIREEVEIPEGVEVTVEGYKVKVKGPKGELEREFFWPGIQIFTEDGNVVIYKDFPRRKDVAIARTFAAHIRNMIKGVTEGFTYKLKVVYSHFPISVKVQGDEVIIENFLGEKAPRKAKILPGVTVKVRGQEIIVEGIDKEAVGQTAANIEQATRITKWDRRIFQDGIYIVEKAGKPITF 3j44 G 9.00 BS01 NUC 1 1 K34 G35 T36 N37 E38 K41 R45 D58 I62 K83 I92 E93 V94 A95 A96 A97 K34 G35 T36 N37 E38 K41 R45 D58 I62 K83 I92 E93 V94 A95 A96 A97 MAKPSYVKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVIIAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVAAASVAIIEPGKARDLVEEIAMKVKELMK 3j44 g 9.00 BS01 NUC 1 1 R10 F12 K14 L18 R19 G21 A22 T23 P25 W26 K29 K30 R32 K33 G35 K37 R38 L39 R40 P41 K42 A43 K44 E45 R47 R8 F10 K12 L16 R17 G19 A20 T21 P23 W24 K27 K28 R30 K31 G33 K35 R36 L37 R38 P39 K40 A41 K42 E43 R45 RFPEAEARIFKKYVCLRCGATNPWGAKKCRKCGYKRLRPKAKEPR 3j44 H 9.00 BS01 NUC 1 1 M1 P2 K3 Q4 E7 L9 P19 M49 Q50 P52 P72 T73 S74 K78 E84 K85 G86 P90 K91 K110 Q113 M114 L115 L117 K124 E125 G128 T129 L131 S132 M133 G134 M1 P2 K3 Q4 E7 L9 P19 M49 Q50 P52 P72 T73 S74 K78 E84 K85 G86 P90 K91 K110 Q113 M114 L115 L117 K124 E125 G128 T129 L131 S132 M133 G134 MPKQVVEVLVEGGKATPGPPLGPAIGPLGLNVKQVVDKINEATKDFAGMQVPVKIIVDPVTKQFEIEVGVPPTSQLIKKELGLEKGSGEPKHNIVGNLTMEQVIKIAKMKKDQMLALTLKAAAKEVIGTALSMG 3j44 I 9.00 BS01 NUC 1 1 I10 G12 R13 S16 K17 A19 K20 T39 R42 K50 T53 E54 L55 R56 T57 L58 N60 P61 R62 R63 G64 P65 F66 Y67 P68 K69 R70 E73 R76 R77 T78 R80 M82 W85 K86 T87 D88 R89 R91 F94 K95 L112 I115 I116 E117 H119 V120 S121 S124 R125 F137 G139 K141 I10 G12 R13 S16 K17 A19 K20 T39 R42 K50 T53 E54 L55 R56 T57 L58 N60 P61 R62 R63 G64 P65 F66 Y67 P68 K69 R70 E73 R76 R77 T78 R80 M82 W85 K86 T87 D88 R89 R91 F94 K95 L112 I115 I116 E117 H119 V120 S121 S124 R125 F137 G139 K141 MRIINAEGLILGRLASKVAKMLLEGEEVVIVNAEKAVITGNRDVIFKKYKQRTELRTLTNPRRGPFYPKRSDEIVRRTIRGMLPWKTDRGRKAFKRLKVYVGIPKEFQGKELETIIEAHVSRLSRPKYVTVGEVAKFLGGKF 3j44 i 9.00 BS01 NUC 1 1 K6 V7 G8 S9 G11 R12 G14 A15 R16 Y17 G18 L19 I21 R22 R23 R33 C41 R43 R48 S50 T51 K58 C59 K1 V2 G3 S4 G6 R7 G9 A10 R11 Y12 G13 L14 I16 R17 R18 R28 C36 R38 R43 S45 T46 K53 C54 KVGSAGRFGARYGLKIRRRVAAVEAKMRQKHTCPVCGRKAVKRISTGIWQCQKCGATFAGGAYLPVTPAGKAVRRITE 3j44 J 9.00 BS01 NUC 1 1 R10 G11 V12 S13 V15 R16 P17 T18 R19 A20 L21 P22 A25 Y26 I41 V43 V44 E45 Y46 H47 G48 T49 R50 R51 R52 L53 V63 T65 K67 H75 R86 K87 E88 R90 R96 N102 R129 R1 G2 V3 S4 V6 R7 P8 T9 R10 A11 L12 P13 A16 Y17 I32 V34 V35 E36 Y37 H38 G39 T40 R41 R42 R43 L44 V54 T56 K58 H66 R77 K78 E79 R81 R87 N93 R120 RGVSAVRPTRALPVGAYLTVADNSGAKVIQIIGVVEYHGTRRRLASAGVGDMVVATVKKGRPDMRHQVVRAVIIRQRKEYRRLDGMRVKFEDNAAVIVTPEGVPRGTEIRGPVAREAAERWVRIGSIASIIV 3j44 j 9.00 BS01 NUC 1 1 M1 K2 Y3 R8 T9 Y10 K15 K16 H17 V25 K26 K27 R28 R30 E32 L33 S34 A35 G36 R38 R39 R41 R42 L44 K45 G46 Y47 G48 G49 F50 R52 P55 E56 G57 R58 E59 K60 P61 V62 K63 K64 D66 R68 K76 A77 H78 T79 R80 G81 R82 F84 R85 K87 K88 M1 K2 Y3 R8 T9 Y10 K15 K16 H17 V25 K26 K27 R28 R30 E32 L33 S34 A35 G36 R38 R39 R41 R42 L44 K45 G46 Y47 G48 G49 F50 R52 P55 E56 G57 R58 E59 K60 P61 V62 K63 K64 D66 R68 K76 A77 H78 T79 R80 G81 R82 F84 R85 K87 K88 MKYPKQIRTYCPFCKKHTIHKVERVKKRPRSELSAGQRRFRRILKGYGGFPRPKPEGREKPVKKLDLRFRCTECGKAHTRGRGFRVKKFELVEG 3j44 K 9.00 BS01 NUC 1 1 G15 R16 R17 K42 K44 R46 R47 N49 K51 G13 R14 R15 K40 K42 R44 R45 N47 K49 AIDVGRIAVVIAGRRAGQKVVVVDIIDKNFVLVTGAGLNKVKRRRMNIKHIEPLPQKIDIPRGASDEEVRAALEKAGISLA 3j44 k 9.00 BS01 NUC 1 1 E6 W7 K8 E11 S31 M33 P34 A35 S39 R42 R46 L52 R53 V54 S55 R56 N57 E61 I83 E84 G85 G86 A87 K113 E1 W2 K3 E6 S26 M28 P29 A30 S34 R37 R41 L47 R48 V49 S50 R51 N52 E56 I78 E79 G80 G81 A82 K108 EWKKKEVEELANLIKSYPVVALVDVSSMPAYPLSQMRRLIRENNGLLRVSRNTLIELAIKKVAQELGKPELEKLINYIEGGAGILVTTMNPFKLYKFLQQNRQPAPAKPGAKVPKDVVIPAGPTSLAPGPIVGQMQAMGIPARIERGKVTIQKDTVVLKAGEEITPELANILNALGIQPLEVGLDLLAVYEDGIIYTPDVLAIDESEYINML 3j44 L 9.00 BS01 NUC 1 1 M1 I2 R3 R4 R5 K6 K7 R9 K10 L11 R12 S14 H15 T16 H17 G18 W19 G20 C21 K22 K23 K24 H25 R26 G27 G28 G29 S30 K31 G32 R34 G35 M36 G38 T39 G40 K41 R42 N43 K44 S45 W47 T48 W49 T50 K52 Y53 H57 L58 G59 R61 G62 F63 R65 P66 E68 V69 E72 V73 V75 N77 K79 D82 E83 H84 K111 L113 G114 T115 G116 K117 S130 P131 K132 K136 M1 I2 R3 R4 R5 K6 K7 R9 K10 L11 R12 S14 H15 T16 H17 G18 W19 G20 C21 K22 K23 K24 H25 R26 G27 G28 G29 S30 K31 G32 R34 G35 M36 G38 T39 G40 K41 R42 N43 K44 S45 W47 T48 W49 T50 K52 Y53 H57 L58 G59 R61 G62 F63 R65 P66 E68 V69 E72 V73 V75 N77 K79 D82 E83 H84 K111 L113 G114 T115 G116 K117 S130 P131 K132 K136 MIRRRKKVRKLRGSHTHGWGCKKKHRGGGSKGGRGMAGTGKRNKSKWTWTIKYAPDHLGKRGFSRPPEVQREVRVVNLKFIDEHLDELMQMGIAYEEGGKIIVDVTQFADKVLGTGKLTRPLVIKARAFSPKAEEKIKAAGGEAVLV 3j44 M 9.00 BS01 NUC 1 1 M1 Y4 R8 K12 S13 P14 K15 K16 M27 I28 R31 R32 V35 R38 R41 R44 R47 R49 A50 L51 Q54 A55 K56 Q57 R67 K68 G69 R71 K72 R73 P74 R75 W76 G78 G79 R80 K81 P82 K84 M85 V88 K89 Y90 S91 P92 K93 K94 S95 L96 W98 K103 R106 K107 P109 N110 N115 W118 D122 G123 M124 K126 D134 H136 H137 P138 V139 S142 D143 P144 K145 W148 K152 H153 H154 K155 G156 R157 F159 R160 L162 S164 K167 K168 G169 R170 G171 L172 R173 N174 K175 G176 K177 G178 E180 K181 R183 P184 S185 I186 R187 A188 E190 G191 K192 K194 M1 Y4 R8 K12 S13 P14 K15 K16 M27 I28 R31 R32 V35 R38 R41 R44 R47 R49 A50 L51 Q54 A55 K56 Q57 R67 K68 G69 R71 K72 R73 P74 R75 W76 G78 G79 R80 K81 P82 K84 M85 V88 K89 Y90 S91 P92 K93 K94 S95 L96 W98 K103 R106 K107 P109 N110 N115 W118 D122 G123 M124 K126 D134 H136 H137 P138 V139 S142 D143 P144 K145 W148 K152 H153 H154 K155 G156 R157 F159 R160 L162 S164 K167 K168 G169 R170 G171 L172 R173 N174 K175 G176 K177 G178 E180 K181 R183 P184 S185 I186 R187 A188 E190 G191 K192 K194 MGMYKYIREAWKSPKKSYVGELLKQRMIKWRREPVVVRIERPTRLDRARALGYQAKQGYVIVRVRVRKGGRKRPRWKGGRKPSKMGQVKYSPKKSLQWIAEEKAARKFPNLEVLNSYWVGEDGMYKWFEVIMVDPHHPVIKSDPKIAWIALKHHKGRVFRGLTSAGKKGRGLRNKGKGAEKVRPSIRANEGKGK 3j44 N 9.00 BS01 NUC 1 1 R4 P5 A6 K7 I8 R10 K14 P15 A16 Y17 T18 R19 R20 E21 Y22 R24 F34 D35 R58 N60 A64 Q68 R71 K75 R87 Y89 F91 R95 N97 M99 T101 G102 R103 K104 A105 R107 Y108 G109 N110 G111 M112 R113 R114 P115 F116 G117 R125 R150 R151 M154 K155 F156 P157 K159 Y161 R163 R2 P3 A4 K5 I6 R8 K12 P13 A14 Y15 T16 R17 R18 E19 Y20 R22 F32 D33 R56 N58 A62 Q66 R69 K73 R85 Y87 F89 R93 N95 M97 T99 G100 R101 K102 A103 R105 Y106 G107 N108 G109 M110 R111 R112 P113 F114 G115 R123 R148 R149 M152 K153 F154 P155 K157 Y159 R161 LRPAKIDRYVDKPAYTRREYIRGAPGPKITIFDMGNPAGDFEFEVSLHTAEPVQIRQNALEAARQQVNRYLQKNVGRSNYHFKIRVYPFQVLRENPMATGRKADRYGNGMRRPFGKPIGLAARLKKDQKILSIRVNRQHLKFAIEGARRAAMKFPCKCYYRIYDKEGN 3j44 O 9.00 BS01 NUC 1 1 M1 A2 R6 Y7 R8 R14 G17 K18 T19 Y21 R22 K23 K26 L27 K29 S30 I103 I106 H109 P110 P111 F118 P132 H133 S134 E136 I137 M1 A2 R6 Y7 R8 R14 G17 K18 T19 Y21 R22 K23 K26 L27 K29 S30 I103 I106 H109 P110 P111 F118 P132 H133 S134 E136 I137 MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQDEEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFE 3j44 O 9.00 BS02 NUC 3 1 M1 H3 G4 P5 P10 R12 R13 T19 R24 R34 V36 R38 S40 L41 N42 H43 Q47 I49 G55 D56 R57 T58 S61 H63 R65 E66 R69 H76 N79 T80 H109 P110 V112 R113 G114 S115 S116 R143 H148 I149 Y152 L156 E158 Q159 F168 G170 Y171 L172 V173 K174 M1 H3 G4 P5 P10 R12 R13 T19 R24 R34 V36 R38 S40 L41 N42 H43 Q47 I49 G55 D56 R57 T58 S61 H63 R65 E66 R69 H76 N79 T80 H109 P110 V112 R113 G114 S115 S116 R143 H148 I149 Y152 L156 E158 Q159 F168 G170 Y171 L172 V173 K174 MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQDEEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFE 3j44 P 9.00 BS01 NUC 1 1 M1 K2 R3 T4 G5 T7 D8 R16 R19 K20 N23 V27 K28 I29 D32 R36 R39 P40 R41 R42 Q43 E46 N48 V49 S50 K51 R54 Y55 N57 L69 G70 K73 K84 S86 E87 T88 G113 S114 G115 V116 R117 I118 M119 E120 M1 K2 R3 T4 G5 T7 D8 R16 R19 K20 N23 V27 K28 I29 D32 R36 R39 P40 R41 R42 Q43 E46 N48 V49 S50 K51 R54 Y55 N57 L69 G70 K73 K84 S86 E87 T88 G113 S114 G115 V116 R117 I118 M119 E120 MKRTGPTDPNLRRLIRYLRKKSNEYGVKIWKDVAWRLERPRRQRAEVNVSKINRYANDGEMIVVPGSVLGAGKLEKKVIVAAWKFSETARRKIIEAGGEAITIEELIERNPTGSGVRIME 3j44 R 9.00 BS01 NUC 1 1 Q3 K4 A5 H6 S7 F8 R9 R10 K11 T12 R13 K14 K15 L16 S17 H19 P20 R23 G24 L25 R40 H42 V44 P47 S48 H50 K51 D55 R57 H59 G60 R61 T62 R69 E71 K78 S81 K82 K84 T85 F87 H89 Q96 K97 Q1 K2 A3 H4 S5 F6 R7 R8 K9 T10 R11 K12 K13 L14 S15 H17 P18 R21 G22 L23 R38 H40 V42 P45 S46 H48 K49 D53 R55 H57 G58 R59 T60 R67 E69 K76 S79 K80 K82 T83 F85 H87 Q94 K95 QKAHSFRRKTRKKLSKHPRRRGLPPLTRFLQEFEVGQRVHIVIEPSYHKGMPDPRFHGRTGTVVGKRGEAYIVEIKDGSKVKTLFIHPVHLRPQK 3j44 R 9.00 