2lvz A BS01 LVZ A 1 R7 Q14 R34 V127 H128 R7 Q14 R34 V127 H128 3.1.27.- P12724 23025322 RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 2lvz A BS02 SGN A 1 K38 N39 Q40 K38 N39 Q40 3.1.27.- P12724 23025322 RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCRYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 2ma6 A BS01 ZN A 1 C11 C14 C31 C34 C11 C14 C31 C34 6.3.2.- Q5XPI4 SHMPTSEEDLCPICYAHPISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKG 2ma6 A BS02 ZN A 2 C26 H28 C45 C48 C26 H28 C45 C48 6.3.2.- Q5XPI4 SHMPTSEEDLCPICYAHPISAVFQPCGHKSCKACINQHLMNNKDCFFCKTTIVSVEDWEKG 2ypa A 2.80 BS01 NUC E 1 R189 N193 E196 R197 N204 S224 K225 R8 N12 E15 R16 N23 S43 K44 P17542 23831025 PHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEE 2ypa A 2.80 BS02 NUC F 1 R195 E196 R199 R14 E15 R18 P17542 23831025 PHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEE 2ypa B 2.80 BS01 NUC E 1 E555 R558 E17 R20 P15923 23831025 EKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPK 2ypa B 2.80 BS02 NUC F 1 N552 E555 R556 T584 K585 N14 E17 R18 T46 K47 P15923 23831025 EKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPK 2ypb A 2.87 BS01 NUC E 1 R189 N193 E196 R197 Q201 N204 S224 K225 R9 N13 E16 R17 Q21 N24 S44 K45 P17542 23831025 GPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQE 2ypb B 2.87 BS02 NUC F 1 R548 N552 E555 R556 N563 T584 K585 R13 N17 E20 R21 N28 T49 K50 P15923 23831025 SLEEKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLN 3j41 E 25.00 BS02 CA E 2 D58 N60 T62 D64 D53 N55 T57 D59 P62158 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 3vw4 A 2.70 BS01 NUC C 1 K185 R189 R252 G253 K255 G256 K259 S260 K261 R262 R270 I280 S281 A283 T284 R287 K16 R20 R83 G84 K86 G87 K90 S91 K92 R93 R101 I111 S112 A114 T115 R118 Q06B24 HHHHHRNYHLFEKVRKWAYRAIRQGWPVFSQWLDAVIQRVEMYNASLPVPLSPAECRAIGKSIAKYTHRKFSPEGFSAVQAARGRKGGTKSKRAAVPTSARSLKPWEALGISRATYYRKLKC 3vw4 A 2.70 BS02 NUC D 1 N176 F180 R184 Y188 R189 R192 I228 S231 I232 Y235 K239 F240 S241 G244 F245 S246 V248 Q249 A250 R252 G253 R254 G257 T258 S260 K261 R262 A263 A264 V265 S268 A269 R270 S271 R282 Y286 R287 K290 N7 F11 R15 Y19 R20 R23 I59 S62 I63 Y66 K70 F71 S72 G75 F76 S77 V79 Q80 A81 R83 G84 R85 G88 T89 S91 K92 R93 A94 A95 V96 S99 A100 R101 S102 R113 Y117 R118 K121 Q06B24 HHHHHRNYHLFEKVRKWAYRAIRQGWPVFSQWLDAVIQRVEMYNASLPVPLSPAECRAIGKSIAKYTHRKFSPEGFSAVQAARGRKGGTKSKRAAVPTSARSLKPWEALGISRATYYRKLKC 3vw4 B 2.70 BS01 NUC E 1 A247 V248 A251 R252 G253 K255 G256 S260 K261 R262 I280 S281 T284 R287 A77 V78 A81 R82 G83 K85 G86 S90 K91 R92 I110 S111 T114 R117 Q06B24 HHHHRNYHLFEKVRKWAYRAIRQGWPVFSQWLDAVIQRVEMYNASLPVPLSPAECRAIGKSIAKYTHRKFSPEGFSAVQAARGRKGGTKSKRAAVPTSARSLKPWEALGISRATYYRKLK 3w9z A 2.10 BS01 FMN A 1 A6 P7 M8 E9 V11 F33 Q68 N95 C98 K139 H168 Y176 N200 G201 E202 G224 R225 A6 P7 M8 E9 V11 F33 Q68 N95 C98 K126 H155 Y163 N187 G188 E189 G211 R212 P33371 MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEHVARIKQWLSYLRKEYDEATELFQHVRVSPDIARAIQAIDIEK 3wav A 1.80 BS04 DWV A 1 S169 F210 L213 A217 L243 W260 F273 F274 W275 A304 Y306 S119 F160 L163 A167 L193 W210 F223 F224 W225 A254 Y256 3.1.4.39 Q9R1E6 23688339 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKNKLEELNKRLHTKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 3waw A 1.95 BS04 DWW A 1 I167 S169 F210 L213 L243 F273 F274 W275 V277 A304 Y306 I117 S119 F160 L163 L193 F223 F224 W225 V227 A254 Y256 3.1.4.39 Q9R1E6 23688339 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 3wax A 1.90 BS04 DWX A 1 D171 T209 F210 L213 A217 N230 L243 F273 F274 W275 Y306 D311 H359 H474 D121 T159 F160 L163 A167 N180 L193 F223 F224 W225 Y256 D261 H309 H414 3.1.4.39 Q9R1E6 23688339 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDLEELNHTKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 3way A 1.75 BS04 DWY A 1 S169 D171 T209 L213 N230 L243 F273 F274 W275 Y306 D311 H359 H474 S119 D121 T159 L163 N180 L193 F223 F224 W225 Y256 D261 H309 H414 3.1.4.39 Q9R1E6 23688339 WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDLEEHTKGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE 4b1u B 2.00 BS01 LAB B 1 G15 L16 P32 I34 Q59 Y69 D157 R183 T186 R206 E207 R210 G11 L12 P28 I30 Q40 Y50 D138 R164 T167 R187 E188 R191 P68134 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 4b1u B 2.00 BS02 ATP B 1 G13 S14 G15 L16 K18 G156 D157 G158 V159 G182 R210 K213 E214 G301 G302 M305 Y306 K336 G9 S10 G11 L12 K14 G137 D138 G139 V140 G163 R191 K194 E195 G275 G276 M279 Y280 K310 P68134 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 4b1u M 2.00 BS01 CA M 1 F133 K134 H135 T136 F1 K2 H3 T4 Q2M3X8 FKHTSAALERKISMRQSREELIKRGVLKEI 4b1w B 1.95 BS01 III M 1 Y143 G146 T148 Y166 E167 G168 Y169 H173 I345 L346 L349 Y130 G133 T135 Y153 E154 G155 Y156 H160 I332 L333 L336 P68135 TALVCDNGSGLVKAGFAGDDAPRAVFPSIVARPRHQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4b1x B 1.80 BS01 III M 1 L110 Y143 A144 G146 T148 Y166 E167 G168 Y169 A170 P172 H173 I175 I345 L346 L349 T351 F375 L92 Y125 A126 G128 T130 Y148 E149 G150 Y151 A152 P154 H155 I157 I327 L328 L331 T333 F357 P68135 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 4b7b A 2.50 BS02 CO A 1 C87 D91 K146 C72 D76 K127 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGEREYTWEEVPLDGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENININQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 4b7b A 2.50 BS03 CO A 2 E145 K207 E126 K187 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGEREYTWEEVPLDGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENININQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 4b7b A 2.50 BS04 CO A 3 E145 D149 E126 D130 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGEREYTWEEVPLDGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENININQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 4b7b A 2.50 BS05 CO A 4 I163 E166 S291 I144 E147 S257 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGEREYTWEEVPLDGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENININQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 4b7b A 2.50 BS06 CA A 1 R26 P27 F28 P338 R11 P12 F13 P304 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGEREYTWEEVPLDGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENININQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 4bw5 A 3.40 BS01 K A 1 G174 Y175 G176 G283 F284 G285 G98 Y99 G100 G200 F201 G202 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLS 4bw5 A 3.40 BS02 K A 2 I173 G174 Y175 V282 G283 F284 I97 G98 Y99 V199 G200 F201 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLS 4bw5 A 3.40 BS03 K A 3 T172 I173 G174 T281 V282 G283 T96 I97 G98 T198 V199 G200 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLS 4bw5 A 3.40 BS04 K A 4 T172 T280 T281 V282 T96 T197 T198 V199 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLS 4bw5 B 3.40 BS04 K A 7 T172 I173 T281 T94 I95 T203 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSK 4bw5 C 3.40 BS01 K C 1 G174 Y175 G176 G283 F284 G285 G98 Y99 G100 G192 F193 G194 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIAIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNEWYKPLVWFWILVGLAYFAAVLSMIGDWLRVL 4bw5 C 3.40 BS02 K C 2 I173 G174 Y175 V282 G283 F284 I97 G98 Y99 V191 G192 F193 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIAIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNEWYKPLVWFWILVGLAYFAAVLSMIGDWLRVL 4bw5 C 3.40 BS03 K C 3 T172 I173 G174 T281 V282 G283 T96 I97 G98 T190 V191 G192 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIAIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNEWYKPLVWFWILVGLAYFAAVLSMIGDWLRVL 4bw5 C 3.40 BS04 K C 4 T172 T281 V282 T96 T190 V191 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIAIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNEWYKPLVWFWILVGLAYFAAVLSMIGDWLRVL 4bw5 D 3.40 BS04 K C 7 T172 I173 T281 V282 T93 I94 T202 V203 P57789 KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPISHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKK 4bw9 A 2.35 BS02 ANP A 1 R330 E332 H338 L339 F342 M344 E396 L397 S398 S399 G423 R426 R141 E143 H149 L150 F153 M155 E207 L208 S209 S210 G234 R237 6.1.1.26 Q8PWY1 APALTKSQTDRLEVLLNPKDEISGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTLDVMHGDLELSSAVVGPRPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNL 4bwa A 2.45 BS02 N0B A 1 A302 G306 L309 R330 E332 H338 L339 F342 M344 N346 C348 E396 L397 S398 S399 W417 G419 G421 G423 R426 A114 G118 L121 R142 E144 H150 L151 F154 M156 N158 C160 E202 L203 S204 S205 W223 G225 G227 G229 R232 6.1.1.26 Q8PWY1 APALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDLSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDDTLDVMHGDLELSSAVVGPRPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNL 4bxn A 2.79 BS01 ADP A 1 G108 G110 K111 T112 F113 S232 G91 G93 K94 T95 F96 S215 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE 4bxn A 2.79 BS02 MJQ A 1 E116 G117 E118 R119 D130 A133 P137 Y211 L214 E215 K216 G217 A218 A219 R221 E99 G100 E101 R102 D113 A116 P120 Y194 L197 E198 K199 G200 A201 A202 R204 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE 4bxn B 2.79 BS01 ADP B 1 R24 R26 P27 G105 Q106 G108 T109 G110 K111 T112 F113 T114 R9 R11 P12 G86 Q87 G89 T90 G91 K92 T93 F94 T95 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTDKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE 4bxn B 2.79 BS02 MJQ B 1 E116 G117 I136 P137 L160 Y211 L214 