2m8d B BS01 NUC A 1 M106 P108 R109 G110 R111 Y112 G113 P115 S116 R117 S133 W134 Q135 D136 K138 D139 Y149 A150 D151 Y153 R154 H183 E184 M1 P3 R4 G5 R6 Y7 G8 P10 S11 R12 S28 W29 Q30 D31 K33 D34 Y44 A45 D46 Y48 R49 H78 E79 Q07955 MAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDG 2m9w A BS01 ZN A 1 C13 C16 C34 C37 C13 C16 C34 C37 P43694 SHMSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRK 2ymt A 1.80 BS01 III B 1 Q714 A715 A716 V717 P718 K719 L723 L725 R756 K758 L759 R760 Q51 A52 A53 V54 P55 K56 L60 L62 R93 K95 L96 R97 O75843 SAPIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ 2yoz A 2.10 BS01 OVE A 1 Y168 H230 T232 F235 H309 T311 P320 V321 T323 Y8 H63 T65 F68 H142 T144 P153 V154 T156 3.1.4.37 P16330 EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 2yp0 A 2.30 BS02 OVE A 2 R203 H204 K356 R41 H42 K188 3.1.4.37 P16330 DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 2ypc A 1.89 BS01 QQX A 1 Y168 H230 T232 F235 R307 T311 P320 V321 Y6 H68 T70 F73 R145 T149 P158 V159 3.1.4.37 P16330 DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRASVTLGCAADVQPVQTGLDLLDILQQVKSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 2yph A 2.10 BS01 QQY A 1 Y168 T232 F235 H309 T311 P320 V321 Y6 T66 F69 H143 T145 P154 V155 3.1.4.37 P16330 DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGEKLELVSYFGKRPPGVLSCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 2yq9 A 1.90 BS01 2AM A 1 Y168 H230 T232 F235 H309 T311 P320 A321 T323 G324 Y7 H65 T67 F70 H144 T146 P155 A156 T158 G159 3.1.4.37 P16330 KDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPAQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 3vur A 1.36 BS01 GTS A 1 Y7 F8 A12 L13 W38 K42 Q49 M50 P51 Q62 S63 Y7 F8 A12 L13 W38 K42 Q49 M50 P51 Q62 S63 2.5.1.18 0016740 Q5CCJ4 PNVKFYYFPVKALGESQRLLLAYGGQEFEDNRISSENWPEFKPKTPFGQMPVLEIDGKQYAQSTAICRYLGRKYGLAGANDEEAFEIDQNVEFLNDIRASAASVHYEKDEAVKAKKKAELEETKYPFFFEKLNEILTKNNGHIALGKLTWGDFVYAGMYDYLKAMLQKPDLEQKYPAFRKPIEAVLAIPKVKAYVDAAPRTEL 3vz3 A 1.69 BS01 SSN A 1 N131 F132 W135 Q136 R139 S261 A262 I263 S419 N130 F131 W134 Q135 R138 S260 A261 I262 S418 B1XMM6 23500184 AIATINPTTGEICQRFKALTPAEIDAKLAKAQEAFQAYRRTSFSQRRQWLENAAAILERDTSKFAEIMTTEMGKTHQSAIAEAEKSALVCRYYAEHGEQFLANEYTETQATESYVCYQPLGILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAAGFPEGVFQTLLIGASQVEQVIKDPRVKAATLTGSEPAGASLASLAGQEIKPTLLELGGSDPFVVFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKIGDPMAPETDIGPLATEGILQDISRQVDQAVAAGAKILLGGRPLDRAGYFYPPTILTEIPPGAKILQEELFAPVAMVFTVKDLDQAIALANDIPFGLGASAWTNDPAEQQRFIQELDAGAVFINGMVKSDPRLPFGGTKRSGYGRELGLAGIRTFVNAKTVWLK 3vz3 A 1.69 BS02 NAP A 1 V127 M128 W130 N131 Q136 R139 K154 H155 A156 S157 A187 V190 T205 G206 S207 A210 E228 L229 G230 A262 E359 F361 L387 F425 V126 M127 W129 N130 Q135 R138 K153 H154 A155 S156 A186 V189 T204 G205 S206 A209 E227 L228 G229 A261 E358 F360 L386 F424 B1XMM6 23500184 AIATINPTTGEICQRFKALTPAEIDAKLAKAQEAFQAYRRTSFSQRRQWLENAAAILERDTSKFAEIMTTEMGKTHQSAIAEAEKSALVCRYYAEHGEQFLANEYTETQATESYVCYQPLGILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAAGFPEGVFQTLLIGASQVEQVIKDPRVKAATLTGSEPAGASLASLAGQEIKPTLLELGGSDPFVVFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKIGDPMAPETDIGPLATEGILQDISRQVDQAVAAGAKILLGGRPLDRAGYFYPPTILTEIPPGAKILQEELFAPVAMVFTVKDLDQAIALANDIPFGLGASAWTNDPAEQQRFIQELDAGAVFINGMVKSDPRLPFGGTKRSGYGRELGLAGIRTFVNAKTVWLK 3w51 A 2.00 BS01 AJ2 A 1 H1031 G1032 Y1050 Y1060 S1068 Y1071 I1075 E1138 H80 G81 Y99 Y109 S117 Y120 I124 E186 2.4.2.30 Q9H2K2 23672613 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 3w5w A 2.95 BS01 5GP A 1 R105 K287 S289 R291 G308 G309 G310 S315 G316 G317 R104 K284 S286 R288 G305 G306 G307 S312 G313 G314 0030145,0003676,0016787 Q64PD9 LTKVIAQAHIDHFTKWFERADKIVIVSHVSPDGDAIGSSLGLYHFLDSQDKIVNVIVPNAFPDFLKWMPGSKDILLYDRYQEFADKLIMEADVICCLDFNALKRIDEMSDIVAASPGRKIMIDHHLYPEDFCRITISHPEISSTSELVFRLICRMGYFSDISKEGAECIYTGMMTDTGGFTYNSNNREIYFIISELLSKGIDKDDIYRKVYNTYSESRLRLMGYVLSNMKVYKDYNSALISLTKEEQGKFDYIKGDSEGFVNIPLSIKNVCFSCFLREDTEMIKISLRSVGKFPCNRLAAEFFNGGGHLNASGGEFYGTMEEAVKVFEQALEKYKPLLKE 3w5w A 2.95 BS02 MN A 1 H29 D33 D99 H28 D32 D98 0030145,0003676,0016787 Q64PD9 LTKVIAQAHIDHFTKWFERADKIVIVSHVSPDGDAIGSSLGLYHFLDSQDKIVNVIVPNAFPDFLKWMPGSKDILLYDRYQEFADKLIMEADVICCLDFNALKRIDEMSDIVAASPGRKIMIDHHLYPEDFCRITISHPEISSTSELVFRLICRMGYFSDISKEGAECIYTGMMTDTGGFTYNSNNREIYFIISELLSKGIDKDDIYRKVYNTYSESRLRLMGYVLSNMKVYKDYNSALISLTKEEQGKFDYIKGDSEGFVNIPLSIKNVCFSCFLREDTEMIKISLRSVGKFPCNRLAAEFFNGGGHLNASGGEFYGTMEEAVKVFEQALEKYKPLLKE 3w5w A 2.95 BS03 MN A 2 D35 D99 H125 H126 D177 D34 D98 H124 H125 D176 0030145,0003676,0016787 Q64PD9 LTKVIAQAHIDHFTKWFERADKIVIVSHVSPDGDAIGSSLGLYHFLDSQDKIVNVIVPNAFPDFLKWMPGSKDILLYDRYQEFADKLIMEADVICCLDFNALKRIDEMSDIVAASPGRKIMIDHHLYPEDFCRITISHPEISSTSELVFRLICRMGYFSDISKEGAECIYTGMMTDTGGFTYNSNNREIYFIISELLSKGIDKDDIYRKVYNTYSESRLRLMGYVLSNMKVYKDYNSALISLTKEEQGKFDYIKGDSEGFVNIPLSIKNVCFSCFLREDTEMIKISLRSVGKFPCNRLAAEFFNGGGHLNASGGEFYGTMEEAVKVFEQALEKYKPLLKE 3zbr A 2.30 BS01 NAP A 1 L167 Y168 P226 T232 F235 H309 T311 P320 V321 Y376 G378 L7 Y8 P63 T69 F72 H146 T148 P157 V158 Y213 G215 3.1.4.37 P16330 EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEKLELVSYFGKRPPGVLSCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 3zbr B 2.30 BS01 NAP B 1 L167 P226 T232 F235 H309 T311 P320 V321 Y376 L7 P62 T68 F71 H142 T144 P153 V154 Y209 3.1.4.37 P16330 EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDKLELVSYFGKRPPGVLSCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDLSASEGLPPGSRAHVTLGCAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 3zbs A 2.45 BS01 OVE A 1 Y168 H230 T232 F235 H309 T311 P320 A321 T323 Y6 H64 T66 F69 H140 T142 P151 A152 T154 3.1.4.37 P16330 DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGEKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDPSASEGLPPGSRAHVTLGCAADVQPAQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 3zbz A 2.10 BS01 OVE A 1 Y168 H230 T232 F235 H309 T311 P320 A321 Y6 H63 T65 F68 H139 T141 P150 A151 3.1.4.37 P16330 DFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGKLELVSYFGKRPPGVLHCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKLSISALFVTPKTAGAQVVLTDQELQLWPSDPSASEGLPPGSRAHVTLGCAADVQPAQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSLTKKMEVKAIFTGYYG 3zd8 A 2.00 BS01 K A 1 L171 A172 G173 P180 G181 V182 A183 G184 I185 L159 A160 G161 P168 G169 V170 A171 G172 I173 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR 3zd9 A 2.00 BS01 K A 1 L171 A172 G173 P180 G181 V182 A183 I185 L170 A171 G172 P179 G180 V181 A182 I184 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zda A 1.50 BS01 NUC B 1 A183 G184 G186 P187 K188 S189 A180 G181 G183 P184 K185 S186 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zda A 1.50 BS02 K A 1 L171 A172 G173 P180 G181 V182 A183 G184 I185 G186 L168 A169 G170 P177 G178 V179 A180 G181 I182 G183 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zda A 1.50 BS03 PIV A 1 Q35 L36 H39 R141 Y143 K146 Q34 L35 H38 R138 Y140 K143 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zdb A 1.47 BS01 NUC X 1 S175 G184 I185 G186 P187 K188 S189 S171 G180 I181 G182 P183 K184 S185 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zdb A 1.47 BS03 MG A 1 A172 I185 A168 I181 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zdc A 1.53 BS01 NUC X 1 A183 G184 I185 G186 P187 K188 S189 A180 G181 I182 G183 P184 K185 S186 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDESSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zdc A 1.53 BS03 CA A 1 A172 I185 G186 A169 I182 G183 3.1.-.