BS02 NUC 3 1 R21 T29 R19 T27 QKAHSFRRKTRKKLSKHPRRRGLPPLTRFLQEFEVGQRVHIVIEPSYHKGMPDPRFHGRTGTVVGKRGEAYIVEIKDGSKVKTLFIHPVHLRPQK 3j44 V 9.00 BS01 NUC 1 1 T18 G19 K20 C33 R35 K36 E38 R39 Y40 M43 R45 K49 K51 W52 K54 Q57 L61 T18 G19 K20 C33 R35 K36 E38 R39 Y40 M43 R45 K49 K51 W52 K54 Q57 L61 MARWNVCSYCGKPFEPGTGKMYVRNDGRVLFFCSRKCERYYFMGRNPRKLKWTKAYQEARLQRGGE 3j44 Y 9.00 BS01 NUC 1 1 R12 V13 N14 V15 R17 R20 D21 T22 M25 R27 H29 R30 V31 N32 H33 S42 Y43 M46 K49 K70 R71 R73 L74 I75 G76 N77 K108 K114 P115 V116 R118 L119 H120 P121 P122 R123 G124 G125 F126 R127 S129 K130 K131 L155 R12 V13 N14 V15 R17 R20 D21 T22 M25 R27 H29 R30 V31 N32 H33 S42 Y43 M46 K49 K70 R71 R73 L74 I75 G76 N77 K108 K114 P115 V116 R118 L119 H120 P121 P122 R123 G124 G125 F126 R127 S129 K130 K131 L155 MAKLAVIRIRGRVNVKRPVRDTLAMLRLHRVNHCVIVDDTPSYLGMLQKAKDYITWGEINAETLAKLIRKRGRLIGNKPVTDEYVKEKLGMTIEEFAQKVVNGEMSLKDLPNLKPVFRLHPPRGGFRGSKKRSFKEGGALGYRGEKINELIERML 3j44 Y 9.00 BS02 NUC 3 1 Q48 K51 D52 Y53 K131 S133 K135 E136 Q48 K51 D52 Y53 K131 S133 K135 E136 MAKLAVIRIRGRVNVKRPVRDTLAMLRLHRVNHCVIVDDTPSYLGMLQKAKDYITWGEINAETLAKLIRKRGRLIGNKPVTDEYVKEKLGMTIEEFAQKVVNGEMSLKDLPNLKPVFRLHPPRGGFRGSKKRSFKEGGALGYRGEKINELIERML 3j44 Z 9.00 BS01 NUC 1 1 L18 G19 S20 N21 E22 R25 A41 P42 I45 L74 K76 P77 F78 V80 L18 G19 S20 N21 E22 R25 A41 P42 I45 L74 K76 P77 F78 V80 MDLAFELRKAMETGKVVLGSNETIRLAKTGGAKLIIVAKNAPKEIKDDIYYYAKLSDIPVYEFEGTSVELGTLLGKPFVVASLAIVDPGESKILAIAKR 3j45 y 9.50 BS01 NUC 1 1 K250 Q253 G254 R255 R256 V257 K245 Q248 G249 R250 R251 V252 P0AGA2 GLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKG 3j45 y 9.50 BS02 NUC 2 1 Y248 A249 K250 R251 Q252 F352 P354 R357 Y243 A244 K245 R246 Q247 F347 P349 R352 P0AGA2 GLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKG 3j45 T 9.50 BS01 NUC 1 1 K36 K68 Q72 R73 R76 R77 S78 K36 K68 Q72 R73 R76 R77 S78 P0ADZ0 MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE 3j45 T 9.50 BS02 NUC 2 1 H15 S17 E18 K19 S21 M24 T29 N59 T60 L61 K64 K66 V67 K68 R69 H70 K82 Y84 H15 S17 E18 K19 S21 M24 T29 N59 T60 L61 K64 K66 V67 K68 R69 H70 K82 Y84 P0ADZ0 MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE 3j45 U 9.50 BS01 NUC 1 1 R5 R6 S29 K90 K91 R5 R6 S29 K90 K91 P60624 AAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK 3j45 Y 9.50 BS01 NUC 1 1 M1 K2 L6 Q38 S40 H41 L43 K44 R47 R48 A51 R52 K54 T55 L56 N58 E59 K60 M1 K2 L6 Q38 S40 H41 L43 K44 R47 R48 A51 R52 K54 T55 L56 N58 E59 K60 P0A7M6 MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA 3j46 y 10.10 BS02 NUC 2 1 A249 K250 R251 Q252 G355 R357 P358 A244 K245 R246 Q247 G350 R352 P353 P0AGA2 GLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFCGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKG 3j46 n 10.10 BS01 NUC p 1 A99 G100 A99 G100 AKKIWLALAGLVLAFSASCAQYEDGSSGELERQHTFALHQRSISGDGDSPHSYHSLPEGVKMTKYLQEQKLAVAAVAAQADLELFSTPVWISQAQGIRAG 3j46 5 10.10 BS01 NUC 4 1 M1 A2 K3 L4 T5 K6 R7 M8 R12 K14 V15 D16 A17 L33 K37 F38 E40 D43 A45 D51 R53 R60 R71 R74 K105 K106 G107 E108 M109 N110 F111 D112 G128 V130 L131 G132 P133 R134 G135 R162 R164 N165 D166 K167 N168 H172 T174 S215 T217 M218 G219 A220 M1 A2 K3 L4 T5 K6 R7 M8 R12 K14 V15 D16 A17 L33 K37 F38 E40 D43 A45 D51 R53 R60 R71 R74 K105 K106 G107 E108 M109 N110 F111 D112 G128 V130 L131 G132 P133 R134 G135 R162 R164 N165 D166 K167 N168 H172 T174 S215 T217 M218 G219 A220 P0A7L0 MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN 3j46 T 10.10 BS01 NUC 1 1 R12 K36 K68 Q72 R73 I74 G75 R76 R77 D79 R12 K36 K68 Q72 R73 I74 G75 R76 R77 D79 P0ADZ0 MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE 3j46 T 10.10 BS02 NUC 2 1 H15 K19 A20 S21 M24 T29 K40 N59 T60 L61 K64 K66 V67 R69 H70 R77 K82 Y84 H15 K19 A20 S21 M24 T29 K40 N59 T60 L61 K64 K66 V67 R69 H70 R77 K82 Y84 P0ADZ0 MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE 3j46 U 10.10 BS01 NUC 1 1 I4 R5 R6 V27 S29 K90 K91 I4 R5 R6 V27 S29 K90 K91 P60624 AAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK 3vxm A 2.50 BS01 III C 1 Y7 Y59 E63 K66 H70 T73 N77 I80 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q155 Q156 Y159 T163 Y171 Y7 Y59 E63 K66 H70 T73 N77 I80 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q155 Q156 Y159 T163 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxm D 2.50 BS01 III C 1 G28 T30 P31 Y32 P96 Y102 G28 T30 P31 Y32 P96 Y102 AQSVTQPDIHITVSEGASLELRCNYSYGATPYLFWYVQSPGQGLQLLLKYFSGDTLVQGIKGFEAEFKRSQSSFNLRKPSVHWSDAAEYFCAVGAPSGAGSYQLTFGKGTKLSVIPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSII 3vxm E 2.50 BS01 III C 1 P95 T96 S97 G98 I99 Y100 P95 T96 S97 G98 I99 Y100 DTEVTQTPKHLVMGMTNKKSLKCEQHMGHRAMYWYKQKAKKPPELMFVYSYEKLSINESVPSRFSPECPNSSLLNLHLHALQPEDSALYLCASSPTSGIYEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3vxm E 2.50 BS02 CO E 1 H10 H153 E155 H10 H153 E155 DTEVTQTPKHLVMGMTNKKSLKCEQHMGHRAMYWYKQKAKKPPELMFVYSYEKLSINESVPSRFSPECPNSSLLNLHLHALQPEDSALYLCASSPTSGIYEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3vxm E 2.50 BS03 CO E 2 E24 H26 E24 H26 DTEVTQTPKHLVMGMTNKKSLKCEQHMGHRAMYWYKQKAKKPPELMFVYSYEKLSINESVPSRFSPECPNSSLLNLHLHALQPEDSALYLCASSPTSGIYEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3vxn A 1.95 BS01 III C 1 M5 Y7 S9 F22 M45 Y59 E62 E63 K66 V67 H70 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q156 Y159 Y171 M5 Y7 S9 F22 M45 Y59 E62 E63 K66 V67 H70 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxo A 2.61 BS01 III C 1 Y7 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 Y171 Y7 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxo D 2.61 BS01 III F 1 Y7 Y59 E62 E63 K66 V67 H70 N77 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 Y171 Y7 Y59 E62 E63 K66 V67 H70 N77 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxp A 2.50 BS01 III C 1 Y7 F22 M45 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q155 Q156 Y159 T163 Y171 Y7 F22 M45 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q155 Q156 Y159 T163 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxp D 2.50 BS01 III F 1 Y7 M45 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 Y171 Y7 M45 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxr A 2.40 BS01 III C 1 Y7 A24 M45 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q156 Y159 Y171 Y7 A24 M45 Y59 E62 E63 K66 V67 H70 T73 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxr D 2.40 BS01 III C 1 Y31 R93 D95 Y98 Y31 R93 D95 Y98 KQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVRMDSSYKLIFGSGTRLLVRPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSII 3vxr E 2.40 BS01 III C 1 R31 W97 G100 R30 W96 G99 TGVSQNPRHKITKRGQNVTFRCDPISEHNRLYWYRQTLGQGPEFLTYFQNEAQLEKSRLLSDRFSAERPKGSFSTLEIQRTEQGDSAMYLCASSSWDTGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3vxs A 1.80 BS01 III C 1 M5 Y7 A24 M45 E63 K66 V67 H70 T73 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q156 Y159 T163 D166 Y171 M5 Y7 A24 M45 E63 K66 V67 H70 T73 N77 I80 Y84 L95 M97 F99 H114 Y116 Y123 T143 K146 W147 V152 Q156 Y159 T163 D166 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxs D 1.80 BS01 III C 1 Y31 R93 D95 S97 Y98 Y31 R93 D95 S97 Y98 KQEVTQIPAALSVPEGENLVLNCSFTDSAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVRMDSSYKLIFGSGTRLLVRPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPE 3vxs E 1.80 BS01 III C 1 R31 S96 W97 D98 G100 R30 S95 W96 D97 G99 TGVSQNPRHKITKRGQNVTFRCDPISEHNRLYWYRQTLGQGPEFLTYFQNEAQLEKSRLLSDRFSAERPKGSFSTLEIQRTEQGDSAMYLCASSSWDTGELFFGEGSRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3vxu A 2.70 BS01 III C 1 M5 Y7 E63 K66 H70 N77 Y84 M97 F99 Y116 Y123 T143 W147 Q155 Q156 Y159 Y171 M5 Y7 E63 K66 H70 N77 Y84 M97 F99 Y116 Y123 T143 W147 Q155 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxu E 2.70 BS01 III C 1 N28 E30 Y31 G95 A96 S97 H98 N28 E30 Y31 G95 A96 S97 H98 EAQVTQNPRYLITVTGKKLTVTCSQNMNHEYMSWYRQDPGLGLRQIYYSMNVEVTDKGDVPEGYKVSRKEKRNFPLILESPSPNQTSLYFCASSGASHEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3vxu F 2.70 BS01 III H 1 M5 Y7 E62 E63 K66 H70 N77 I80 Y84 F99 H114 Y123 T143 K146 W147 Q156 Y159 Y171 M5 Y7 E62 E63 K66 H70 N77 I80 Y84 F99 H114 Y123 T143 K146 W147 Q156 Y159 Y171 P05534 GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW 3vxu I 2.70 BS01 III H 1 Y92 N93 G96 Y91 N92 G95 KEVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMSIYSNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLWGTYNQGGKLIFGQGTELSVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 3vxu J 2.70 BS01 III H 1 E30 Y31 M50 H98 E30 Y31 M50 H98 EAQVTQNPRYLITVTGKKLTVTCSQNMNHEYMSWYRQDPGLGLRQIYYSMNVEVTDKGDVPEGYKVSRKEKRNFPLILESPSPNQTSLYFCASSGASHEQYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 3w57 A 1.66 BS01 CA A 1 D35 D41 D88 E89 D90 D17 D23 D70 E71 D72 E2FYL5 24070258 HMQLRLYNLRVRGLPSDLMGITDGYVKVFCGSANLGETSVNHNNANPWWTEEFSHFKAQENDILRLEVHDEDTFFDDLLGVCQRQIKVGTHEHDCYLKEGGTLHYMYTLSV 3w57 A 1.66 BS02 CA A 2 D35 D88 D90 D95 D17 D70 D72 D77 E2FYL5 24070258 HMQLRLYNLRVRGLPSDLMGITDGYVKVFCGSANLGETSVNHNNANPWWTEEFSHFKAQENDILRLEVHDEDTFFDDLLGVCQRQIKVGTHEHDCYLKEGGTLHYMYTLSV 3w57 A 1.66 BS03 CA A 3 I39 D41 N61 I21 D23 N43 E2FYL5 24070258 HMQLRLYNLRVRGLPSDLMGITDGYVKVFCGSANLGETSVNHNNANPWWTEEFSHFKAQENDILRLEVHDEDTFFDDLLGVCQRQIKVGTHEHDCYLKEGGTLHYMYTLSV 3wd9 A 2.50 BS01 QPC A 1 S282 M347 N395 F414 S442 Q443 F446 L502 M503 F506 E509 S129 M194 N242 F261 S289 Q290 F293 L336 M337 F340 E343 3.1.4.17 Q07343 24094436 SRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPCQGLMEKFQFELT 3wd9 B 2.50 BS01 QPC B 1 Y233 H234 H278 G280 V281 S282 M347 N395 I410 E413 F414 Q417 S442 Q443 F446 L502 M503 F506 Y80 H81 H125 G127 V128 S129 M194 N242 I257 E260 F261 Q264 S289 Q290 F293 L336 M337 F340 3.1.4.17 Q07343 24094436 SRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPCQGLMEKFQFELT 3wg5 B 2.40 BS01 III C 1 G65 R66 A67 S97 Y101 A119 C120 R121 P122 I123 L124 Y126 I139 F143 G47 R48 A49 S79 Y83 A101 C102 R103 P104 I105 L106 Y108 I121 F125 O59179 LAKNIVYVAQIKGQITSYTYDQFDRYITIAEQDNAEAIIIELDTPGGRADAMMNIVQRIQQSKIPVIIYVYPPGASAASAGTYIALGSHLIAMAPGTSIGACRPILGYSQNGSIIEAPPAITNYFIAYIKSLAQESGRNATIAEEFITKDLSLTPEEALKYGVIEVVARDINELLKKSNGMKTKIPVNGRYVTLNFTNVEVRYLAPSFKDKLISYITDL 3wh2 A 1.30 BS01 CA A 1 E169 N171 N193 D194 E92 N94 N116 D117 Q9ULY5 24101491 NCCPLNWEYFQSSCYFFSTDTKSWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVG 3wh2 A 1.30 BS02 CA A 2 V117 N119 E123 E206 V40 N42 E46 E129 Q9ULY5 24101491 NCCPLNWEYFQSSCYFFSTDTKSWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVG 3wh2 A 1.30 BS03 FLC A 1 E169 N171 N172 R183 N193 D194 V195 T196 L199 E92 N94 N95 R106 N116 D117 V118 T119 L122 Q9ULY5 24101491 NCCPLNWEYFQSSCYFFSTDTKSWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVG 3whd A 2.29 BS01 CA A 1 E173 D175 N176 N195 D196 E103 D105 N106 N125 D126 Q8WXI8 24101491 HAKLKCIKSTWNCCPIDWRAFQSNCYFPLTDNKTWAESERNCSGMGAHLMTISTEAEQNFIIQFLDRRLSYFLGLRDENAKGQWRWVDQTPFNPRRVFWHKNEPDNSQGENCVVLVYNQDKWAWNDVPCNFEASRICKIPGTTLN 3whd C 2.29 BS01 CA C 1 E173 D175 N195 D196 E106 D108 N128 D129 Q8WXI8 24101491 MHAKLKCIKEKSTWNCCPIDWRAFQSNCYFPLTDNKTWAESERNCSGMGAHLMTISTEAEQNFIIQFLDRRLSYFLGLRDENAKGQWRWVDQTPFNPRRVFWHKNEPDNSQGENCVVLVYNQDKWAWNDVPCNFEASRICKIPGTTLN 3wio A 2.10 BS01 H3M A 1 F186 V194 W205 Y209 F245 V269 S270 F133 V141 W152 Y156 F192 V216 S217 3.1.-.- Q10QA5 AKLLQILNVRVVGSGERVVVLSHGFGTDQSAWSRVLPYLTRDHRVVLYDLVCAGSVNPDHFDFRRYDNLDAYVDDLLAILDALRIPRCAFVGHSVSAMIGILASIRRPDLFAKLVLIGASPRFLNDSDYHGGFELEEIQQVFDAMGANYSAWATGYAPLAVGADVPAAVQEFSRTLFNMRPDISLHVCQTVFKTDLRGVLGMVRAPCVVVQTTRDVSVPASVAAYLKAHLGGRTTVEFLQTEGHLPHLSAPSLLAQVLRRALARY 3zcf A 1.65 BS01 HEC A 1 K13 C14 C17 H18 T28 G29 P30 L35 T40 G41 Y46 Y48 T49 N52 W59 L64 Y67 L68 T78 K79 M80 I81 F82 I85 L94 L98 K13 C14 C17 H18 T28 G29 P30 L35 T40 G41 Y46 Y48 T49 N52 W59 L64 Y67 L68 T78 K79 M80 I81 F82 I85 L94 L98 P99999 24099549 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE 3zcf B 1.65 BS01 HEC B 1 K13 C14 C17 H18 T28 G29 P30 L35 T40 G41 Y46 Y48 T49 N52 W59 L64 Y67 L68 T78 K79 M80 F82 I85 L94 K13 C14 C17 H18 T28 G29 P30 L35 T40 G41 Y46 Y48 T49 N52 W59 L64 Y67 L68 T78 K79 M80 F82 I85 L94 P99999 24099549 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE 3zoo C 1.35 BS01 HEM C 1 K13 C14 C17 H18 T28 G29 P30 T40 G41 Y48 T49 N52 W59 L64 Y67 L68 T78 K79 M80 F82 L94 L98 K13 C14 C17 H18 T28 G29 P30 T40 G41 Y48 T49 N52 W59 L64 Y67 L68 T78 K79 M80 F82 L94 L98 P99999 24099549 GDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE 4bfn A 1.32 BS01 GLC A 1 W47 Y83 N96 N101 W47 Y83 N96 N101 3.2.1.3 Q2VC81 24108499 ASIPSSASVQLDSYNYDGSTFSGKIYVKNIAYSKKVTVVYADGSDNWNNNGNIIAASFSGPISGSNYEYWTFSASVKGIKEFYIKYEVSGKTYYDNNNSANYQVST 4bfo A 1.18 BS01 GLC A 1 Y32 S33 K34 F58 W70 Y32 S33 K34 F58 W70 3.2.1.3 Q2VC81 24108499 ASIPSSASVQLDSYNYDGSTFSGKIYVKNIAYSKKVTVVYADGSDNWNNNGNIIAASFSGPISGSNYEYWTFSASVKGIKEFYIKYEVSGKTYYDNNNSANYQVST 4bfo A 1.18 BS02 GLC A 2 Y32 K34 F58 E68 Y32 K34 F58 E68 3.2.1.3 Q2VC81 24108499 ASIPSSASVQLDSYNYDGSTFSGKIYVKNIAYSKKVTVVYADGSDNWNNNGNIIAASFSGPISGSNYEYWTFSASVKGIKEFYIKYEVSGKTYYDNNNSANYQVST 4bqg A 1.90 BS01 50Q A 1 N51 A55 D93 M98 L107 F138 Y139 V150 W162 T184 V186 N36 A40 D78 M83 L92 F123 Y124 V135 W147 T169 V171 Q2VPJ6 24100158 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 4bqj A 2.00 BS01 XKL A 1 L48 N51 A55 K58 D93 I96 G97 M98 D102 N106 L107 G135 V136 G137 F138 T184 V186 L37 N40 A44 K47 D82 I85 G86 M87 D91 N95 L96 G124 V125 G126 F127 T173 V175 P07900 24100158 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 4bzb A 1.83 BS01 DGT A 1 Q149 L150 R164 R206 H215 H233 K312 Y315 D319 R366 Y374 Q375 Q37 L38 R52 R94 H103 H121 K194 Y197 D201 R248 Y256 Q257 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb A 1.83 BS02 DGT A 2 V156 F157 I325 R372 H376 K377 V44 F45 I207 R254 H258 K259 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb A 1.83 BS03 DGT A 3 Y155 V156 V378 R451 K455 Y43 V44 V260 R333 K337 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb A 1.83 BS04 DGT C 1 D330 R333 F337 R352 K354 N358 K523 D212 R215 F219 R234 K236 N240 K405 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb A 1.83 BS05 DGT D 1 V117 I118 N119 H125 V5 I6 N7 H13 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb A 1.83 BS06 DGT D 2 K116 V117 I118 D137 Q142 R145 F165 K4 V5 I6 D25 Q30 R33 F53 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb C 1.83 BS02 DGT B 4 V117 N119 H125 V5 N7 H13 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzb C 1.83 BS05 DGT C 1 V156 F157 R372 H376 K377 V44 F45 R254 H258 K259 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc A 2.88 BS01 T8T A 1 Q149 L150 R164 D207 H210 H215 H233 K312 Y315 D319 H370 Y374 Q375 Q36 L37 R51 D94 H97 H102 H120 K195 Y198 D202 H253 Y257 Q258 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc A 2.88 BS02 MN A 1 R164 H167 H206 D207 D311 R51 H54 H93 D94 D194 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc A 2.88 BS04 T8T A 3 Y155 V156 K377 V378 R451 Y42 V43 K260 V261 R334 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc A 2.88 BS06 T8T D 1 V117 N119 V4 N6 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc B 2.88 BS01 T8T B 1 Q149 L150 R164 D207 H210 H215 H233 D311 K312 Y315 D319 R366 H370 Y374 Q375 Q37 L38 R52 D95 H98 H103 H121 D191 K192 Y195 D199 R246 H250 Y254 Q255 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKRYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc B 2.88 BS03 T8T B 2 V156 F157 G324 I325 R372 H376 K377 V44 F45 G204 I205 R252 H256 K257 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKRYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc B 2.88 BS07 T8T D 1 D330 R333 F337 R352 K354 K523 D210 R213 F217 R232 K234 K401 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKRYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4bzc C 2.88 BS01 T8T A 4 R333 F337 R352 K354 N358 K523 R215 F219 R234 K236 N240 K405 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4c2m A 2.80 BS01 ZN A 1 C62 C65 C72 H75 C62 C65 C72 H75 2.7.7.6 P10964 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLSSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLQKDKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFANVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTAARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTPDIGVAVPNSKRLEEDNDEEQSHKKTKQAVSYDEPDEDEIETMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNAA 4c2m A 2.80 BS02 ZN A 2 C102 C105 C233 C236 C102 C105 C201 C204 2.7.7.6 P10964 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLSSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLQKDKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFANVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTAARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTPDIGVAVPNSKRLEEDNDEEQSHKKTKQAVSYDEPDEDEIETMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNAA 4c2m B 2.80 BS01 ZN B 1 C1104 C1107 C1128 C1131 C1092 C1095 C1116 C1119 2.7.7.6 P22138 PGQARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSNSGYLGNKLSVSVEQVSIAKPMSNDGVSSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKLIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 4c2m I 2.80 BS01 ZN I 1 C10 C13 C30 C33 C9 C12 C29 C32 P32529 SVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKSVVKTSLKKNELKDGATIKEKCPQCGNEEMNYHTLQLRSADEGATVFYTCTSCGYKFRTNN 4c3f A 1.72 BS01 7KW A 1 L251 A271 K273 E288 T316 E317 Y318 M319 G322 L371 L14 A34 K36 E51 T79 E80 Y81 M82 G85 L134 2.7.10.2 P06239 24117015 WEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRNLRAANILVSDTLSCKIADFGLARLIEDNEYTARFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 4c3i A 3.00 BS01 ZN A 1 C102 C105 C233 C236 C102 C105 C203 C206 2.7.7.6 P10964 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDMISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGTARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 4c3i A 3.00 BS02 ZN A 2 C62 C65 C72 H75 C62 C65 C72 H75 2.7.7.6 P10964 MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDMISTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFNVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGTARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNA 4c3i B 3.00 BS01 MG B 1 D784 D785 D769 D770 2.7.7.6 P22138 RTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEEISNSGYLGNKLSVSVEQVSIAKPMSNDSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASHTFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK 4c3i I 3.00 BS02 ZN I 2 C86 C89 C114 C85 C88 C113 P32529 SVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKSVVKTSLKKNELKDGATIKEKCPQCGNEEMNYHTLQLRSADEGATVFYTCTSCGYKFRTNN 4fb3 A 3.79 BS01 NUC C 1 N307 K308 T309 K355 H356 R357 A360 N363 N18 K19 T20 K66 H67 R68 A71 N74 3.6.4.- P03074 24109229 SDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPGL 4fb3 A 3.79 BS02 NUC W 1 S301 H302 A303 I304 Y305 S306 N307 K308 K381 S12 H13 A14 I15 Y16 S17 N18 K19 K92 3.6.4.- P03074 24109229 SDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPGL 4fb3 B 3.79 BS01 NUC C 1 S301 H302 I304 Y305 S306 N307 K308 T380 K381 S12 H13 I15 Y16 S17 N18 K19 T91 K92 3.6.4.- P03074 24109229 SDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPG 4fb3 E 3.79 BS01 NUC C 1 N307 T309 K355 H356 R357 A360 N363 N18 T20 K66 H67 R68 A71 N74 3.6.4.- P03074 24109229 SDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPG 4fb3 E 3.79 BS02 NUC W 1 S301 H302 A303 I304 Y305 S306 N307 K308 T380 S12 H13 A14 I15 Y16 S17 N18 K19 T91 3.6.4.- P03074 24109229 SDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPG 4gfv A 2.10 BS01 III F 1 Y62 K63 D64 V65 D197 R198 S229 S230 A231 G232 C233 G234 R235 Q276 Y57 K58 D59 V60 D192 R193 S222 S223 A224 G225 C226 G227 R228 Q269 3.1.3.48 Q99952 DSARSFLERLEARGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPPDHMLAMVEEARRLQGSGPEPLCVHSSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFC 4hew A 1.70 BS03 2MZ A 2 Q92 L198 T200 Q89 L194 T196 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS04 4MZ A 3 W5 N62 T200 P201 W2 N59 T196 P197 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS05 4MZ A 4 Q92 T200 P201 Q89 T196 P197 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS06 4MZ A 5 W5 G6 G63 W2 G3 G60 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS07 4MZ A 6 P138 P195 T208 P134 P191 T204 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS08 4MZ A 7 L57 D71 L54 D68 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS09 4MZ A 8 F70 D72 I91 F67 D69 I88 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hey A 1.45 BS10 4MZ A 9 E69 I91 E66 I88 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hez A 1.34 BS02 1MZ A 1 W5 N62 K170 W2 N59 K166 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hez A 1.34 BS03 1MZ A 2 V121 L198 T199 T200 V118 L194 T195 T196 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hez A 1.34 BS04 1MZ A 3 W5 N62 W2 N59 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hez A 1.34 BS06 1MZ A 5 Y51 D52 A54 D180 R182 Y48 D49 A51 D176 R178 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hez A 1.34 BS07 1MZ A 6 I91 D130 F131 G132 I88 D126 F127 G128 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hez A 1.34 BS08 1MZ A 7 D110 K111 K112 D107 K108 K109 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGAAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4hha A 1.60 BS01 III P 1 Y32 Y49 T56 R91 W94 P95 Y32 Y49 T56 R91 W94 P95 EVVLTQSPATLSLSPGERATISCRASQSVGGYLTWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISGLEPEDFAIYYCQQRGNWPPITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 4hha B 1.60 BS01 III P 1 H32 Y52A H56 H58 R94 G96 L97 S98 R99 D100 N100A S100B G100C F100D T100E L100G H32 Y53 H57 H59 R98 G100 L101 S102 R103 D104 N105 S106 G107 F108 T109 L111 QVQLVESGGGVVQPGRSLRLSCAASGFTFSNHGMHWVRQAPGKRLEWVAVISYDGRHEHYADLVKGRFTISRDNSKNTLYLQMNSLRAEDRALYFCAREGLSRDNSGFTGLIDYWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 4ho2 A 1.84 BS01 THM A 1 L6 G8 G9 Q80 P83 D84 G85 L86 D108 E194 L6 G8 G9 Q80 P83 D84 G85 L86 D108 E194 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho2 A 1.84 BS02 THM A 2 L43 Y112 G113 A249 E253 I254 R257 L43 Y112 G113 A249 E253 I254 R257 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho3 A 1.80 BS01 TTP A 1 L6 G8 G9 S10 G11 T12 R13 Q24 Q80 P83 D84 G85 L86 G107 D108 E194 L6 G8 G9 S10 G11 T12 R13 Q24 Q80 P83 D84 G85 L86 G107 D108 E194 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho3 A 1.80 BS02 TTP A 2 L43 Y112 G113 H114 G115 F116 T117 V248 A249 E253 I254 R257 L43 Y112 G113 H114 G115 F116 T117 V248 A249 E253 I254 R257 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho4 A 1.64 BS01 G1P A 1 L86 L106 N109 F143 G144 E159 K160 V170 W221 L86 L106 N109 F143 G144 E159 K160 V170 W221 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRS 4ho4 A 1.64 BS02 THM A 1 L6 G8 G9 Q24 Q80 P83 D84 G85 L86 G107 D108 L6 G8 G9 Q24 Q80 P83 D84 G85 L86 G107 D108 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRS 4ho4 B 1.64 BS01 THM B 1 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRSKDLVTVEG 4ho4 B 1.64 BS02 THM B 2 L43 Y112 G113 T117 V248 A249 E253 I254 R257 E296 G297 L43 Y112 G113 T117 V248 A249 E253 I254 R257 E296 G297 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRSKDLVTVEG 4ho5 A 1.70 BS01 DAU A 1 L6 G8 G9 Q24 Q80 P83 D84 G85 L86 L106 G107 D108 N109 F143 G144 E159 K160 V170 E194 W221 L6 G8 G9 Q24 Q80 P83 D84 G85 L86 L106 G107 D108 N109 F143 G144 E159 K160 V170 E194 W221 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho5 A 1.70 BS03 DAU B 1 G216 R217 G218 G216 R217 G218 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho5 B 1.70 BS02 DAU B 2 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 F143 G144 E159 K160 V170 E194 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 F143 G144 E159 K160 V170 E194 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRS 4ho8 A 2.60 BS01 UPG A 1 L6 G8 G9 K23 Q80 P83 D84 G85 L86 L106 D108 F143 G144 E159 K160 V170 R192 W221 L6 G8 G9 K23 Q80 P83 D84 G85 L86 L106 D108 F143 G144 E159 K160 V170 R192 W221 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho8 B 2.60 BS01 THM A 1 R217 G218 R217 G218 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho8 C 2.60 BS02 THM C 1 L43 Y112 G113 F116 V248 A249 E253 I254 R257 L43 Y112 G113 F116 V248 A249 E253 I254 R257 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho8 D 2.60 BS02 THM D 1 L43 Y112 G113 V248 A249 E253 I254 L43 Y112 G113 V248 A249 E253 I254 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4ho9 A 1.80 BS01 GDU A 1 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 N109 G144 E159 K160 V170 G172 Y174 R192 I197 W221 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 N109 G144 E159 K160 V170 G172 Y174 R192 I197 W221 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRSKDLVT 4ho9 A 1.80 BS02 UTP A 1 L43 Y112 G113 H114 G115 F116 T117 E118 V248 A249 I254 R257 L43 Y112 G113 H114 G115 F116 T117 E118 V248 A249 I254 R257 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHRSKDLVT 4ho9 B 1.80 BS02 GDU B 1 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 G144 E159 K160 V170 T171 Y174 R192 I197 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 G144 E159 K160 V170 T171 Y174 R192 I197 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSARGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4hoc A 2.20 BS01 UD1 A 1 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 N109 F143 G144 E159 K160 V170 G172 W221 L6 G8 G9 Q80 P83 D84 G85 L86 L106 D108 N109 F143 G144 E159 K160 V170 G172 W219 2.7.7.24 Q9AGY4 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPRFEQLLGGGSELGISLSYAVQSSPDGLAQAFIIGEEFIGDDNVALVLGDNIFYGHGFTELLQRAANRKSGATIFGYNVKDPQRFGVVEFDEKGKVISIEEKPEEPKSSYAVTGLYFYDNRVVDIAKNITPSGELEITDVNKAYLELGELHVELLGRGFAWLDTGTHESLLQASQFIETIEKRQSLKVACLEEIAYRMGYISREQLIKLAEPLMKNEYGQYLMNLAHR 4hwv A 1.37 BS01 CA A 1 D241 D292 D296 D227 D278 D282 23568384 MDIGINSDPNSAAPAGSIDSLGATGWASHGTPTTGGQGAAAERTYTVANRNELIQALYGNTAVIAPDGSVQGTPDKAPKVIRIRGTIDLNVDGQLRPYTPDRYVAGSCASSVHGYASQASLWSDYLAAYRPGAWGNARTVSGKPEDARACAAELQRRVVTISVPDNTSLLGIGTDAKILHGNLMLGTPDAPVANIVIRNITFEDAFDDFPQWDPTDSSDGRWNSEYDLISVAHASHVWIDHNTFSDGDRHDHAFPSVWHETVHGTDYSGGDFKVQHHDGLVDVTRHGNYVTLSNNHFHDHDKAFLIGGTDVPGADSGNPRMLKVTFHGNHFQNLRQRQARVRYGMVHLYNNYYENTRDASADYPWLAGMTLGQSGKVHAENNVVSLAGPDRPARPADVANARISAARTQDCAALFSASECASTFYDSGTVLNGGPADLTAAVRWSSALAAAPAWKPSDFYDYTLEDTADLAARITARAGAGKLEGPAEPRKLAAALEH 4i5x A 2.10 BS01 FLF A 1 W21 K22 Y49 H111 F123 V301 L302 W23 K24 Y51 H113 F125 V303 L304 1.1.1.- O60218 24100137 AHMATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFDAEY 4i5x A 2.10 BS02 NAP A 1 G19 T20 W21 D44 Y49 K78 H111 S160 N161 Q184 Y210 S211 P212 L213 G214 S215 P216 D217 L229 A246 I261 P262 K263 S264 V265 T266 R269 E272 N273 G21 T22 W23 D46 Y51 K80 H113 S162 N163 Q186 Y212 S213 P214 L215 G216 S217 P218 D219 L231 A248 I263 P264 K265 S266 V267 T268 R271 E274 N275 1.1.1.- O60218 24100137 AHMATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFDAEY 4icq A 2.25 BS01 ZN A 1 E319 Y355 H381 D383 E319 Y355 H381 D383 3.4.11.- Q97SP8 23999297 MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNWAN 4icq A 2.25 BS02 ZN A 2 E253 E319 H348 E253 E319 H348 3.4.11.- Q97SP8 23999297 MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNWAN 4icq B 2.25 BS01 ZN B 1 E319 H381 D383 E319 H381 D383 3.4.11.- Q97SP8 23999297 MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNWAN 4icr B 2.17 BS02 ZN B 2 E253 E319 H348 D383 E248 E314 H343 D378 3.4.11.- Q97SP8 23999297 FKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDDNASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNW 4ics A 1.97 BS03 TRP A 1 W144 S234 A235 P247 N248 T251 E253 F255 E319 Y355 H381 W144 S234 A235 P247 N248 T251 E253 F255 E319 Y355 H381 3.4.11.- Q97SP8 23999297 MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDDNASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNWAN 4ics A 1.97 BS04 GLY A 1 N248 D383 N248 D383 3.4.11.- Q97SP8 23999297 MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDDNASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNWAN 4ics B 1.97 BS04 GLY B 1 V146 N248 D383 V146 N248 D383 3.4.11.- Q97SP8 23999297 MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDDNASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDGTRVPLFRNGNWAN 4if6 A 2.25 BS01 III B 1 K236 N241 T242 I243 R276 R466 P468 F474 D475 V476 E477 L478 L479 G480 D481 V484 I485 K4 N9 T10 I11 R44 R234 P236 F242 D243 V244 E245 L246 L247 G248 D249 V252 I253 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEI 4if6 A 2.25 BS03 APR A 1 G261 A262 G263 V266 D272 F273 R274 Y280 Q345 H363 F414 G440 S441 S442 V445 N465 R466 E467 G480 D481 C482 G29 A30 G31 V34 D40 F41 R42 Y48 Q113 H131 F182 G208 S209 S210 V213 N233 R234 E235 G248 D249 C250 3.5.1.- Q96EB6 24120939 MRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEI 4is6 A 2.50 BS01 III C 1 Q9 E11 W43 A52 S53 F54 G58 N62 V65 D66 N69 I72 M73 K75 Q7 E9 W41 A50 S51 F52 G56 N60 V63 D64 N67 I70 M71 K73 P01903 24108701 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4is6 B 2.50 BS01 III C 1 V11 H13 Y30 Y37 D57 Y60 W61 L67 K71 Y78 H81 N82 V85 V10 H12 Y29 Y36 D56 Y59 W60 L66 K70 Y77 H80 N81 V84 P13760 24108701 DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWR 4jd6 A 3.50 BS01 COA A 1 F24 V85 V87 H91 R92 R93 G95 L96 L97 R98 S121 E122 I125 Y126 R128 F22 V79 V81 H85 R86 R87 G89 L90 L91 R92 S115 E116 I119 Y120 R122 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jd6 A 3.50 BS02 TOY A 1 F24 D26 I28 W36 S83 F84 V85 H119 Y126 E203 E401 F402 F22 D24 I26 W34 S77 F78 V79 H113 Y120 E197 E395 F396 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jd6 A 3.50 BS03 COA C 1 D260 S261 D254 S255 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jd6 B 3.50 BS02 COA B 1 S23 F24 V85 V87 R92 R93 R94 G95 L96 L97 R98 S121 E122 I125 Y126 R128 S21 F22 V79 V81 R86 R87 R88 G89 L90 L91 R92 S115 E116 I119 Y120 R122 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jd6 C 3.50 BS02 COA C 1 V85 V87 R92 R93 G95 L96 L97 R98 H119 A120 S121 I125 Y126 R128 V79 V81 R86 R87 G89 L90 L91 R92 H113 A114 S115 I119 Y120 R122 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jd6 E 3.50 BS01 COA E 1 V85 A86 V87 R93 G95 L97 R98 H119 S121 E122 I125 Y126 R128 V79 A80 V81 R87 G89 L91 R92 H113 S115 E116 I119 Y120 R122 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jd6 F 3.50 BS02 COA F 1 V85 V87 R92 R93 R94 G95 L96 L97 R98 H119 S121 E122 I125 Y126 R128 V79 V81 R86 R87 R88 G89 L90 L91 R92 H113 S115 E116 I119 Y120 R122 I6X469 24106131 VTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAEAKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF 4jih A 2.30 BS01 EPR A 1 W21 Y49 W80 H111 F123 C299 V301 L302 W23 Y51 W82 H113 F125 C301 V303 L304 1.1.1.- O60218 24100137 SHMATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFDAEY 4jii X 2.20 BS02 ZST X 1 W21 Y49 W80 H111 W112 Q114 F116 F123 W220 C299 V301 L302 S304 Y310 P311 W23 Y51 W82 H113 W114 Q116 F118 F125 W222 C301 V303 L304 S306 Y312 P313 1.1.1.- O60218 24100137 SHMATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFDAEY 4jir A 2.00 BS01 EPR A 1 W20 V47 Y48 H110 W111 F122 C298 W21 V48 Y49 H111 W112 F123 C299 1.1.1.21 P15121 24100137 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF 4jir A 2.00 BS02 NAP A 1 G18 T19 W20 K21 D43 Y48 H110 S159 N160 Q183 Y209 S210 P211 L212 G213 S214 P215 D216 A245 I260 P261 K262 S263 V264 T265 R268 E271 N272 C298 G19 T20 W21 K22 D44 Y49 H111 S160 N161 Q184 Y210 S211 P212 L213 G214 S215 P216 D217 A246 I261 P262 K263 S264 V265 T266 R269 E272 N273 C299 1.1.1.21 P15121 24100137 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF 4jmo A 1.80 BS01 JAF A 1 L148 F151 R152 L153 I193 F243 K244 I245 P246 L95 F98 R99 L100 I140 F190 K191 I192 P193 Q99418 24112024 HMSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIP 4jmx A 2.55 BS01 IM2 A 1 M175 Y190 L192 G204 H208 W212 S223 H224 G225 C226 N228 M141 Y156 L158 G170 H174 W178 S189 H190 G191 C192 N194 L0T5Q5 23999293 PIPGVASVSPANGAVVGVAHPVVVTFTTPVTDRRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNGEVLRTMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV 4jrn A 2.71 BS01 ANP A 1 G259 G261 G262 F263 A264 V266 K281 M323 M356 M357 A359 D362 D427 G66 G68 G69 F70 A71 V73 K88 M130 M163 M164 A166 D169 D234 Q2PAY2 SELVFEKADSGCVIGKRILAHMQELENSERLDRILTVAAWPPDVPKRFVSVTTGETRTLVRGAPLGSGGFATVYEATDVETNEELAVKVFMSEKEPTDETMLDLQRESSCYRNFSLAKTAKDAQESCRFMVPSDVVMLEGQPASTEVVIGLTTRWVPNYFLLMMRAEADMSKVISWVFGDASVNKSEFGLVVRMYLSSQAIKLVANVQAQGIVHTDIKPANFLLLKDGRLFLGDFGTYRINNSVGRGTPGYEPPERPGITYTFPTDAWQLGITLYCIWCKERPTPADGIWDYLHFADCPSTPELVQDLIRSLLNRDPQKRMLPLQALETAAFKEMDSVVKGAAQNFEQQ 4jrn A 2.71 BS02 MG A 1 K411 A413 N414 K218 A220 N221 Q2PAY2 SELVFEKADSGCVIGKRILAHMQELENSERLDRILTVAAWPPDVPKRFVSVTTGETRTLVRGAPLGSGGFATVYEATDVETNEELAVKVFMSEKEPTDETMLDLQRESSCYRNFSLAKTAKDAQESCRFMVPSDVVMLEGQPASTEVVIGLTTRWVPNYFLLMMRAEADMSKVISWVFGDASVNKSEFGLVVRMYLSSQAIKLVANVQAQGIVHTDIKPANFLLLKDGRLFLGDFGTYRINNSVGRGTPGYEPPERPGITYTFPTDAWQLGITLYCIWCKERPTPADGIWDYLHFADCPSTPELVQDLIRSLLNRDPQKRMLPLQALETAAFKEMDSVVKGAAQNFEQQ 4jrn A 2.71 BS03 SUC A 1 N220 L224 S260 G261 G262 A264 T265 M284 S285 E286 R347 N27 L31 S67 G68 G69 A71 T72 M91 S92 E93 R154 Q2PAY2 