E215 G217 A218 E97 G98 I117 P118 L141 Y192 L195 E196 G198 A199 P52732 23875972 GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTDKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE 4bxs V 3.32 BS01 CA V 1 K94 S99 E109 R110 D112 D113 K83 S88 E98 R99 D101 D102 Q7SZN0 23869089 AQLREYHIAAQLEDWDYNPQLTFKKIVYREYELDFKQEKPRDALSGLLGPTLRGEVGDSLIIYFKNFATQPVSIHPQSAVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEIGPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNANGSQKFFNREYVLMFSVFDESKNWYRKPSLQYTINGFANGTLPDVQACAYDHISWHLIGMSSSPEIFSVHFNGQTLEQNHYKVSTINLVGGASVTADMSVSRTGKWLISSLVAKHLQAGMYGYLNIKDCGNPDMKIKNWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKYKKAVFRQYEDGNFTKPTYAIWPKERGILGPVIKAKVRDTVTIVFKNLASRPYSIYVHGVSVSKDAEGAIYPSDPTHGKAVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPLLVCKHKALSGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSAVKKDDPKFYKSNVMYTLNGYASDRTEVLRFHQSEVVQWHLTSVGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLSSWGSCEMSNGMRLRFLDANYDDEDEGNEEEEEDDGDIFADIFIPSEGNKRRYYIAAEEVLWDYSPKTTFKKAIFRSYLDDTFQTPSTGGEYEKHLGILGPIIRAEVDDVIEIQFKNLASRPYSLHAHGLLYEKSSEGRSYDDKSPELFKKDDAIMPNGTYTYVWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDKYNRTIDIREFVLFFMVFDEEKSWYFPCSLHTFPAINGIPYQLQGLTMYKDENVHWHLLNMGGPKDIHVVNFHGQTFTEEGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQALFTVIDKDCKLPMGLASGIIQDSQISASGHVGYWEPKLARLNNTGKYNAWSIIKKEHEHPWIQIDLQRQVVITGIQTQGTVQLLQHSYTVEYFVTYSEDGQNWITFKGQMHFEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNRPTFRIELLGCEVEGCSVPLGMESGAIKNKEITASSYKKTWWSSWEPFLARLNLEGGTNAWQPEVNNKDQWLQIDLQHLTKITSIITQGATSMTTSMYVKTFSIHYTDDNSTWKPYLDVRTSMEKVFTGNINSDGHVKHFFKPPILSRFIRIIPKTWNQYIALRIELFGCEV 4bxs V 3.32 BS02 CA V 2 K890 E893 R895 F905 D908 D909 K742 E745 R747 F757 D760 D761 Q7SZN0 23869089 AQLREYHIAAQLEDWDYNPQLTFKKIVYREYELDFKQEKPRDALSGLLGPTLRGEVGDSLIIYFKNFATQPVSIHPQSAVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEIGPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNANGSQKFFNREYVLMFSVFDESKNWYRKPSLQYTINGFANGTLPDVQACAYDHISWHLIGMSSSPEIFSVHFNGQTLEQNHYKVSTINLVGGASVTADMSVSRTGKWLISSLVAKHLQAGMYGYLNIKDCGNPDMKIKNWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKYKKAVFRQYEDGNFTKPTYAIWPKERGILGPVIKAKVRDTVTIVFKNLASRPYSIYVHGVSVSKDAEGAIYPSDPTHGKAVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPLLVCKHKALSGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSAVKKDDPKFYKSNVMYTLNGYASDRTEVLRFHQSEVVQWHLTSVGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLSSWGSCEMSNGMRLRFLDANYDDEDEGNEEEEEDDGDIFADIFIPSEGNKRRYYIAAEEVLWDYSPKTTFKKAIFRSYLDDTFQTPSTGGEYEKHLGILGPIIRAEVDDVIEIQFKNLASRPYSLHAHGLLYEKSSEGRSYDDKSPELFKKDDAIMPNGTYTYVWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDKYNRTIDIREFVLFFMVFDEEKSWYFPCSLHTFPAINGIPYQLQGLTMYKDENVHWHLLNMGGPKDIHVVNFHGQTFTEEGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQALFTVIDKDCKLPMGLASGIIQDSQISASGHVGYWEPKLARLNNTGKYNAWSIIKKEHEHPWIQIDLQRQVVITGIQTQGTVQLLQHSYTVEYFVTYSEDGQNWITFKGQMHFEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNRPTFRIELLGCEVEGCSVPLGMESGAIKNKEITASSYKKTWWSSWEPFLARLNLEGGTNAWQPEVNNKDQWLQIDLQHLTKITSIITQGATSMTTSMYVKTFSIHYTDDNSTWKPYLDVRTSMEKVFTGNINSDGHVKHFFKPPILSRFIRIIPKTWNQYIALRIELFGCEV 4bxs V 3.32 BS03 CU V 1 H148 H1055 E1095 H137 H893 E933 Q7SZN0 23869089 AQLREYHIAAQLEDWDYNPQLTFKKIVYREYELDFKQEKPRDALSGLLGPTLRGEVGDSLIIYFKNFATQPVSIHPQSAVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEIGPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNANGSQKFFNREYVLMFSVFDESKNWYRKPSLQYTINGFANGTLPDVQACAYDHISWHLIGMSSSPEIFSVHFNGQTLEQNHYKVSTINLVGGASVTADMSVSRTGKWLISSLVAKHLQAGMYGYLNIKDCGNPDMKIKNWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKYKKAVFRQYEDGNFTKPTYAIWPKERGILGPVIKAKVRDTVTIVFKNLASRPYSIYVHGVSVSKDAEGAIYPSDPTHGKAVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPLLVCKHKALSGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSAVKKDDPKFYKSNVMYTLNGYASDRTEVLRFHQSEVVQWHLTSVGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLSSWGSCEMSNGMRLRFLDANYDDEDEGNEEEEEDDGDIFADIFIPSEGNKRRYYIAAEEVLWDYSPKTTFKKAIFRSYLDDTFQTPSTGGEYEKHLGILGPIIRAEVDDVIEIQFKNLASRPYSLHAHGLLYEKSSEGRSYDDKSPELFKKDDAIMPNGTYTYVWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDKYNRTIDIREFVLFFMVFDEEKSWYFPCSLHTFPAINGIPYQLQGLTMYKDENVHWHLLNMGGPKDIHVVNFHGQTFTEEGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQALFTVIDKDCKLPMGLASGIIQDSQISASGHVGYWEPKLARLNNTGKYNAWSIIKKEHEHPWIQIDLQRQVVITGIQTQGTVQLLQHSYTVEYFVTYSEDGQNWITFKGQMHFEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNRPTFRIELLGCEVEGCSVPLGMESGAIKNKEITASSYKKTWWSSWEPFLARLNLEGGTNAWQPEVNNKDQWLQIDLQHLTKITSIITQGATSMTTSMYVKTFSIHYTDDNSTWKPYLDVRTSMEKVFTGNINSDGHVKHFFKPPILSRFIRIIPKTWNQYIALRIELFGCEV 4bxw A 2.71 BS01 III F 1 N214 K241 I242 Y243 V244 H245 K246 W404 R407 N90 K117 I118 Y119 V120 H121 K122 W280 R283 Q6IT10 23869089 CRVDNGNCWHFCKHIQCSCAEGYLLGEDGHSCVAGGNFSCGRNIKIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPWIKRIMR 4bxw A 2.71 BS02 0GJ A 1 H211 Y262 D356 A357 C358 Q359 G360 S362 S381 S382 G383 G385 G393 H87 Y138 D232 A233 C234 Q235 G236 S238 S257 S258 G259 G261 G269 Q6IT10 23869089 CRVDNGNCWHFCKHIQCSCAEGYLLGEDGHSCVAGGNFSCGRNIKIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPWIKRIMR 4dhm A 1.70 BS02 0KB A 1 G53 R56 A57 R60 R129 Y130 L174 N175 V178 G57 R60 A61 R64 R126 Y127 L171 N172 V175 P31947 AMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 4dhp A 1.75 BS01 MG A 1 G78 E80 G75 E77 P31947 AMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 4dhp A 1.75 BS02 Y07 A 1 K49 G53 R56 R60 R129 Y130 L174 N175 V178 K53 G57 R60 R64 R126 Y127 L171 N172 V175 P31947 AMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT 4ew2 A 1.60 BS01 DXY A 1 R64 L85 M89 R90 I91 L92 V97 V139 A140 E141 V143 R64 L85 M89 R90 I91 L92 V97 V139 A140 E141 V143 6.3.4.13,6.3.3.1,2.1.2.2 P22102 23869564 ARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEEHH 4fdr B 2.10 BS01 III C 1 S105 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 G191 D192 N228 W231 N235 R238 D270 W273 S35 W72 N76 A78 S79 G80 T81 T85 Q111 W114 N118 G121 D122 N158 W161 N165 R168 D200 W203 P52293 QGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 4fdr B 2.10 BS02 III D 1 R315 N319 V321 G323 T328 E354 W357 S360 N361 A364 E396 W399 R245 N249 V251 G253 T258 E284 W287 S290 N291 A294 E326 W329 P52293 QGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 4fds B 1.88 BS01 III C 1 S105 F138 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 G191 D192 W231 N235 R238 D270 S34 F67 W71 N75 A77 S78 G79 T80 T84 Q110 W113 N117 G120 D121 W160 N164 R167 D199 P52293 GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS 4gb2 A 1.79 BS01 0LQ B 1 L23 D25 G27 A28 G48 G49 I50 V82 L23 D25 G27 A28 G48 G49 I50 V82 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03367 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 4gb2 B 1.79 BS01 0LQ B 1 L23 D25 G27 A28 D29 G48 G49 I50 P81 I84 L23 D25 G27 A28 D29 G48 G49 I50 P81 I84 3.4.23.16,2.7.7.49,2.7.7.7,3.1.26.13,3.1.13.2 P03367 PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF 4gd6 A 1.53 BS02 MA4 A 1 I221 V224 P226 I231 A248 V261 I263 A280 A284 I287 E288 I196 V199 P201 I206 A222 V234 I236 A253 A257 I260 E261 3.5.2.6 P0AD64 23145056 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4gd6 A 1.53 BS03 MA4 A 2 A217 L220 T235 N276 I279 A192 L195 T210 N249 I252 3.5.2.6 P0AD64 23145056 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4gd7 A 2.29 BS01 TIY A 1 F142 C180 W182 L192 P193 F105 C143 W145 L155 P156 2.1.1.45 P04818 PHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKME 4gd8 A 1.60 BS01 MXF A 1 S70 Y105 S130 V216 K234 T235 G236 A237 R244 S45 Y80 S105 V191 K209 T210 G211 A212 R218 3.5.2.6 P0AD64 23145056 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4gdb A 1.84 BS01 17O A 1 M69 S70 D104 S130 N132 T167 N170 G236 A237 M44 S45 D79 S105 N107 T142 N145 G211 A212 3.5.2.6 P0AD64 23145056 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4gdb A 1.84 BS03 MA4 A 2 A217 L220 T235 R244 N276 I279 A192 L195 T210 R218 N249 I252 3.5.2.6 P0AD64 23145056 SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 4gdg A 2.10 BS01 MG A 1 E69 D118 I120 E69 D118 I120 3.1.3.7 C4M4T9 MSFDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPVTVGDYSVQAYVNKKIHETFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDPIDGTLGFLRREQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKNGKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQCKYMAIASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHGIVASNGILHEETVNVVKDVLSDLK 4gdg A 2.10 BS02 AMP A 1 S198 S202 H203 D226 S227 K230 R244 Y251 E253 D257 S198 S202 H203 D226 S227 K230 R244 Y251 E253 D257 3.1.3.7 C4M4T9 MSFDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPVTVGDYSVQAYVNKKIHETFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDPIDGTLGFLRREQYAVCLAFMIDGDIKVGVLGCPNFEGGLIVAAQKGCGAKMFSVNDIKNGKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQCKYMAIASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNHGIVASNGILHEETVNVVKDVLSDLK 4gm3 A 3.39 BS01 III I 1 V48 S49 A65 G89 S91 D107 Y131 F133 F149 S175 K259 Y260 C261 F263 L321 V18 S19 A35 G59 S61 D77 Y101 F103 F119 S145 K229 Y230 C231 F233 L291 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm3 C 3.39 BS01 III K 1 A47 V48 A65 G89 I90 S91 D107 Y131 F133 F149 S175 K259 Y260 C261 F263 L321 A17 V18 A35 G59 I60 S61 D77 Y101 F103 F119 S145 K229 Y230 C231 F233 L291 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm3 D 3.39 BS01 III L 1 