- Q8X6R9 AVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDESSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLV 3zhf A 1.70 BS01 III B 1 Q714 A715 A716 V717 P718 K719 S720 R756 K758 Q52 A53 A54 V55 P56 K57 S58 R94 K96 O75843 GSAPIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ 3zj4 A 3.10 BS01 HEM A 1 R99 V100 V101 H102 R139 G158 V173 G174 N175 F180 A185 F188 I248 H249 F365 L381 R385 S388 Y389 T392 Q393 R396 R63 V64 V65 H66 R103 G122 V137 G138 N139 F144 A149 F152 I212 H213 F329 L345 R349 S352 Y353 T356 Q357 R360 1.11.1.6 0016491,0055114,0046872,0004096,0042744,0004601 Q9C169 VDARQRLKEVEVDDNGQFMTTDFGGNIEEQFSLKAGGRGSTLLEDFIFRQKLQHFDHERIPERVVHARGAGAHGIFTSYGDWSNITAASFLGAKDKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIRFPDLIHSVKPSPDNEVPQAATAHDSAWDFFSSQPSALHTLFWAMSGNGIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAALVWEEAQVLAGKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKFLPEEFAPLQVLGEMTLNRNPMNYFAETEQISFQPGHIVRGVDFTEDPLLQGRLYSYLDTQLNRHRGPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNIHHYSPSYLNKGYPAQANQTVGRGFFTTPGRTASGVLNRELSATFDDHYTQPRLFFNSLTPVEQQFVINAIRFEASHVTNEQVKKNVLEQLNKISNDVAKRVAVALGLEAPQPDPTYYHNNVTRGVSIFNESLPTIATLRVGVLSTTKGGSLDKAKALKEQLEKDGLKVTVIAEYLASGVDQTYSAADATAFDAVVVAEGAERVFSGKGAMSPLFPAGRPSQILTDGYRWGKPVAAVGSAKKALQSIGVEEKEAGVYAGAQDEVIKGVEEGLKVFKFLERFAVDGD 3zni A 2.21 BS01 III B 1 Y266 R286 S288 C289 T290 R291 Y299 Q308 T309 P311 E326 F328 Y329 Y229 R249 S251 C252 T253 R254 Y262 Q271 T272 P274 E289 F291 Y292 6.3.2.19 Q13191 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFD 3zni A 2.21 BS02 ZN A 1 C373 C376 C393 C396 C336 C339 C356 C359 6.3.2.19 Q13191 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFD 3zni A 2.21 BS03 ZN A 2 C388 H390 C408 C411 C351 H353 C371 C374 6.3.2.19 Q13191 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFD 3zni A 2.21 BS04 CA A 1 D221 T223 N225 Y227 E232 D184 T186 N188 Y190 E195 6.3.2.19 Q13191 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFD 3zni E 2.21 BS01 III F 1 Y266 R286 S288 C289 T290 R291 Y299 Q308 T309 I310 P311 K314 F328 Y329 Y229 R249 S251 C252 T253 R254 Y262 Q271 T272 I273 P274 K277 F291 Y292 6.3.2.19 Q13191 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFD 3zni M 2.21 BS01 III N 1 Y266 R286 S288 C289 T290 R291 Q308 T309 I310 P311 E326 F328 Y329 Y229 R249 S251 C252 T253 R254 Q271 T272 I273 P274 E289 F291 Y292 6.3.2.19 Q13191 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQFELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFD 4apd A BS01 D6M A 1 A25 K26 F28 I29 W31 L32 V33 A19 K20 F22 I23 W25 L26 V27 HAEGTFTSDVSSYLEGQAAKEFIAWLVRGRG 4ayu A 1.50 BS04 NAG A 1 Q31 N32 S101 Q31 N32 S101 0046872,0006461,0043234,0051131,0005615,0006457,0051082,0006953,0031012,0005576 P02743 HTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV 4ayu B 1.50 BS04 NAG B 1 Q31 N32 E99 S101 Q31 N32 E99 S101 0006953,0043234,0006461,0031012,0051131,0005615,0051082,0006457,0005576,0046872 P02743 HTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV 4az5 A 1.73 BS01 NGW A 1 R196 H297 D360 E361 F415 W439 Y469 V471 Y482 W517 D519 R16 H117 D180 E181 F235 W259 Y289 V291 Y302 W337 D339 3.2.1.52 P49610 NEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTP 4az6 A 1.36 BS01 OAN A 1 R196 H297 D360 E361 F415 W439 W443 Y469 V471 W481 Y482 W517 D519 R18 H119 D182 E183 F237 W261 W265 Y291 V293 W303 Y304 W339 D341 3.2.1.52 P49610 SHNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLT 4az7 A 1.70 BS02 LOG A 2 N279 Y280 D283 K284 N99 Y100 D103 K104 3.2.1.52 P49610 NEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLT 4azb A 2.10 BS01 OAN A 1 R196 H297 D360 E361 F415 W439 D466 Y469 V471 W517 D519 R16 H117 D180 E181 F235 W259 D286 Y289 V291 W337 D339 3.2.1.52 P49610 NEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGGGNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDAIRSLDSNLSRAQQDTIDQAIAKLQE 4azc A 2.09 BS01 NGW A 1 R641 H742 D804 E805 F849 W872 Y902 I904 W951 D953 R19 H120 D182 E183 F227 W250 Y280 I282 W329 D331 P49610 GSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPTGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGK 4azc A 2.09 BS05 MG A 4 Y854 Q862 K865 K890 Y232 Q240 K243 K268 P49610 GSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPTGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGK 4azc C 2.09 BS03 MG C 2 Q823 L824 Y825 G826 Q201 L202 Y203 G204 P49610 GSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPTNGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQG 4azg A 2.40 BS01 OAN A 1 R641 H742 D804 E805 A813 F849 W872 W876 Y879 Y902 I904 W951 D953 R20 H121 D183 E184 A192 F228 W251 W255 Y258 Y281 I283 W330 D332 3.2.1.52 P49610 RGSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKISKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQ 4azi A 1.98 BS01 OAN A 1 R641 H742 D804 E805 F849 W872 Y879 Y902 I904 Y914 W951 D953 R19 H120 D182 E183 F227 W250 Y257 Y280 I282 Y292 W329 D331 3.2.1.52 P49610 GSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGWYFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAA 4azi B 1.98 BS01 OAN B 1 R641 H742 D804 E805 A813 F849 W872 Y879 Y902 I904 W913 Y914 W951 D953 R19 H120 D182 E183 A191 F227 W250 Y257 Y280 I282 W291 Y292 W329 D331 3.2.1.52 P49610 GSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGWYFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQ 4b09 A 3.30 BS01 TBR A 1 G43 D44 L47 D68 M71 L72 E75 G35 D36 L39 D60 M63 L64 E67 P69229 NTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLMLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRSPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV 4b09 B 3.30 BS01 TBR B 1 L64 P65 T67 D68 L56 P57 T59 D60 P69229 NTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLMLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV 4b09 D 3.30 BS01 TBR D 1 L64 P65 G66 D68 L56 P57 G58 D60 P69229 NTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLMLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV 4b09 E 3.30 BS01 TBR E 1 D44 L47 D68 M71 L72 E75 D36 L39 D60 M63 L64 E67 P69229 NTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLMLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRSPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV 4b09 G 3.30 BS01 TBR G 1 G43 D44 L47 M71 L72 E75 G35 D36 L39 M63 L64 E67 P69229 NTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLMLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRSPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV 4b0n A 2.85 BS01 ACD A 1 A62 Y83 R91 F93 F98 T163 C194 S224 H227 T228 F230 H240 F243 I282 L284 I291 T292 C293 L295 L366 A27 Y48 R56 F58 F63 T128 C159 S189 H192 T193 F195 H205 F208 I247 L249 I256 T257 C258 L260 L331 2.3.1.- D8LJ35 KDEQTVYPVIAGMAIGNPQYRCTQNEALAVASKCPGLESIKPVLERIYGNSRIGSRYFAVPDFTPGRAAKGDPLFYPADGSYQVPVDVRLDKFKEKAVPLVSDVARRAIKEAGLNVEDISKLVVVSSTGFLGPGLDCELIKNLGLTRSVDRTLIGFMGCAAAMNGFRNANDYVTANPGKYALMICVELSSVHTTFDDNINDAILHAIFADGCAAAVLKGARKSECPKGTLAIVDNHAWLMEGTEDGITLAIKPNGITCTLSKFLPQYIAKNIAFFADGFLKKHKLGRDDVDFWCVHPGGRRIIEEAQNGLGLSEEQTADSWAVLGEYGNMLSPSVMFVLSRVFKRHNAALAQGKPGYQTGMAFSFSPGVGAEGILLRQI 4b0n B 2.85 BS01 ACD B 1 Y83 R91 F93 F98 C194 S224 T228 F230 H240 F243 L284 I291 C293 L366 Y48 R56 F58 F63 C159 S189 T193 F195 H205 F208 L249 I256 C258 L331 2.3.1.