SELVFEKADSGCVIGKRILAHMQELENSERLDRILTVAAWPPDVPKRFVSVTTGETRTLVRGAPLGSGGFATVYEATDVETNEELAVKVFMSEKEPTDETMLDLQRESSCYRNFSLAKTAKDAQESCRFMVPSDVVMLEGQPASTEVVIGLTTRWVPNYFLLMMRAEADMSKVISWVFGDASVNKSEFGLVVRMYLSSQAIKLVANVQAQGIVHTDIKPANFLLLKDGRLFLGDFGTYRINNSVGRGTPGYEPPERPGITYTFPTDAWQLGITLYCIWCKERPTPADGIWDYLHFADCPSTPELVQDLIRSLLNRDPQKRMLPLQALETAAFKEMDSVVKGAAQNFEQQ 4jwl A 1.95 BS01 HRC A 1 L148 F151 R152 L153 I193 F243 I245 P246 L95 F98 R99 L100 I140 F190 I192 P193 Q99418 24112024 HMSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPE 4jxh A 1.47 BS01 HRC A 1 L148 R152 L153 P154 I160 M164 I193 I245 L94 R98 L99 P100 I106 M110 I139 I191 Q99418 24112024 MSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDD 4k3x E 2.15 BS01 FUC E 1 T263A N264 T258 N259 DQICIGYHSNNSTQTVNTLLESNVPVTSSHSILEKEHNGLLCKLKGKAPLDLIDCSLPAWLMGNPKCDELLTASEWAYIKEDPEPENGICFPGDFDSLEDLILLVSNTDHFRKEKIIDMTRFSDVTTNNVDSACPYDTNGASFYRNLNWVQQNKGKQLIFHYQNSENNPLLIIWGVHQTSNAAEQNTYYGSQTGSTTITIGEETNTYPLVISESSILNGHSDRINYFWGVVNPNQNFSIVSTGNFIWPEYGYFFQKTTNISGIIKSSEKISDCDTICQTKIGAINSTLPFQNIHQNAIGDCPKYVKAQELVLATGLRNNPIK 4k3x B 2.15 BS01 FUL A 1 Q62 F63 Q57 F58 IAGFIEGGWQGLIDGWYGYHHQNSEGSGYAADKEATQKAVDAITTKVNNIIDKMNTQFESTAKEFNKIEMRIKHLSDRVDDGFLDVWSYNAELLVLLENERTLDFHDANVNNLYQKVKVQLKDNAIDMGNGCFKILHKCNNTCMDDIKNGTYNYYEYRKESHLEKQKIDS 4k3y A 2.68 BS01 CA A 1 N293 D297 A298 D324 G345 E346 G347 G348 N197 D201 A202 D227 G245 E246 G247 G248 ATPLVLGENLCSINGWVPTYRGEGTTGKIPDEQMLTRQNFVSCSDKECRRFFVSMGYVSEQMNVYSVKLGDPPTPDKLKFEAVGWSASSCHDGFQWTVLSVAGDGFVSILYGGIITDTIHPTNGGPLRTQASSCICNDGTCYTIIADGTTYTASSHRLYRLVNGTSAGWKALDTTGFNFEFPTCYYTSGKVKCTGTNLWNDAKRPFLEFDQSFTYTFKEPCLGFLGDTPRGIDTTNYCDKTTTEGEGGIQGFMIEGSNSWIGRIINPGSKKGFEIYKFLGTLFSVQTVGNRNYQLLSNSTIGRSGLYQPAYESRDCQELCFWIEIAATTKAGLSSNDLITFCGTGGSMPDVNWG 4k3y B 2.68 BS01 CA B 1 N293 D297 A298 D324 E344 G345 E346 G347 G348 N197 D201 A202 D227 E244 G245 E246 G247 G248 ATPLVLGENLCSINGWVPTYRGEGTTGKIPDEQMLTRQNFVSCSDKECRRFFVSMGYVSEQMNVYSVKLGDPPTPDKLKFEAVGWSASSCHDGFQWTVLSVAGDGFVSILYGGIITDTIHPTNGGPLRTQASSCICNDGTCYTIIADGTTYTASSHRLYRLVNGTSAGWKALDTTGFNFEFPTCYYTSGKVKCTGTNLWNDAKRPFLEFDQSFTYTFKEPCLGFLGDTPRGIDTTNYCDKTTTEGEGGIQGFMIEGSNSWIGRIINPGSKKGFEIYKFLGTLFSVQTVGNRNYQLLSNSTIGRSGLYQPAYESRDCQELCFWIEIAATTKAGLSSNDLITFCGTGGSMPDVNWG 4k3y D 2.68 BS01 CA D 1 N293 L294 D297 A298 D324 G345 G347 G348 N197 L198 D201 A202 D227 G245 G247 G248 ATPLVLGENLCSINGWVPTYRGEGTTGKIPDEQMLTRQNFVSCSDKECRRFFVSMGYVSEQMNVYSVKLGDPPTPDKLKFEAVGWSASSCHDGFQWTVLSVAGDGFVSILYGGIITDTIHPTNGGPLRTQASSCICNDGTCYTIIADGTTYTASSHRLYRLVNGTSAGWKALDTTGFNFEFPTCYYTSGKVKCTGTNLWNDAKRPFLEFDQSFTYTFKEPCLGFLGDTPRGIDTTNYCDKTTTEGEGGIQGFMIEGSNSWIGRIINPGSKKGFEIYKFLGTLFSVQTVGNRNYQLLSNSTIGRSGLYQPAYESRDCQELCFWIEIAATTKAGLSSNDLITFCGTGGSMPDVNWG 4k90 A 1.80 BS01 ZN A 1 H429 H433 E459 H184 H188 E214 3.4.24.- P46075 24100314 ADYQVYAWGINDPTEGERTVIKDPWDSVASEFTWISDGSTNYTTSRGNNGIAQSNPSGGPSYLNNYRPSSSSLSFKYPYSVSSSPPSSYIDASIIQLFYTANIYHDLLYTLGFTEKAGNFEYNTNGQGGLGNDYVILNAQDGSGTNNANFATPPDGQPGRMRMYVWTESTPYRDGSFEAGIVIHEYTHGLSNRLTGGPANSNCLNALESGGMGEGWSDFMATAIRLKPGDKRSTDYTMGEWASNRAGGIRQYPYSTSLSTNPLTYTSVNSLNAVHAIGTVWASMLYEVLWNLIDKHGKNDAPKPTLRDGVPTDGKYLAMKLVMDGMALQPCNPNFVQARDAILDADTALTGGENQCEIWTAFAKRGLGAGAKYSSRNRVGSTEVPSGVC 4k90 A 1.80 BS02 CA A 1 N364 L375 D378 D400 N119 L130 D133 D155 3.4.24.- P46075 24100314 ADYQVYAWGINDPTEGERTVIKDPWDSVASEFTWISDGSTNYTTSRGNNGIAQSNPSGGPSYLNNYRPSSSSLSFKYPYSVSSSPPSSYIDASIIQLFYTANIYHDLLYTLGFTEKAGNFEYNTNGQGGLGNDYVILNAQDGSGTNNANFATPPDGQPGRMRMYVWTESTPYRDGSFEAGIVIHEYTHGLSNRLTGGPANSNCLNALESGGMGEGWSDFMATAIRLKPGDKRSTDYTMGEWASNRAGGIRQYPYSTSLSTNPLTYTSVNSLNAVHAIGTVWASMLYEVLWNLIDKHGKNDAPKPTLRDGVPTDGKYLAMKLVMDGMALQPCNPNFVQARDAILDADTALTGGENQCEIWTAFAKRGLGAGAKYSSRNRVGSTEVPSGVC 4k90 A 1.80 BS03 CA A 2 N437 R438 T440 G441 G442 N445 N192 R193 T195 G196 G197 N200 3.4.24.- P46075 24100314 ADYQVYAWGINDPTEGERTVIKDPWDSVASEFTWISDGSTNYTTSRGNNGIAQSNPSGGPSYLNNYRPSSSSLSFKYPYSVSSSPPSSYIDASIIQLFYTANIYHDLLYTLGFTEKAGNFEYNTNGQGGLGNDYVILNAQDGSGTNNANFATPPDGQPGRMRMYVWTESTPYRDGSFEAGIVIHEYTHGLSNRLTGGPANSNCLNALESGGMGEGWSDFMATAIRLKPGDKRSTDYTMGEWASNRAGGIRQYPYSTSLSTNPLTYTSVNSLNAVHAIGTVWASMLYEVLWNLIDKHGKNDAPKPTLRDGVPTDGKYLAMKLVMDGMALQPCNPNFVQARDAILDADTALTGGENQCEIWTAFAKRGLGAGAKYSSRNRVGSTEVPSGVC 4khz E 2.90 BS04 GLC E 4 E44 Y341 R344 E44 Y341 R344 P0AEX9 KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 4khz F 2.90 BS01 GLC F 1 Y325 Y383 S433 F436 Y303 Y361 S411 F414 P02916 SVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSITADEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVN 4khz F 2.90 BS02 GLC F 2 Y325 S329 N376 L379 G380 F436 N437 N440 Y303 S307 N354 L357 G358 F414 N415 N418 P02916 SVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSITADEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVN 4ki0 A 2.38 BS02 ANP A 1 W13 V18 S38 G39 C40 G41 K42 S43 T44 Q82 E159 H192 W12 V17 S37 G38 C39 G40 K41 S42 T43 Q81 E158 H191 C9QV42 ASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQVGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDVVLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGVA 4ki0 F 2.38 BS01 GLC F 1 A432 F436 A417 F421 P02916 SDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSINWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVN 4ki0 F 2.38 BS02 GLC F 2 Y325 Y383 S433 Y310 Y368 S418 P02916 SDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSINWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVN 4ki0 F 2.38 BS03 GLC F 3 T291 N376 L379 G380 N437 N440 T276 N361 L364 G365 N422 N425 P02916 SDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSINWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVN 4kwl A 1.63 BS02 3SS A 1 Y58 R60 L75 W77 H86 H88 C93 H140 V142 H155 Y157 Y55 R57 L72 W74 H83 H85 C90 H137 V139 H152 Y154 1.13.11.20 P21816 24084026 TELLKPRTLADLIRILHELFAGDEVNVEEVQAVLEAYESNPAEWALYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTDSHCFLKLLQGNLKETLFDWPDKKSNEMIKKSERTLRENQCAYINDSIGLHRVENVSHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTP 4l62 A 2.90 BS01 NUC Q 1 V28 G29 L30 K41 Y45 S50 K51 V25 G26 L27 K38 Y42 S47 K48 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 A 2.90 BS02 NUC R 1 Y5 P40 G42 S43 H46 Y2 P37 G39 S40 H43 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 B 2.90 BS01 NUC Q 1 T8 P40 K41 G42 S43 H46 Y47 T2 P34 K35 G36 S37 H40 Y41 Q9I1S1 24070609 DTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 C 2.90 BS01 NUC Q 1 P40 G42 S43 H46 P37 G39 S40 H43 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 C 2.90 BS02 NUC R 1 V28 G29 L30 Y45 S50 K51 V25 G26 L27 Y42 S47 K48 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 D 2.90 BS02 NUC R 1 T8 P40 G42 S43 H46 Y47 T2 P34 G36 S37 H40 Y41 Q9I1S1 24070609 DTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 H 2.90 BS01 NUC S 1 P40 G42 S43 Y47 P37 G39 S40 Y44 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 H 2.90 BS02 NUC T 1 V28 G29 L30 Y45 K51 V25 G26 L27 Y42 K48 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 I 2.90 BS02 NUC V 1 Y5 G42 S43 H46 Y2 G39 S40 H43 Q9I1S1 24070609 SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l62 P 2.90 BS01 NUC W 1 G29 L30 K41 Y45 S50 K51 G23 L24 K35 Y39 S44 K45 Q9I1S1 24070609 DTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACPPCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRSLLE 4l73 A 2.50 BS01 CA A 1 S124 D184 E210 E212 S10 D70 E96 E98 O27564 SRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAERYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISALV 4l76 A 2.99 BS01 CA A 1 S124 D184 E210 Q212 S12 D72 E98 Q100 O27564 AKSRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAQRYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISALVP 4l76 D 2.99 BS02 CA D 2 D184 E210 Q212 D69 E95 Q97 O27564 RHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAQRYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISAL 4l76 D 2.99 BS03 CA D 3 R241 D245 Y247 E248 R126 D130 Y132 E133 O27564 RHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAQRYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISAL 4lis A 2.80 BS01 UPG A 1 K88 V90 S128 A129 Y156 F198 N199 N219 L220 L223 L235 L236 V237 F238 A249 R251 Y253 R313 D316 K87 V89 S127 A128 Y155 F197 N198 N218 L219 L222 L234 L235 V236 F237 A248 R250 Y252 R312 D315 C8VAU8 24116166 PSGSVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTELGWKAQRTLEQACEDLWLWTKNNPQGYRQQPPAEL 4lis A 2.80 BS02 NAD