A47 S49 A65 G89 S91 D107 Y131 F133 S175 K259 Y260 C261 F263 L321 A17 S19 A35 G59 S61 D77 Y101 F103 S145 K229 Y230 C231 F233 L291 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm3 F 3.39 BS01 III N 1 V48 S49 G89 I90 S91 D107 Y131 F133 F149 S175 K259 Y260 C261 F263 L321 V18 S19 G59 I60 S61 D77 Y101 F103 F119 S145 K229 Y230 C231 F233 L291 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm3 G 3.39 BS01 III O 1 V48 S49 A65 G89 S91 D107 Y131 F133 Y260 C261 F263 L321 V18 S19 A35 G59 S61 D77 Y101 F103 Y230 C231 F233 L291 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm3 H 3.39 BS01 III P 1 A65 G89 I90 S91 D107 Y131 F133 F149 S175 K259 Y260 C261 F263 L321 A35 G59 I60 S61 D77 Y101 F103 F119 S145 K229 Y230 C231 F233 L291 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm8 A 2.60 BS01 III E 1 G89 I90 S91 D107 Y131 F133 F149 Y260 C261 F263 I305 L321 G59 I60 S61 D77 Y101 F103 F119 Y228 C229 F231 I273 L289 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm8 B 2.60 BS01 III F 1 S49 A65 G89 I90 S91 D107 Y131 F133 F149 Y260 C261 F263 I305 L321 S17 A33 G57 I58 S59 D75 Y99 F101 F117 Y226 C227 F229 I271 L287 P61964 23210835 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4gm8 C 2.60 BS01 III G 1 A47 S49 G89 I90 S91 D107 Y131 F133 F149 Y260 C261 F263 I305 L321 A17 S19 G59 I60 S61 D77 Y101 F103 F119 Y228 C229 F231 I273 L289 P61964 23210835 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC 4hfz A 2.69 BS01 III B 1 L54 L57 G58 I61 M62 Y67 Q72 H73 V75 V93 K94 H96 I99 Y100 L29 L32 G33 I36 M37 Y42 Q47 H48 V50 V68 K69 H71 I74 Y75 6.3.2.- Q00987 TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDAAQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLV 4hfz C 2.69 BS01 III D 1 L54 G58 I61 M62 Y67 Q72 H73 V93 K94 H96 Y100 L38 G42 I45 M46 Y51 Q56 H57 V77 K78 H80 Y84 6.3.2.- Q00987 SQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDAAQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLV 4hg3 A 1.93 BS01 AKG A 1 K127 F131 C169 Y170 R173 F195 T196 T199 K124 F128 C166 Y167 R170 F192 T193 T196 3.5.-.- P47016 KLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH 4hg3 B 1.93 BS01 AKG B 1 K127 F131 C169 Y170 R173 A194 F195 T196 T199 K123 F127 C165 Y166 R169 A190 F191 T192 T195 3.5.-.- P47016 LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH 4hg5 A 1.91 BS01 OAA A 1 K127 F131 C169 Y170 R173 F195 T199 K124 F128 C166 Y167 R170 F192 T196 3.5.-.- P47016 KLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH 4hg5 C 1.91 BS01 OAA C 1 F131 C169 Y170 R173 A194 F195 T199 F127 C164 Y165 R168 A189 F190 T194 3.5.-.- P47016 LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLF 4hg5 D 1.91 BS01 OAA D 1 F131 C169 Y170 R173 F195 T196 T199 F127 C165 Y166 R169 F191 T192 T195 3.5.-.- P47016 LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLF 4hg7 A 1.60 BS01 NUT A 1 L54 G58 I61 M62 Q72 H73 V75 V93 H96 I99 Y100 L37 G41 I44 M45 Q55 H56 V58 V76 H79 I82 Y83 6.3.2.- Q00987 QIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDAAQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLV 4hgd A 2.04 BS01 KGT A 1 E45 H93 K127 F131 E143 S169 Y170 R173 A194 F195 T196 T199 R250 E41 H89 K123 F127 E138 S164 Y165 R168 A189 F190 T191 T194 R243 3.5.-.- P47016 LKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNPILKESKSVQPGKAIPDIIESPLGKLGSAISYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLF 4hra A 3.15 BS01 EP6 A 1 D161 G163 S164 G165 V169 V185 E186 K187 G221 D222 F223 F239 N241 Y312 D150 G152 S153 G154 V158 V174 E175 K176 G210 D211 F212 F228 N230 Y298 2.1.1.43 Q8TEK3 23801631 KLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPTSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVGKPVSYYLHTIDRTILENYFSSLKNPKL 4i4i A 2.49 BS02 PEP B 1 R154 R211 K213 K214 H215 R154 R211 K213 K214 H215 2.7.1.11 P00512 23859543 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDAATSHERTYVIEVMGRHAGDIALWSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALANKHTIDQRMYALSKELSI 4i4i B 2.49 BS01 PEP A 1 R154 G185 R211 K213 K214 H215 R154 G185 R211 K213 K214 H215 2.7.1.11 P00512 23859543 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDAATSHERTYVIEVMGRHAGDIALWSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALANKHTIDQRMYALSKELSI 4i4i C 2.49 BS02 PEP D 1 R154 G185 R211 K213 K214 R154 G185 R211 K213 K214 2.7.1.11 P00512 23859543 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDAATSHERTYVIEVMGRHAGDIALWSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALANKHTIDQRMYALSKELSI 4i6s A 1.54 BS01 FUC A 1 R17 E28 C30 Y37 G39 A40 W81 R16 E27 C29 Y36 G38 A39 W80 D8NA05 SVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCADGNGWTKGAYTAT 4i6s B 1.54 BS03 FUC B 1 R17 E28 C30 Y37 G39 A40 I61 W81 R17 E28 C30 Y37 G39 A40 I61 W81 D8NA05 SSVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCADGNGWTKGAYTATN 4i6s C 1.54 BS03 FUC C 1 R62 E73 R61 E72 D8NA05 SVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCADGNGWTKGAYTAT 4i6s C 1.54 BS05 FUL C 2 R17 E28 Y37 G39 A40 I61 R16 E27 Y36 G38 A39 I60 D8NA05 SVQTAATSWGTVPSIRVYTANNGKITERCWDGKGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCADGNGWTKGAYTAT 4inq A 2.20 BS01 PIF A 1 L655 S656 S657 I658 A659 M660 L673 K717 N720 H745 R746 Q769 N780 K941 E945 Q948 R949 L31 S32 S33 I34 A35 M36 L49 K93 N96 H121 R122 Q145 N156 K317 E321 Q324 R325 P38713 23791945 KSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERRNKGQDVEPKYFEKVSKNEWKYITGPKSYWERRKKHDWSDISQLW 4iri A 2.77 BS01 NUC B 1 G292 Y345 R350 R353 Y354 Y356 K363 R368 Y369 G1 Y54 R59 R62 Y63 Y65 K72 R77 Y78 P11308 GQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPH 4iri A 2.77 BS02 NUC C 1 Q295 L296 W334 K338 K340 M343 K347 R350 Y354 Y355 K358 Q4 L5 W43 K47 K49 M52 K56 R59 Y63 Y64 K67 P11308 GQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPH 4iz6 A 2.40 BS01 1HZ A 1 N235 Y236 S240 G309 A310 R311 V331 F332 G333 M334 V339 Q355 D415 V427 K432 K441 N233 Y234 S238 G307 A308 R309 V329 F330 G331 M332 V337 Q353 D413 V425 K430 K439 2.7.7.58,2.3.1.- P0ADI4 SIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGGTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASAGPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK 4iz6 A 2.40 BS02 PNS A 1 S575 V576 M579 S569 V570 M573 2.7.7.58,2.3.1.- P0ADI4 SIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGGTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASAGPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK 4iz6 B 2.40 BS01 PNS A 1 I230 P231 H234 Y236 V279 G438 G439 E440 I227 P228 H231 Y233 V276 G435 G436 E437 2.7.7.58,2.3.1.- P0ADI4 SIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASAGRASIPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK 4iz6 B 2.40 BS02 1HZ B 1 N235 Y236 S240 G309 A310 R311 V331 F332 G333 V339 D415 V427 K441 N232 Y233 S237 G306 A307 R308 V328 F329 G330 V336 D412 V424 K438 2.7.7.58,2.3.1.- P0ADI4 SIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASAGRASIPASKAALREVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK 4j5y A 2.10 BS01 ATP A 1 Y25 K31 T61 V63 Y22 K28 T58 V60 Q9HUM0 GHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j5y C 2.10 BS01 ATP C 1 Y25 G29 K31 T61 Y22 G26 K28 T58 Q9HUM0 GHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j5y C 2.10 BS02 ATP D 1 L26 I30 L32 Q52 L23 I27 L29 Q49 Q9HUM0 GHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j6w A 1.80 BS02 C A 1 H5 Q8 Q41 F42 K56 H57 H1 Q4 Q37 F38 K52 H53 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j6w A 1.80 BS03 MG A 1 D9 F39 D40 K56 D5 F35 D36 K52 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j6w A 1.80 BS04 CTP B 1 F42 Y55 H57 F38 Y51 H53 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j6w B 1.80 BS02 C D 1 F42 H57 F38 H53 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRL 4j6w B 1.80 BS03 CTP D 1 L26 N28 I30 L22 N24 I26 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRL 4j6w C 1.80 BS02 C C 1 H5 Q8 Q41 F42 K56 H1 Q4 Q37 F38 K52 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRL 4j6w D 1.80 BS02 CTP D 1 Y25 G29 K31 S60 T61 Y21 G25 K27 S56 T57 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVR 4j6w D 1.80 BS03 MG D 1 F42 Y55 K56 H57 F38 Y51 K52 H53 Q9HUM0 HSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVR 4j6w E 1.80 BS03 C E 1 G4 Q8 Q41 F42 K56 H57 G1 Q5 Q38 F39 K53 H54 Q9HUM0 GHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVR 4j6w F 1.80 BS01 CTP C 1 L26 I30 L23 I27 Q9HUM0 GHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLPS 4j6x A 2.22 BS01 UTP A 1 N13 R16 K17 S38 F39 N8 R11 K12 S33 F34 Q9HUM0 SLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4j6x E 2.22 BS01 UTP E 1 D9 N13 R16 K17 S38 F39 D6 N10 R13 K14 S35 F36 Q9HUM0 GHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP 4jal A 2.00 BS01 SAH A 1 N14 L78 T79 T80 F99 G100 P101 E102 G105 I120 R121 I122 M124 S130 M131 N132 L133 N15 L79 T80 T81 F100 G101 P102 E103 G106 I121 R122 I123 M125 S131 M132 N133 L134 2.1.1.207 P0AGJ7 23804755 MALNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRLRRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPETRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVL 4jal B 2.00 BS01 SAH B 1 L78 T79 T80 F99 G100 P101 E102 G105 I120 R121 I122 M124 S130 M131 L133 L79 T80 T81 F100 G101 P102 E103 G106 I121 R122 I123 M125 S131 M132 L134 2.1.1.207 P0AGJ7 23804755 MALNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRLRRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPETRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAV 4jng A 2.12 BS01 NUC L 1 Q12 R13 N14 A15 A16 F18 N19 P20 L45 K48 N76 H77 V82 V86 R95 V123 P125 L126 R166 M172 F176 K178 K179 R182 Q183 R184 Q9 R10 N11 A12 A13 F15 N16 P17 L42 K45 N73 H74 V79 V83 R92 V120 P122 L123 R163 M169 F173 K175 K176 R179 Q180 R181 H2AM13 23798666 QFIFEDVPQRNAATFNPEVGYVAFIGKYGQQLNFGVARVFFLNQKKAKMVLHKTAQPSVDLTFGGVKFTVVNNHFPQYVSNPVPDNAITLHRMSGYLARWIADTCKASVLKLAEASAQIVMPLAEVKGCTWADGYTMYLGFAPGAEMFLDAFDFYPLVIEMHRVLKDNMDVNFMKKVLRQRYGTMTAEEWMTQKITEIKAAFNSVGQLAWAKSGFSPAARTFLQQF 4jng B 2.12 BS01 NUC L 1 N14 A15 A16 F18 P20 R41 K48 K51 N76 H77 V82 V86 T92 R95 V123 P125 L126 E128 R166 M172 F176 K178 K179 R182 Q183 R184 N1 A2 A3 F5 P7 R28 K35 K38 N63 H64 V69 V73 T79 R82 V110 P112 L113 E115 R153 M159 F163 K165 K166 R169 Q170 R171 H2AM13 23798666 NAATFNPEVGYVAFIGKYGQQLNFGVARVFFLNQKKAKMVLHKTAQPSVDLTFGGVKFTVVNNHFPQYVSNPVPDNAITLHRMSGYLARWIADTCKASVLKLAEASAQIVMPLAEVKGCTWADGYTMYLGFAPGAEMFLDAFDFYPLVIEMHRVLKDNMDVNFMKKVLRQRYGTMTAEEWMTQKITEIKAAFNSVGQLAWAKGFSPAARTFLQQ 4jng C 2.12 BS01 NUC L 1 R13 N14 A15 K48 K51 N76 H77 V82 V86 T92 R95 V123 P125 L126 E128 V129 R166 M172 F176 K179 R182 Q183 R9 N10 A11 K44 K47 N72 H73 V78 V82 T88 R91 V119 P121 L122 E124 V125 R162 M168 F172 K175 R178 Q179 H2AM13 23798666 FIFEDVPQRNAATFNPEVGYVAFIGKYGQQLNFGVARVFFLNQKKAKMVLHKTAQPSVDLTFGGVKFTVVNNHFPQYVSNPVPDNAITLHRMSGYLARWIADTCKASVLKLAEASAQIVMPLAEVKGCTWADGYTMYLGFAPGAEMFLDAFDFYPLVIEMHRVLKDNMDVNFMKKVLRQRYGTMTAEEWMTQKITEIKAAFNSVGQLAWAKGFSPAARTFLQQF 4jng D 2.12 BS01 NUC L 1 Q12 R13 N14 A15 A16 F18 N19 P20 L45 Q47 K48 K51 N76 H77 V82 T92 R95 V123 P125 L126 E128 R166 M172 F176 K179 R182 Q183 R184 Q11 R12 N13 A14 A15 F17 N18 P19 L44 Q46 K47 K50 N75 H76 V81 T91 R94 V122 P124 L125 E127 R165 M171 F175 K178 R181 Q182 R183 H2AM13 23798666 SSQFIFEDVPQRNAATFNPEVGYVAFIGKYGQQLNFGVARVFFLNQKKAKMVLHKTAQPSVDLTFGGVKFTVVNNHFPQYVSNPVPDNAITLHRMSGYLARWIADTCKASVLKLAEASAQIVMPLAEVKGCTWADGYTMYLGFAPGAEMFLDAFDFYPLVIEMHRVLKDNMDVNFMKKVLRQRYGTMTAEEWMTQKITEIKAAFNSVGQLAWAKSAARTFLQQ 4jo1 L 2.03 BS01 III P 1 Y28 N32 A34 Y49 L89 G91 Y92 C94 A96 Y29 N33 A35 Y50 L90 G92 Y93 C95 A101 23864637 QVLTQTPSSVSTAVGSAVTINCQSSQNVYSNNNLAWFQQKPGQPPRLLIYDASKLASGVPSRFKGSGSGTQFTFTISDVQCDDAATFYCLGGYDCSSGDCAAFGGGTEVVVRGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVTWEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVTQGTTSVVQSFNRGDC 4jo1 L 2.03 BS02 CA L 1 A97 F98 A102 F103 23864637 QVLTQTPSSVSTAVGSAVTINCQSSQNVYSNNNLAWFQQKPGQPPRLLIYDASKLASGVPSRFKGSGSGTQFTFTISDVQCDDAATFYCLGGYDCSSGDCAAFGGGTEVVVRGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVTWEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVTQGTTSVVQSFNRGDC 4jo1 L 2.03 BS03 CA L 2 P8 S9 P7 S8 23864637 QVLTQTPSSVSTAVGSAVTINCQSSQNVYSNNNLAWFQQKPGQPPRLLIYDASKLASGVPSRFKGSGSGTQFTFTISDVQCDDAATFYCLGGYDCSSGDCAAFGGGTEVVVRGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVTWEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVTQGTTSVVQSFNRGDC 4jo1 H 2.03 BS01 III P 1 D34 C50 E52 S56 N95 F96 D33 C50 E52 S58 N99 F100 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCCGDTPSSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAPSTC 4jo1 H 2.03 BS02 CA L 1 E46 W47 E46 W47 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCCGDTPSSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAPSTC 4jo1 H 2.03 BS03 CA H 1 A58 Y59 A60 Y61 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCCGDTPSSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAPSTC 4jo2 L 2.50 BS01 III P 1 Y28 N32 A34 Y49 L89 G91 Y92 D93 C94 C95D A96 Y29 N33 A35 Y50 L90 G92 Y93 D94 C95 C100 A101 23864637 QVLTQTPSSVSTAVGSAVTINCQSSQNVYSNNNLAWFQQKPGQPPRLLIYDASKLASGVPSRFKGSGSGTQFTFTISDVQCDDAATFYCLGGYDCSSGDCAAFGGGTEVVVRGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVTWEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVTQGTTSVVQSFNRGDC 4jo2 H 2.50 BS01 III P 1 D34 C50 E52 S56 N95 F96 D33 C50 E52 S58 N99 F100 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAP 4jo2 H 2.50 BS02 CA L 1 E46 W47 E46 W47 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAP 4jo2 H 2.50 BS03 CA H 1 A58 Y59 K64 A60 Y61 K66 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAP 4jo2 I 2.50 BS01 III Q 1 D34 C50 E52 S56 N95 D33 C50 E52 S58 N99 23864637 QSLEESGGDLVQPGASLTLTCKASGFSFGNNYDMCWVRQAPGKGLEWIGCIETGSSDSAAYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARNFDLWGPGTLVIVSSGQPKAPSVFPLAPCSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAP 4jo3 L 2.60 BS01 III P 1 D1 I2 E27 Y92 S93 I94 S95 D1 I2 E27 Y92 S93 I94 S95 23864637 DIVMTQTPASVSAAVGGTVTINCQASETISNYLAWYQQKPGQPPKLLIYKASTLASGVSSRFKGSGSGTEYTLTISGVQCDDAATYYCQQGYSISDIDNSFGGGTEVVVKGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVTWEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVTQGTTSVVQSFNRGDC 4jo3 H 2.60 BS01 III P 1 N31 Y34 Y52 G53 R54 I56 F58 F97 A99 V100 T100F Y100G S100H T100I Y100K N30 Y33 Y52 G55 R56 I58 F60 F101 A103 V104 T110 Y111 S112 T113 Y115 23864637 QSLEESGGDLVKPGASLTLTCTASGFSFTNNYYMCWVRQAPGKGLEWIACIYGGGRDIVFYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARENFDAVGVGGGTYSTDYYFDLWGPGTLVIVSSGQPKAPSVFPLAPCCGDTPSATVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAP 4jo3 M 2.60 BS01 III Q 1 D1 I2 Y92 S93 I94 S95 D95A I95B D1 I2 Y92 S93 I94 S95 D96 I97 23864637 DIVMTQTPASVSAAVGGTVTINCQASETISNYLAWYQQKPGQPPKLLIYKASTLASGVSSRFKGSGSGTEYTLTISGVQCDDAATYYCQQGYSISDIDNSFGGGTEVVVKGDPVAPTVLIFPPAADQVATGTVTIVCVANKYFPDVTVTWEVDGTTQTTGIENSKTPQNSADCTYNLSSTLTLTSTQYNSHKEYTCKVTQGTTSVVQSFNRGDC 4jo3 I 2.60 BS01 III Q 1 N31 Y34 Y52 R54 I56 F58 V100B T100F Y100G S100H T100I Y100K N30 Y33 Y52 R56 I58 F60 V106 T110 Y111 S112 T113 Y115 23864637 QSLEESGGDLVKPGASLTLTCTASGFSFTNNYYMCWVRQAPGKGLEWIACIYGGGRDIVFYATWAKGRFTISKTSSTTVTLQMTSLTAADTATYFCARENFDAVGVGGGTYSTDYYFDLWGPGTLVIVSSGQPKAPSVFPLAPCCGDTPSATVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAP 4jpl A 1.41 BS01 HEM A 1 P44 R48 W51 P145 D146 A147 F158 L171 M172 A174 H175 L177 G178 K179 T180 H181 N184 S185 L230 T232 P41 R45 W48 P142 D143 A144 F155 L168 M169 A171 H172 L174 G175 K176 T177 H178 N181 S182 L227 T229 1.11.1.5 B3LRE1 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGGGANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 4jpl A 1.41 BS02 4JP A 1 H175 L177 G178 K179 T180 M228 L230 D233 H172 L174 G175 K176 T177 M225 L227 D230 1.11.1.5 B3LRE1 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGGGANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 4jqk A 1.36 BS02 1LN A 1 H175 L177 G178 M228 M229 D233 H172 L174 G175 M225 M226 D230 1.11.1.5 B3LRE1 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGGGANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 4jqk A 1.36 BS03 1LN A 2 K149 D150 W221 P231 Q238 K146 D147 W218 P228 Q235 1.11.1.5 B3LRE1 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGGGANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 4jqn A 1.36 BS02 HBA A 1 H175 L177 G178 K179 G190 G191 M228 L230 D233 H172 L174 G175 K176 G187 G188 M225 L227 D230 1.11.1.5 B3LRE1 LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGGGANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL 4js1 A 2.09 BS01 CTN A 1 S188 S189 A190 F211 S322 S323 G324 F343 C353 C364 T365 K376 S100 S101 A102 F123 S234 S235 G236 F255 C265 C276 T277 K288 2.4.99.1 P15907 PEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC 4js1 A 2.09 BS02 PO4 A 1 N212 N233 S322 S323 H370 N124 N145 S234 S235 H282 2.4.99.1 P15907 PEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC 4js2 A 2.30 BS01 C A 1 S189 A190 F211 N212 S322 S323 G324 F343 C353 Y354 C364 T365 L372 K376 S101 A102 F123 N124 S234 S235 G236 F255 C265 Y266 C276 T277 L284 K288 2.4.99.1 P15907 PEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC 4k19 A 2.74 BS01 1OD A 1 Y52 S68 L70 W79 R81 L94 Y100 L103 Y106 K125 Y132 K134 Y48 S64 L66 W75 R77 L90 Y96 L99 Y102 K121 Y128 K130 P80188 23755875 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 4k19 B 2.74 BS01 1OD B 1 A40 W79 L94 Y100 L103 Y106 F123 K125 F133 K134 A35 W71 L86 Y92 L95 Y98 F113 K115 F123 K124 P80188 23755875 SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLANAILREDKPQKMYATIYELDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNQHAMVFFKKVSQNREYFKITLYGRTKELTKENFIRFSKSLGLPENHIVFPVPIDQCI 4k19 C 2.74 BS01 FE C 1 W79 Y106 W78 Y105 P80188 23755875 DSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4k19 C 2.74 BS02 1OD C 1 Y52 S68 W79 R81 L94 Y100 L103 Y106 F123 K125 K134 Y51 S67 W78 R80 L93 Y99 L102 Y105 F122 K124 K133 P80188 23755875 DSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 4k1g A 1.90 BS01 NUC E 1 H7 F32 A69 Y72 H109 H182 D229 R230 H231 E261 H7 F32 A69 Y72 H109 H182 D229 R230 H231 E261 3.1.21.2 P0A6C1 MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPADSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKA 4k1g A 1.90 BS02 NUC F 1 R37 Q38 W39 Y72 L73 Q150 G151 S152 R37 Q38 W39 Y72 L73 Q150 G151 S152 3.1.21.2 P0A6C1 MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPADSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKA 4k1g A 1.90 BS03 NUC H 1 S9 A11 G12 N35 Q36 R37 S9 A11 G12 N35 Q36 R37 3.1.21.2 P0A6C1 MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPADSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKA 4k1g A 1.90 BS06 ZN A 3 D251 D254 D251 D254 3.1.21.2 P0A6C1 MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPADSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKA 4k1g B 1.90 BS02 NUC N 1 R37 Q38 W39 Y72 L73 L114 Q150 G151 S152 V228 R37 Q38 W39 Y72 L73 L114 Q150 G151 S152 V228 3.1.21.2 P0A6C1 MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPADSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQ 4kbf A 1.90 BS01 AMP A 1 F3 L21 T23 Q28 G48 T49 G50 K51 T52 L53 F3 L21 T23 Q28 G48 T49 G50 K51 T52 L53 Q72GF3 23765433 MEFKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAERLAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVVAVYGGTGYGKQKEALLRGADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLLFSATLPSWAKRLAERYMKNPVLINVIKDEPVTYEEEAVPAPVRGRLEVLSDLLYVASPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRVLVATDVAARGLDIPQVDLVVHYRLPDRAEAYQHRSGRTGRAGRGGRVVLLYGPRERRDVEALERAVGRRFKRVN 4kv8 A 2.30 BS01 1WT A 1 P95 L100 K101 K103 K104 S105 V106 Y181 Y188 V189 G190 P225 F227 W229 L234 H235 P236 Y318 P95 L100 K101 K103 K104 S105 V106 Y181 Y188 V189 G190 P225 F227 W229 L234 H235 P236 Y318 3.1.13.2 P04585 23809849 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSA 4kvm E 2.60 BS01 III I 1 E24 Y26 T74 H111 Y138 Y139 E24 Y26 T74 H111 Y138 Y139 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvm E 2.60 BS02 1XE I 1 N21 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 A118 A119 L122 Y123 T126 N21 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 A118 A119 L122 Y123 T126 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvm F 2.60 BS02 1XE J 1 N21 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 R117 A118 A119 L122 Y123 N21 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 R117 A118 A119 L122 Y123 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvm G 2.60 BS02 1XE K 1 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 A119 L122 Y123 T126 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 A119 L122 Y123 T126 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvm H 2.60 BS02 1XE L 1 N21 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 A118 A119 H121 L122 Y123 N21 L22 S75 V76 S77 V78 R83 H84 G86 L87 A88 K89 H111 V112 N116 A118 A119 H121 L122 Y123 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvo F 3.15 BS01 ACO F 1 N21 L22 V76 V78 R83 H84 L85 G86 L87 A88 H111 V112 N116 Y123 T126 N21 L22 V76 V78 R83 H84 L85 G86 L87 A88 H111 V112 N116 Y123 T126 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvo G 3.15 BS01 ACO G 1 N21 L22 V76 S77 V78 R83 H84 L85 G86 L87 A88 K89 H111 V112 N116 A118 H121 L122 Y123 T126 N21 L22 V76 S77 V78 R83 H84 L85 G86 L87 A88 K89 H111 V112 N116 A118 H121 L122 Y123 T126 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvo H 3.15 BS01 ACO H 1 N21 L22 E24 V76 S77 V78 R83 H84 L85 G86 L87 A88 K89 H111 V112 N116 R117 A118 L122 Y123 N21 L22 E24 V76 S77 V78 R83 H84 L85 G86 L87 A88 K89 H111 V112 N116 R117 A118 L122 Y123 2.3.1.88 Q9UTI3 MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kvx A 2.00 BS01 ACO A 1 N21 E24 S75 V76 S77 V78 R83 H84 L85 G86 L87 A88 K89 H111 V112 N116 R117 A118 A119 H121 L122 Y123 T126 N20 E23 S74 V75 S76 V77 R82 H83 L84 G85 L86 A87 K88 H110 V111 N115 R116 A117 A118 H120 L121 Y122 T125 2.3.1.88 Q9UTI3 DIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFS 4kw6 B 3.00 BS01 QDO B 1 F47 C49 F48 C50 1.11.1.15 J7HJM3 HMSKAFIGKPAPDFATKAVFDGDFVDVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSDRFPEFKNLNVAVLACSTDSVFSHLAWINTPRKHGGLGDMKIPVLADTNHQIAKDYGVLKDDEGIAYRGLFIIDPKGILRQITINDLPVGRSVDETLRLVQAFQYTDKHGEVC 4kwe A 2.91 BS01 GDP A 1 G17 G18 G19 N22 G101 E102 G104 G105 T106 G107 E136 R140 F180 A183 D184 G10 G11 G12 N15 G94 E95 G97 G98 T99 G100 E129 R133 F173 A176 D177 P64170 LAVIKVVGIGGGGVNAVNRMIEQGLKGVEFIAINTDAQALLMSDADVKLDVGRDSTRGLGAGADPEVGRKAAEDAKDEIEELLRGADMVFVTAGEGGGTGTGGAPVVASIARKLGALTVGVVTRPFSFEGKRRSNQAENGIAALRESCDTLIVIPNDRLLQMGDAAVSLMDAFRSADEVLLNGVQGITDLITTPGLINVDFADVKGIMSGAGTALMGIGSARGEGRSLKAAEIAINSPLLEASMEGAQGVLMSIAGGSDLGLFEINEAASLVQDAAHPDANIIFGTVIDDSLGDEVRVTVIAAGF 4kwh A 1.70 BS01 NAP A 1 G13 S15 R16 G17 I18 H36 A38 T39 G40 A63 E64 L65 N97 A98 G99 V100 M101 R116 V120 V145 S146 Y160 K164 P190 G191 S192 T193 N195 G12 S14 R15 G16 I17 H35 A37 T38 G39 A62 E63 L64 N96 A97 G98 V99 M100 R115 V119 V144 S145 Y159 K163 P189 G190 S191 T192 N194 Q9ZGC1 23848284 GNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4kwi A 2.00 BS01 NAP A 1 G13 S15 R16 G17 I18 H36 A38 T39 G40 A63 L65 N97 A98 G99 V100 R116 V120 V145 S146 S147 Y160 K164 P190 G191 S192 T193 N195 G12 S14 R15 G16 I17 H35 A37 T38 G39 A62 L64 N96 A97 G98 V99 R115 V119 V144 S145 S146 Y159 K163 P189 G190 S191 T192 N194 Q9ZGC1 23848284 GNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4kwi A 2.00 BS02 1TJ A 1 M101 G148 L149 V152 Q157 P190 G191 S192 L199 L209 L212 T250 M100 G147 L148 V151 Q156 P189 G190 S191 L198 L208 L211 T249 Q9ZGC1 23848284 GNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4kwi B 2.00 BS01 NAP B 1 G13 S15 R16 G17 I18 H36 A38 T39 G40 A63 L65 N97 A98 V100 R116 V145 S146 Y160 K164 P190 G191 S192 T193 N195 G16 S18 R19 G20 I21 H39 A41 T42 G43 A66 L68 N100 A101 V103 R119 V148 S149 Y163 K167 P193 G194 S195 T196 N198 Q9ZGC1 23848284 HHRSGNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4kwi B 2.00 BS02 1TJ B 1 M101 M103 G148 L149 V152 Q157 P190 G191 L209 L212 T250 M104 M106 G151 L152 V155 Q160 P193 G194 L212 L215 T253 Q9ZGC1 23848284 HHRSGNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4kx7 A 2.15 BS01 ZN A 1 H393 H397 E416 H318 H322 E341 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kx8 A 2.40 BS01 III C 1 E223 T356 G357 A358 M359 E360 N371 R386 V390 H393 E394 H397 E416 Y479 R887 E148 T281 G282 A283 M284 E285 N296 R311 V315 H318 E319 H322 E341 Y404 R808 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kx9 A 2.25 BS02 ARG A 1 E223 T356 A358 E360 E394 E416 Y479 R887 E148 T281 A283 E285 E319 E341 Y404 R808 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kxa A 2.40 BS01 CA A 1 D221 E223 D146 E148 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kxa A 2.40 BS03 ASP A 1 E223 T356 A358 E360 Y479 R887 E148 T281 A283 E285 Y404 R808 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kxb A 2.40 BS02 BES A 1 E223 T356 G357 A358 M359 E360 V390 H393 E394 H397 E416 F474 Y479 R887 E148 T281 G282 A283 M284 E285 V315 H318 E319 H322 E341 F399 Y404 R808 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kxc A 2.40 BS02 GLU A 1 E223 T356 A358 M359 E360 E394 E416 Y479 R887 E148 T281 A283 M284 E285 E319 E341 Y404 R808 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kxd A 2.15 BS01 CA A 1 D221 H222 E223 D146 H147 E148 3.4.11.7 Q07075 DICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLL 4kxt A 2.29 BS01 NUC B 1 S218 A219 H269 Y277 F292 L294 Q295 Y309 F310 K313 Y314 H334 T335 Y336 L337 R349 T359 I363 T366 R373 L520 G522 K523 T524 Y527 K531 Q543 C544 Q546 N549 T557 N560 L561 K564 K568 K707 R712 H751 I754 Q755 T757 S758 R759 Y788 R790 C791 R793 S796 Y802 Y813 S183 A184 H234 Y242 F257 L259 Q260 Y274 F275 K278 Y279 H299 T300 Y301 L302 R314 T324 I328 T331 R338 L485 G487 K488 T489 Y492 K496 Q508 C509 Q511 N514 T522 N525 L526 K529 K533 K672 R677 H716 I719 Q720 T722 S723 R724 Y753 R755 C756 R758 S761 Y767 Y778 Q9UL18 23809764 QAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKRDPQALAKAVQVHQDTLRTMYFA 4l04 A 2.87 BS03 NAP A 1 K72 A74 T75 T77 R82 N96 L288 G289 H309 G310 T311 V312 T313 R314 H315 T327 N328 D375 K68 A70 T71 T73 R78 N92 L284 G285 H305 G306 T307 V308 T309 R310 H311 T323 N324 D371 1.1.1.42 O75874 23731180 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS 4l04 B 2.87 BS02 CA A 2 D275 D279 A308 D273 D277 A306 1.1.1.42 O75874 23731180 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 4l04 B 2.87 BS05 NAP B 1 K72 A74 T75 I76 T77 N96 L288 G289 H309 G310 T311 V312 T313 R314 H315 N328 K70 A72 T73 I74 T75 N94 L286 G287 H307 G308 T309 V310 T311 R312 H313 N326 1.1.1.42 O75874 23731180 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 4l04 D 2.87 BS03 CA D 1 R109 D275 S278 D279 R107 D273 S276 D277 1.1.1.42 O75874 23731180 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 4l04 E 2.87 BS01 AKG E 1 T77 S94 R100 R109 R132 D275 A308 T74 S91 R97 R106 R129 D272 A305 1.1.1.42 O75874 23731180 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS 4l04 E 2.87 BS03 NAP E 1 K72 A74 T75 I76 T77 R82 N96 L288 H309 G310 T311 V312 T313 R314 H315 T327 N328 K69 A71 T72 I73 T74 R79 N93 L285 H306 G307 T308 V309 T310 R311 H312 T324 N325 1.1.1.42 O75874 23731180 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKLS 4l04 F 2.87 BS04 NAP F 1 A74 T75 I76 T77 R82 N96 L288 G289 A307 H309 G310 T311 V312 T313 R314 H315 N328 D375 A72 T73 I74 T75 R80 N94 L286 G287 A305 H307 G308 T309 V310 T311 R312 H313 N326 D373 1.1.1.42 O75874 23731180 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNNTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 4l49 A 2.13 BS01 HEM A 1 T101 Q108 R112 L244 L245 G248 T252 V253 L294 V295 D297 R299 Q322 T349 F350 G351 H355 C357 G359 A363 T92 Q99 R103 L235 L236 G239 T243 V244 L285 V286 D288 R290 Q313 T340 F341 G342 H346 C348 G350 A354 1.14.15.1 P00183 23865948 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCAGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 4l4a A 2.10 BS01 HEM A 1 P100 T101 Q108 R112 V119 L244 L245 G248 T252 V253 L294 V295 D297 R299 Q322 T349 F350 G351 H355 C357 A358 G359 A363 P91 T92 Q99 R103 V110 L235 L236 G239 T243 V244 L285 V286 D288 R290 Q313 T340 F341 G342 H346 C348 A349 G350 A354 