- D8LJ35 KDEQTVYPVIAGMAIGNPQYRCTQNEALAVASKCPGLESIKPVLERIYGNSRIGSRYFAVPDFTPGRAAKGDPLFYPADGSYQVPVDVRLDKFKEKAVPLVSDVARRAIKEAGLNVEDISKLVVVSSTGFLGPGLDCELIKNLGLTRSVDRTLIGFMGCAAAMNGFRNANDYVTANPGKYALMICVELSSVHTTFDDNINDAILHAIFADGCAAAVLKGARKSECPKGTLAIVDNHAWLMEGTEDGITLAIKPNGITCTLSKFLPQYIAKNIAFFADGFLKKHKLGRDDVDFWCVHPGGRRIIEEAQNGLGLSEEQTADSWAVLGEYGNMLSPSVMFVLSRVFKRHNAALAQGKPGYQTGMAFSFSPGVGAEGILLRQI 4b8l A 3.00 BS01 A0P A 1 L99 K101 G102 K103 V107 A120 K122 E171 F172 A173 E177 D234 L13 K15 G16 K17 V21 A34 K36 E85 F86 A87 E91 D148 2.7.11.1 Q6DE08 KFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKVIHRDIKPENLLMGYKGELKIADFTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVKANSRRVL 4b8m A 1.85 BS01 VX6 A 1 L99 V107 A120 K122 L170 E171 F172 A173 P174 R175 G176 E177 L223 A233 L13 V21 A34 K36 L84 E85 F86 A87 P88 R89 G90 E91 L137 A147 2.7.11.1 Q6DE08 KFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVKANSRRVLPPVYQS 4b8m B 1.85 BS01 VX6 B 1 L99 F104 V107 K122 L170 E171 F172 A173 P174 R175 G176 E177 L223 A233 D234 L22 F27 V30 K45 L93 E94 F95 A96 P97 R98 G99 E100 L146 A156 D157 2.7.11.1 Q6DE08 TALAEMPKRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALHYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGMPPFDSPSHTETHRRIVNVDLKFPPFLSDGSKDLISKLLRYHPPQRLPLKGVMEHPWVKANSRRVLPPVYQS 4b8s A 2.58 BS01 GLC A 1 N38 D42 E96 G119 G120 I124 H184 V447 D451 N37 D41 E95 G118 G119 I123 H183 V446 D450 2.7.1.147 0005975,0016301,0016740,0006096,0005737,0046872,0004340,0043843,0006006,0000287,0051156,0016310 Q7M537 23818958 KESLKDRIRLWKRLYVNAFENALNAIPNVKGVLLAYNTNIDAIKYLDKDDLEKRVTEIGKEKVFEIIENPPEKISSIEELLGGILRSIKLGKAMEWFVESEEVRRYLREWGWDELRIGGQAGIMANLLGGVYRIPTIVHVPQNPKLQAELFVDGPIYVPVFEGNKLKLVHPKDAIAEEEELIHYIYEFPRGFQVFDVQAPRENRFIANADDYNARVYMRREFREGFEEITRNVELAIISGLQVLKEYYPDGTTYRDVLDRVESHLNILNRYNVKSHFEFAYTANRRVREALVELLPKFTSVGLNEVELASIMEIIGDEELAKEVLEGHIFSVIDAMNVLMDETGIERIHFHTYGYYLALTQYRGEEVRDALLFASLAAAAKAMKGNLERIEQIRDALSVPTNERAIVLEEELEKEFTEFENGLIDMVDRQLAFVPTKIVASPKSTVGIGDTISSSAFVSEFGMRKR 4b8s A 2.58 BS02 AMP A 1 E203 N305 H352 T353 Y354 K438 I439 V440 P443 I449 G450 I453 E202 N304 H351 T352 Y353 K437 I438 V439 P442 I448 G449 I452 2.7.1.147 0005975,0016301,0016740,0006096,0005737,0046872,0004340,0043843,0006006,0000287,0051156,0016310 Q7M537 23818958 KESLKDRIRLWKRLYVNAFENALNAIPNVKGVLLAYNTNIDAIKYLDKDDLEKRVTEIGKEKVFEIIENPPEKISSIEELLGGILRSIKLGKAMEWFVESEEVRRYLREWGWDELRIGGQAGIMANLLGGVYRIPTIVHVPQNPKLQAELFVDGPIYVPVFEGNKLKLVHPKDAIAEEEELIHYIYEFPRGFQVFDVQAPRENRFIANADDYNARVYMRREFREGFEEITRNVELAIISGLQVLKEYYPDGTTYRDVLDRVESHLNILNRYNVKSHFEFAYTANRRVREALVELLPKFTSVGLNEVELASIMEIIGDEELAKEVLEGHIFSVIDAMNVLMDETGIERIHFHTYGYYLALTQYRGEEVRDALLFASLAAAAKAMKGNLERIEQIRDALSVPTNERAIVLEEELEKEFTEFENGLIDMVDRQLAFVPTKIVASPKSTVGIGDTISSSAFVSEFGMRKR 4bcx A 2.00 BS01 PDO A 1 Q714 R760 Q49 R95 O75843 PIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ 4frz A 2.40 BS01 ADP A 1 R897 P898 G973 S974 G975 K976 T977 F978 R12 P13 G88 S89 G90 K91 T92 F93 Q9FHN8 23805258 MKGKIRVYCRIRPLNEKESSEREKQMLTTVDEFTVEHPWKDDKRKQHIYDRVFDMRASQDDIFEDTKYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGHESNPGLTPRATKELFNILKRDSKRFSFSLKAYMVELYQDTLVDLLLPKSARRLKLEIKKDSKGMVFVENVTTIPISTLEELRMILERGSERRHVSGTNMNEESSRSHLILSVVIESIDLQTQSAARGKLSFVDLAGSERVKQSINKSLSALGDVIGALSSGNQHIPYRNHKLTMLMSDSLGGNAKTLMFVNVSPAESNLDETYNSLLYASRVRTIVNDPSKHISSKEMVRLKKLVAYWKEQAGKKGEEEDLVDIEEDR 4frz B 2.40 BS01 ADP B 1 R895 R897 P898 T972 G973 S974 G975 K976 T977 F978 R19 R21 P22 T96 G97 S98 G99 K100 T101 F102 Q9FHN8 23805258 KRYYNTIEDMKGKIRVYCRIRPLNEKESSEREKQMLTTVDEFTVEHPWKDDKRKQHIYDRVFDMRASQDDIFEDTKYLVQSAVDGYNVCIFAYGQTGSGKTFTIYGHESNPGLTPRATKELFNILKRDSKRFSFSLKAYMVELYQDTLVDLLLPKSARRLKLEIKKDSKGMVFVENVTTIPISTLEELRMILERGSERRHVESSRSHLILSVVIESIDLQTQSAARGKLSFVDLAGSERINKSLSALGDVIGALSSGNQHIPYRNHKLTMLMSDSLGGNAKTLMFVNVSPAESNLDETYNSLLYASRVRTIVNDPSKHISSKEMVRLKKLVAYWKEQAGKEDLVDIEED 4fz7 A 1.75 BS01 0VH A 1 L377 G378 A400 M448 E449 M450 A451 G454 P455 R498 N499 L501 D512 L15 G16 A36 M78 E79 M80 A81 G84 P85 R128 N129 L131 D142 2.7.10.2 0006468,0005515,0043306,0033630,0050764,0045579,0001820,0090237,0045425,0018108,0001525,0009887,0046638,0032928,0005524,0010543,0019048,0008283,0002283,0007166,0007257,0038096,0048514,0004715,0045087,0090330,0042101,0046641,0070372,0030168,0019370,0004672,0004713,0043366,0023014,0005886,0045401,0001945,0002281,0050853,0007596,0005829,0042742,0043313,0007167,0046777,0050715,0050850,0005178,0000166,0016310,0045780,0016740,0004716,0016301,0030593,0050731,0016020,0038095,0071226,0007229,0002250,0032009,0045588,0035556,0005737,0019815,0007159,0019901,0002366,0000187,0002554 P43405 VYLDRKLLTLEDKELGSFGTVKKGYYQMKKVVKTVAVKILPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNEGHH 4fz8 H 2.66 BS01 ZN L 1 H164 T183 H171 T190 EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGRGLEWVSSISNTSTYIYYADSVEGRFTLSRDNAKNSLYLQMNSLRAEDTAVYYCARANQHFDWLLSLLGGYHYYGMDVWGQGTTVTVSSASTKGPSVFGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS 4fz8 L 2.66 BS01 ZN L 1 N137 N138 N141 N142 DIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFIGSGSGTDFTLKISRVEAEDVGVFYCMQALQAVGFGPGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR 4gb0 A 2.60 BS01 ZN A 1 C31 H33 C51 C54 C29 H31 C49 C52 6.3.2.- Q8IYW5 23255131 LPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRAS 4gb0 A 2.60 BS02 ZN A 2 C16 C19 C36 C39 C14 C17 C34 C37 6.3.2.- Q8IYW5 23255131 LPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRAS 4gc9 A 2.10 BS01 SAM A 1 Q35 N36 F37 L38 G63 P64 G65 P66 V84 E85 K86 D87 F90 G110 D111 V112 N141 P143 V146 Q26 N27 F28 L29 G54 P55 G56 P57 V75 E76 K77 D78 F81 G101 D102 V103 N132 P134 V137 2.1.1.- Q8JZM0 23804760 FRLPPLPTIREIIKLFGLRAVKQLSQNFLLDLRLTDKIVRKAGSLADVYVYEVGPGPGGITRSILNANVAELLVVEKDTRFIPGLQMLSDAAPGKLRIVHGDVLTYKIEKAFPGNIRRQWEDDPPNVHIIGNLPFSVSTPLIIKWLENISLKDGPFVYGRTKMTLTFQKEVAERLVATTGSKQHSRLSIMAQYLCNVEHLFTIPGKAFVPKPKVDVGVVHLTPLIEPKIKQPFKLVEKVVQNAFQFRRKYCHRGLGMLFPEAQRLESTGRLLQLADIDPTLRPTHLSLMHFKSLCDVYRKMCDEDPQLFTYNFREELK 4gkv A 2.01 BS01 NAD A 1 C37 H38 T39 H42 C145 T149 G169 G171 G172 L173 D193 V194 Q198 T235 A236 V237 A241 V258 G259 L260 S282 L283 V284 M321 R329 C37 H38 T39 H42 C145 T149 G169 G171 G172 L173 D193 V194 Q198 T235 A236 V237 A241 V258 G259 L260 S282 L283 V284 M321 R329 1.1.1.1 P39451 MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDFRH 4gkv A 2.01 BS02 ZN A 1 C37 H58 C145 C37 H58 C145 1.1.1.1 P39451 MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDFRH 4gkv A 2.01 BS03 ZN A 2 C89 C92 C95 C103 C89 C92 C95 C103 1.1.1.1 P39451 MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDFRH 4gkv B 2.01 BS01 III P 1 Q223 D247 R271 L274 Q223 D247 R271 L274 1.1.1.1 P39451 MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDFRH 4gkv C 2.01 BS01 III P 1 F48 G49 W84 R104 S105 V106 N108 Y111 F48 G49 W84 R104 S105 V106 N108 Y111 1.1.1.1 P39451 MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDFRH 4gqi A 1.95 BS02 FAD A 1 H11 K15 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 E197 R200 K201 H11 K15 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 E197 R200 K201 1.10.99.2 0055114,0016491,0009055,0008753,0001512,0005634,0005730,0007613,0046872,0005737 P16083 23131339 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 4gqi A 1.95 BS05 M49 B 1 W105 G149 M154 N161 W105 G149 M154 N161 1.10.99.2 0055114,0016491,0009055,0008753,0001512,0005634,0005730,0007613,0046872,0005737 P16083 23131339 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 4gr9 B 2.29 BS03 FAD B 1 H11 K15 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 R200 H11 K15 S16 F17 N18 S20 P102 L103 Y104 W105 F106 T147 T148 G149 G150 Y155 E193 R200 1.10.99.2 0008753,0005737,0007613,0005730,0005634,0046872,0001512,0016491,0009055,0055114 P16083 23131339 AGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 4hdo B 1.67 BS02 GNP B 1 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 G60 N116 K117 D119 L120 S147 A148 K149 G13 V14 G15 K16 S17 A18 F28 V29 E30 Y32 P34 T35 G60 N112 K113 D115 L116 S143 A144 K145 0050796,0005911,0030054,0005886,0016020,0000166,0005811,0008283,0005829,0005622,0019003,0005515,0030168,0003924,0007596,0006112,0044281,0007264,0005525,2000114,0005737 P61224 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR 4hdq A 1.95 BS01 III C 1 L472 Q473 L474 K475 Y477 H478 H483 I490 E493 A638 F640 L721 L54 Q55 L56 K57 Y59 H60 H65 I72 E75 A220 F222 L303 O00522 YEKVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQL 4hnz A 2.39 BS01 MG A 1 T157 D160 S163 T157 D160 S163 3.4.25.