A 1 G10 G13 Y14 I15 D34 N35 Y37 N38 S39 L60 D61 V62 F84 A85 A86 K88 V103 S128 Y156 K160 Y197 F198 P200 G9 G12 Y13 I14 D33 N34 Y36 N37 S38 L59 D60 V61 F83 A84 A85 K87 V102 S127 Y155 K159 Y196 F197 P199 C8VAU8 24116166 PSGSVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTELGWKAQRTLEQACEDLWLWTKNNPQGYRQQPPAEL 4lis B 2.80 BS01 UDP B 1 N199 N219 L220 L223 L236 V237 F238 A249 R251 V290 R313 D316 N197 N217 L218 L221 L234 V235 F236 A247 R249 V288 R311 D314 C8VAU8 24116166 SGSVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTELGWKAQRTLEQACEDLWLWTKNNPQGYRQQPPAEL 4lis C 2.80 BS01 UDP C 1 N199 Y218 N219 L220 L223 L235 L236 V237 F238 R251 V290 R313 D316 N198 Y217 N218 L219 L222 L234 L235 V236 F237 R250 V289 R312 D315 C8VAU8 24116166 PSGSVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTELGWKAQRTLEQACEDLWLWTKNNPQGYRQQPPAEL 4lis C 2.80 BS02 NAD C 1 G13 Y14 I15 D34 N35 Y37 N38 S39 L60 D61 V62 F84 A85 A86 K88 V103 S126 S127 S128 Y156 K160 Y197 P200 G12 Y13 I14 D33 N34 Y36 N37 S38 L59 D60 V61 F83 A84 A85 K87 V102 S125 S126 S127 Y155 K159 Y196 P199 C8VAU8 24116166 PSGSVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIELAITDVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTELGWKAQRTLEQACEDLWLWTKNNPQGYRQQPPAEL 4lp6 A 2.15 BS01 Q4I A 1 H94 H96 H119 V121 F130 V134 V142 L197 T198 T199 P201 W208 H91 H93 H116 V118 F127 V131 V139 L194 T195 T196 P198 W205 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4lp6 A 2.15 BS03 ZN A 2 K171 E233 K168 E230 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4lp6 A 2.15 BS05 Q4I B 1 H4 W5 D19 F20 H64 P201 H1 W2 D16 F17 H61 P198 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4lp6 B 2.15 BS01 Q4I A 1 H4 W5 F20 H64 P201 H1 W2 F17 H61 P198 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 4lse A 2.10 BS01 BR A 1 M38 Q66 N68 M38 Q66 N68 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lse A 2.10 BS02 BR A 2 L20 M38 T39 Y40 L20 M38 T39 Y40 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lse A 2.10 BS03 MG A 1 N207 N236 N252 N207 N236 N252 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lse A 2.10 BS04 BR B 1 D126 R168 D126 R168 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lse B 2.10 BS01 BR B 2 Y14 G15 K16 R42 Y14 G15 K16 R42 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lse C 2.10 BS01 BR B 3 K16 A17 A41 R42 K16 A17 A41 R42 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lse C 2.10 BS03 MG C 2 D126 R168 N170 D126 R168 N170 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsf A 1.90 BS01 BR A 1 Y124 S125 R167 Y123 S124 R166 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsf B 1.90 BS02 BR B 2 N306 M307 S308 V337 Q339 N305 M306 S307 V336 Q338 P02931 24106986 AEIYNKDGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsh A 2.20 BS01 BR A 1 R100 D126 V133 G134 R163 R95 D121 V128 G129 R158 P02931 24106986 AEIGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsh A 2.20 BS03 BR A 3 N69 S70 A75 N64 S65 A70 P02931 24106986 AEIGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsh A 2.20 BS04 BR A 4 K89 R140 N141 S142 K84 R135 N136 S137 P02931 24106986 AEIGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsh B 2.20 BS01 BR B 1 M114 Q262 R270 M108 Q256 R264 P02931 24106986 AEGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsh B 2.20 BS02 BR B 2 S125 R167 R168 S119 R161 R162 P02931 24106986 AEGNKVDLYGKAVGLHYFSKGGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsi A 2.09 BS04 BR A 2 Y102 G103 V104 Y106 F129 V130 G131 Y96 G97 V98 Y100 F123 V124 G125 P02931 24106986 DGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsi A 2.09 BS05 BR A 3 M114 L115 P116 Q262 S272 M108 L109 P110 Q256 S266 P02931 24106986 DGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4lsi C 2.09 BS02 MG C 2 N69 D74 N63 D68 P02931 24106986 DGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF 4luw A 2.25 BS01 HEM A 1 W180 A183 R185 C186 V187 G188 L195 S228 F355 S356 W358 E363 W449 F475 Y477 W103 A106 R108 C109 V110 G111 L118 S151 F278 S279 W281 E286 W372 F398 Y400 1.14.13.39 P29473 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4luw A 2.25 BS03 QJ8 A 1 P336 V338 N340 F355 W358 Y359 E363 Y477 P259 V261 N263 F278 W281 Y282 E286 Y400 1.14.13.39 P29473 GPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4luw B 2.25 BS03 HEM B 1 W180 R185 C186 V187 G188 S228 F355 S356 G357 W358 M360 E363 W449 F475 Y477 W102 R107 C108 V109 G110 S150 F277 S278 G279 W280 M282 E285 W371 F397 Y399 1.14.13.39 P29473 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4luw B 2.25 BS05 QJ8 B 1 V106 L107 P336 V338 F355 W358 Y359 E363 V38 L39 P258 V260 F277 W280 Y281 E285 1.14.13.39 P29473 KFPRVKNWELGSITYDTLCAQSQQDGPCTPRRCLGSLVLPRKPAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEAPELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPDPW 4lux A 1.86 BS01 HEM A 1 W409 A412 R414 C415 V416 S457 M570 F584 S585 G586 W587 M589 E592 W678 F704 W100 A103 R105 C106 V107 S148 M261 F275 S276 G277 W278 M280 E283 W369 F395 1.14.13.39 P29476 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4lux A 1.86 BS03 QJ8 A 1 L337 R414 P565 V567 F584 W587 Y588 E592 W678 Y706 L39 R105 P256 V258 F275 W278 Y279 E283 W369 Y397 1.14.13.39 P29476 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW 4lux B 1.86 BS03 HEM B 1 W409 A412 C415 V416 S457 F584 S585 G586 W587 M589 E592 W678 F704 W102 A105 C108 V109 S150 F277 S278 G279 W280 M282 E285 W371 F397 1.14.13.39 P29476 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4lux B 1.86 BS05 QJ8 B 1 M336 L337 R414 Q478 P565 V567 F584 W587 E592 Y706 M38 L39 R107 Q171 P258 V260 F277 W280 E285 Y399 1.14.13.39 P29476 RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKG 4lwa A 2.06 BS01 HEM A 1 W60 R65 C66 I67 F235 N236 G237 W238 M240 E243 V300 W329 Y355 Y357 W59 R64 C65 I66 F234 N235 G236 W237 M239 E242 V299 W328 Y354 Y356 1.14.13.165 O34453 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4lwa A 2.06 BS02 Q13 A 1 I218 F235 N236 G237 W238 Y239 E243 R247 W329 I217 F234 N235 G236 W237 Y238 E242 R246 W328 1.14.13.165 O34453 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4lwb A 2.15 BS01 HEM A 1 W60 R65 C66 M221 F235 N236 G237 W238 M240 E243 W329 Y355 Y357 W59 R64 C65 M220 F234 N235 G236 W237 M239 E242 W328 Y354 Y356 1.14.13.165 O34453 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4lwb A 2.15 BS02 QJ8 A 1 H128 I218 D220 F235 G237 W238 Y239 E243 W329 Y357 H127 I217 D219 F234 G236 W237 Y238 E242 W328 Y356 1.14.13.165 O34453 EEKEILWNEAKAFIAACYQELGKAAEVKDRLADIKSEIDLTGSYVHTKEELEHGAKMAWRNSNRCIGRLFWNSLNVIDRRDVRTKEEVRDALFHHIETATNNGKIRPTITIFPPEEKGEKQVEIWNHQLIRYAGYESDGERIGDPASCSLTAACEELGWRGERTDFDLLPLIFRMKGDEQPVWYELPRSLVIEVPITHPDIEAFSDLELKWYGVPIISDMKLEVGGIHYNAAPFNGWYMGTEIGARNLADEKRYDKLKKVASVIGIAADYNTDLWKDQALVELNKAVLHSYKKQGVSIVDHHTAASQFKRFEEQAEEAGRKLTGDWTWLIPPISPAATHIFHRSYDNSIVKPNYFYQDKPYE 4m63 C 2.75 BS01 ATP C 1 G13 S14 G15 M16 K18 G156 D157 V159 G182 R183 R210 K213 E214 G301 G302 M305 Y306 K336 G8 S9 G10 M11 K13 G145 D146 V148 G171 R172 R199 K202 E203 G290 G291 M294 Y295 K323 3.6.1.3 P10987 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCAAAIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 4m63 D 2.75 BS01 ATP D 1 G13 S14 G15 M16 K18 G156 D157 G158 V159 G182 R210 K213 E214 G301 G302 M305 Y306 K336 G9 S10 G11 M12 K14 G143 D144 G145 V146 G169 R197 K200 E201 G288 G289 M292 Y293 K323 3.6.1.3 P10987 VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCAAAIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 4m63 D 2.75 BS02 CA D 1 D11 K18 Q137 D7 K14 Q124 3.6.1.3 P10987 VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCAAAIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 4m63 E 2.75 BS02 CA E 1 D11 G13 Q137 D6 G8 Q113 3.6.1.3 P10987 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPGDEAQSKRGILYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCAAAIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC 4m9s A 3.21 BS01 III E 1 Q379 V382 E383 R390 S391 A394 V467 D469 Q379 V382 E383 R390 S391 A394 V461 D463 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s A 3.21 BS02 MG A 1 S166 D250 T271 S166 D250 T271 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s A 3.21 BS03 ATP A 1 M128 Y131 A161 G162 G164 K165 S166 V167 R273 F301 Y305 P330 