3j4p A 4.80 BS01 SCR A 1 R587 R590 R367 R370 24036405 VGNSSGNWHCDSTWMGDRVITTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLSFKLFNIQVKEVTQNEGTKTIANNLTSTIQVFTDSEYQLPYVLGSAHQGCLPPFPADVFMIPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFQFTYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTQTTGGTTNTQTLGFSQGGPNTMANQAKNWLPGPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQGVLPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPADPPTTFNQSKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSTSVDFAVNTEGVYSEPRPIGTRYLTRNL 3vwq A 1.70 BS01 ACA A 1 M111 A112 D181 W186 Y215 F264 N266 G344 I345 M103 A104 D173 W178 Y207 F256 N258 G336 I337 3.5.1.46 Q59710 STGQHPARYPGAAAGEPTLDSWQEPPHNRWAFAHLGEMVPSAAVSRRPGHALARLGAIAAQLPDLEQRLEQTYTDAFLVLRGTEVVAEYYRAGFAPDDRHLLMAVSKSLCGTVVGALVDEGRIDPAQPVTEYVPELAGSVYDGPSVLQVLDMQISIDYNEDYVDPASEVQTHDRSAGWATRRHGDPADTYEFLTTLRGDGSTGEFQYCSANTDVLAWIVERVTGLRYVEALSTYLWAKLDADRDATITVDTTGFGFANGGVSCTARDLARVGRMMLDGGVAPGGRVVSEDWVRRVLAGGSHEAMTDKGFTNTFPDGSYTRQWWCTGNERGNVSGIGIHGQNLWLDPLTDSVIVKLSSWPDPYTEHWHRLQNGILLDVSRALDAV 3w2v A 2.60 BS02 3AM A 1 V229 Q230 I233 S246 L249 N300 K301 Y669 D674 V13 Q14 I17 S30 L33 N84 K85 Y408 D413 Q8U1S6 23583914 KDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFEGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLEEGVGKRFIYHVLREVDTWPKVGIDEMLKFEVIRHIRGRNKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 3w2w A 2.50 BS02 ATP A 1 K225 V227 V229 Q230 I233 S246 L249 N300 R436 Y669 D674 K10 V12 V14 Q15 I18 S31 L34 N85 R221 Y421 D426 Q8U1S6 23583914 VKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFELLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLEEGVGKRFIYHVLREVDTWPKVGIDEMLKFEVIRHIRGRNKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 3w2w A 2.50 BS03 ATP A 2 Y271 K301 D600 G601 D602 D603 M604 G605 I608 H642 L649 K739 K744 Y56 K86 D374 G375 D376 D377 M378 G379 I382 H394 L401 K488 K493 Q8U1S6 23583914 VKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFELLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLEEGVGKRFIYHVLREVDTWPKVGIDEMLKFEVIRHIRGRNKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 3w2w A 2.50 BS04 MG A 1 D600 G601 D374 G375 Q8U1S6 23583914 VKDPTLLRIKIVPVQPFIANSRKQLDLWASSHLLSMLMYKALEVIVDKFGPEHVIYPSLRDQPFFLKFYLGENIGDEILVANLPNKALAIVSGKEAEKIEEEIKKRIRDFLLQLYREAVDWAVENGVVKVDRSEKDSMLKEAYLKIVREYFTVSITWVSLSEKEDIYQVTENAGLSDEDVKKWLKFAEKKENSRVLERIAIYPLLVKILDSLGERKVTEERFEKSEQLKGWKCHVCGENLAIFGDMYDHDNLKSLWLDEEPLCPMCLIKRYYPVWIRSKTGQKIRFESVVDVALLYKNWRKIFDEKYGKDLVSKAREVSEDFVKDNMLVDSDLYYSSTWESGDEEKVKEVVDFLNAAYKEIGNPPKYYAILVMDGDDMGKVISGEVLYSTPQVHVAISQALANFSIREVRSVVKDEGLLIYAGGDDVLAILPVDKALEVAYKIRKEFGKSFELLPGWKLSAGILIVHYKHPLYDALEKARDLLNNKAKNVPGKDTLAIGLLKRSGSYYISLVGWELIRVFYNSELRKKLLEEGVGKRFIYHVLREVDTWPKVGIDEMLKFEVIRHIRGRNKEETKELREKIYGEIKDLLEHVRGNNEVEKVRGLFTFLKIITDAEVFP 3wbd B 1.80 BS01 SIA B 1 Y54 R55 F60 Y159 D232 Y55 R56 F61 Y145 D218 SDVVMTQTPLSLPVSLGDQASISCRSSQSLVHSNGNTYLYWYLQKPGQSPKPLIYRVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCFQGTHVPYTFGGGTRLEIKQIQLQQSGPELVRPGASVKISCKASGYTFTDYYIHWVKQRPGEGLEWIGWIYPGSGNTKYNEKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYFCARGGKFAMDYWGQGTSVTVSS 3wbd B 1.80 BS02 SIA B 2 N33 N35 Y37 R55 N34 N36 Y38 R56 SDVVMTQTPLSLPVSLGDQASISCRSSQSLVHSNGNTYLYWYLQKPGQSPKPLIYRVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCFQGTHVPYTFGGGTRLEIKQIQLQQSGPELVRPGASVKISCKASGYTFTDYYIHWVKQRPGEGLEWIGWIYPGSGNTKYNEKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYFCARGGKFAMDYWGQGTSVTVSS 3wbd B 1.80 BS03 SIA B 3 Y160 Y179 Y146 Y165 SDVVMTQTPLSLPVSLGDQASISCRSSQSLVHSNGNTYLYWYLQKPGQSPKPLIYRVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCFQGTHVPYTFGGGTRLEIKQIQLQQSGPELVRPGASVKISCKASGYTFTDYYIHWVKQRPGEGLEWIGWIYPGSGNTKYNEKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYFCARGGKFAMDYWGQGTSVTVSS 3zj0 A 1.80 BS01 ACO A 1 T25 G29 H135 I136 D137 L138 Q143 G144 R145 G146 V147 G148 S149 L169 Q170 N175 R177 G180 F181 Y182 H184 T23 G27 H133 I134 D135 L136 Q141 G142 R143 G144 V145 G146 S147 L167 Q168 N173 R175 G178 F179 Y180 H182 Q2CEE2 24088714 SEVVIRRATAADHGDLCRVCLLTGDSGRDASSREDDPTLLGMIYAVPYQVGAPDFAFVLEDAEGVCGYLLGAPDTLSFQHFLEKEWLPPLRAGLTDPGPDPAAWQGSDWARDAIHRPPALPPIDLAAYPAHGHIDLLPRAQGRGVGSRAMDHLEAALAAAGAPGMHLQVSPENPRALGFYEHRGFRELCRSEDEVVVGRRLL 4bbo A 1.60 BS01 BTN A 1 N9 Y11 S13 Y31 N33 S38 C39 F66 S71 T73 W75 W89 L91 D107 N9 Y11 S13 Y31 N33 S38 C39 F66 S71 T73 W75 W89 L91 D107 Q89IH6 QSVNWTWTNQYGSTLAITSFNSNTGAITGTYTNNAANSCDEGKPQGVTGWLAYGNTGTAISFSVNFLGCGSTTVWTGQLNNATGFQGLWYLSLAEAVAWNGISAGADTFTFSS 4bbp A 2.15 BS01 YU7 A 1 L32 G56 A57 S58 H139 H140 H147 H211 E260 P261 Q262 D283 L285 T287 L6 G30 A31 S32 H91 H92 H99 H163 E212 P213 Q214 D235 L237 T239 B5N507 AVVASLKPLGFIASAIADGVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKHHHGEYNMHLWLSPEIARATAVAIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD 4bbp A 2.15 BS02 ZN A 1 H139 H140 H147 H211 H91 H92 H99 H163 B5N507 AVVASLKPLGFIASAIADGVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKHHHGEYNMHLWLSPEIARATAVAIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD 4bbx A 2.50 BS01 LKF A 1 Y514 S561 L625 L665 I682 F686 M703 M704 Q716 F719 Y67 S114 L178 L218 I235 F239 M256 M257 Q269 F272 3.1.4.17,3.1.4.35 Q9Y233 GLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4bbx B 2.50 BS01 LKF B 1 Y514 L625 F629 L665 I682 Y683 F686 M703 Q716 F719 Y67 L178 F182 L218 I235 Y236 F239 M256 Q269 F272 3.1.4.17,3.1.4.35 Q9Y233 GLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4bcs A 1.80 BS01 BTN A 1 D12 L14 S16 Y33 T35 V37 A38 D39 W68 F70 S71 T75 W95 N116 D10 L12 S14 Y31 T33 V35 A36 D37 W66 F68 S69 T73 W93 N114 KCSLTGKWTDDLGSNMTIGAVNSRGEFTGTYITAVADNPGNITLSPLLGIQHKRASQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLRSSVNDISDDWIATRVGINIFTRQRTQK 4bs0 A 1.09 BS01 6NT A 1 A21 W44 E46 Q50 G83 C84 D127 M172 L236 M237 T265 M267 A18 W41 E43 Q47 G80 C81 D124 M169 L233 M234 T262 M264 4.-.-.