- Q383Q5 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEH 4hnz C 2.39 BS01 MG C 1 T157 D160 V161 S163 T157 D160 V161 S163 3.4.25.- Q383Q5 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKLENKIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAMRIATDIDVFSNEHWDVEVLEH 4hxy A 1.68 BS01 NDP A 1 G191 G194 G195 L196 L216 S217 R218 Q219 V245 D246 V247 A273 A274 G275 A296 K297 S318 Y332 W358 G359 P360 W361 G365 M366 L367 G181 G184 G185 L186 L206 S207 R208 Q209 V235 D236 V237 A263 A264 G265 A286 K287 S308 Y322 W348 G349 P350 W351 G355 M356 L357 Q6V1M8 23790488 RTGWFSETWRQLGTADRVPGNWLLLGEVPPALGSLFDDPLTAASWDRSTAPDGVLVGAGAAEDLLAALHEVAGHPTGPVWCVTSRAVGVGTVDDPAADVRAAGVWGLGRVAGLELPDRWGGLVDLPERIDDATRRALAGTLTDGEDQLAVRDGQLWARRLVTTPAPQTGTWTPKGTVLITGGTGGLGGHVARRVAEQGSADRILLLSRQGSAAPGATELLEGIRAFGATAEAVAVDVTDRAAMSGLIDALAAEGAPVRTVVHAAGVVRDVRIAETGAEELAAQMAAKVEGALLLDELLPDLDDFVLFSSISGIWGAAGQAGYAAGNACLDALARRRREQGKRAVSVAWGPWAGGGMLTEHDERELRKRGLTPLLVPAALQAMEQAIMSDRAGDPVVADVTWSRFLPAFTASRPSPLFGSFEEKAA 4hxy B 1.68 BS02 ACA B 1 V277 S319 Q329 Y332 M366 L367 D371 V272 S314 Q324 Y327 M361 L362 D366 Q6V1M8 23790488 ARTGWFSETWRQLGRAATADRVPGNWLLLGEVPPALGSLFDDPLTAASWDRSTAPDGVLVGAGAAEDLLAALHEVAGHPTGPVWCVTSRAVGVGTVDDPAADVRAAGVWGLGRVAGLELPDRWGGLVDLPERIDDATRRALAGTLTDDGEDQLAVRDGQLWARRLVTTPAPQTGTWTPKGTVLITGGTGGLGGHVARRVAEQGSADRILLLSRQGSAAPGATELLEGIRAFGATAEAVAVDVTDRAAMSGLIDALAAEGAPVRTVVHAAGVVRDVRIAETGAEELAAQMAAKVEGALLLDELLPDLDDFVLFSSISGIWGAAGQAGYAAGNACLDALARRRREQGKRAVSVAWGPWAGGGMLTEHDERELRKRGLTPLLVPAALQAMEQAIMSDRAGDPVVADVTWSRFLPAFTASRPSPLFGSFEEKAA 4i5h A 1.90 BS01 G17 A 1 V37 A50 K52 E69 I81 I82 I101 D104 M106 D109 K112 H145 L154 L164 D165 V29 A42 K44 E61 I73 I74 I93 D96 M98 D101 K104 H137 L146 L156 D157 2.7.11.24 0019858,0031663,0006915,0032872,0051493,0072584,0090170,0030335,0019902,0031143,0050852,0050853,0060716,0045893,0007049,0016310,0005925,0031435,0000165,0033598,0070371,0005901,0016740,0006468,0004674,0005829,0005654,0008134,0035556,0043627,0001784,0015630,0000189,0045596,0016772,0019233,0007243,0008284,0009636,0016301,0005739,0000166,0004672,2000641,0005794,0005856,0005815,0043204,0008353,0018105,0032496,0005524,0005770,0004707,0005634,0005769,0007165,0032839,0043234,0009887,0043330,0070849,0005515,0005737,0005819,0045727,0006974,0010800 P63086 23790491 PEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVADLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKILDFGLARVADPLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKDLPKEKLKELIFEETARFQPGY 4i9f A 2.21 BS01 CA A 1 D14 D16 D209 D214 D13 D15 D208 D213 O33194 23801751 KSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGIDDGLSIVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSD 4i9f B 2.21 BS01 CA B 1 L292 I295 L292 I295 O33194 23801751 MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLSIVRAVASAVWEARPLRIEAGDERARAALQRWSLMRSDHPVTSVGT 4i9g A 3.25 BS01 MG A 1 D14 D16 D209 D15 D17 D210 O33194 23801751 HMKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCELGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDAVVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMDPRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVYAEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDIDDGLSIVRAVASAVWEARPLRIEAGDERARAALQRWSLM 4ieh A 2.10 BS01 1E9 A 1 A59 D62 F63 R66 Y67 F71 M74 V92 E95 L96 G104 R105 V107 A108 F112 V115 F157 Y161 A34 D37 F38 R41 Y42 F46 M49 V67 E70 L71 G79 R80 V82 A83 F87 V90 F132 Y136 0043066,1900118,0090005,0005634,0001541,0071312,0005813,0019050,0001701,0005622,0060154,0031965,0005856,1902230,0007093,0005741,0045087,0097193,0008283,0035872,0019901,2001244,0007283,0051881,2001240,0005737,0097136,0009566,0071480,0005815,0031966,0016020,0016021,0046902,0090201,0001836,0007281,0009314,0009615,0043065,0043524,0071230,0005515,0000910,0034097,0005829,0008584,0046982,2001243,0008284,0040007,0046898,0005739,0008637,0006915 P10415 YDNREIVMKYIHYKLSQRGYEWDSEVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP 4ihs A 3.10 BS01 NUC E 1 R4 Y8 I27 A28 P30 P31 R34 Q35 G51 S52 R53 R4 Y8 I27 A28 P30 P31 R34 Q35 G51 S52 R53 0003677,0006355,0019439,0006351 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGH 4ihs A 3.10 BS02 NUC F 1 S17 F18 T19 Q29 P30 S33 R34 Q37 R50 R53 S17 F18 T19 Q29 P30 S33 R34 Q37 R50 R53 0003677,0006355,0019439,0006351 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGH 4ihs A 3.10 BS03 NUC H 1 S87 G88 S87 G88 0003677,0006355,0019439,0006351 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGH 4ihs C 3.10 BS01 NUC F 1 S87 G88 H89 S87 G88 H89 0006355,0019439,0003677,0006351 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGHH 4ihs C 3.10 BS02 NUC G 1 R4 Y8 I27 A28 P30 P31 R34 Q35 R53 R4 Y8 I27 A28 P30 P31 R34 Q35 R53 0006355,0019439,0003677,0006351 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGHH 4iht A 3.00 BS02 NUC F 1 S17 F18 T19 Q29 P30 S33 R50 R53 S17 F18 T19 Q29 P30 S33 R50 R53 0006355,0019439,0003677,0006351 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGH 4iht B 3.00 BS01 NUC E 1 S17 F18 T19 Q29 P30 S33 Q37 R53 S17 F18 T19 Q29 P30 S33 Q37 R53 0019439,0003677,0006351,0006355 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIASGHH 4iht C 3.00 BS02 NUC H 1 S17 F18 T19 Q29 P30 S33 Q37 R50 R53 V55 S17 F18 T19 Q29 P30 S33 Q37 R50 R53 V55 0019439,0003677,0006351,0006355 O68014 MELRHLRYFVAVVEEQSFTKAADKLCIAQPPLSRQIQNLEEELGIQLLERGSRPVKTTPEGHFFYQYAIKLLSNVDQMVSMTKRIA 4ikw A 2.00 BS01 SO4 A 1 Y40 R43 Y78 E310 Y38 R41 Y76 E308 23798427 SIDKQQIAASVPQRGFFGHPKGLFTLFFTEFWERFSYYGMRAILVYYMYYEVSKGGLGLDEHLALAIMSIYGALVYMSGIIGGWLADRVFGTSRAVFYGGLLIMAGHIALAIPGGVAALFVSMALIVLGTGLLKPNVSSIVGDMYKPGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLVVFVATRKKNLGLAGTYVPNPLTPAEKKKAAAIMAVGAVVIAVLLAILIPNGWFTVETFISLVGILGIIIPIIYFVVMYRSPKTTAEERSRVIAYIPLFVASAMFWAIQEQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFIIILAPVFAWMWVKLGKRQPTIPQKFALGLLFAGLSFIVILVPGHLSGGGLVHPIWLVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQAINAQLVRFYTPENETAYFGTIGGAALVLGLILLAIAPRIGRLMKG 4iky A 2.10 BS01 SO4 A 1 Y40 R43 Y78 Q310 Y38 R41 Y76 Q308 23798427 SIDKQQIAASVPQRGFFGHPKGLFTLFFTEFWERFSYYGMRAILVYYMYYEVSKGGLGLDEHLALAIMSIYGALVYMSGIIGGWLADRVFGTSRAVFYGGLLIMAGHIALAIPGGVAALFVSMALIVLGTGLLKPNVSSIVGDMYKPGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLVVFVATRKKNLGLAGTYVPNPLTPAEKKKAAAIMAVGAVVIAVLLAILIPNGWFTVETFISLVGILGIIIPIIYFVVMYRSPKTTAEERSRVIAYIPLFVASAMFWAIQQQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFIIILAPVFAWMWVKLGKRQPTIPQKFALGLLFAGLSFIVILVPGHLSGGGLVHPIWLVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQAINAQLVRFYTPENETAYFGTIGGAALVLGLILLAIAPRIGRLMKG 4ikz A 2.40 BS01 AFS A 1 Y40 R43 Y78 A169 Q309 Q310 N342 P343 Y38 R41 Y76 A167 Q300 Q301 N333 P334 23798427 SIDKQQIAASVPQRGFFGHPKGLFTLFFTEFWERFSYYGMRAILVYYMYYEVSKGGLGLDEHLALAIMSIYGALVYMSGIIGGWLADRVFGTSRAVFYGGLLIMAGHIALAIPGGVAALFVSMALIVLGTGLLKPNVSSIVGDMYKPGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLVVFVATRKKNLGLAGTYVPNPLTPAEKKKAAAIMAVGAVVIAVLLAFTVETFISLVGILGIIIPIIYFVVMYRSPKTTAEERSRVIAYIPLFVASAMFWAIQQQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFIIILAPVFAWMWVKLGKRQPTIPQKFALGLLFAGLSFIVILVPGHLSGGGLVHPIWLVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQAINAQLVRFYTPENETAYFGTIGGAALVLGLILLAIAPRIGRLMKG 4ip2 A 1.95 BS01 MG A 1 H188 E229 H193 E234 Q9I6N5 23671667 LYFQSMNRSALDFRHFVDHLRRQGDLVDVHTEVDANLEIGAITRRVYERRAPAPLFHNIRDSLPGARVLGAPAGLRADRARAHSRLALHFGLPEHSGPRDIVAMLRAAMRAEPIAPRRLERGPVQENVWLGEQVDLTRFPVPLLHEQDGGRYFGTYGFHVVQTPDGSWDSWSVGRLMLVDRNTLAGPTIPTQHIGIIREQWRRLGKPTPWAMALGAPPAALAAAGMPLPEGVSEAGYVGALVGEPVEVVRTQTNGLWVPANTEIVLEGEISLDETALEGPMGEYHGYSFPIGKPQPLFHVHALSFRDQPILPICVAGTPPEENHTIWGTMISAQLLDVAQNAGLPVDMVWCSYEAATCWAVLSIDVQRLAALGTDAAAFAARVAETVFGSHAGHLVPKLILVGNDIDVTEIDQVVWALATRAHPLHDHFAFPQIRDFPMVPYLDAEDKARGSGGRLVINCLYPEQFAGQMRAATASFRHAYPTALRRRVEERWSDYGFG 