A331 M334 P368 Y369 M128 Y131 A161 G162 G164 K165 S166 V167 R273 F301 Y305 P330 A331 M334 P368 Y369 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s B 3.21 BS02 MG B 1 S166 D250 S166 D250 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s C 3.21 BS01 III G 1 Q379 V382 E383 R390 S391 A394 V467 V468 D469 Q379 V382 E383 R390 S391 A394 V461 V462 D463 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s C 3.21 BS02 MG C 1 S166 K191 S166 K191 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s D 3.21 BS01 III H 1 E383 R390 A394 V467 V468 D469 T472 E383 R390 A394 V458 V459 D460 T463 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s D 3.21 BS02 MG D 1 S166 D250 D251 S166 D250 D251 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9s D 3.21 BS03 ATP D 1 M128 Y131 G162 G164 K165 S166 V167 Q171 R273 F301 P330 A331 M334 T367 P368 Y369 M128 Y131 G162 G164 K165 S166 V167 Q171 R273 F301 P330 A331 M334 T367 P368 Y369 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9x A 3.34 BS01 III C 1 Q379 V382 E383 R390 A394 V467 V468 D469 Q379 V382 E383 R390 A394 V461 V462 D463 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9x B 3.34 BS01 III D 1 Q379 V382 E383 R390 A394 V467 T472 Q379 V382 E383 R390 A394 V458 T463 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9y A 4.20 BS02 MG A 1 S166 K191 D250 D251 S166 K191 D250 D251 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9y B 4.20 BS01 III D 1 Q379 V382 E383 R390 A394 V467 Q379 V382 E383 R390 A394 V458 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9z A 3.40 BS02 MG A 1 S166 D250 D251 T271 S166 D250 D251 T271 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9z D 3.40 BS01 III H 1 Q379 E383 R390 A394 V467 V468 D469 T472 Q379 E383 R390 A394 V458 V459 D460 T463 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4m9z D 3.40 BS02 MG D 1 K165 S166 D250 T271 K165 S166 D250 T271 P30429 24065769 MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNETVIRPEDFPKFMQLHQKFYDSLKNFACC 4mc5 A 2.24 BS01 FUC A 1 N263 Q391 F392 N260 Q380 F381 GDQICIGYHSNNSTQTVNTLLESNVPVTSSHSILEKEHNGLLCKLKGKAPLDLIDCSLPAWLMGNPKCDELLTASEWAYIKEDPEPENGICFPGDFDSLEDLILLVSNTDHFRKEKIIDMTRFSDVTTNNVDSACPYDTNGASFYRNLNWVQQNKGKQLIFHYQNSENNPLLIIWGVHQTSNAAEQNTYYGSQTGSTTITIGEETNTYPLVISESSILNGHSDRINYFWGVVNPNQNFSIVSTGNFIWPEYGYFFQKTTNISGIIKSSEKISDCDTICQTKIGAINSTLPFQNIHQNAIGDCPKYVKAQELVLATGLRNNPIAIAGFIEGGWQGLIDGWYGYHHQNSEGSGYAADKEATQKAVDAITTKVNNIIDKMNTQFESTAKEFNKIEMRIKHLSDRVDDGFLDVWSYNAELLVLLENERTLDFHDANVNNLYQKVKVQLKDNAIDMGNGCFKILHKCNNTCMDDIKNGTYNYYEYRKESHLEKQKIDSG 4mc5 B 2.24 BS01 FUC B 1 T262 N263 Q391 F392 T259 N260 Q380 F381 GDQICIGYHSNNSTQTVNTLLESNVPVTSSHSILEKEHNGLLCKLKGKAPLDLIDCSLPAWLMGNPKCDELLTASEWAYIKEDPEPENGICFPGDFDSLEDLILLVSNTDHFRKEKIIDMTRFSDVTTNNVDSACPYDTNGASFYRNLNWVQQNKGKQLIFHYQNSENNPLLIIWGVHQTSNAAEQNTYYGSQTGSTTITIGEETNTYPLVISESSILNGHSDRINYFWGVVNPNQNFSIVSTGNFIWPEYGYFFQKTTNISGIIKSSEKISDCDTICQTKIGAINSTLPFQNIHQNAIGDCPKYVKAQELVLATGLRNNPIAIAGFIEGGWQGLIDGWYGYHHQNSEGSGYAADKEATQKAVDAITTKVNNIIDKMNTQFESTAKEFNKIEMRIKHLSDRVDDGFLDVWSYNAELLVLLENERTLDFHDANVNNLYQKVKVQLKDNAIDMGNGCFKILHKCNNTCMDDIKNGTYNYYEYRKESHLEKQKIDSG 4mc7 A 2.99 BS01 CA A 1 N281 D285 D311 G329 E330 G331 G332 N207 D211 D237 G255 E256 G257 G258 ATPLVLGENLCSINGWVPTYRGEGTTGKIPDEQMLTRQNFVSCSDKECRRFFVSMGYGTTTNFADLIVSEQMNVYSVKLGDPPTPDKLKFEAVGWSASSCHDGFQWTVLSVAGDGFVSILYGGIITDTIHPTNGGPLRTQASSCICNDGTCYTIIADGTTYTASSHRLYRLVNGTSAGWKALDTTGFNFEFPTCYYTSGKVKCTGTNLWNDAKRPFLEFDQSFTYTFKEPCLGFLGDTPRGIDTTNYCDKTTTEGEGGIQGFMIEGSNSWIGRIINPGSKKGFEIYKFLGTLFSVQTVGNRNYQLLSNSTIGRSGLYQPAYESRDCQELCFWIEIAATTKAGLSSNDLITFCGTGGSMPDVNW 4mc7 C 2.99 BS01 CA C 1 N281 L282 D285 D311 G329 G331 N207 L208 D211 D237 G255 G257 ATPLVLGENLCSINGWVPTYRGEGTTGKIPDEQMLTRQNFVSCSDKECRRFFVSMGYGTTTNFADLIVSEQMNVYSVKLGDPPTPDKLKFEAVGWSASSCHDGFQWTVLSVAGDGFVSILYGGIITDTIHPTNGGPLRTQASSCICNDGTCYTIIADGTTYTASSHRLYRLVNGTSAGWKALDTTGFNFEFPTCYYTSGKVKCTGTNLWNDAKRPFLEFDQSFTYTFKEPCLGFLGDTPRGIDTTNYCDKTTTEGEGGIQGFMIEGSNSWIGRIINPGSKKGFEIYKFLGTLFSVQTVGNRNYQLLSNSTIGRSGLYQPAYESRDCQELCFWIEIAATTKAGLSSNDLITFCGTGGSMPDVNW 4mc7 D 2.99 BS01 CA D 1 N281 D285 A286 D311 G329 G331 G332 N207 D211 A212 D237 G255 G257 G258 ATPLVLGENLCSINGWVPTYRGEGTTGKIPDEQMLTRQNFVSCSDKECRRFFVSMGYGTTTNFADLIVSEQMNVYSVKLGDPPTPDKLKFEAVGWSASSCHDGFQWTVLSVAGDGFVSILYGGIITDTIHPTNGGPLRTQASSCICNDGTCYTIIADGTTYTASSHRLYRLVNGTSAGWKALDTTGFNFEFPTCYYTSGKVKCTGTNLWNDAKRPFLEFDQSFTYTFKEPCLGFLGDTPRGIDTTNYCDKTTTEGEGGIQGFMIEGSNSWIGRIINPGSKKGFEIYKFLGTLFSVQTVGNRNYQLLSNSTIGRSGLYQPAYESRDCQELCFWIEIAATTKAGLSSNDLITFCGTGGSMPDVNW 4mdx A 1.50 BS01 NUC C 1 N32 I34 G35 F38 S39 P40 T41 N33 I35 G36 F39 S40 P41 T42 3.1.-.- P96622 SMIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQIRTIDKQRLTDKITHLDDEMMDKVDEALQISLALI 4mdx B 1.50 BS01 NUC C 1 F10 G18 S19 E20 Q21 G22 V24 R25 P26 I47 T48 A49 Q50 K53 L56 P57 T58 H59 F69 E70 S73 E78 Q79 D90 F11 G19 S20 E21 Q22 G23 V25 R26 P27 I48 T49 A50 Q51 K54 L57 P58 T59 H60 F70 E71 S74 E79 Q80 D91 3.1.-.- P96622 SMIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQIRTIDKQRLTDKITHLDDEMMDKVDEALQISLALI 4mqb A 1.55 BS01 MES A 1 E37 R48 F66 R70 R92 S96 S97 E37 R48 F66 R70 R92 S96 S97 2.7.4.9 P65248 MSAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTGEEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAYQGYARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSRDQNRLDQEDLKFHEKVIEGYQEIIHSQRFKSVNADQPLENVVEDTYQTIIKYLEKI 4mqy A 2.00 BS02 2CW A 1 L18 L62 E78 H79 T191 F192 G193 M195 I198 Q202 G210 S211 F212 A215 H238 D242 H265 L18 L62 E78 H79 T191 F192 G193 M195 I198 Q202 G210 S211 F212 A215 H238 D242 H265 3.5.1.- D5CV28 24117400 MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSA 4msf A 1.98 BS01 HEM A 1 M101 G104 Q105 D108 D112 F113 A114 E258 Q259 T344 F347 R348 G350 H351 V354 F380 L417 L433 I436 R440 M101 G104 Q105 D108 D112 F113 A114 E258 Q259 T344 F347 R348 G350 H351 V354 F380 L417 L433 I436 R440 1.11.1.7 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4msf A 1.98 BS03 3HY A 1 H109 R255 E258 F381 P424 H109 R255 E258 F381 P424 1.11.1.7 A3F9D6 SWEVGCGAPVPLVTCDEQSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCVQGDECFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELRNKLFQPTHKVHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSAVDKLDLSPWASREN 4mtl A 1.65 BS01 SAH A 1 G88 V90 V91 W92 A95 G120 A121 G122 D141 L142 V145 L170 V171 W172 S193 D194 Y197 F201 G32 V34 V35 W36 A39 G64 A65 G66 D85 L86 V89 L114 V115 W116 S137 D138 Y141 F145 2.1.1.- Q5VZV1 KFVPTDYASYTQEHYRFAGKEIVIQESIESYGAVVWPGAMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYFLDKLLTTMVYLSQPGTVLLWANKFRFSTDYEFLDKFKQVFDTTLLAEYPESSVKLFKGILKWD 4mtl B 1.65 BS01 SAH B 1 V91 W92 A95 G120 A121 G122 D141 L142 L170 V171 W172 S193 D194 Y200 V47 W48 A51 G76 A77 G78 D97 L98 L126 V127 W128 S149 D150 Y156 2.1.1.- Q5VZV1 SNKIEPSLHSLQKFVPTDYASYTQEHYRFAGKEIVIQESIESYGAVVWPGAMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYFLDKLLTTMVYLSQPGTVLLWANKFRFSTDYEFLDKFKQVFDTTLLAEYPESSVKLFKGILKW 4muw A 2.64 BS02 2F4 A 1 Y514 H515 L625 V668 I682 Y683 F686 P702 M703 K708 E711 V712 G715 Q716 F719 Y73 H74 L184 V227 I241 Y242 F245 P261 M262 K267 E270 V271 G274 Q275 F278 3.1.4.17,3.1.4.35 Q9Y233 24102193 TSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4mvh A 2.50 BS02 2F5 A 1 Y514 S667 V668 I682 Y683 F686 P702 M703 K708 E711 V712 G715 Q716 F719 Y62 S215 V216 I230 Y231 F234 P250 M251 K256 E259 V260 G263 Q264 F267 3.1.4.17,3.1.4.35 Q9Y233 24102193 TLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4mvh B 2.50 BS02 2F5 B 1 Y514 L665 S667 V668 I682 Y683 F686 P702 M703 E711 V712 G715 Q716 F719 Y63 L214 S216 V217 I231 Y232 F235 P251 M252 E260 V261 G264 Q265 F268 3.1.4.17,3.1.4.35 Q9Y233 24102193 FTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4mzy A 1.95 BS01 PO4 A 1 N293 D294 G316 T317 N291 D292 G314 T315 2.4.2.11 Q830Y8 YTYADDSLTLHTDMYQINMMQTYWELGRADLHAVFECYFREMPFNHGYAIFAGLERLVNYLENLTFTESDIAYLREVEEYPEDFLTYLANFEFKCTVRSALEGDLVFNNEPLIQIEGPLAQCQLVETALLNMVNFQTLIATKAARIKSVIGDDPLLEFGTRRAQELDAAIWGTRAAYIGGADATSNVRAGKIFGIPVSGTHAHSLVQSYGNDYEAFMAYAKTHRDCVFLVDTYDTLKAGVPSAIRVAREMGDKINFLGVRIDSGDMAYISKRVREQLDEAGFTEAKIYASNDLDENTILNLKMQKSKIDVWGVGTKLITAYDQPALGAVFKLVSIEGEDGQMKDTIKLSSNAEKVTTPGKKQVWRITRKSDKKSEGDYVTLWNEDPRQEEEIYMFHPVHTFINKYVRDFEARPVLQDIFVEGKRVYELPTLDEIKQYAKENLDSLHEEYKRDLNPQKYPVDLSTDCWNHKMNLLEKVRKDVKHLTE