1.14.15.1 P00183 23865948 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLGYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCAGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 4l4c A 2.20 BS01 HEM A 1 T101 Q108 R112 V119 L244 L245 G248 G249 T252 V253 L294 V295 D297 R299 Q322 T349 F350 G351 H355 C357 P358 A363 T92 Q99 R103 V110 L235 L236 G239 G240 T243 V244 L285 V286 D288 R290 Q313 T340 F341 G342 H346 C348 P349 A354 1.14.15.1 P00183 23865948 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLGYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCPGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 4l4c B 2.20 BS01 HEM B 1 P100 T101 Q108 R112 V119 F163 L244 G248 G249 T252 L294 V295 D297 R299 Q322 T349 F350 G351 H355 C357 P358 G359 A363 P91 T92 Q99 R103 V110 F154 L235 G239 G240 T243 L285 V286 D288 R290 Q313 T340 F341 G342 H346 C348 P349 G350 A354 1.14.15.1 P00183 23865948 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLGYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCPGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 4l4e A 1.26 BS01 HEM A 1 T101 R112 V119 L244 L245 G248 T252 V253 L294 V295 D297 R299 Q322 T349 F350 G351 H355 C357 G359 A363 T92 R103 V110 L235 L236 G239 T243 V244 L285 V286 D288 R290 Q313 T340 F341 G342 H346 C348 G350 A354 1.14.15.1 P00183 23865948 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLGYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCAGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 4l4g A 1.55 BS01 HEM A 1 P100 T101 Q108 R112 V119 F163 L244 L245 T252 V253 L294 V295 D297 R299 Q322 T349 F350 G351 H355 C357 P358 G359 A363 P91 T92 Q99 R103 V110 F154 L235 L236 T243 V244 L285 V286 D288 R290 Q313 T340 F341 G342 H346 C348 P349 G350 A354 1.14.15.1 P00183 23865948 NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCNGGHWIATRGQLIREAYEDYRHFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIPHLGYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELIERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGHGSHLCPGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAV 4l5r C 1.87 BS01 NUC A 1 K76 S166 G167 H222 R224 K225 G226 N227 G235 N236 K31 S121 G122 H177 R179 K180 G181 N182 G190 N191 Q9R002 23850291 TPKKNISKGAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESKYYRVKVFNMDLKEKFTENQFITISKYFNSSGILEINETATVSEAAPNQMFEVPKNIIRSAKETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIKVVWDKEQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGE 4l5r C 1.87 BS02 NUC B 1 K48 K53 G54 K180 N182 D183 K184 S185 T187 K198 K3 K8 G9 K135 N137 D138 K139 S140 T142 K153 Q9R002 23850291 TPKKNISKGAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESKYYRVKVFNMDLKEKFTENQFITISKYFNSSGILEINETATVSEAAPNQMFEVPKNIIRSAKETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIKVVWDKEQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGE 4l6j D 3.40 BS01 NUC A 1 K7 P8 Y9 T10 P11 R13 R14 F15 F21 E28 L37 K38 K39 T40 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 R54 G56 H58 K59 R60 L61 Y62 R63 Y84 P86 R88 D99 G100 E101 K102 L147 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 L177 P178 S179 E181 R183 A199 H201 K202 L206 G207 K208 A209 G210 R211 S212 R213 W214 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 H233 G235 E237 G238 R239 A240 P241 R242 G243 R244 P245 P246 A247 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 K261 R262 R263 K264 S266 R268 F269 K6 P7 Y8 T9 P10 R12 R13 F14 F20 E27 L36 K37 K38 T39 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 R53 G55 H57 K58 R59 L60 Y61 R62 Y83 P85 R87 D98 G99 E100 K101 L146 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 L176 P177 S178 E180 R182 A198 H200 K201 L205 G206 K207 A208 G209 R210 S211 R212 W213 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 H232 G234 E236 G237 R238 A239 P240 R241 G242 R243 P244 P245 A246 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 K260 R261 R262 K263 S265 R267 F268 Q72I07 23824292 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIA 4l6j D 3.40 BS02 MG D 1 G42 R43 T50 V51 G41 R42 T49 V50 Q72I07 23824292 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIA 4l6j D 3.40 BS03 MG D 2 R88 I106 R157 R87 I105 R156 Q72I07 23824292 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIA 4l6j E 3.40 BS01 NUC A 1 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 K57 R58 N60 R61 P62 L63 G65 H66 K69 R76 L78 R79 E80 R82 R101 S108 K109 G110 R111 G112 F113 G115 K118 R119 F122 A123 P126 D127 S128 H129 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 G153 K154 M156 A157 H159 Y160 E163 R164 V165 T166 M168 L170 K185 A187 V188 P189 G190 P191 N192 K203 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 K57 R58 N60 R61 P62 L63 G65 H66 K69 R76 L78 R79 E80 R82 R101 S108 K109 G110 R111 G112 F113 G115 K118 R119 F122 A123 P126 D127 S128 H129 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 G153 K154 M156 A157 H159 Y160 E163 R164 V165 T166 M168 L170 K185 A187 V188 P189 G190 P191 N192 K203 Q72I04 23824292 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKA 4l6j E 3.40 BS03 MG E 2 K118 N121 Y160 K118 N121 Y160 Q72I04 23824292 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKA 4l6j F 3.40 BS01 NUC A 1 N29 H31 L32 W34 E35 R38 W39 Q40 L41 K43 R44 R45 R46 G47 T48 A49 S50 T51 K52 T53 R54 V57 A58 Y59 S60 G61 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 I78 P81 I82 F83 V84 G85 V88 V89 F90 G91 P92 P94 R95 Y99 T100 L101 P102 K103 K104 V105 R106 K107 K108 K135 T136 R165 R168 N169 L170 P171 L176 A177 E179 G180 N182 Y184 R205 N24 H26 L27 W29 E30 R33 W34 Q35 L36 K38 R39 R40 R41 G42 T43 A44 S45 T46 K47 T48 R49 V52 A53 Y54 S55 G56 R57 K58 Q62 K63 H64 G66 R67 A68 R69 H70 G71 I73 P76 I77 F78 V79 G80 V83 V84 F85 G86 P87 P89 R90 Y94 T95 L96 P97 K98 K99 V100 R101 K102 K103 K130 T131 R160 R163 N164 L165 P166 L171 A172 E174 G175 N177 Y179 R200 Q72I05 23824292 MYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4l6j F 3.40 BS02 MG F 1 H75 G76 A80 I82 F83 H70 G71 A75 I77 F78 Q72I05 23824292 MYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4l6j F 3.40 BS03 MG F 2 L170 V173 L165 V168 Q72I05 23824292 MYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4l6j F 3.40 BS04 MG F 3 K135 T136 K137 K130 T131 K132 Q72I05 23824292 MYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4l6j F 3.40 BS05 MG F 4 R62 I64 I78 R57 I59 I73 Q72I05 23824292 MYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4l6j G 3.40 BS01 NUC A 1 K36 V38 N40 G42 G44 E45 T71 R72 A73 K74 I77 F80 L82 G89 R91 N121 S124 D126 R128 N130 N132 L133 G134 L135 R136 G154 M155 D156 A158 K35 V37 N39 G41 G43 E44 T70 R71 A72 K73 I76 F79 L81 G88 R90 N120 S123 D125 R127 N129 N131 L132 G133 L134 R135 G153 M154 D155 A157 Q72I16 23824292 PLDLALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4l6j G 3.40 BS02 NUC B 1 L3 N27 W29 E30 Q66 K67 A69 V70 T71 R91 V92 T93 R95 R96 R98 L2 N26 W28 E29 Q65 K66 A68 V69 T70 R90 V91 T92 R94 R95 R97 Q72I16 23824292 PLDLALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4l6j G 3.40 BS03 MG G 1 G44 K47 F80 K81 G43 K46 F79 K80 Q72I16 23824292 PLDLALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4l6j H 3.40 BS01 NUC A 1 R59 R60 K62 S63 G66 L67 T70 L71 N74 G108 F109 S110 K138 Q139 G142 Q143 A146 R152 K153 Y157 H158 K160 R48 R49 K51 S52 G55 L56 T59 L60 N63 G97 F98 S99 K127 Q128 G131 Q132 A135 R141 K142 Y146 H147 K149 Q72I19 23824292 PKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVR 4l6j I 3.40 BS01 NUC A 1 N11 K22 P23 G24 Y25 R27 N28 Y29 R33 S42 K45 R50 N11 K22 P23 G24 Y25 R27 N28 Y29 R33 S42 K45 R50 Q72GV5 23824292 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGITIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVV 4l6j J 3.40 BS01 NUC A 1 K25 T26 V28 T45 L46 G47 R48 T51 R58 K60 P67 N68 T86 G87 K88 K89 Q92 R97 Y98 S99 Y101 P102 G103 G104 L105 K106 K112 H124 A125 G128 M129 P131 K132 G133 P134 L135 R137 K141 P152 Q154 K1 T2 V4 T21 L22 G23 R24 T27 R34 K36 P43 N44 T62 G63 K64 K65 Q68 R73 Y74 S75 Y77 P78 G79 G80 L81 K82 K88 H100 A101 G104 M105 P107 K108 G109 P110 L111 R113 K117 P128 Q130 Q72IN1 23824292 KTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 4l6j K 3.40 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 K26 G27 S28 N29 A30 K31 Y32 V40 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 M1 Q3 Q5 T6 Y7 I22 R23 K26 G27 S28 N29 A30 K31 Y32 V40 S42 K44 G55 V57 K66 K67 E68 K70 R78 N82 Q72I14 23824292 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEVKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4l6j K 3.40 BS03 MG K 2 R104 V121 R104 V121 Q72I14 23824292 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEVKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4l6j K 3.40 BS04 MG K 3 A46 E54 A46 E54 Q72I14 23824292 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEVKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4l6j L 3.40 BS01 NUC A 1 P8 N9 G11 N13 R15 R16 K17 R18 V19 G20 R21 G24 S25 G26 H27 K29 A31 T32 R33 G34 H35 K36 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 R90 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 P4 N5 G7 N9 R11 R12 K13 R14 V15 G16 R17 G20 S21 G22 H23 K25 A27 T28 R29 G30 H31 K32 Q34 K35 S36 R37 S38 G39 L41 K42 D43 P44 R45 R46 F47 G49 G50 R51 S52 L55 M56 R57 L58 P59 K60 R61 G62 M63 Q64 G65 Q66 V67 P68 G69 E70 I71 K72 R73 Q77 N80 R86 G100 K103 K104 K109 L111 G112 E113 S127 K128 S129 Q72I23 23824292 DLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4l6j L 3.40 BS02 MG L 1 P48 R50 E52 P44 R46 E48 Q72I23 23824292 DLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4l6j L 3.40 BS03 MG L 2 H35 K36 Q38 R41 H31 K32 Q34 R37 Q72I23 23824292 DLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4l6j M 3.40 BS01 NUC A 1 R6 M7 K8 Y9 R10 K11 Q12 Q13 R14 G15 R16 K18 T21 K22 D25 Y26 F29 A40 W41 Q45 Q46 A49 R56 R59 K63 I66 R67 F69 D71 Y74 K76 K77 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 L125 P126 K128 R1 M2 K3 Y4 R5 K6 Q7 Q8 R9 G10 R11 K13 T16 K17 D20 Y21 F24 A35 W36 Q40 Q41 A44 R51 R54 K58 I61 R62 F64 D66 Y69 K71 K72 E75 V76 R77 M78 G79 K80 G81 R96 R114 I115 H118 K119 L120 P121 K123 Q72I11 23824292 RMKYRKQQRGRLKGATKGGDYVAFGDFGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDE 4l6j N 3.40 BS01 NUC A 1 R2 H3 L4 K5 S6 G7 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L65 R68 Q71 R77 R90 G92 G93 Y94 T95 R96 K99 R104 R105 G106 D107 A109 R1 H2 L3 K4 S5 G6 R7 K8 L9 N10 R11 H12 S13 S14 H15 R16 A18 L19 R21 N22 Q23 K25 S26 I33 T34 T35 T36 P38 K39 K41 R44 G45 D48 H49 H52 R56 L59 H60 R62 R63 L64 R67 Q70 R76 R89 G91 G92 Y93 T94 R95 K98 R103 R104 G105 D106 A108 Q72I33 23824292 RHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4l6j N 3.40 BS02 MG N 1 R96 V97 R95 V96 Q72I33 23824292 RHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4l6j N 3.40 BS03 MG N 2 T36 T37 K40 T35 T36 K39 Q72I33 23824292 RHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4l6j O 3.40 BS02 NUC B 1 R15 K19 R25 F29 R30 S31 L32 H34 Y36 Q38 I40 V46 T47 S50 S52 A55 L56 G60 N61 K62 T63 Y92 K93 H95 R97 R5 K9 R15 F19 R20 S21 L22 H24 Y26 Q28 I30 V36 T37 S40 S42 A45 L46 G50 N51 K52 T53 Y82 K83 H85 R87 Q72I20 23824292 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG 4l6j O 3.40 BS03 MG B 1 F29 Y92 F19 Y82 Q72I20 23824292 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG 4l6j O 3.40 BS04 MG O 1 V85 R106 V75 R96 Q72I20 23824292 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG 4l6j P 3.40 BS01 NUC A 1 N2 R3 G4 A5 R23 R51 R53 R54 N55 G56 N58 T60 R95 R96 A97 K98 Y100 F101 K113 R115 K119 K123 N2 R3 G4 A5 R23 R51 R53 R54 N55 G56 N58 T60 R95 R96 A97 K98 Y100 F101 K113 R115 K119 K123 Q72JU9 23824292 MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDKDRAAERAAKEEVQK 4l6j Q 3.40 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 V9 R10 R11 R12 K13 H14 K15 K16 K19 G23 Y24 W25 G26 L27 R28 K30 S31 F32 R33 K34 R36 E37 A41 A42 Y45 A46 Y47 A48 H49 R50 K51 R52 R53 K54 R55 F57 R58 R59 W61 I62 N66 R70 N75 Y76 S77 H81 K84 R92 K93 N94 P1 R2 A3 K4 T5 G6 V7 V8 R9 R10 R11 K12 H13 K14 K15 K18 G22 Y23 W24 G25 L26 R27 K29 S30 F31 R32 K33 R35 E36 A40 A41 Y44 A45 Y46 A47 H48 R49 K50 R51 R52 K53 R54 F56 R57 R58 W60 I61 N65 R69 N74 Y75 S76 H80 K83 R91 K92 N93 Q72L76 23824292 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQG 4l6j R 3.40 BS01 NUC A 1 G8 G9 K10 E23 K24 R66 K68 K69 V72 K74 F75 K76 A77 K78 Q80 Y81 R82 R83 K84 K85 G86 H87 R88 Q89 P90 G8 G9 K10 E23 K24 R66 K68 K69 V72 K74 F75 K76 A77 K78 Q80 Y81 R82 R83 K84 K85 G86 H87 R88 Q89 P90 Q72HR2 23824292 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4l6j R 3.40 BS02 MG R 1 K76 A77 K76 A77 Q72HR2 23824292 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4l6j R 3.40 BS03 MG R 2 K78 V79 K78 V79 Q72HR2 23824292 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4l6j R 3.40 BS04 MG R 3 A77 K78 V79 Q80 A77 K78 V79 Q80 Q72HR2 23824292 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4l6j S 3.40 BS01 NUC A 1 K4 A5 I6 A7 R8 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 K4 A5 I6 A7 R8 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 Q72I09 23824292 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4l6j S 3.40 BS02 MG S 1 A89 R92 A89 R92 Q72I09 23824292 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4l6j S 3.40 BS03 MG S 2 A56 N57 N61 A56 N57 N61 Q72I09 23824292 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4l6j T 3.40 BS01 NUC A 1 T3 S14 K16 K25 H31 K33 T35 K36 T37 E38 N41 K50 K53 N55 T56 L57 H58 R60 K62 K64 R65 L66 R68 Y69 L70 G71 K72 R73 P74 D75 K77 K78 T1 S12 K14 K23 H29 K31 T33 K34 T35 E36 N39 K48 K51 N53 T54 L55 H56 R58 K60 K62 R63 L64 R66 Y67 L68 G69 K70 R71 P72 D73 K75 K76 Q72I06 23824292 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEG 4l6j U 3.40 BS01 NUC A 1 R2 V7 K9 S17 G18 K19 V30 P32 K33 K34 Y35 I44 V45 K46 K47 V49 S52 P53 F60 H68 S70 K71 R73 R84 V85 R1 V6 K8 S16 G17 K18 V29 P31 K32 K33 Y34 I43 V44 K45 K46 V48 S51 P52 F59 H67 S69 K70 R72 R83 V84 Q72I15 23824292 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAK 4l6j V 3.40 BS01 NUC A 1 K46 R80 Q118 I146 G147 D148 S149 H151 E169 T170 V175 K44 R78 Q116 I144 G145 D146 S147 H149 E167 T168 V173 Q72IA7 23824292 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEAAA 4l6j V 3.40 BS02 NUC B 1 R10 P15 R19 R20 V27 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R8 P13 R17 R18 V25 Y27 N28 R29 N32 K34 R70 Q71 N73 R77 E82 H83 D85 F87 Q72IA7 23824292 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEAAA 4l6j V 3.40 BS03 MG B 2 Y29 D87 Y27 D85 Q72IA7 23824292 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEAAA 4l6j W 3.40 BS01 NUC A 1 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 G28 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 F69 L75 R77 N3 R5 D6 S7 Q8 A9 K10 R11 V14 K15 R16 Y17 E18 G19 Q20 R23 A24 G25 N26 I27 R30 R32 G33 T34 R35 G45 R46 D47 F48 T49 F51 F60 L66 R68 Q72HR3 23824292 TKNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4l6j W 3.40 BS02 NUC B 1 Q70 R72 R74 L75 Q61 R63 R65 L66 Q72HR3 23824292 TKNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4l6j X 3.40 BS01 NUC A 1 S8 N16 I18 Q19 R20 R21 K23 K25 R26 G29 G31 K32 K33 T34 T35 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 A64 S65 H66 K69 R76 G79 R81 K92 S1 N9 I11 Q12 R13 R14 K16 K18 R19 G22 G24 K25 K26 T27 T28 S31 K32 R33 R34 Q35 Y36 P37 N38 Q40 K41 R43 A57 S58 H59 K62 R69 G72 R74 K85 Q72G84 23824292 SGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLRLEGLSPKEIKKELL 4l6j X 3.40 BS03 MG X 2 S17 Q19 R41 S10 Q12 R34 Q72G84 23824292 SGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLRLEGLSPKEIKKELL 4l6j X 3.40 BS04 MG X 3 R50 E57 R43 E50 Q72G84 23824292 SGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLRLEGLSPKEIKKELL 4l6j Y 3.40 BS02 MG Y 1 A58 T62 A58 T62 Q72I12 23824292 MKLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLT 4l6j 2 3.40 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 D17 A18 R19 R20 S21 H22 H23 I29 V31 P32 P42 H43 Y51 Y52 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 D16 A17 R18 R19 S20 H21 H22 I28 V30 P31 P41 H42 Y50 Y51 P62652 23824292 AKHPVPKKKTSKARRDARRSHHALTPPILVPCPECKAMKPPHTVCPECGYYA 4l6j 3 3.40 BS01 NUC A 1 R19 Y21 T23 E24 K25 K27 T30 N32 E35 R37 K38 Y39 W42 K45 H46 R11 Y13 T15 E16 K17 K19 T22 N24 E27 R29 K30 Y31 W34 K37 H38 Q72GW3 23824292 LLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREV 4l6j 3 3.40 BS02 MG 3 1 K25 K27 K17 K19 Q72GW3 23824292 LLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREV 4l6j 4 3.40 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 T15 H16 G17 F18 R19 R21 M22 P25 G26 G27 R28 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41 R47 K48 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 T15 H16 G17 F18 R19 R21 M22 P25 G26 G27 R28 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41 R47 K48 P80340 23824292 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4l6j 4 3.40 BS02 MG 4 1 G17 F18 T43 P44 G17 F18 T43 P44 P80340 23824292 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4l6j 4 3.40 BS03 MG 4 2 K32 R35 Q36 K32 R35 Q36 P80340 23824292 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4l6j 4 3.40 BS04 MG 4 3 A13 K14 A20 R23 A13 K14 A20 R23 P80340 23824292 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRK 4l6j 5 3.40 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 Q35 S37 K39 I41 R42 Q43 K44 K47 F48 L50 K52 P53 E56 K59 L62 P63 Y64 P1 K2 M3 K4 T5 H6 K7 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 Q34 S36 K38 I40 R41 Q42 K43 K46 F47 L49 K51 P52 E55 K58 L61 P62 Y63 Q72L77 23824292 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPY 4l6k B 3.40 BS01 NUC A 1 K22 W24 P26 G99 G100 T103 N104 T107 R111 K133 Y148 R175 E176 K179 K16 W18 P20 G93 G94 T97 N98 T101 R105 K127 Y142 R169 E170 K173 P62662 23824292 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4l6k C 3.40 BS01 NUC A 1 G2 N3 K4 I5 F10 K26 R127 S154 G155 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 F186 R190 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 K25 R126 S153 G154 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 F185 R189 T191 Y192 G193 V194 G196 K198 P62663 23824292 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4l6k D 3.40 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 R35 R36 Y38 P40 G41 Q42 H43 Q45 S52 L58 R59 K61 Q62 R66 E72 R73 Q74 N77 K84 K85 K86 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 R141 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 R34 R35 Y37 P39 G40 Q41 H42 Q44 S51 L57 R58 K60 Q61 R65 E71 R72 Q73 N76 K83 K84 K85 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 R140 L154 E155 E204 S207 R208 P62664 23824292 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4l6k E 3.40 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y60 Y61 G85 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 