- P23360 QSIDQLIKARGKVYFGVATDQNRLTTGKNAAIIKADFGMVWPENSMQWDATEPSQGNFNFAGADYLVNWAQQNGKLIGAGCLVWHNFLPSWVSSITDKNTLINVMKNHITTLMTRYKGKIRTWDVVGEAFNEDGSLRQNVFLNVIGEDYIPIAFQTARAADPNAKLYIMDYNLDSASYPKTQAIVNRVKQWRAAGVPIDGIGSQMHLSAGQGAGVLQALPLLASAGTPEVSILMLDVAGASPTDYVNVVNACLNVQSCVGITVMGVADPDSAFASSTPLLFDGNFNPKPAYNAIVQDLQ 4by6 A 2.80 BS01 CA A 1 D1915 D1918 D1931 D346 D349 D362 P25655 TRTEKFYLVFTEWVKLLQRVENNDVITTVFIKQLVEKGVISDTDNLLTFVKSSLELSVSSFKESDPTDEVFIAIDALGSLIIKLLILQDFKTRRDYINAIFSVIVLVFAKDHSQEGTTFNERPYFRLFSNILYEWATIRTHNFVRISDSSTRQELIEFDSVFYNTFSGYLHALQPFAFPGFSFAWVTLLSHRMLLPIMLRLPNKIGWEKLMLLIIDLFKFLDQYTSKHAVDAVSVVYKGTLRIILGISNDMPSFLIENHYELMNNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDIPACKELPEVFFDPVIDLHSLKKPVDNYLRIPSNSLLRTILSAIYKDTYDIKKGVGYDFLSVDSKLIRAIVLHVGIEAGIEYKRTNAVFNTKSSYYTLLFNLIQNGSIEMKYQIILSIVEQLRYPNIHTYWFSFVLMNMFKSDEWNDQKLEVQEIILRNFLKRIIVNKPHTWGVSVFFTQLINNNDINLLDLPFVQSVPEIKLILQQLV 4c1q A 2.30 BS01 III C 1 Y276 A287 N288 G290 S292 W293 L294 Y304 R317 F333 Y357 G358 E360 Y361 E364 Y82 A93 N94 G96 S98 W99 L100 Y110 R123 F139 Y163 G164 E166 Y167 E170 2.1.1.43 Q96EQ9 24095733 AMSQDDDYLYCEKCQNFFIDSCPNHGPPLFVKDSMVDRGHPNHSVLSLPPGLRISPSGIPEAGLGVWNEASDLPVGLHFGPYEGQITEDEEAANSGYSWLITKGRNCYEYVDGQDESQANWMRYVNCARDDEEQNLVAFQYHRKIFYRTCRVIRPGCELLVWYGDEYGQELGI 4c1q A 2.30 BS02 SAH A 1 I253 A256 G257 L258 Y291 R317 N320 C321 R323 Y357 Y361 L365 I59 A62 G63 L64 Y97 R123 N126 C127 R129 Y163 Y167 L171 2.1.1.43 Q96EQ9 24095733 AMSQDDDYLYCEKCQNFFIDSCPNHGPPLFVKDSMVDRGHPNHSVLSLPPGLRISPSGIPEAGLGVWNEASDLPVGLHFGPYEGQITEDEEAANSGYSWLITKGRNCYEYVDGQDESQANWMRYVNCARDDEEQNLVAFQYHRKIFYRTCRVIRPGCELLVWYGDEYGQELGI 4c1q A 2.30 BS03 ZN A 1 C205 C208 C216 H219 C11 C14 C22 H25 2.1.1.43 Q96EQ9 24095733 AMSQDDDYLYCEKCQNFFIDSCPNHGPPLFVKDSMVDRGHPNHSVLSLPPGLRISPSGIPEAGLGVWNEASDLPVGLHFGPYEGQITEDEEAANSGYSWLITKGRNCYEYVDGQDESQANWMRYVNCARDDEEQNLVAFQYHRKIFYRTCRVIRPGCELLVWYGDEYGQELGI 4c7w A 2.50 BS01 SIO A 1 L119 I166 Y189 F212 K217 G218 S219 S220 N253 L260 Y281 L83 I130 Y153 F176 K181 G182 S183 S184 N217 L224 Y245 3.1.1.53 O55252 22291594 FNEPLNIVSHLNDDWFLFGDARSDCTPKLDWLDLDPKLCNSGRISAKSGNSLFRSFHFIDFYNYSGEGDQVIFYEGVHGFKCLAYGDNKRWMGNKARFYARVYEKMAQYRSLSFVNVSYAYGGNAKPTSICKDKTLTLNNPTFISKESNYVDYYYESEANFTLQGCDEFIVPLCVFNGHSKGSSSDPANKYYTDSQSYYNMDTGVLYGFNSTLDVGNTVQNPGLDLTCRYLALTPGNYKAVSLEYLLSLPSKAICLRKPKSFMPVQVVDSDNMTAVACQLPYCFFRNTSAFHFRQLLSGLLYNVSCIAQQGAFVYNNVSSSWPAYGYGHCPTAANIGYMAPVCIYDSDPLVPR 4c8b A 2.75 BS01 0LI A 1 A45 V46 K47 E66 L70 I78 L79 I93 T95 E96 Y97 M98 L143 H144 L153 I162 A163 D164 F165 A38 V39 K40 E59 L63 I71 L72 I86 T88 E89 Y90 M91 L136 H137 L146 I155 A156 D157 F158 2.7.11.1,2.7.10.2 O43353 SALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGTIIYMPPENYSIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQS 4c8b B 2.75 BS01 0LI B 1 A45 K47 E66 L70 L79 T95 E96 Y97 M98 L143 H144 L153 I162 A163 D164 F165 A37 K39 E53 L57 L66 T82 E83 Y84 M85 L130 H131 L140 I149 A150 D151 F152 2.7.11.1,2.7.10.2 O43353 ALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQS 4c8d A 2.18 BS01 MN A 1 H1560 D1562 H1689 H175 D177 H301 1.14.11.- Q7LBC6 TSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEF 4c8q B 3.70 BS01 CO C 1 E18 R68 Y69 E28 R78 Y79 P38203 SENLYFQGSGSLFFSFFKTLVDQEVVVELKNDIEIKGTLQSVDQFLNLKLDNISCTDEKKYPHLGSVRNIFIRGSTVRYVYLNKNMVDTNLLQDATRREVMTER 4c8q C 3.70 BS01 CO C 1 R24 E46 I48 R61 R24 E46 I48 R61 P57743 METPLDLLKLNLDERVYIKLRGARTLVGTLQAFDSHCNIVLSDAVETIYQLNNEELSESERRCEMVFIRGDTVTLISTP 4c94 A 3.00 BS01 KXN A 1 L59 S63 H70 R139 L61 S65 H72 R141 D0E0C7 AMAGVFTYESEFTSVIPPPKLFKAFVLDADNLIPKIAPQAVKSAEIIEGDGGVGTIKKIHLGEGSEYSYVKHKIDGIDKDNFVYSYSIIEGDAIGDKIEKISYEIKLVASGGGSIIKSTSHYHTKGEVEIKEEHVKAGKERAAGLFKIIENHLLAHPEEYN 4c94 B 3.00 BS01 KXN B 1 I31 L59 H70 R139 I33 L61 H72 R141 D0E0C7 AMAGVFTYESEFTSVIPPPKLFKAFVLDADNLIPKIAPQAVKSAEIIEGDGGVGTIKKIHLGEGSEYSYVKHKIDGIDKDNFVYSYSIIEGDAIGDKIEKISYEIKLVASGGGSIIKSTSHYHTKGEVEIKEEHVKAGKERAAGLFKIIENHLLAHPEEYN 4c94 D 3.00 BS01 KXN D 1 F23 L59 H70 R139 F25 L61 H67 R136 D0E0C7 AMAGVFTYESEFTSVIPPPKLFKAFVLDADNLIPKIAPQAVKSAEIIEGDGGVGTIKKIHLGSYVKHKIDGIDKDNFVYSYSIIEGDAIGDKIEKISYEIKLVASGGGSIIKSTSHYHTKGEVEIKEEHVKAGKERAAGLFKIIENHLLAHPEEYN 4c94 E 3.00 BS01 KXN E 1 D28 A38 I57 L59 S63 H70 R139 L143 D30 A40 I59 L61 S65 H72 R141 L145 D0E0C7 AMAGVFTYESEFTSVIPPPKLFKAFVLDADNLIPKIAPQAVKSAEIIEGDGGVGTIKKIHLGEGSEYSYVKHKIDGIDKDNFVYSYSIIEGDAIGDKIEKISYEIKLVASGGGSIIKSTSHYHTKGEVEIKEEHVKAGKERAAGLFKIIENHLLAHPEEYN 4c94 E 3.00 BS02 KXN E 2 E61 G62 E63 G64 D0E0C7 AMAGVFTYESEFTSVIPPPKLFKAFVLDADNLIPKIAPQAVKSAEIIEGDGGVGTIKKIHLGEGSEYSYVKHKIDGIDKDNFVYSYSIIEGDAIGDKIEKISYEIKLVASGGGSIIKSTSHYHTKGEVEIKEEHVKAGKERAAGLFKIIENHLLAHPEEYN 4c9i F 3.10 BS01 KXN F 1 H143 K146 L147 G150 Y151 D154 H145 K148 L149 G152 Y153 D156 Q256S2 AMAGVYTYENEFTSDIPAPKLFKAFVLDADNLIPKIAPQAVKCAEILEGDGGPGTIKKITFGEGSHYGYVKHKIHSIDKVNHTYSYSLIEGDALSENIEKIDYETKLVSAPHGGTIIKTTSKYHTKGDVEIKEEHVKAGKEKAAHLFKLIEGYLKDHPSEYN 4e0f A 2.85 BS01 RBF A 1 S40 V46 C47 L48 T49 E66 A67 W68 E70 A71 G105 H106 V107 S40 V46 C47 L48 T49 E66 A67 W68 E70 A71 G105 H106 V107 2.5.1.9 G8SX20 MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNARWFEVEAWEEALRLTTISSWQSGRKINLERSLKLGDEMGGHLVFGHVDGQAEIVERKDEGDAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEFDVLLIRHSLEVTTWGERKAGDKVNIEIDQLARYAARLAQY 4e0f B 2.85 BS01 RBF A 1 K140 T151 I165 K140 T151 I165 2.5.1.9 G8SX20 MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNARWFEVEAWEEALRLTTISSWQSGRKINLERSLKLGDEMGGHLVFGHVDGQAEIVERKDEGDAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEFDVLLIRHSLEVTTWGERKAGDKVNIEIDQLARYAARLAQYQKL 4frr B 2.20 BS01 0VC C 1 R79 V108 M116 I118 R82 V111 M119 I121 Q8WSF8 DDKLHSQANLMRLKSDLFNRSPYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4frr C 2.20 BS01 0VC C 1 Y93 W147 V148 Y195 Y95 W149 V150 Y197 Q8WSF8 DKLHSQANLMRLKSDLFNRSPYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR 4gwt A 2.25 BS01 LMR A 1 P9 G10 H27 P4 G5 H22 5.2.1.8 Q13526 KLPPGWEKRMSRSSGRVYYFNHITNASQWERPS 4gwv A 3.05 BS01 FLC A 1 S16 R17 S18 W34 S11 R12 S13 W29 5.2.1.8 Q13526 KLPPGWEKRMSRSSGRVYYFNHITNASQWERPS 4h25 A 2.20 BS01 III C 1 Q9 N15 P16 F24 F32 W43 A52 S53 F54 N62 V65 A68 N69 E71 I72 M73 R76 Y79 Q7 N13 P14 F22 F30 W41 A50 S51 F52 N60 V63 A66 N67 E69 I70 M71 R74 Y77 P01903 23091041 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDA 4h25 B 2.20 BS01 III C 1 P5 F7 L11 S13 F26 E28 Y30 F37 W61 Q64 L67 K71 Q74 T77 Y78 H81 N82 V85 P3 F5 L9 S11 F24 E26 Y28 F35 W59 Q62 L65 K69 Q72 T75 Y76 H79 N80 V83 B8YAC7 23091041 TRPRFLELLKSECHFFNGTERVRFLERYFHNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDTYCRHNYGVVESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA 4h25 D 2.20 BS01 III F 1 Q9 F24 A52 S53 F54 N62 V65 K67 A68 N69 E71 I72 M73 R76 Y79 Q7 F22 A50 S51 F52 N60 V63 K65 A66 N67 E69 I70 M71 R74 Y77 P01903 23091041 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDA 4h25 E 2.20 BS01 III F 1 R4 P5 F7 L11 S13 F26 E28 Y30 F37 V57 W61 Q64 K71 Q74 T77 Y78 H81 N82 V85 V86 R2 P3 F5 L9 S11 F24 E26 Y28 F35 V55 W59 Q62 K69 Q72 T75 Y76 H79 N80 V83 V84 B8YAC7 23091041 TRPRFLELLKSECHFFNGTERVRFLERYFHNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDTYCRHNYGVVESFTVQRRVHPQVTVYPAKTNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA 4h26 A 2.50 BS01 III C 1 Q9 F24 F32 W43 A52 S53 F54 E55 N62 V65 A68 N69 I72 M73 Q7 F22 F30 W41 A50 S51 F52 E53 N60 V63 A66 N67 I70 M71 P01903 23091041 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4h26 B 2.50 BS01 III C 1 L11 S13 F26 E28 Y30 F37 V57 W61 Q64 L67 K71 Q74 T77 Y78 H81 N82 V85 L9 S11 F24 E26 Y28 F35 V55 W59 Q62 L65 K69 Q72 T75 Y76 H79 N80 V83 B8YAC7 23091041 TRPRFLELLKSECHFFNGTERVRFLERYFHNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGQVDTYCRHNYGVVESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA 4h26 D 2.50 BS01 III F 1 Q9 F24 F32 A52 S53 F54 N62 V65 N69 I72 M73 Q7 F22 F30 A50 S51 F52 N60 V63 N67 I70 M71 P01903 23091041 EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFD 4her E 1.60 BS01 URI F 1 H5 R45 H5 R45 Q8E9X9 ADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPVVICSTGIGGPSTSIAVEELAQLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTFYPGQERYDTVTGRVTRRFAGSMKEWQDMGVLNYEMESATLFTMCATQGWRAACVAGVIVNRTQKTEVSAVSIVVAAAKKLLA 4her F 1.60 BS01 URI F 1 R88 T91 T92 G93 F159 Q163 R165 Y192 E193 M194 E195 R88 T91 T92 G93 F159 Q163 R165 Y192 E193 M194 E195 Q8E9X9 ADVFHLGLTKAMLDGATLAIVPGDPERVKRIAELMDNATFLASHREYTSYLAYADGKPVVICSTGIGGPSTSIAVEELAQLGVNTFLRVGTTGAIQPHVNVGDVIVTQASVRLDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEPHIGVTASSDTFYPGQERYDTVTGRVTRRFAGSMKEWQDMGVLNYEMESATLFTMCATQGWRAACVAGVIVNRTQQEIPVSAVSIVVAAAKKLLA 4hi0 E 2.35 BS01 GDP E 1 G11 S12 G13 K14 T15 A16 N145 K146 D148 N177 I178 R179 G11 S12 G13 K14 T15 A16 N145 K146 D148 N177 I178 R179 Q09066 MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRERIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNAL 4hi0 E 2.35 BS02 GDP F 1 A123 E124 A123 E124 Q09066 MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRERIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNAL 4hil A 1.25 BS01 HEM A 1 I32 F35 H39 P40 G41 V45 L46 Q49 A54 S57 F58 V61 H63 S64 A67 M70 L71 I31 F34 H38 P39 G40 V44 L45 Q48 A53 S56 F57 V60 H62 S63 A66 M69 L70 P04166 PAVTYYRLEEVAKRNTAEETWMVIHGRVYDITRFLSEHPGGEEVLLEQAGADATESFEDVGHSPDAREMLKQYYIGDVHPNDLKP 4hil B 1.25 BS01 HEM B 1 M23 I25 F35 H39 P40 G41 V45 L46 A54 F58 V61 H63 S64 A67 M70 L71 M20 I22 F32 H36 P37 G38 V42 L43 A51 F55 V58 H60 S61 A64 M67 L68 P04166 VTYYRLEEVAKRNTAEETWMVIHGRVYDITRFLSEHPGGEEVLLEQAGADATESFEDVGHSPDAREMLKQYYIGDVHPNDL 4hin A 2.40 BS01 HEM A 1 L32 F35 H39 P40 G41 V45 L46 Q49 A54 F58 V61 H63 S64 A67 L71 L29 F32 H36 P37 G38 V42 L43 Q46 A51 F55 V58 H60 S61 A64 L68 P00171 VKYYTLEEIQKHNNSKSTWLILHYKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELLKTFIIGELHPDDR 4hin C 2.40 BS01 HEM C 1 L32 F35 H39 P40 G41 L46 A54 F58 V61 H63 S64 A67 L71 F74 L30 F33 H37 P38 G39 L44 A52 F56 V59 H61 S62 A65 L69 F72 P00171 AVKYYTLEEIQKHNNSKSTWLILHYKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELLKTFIIGELHPDDR 4how A 1.70 BS01 CA A 1 D63 T64 N65 D67 I69 D71 D22 T23 N24 D26 I28 D30 5.4.99.11 D9MPF2 24069347 NALPTWWKQAVFYQVYPRSFKDTNGDGIGDLNGIIENLDYLKKLGIDAIWINPHYDSPNTDNGYDIRDYRKIMKEYGTMEDFDRLISEMKKRNMRLMIDIVINHTSDQHAWFVQSKSGKNNPYRDYYFWRDGKDGHAPNNYPSFFGGSAWEKDDKSGQYYLHYFAKQQPDLNWDNPKVRQDLYDMLRFWLDKGVSGLRFDTVATYSKIPNFPDLSQQQLKNFAEEYTKGPKIHDYVNEMNREVLSHYDIATAGEIFGVPLDKSIKFFDRRRNELNIAFTFDLIRLDRDADERWRRKDWTLSQFRKIVDKVDQTAGEYGWNAFFLDNHDNPRAVSHFGDDRPQWREHAAKALATLTLTQRATPFIYQGSELGMTNYPFKKIDDFDDVEVKGFWQDYVETGKVKAEEFLQNVRQTSRDNSRTPFQWDASKNAGFTSGTPWLKINPNYKEINSADQINNPNSVFNYYRKLINIRHDIPALTYGSYIDLDPDNNSVYAYTRTLGAEKYLVVINFKEEVMHYTLPGDLSINKVITENNSHTIVNKNDRQLRLEPWQSGIYKLNP 4hoz A 2.00 BS01 CA A 1 D63 N65 D67 I69 D71 D22 N24 D26 I28 D30 5.4.99.11 D9MPF2 24069347 NALPTWWKQAVFYQVYPRSFKDTNGDGIGDLNGIIENLDYLKKLGIDAIWINPHYDSPNTDNGYDIRDYRKIMKEYGTMEDFDRLISEMKKRNMRLMIDIVINHTSDQHAWFVQSKSGKNNPYRDYYFWRDGKDGHAPNNYPSFFGGSAWEKDDKSGQYYLHYFAKQQPDLNWDNPKVRQDLYDMLRFWLDKGVSGLRFATVATYSKIPNFPDLSQQQLKNFAEEYTKGPKIHDYVNEMNREVLSHYDIATAGEIFGVPLDKSIKFFDRRRNELNIAFTFDLIRLDRDADERWRRKDWTLSQFRKIVDKVDQTAGEYGWNAFFLDNHDNPRAVSHFGDDRPQWREHAAKALATLTLTQRATPFIYQGSELGMTNYPFKKIDDFDDVEVKGFWQDYVETGKVKAEEFLQNVRQTSRDNSRTPFQWDASKNAGFTSGTPWLKINPNYKEINSADQINNPNSVFNYYRKLINIRHDIPALTYGSYIDLDPDNNSVYAYTRTLGAEKYLVVINFKEEVMHYTLPGDLSINKVITENNSHTIVNKNDRQLRLEPWQSGIYKLNP 4hoz A 2.00 BS02 GLC A 1 D102 Y105 H145 F186 F205 Q209 R239 A241 E295 H368 D369 R456 D61 Y64 H104 F145 F164 Q168 R198 A200 E254 H327 D328 R415 5.4.99.11 D9MPF2 24069347 NALPTWWKQAVFYQVYPRSFKDTNGDGIGDLNGIIENLDYLKKLGIDAIWINPHYDSPNTDNGYDIRDYRKIMKEYGTMEDFDRLISEMKKRNMRLMIDIVINHTSDQHAWFVQSKSGKNNPYRDYYFWRDGKDGHAPNNYPSFFGGSAWEKDDKSGQYYLHYFAKQQPDLNWDNPKVRQDLYDMLRFWLDKGVSGLRFATVATYSKIPNFPDLSQQQLKNFAEEYTKGPKIHDYVNEMNREVLSHYDIATAGEIFGVPLDKSIKFFDRRRNELNIAFTFDLIRLDRDADERWRRKDWTLSQFRKIVDKVDQTAGEYGWNAFFLDNHDNPRAVSHFGDDRPQWREHAAKALATLTLTQRATPFIYQGSELGMTNYPFKKIDDFDDVEVKGFWQDYVETGKVKAEEFLQNVRQTSRDNSRTPFQWDASKNAGFTSGTPWLKINPNYKEINSADQINNPNSVFNYYRKLINIRHDIPALTYGSYIDLDPDNNSVYAYTRTLGAEKYLVVINFKEEVMHYTLPGDLSINKVITENNSHTIVNKNDRQLRLEPWQSGIYKLNP 4hph A 1.70 BS02 SUC A 1 D102 Y105 H145 F186 F205 R239 D241 Q295 F297 H368 D369 E428 R456 D61 Y64 H104 F145 F164 R198 D200 Q254 F256 H327 D328 E387 R415 5.4.99.11 D9MPF2 24069347 NALPTWWKQAVFYQVYPRSFKDTNGDGIGDLNGIIENLDYLKKLGIDAIWINPHYDSPNTDNGYDIRDYRKIMKEYGTMEDFDRLISEMKKRNMRLMIDIVINHTSDQHAWFVQSKSGKNNPYRDYYFWRDGKDGHAPNNYPSFFGGSAWEKDDKSGQYYLHYFAKQQPDLNWDNPKVRQDLYDMLRFWLDKGVSGLRFDTVATYSKIPNFPDLSQQQLKNFAEEYTKGPKIHDYVNEMNREVLSHYDIATAGQIFGVPLDKSIKFFDRRRNELNIAFTFDLIRLDRDADERWRRKDWTLSQFRKIVDKVDQTAGEYGWNAFFLDNHDNPRAVSHFGDDRPQWREHAAKALATLTLTQRATPFIYQGSELGMTNYPFKKIDDFDDVEVKGFWQDYVETGKVKAEEFLQNVRQTSRDNSRTPFQWDASKNAGFTSGTPWLKINPNYKEINSADQINNPNSVFNYYRKLINIRHDIPALTYGSYIDLDPDNNSVYAYTRTLGAEKYLVVINFKEEVMHYTLPGDLSINKVITENNSHTIVNKNDRQLRLEPWQSGIYKLNP 4hr0 A 1.90 BS01 MN3 A 1 E69 E102 H105 E202 E68 E101 H104 E201 1.17.4.1 Q5KW80 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRTK 4hr0 A 1.90 BS02 FE A 1 E102 E167 E202 H205 E101 E166 E201 H204 1.17.4.1 Q5KW80 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRTK 4hr4 A 1.90 BS02 FE2 A 1 F98 E102 E167 E202 H205 F97 E101 E166 E201 H204 1.17.4.1 Q5KW80 VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGYVDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRTK 4hwz A 2.40 BS01 III C 1 M5 Y7 R62 N63 N66 V67 T73 D77 Y84 Y99 D116 Y123 T143 K146 W147 V152 Q155 W156 Y159 W167 Y171 M5 Y7 R62 N63 N66 V67 T73 D77 Y84 Y99 D116 Y123 T143 K146 W147 V152 Q155 W156 Y159 W167 Y171 P01891 23566939 GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQMMYGCDVGSDGRFLRGYRQDAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQWRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVPSGQEQRYTCHVQHEGLPKPLTLRW 4i5q A 1.96 BS01 MG A 1 S22 V24 M27 S28 V30 M33 P55890 23726983 AMDPEFMDAAIRQSLAKLGVQSTEIQASPVAGMKTVLTHSGVLYVTDDGKHIIQGPMYDVSGAHPVNVTNKLLMSQLNALEKEMIVYKAPDEKHVITVFTDITCGYCHKLHEEMKDYNALGITVRYLAFPRQGLESQAEQDMKSIWCAKDKNKAFDDAMAGKGVKPASCDVNIADHYALGVQLGVSGTPAIVLSNGYVVPGYQGPKEMKAFLDEHQKQTS 4i6q A 1.85 BS01 PHU A 1 F992 W1011 P1030 F1034 M1037 L1054 R1059 L1060 W1078 F172 W191 P210 F214 M217 L229 R234 L235 W253 2.7.10.2 P52333 23541670 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMVPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGS 4i6q A 1.85 BS02 1DT A 1 L828 G829 V836 A853 M902 E903 Y904 L905 G908 C909 R953 L956 A966 D967 L14 G15 V22 A39 M82 E83 Y84 L85 G88 C89 R133 L136 A146 D147 2.7.10.2 P52333 23541670 TIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMVPALSRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGS 4i7y H 2.40 BS01 III L 1 E23 I24 G25 M26 P28 W29 S115 D116 H119 P120 V121 C122 G133 Y134 K135 R137 N159 Y184A K186D M201 K202 P204 N205 R206 W207 E8 I9 G10 M11 P13 W14 S112 D113 H116 P117 V118 C119 G133 Y134 K135 R137 N156 Y182 K188 M203 K204 P206 N209 R210 W211 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 4i7y H 2.40 BS02 NUC D 1 Y89 I90 H91 P92 R93 Y94 N95 W96 R97 R101 R126 L130 K169 F181 H230 F232 R233 W237 K240 Q244 F245 Y85 I86 H87 P88 R89 Y90 N91 W92 R93 R98 R123 L130 K166 F178 H234 F236 R237 W241 K244 Q248 F249 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 4i7y H 2.40 BS03 0G6 H 1 H57 Y60A L99 D189 A190 G193 S195 S214 W215 G216 G219 G226 H43 Y47 L96 D191 A192 G195 S197 S218 W219 G220 G222 G230 3.4.21.5 P00734 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 4j0l A 1.90 BS01 NAG A 1 T69 G70 G71 R90 T69 G70 G71 R90 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4j0l A 1.90 BS02 NAG A 2 H66 T68 T69 F86 S210 H66 T68 T69 F86 S210 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4j0l A 1.90 BS03 NAG A 3 H66 Q67 F86 Q88 E89 R90 Q118 N199 E203 R211 R215 H66 Q67 F86 Q88 E89 R90 Q118 N199 E203 R211 R215 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4j0l A 1.90 BS04 NAG A 4 Q67 E89 Y96 Q118 S120 N199 L202 Q67 E89 Y96 Q118 S120 N199 L202 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4j0l A 1.90 BS05 NAG A 5 I117 S120 H121 Y123 N124 F157 K165 I198 I117 S120 H121 Y123 N124 F157 K165 I198 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4j0l A 1.90 BS06 NAG A 6 Y123 Q162 K165 G201 A243 Y123 Q162 K165 G201 A243 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4j0l A 1.90 BS07 NAG A 7 Y123 P164 A243 Y123 P164 A243 3.2.1.14 Q9FRV0 23871710 SVSSIISHAQFDRMLLHRNDGACQAKGFYTYDAFVAAANAFPGFGATGSTDARKRDVAAFLAQTSHQTTGGAATAPDGAFAWGYCFKQERGAAADYCTPSAQWPCAPGKRYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTALWFWMTAQAPKPSSHAVITGKWSPSGADRAAGRAPGFGVITNIINGGLECGHGQDSRVADRIGFYKRYCDILGVGYGDNLDCYNQRPFA 4jd9 D 2.60 BS01 SO4 D 1 A19 R89 I92 A16 R86 I89 Q06K46 24092749 ETPSQKCEEKYKERKACIHHCKYQYYGFIDVNYNIAQPEIRKFSNVLMDYGVVDRSKKRELKKVMHDCAKKIKKEARTGDHWLNCRTSIDYYRCVLTSKLIGPQRFDKAIQDYDKTISV 4jd9 F 2.60 BS01 SO4 F 1 R44 N48 K61 R41 N45 K58 Q06K46 24092749 ETPSQKCEEKYKERKACIHHCKYQYYGFIDVNYNIAQPEIRKFSNVLMDYGVVDRSKKRELKKVMHDCAKKIKKEARTGDHWLNCRTSIDYYRCVLTSKLIGPQRFDKAIQDYDKTISV 4jd9 F 2.60 BS02 SO4 F 2 R44 K45 N48 R41 K42 N45 Q06K46 24092749 ETPSQKCEEKYKERKACIHHCKYQYYGFIDVNYNIAQPEIRKFSNVLMDYGVVDRSKKRELKKVMHDCAKKIKKEARTGDHWLNCRTSIDYYRCVLTSKLIGPQRFDKAIQDYDKTISV 4jwf A 2.40 BS01 SAH A 1 L183 S184 A185 I202 G203 I205 D207 N209 Y211 L214 C215 K228 L229 K241 I242 L243 V248 L100 S101 A102 I119 G120 I122 D124 N126 Y128 L131 C132 K145 L146 K158 I159 L160 V165 2.1.1.221 O14214 24081582 RIRLGKVVPSSIRIVLDCAFDDLMNDKEINSLCQQVTRCHSANRTALHPVELFATNFGGRLKTRQDFVLKGQQNNWKRYNPTTKSYLEEFESQKEKLVYLSADSDNTITELDEDKIYIIGAIVDKNRYKNLCQNKASEQGIKTAKLPIDEYIKITDRKILTVNQVFEILSLWLEYRDWEKAFMEVIP 4jwj A 1.76 BS01 SAH A 1 L186 T187 A188 V205 G206 I208 D210 N212 Y214 L217 C218 R231 L232 R244 V245 L246 T248 V251 L105 T106 A107 V124 G125 I127 D129 N131 Y133 L136 C137 R150 L151 R163 V164 L165 T167 V170 2.1.1.221 Q12400 24081582 HMPRINVNQTDSGIEIILDCSFDELMNDKEIVSLSNQVTRAYSANRRANHFAEIKVAPFDKRLKQRFETTLKNTNYENWNHFKFLPDDKIMFGDEHISKDKIVYLTADTEEKLEKLEPGMRYIVGGIVDKNRYKELCLKKAQKMGIPTRRLPIDEYINLEGRRVLTTTHVVQLMLKYFDDHNWKNAFESVLPP 4k2i A 2.23 BS01 PMP A 1 S124 G125 T126 S150 F151 A153 D222 C224 Q225 S242 K247 Y379 S122 G123 T124 S148 F149 A151 D220 C222 Q223 S240 K245 Y377 O07566 KQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITTLSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQLVHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQ 4k2m A 1.71 BS01 O1G A 1 S124 G125 T126 S150 F151 A153 V196 D222 C224 Q225 S242 N244 Y246 K247 Y379 S126 G127 T128 S152 F153 A155 V198 D224 C226 Q227 S244 N246 Y248 K249 Y381 O07566 AGMQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITTLSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQLVHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIG 4k2m A 1.71 BS02 O1G B 1 T98 S99 Y274 K282 N292 T100 S101 Y276 K284 N294 O07566 AGMQKQVKISGKSKENMSLLKHLKGDVQGKELVIEDSIVNERWKQVLKEKIDIEHDLFNYQKNREISKVPFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCIDPDKIEEAITPYTKFILPVHLYGKHSDMQHIRQIANRYKLKVIEDACQGIGLTDLGKYADITTLSFNPYKNFGVCGKAGAIATDNEELAKKCIQFSYHGFEVNVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGVQTDVYYPILSHMQKTPLVQDKYAGLQLVHTEKAHSQVLHLPLYPSFTLEEQDRVMEGLFHVIKQEIG 4k7r A 2.09 BS01 3PK A 1 C1 F119 F120 I291 C1 F108 F109 I280 P77211 24099674 CSLAPDYQRPAMPVPQQFSLYQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRLTDADRYPQLNGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRAVHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQARGVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQILLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISLYTALGGG 4kjd A 2.21 BS01 MG A 1 S155 E311 S152 E308 3.1.3.1 P15693 24076154 VEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVTLRHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAD 4kjd A 2.21 BS02 MG A 2 E216 F269 E270 D285 E213 F266 E267 D282 3.1.3.1 P15693 24076154 VEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVTLRHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAD 4kjg A 2.38 BS01 ZN A 1 D316 H320 H432 D316 H320 H432 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHHHH 4kjg A 2.38 BS02 ZN A 2 D42 S92 D357 H358 D42 S92 D357 H358 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHHHH 4kjg A 2.38 BS03 MG A 1 D42 S155 E311 D42 S155 E311 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHHHH 4kjg A 2.38 BS05 MG A 3 S342 T345 S342 T345 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHHHH 4kjg A 2.38 BS06 4NP A 1 D91 S92 R166 D316 H432 D91 S92 R166 D316 H432 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHHHH 4kjg B 2.38 BS03 MG B 1 D42 S92 H153 S155 E311 D42 S92 H153 S155 E311 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHH 4kjg B 2.38 BS04 MG B 2 E216 F269 E270 K275 D285 E216 F269 E270 K275 D285 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHH 4kjg B 2.38 BS06 4NP B 1 D91 S92 R166 D316 H320 S429 H432 D91 S92 R166 D316 H320 S429 H432 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHH 4kjg B 2.38 BS07 NAG B 1 E216 W248 A284 E216 W248 A284 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHH 4kjg B 2.38 BS08 NAG B 2 G385 K386 N408 G385 K386 N408 3.1.3.1 P15693 24076154 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEHH 4l8b A 2.20 BS01 III C 1 Y7 E9 Y45 E63 K66 Q70 W73 F74 V76 S77 N80 L81 Y84 L95 Q97 F116 Y123 T143 K146 W147 S150 Y156 Y159 W167 Y171 Y7 E9 Y45 E63 K66 Q70 W73 F74 V76 S77 N80 L81 Y84 L95 Q97 F116 Y123 T143 K146 W147 S150 Y156 Y159 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEP 4l8c A 2.80 BS01 III I 1 M5 Y7 Y45 E63 K66 G69 Q70 W73 V76 S77 N80 Y84 L95 Q97 F116 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171 M5 Y7 Y45 E63 K66 G69 Q70 W73 V76 S77 N80 Y84 L95 Q97 F116 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWE 4l8c C 2.80 BS01 III J 1 Y7 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 F116 Y123 I124 T143 K146 W147 S150 H155 Y156 Y159 W167 Y171 Y7 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 F116 Y123 I124 T143 K146 W147 S150 H155 Y156 Y159 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWE 4l8d C 1.90 BS01 III F 1 Y7 E63 K66 W73 S77 N80 L81 Y84 L95 F116 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171 Y7 E63 K66 W73 S77 N80 L81 Y84 L95 F116 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171 P01899 GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPWMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGCDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSGAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRWEPP 4lcc C 3.26 BS01 1XL C 1 Y120 R122 S137 K156 Y175 W182 R207 I209 Y265 W269 Y91 R93 S104 K123 Y142 W149 R174 I176 Y232 W236 C1ITJ8 IQRPPKIQVYSRHPPNYLNCYVYGFHPPQIEIDLLKIKSEQSDLSFSKDWSFYLLSHATPNSKDQYSCRVKHVTLEQPRIVKWDRTHSLRYFRLGISEIPEFISAGYVDSHPITMYNSVSQLKEPRALWMEENLAPDHWERYTQLLRGWQQMFKVELKQLQHHYNHSGFHTYQRMIGCELLEDGSITGFLQYAYDGQDFLIFNKDTLSWMAMDNVADIIRRVWEANQHELLYQKNWLEEECIAWLKRFLEYGKDALQRTEPPKVRVNHKTTLYCRAYGFYPPEISINWMKNGEEIFQDTDYGGILPSGDGTYQTWVSVELGDIYSCHVEHGGVHMVLQGFQ 4lhc A 1.90 BS01 GLY A 1 Y134 C353 C530 H623 K726 W870 Y120 C329 C506 H599 K702 W835 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS02 GLY A 2 H623 G624 T625 H599 G600 T601 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS03 GLY A 3 L928 I929 G931 W933 Q939 L893 I894 G896 W898 Q904 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS04 GLY A 4 N647 V677 A680 G827 N828 N623 V653 A656 G792 N793 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS05 BCT A 1 S523 F863 E888 R891 W948 S499 F828 E853 R856 W913 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS06 BCT A 2 S82 Y84 S68 Y70 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS07 PO4 A 1 Q76 L77 P78 W573 Q62 L63 P64 W549 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc A 1.90 BS08 PO4 A 2 T151 D155 D494 S973 E975 T137 D141 D470 S938 E940 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTRSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc B 1.90 BS02 BCT B 1 F863 E888 R891 W948 F828 E853 R856 W913 1.4.4.2 P74416 EAIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhc B 1.90 BS03 PO4 B 1 D581 K745 S746 H747 D557 K721 S722 H723 1.4.4.2 P74416 EAIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhd A 1.80 BS01 GLY A 1 Y134 C353 H623 K726 W870 Y120 C339 H609 K712 W845 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTREQHIRRDKATSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhd A 1.80 BS03 GLY A 3 N647 V677 E679 A680 G827 N828 N633 V663 E665 A666 G802 N803 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQTREQHIRRDKATSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4lhd B 1.80 BS01 GLY B 1 Y134 C353 H623 W870 Y120 C327 H597 W833 1.4.4.2 P74416 AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITPPVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANASLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGIEVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRKMPGRIVGVSKDAHGNPALRLALQSNICTAQVLLAVMASMYGVYHGSTGLKNIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAEGRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSEVKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIPLGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGEITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTNPASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHKTFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVISWMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECILDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLGELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPYSQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM 4ljn A 3.00 BS01 ZN A 1 C281 C284 C307 C310 C85 C88 C111 C114 2.3.1.48 Q92794 ELPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKG 4ljn A 3.00 BS02 ZN A 2 C265 C268 H289 C292 C73 C76 H93 C96 2.3.1.48 Q92794 ELPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKG 4ljo A 1.56 BS01 ZN A 1 C871 C874 C890 C893 C15 C18 C34 C37 6.3.2.- Q96EP0 AQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK 4ljo A 1.56 BS02 ZN A 2 C898 C901 H926 C930 C42 C45 H70 C74 6.3.2.- Q96EP0 AQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK 4ljo A 1.56 BS03 ZN A 3 C911 C916 H923 H925 C55 C60 H67 H69 6.3.2.- Q96EP0 AQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK 4ljo A 1.56 BS04 ZN A 4 C969 C986 C998 H1001 C113 C130 C142 H145 6.3.2.- Q96EP0 AQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK 4ljo A 1.56 BS05 ZN A 5 C885 H887 C29 H31 6.3.2.- Q96EP0 AQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK 4ljq B 2.45 BS01 ZN B 1 C871 C874 C890 C893 C13 C16 C28 C31 6.3.2.- Q96EP0 QGLAMYLQEGIDCPKCKFSYALCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGCRVIEQKDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR 4ljq B 2.45 BS02 ZN B 2 C898 C901 H926 C930 C36 C39 H64 C68 6.3.2.- Q96EP0 QGLAMYLQEGIDCPKCKFSYALCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGCRVIEQKDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR 4ljq B 2.45 BS03 ZN B 3 C911 C916 H923 H925 C49 C54 H61 H63 6.3.2.- Q96EP0 QGLAMYLQEGIDCPKCKFSYALCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGCRVIEQKDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR 4ljq B 2.45 BS04 ZN B 4 C969 C986 C998 H1001 C98 C108 C120 H123 6.3.2.- Q96EP0 QGLAMYLQEGIDCPKCKFSYALCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGCRVIEQKDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR 4ljq B 2.45 BS05 ZN B 5 H887 H889 H25 H27 6.3.2.- Q96EP0 QGLAMYLQEGIDCPKCKFSYALCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGCRVIEQKDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR 4ljq D 2.45 BS04 ZN D 4 C969 V971 C986 C998 H1001 C98 V100 C106 C118 H121 6.3.2.- Q96EP0 GLAMYLQEGIDCPKCKFSYAGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPGGCRVIEDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRR 4lk9 A 1.60 BS01 III B 1 F211 C241 L242 K243 I260 E261 K263 Q271 A275 D276 M278 L279 F280 C281 D282 D285 M300 G303 F22 C52 L53 K54 I71 E72 K74 Q82 A86 D87 M89 L90 F91 C92 D93 D96 M111 G114 2.3.1.48 Q92794 HMLELPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKK 4llb A 2.50 BS01 III C 1 S210 F211 N235 S236 C241 L242 L248 W257 C259 I260 E261 K263 Q271 A275 D276 N277 M278 F280 C281 D282 D285 M300 S21 F22 N46 S47 C52 L53 L59 W68 C70 I71 E72 K74 Q82 A86 D87 N88 M89 F91 C92 D93 D96 M111 2.3.1.48 Q92794 HMLELPHEKDKPVAEPIPICSFCLGTKEQNREKKPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRP 4llz A 2.35 BS01 LUR A 1 Y348 V349 L352 Y385 W387 M522 V523 G526 A527 S530 Y317 V318 L321 Y354 W356 M491 V492 G495 A496 S499 1.14.99.1 Q05769 24060487 ANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQ 4llz B 2.35 BS01 LUR B 1 Y348 V349 L352 Y385 W387 M522 G526 A527 S530 Y317 V318 L321 Y354 W356 M491 G495 A496 S499 1.14.99.1 Q05769 24060487 ANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNV 4m0e A 2.00 BS01 1YL A 1 Y72 Y124 W286 S293 V294 F295 F297 Y337 F338 Y341 Y69 Y121 W278 S285 V286 F287 F289 Y329 F330 Y333 3.1.1.7 P22303 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 4m0f A 2.30 BS01 1YK A 1 Y72 W86 G121 Y124 S203 W286 S293 F297 Y337 F338 Y341 H447 Y69 W83 G118 Y121 S200 W277 S284 F288 Y328 F329 Y332 H438 3.1.1.7 P22303 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 4m69 A 2.50 BS01 ANP A 1 V28 G29 K30 G31 G32 F33 V36 A49 K51 T95 R96 F97 M98 S102 D143 K145 S147 N148 L150 D161 V17 G18 K19 G20 G21 F22 V25 A38 K40 T84 R85 F86 M87 S91 D132 K134 S136 N137 L139 D150 2.7.11.1 Q9QZL0 SAVPLVSREELKKLEFVGKGGFGVVFRAHHRTWNHDVAVKIVNSKKISWEVKAMVNLRNENVLLLLGVTEDLQWDFVSGQALVTRFMENGSLAGLLQPECPRPWPLLCRLLQEVVLGMCYLHSLDPPLLHRDLKPSNILLDPELHAKLADFGLSTFQDSGGTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGREAELVDKTSLIRETVCDRQSRPPLTELPPGSPETPGLEKLKELMIHCWGSQSENRPSFQDCEPKTNEVYNLVKDKVDAAVSEVKHYLSQ 4m69 A 2.50 BS02 MG A 1 N148 D161 N137 D150 2.7.11.1 Q9QZL0 SAVPLVSREELKKLEFVGKGGFGVVFRAHHRTWNHDVAVKIVNSKKISWEVKAMVNLRNENVLLLLGVTEDLQWDFVSGQALVTRFMENGSLAGLLQPECPRPWPLLCRLLQEVVLGMCYLHSLDPPLLHRDLKPSNILLDPELHAKLADFGLSTFQDSGGTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGREAELVDKTSLIRETVCDRQSRPPLTELPPGSPETPGLEKLKELMIHCWGSQSENRPSFQDCEPKTNEVYNLVKDKVDAAVSEVKHYLSQ 4m7e A 3.60 BS01 BLD A 1 I563 W564 Y597 K601 Y642 T646 S647 P648 M657 F681 I682 N705 I706 I530 W531 Y564 K568 Y609 T613 S614 P615 M624 F648 I649 N672 I673 2.7.10.1,2.7.11.1 O22476 REIHQLISFKDVLPDKNLLPDWSSNKNPCTFDGVTCRDDKVTSIDLSSKPLNVGFSAVSSSLLSLTGLESLFLSNSHINGSVSGFKCSASLTSLDLSRNSLSGPVTTLTSLGSCSGLKFLNVSSNTLDFPGKVSGGLKLNSLEVLDLSANSISGANVVGWVLSDGCGELKHLAISGNKISGDVDVSRCVNLEFLDVSSNNFSTGIPFLGDCSALQHLDISGNKLSGDFSRAISTCTELKLLNISSNQFVGPIPPLPLKSLQYLSLAENKFTGEIPDFLSGACDTLTGLDLSGNHFYGAVPPFFGSCSLLESLALSSNNFSGELPMDTLLKMRGLKVLDLSFNEFSGELPESLTNLSASLLTLDLSSNNFSGPILPNLCQNPKNTLQELYLQNNGFTGKIPPTLSNCSELVSLHLSFNYLSGTIPSSLGSLSKLRDLKLWLNMLEGEIPQELMYVKTLETLILDFNDLTGEIPSGLSNCTNLNWISLSNNRLTGEIPKWIGRLENLAILKLSNNSFSGNIPAELGDCRSLIWLDLNTNLFNGTIPAAMFKQSGKIAANFIAGKRYVYIKNDGMKKECHGAGNLLEFQGIRSEQLNRLSTRNPCNITSRVYGGHTSPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNILDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSGPIPEMGQFETFPPAKFLNNPGLCGYP 4m7e D 3.60 BS01 BLD B 1 W59 F60 H61 V62 W34 F35 H36 V37 2.7.10.1,2.7.11.1 Q94F62 NAEGDALSALKNSLADPNKVLQSWDATLVTPCTWFHVTCNSDNSVTRVDLGNANLSGQLVMQLGQLPNLQYLELYSNNITGTIPEQLGNLTELVSLDLYLNNLSGPIPSTLGRLKKLRFLRLNNNSLSGEIPRSLTAVLTLQVLDLSNNPLTGDIPVNGSFSLFTPISFANTKLT 4m9h A 2.39 BS04 TTP A 1 R149 S180 R183 G189 R139 S170 R173 G179 2.7.7.7,4.2.99.- P06746 LNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINKYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRS 4m9j A 2.04 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 K295 Y296 H25 S215 K216 G217 E218 T219 K220 Y252 K272 Y273 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHAFTINKYTIRPLVTGVAGEPLPVDSEKDIFDYYREPKDRSE 4m9j A 2.04 BS05 DUP A 1 G179 S180 R183 S188 G189 D190 D192 Y271 F272 G274 G170 S171 R174 S179 G180 D181 D183 Y252 F253 G255 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHAFTINKYTIRPLVTGVAGEPLPVDSEKDIFDYYREPKDRSE 4m9n A 2.27 BS05 DTP A 1 R149 S180 R183 G189 D190 D192 Y271 F272 T273 G274 D276 N279 R140 S171 R174 G180 D181 D183 Y253 F254 T255 G256 D258 N261 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHTINKYTIRPLGEPLPVDSEKDIFDYREPKDRSE 4mb9 A 1.85 BS01 28F A 1 I48 N51 E55 V76 D78 R81 G82 M83 P84 G117 L119 R140 T172 I32 N35 E39 V60 D62 R65 G66 M67 P68 G89 L91 R112 T144 5.99.1.- G6TGY9 24088190 QVLEGLDAVRKRPGMYIGSTDGAGLHHLVWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTILHAGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLKKIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDEAIEFHYEN 4mbc A 1.75 BS01 28G A 1 I48 N51 A52 E55 V76 D78 R81 G82 M83 P84 R140 T172 V174 I32 N35 A36 E39 V60 D62 R65 G66 M67 P68 R107 T139 V141 5.99.1.- G6TGY9 24088190 QVLEGLDAVRKRPGMYIGSTDGAGLHHLVWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTILHAVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLKKIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDEAIEFHYEN 4mdt A 2.59 BS02 24G A 1 L18 L62 K143 I159 D160 F161 F192 M195 I198 C207 G210 S211 V217 K239 K262 G264 H265 L18 L62 K143 I159 D160 F161 F192 M195 I198 C207 G210 S211 V217 K239 K262 G264 H265 3.5.1.- K0BGQ2 MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNSAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP 4mdt B 2.59 BS02 24G B 1 L18 L62 K143 I159 D160 F161 F192 F194 I198 C207 G210 S211 A215 V217 K239 K262 G264 H265 L18 L62 K143 I159 D160 F161 F192 F194 I198 C207 G210 S211 A215 V217 K239 K262 G264 H265 3.5.1.- K0BGQ2 MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNSAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP 4mdt C 2.59 BS02 24G C 1 L18 T60 L62 I159 F161 F192 I198 C207 G210 S211 F212 A215 V217 K239 K262 G264 H265 L18 T60 L62 I159 F161 F191 I197 C206 G209 S210 F211 A214 V216 K238 K261 G263 H264 3.5.1.- K0BGQ2 MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNSAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP 4mdt D 2.59 BS02 24G D 1 L18 L62 K143 I159 D160 F161 F192 F194 M195 I198 G210 S211 C214 A215 V217 K239 K262 G264 H265 L15 L59 K140 I156 D157 F158 F189 F191 M192 I195 G207 S208 C211 A212 V214 K236 K259 G261 H262 3.5.1.- K0BGQ2 QRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNSAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLA 4mgg A 2.20 BS01 MG A 1 D193 E218 D241 N263 K265 D195 E220 D243 N265 K267 A0NXQ8 SHMKITAINVFQVDLPLREGRYSWSNGNFVEVFDSTVVEIETDEGLKGYAECCPLGSAYLPSYALGVRSGLQELAPHLIGKDPLNIGEINRVMDAALRGHPYAKAPIDIACWDLLGKATGQPLYTLLGGAAQDDVALYRAISQEAPEIMAKKIEGYAAEGYTKFQLKVGGDANDDINRIHATRSVLKKSDLLVADANTGWTRHEAARVVGAVSSLDVYIEQPCLTYEESVSIRRRTALPFVLDEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIVTAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKRVNGRMTTSDLPGLGITPIFDVLGEPVARYS 4mgg B 2.20 BS01 MG B 1 D193 E218 D241 N263 D187 E212 D235 N257 A0NXQ8 MKITAINVFQVDLPLREGRYSWSNGNFVEVFDSTVVEIETDEGLKGYAECCPLSYALGVRSGLQELAPHLIGKDPLNIGEINRVMDAALRGHPYAKAPIDIACWDLLGKATGQPLYTLLGGAAQDDVALYRAISQEAPEIMAKKIEGYAAEGYTKFQLKVGGDANDDINRIHATRSVLKKSDLLVADANTGWTRHEAARVVGAVSSLDVYIEQPCLTYEESVSIRRRTALPFVLDEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIVTAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKRVNGRMTTSDLPGLGITPIFDVLGEPVARYS 4mgg D 2.20 BS01 MG D 1 Q163 D193 E218 D241 Q157 D187 E212 D235 A0NXQ8 HMKITAINVFQVDLPLREGRYSWSNGNFVEVFDSTVVEIETDEGLKGYAECCPLYALGVRSGLQELAPHLIGKDPLNIGEINRVMDAALRGHPYAKAPIDIACWDLLGKATGQPLYTLLGGAAQDDVALYRAISQEAPEIMAKKIEGYAAEGYTKFQLKVGGDANDDINRIHATRSVLKKSDLLVADANTGWTRHEAARVVGAVSSLDVYIEQPCLTYEESVSIRRRTALPFVLDEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIVTAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKRVNGRMTTSDLPGLGITPIFDVLGEPVARYS 4mgg E 2.20 BS01 MG E 1 N24 G197 N25 G191 A0NXQ8 HMKITAINVFQVDLPLREGRYSWSNGNFVEVFDSTVVEIETDEGLKGYAECCPLYALGVRSGLQELAPHLIGKDPLNIGEINRVMDAALRGHPYAKAPIDIACWDLLGKATGQPLYTLLGGAAQDDVALYRAISQEAPEIMAKKIEGYAAEGYTKFQLKVGGDANDDINRIHATRSVLKKSDLLVADANTGWTRHEAARVVGAVSSLDVYIEQPCLTYEESVSIRRRTALPFVLDEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIVTAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKRVNGRMTTSDLPGLGITPIFDVLGEPVARYS 4mgg F 2.20 BS01 MG F 1 D193 E218 D241 D188 E213 D236 A0NXQ8 HMKITAINVFQVDLPLREGRYSWSNGNFVEVFDSTVVEIETDEGLKGYAECCPLSYALGVRSGLQELAPHLIGKDPLNIGEINRVMDAALRGHPYAKAPIDIACWDLLGKATGQPLYTLLGGAAQDDVALYRAISQEAPEIMAKKIEGYAAEGYTKFQLKVGGDANDDINRIHATRSVLKKSDLLVADANTGWTRHEAARVVGAVSSLDVYIEQPCLTYEESVSIRRRTALPFVLDEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIVTAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKRVNGRMTTSDLPGLGITPIFDVLGEPVARYS 4mh5 A 1.65 BS01 GGL A 1 Y63 P90 L91 T92 R97 G142 A143 T144 E191 Y61 P88 L89 T90 R95 G140 A141 T142 E189 P42264 21907808 GTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCP 4mix A 1.80 BS01 CA A 1 D2276 D2278 D146 D148 2.4.1.- C7BKP9 DDIRKYIARKSAIKIFNQSINYSATKWPPEPIDKNIHMIWIGTKNISEKNIKLSIDTAKKNPDYNTSIIYDSGISGHEGAKKFMLEKFQDSNVNIIDFRKKSYFSQLKQEPSFAYYEQVIAENKYAQASDILRLLVLKYEGGIYKDIDDIQVKGFGSLTFPKGIGVMREYTAFPNTPIAVTKNNPIINKTLDLAVSNYQRGEKNVLKLAGPDVFTQALYQEIPGLDSKVLNAQLYQLELAKRQALGVPLEQLTSAEKEKINRPYQSIRGLSGYVEN 4mix A 1.80 BS02 UD1 A 1 I2169 W2170 I2171 Y2255 A2256 S2259 D2260 R2263 D2276 I2277 D2278 Y2300 N2312 P2348 I39 W40 I41 Y125 A126 S129 D130 R133 D146 I147 D148 Y170 N175 P211 2.4.1.- C7BKP9 DDIRKYIARKSAIKIFNQSINYSATKWPPEPIDKNIHMIWIGTKNISEKNIKLSIDTAKKNPDYNTSIIYDSGISGHEGAKKFMLEKFQDSNVNIIDFRKKSYFSQLKQEPSFAYYEQVIAENKYAQASDILRLLVLKYEGGIYKDIDDIQVKGFGSLTFPKGIGVMREYTAFPNTPIAVTKNNPIINKTLDLAVSNYQRGEKNVLKLAGPDVFTQALYQEIPGLDSKVLNAQLYQLELAKRQALGVPLEQLTSAEKEKINRPYQSIRGLSGYVEN 4mkv A 2.15 BS01 RUB A 1 K175 K177 D203 E204 R295 H327 K334 L335 S379 G380 G381 G403 G404 K164 K166 D192 E193 R284 H316 K323 L324 S368 G369 G370 G392 G393 4.1.1.39 P04717 GFKAGVKDYKLTYYTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYEIEPVPGEDNQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPYAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMLKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIKKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNAIIREACKWSPELAAACEVWKEIKFEF 4mkv B 2.15 BS02 A8S B 1 L37 Y85 E86 Y100 R139 K356 Y363 F364 T365 L26 Y74 E75 Y89 R128 K345 Y352 F353 T354 4.1.1.39 P04717 GFKAGVKDYKLTYYTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYEIEPVPGEDNQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPYAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMLKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIKKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNAIIREACKWSPELAAACEVWKEIKFEF 4mkv D 2.15 BS01 RUB D 1 K175 E204 H294 R295 H327 K334 L335 S379 G380 G381 G403 G404 K164 E193 H283 R284 H316 K323 L324 S368 G369 G370 G392 G393 4.1.1.39 P04717 GFKAGVKDYKLTYYTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYEIEPVPGEDNQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPYAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMLKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIKKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNAIIREACKWSPELAAACEVWKEIKFEF 4mlp C 1.94 BS01 2CX C 1 Q307 W310 H373 R376 H377 F399 V410 N411 S414 W415 W417 Q287 W290 H353 R356 H357 F379 V390 N391 S394 W395 W397 Q9R194 24080726 ASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRY 4mlp D 1.94 BS01 2CX D 1 Q307 W310 H373 R376 H377 F399 L403 V410 N411 S414 W415 W417 L418 Q287 W290 H353 R356 H357 F379 L383 V390 N391 S394 W395 W397 L398 Q9R194 24080726 ASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRY 4mm4 A 2.89 BS01 8PR A 1 Y21 A22 D24 P101 A105 Y107 Y108 F253 S254 F259 S355 S356 G359 M360 D404 T408 Y17 A18 D20 P97 A101 Y103 Y104 F246 S247 F252 S348 S349 G352 M353 D397 T401 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYTHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mm5 A 3.20 BS01 SRE A 1 Y21 D24 P101 A105 Y108 F253 G256 F259 S355 G359 Y17 D20 P97 A101 Y104 F246 G249 F252 S348 G352 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYTHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mm6 A 3.10 BS01 29E A 1 Y21 A22 D24 P101 V104 A105 Y107 Y108 F253 S254 F259 V261 S356 G359 T408 Y17 A18 D20 P97 V100 A101 Y103 Y104 F246 S247 F252 V254 S349 G352 T401 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mm7 A 2.85 BS01 29J A 1 Y21 A22 D24 V104 Y107 Y108 F253 F259 S355 G359 D404 T408 Y17 A18 D20 V100 Y103 Y104 F246 F252 S348 G352 D397 T401 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPTHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mm8 A 3.31 BS01 RFX A 1 Y21 A22 D24 P101 V104 A105 Y108 F253 S254 G256 F259 S356 G359 D404 T408 Y17 A18 D20 P97 V100 A101 Y104 F246 S247 G249 F252 S349 G352 D397 T401 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYITHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mm9 A 2.90 BS01 FVX A 1 Y21 A22 D24 P101 V104 A105 Y107 Y108 F253 S254 G256 F259 S355 S356 G359 D404 Y17 A18 D20 P97 V100 A101 Y103 Y104 F246 S247 G249 F252 S348 S349 G352 D397 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mma A 3.30 BS01 CXX A 1 Y21 D24 P101 V104 A105 Y108 F253 F259 S355 S356 G359 T408 Y17 D20 P97 V100 A101 Y104 F246 F252 S348 S349 G352 T401 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVASYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGVLITFASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQGMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWATGIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mmc A 2.30 BS01 29J A 1 Y21 A22 D24 V104 Y108 F253 G256 F259 S355 G359 D404 Y17 A18 D20 V100 Y104 F246 G249 F252 S348 G352 D397 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGAIITFASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mmc A 2.30 BS02 29J A 2 F320 L400 D401 D404 T409 F313 L393 D394 D397 T402 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGAIITFASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mmd A 2.30 BS01 29E A 1 Y21 A22 D24 P101 V104 A105 Y108 F253 S254 L255 G256 F259 S356 G359 Y17 A18 D20 P97 V100 A101 Y104 F246 S247 L248 G249 F252 S349 G352 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGAIITFASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mme A 2.50 BS01 29Q A 1 Y21 A22 D24 P101 V104 A105 Y108 F253 G256 F259 S355 S356 G359 Y17 A18 D20 P97 V100 A101 Y104 F246 G249 F252 S348 S349 G352 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGAIITFASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mmf A 2.70 BS01 29Q A 1 Y21 A22 D24 P101 V104 A105 Y108 F253 S254 G256 F259 G359 Y17 A18 D20 P97 V100 A101 Y104 F246 S247 G249 F252 G352 O67854 REHWATRLGLILAMAGYAVDLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFSLGLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAGMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHE 4mvt A 2.30 BS01 ZN A 1 C343 H345 C366 C369 C190 H192 C213 C216 6.3.2.- Q9Y6X2 DVTMKPLPFYEVYGELIRPTTLFEEAHFTFALTPQQVQQILTSRDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYKRPSRPINITPLARLSATVPNTIVVNWSSRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSCSDCDEIQFMEDGSWCPM 4my4 A 2.00 BS01 MN A 1 K330 D397 H401 H456 K328 D395 H399 H454 5.4.2.1 Q2G029 KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH 4my4 A 2.00 BS02 MN A 2 D12 S62 K330 D438 H439 D10 S60 K328 D436 H437 5.4.2.1 Q2G029 KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH 4mzw A 1.95 BS01 GDS A 1 F19 N23 T49 N51 I79 Q84 K97 I98 P99 E114 S115 P152 G155 G156 W212 F27 N31 T57 N59 I87 Q92 K105 I106 P107 E122 S123 P160 G163 G164 W220 A3CNR0 SGVDLGTENTYQLPKVWSAADSDQGKFSGINQPTAGVRFEQKLPVGKEPFQLYSLGTPNGVKVTIMLEELLAAGVTEATYDLYKISIMDGDQFGSDFVKINPNSKIPALLDQSGHKPIPVFESANILLYLAEKFGKLIPSDLAGRTEVLNWLFWQTGAAPFLGGGFGHFFNYAPEKLEYPINRFTMEAKRQLDLLDKELAKKAYIAGEDYSIADIAIWSWYGQLVQDKLYPGAAEFLDAASYKHLSAWAEKIAARPAVQRGLAAEYQEIK 4mzw B 1.95 BS01 GDS B 1 F19 I22 N23 T49 N51 I79 Q84 K97 I98 E114 S115 P152 G155 G156 W212 F18 I21 N22 T48 N50 I78 Q83 K96 I97 E113 S114 P151 G154 G155 W211 A3CNR0 TYQLPKVWSAADSDQGKFSGINQPTAGVRFEQKLPVGKEPFQLYSLGTPNGVKVTIMLEELLAAGVTEATYDLYKISIMDGDQFGSDFVKINPNSKIPALLDQSGHKPIPVFESANILLYLAEKFGKLIPSDLAGRTEVLNWLFWQTGAAPFLGGGFGHFFNYAPEKLEYPINRFTMEAKRQLDLLDKELAKKAYIAGEDYSIADIAIWSWYGQLVQDKLYPGAAEFLDAASYKHLSAWAEKIAARPAVQRGLAAEYQEIK 4n15 A 1.65 BS01 BDP A 1 V34 H35 E73 R89 N91 R149 R169 Q171 F192 N209 N210 S213 E236 V8 H9 E47 R63 N65 R123 R143 Q145 F166 N183 N184 S187 E210 Q0B2F6 RVFRSADVHGDSFPTNMAVKFMGDELSKLTGGKDSIKVFGNSALGSEKDTVDQVRIGAIDMARVNGASFNEIVPESLIPSFPFLFRDVDHFRKAMYGPAGQKILDAFAAKGMIALTFYESGARSIYAKRPVRTPADMKGLKVRVQPSDLMVDEIRAMGGTPTPMPFAEVYTGLKTGLVDAAENNLPSYEETKHFEVAPDYSETQHAMTPEVLVFSKKIWDTLSPQEQAAIRKAAADSVPYYQKLWTAREASAQQAVTKGGANILPAAQVDRAAFVKAMQPLWTKYEKTPQMKQIVDEIEAT 4n17 A 1.50 BS01 GTR A 1 H35 E73 R89 N91 R149 R169 Q171 F192 N209 S213 E236 H9 E47 R63 N65 R123 R143 Q145 F166 N183 S187 E210 Q0B2F6 RVFRSADVHGDSFPTNMAVKFMGDELSKLTGGKDSIKVFGNSALGSEKDTVDQVRIGAIDMARVNGASFNEIVPESLIPSFPFLFRDVDHFRKAMYGPAGQKILDAFAAKGMIALTFYESGARSIYAKRPVRTPADMKGLKVRVQPSDLMVDEIRAMGGTPTPMPFAEVYTGLKTGLVDAAENNLPSYEETKHFEVAPDYSETQHAMTPEVLVFSKKIWDTLSPQEQAAIRKAAADSVPYYQKLWTAREASAQQAVTKGGANILPAAQVDRAAFVKAMQPLWTKYEKTPQMKQIVDEIEAT 4n3o B 2.40 BS01 CA B 1 S83 E150 D151 S86 E153 D154 Q0P8I9 SNAMKTIRTQTPLRLGLAGGGTDINLYCDKYTGYVLNATISLYIHCTLIKREDGKIIFDSPDTNSYCEYESKEFLGNDGKLDIFKSIYNRIVKDFTKKPLSFSLHTYSDVPSGSGLGGSSTLVVGVIKAFAEWLNLPLGEYEIAKLAYEIEREDLGIVGGAQDQYAATFGGFNFMEFYNNKRVIVNPLRIKNWIASELEARTVLYFTNITSLEAMHAIKQDAIKMKEALFRADFGTLAQILGKSWRNDELERIYKLAIDNGAYSGKTSGAGAGGFMFFFVDPTKKYNLIKALRKEQGYVQDFSFTKEGVKSWRI