4iru B 3.20 BS02 GDP B 1 G21 V22 G23 K24 S25 C26 Y36 Y40 I41 N124 K125 D127 L128 S154 A155 K156 G15 V16 G17 K18 S19 C20 Y30 Y34 I35 N118 K119 D121 L122 S148 A149 K150 3.6.5.2 0005783,0006810,0000166,0015031,0000139,0006184,0016192,0000278,0005794,0003924,0005525 P62820 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM 4iru F 3.20 BS01 MG F 1 K24 S25 T43 D66 K18 S19 T37 D60 3.6.5.2 0005783,0000166,0005525,0003924,0000139,0006184,0015031,0016192,0000278,0006810,0005794 P62820 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM 4iru F 3.20 BS02 GDP F 1 D19 G21 V22 G23 K24 S25 C26 Y36 E38 Y40 N124 K125 L128 S154 A155 K156 D13 G15 V16 G17 K18 S19 C20 Y30 E32 Y34 N118 K119 L122 S148 A149 K150 3.6.5.2 0005783,0000166,0005525,0003924,0000139,0006184,0015031,0016192,0000278,0006810,0005794 P62820 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM 4iru F 3.20 BS03 AF3 F 1 D19 S20 G21 K24 T43 T67 Q70 D13 S14 G15 K18 T37 T61 Q64 3.6.5.2 0005783,0000166,0005525,0003924,0000139,0006184,0015031,0016192,0000278,0006810,0005794 P62820 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM 4j1z A 2.00 BS02 495 A 1 H1031 G1032 Y1050 Y1060 K1067 S1068 Y1071 E1138 H80 G81 Y99 Y109 K116 S117 Y120 E186 2.4.2.30 Q9H2K2 23672613 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4j1z B 2.00 BS02 495 B 1 H1031 G1032 Y1050 Y1060 A1062 K1067 S1068 Y1071 E1138 H80 G81 Y99 Y109 A111 K116 S117 Y120 E186 2.4.2.30 Q9H2K2 23672613 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE 4j4m A 1.80 BS01 ZN A 1 H144 H148 H154 H141 H145 H151 3.4.24.53 23732127 RFPQRYVMLAIVADHGMVTKYSGNSSAITTRVHQMVSHVTEMYSPLNIATTLSLLRIWSSKDLITVQSDSSVTLGSFGDWRKVVLLSQQAHDCAFLNTATALDDSTIGLAYSNGMCDPKFSVGLVQDHSSNVFMVAVTMTHELGHNLGMAHDECSSCIMSPAASSGPSKLFSDCSKDDYQTFLTNTNPQCILNAP 4j4m A 1.80 BS02 ZN A 2 D72 D106 D69 D103 3.4.24.53 23732127 RFPQRYVMLAIVADHGMVTKYSGNSSAITTRVHQMVSHVTEMYSPLNIATTLSLLRIWSSKDLITVQSDSSVTLGSFGDWRKVVLLSQQAHDCAFLNTATALDDSTIGLAYSNGMCDPKFSVGLVQDHSSNVFMVAVTMTHELGHNLGMAHDECSSCIMSPAASSGPSKLFSDCSKDDYQTFLTNTNPQCILNAP 4j56 A 2.37 BS01 FAD A 1 G48 G50 P51 G52 D71 Y72 K74 G86 T87 C88 V91 G92 C93 K96 L160 A161 A191 T192 G193 S212 V233 R316 D319 L323 G356 D357 E364 L365 A366 P367 Y398 G11 G13 P14 G15 D34 Y35 K37 G49 T50 C51 V54 G55 C56 K59 L123 A124 A154 T155 G156 S175 V196 R279 D282 L286 G319 D320 E327 L328 A329 P330 Y361 1.8.1.9 P61076 HTYDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHYAGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVKLYMEEQGVMFKNGILPKKLTKMDDKILVEFSDKTSELYDTVLYAIGRKGDIDGLNLESLNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFKDSDEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPTDAESFMNLFVTISSGLSYAAKGGSGGGKCG 4j56 B 2.37 BS01 FAD A 1 H509 P510 H472 P473 1.8.1.9 P61076 HTYDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHYAGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVKLYMEEQGVMFKNGILPKKLTKMDDKILVEFSDKTSELYDTVLYAIGRKGDIDGLNLESLNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFKDSDEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPTDAESFMNLFVTISSGLSYAAKGGSGGGKCG 4j56 C 2.37 BS01 FAD C 1 G48 G50 P51 G52 D71 Y72 V73 K74 G86 T87 C88 G92 C93 K96 G159 L160 A161 T192 G193 S212 V233 R316 D319 G356 D357 E364 L365 P367 Y398 G11 G13 P14 G15 D34 Y35 V36 K37 G49 T50 C51 G55 C56 K59 G122 L123 A124 T155 G156 S175 V196 R279 D282 G319 D320 E327 L328 P330 Y361 1.8.1.9 P61076 HTYDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHYAGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVKLYMEEQGVMFKNGILPKKLTKMDDKILVEFSDKTSELYDTVLYAIGRKGDIDGLNLESLNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFKDSDEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDNCIGIHPTDAESFMNLFVTISSGLSYAAKGGSGGGKCG 4j93 A 1.74 BS01 0OE A 1 W80 M96 R97 E98 W117 H120 P122 I124 P125 R132 W80 M96 R97 E98 W117 H120 P122 I124 P125 R132 Q79791 PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS 4j93 A 1.74 BS02 1JR A 1 N53 L56 N57 M66 K70 I73 T107 Y130 N53 L56 N57 M66 K70 I73 T107 Y130 Q79791 PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS 4jdf A 1.69 BS01 SPD A 1 W37 T38 E39 Y40 E185 W244 W276 D278 Y314 W9 T10 E11 Y12 E157 W216 W248 D250 Y286 0043190,0042597,0006810,0015594,0015847 P31133 23792166 QKTLHIYNWTEYIAPDTVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSAYFLERQLTAGVFQPLDKSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSWDLILKPENLEKLKSCGVSFLDDPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLRPNIRYFHSSQYINDLANGDICVAIGWAGSVWQASNRAKEAKNGVNVSFSIPKEGAMAWFDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRENPGIYPPADVRAKLFTQKVQDPKIDRVRTRAWTKVKSG 4jhj A 3.25 BS01 III C 1 R76 R77 N81 Q84 F87 V117 N118 M120 P121 M122 V123 A124 L125 P128 R70 R71 N75 Q78 F81 V111 N112 M114 P115 M116 V117 A118 L119 P122 0005737,0005634,0006417 Q5EAQ1 23804756 EDYKIQSFDLETQKLLKTALKDPGSVDLEKVSSVIVDQSLKDQVFSREAGRICYTIVQAEAKQTNGSVFRRNLLNRLQQEFKAREETRKRSTQEWVCLVSFICNIFDYLKVNNMPMVALVHPVYDCLFRLAQSDALKNEEEVDCLVLQLHRIGDQLEKMNVQLMDELFNLLRDGFLLQEDLSSMGRLLLLEILEFRAGGWKLSDTAQKYYYSEVTD 4jhj A 3.25 BS02 III D 1 N119 M120 V123 H127 K164 M165 N113 M114 V117 H121 K158 M159 0005737,0005634,0006417 Q5EAQ1 23804756 EDYKIQSFDLETQKLLKTALKDPGSVDLEKVSSVIVDQSLKDQVFSREAGRICYTIVQAEAKQTNGSVFRRNLLNRLQQEFKAREETRKRSTQEWVCLVSFICNIFDYLKVNNMPMVALVHPVYDCLFRLAQSDALKNEEEVDCLVLQLHRIGDQLEKMNVQLMDELFNLLRDGFLLQEDLSSMGRLLLLEILEFRAGGWKLSDTAQKYYYSEVTD 4jhj B 3.25 BS01 III C 1 N119 M120 P121 V123 H127 K164 M165 N166 N113 M114 P115 V117 H121 K158 M159 N160 0005634,0006417,0005737 Q5EAQ1 23804756 EDYKIQSFDLETQKLLKTALKDPGSVDLEKVSSVIVDQSLKDQVFSREAGRICYTIVQAEAKQTNGSVFRRNLLNRLQQEFKAREETRKRSTQEWVCLVSFICNIFDYLKVNNMPMVALVHPVYDCLFRLAQSDALKNEEEVDCLVLQLHRIGDQLEKMNVQLMDELFNLLRDGFLLQEDLSSMGRLLLLEILEFRAGGWKLSDTAQKYYY 4jhj B 3.25 BS02 III D 1 R76 R77 L80 N81 Q84 F87 V117 N118 M120 P121 M122 V123 A124 L125 P128 R70 R71 L74 N75 Q78 F81 V111 N112 M114 P115 M116 V117 A118 L119 P122 0005634,0006417,0005737 Q5EAQ1 23804756 EDYKIQSFDLETQKLLKTALKDPGSVDLEKVSSVIVDQSLKDQVFSREAGRICYTIVQAEAKQTNGSVFRRNLLNRLQQEFKAREETRKRSTQEWVCLVSFICNIFDYLKVNNMPMVALVHPVYDCLFRLAQSDALKNEEEVDCLVLQLHRIGDQLEKMNVQLMDELFNLLRDGFLLQEDLSSMGRLLLLEILEFRAGGWKLSDTAQKYYY 4jtw A 3.00 BS01 1NU A 1 L419 R422 M423 L474 H475 S476 Y477 I482 V485 A486 L497 W528 L416 R419 M420 L471 H472 S473 Y474 I479 V482 A483 L494 W525 3.4.22.-,3.4.21.98,3.6.1.15,3.6.4.13,2.7.7.48 O92972 23773186 SMSYTWTGALITPCAAEESKLPINPLSNSLLRHHNMVYATTSRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSIEEACKLTPPHSAKSKFGYGAKDVRNLSSRAVNHIRSVWEDLLEDTETPIDTTIMAKSEVFCVQPGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQRVEFLVNTWKSKKCPMGFSYDTRCFDSTVTESDIRVEESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKATAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAAALRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPINSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFTLHSYSPGEINRVASCLRKLGVPPLRTWRHRARSVRAKLLSQGGRAATCGRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYHS 4jtw A 3.00 BS03 MG A 2 T221 C223 F224 T218 C220 F221 3.4.22.-,3.4.21.98,3.6.1.15,3.6.4.13,2.7.7.48 O92972 23773186 SMSYTWTGALITPCAAEESKLPINPLSNSLLRHHNMVYATTSRSASLRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSIEEACKLTPPHSAKSKFGYGAKDVRNLSSRAVNHIRSVWEDLLEDTETPIDTTIMAKSEVFCVQPGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPKQRVEFLVNTWKSKKCPMGFSYDTRCFDSTVTESDIRVEESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKATAACRAAKLQDCTMLVNGDDLVVICESAGTQEDAAALRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPINSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFTLHSYSPGEINRVASCLRKLGVPPLRTWRHRARSVRAKLLSQGGRAATCGRYLFNWAVRTKLKLTPIPAASQLDLSGWFVAGYSGGDIYHS 4k3i A 2.00 BS03 HEC A 2 W93 N200 C201 C204 H205 H224 I226 L228 F264 P267 L269 Y278 M279 H280 L287 Y294 S324 E327 W88 N195 C196 C199 H200 H219 I221 L223 F259 P262 L264 Y273 M274 H275 L282 Y289 S319 E322 1.-.-.- 0055114,0022900,0046872,0042597,0016491 Q51658 ADDALAALGAQLFVDPALSRNATQSCATCHDPARAFTDPREGKAGLAVSVGDDGQSHGDRNTPTLGYAALVPAFHRDANGKYKGGQFWDGRADDLKQQAGQPMLNPVEMAMPDRAAVAARLRDDPAYRTGFEALFGKGVLDDPERAFDAAAEALAAYQATGEFSPFDSKYDRVMRGEEKFTPLEEFGYTVFITWNCRLCHMQRKQGVAERETFTNFEYHNIGLPVNETAREASGLGADHVDHGLLARPGIEDPAQSGRFKVPSLRNVAVTGPYMHNGVFTDLRTAILFYNKYTSRRPEAKINPETGAPWGEPEVARNLSLAELQSGLMLDDGRVDALVAFLETLTDRRYEPLLE 4k6n A 1.90 BS01 PLP A 1 R128 K251 R255 Y258 E297 G298 S299 T301 N302 L326 G328 T329 M330 N360 G361 R106 K229 R233 Y236 E275 G276 S277 T279 N280 L304 G306 T307 M308 N338 G339 4.1.3.38 Q03266 PNFEVLATFRYDPGFARQSASKKEIFETPDPRLGLRDEDIRQQIINEDYSSYLRVREVNSGGDLLENIQHPDAWKHDCKTIVCQRVEDMLQVIYERFFLLDEQYQRIRIALSYFKIDFSTSLNDLLKLLVENLINCKEGNSEYHEKIQKMINERQCYKMRVLVSKTGDIRIEAIPMPMEPILKLTTDYDSVSTYFIKTMLNGFLIDSTINWDVVVSSEPLNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCEILFSNKSGLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGLIEEGDIDIGSLTVGNEVLLFNGVMGCIKGTVKTKY 4k8s A 2.39 BS01 1QT A 1 L30 D32 G34 P70 Y71 T72 F108 I118 Y198 K224 D228 G230 T231 T329 V332 L33 D35 G37 P73 Y74 T75 F111 I121 Y190 K216 D220 G222 T223 T315 V318 3.4.23.46 P56817 23769639 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4k8s B 2.39 BS01 1QT B 1 L30 D32 G34 S35 P70 Y71 T72 F108 Y198 K224 D228 G230 L33 D35 G37 S38 P73 Y74 T75 F111 Y190 K216 D220 G222 3.4.23.46 P56817 23769639 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4k8s C 2.39 BS01 1QT C 1 L30 D32 G34 P70 Y71 T72 F108 R128 Y198 D228 G230 T231 R235 L33 D35 G37 P73 Y74 T75 F111 R131 Y190 D220 G222 T223 R227 3.4.23.46 P56817 23769639 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4k9h A 2.29 BS01 1QU A 1 D32 G34 S35 P70 Y71 T72 Q73 F108 I110 I118 Y198 D228 G230 T231 T232 N233 R235 D35 G37 S38 P73 Y74 T75 Q76 F111 I113 I121 Y190 D220 G222 T223 T224 N225 R227 3.4.23.46 P56817 23769639 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4k9h B 2.29 BS01 1QU B 1 Q12 G13 D32 G34 S35 V69 P70 Y71 T72 Q73 F108 I110 I118 Y198 D228 G230 T231 T232 N233 R235 Q15 G16 D35 G37 S38 V72 P73 Y74 T75 Q76 F111 I113 I121 Y189 D219 G221 T222 T223 N224 R226 3.4.23.46 P56817 23769639 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4k9h C 2.29 BS01 1QU C 1 G11 Q12 G13 L30 D32 G34 S35 P70 Y71 T72 Q73 F108 I110 D228 G230 T231 T232 N233 R235 G14 Q15 G16 L33 D35 G37 S38 P73 Y74 T75 Q76 F111 I113 D220 G222 T223 T224 N225 R227 3.4.23.46 P56817 23769639 SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN 4kew A 1.89 BS01 HEM A 1 K69 L86 F87 W96 F107 F261 A264 G265 T268 T269 T327 A328 F331 P392 F393 G394 R398 A399 C400 I401 G402 F405 A406 K67 L84 F85 W94 F105 F256 A259 G260 T263 T264 T322 A323 F326 P387 F388 G389 R393 A394 C395 I396 G397 F400 A401 1.14.14.1,1.6.2.4 P14779 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4kew A 1.89 BS02 1C6 A 1 V26 Y51 A74 F87 L188 I263 A264 A328 P329 A330 L437 T438 V24 Y49 A72 F85 L186 I258 A259 A323 P324 A325 L432 T433 1.14.14.1,1.6.2.4 P14779 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4kew B 1.89 BS01 HEM B 1 K69 L75 L86 F87 W96 F107 F261 A264 G265 T268 T269 L272 T327 A328 F331 P392 F393 G394 R398 A399 C400 I401 G402 F405 A406 K62 L68 L79 F80 W89 F100 F249 A252 G253 T256 T257 L260 T315 A316 F319 P380 F381 G382 R386 A387 C388 I389 G390 F393 A394 1.14.14.1,1.6.2.4 P14779 KEMPQPLKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4kew B 1.89 BS02 1C6 B 1 V26 A74 F87 L188 I263 A264 A328 P329 A330 L437 T438 V19 A67 F80 L181 I251 A252 A316 P317 A318 L425 T426 1.14.14.1,1.6.2.4 P14779 KEMPQPLKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4key A 2.05 BS02 1C6 A 1 V26 Y51 A74 L188 A328 P329 L437 V24 Y49 A72 L186 A323 P324 L432 1.14.14.1,1.6.2.4 P14779 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4key B 2.05 BS02 1C6 B 1 V26 A264 A328 P329 A330 L437 V18 A251 A315 P316 A317 L424 1.14.14.1,1.6.2.4 P14779 KEMPQPKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPL 4kf2 B 1.82 BS01 HEM B 1 K69 L86 V87 W96 F107 I153 F261 A264 G265 T268 T269 L272 T327 A328 F331 P392 F393 G394 R398 A399 C400 I401 G402 F405 A406 K67 L84 V85 W94 F105 I151 F253 A256 G257 T260 T261 L264 T319 A320 F323 P384 F385 G386 R390 A391 C392 I393 G394 F397 A398 1.14.14.1,1.6.2.4 P14779 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRDPAYDENKRQFQEDIKVMNDLVDKIIADRKASQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLG 4kis A 3.20 BS01 NUC E 1 R135 M136 G139 K140 R143 T152 A153 K154 R156 S189 T191 Y207 N208 M254 N261 K262 K286 T288 S290 R291 K293 Y295 Y297 Y299 H309 K313 R2 M3 G6 K7 R10 T19 A20 K21 R23 S56 T58 Y74 N75 M121 N128 K129 K153 T155 S157 R158 K160 Y162 Y164 Y166 H176 K180 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMNDIDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis A 3.20 BS02 NUC F 1 M136 G155 R156 T206 N208 R209 N212 Y225 K226 P258 N259 S264 S266 N269 H283 R285 T288 K303 K306 M3 G22 R23 T73 N75 R76 N79 Y92 K93 P125 N126 S131 S133 N136 H150 R152 T155 K170 K173 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMNDIDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis A 3.20 BS03 ZN A 1 C274 K276 C277 C302 C314 C141 K143 C144 C169 C181 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMNDIDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis A 3.20 BS04 ZN A 2 H455 H457 H459 H310 H312 H314 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMNDIDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis A 3.20 BS05 ZN A 3 H458 H460 H313 H315 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMNDIDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis A 3.20 BS06 CA A 1 D330 N334 D197 N201 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMNDIDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis B 3.20 BS01 NUC G 1 R135 M136 G139 K140 R143 T152 A153 K154 R156 S189 T191 Y207 N208 M254 N261 K262 K286 T288 S290 K293 Y295 Y297 Y299 K313 R320 R2 M3 G6 K7 R10 T19 A20 K21 R23 S56 T58 Y74 N75 M121 N128 K129 K153 T155 S157 K160 Y162 Y164 Y166 K180 R187 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFELDSLNEKLKIEHAKKKRLFDLYSELDSMMNDIDAQINYYEAQIEANEELKKNKKIQENLADLATVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLE 4kis B 3.20 BS02 NUC H 1 M136 V137 L150 G155 R156 T206 N208 R209 N212 Y225 K226 N259 S264 S266 N269 V282 H283 R285 T288 K303 K306 M3 V4 L17 G22 R23 T73 N75 R76 N79 Y92 K93 N126 S131 S133 N136 V149 H150 R152 T155 K170 K173 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFELDSLNEKLKIEHAKKKRLFDLYSELDSMMNDIDAQINYYEAQIEANEELKKNKKIQENLADLATVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLE 4kis C 3.20 BS01 NUC I 1 R135 M136 G139 K140 R143 A153 K154 R156 S189 T191 Y207 M254 N259 N261 K262 K286 T288 S290 K293 Y295 Y297 Y299 K313 R320 R2 M3 G6 K7 R10 A20 K21 R23 S56 T58 Y74 M121 N126 N128 K129 K153 T155 S157 K160 Y162 Y164 Y166 K180 R187 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDELDSLNEKLKIEHAKKKRLFDLYDSMMNDIDAQINYYEAQIEANEELKKNKKIQENLADLATVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWL 4kis C 3.20 BS02 NUC J 1 M136 K140 G155 R156 T206 N208 R209 Y225 K226 N259 S264 A265 S266 N269 N270 V282 H283 R285 T288 K303 K306 M3 K7 G22 R23 T73 N75 R76 Y92 K93 N126 S131 A132 S133 N136 N137 V149 H150 R152 T155 K170 K173 Q928V6 DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKEDELDSLNEKLKIEHAKKKRLFDLYDSMMNDIDAQINYYEAQIEANEELKKNKKIQENLADLATVDFNSLEFREKQLYLKSLINKIYIDGEQVTIEWL 4kis D 3.20 BS01 NUC K 1 R135 M136 G139 K140 R143 T152 A153 K154 R156 T165 S189 T191 Y207 N208 M254 N261 K262 K286 T288 S290 R291 K293 Y295 Y297 Y299 H309 K313 I318 R320 R3 M4 G7 K8 R11 T20 A21 K22 R24 T33 S57 T59 Y75 N76 M122 N129 K130 K154 T156 S158 R159 K161 Y163 Y165 Y167 H177 K181 I186 R188 Q928V6 RDRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKELNEKLKIEIDAQINYYEAQIEANEELKKNKKIQEFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis D 3.20 BS02 NUC L 1 R133 M136 L150 G155 R156 T206 R209 N212 Y225 K226 N259 S264 S266 N269 N270 V282 H283 R285 T288 K303 K306 R1 M4 L18 G23 R24 T74 R77 N80 Y93 K94 N127 S132 S134 N137 N138 V150 H151 R153 T156 K171 K174 Q928V6 RDRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKELNEKLKIEIDAQINYYEAQIEANEELKKNKKIQEFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kis D 3.20 BS03 ZN D 1 C274 K276 C277 C302 C314 C142 K144 C145 C170 C182 Q928V6 RDRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDIFEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKGIHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNIDKELNEKLKIEIDAQINYYEAQIEANEELKKNKKIQEFNSLEFREKQLYLKSLINKIYIDGEQVTIEWLLEHHHHHH 4kl8 S 1.52 BS02 SF4 S 2 I207 T242 C246 W251 C258 C264 I265 C267 V268 I203 T238 C242 W247 C254 C260 I261 C263 V264 1.12.99.6 0055114,0033748,0046872,0042597,0051536,0051539,0016491 P13063 AKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE 4kl8 L 1.52 BS03 FCO L 1 C73 H77 A423 P424 R425 A447 T448 A492 C495 C64 H68 A414 P415 R416 A438 T439 A483 C486 1.12.99.6 C7LN88 GKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKNFRDLGDKAFSIMGRHVARAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPALGCAVH 4kl8 T 1.52 BS02 SF4 T 2 I207 T242 C246 W251 W257 C258 C264 I265 G266 C267 I203 T238 C242 W247 W253 C254 C260 I261 G262 C263 1.12.99.6 0051536,0055114,0046872,0051539,0033748,0042597,0016491 P13063 AKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE 4kl8 T 1.52 BS04 CA T 1 D271 G275 D267 G271 1.12.99.6 0051536,0055114,0046872,0051539,0033748,0042597,0016491 P13063 AKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE 4kl8 T 1.52 BS05 CA T 2 D195 D196 D191 D192 1.12.99.6 0051536,0055114,0046872,0051539,0033748,0042597,0016491 P13063 AKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE 4kl8 M 1.52 BS03 FCO M 1 C73 H77 A423 P424 R425 L428 A447 T448 A492 C495 C64 H68 A414 P415 R416 L419 A438 T439 A483 C486 1.12.99.6 C7LN88 GKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKNFRDLGDKAFSIMGRHVARAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPALGCAVH 4kl8 M 1.52 BS05 CA M 2 D17 P18 H25 L26 D8 P9 H16 L17 1.12.99.6 C7LN88 GKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKNFRDLGDKAFSIMGRHVARAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPALGCAVH 4kn9 L 1.40 BS03 FCO L 1 C70 C73 H77 A423 P424 R425 A447 T448 C492 C495 C61 C64 H68 A414 P415 R416 A438 T439 C483 C486 1.12.99.6 C7LN88 GKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKNFRDLGDKAFSIMGRHVARAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPCLGCAVH 4ko1 L 1.55 BS03 FCO L 1 C73 H77 A423 P424 R425 A447 T448 C492 C495 C64 H68 A414 P415 R416 A438 T439 C483 C486 1.18.99.1 C7LN88 GKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKNFRDLGDKAFSIMGRHVARAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPCLGCAVH 4ko1 T 1.55 BS02 SF4 T 2 I207 T242 C246 W251 W257 C258 C264 I265 C267 I203 T238 C242 W247 W253 C254 C260 I261 C263 1.12.99.6 0033748,0046872,0042597,0051536,0051539,0016491,0055114 P13063 AKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE 4ko3 S 1.70 BS02 SF4 S 2 I207 T242 C246 W251 C258 C264 I265 C267 I203 T238 C242 W247 C254 C260 I261 C263 1.12.99.6 0051536,0033748,0051539,0042597,0016491,0046872,0055114 P13063 AKKAPVIWVQGQGCTGCSVSLLNAVHPRIKEILLDVISLEFHPTVMASEGEMALAHMYEIAEKFNGNFFLLVEGAIPTAKEGRYCIVGETLDAKGHHHEVTMMELIRDLAPKSLATVAVGTCSAYGGIPAAEGNVTGSKSVRDFFADEKIEKLLVNVPGCPPHPDWMVGTLVAAWSHVLNPTEHPLPELDDDGRPLLFFGDNIHENCPYLDKYDNSEFAETFTKPGCKAELGCKGPSTYADCAKRRWNNGINWCVENAVCIGCVEPDFPDGKSPFYVAE 4kp3 A 2.40 BS01 III E 1 D1524 V1527 R1528 T1532 I1535 N1536 K1539 S1570 L1588 T1589 N1590 F1591 D1592 L1593 E1595 Y1596 D55 V58 R59 T63 I66 N67 K70 S101 L119 T120 N121 F122 D123 L124 E126 Y127 Q99104 23798443 DFQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETTYTLDSILRQLNSFHSVMSQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIARV 4kp3 B 2.40 BS01 III F 1 D1524 R1528 T1532 N1536 K1539 S1570 T1589 N1590 F1591 D1592 E1595 Y1596 V1599 D55 R59 T63 N67 K70 S101 T120 N121 F122 D123 E126 Y127 V130 Q99104 23798443 DFQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETYTLDSILRQLNSFHSVMSQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIARV 4kp6 A 1.50 BS01 1S1 A 1 H234 M347 N395 Y403 T407 I410 F414 M431 S442 Q443 F446 H73 M186 N234 Y242 T246 I249 F253 M270 S281 Q282 F285 3.1.4.17 Q07343 23806553 NEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIP 4ksz A 1.98 BS01 HEM A 1 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 V354 F380 L417 L433 I436 R440 M101 G104 Q105 D108 D112 F113 A114 R255 E258 Q259 T344 F347 R348 G350 H351 V354 F380 L417 L433 I436 R440 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 4ksz A 1.98 BS03 CYS A 1 R255 E258 F381 R255 E258 F381 1.11.1.7 P80025 SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN 4kw5 A 2.61 BS02 1W6 A 1 Y60 H132 G133 K134 S228 W230 Y314 Q334 V365 K367 N385 K418 Y54 H126 G127 K128 S222 W224 Y293 Q299 V330 K332 N350 K383 1.1.98.3 I6X8C4 23776209 TTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGGRGAIARGLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTADGEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQLPAKLRSEPLKFDANKYTFGPIGELWYRKSGTYRGKVQNLTQFYHPGFLQYQFVIPTEAVDEFKKIIGVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLELL 4kw5 B 2.61 BS02 1W6 B 1 Y60 H132 K134 S228 W230 Y314 P316 Q336 C387 K418 Y54 H126 K128 S222 W224 Y282 P284 Q290 C341 K372 1.1.98.3 I6X8C4 23776209 TTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGGRGAIARGLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTADGEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQLPAKLRSEPLKFELWYRKSGTYRGKVQNLTQFYHPGFLQYQFVIPTEAVDEFKKIIGVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLELL 4l59 A 2.29 BS01 1VZ A 1 D274 H277 C282 F298 Y301 Y305 D43 H46 C51 F67 Y70 Y74 Q96JM7 WCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFEVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPL 4l89 A 1.60 BS01 COA A 1 E25 Y28 C29 M81 M82 V83 R88 G89 L90 G91 V92 A93 R94 N121 A123 L126 L127 Q130 E25 Y28 C29 M81 M82 V83 R88 G89 L90 G91 V92 A93 R94 N121 A123 L126 L127 Q130 0008080 Q9HV14 MQLSHRPAETGDLETVAGFPQDRDELFYCYPKAIWPFSVAQLAAAIAERRGSTVAVHDGQVLGFANFYQWQHGDFCALGNMMVAPAARGLGVARYLIGVMENLAREQYKARLMKISCFNANAAGLLLYTQLGYQPRAIAERHDPDGRRVALIQMDKPLE 4l8a A 1.20 BS01 COA A 1 Y28 C29 M81 M82 V83 R88 G89 L90 G91 V92 A93 R94 S116 C117 N121 A123 L126 L127 Y128 Y28 C29 M81 M82 V83 R88 G89 L90 G91 V92 A93 R94 S116 C117 N121 A123 L126 L127 Y128 0008080 Q9HV14 MQLSHRPAETGDLETVAGFPQDRDELFYCYPKAIWPFSVAQLAAAIAERRGSTVAVHDGQVLGFANFYQWQHGDFCALGNMMVAPAARGLGVARYLIGVMENLAREQYKARLMKISCFNANAAGLLLYTQLGYQPRAIAERHDPDGRRVALIQMDKPLE 4l8a A 1.20 BS02 1VP A 1 Y28 C29 P31 R49 Y68 L78 G79 N80 M81 I115 S116 F118 Y128 R141 H142 L151 Y28 C29 P31 R49 Y68 L78 G79 N80 M81 I115 S116 F118 Y128 R141 H142 L151 0008080 Q9HV14 MQLSHRPAETGDLETVAGFPQDRDELFYCYPKAIWPFSVAQLAAAIAERRGSTVAVHDGQVLGFANFYQWQHGDFCALGNMMVAPAARGLGVARYLIGVMENLAREQYKARLMKISCFNANAAGLLLYTQLGYQPRAIAERHDPDGRRVALIQMDKPLE 4l8r B 2.60 BS01 NUC A 1 Y66 K67 I69 A70 N73 G74 N77 R78 K104 K107 K111 D134 E136 A137 C139 E140 N143 F185 G231 S232 W233 F238 R261 K262 N266 K269 Q274 T275 K276 S329 S332 Y4 K5 I7 A8 N11 G12 N15 R16 K42 K45 K49 D65 E67 A68 C70 E71 N74 F116 G162 S163 W164 F169 R192 K193 N197 K200 Q202 T203 K204 S257 S260 3.1.-.- 0071044,0031047,0043022,0005730,0071207,0006364,0005634,0008408,0016787,0004527,0005737,0019843,0004518,0071204,0090305,0003723,0031125,0046872 Q8IV48 23329046 DPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMDSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVQTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFR 4l8r C 2.60 BS01 NUC A 1 R137 K140 Y144 Y178 S179 R180 R181 S182 Q185 K188 L189 K191 H195 D198 P199 R11 K14 Y18 Y46 S47 R48 R49 S50 Q53 K56 L57 K59 H63 D66 P67 Q14493 23329046 DFETDESVLMRRQKQINYGKNTIAYDRYIKEVPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDP 4l8r E 2.60 BS01 NUC D 1 Y66 K67 I69 A70 N73 G74 N77 K104 K107 E136 A137 T138 C139 E140 N143 F185 D230 G231 S232 W233 F238 R261 K262 N266 T275 H293 R317 S329 S332 Y3 K4 I6 A7 N10 G11 N14 K41 K44 E65 A66 T67 C68 E69 N72 F114 D159 G160 S161 W162 F167 R190 K191 N195 T199 H217 R241 S253 S256 3.1.-.- 0008408,0071044,0043022,0005730,0031047,0004518,0006364,0071204,0016787,0090305,0071207,0003723,0004527,0031125,0005634,0046872,0005737,0019843 Q8IV48 23329046 PVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKTKLTIMLEKLGMDYDGRPHCGLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRKL 4l9d B 1.10 BS01 CA B 1 A758 D780 D782 D821 K823 D825 A2 D24 D26 D65 K67 D69 C3LUP3 IAPVARFELKVEGLSVMSQNTSSDSDGNIVSYLWDFGNGQTSTEAAPTWSYTKAGSYSVTLTVTDDKGDSDTHQQTIKVDT 4lat A 1.88 BS01 PO4 A 1 S38 T39 A40 G67 S68 D86 R154 S158 G159 S160 S8 T9 A10 G37 S38 D56 R124 S128 G129 S130 Q97Q31 ESITAVGSTALQPLVEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVDHKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGSRATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYDLSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMKVEKDAAGTVTVLEG 4lep A 3.20 BS01 AFS A 1 R25 Y29 Y147 V150 N151 S154 N329 I333 E402 R17 Y21 Y139 V142 N143 S146 N304 I308 E371 Q8EHE6 SKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLTPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMHKSLANYGVNKKSLAIVLALAALSVVASAIILEYEDVARVFVYAAGVAVLGIFFHLIRPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFWTWSPAQFQALNPIWIMVLSPVLAWSYSWDFSIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWVMIWGYASYSLGELLVSGLGLAMIARYGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGVAAVVCTIIALAVLPLMRRLT 4lep B 3.20 BS01 AFS B 1 R25 Y29 V150 N151 N329 I333 E402 R16 Y20 V141 N142 N307 I311 E369 Q8EHE6 KTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLTPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMHKSLANYGSPVNKKSLAIVLALAALSVVASAIILEYEDVARVFVYAAGVAVLGIFFHLIRTPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFLWTWSPAQFQALNPIWIMVLSPVLAWSSIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWVMIWGYASYSLGELLVSGLGLAMIARGGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGVAAVVCTIIALAVLPLMRRL 4lfe A 1.95 BS01 IPE A 1 S74 L75 D78 D84 R89 M145 Q149 K172 S75 L76 D79 D85 R90 M146 Q150 K173 2.5.1.10 B9DUT7 SMDKLKKIDQTIHAFYCEKAVISEKLNEAVLYSINAGGKRIRPILFLEVIEALQIPLTESHFKAAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATAILAGDSLFLDAFGMLAETDFPTDVTVDLVRSLSSASGTFGMVGGQMLDMAAEGKKLNLKNLQLIHRHKTGQLLAYPFWAAARVAQLDENLLATFLEIGMIIGLAFQVRDDILDITAKMTYPHLLGLNESYQILDESLDQAEAILRKLSDEIAFAPQKILSLIERLRLDA 4lfe A 1.95 BS02 MG A 1 D78 D84 D79 D85 2.5.1.10 B9DUT7 SMDKLKKIDQTIHAFYCEKAVISEKLNEAVLYSINAGGKRIRPILFLEVIEALQIPLTESHFKAAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATAILAGDSLFLDAFGMLAETDFPTDVTVDLVRSLSSASGTFGMVGGQMLDMAAEGKKLNLKNLQLIHRHKTGQLLAYPFWAAARVAQLDENLLATFLEIGMIIGLAFQVRDDILDITAKMTYPHLLGLNESYQILDESLDQAEAILRKLSDEIAFAPQKILSLIERLRLDA 4lfe B 1.95 BS01 IPE B 1 D78 D84 R89 Q149 K172 T173 Q210 D213 K227 D77 D83 R88 Q148 K171 T172 Q209 D212 K226 2.5.1.10 B9DUT7 DKLKKIDQTIHAFYCEKAVISEKLNEAVLYSINAGGKRIRPILFLEVIEALQIPLTESHFKAAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATAILAGDSLFLDAFGMLAETDFPTDVTVDLVRSLSSASGTFGMVGGQMLDMAAEGKKLNLKNLQLIHRHKTGQLLAYPFWAAARVAQLDENLLATFLEIGMIIGLAFQVRDDILDITANFEEIGKTPKKDVMAEKMTYPHLLGLNESYQILDESLDQAEAILRKLSDEIAFAPQKILSLIERLRLDA 4lfe B 1.95 BS02 IPE B 2 G37 K38 R41 H71 L75 R90 T173 F209 Q210 D213 G36 K37 R40 H70 L74 R89 T172 F208 Q209 D212 2.5.1.10 B9DUT7 DKLKKIDQTIHAFYCEKAVISEKLNEAVLYSINAGGKRIRPILFLEVIEALQIPLTESHFKAAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATAILAGDSLFLDAFGMLAETDFPTDVTVDLVRSLSSASGTFGMVGGQMLDMAAEGKKLNLKNLQLIHRHKTGQLLAYPFWAAARVAQLDENLLATFLEIGMIIGLAFQVRDDILDITANFEEIGKTPKKDVMAEKMTYPHLLGLNESYQILDESLDQAEAILRKLSDEIAFAPQKILSLIERLRLDA 4lfg A 1.76 BS01 IPE A 1 L75 D78 D84 R89 M145 Q149 K172 T173 D217 K227 L76 D79 D85 R90 M146 Q150 K173 T174 D218 K228 2.5.1.10 B9DUT7 SMDKLKKIDQTIHAFYCEKAVISEKLNEAVLYSINAGGKRIRPILFLEVIEALQIPLTESHFKAAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATAILAGDSLFLDAFGMLAETDFPTDVTVDLVRSLSSASGTFGMVGGQMLDMAAEGKKLNLKNLQLIHRHKTGQLLAYPFWAAARVAQLDENLLATFLEIGMIIGLAFQVRDDILDITANFEEIGKTPKKDVMAEKMTYPHLLGLNESYQILDESLDQAEAILRKLSDEIAFAPQKILSLIERLRLDA 4lfy A 1.80 BS01 ZN A 1 H31 H33 K117 D268 H21 H23 K107 D253 3.5.2.3 B4EEU0 PPMTASNSPATLSLARPDDWHLHLRDGDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAALPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPASDHGVTDLAKCAKTLEAMQETGMPLLVHGEVTDASIDLFDREKVFIDRVMTPLRRDFPGLKVVFEHITTKDAADYVRDADAAPGLLGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKETACGCAGCYTALHALELYAEAFDTAGALDKLEGFASFFGADFYGLPRSAETVTLRREPWELPREIFAGETPVVPLRGGETIGWKLA 4lfy A 1.80 BS02 ZN A 2 K117 H154 H192 K107 H139 H177 3.5.2.3 B4EEU0 PPMTASNSPATLSLARPDDWHLHLRDGDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAALPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPASDHGVTDLAKCAKTLEAMQETGMPLLVHGEVTDASIDLFDREKVFIDRVMTPLRRDFPGLKVVFEHITTKDAADYVRDADAAPGLLGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKETACGCAGCYTALHALELYAEAFDTAGALDKLEGFASFFGADFYGLPRSAETVTLRREPWELPREIFAGETPVVPLRGGETIGWKLA 4lfy A 1.80 BS03 CA A 1 R225 R245 R210 R230 3.5.2.3 B4EEU0 PPMTASNSPATLSLARPDDWHLHLRDGDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAALPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPASDHGVTDLAKCAKTLEAMQETGMPLLVHGEVTDASIDLFDREKVFIDRVMTPLRRDFPGLKVVFEHITTKDAADYVRDADAAPGLLGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKETACGCAGCYTALHALELYAEAFDTAGALDKLEGFASFFGADFYGLPRSAETVTLRREPWELPREIFAGETPVVPLRGGETIGWKLA 4lfy A 1.80 BS04 CA A 2 R245 E246 T247 R230 E231 T232 3.5.2.3 B4EEU0 PPMTASNSPATLSLARPDDWHLHLRDGDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAALPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPASDHGVTDLAKCAKTLEAMQETGMPLLVHGEVTDASIDLFDREKVFIDRVMTPLRRDFPGLKVVFEHITTKDAADYVRDADAAPGLLGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKETACGCAGCYTALHALELYAEAFDTAGALDKLEGFASFFGADFYGLPRSAETVTLRREPWELPREIFAGETPVVPLRGGETIGWKLA 4lfy A 1.80 BS05 CA B 1 F165 R225 R245 F150 R210 R230 3.5.2.3 B4EEU0 PPMTASNSPATLSLARPDDWHLHLRDGDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAALPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPASDHGVTDLAKCAKTLEAMQETGMPLLVHGEVTDASIDLFDREKVFIDRVMTPLRRDFPGLKVVFEHITTKDAADYVRDADAAPGLLGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKETACGCAGCYTALHALELYAEAFDTAGALDKLEGFASFFGADFYGLPRSAETVTLRREPWELPREIFAGETPVVPLRGGETIGWKLA 4lg2 A 2.70 BS01 NUC E 1 F228 I329 F21 I122 Q8JPY0 ISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLADGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSPKIDRGWVCLFKMQDGKTLGLKI 4lg2 A 2.70 BS02 NUC F 1 I267 Q268 K271 R301 R311 I60 Q61 K64 R94 R104 Q8JPY0 ISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLADGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSPKIDRGWVCLFKMQDGKTLGLKI 4lg2 D 2.70 BS01 NUC J 1 C264 I267 Q268 K271 R272 R311 C57 I60 Q61 K64 R65 R104 Q8JPY0 ISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLADGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSPKIDRGWVCLFKMQDGKTLGLKI 4lg2 D 2.70 BS02 NUC I 1 F228 Q263 I267 I329 F21 Q56 I60 I122 Q8JPY0 ISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLADGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSPKIDRGWVCLFKMQDGKTLGLKI