L123 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y56 Y57 G81 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 L119 S121 R122 N123 I125 N126 Y129 P62665 23824292 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 4l6k G 3.40 BS01 NUC A 1 A2 R3 R4 R5 R6 A7 R10 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 I42 R76 R78 R79 V80 R94 R95 S98 R102 N109 R114 R115 A116 R119 A1 R2 R3 R4 R5 A6 R9 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 I41 R75 R77 R78 V79 R93 R94 S97 R101 N108 R113 R114 A115 R118 P62667 23824292 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4l6k H 3.40 BS01 NUC A 1 M1 L2 T3 A7 D8 T11 R12 R14 N15 V19 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 V129 G130 E132 M1 L2 T3 A7 D8 T11 R12 R14 N15 V19 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 S113 T114 S115 G128 V129 G130 E132 P62668 23824292 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4l6k I 3.40 BS01 NUC A 1 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 R20 Y36 Q38 G39 L40 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 R19 Y35 Q37 G38 L39 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P62669 23824292 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGRFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4l6k J 3.40 BS01 NUC A 1 R5 R9 H13 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 R46 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 E61 H62 H68 R70 D73 R3 R7 H11 S33 G34 P35 I36 P37 L38 P39 T40 R41 V42 R43 R44 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 E59 H60 H66 R68 D71 P62653 23824292 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4l6k K 3.40 BS01 NUC A 1 K11 Y20 S24 N26 N27 I29 T31 G37 N38 P39 I40 W42 S44 G46 V47 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 K1 Y10 S14 N16 N17 I19 T21 G27 N28 P29 I30 W32 S34 G36 V37 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P62654 23824292 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKK 4l6k L 3.40 BS01 NUC A 1 P4 T5 I6 N7 Q8 L9 R11 R14 E15 K16 V17 K20 S21 K22 K27 G28 P30 F31 R32 R33 K45 K46 N48 S49 A50 L51 R52 K53 T60 Y68 G71 E72 G73 R85 G86 R88 V89 K90 D91 R96 V100 V103 R112 K113 K114 S115 R116 S117 K118 Y119 G120 T121 K122 K123 P1 T2 I3 N4 Q5 L6 R8 R11 E12 K13 V14 K17 S18 K19 K24 G25 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 G68 E69 G70 R82 G83 R85 V86 K87 D88 R93 V97 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 P61941 23824292 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPK 4l6k M 3.40 BS01 NUC A 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 L70 N77 I78 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 L69 N76 I77 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P62655 23824292 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVA 4l6k N 3.40 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 F16 K17 V18 R19 Y21 T22 R23 C27 R29 A30 R31 S32 V33 Y34 R35 R41 I42 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 F15 K16 V17 R18 Y20 T21 R22 C26 R28 A29 R30 S31 V32 Y33 R34 R40 I41 R44 E45 K57 S59 W60 P62656 23824292 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4l6k O 3.40 BS01 NUC A 1 P2 K8 Q9 I12 F18 G20 D21 T22 G23 S24 T25 Q28 L31 R35 R38 L39 H42 H46 K48 D49 H50 H51 S52 H53 R54 G55 M58 M59 G61 R64 R65 R68 Y69 R72 P1 K7 Q8 I11 F17 G19 D20 T21 G22 S23 T24 Q27 L30 R34 R37 L38 H41 H45 K47 D48 H49 H50 S51 H52 R53 G54 M57 M58 G60 R63 R64 R67 Y68 R71 P62657 23824292 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4l6k P 3.40 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 T45 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 T45 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 P62238 23824292 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQE 4l6k Q 3.40 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T18 R25 L31 Y32 K34 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 K87 R91 R92 N94 Y95 S97 L98 S99 K100 P1 K2 S11 K13 M14 Q15 K16 T17 R24 L30 Y31 K33 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 K86 R90 R91 N93 Y94 S96 L97 S98 K99 P62658 23824292 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYQSLSK 4l6k S 3.40 BS01 NUC A 1 S4 L5 K6 F10 H14 W34 R36 R37 Y52 N53 G54 K55 G72 E73 T77 R78 T79 R81 S1 L2 K3 F7 H11 W31 R33 R34 Y49 N50 G51 K52 G69 E70 T74 R75 T76 R78 P62660 23824292 SLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR 4l6k T 3.40 BS01 NUC A 1 R8 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 A28 K29 S31 A32 K34 T35 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 K81 S82 R83 M85 R86 R89 G101 G102 G103 L104 S105 R1 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 A21 K22 S24 A25 K27 T28 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 K74 S75 R76 M78 R79 R82 G94 G95 G96 L97 S98 P62661 23824292 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAVQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4l6l I 3.40 BS01 NUC A 1 N11 K22 G24 Y25 N28 Y29 R33 S42 K45 A46 A49 R50 N11 K22 G24 Y25 N28 Y29 R33 S42 K45 A46 A49 R50 Q72GV5 23824292 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGITIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVV 4l6m B 3.40 BS01 NUC A 1 K22 W24 P26 L98 G99 G100 T103 N104 T107 R111 K133 K147 I172 R175 E176 K179 K16 W18 P20 L92 G93 G94 T97 N98 T101 R105 K127 K141 I166 R169 E170 K173 P62662 23824292 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4l6m D 3.40 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 E72 R73 Q74 N77 K84 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 K151 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 E71 R72 Q73 N76 K83 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 K150 E155 E204 S207 R208 P62664 23824292 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4l6m D 3.40 BS02 ZN D 1 C9 L21 K22 C26 C31 C8 L20 K21 C25 C30 P62664 23824292 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4l6m E 3.40 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 F45 K47 K57 Y61 G85 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 F41 K43 K53 Y57 G81 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 P62665 23824292 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 4la6 A 2.00 BS02 LA6 A 1 M190 E193 D197 Y278 R300 N303 N304 F305 C308 N345 S349 K352 E353 R433 Y434 M75 E78 D82 Y163 R185 N188 N189 F190 C193 N230 S234 K237 E238 R318 Y319 4.2.3.118 Q9F1Y6 23844678 GRAVPGLYHHPVPEPDPVRVEEVSRRIKRWAEDEVQLYPEEWEGQFDGFSVGRYMVGCHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPVGLGGRLLLAHTAIDHFHSTAEYTPTWQASLAADAPRRAYDSAMGYFVRAATPSQSDRYRHDMARLHLGYLAEGAWAQTGHVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHARPDMQRVIALAGNATTIVNDLYSYTKELNSPGRHLNLPVVIAEREQLCERDAYLKAVEVHNELQHSFEAAAADLAEACPLPPVLRFLRGVAAWVDGNHDWHRTNTYRYSLPDFW 4lck A 3.20 BS01 NUC C 1 I14 G15 T16 K17 Q18 D38 M62 V73 G74 A75 A76 I13 G14 T15 K16 Q17 D37 M61 V72 G73 A74 A75 P46350 SYDKVSQAKSIIIGTKQTVKALKRGSVKEVVVAKDADPILTSSVVSLAEDQGISVSMVESMKKLGKACGIEVGAAAVAIIL 4lck D 3.20 BS01 NUC F 1 I14 G15 Q18 D38 L41 M62 V73 G74 A75 A76 I13 G14 Q17 D37 L40 M61 V72 G73 A74 A75 P46350 SYDKVSQAKSIIIGTKQTVKALKRGSVKEVVVAKDADPILTSSVVSLAEDQGISVSMVESMKKLGKACGIEVGAAAVAIIL 4lr7 C 2.10 BS04 MN C 4 D214 D243 D212 D241 5.4.2.7 Q818Z9 KYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTAADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lr8 A 2.00 BS04 HSX A 1 S131 G132 Y152 A154 D156 Q160 R193 R197 R208 S130 G131 Y151 A153 D155 Q159 R192 R196 R207 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTAADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lr8 A 2.00 BS05 HSX A 2 T85 D156 R193 V283 D286 A287 H339 T84 D155 R192 V282 D285 A286 H338 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTAADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lr9 A 2.10 BS04 1X4 A 1 S131 G132 A154 R197 R208 S130 G131 A153 R196 R207 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTAADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lrb A 2.00 BS04 1X4 A 1 S131 G132 Q160 I195 R197 R208 S130 G131 Q159 I194 R196 R207 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTGADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lrd A 1.78 BS01 MN A 1 T85 D286 H291 H339 T84 D285 H290 H338 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSIGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTSADSLLQIAAHEEVVPLDELYKICKIARELTLDEKYKVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lre A 2.10 BS04 1X4 A 1 S131 G132 Y152 Q160 I195 R197 R208 S130 G131 Y151 Q159 I194 R196 R207 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTSADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lrf A 2.00 BS04 HSX A 1 G132 Y152 Q160 I195 R197 R208 G131 Y151 Q159 I194 R196 R207 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTGADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lrf A 2.00 BS05 HSX A 2 T85 D156 K240 V283 D286 A287 H339 T84 D155 K239 V282 D285 A286 H338 5.4.2.7 Q818Z9 NKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLQMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTGADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFAKLKEDDLLLITADHGNDPIHPGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNEL 4lrh A 2.80 BS01 FOL A 1 Y60 D81 Y85 Q100 W102 R103 R106 W134 H135 K136 G137 W138 W140 W171 S174 Y175 Y53 D74 Y78 Q93 W95 R96 R99 W127 H128 K129 G130 W131 W133 W164 S167 Y168 P15328 23851396 RTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGT